#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:P17844	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6927869|imex:IM-21137-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene)|uniprotkb:P17844(identity)|refseq:NM_004396(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 425 nucleotides long and that maps to nucleotides 1517 to 1942 of the RefSeq entry NM_004396.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606	intact-crc:B1239488C4F7194B|rigid:yROHBny8HeSxSVO5ScDfw3+uksk	false	sufficient binding region:36-213|sufficient binding region:209-342	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P78344	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-296519|uniprotkb:O60877|uniprotkb:P78404|uniprotkb:Q0VH00|uniprotkb:Q53EU1|uniprotkb:Q58EZ2|uniprotkb:Q8NI71|uniprotkb:Q96C16|ensembl:ENSP00000340281|ensembl:ENSP00000433371|ensembl:ENSP00000433664|uniprotkb:Q0VH01|uniprotkb:Q2NKW9|uniprotkb:Q49A79	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:if4g2_human(display_long)|uniprotkb:EIF4G2(gene name)|psi-mi:EIF4G2(display_short)|uniprotkb:DAP5(gene name synonym)|uniprotkb:OK/SW-cl.75(orf name)|uniprotkb:p97(gene name synonym)|uniprotkb:Death-associated protein 5(gene name synonym)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6927888|imex:IM-21137-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110321(gene)|ensembl:ENST00000339995(transcript)|ensembl:ENST00000525681(transcript)|ensembl:ENST00000526148(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007507"(heart development)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008219"(cell death)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:P78344|rcsb pdb:3D3M|rcsb pdb:3L6A|rcsb pdb:4IUL|reactome:R-HSA-1169408|refseq:NP_001036024.3|refseq:NP_001166176.1|refseq:NP_001409.3|dip:DIP-31366N|uniprotkb:P78344(identity)|refseq:NM_001042559(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 254 nucleotides long and that maps to nucleotides 741 to 995 of the RefSeq entry NM_001042559.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:UIE1Um0s2KJ9hpaa9X6kfZ8enPc9606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:35D9F1BD717ABDD3|rigid:mIBvsfx3UvIMewBJLEljZCB3Dzk	false	sufficient binding region:?-?	sufficient binding region:209-342|sufficient binding region:36-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13129	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-958266|uniprotkb:Q14CQ1|uniprotkb:Q9NU60|ensembl:ENSP00000361857	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:rlf_human(display_long)|uniprotkb:RLF(gene name)|psi-mi:RLF(display_short)|uniprotkb:Rearranged L-myc fusion gene protein(gene name synonym)|uniprotkb:Zn-15-related protein(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6927924|imex:IM-21137-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036553.2|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSG00000117000(gene)|ensembl:ENST00000372771(transcript)|uniprotkb:Q13129(identity)|refseq:NM_012421(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 756 nucleotides long and that maps to nucleotides 34 to 790 of the RefSeq entry NM_012421.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:nWnF2P2Bh0uPJSAL6a5//1MxOl09606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:41E62AC93A1E4E1D|rigid:3SVKGqng34QaxoUE5WtjljXcC2M	false	sufficient binding region:?-?	sufficient binding region:1-570|sufficient binding region:532-570	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02749	uniprotkb:Q99IB8-PRO_0000045596	intact:EBI-2114682|uniprotkb:Q9UCN7|uniprotkb:B2R9M3|ensembl:ENSP00000205948	intact:EBI-6901449|intact:EBI-6927909	psi-mi:apoh_human(display_long)|uniprotkb:APOH(gene name)|psi-mi:APOH(display_short)|uniprotkb:B2G1(gene name synonym)|uniprotkb:Beta-2-glycoprotein I(gene name synonym)|uniprotkb:Apolipoprotein H(gene name synonym)|uniprotkb:Activated protein C-binding protein(gene name synonym)|uniprotkb:APC inhibitor(gene name synonym)|uniprotkb:Anticardiolipin cofactor(gene name synonym)	psi-mi:q99ib8-pro_0000045596(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6927905|imex:IM-21137-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000033.2|dip:DIP-46878N|ensembl:ENSG00000091583(gene)|ensembl:ENST00000205948(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007597"(blood coagulation, intrinsic pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042802"(identical protein binding)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051917"(regulation of fibrinolysis)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0060230"(lipoprotein lipase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR015104(Beta-2-glycoprotein-1 fifth domain)|interpro:IPR035976|mint:P02749|rcsb pdb:1C1Z|rcsb pdb:1G4F|rcsb pdb:1G4G|rcsb pdb:1QUB|rcsb pdb:2KRI|rcsb pdb:3OP8|rcsb pdb:4JHS|rcsb pdb:6V06|rcsb pdb:6V08|rcsb pdb:6V09|reactome:R-HSA-114608|uniprotkb:P02749(identity)|refseq:NM_000042(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045596(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:384|chain-seq-end:750	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 495 nucleotides long and that maps to nucleotides 379 to 874 of the RefSeq entry NM_000042.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:IcohvxbMLnnzWe0jmOC0/KVvP1Y9606	rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411	intact-crc:CC411D20D100781A|rigid:KP9RE6zCVf3j3BVSKZDJt6hijdM	false	sufficient binding region:?-?	sufficient binding region:264-338|sufficient binding region:1-234	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:P35222	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6927962|imex:IM-21137-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1|uniprotkb:P35222(identity)|refseq:NM_001098210(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 69 nucleotides long and that maps to nucleotides 1789 to 1858 of the RefSeq entry NM_001098210.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606	intact-crc:2353CDA4CEE2D91E|rigid:sw66aRkcWx+K85JXdIhRUW10Sc8	false	sufficient binding region:1-400	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99816	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-6858501|intact:EBI-6927943	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6927945|imex:IM-21137-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|uniprotkb:Q99816(identity)|refseq:NM_006292(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 597 nucleotides long and that maps to nucleotides 535 to 1132 of the RefSeq entry NM_006292.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:DA4E1350C568F033|rigid:9MGq8b+3b8MXKC/sX7rJj+y6/xU	false	sufficient binding region:?-?	sufficient binding region:1-200|sufficient binding region:135-631	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:P80303	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-2296670|uniprotkb:D3DQX5|uniprotkb:A8K642|uniprotkb:Q8NFT5|uniprotkb:V9HW75|ensembl:ENSP00000436455|ensembl:ENSP00000481959	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:nucb2_human(display_long)|uniprotkb:NUCB2(gene name)|psi-mi:NUCB2(display_short)|uniprotkb:NEFA(gene name synonym)|uniprotkb:DNA-binding protein NEFA(gene name synonym)|uniprotkb:Gastric cancer antigen Zg4(gene name synonym)|uniprotkb:Prepronesfatin(gene name synonym)|uniprotkb:Epididymis secretory protein Li 109(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6927977|imex:IM-21137-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	refseq:NP_005004.1|refseq:XP_016873295.1|refseq:XP_016873296.1|refseq:XP_016873297.1|refseq:XP_016873298.1|refseq:XP_016873299.1|refseq:XP_016873300.1|refseq:XP_016873301.1|refseq:XP_016873302.1|refseq:XP_016873303.1|refseq:XP_016873304.1|refseq:XP_016873305.1|refseq:XP_016873306.1|refseq:XP_016873307.1|refseq:XP_016873308.1|ensembl:ENSG00000070081(gene)|ensembl:ENST00000529010(transcript)|ensembl:ENST00000622082(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028813|go:"GO:0005886"(plasma membrane)|interpro:IPR040250|mint:P80303|uniprotkb:P80303(identity)|refseq:NM_005013(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 432 nucleotides long and that maps to nucleotides 1067 to 1499 of the RefSeq entry NM_005013.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2018/04/06	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:m5wJa0MtTVxrydwG9BXzjUMAlyc9606	intact-crc:FB123D1FD108BDE5|rigid:t72O3S1U5Tph12O9PqKJd0aMBek	false	sufficient binding region:367-531	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00584	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-2801658|uniprotkb:Q5T8Q0|uniprotkb:B2RDA7|uniprotkb:Q8TCU2|uniprotkb:Q9BZ46|uniprotkb:Q9BZ47|uniprotkb:E1P5C3|ensembl:ENSP00000422846|ensembl:ENSP00000426455	intact:EBI-6858501|intact:EBI-6927943	psi-mi:rnt2_human(display_long)|uniprotkb:RNASE6PL(gene name synonym)|uniprotkb:Ribonuclease 6(gene name synonym)|uniprotkb:RNASET2(gene name)|psi-mi:RNASET2(display_short)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928007|imex:IM-21137-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003721.2|ensembl:ENSG00000026297(gene)|ensembl:ENST00000476238(transcript)|ensembl:ENST00000508775(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0033897"(ribonuclease T2 activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001568(Ribonuclease T2)|interpro:IPR018188|interpro:IPR033130|interpro:IPR033697|interpro:IPR036430|rcsb pdb:3T0O|reactome:R-HSA-6798695|uniprotkb:O00584(identity)|refseq:NM_003730(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 303 nucleotides long and that maps to nucleotides 871 to 1174 of the RefSeq entry NM_003730.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:AQpSr9vTBzY3lb9OEdBWNW7gRok9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:8BCE3ADD9285CE1C|rigid:0mWLB88idq44NnoHFwl40juEYlo	false	sufficient binding region:?-?	sufficient binding region:1-200	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:Q13099	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-347427|uniprotkb:A2A491|uniprotkb:Q5SZJ6|uniprotkb:Q8N719|uniprotkb:B4DUS2|ensembl:ENSP00000261632	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:ift88_human(display_long)|uniprotkb:IFT88(gene name)|psi-mi:IFT88(display_short)|uniprotkb:TG737(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 10(gene name synonym)|uniprotkb:Recessive polycystic kidney disease protein Tg737 homolog(gene name synonym)|uniprotkb:TTC10(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928022|imex:IM-21137-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	refseq:NP_783195.2|refseq:XP_011533543.1|refseq:XP_016876247.1|refseq:NP_001305420.1|interpro:IPR019734|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-5610787|reactome:R-HSA-5620924|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0019894"(kinesin binding)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0031514"(motile cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR006597(Sel1-like)|ensembl:ENSG00000032742(gene)|ensembl:ENST00000351808(transcript)|go:"GO:0001822"(kidney development)|refseq:XP_005266610.1|refseq:NP_006522.2|refseq:XP_006719933.1|refseq:XP_011533544.1|refseq:XP_011533545.1|refseq:XP_016876246.1|uniprotkb:Q13099(identity)|refseq:NM_175605(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 489 nucleotides long and that maps to nucleotides 1641 to 2130 of the RefSeq entry NM_175605.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2020/08/14	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:kUeWmfrvdFuel6K1rJDf+5AtNAA9606	intact-crc:90D8CB918A52514B|rigid:ulM9kXOHyCtEF+/x+NBLxLvDgGI	false	sufficient binding region:209-342	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:Q99550	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-2511359|intact:EBI-2809473|ensembl:ENSP00000475489|uniprotkb:U3KQ28|uniprotkb:Q9H976|uniprotkb:A6NEE2|uniprotkb:A1L486|uniprotkb:B3KR87	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:mpp9_human(display_long)|uniprotkb:MPHOSPH9(gene name)|psi-mi:MPHOSPH9(display_short)|uniprotkb:MPP9(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928037|imex:IM-21137-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	ensembl:ENSG00000051825(gene)|ensembl:ENST00000606320(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0016020"(membrane)|interpro:IPR026636|refseq:XP_016874162.1|refseq:XP_016874168.1|refseq:XP_016874169.1|refseq:NP_073619.3|uniprotkb:Q99550(identity)|refseq:NM_022782(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 574 nucleotides long and that maps to nucleotides 1187 to 1761 of the RefSeq entry NM_022782.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:J1FkA3DERPWTHe57z9hMj6V52xI9606	intact-crc:887DC18DD4461F47|rigid:4VGR2OwyAFJ+D0KX8BgC6vcrjbU	false	sufficient binding region:36-213	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94880	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-2680164|uniprotkb:B4DI82|uniprotkb:A7MCZ3|ensembl:ENSP00000385795	intact:EBI-6858501|intact:EBI-6927943	psi-mi:phf14_human(display_long)|uniprotkb:KIAA0783(gene name synonym)|uniprotkb:PHF14(gene name)|psi-mi:PHF14(display_short)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6927992|imex:IM-21137-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055475.2|ensembl:ENSG00000106443(gene)|ensembl:ENST00000403050(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|mint:O94880|uniprotkb:O94880(identity)|refseq:NM_001007157(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 638 nucleotides long and that maps to nucleotides 2542 to 3180 of the RefSeq entry NM_001007157.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:5x6w7H9UP9mf4xk3lXYfAHaIo2Q9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:C5EBF8C0F05508B6|rigid:WLRDhU+WIfAlhN/Tu/aINdbUvcs	false	sufficient binding region:?-?	sufficient binding region:135-631	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P98175	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-721525|uniprotkb:Q14136|uniprotkb:C4AM81|uniprotkb:Q9BTE4|intact:EBI-1642096|intact:EBI-739959|uniprotkb:Q5JRR2|uniprotkb:Q9BTX0|uniprotkb:Q9NTB1|uniprotkb:A0A0A0MR66|ensembl:ENSP00000366829	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:rbm10_human(display_long)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928082|imex:IM-21137-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191395.1|refseq:NP_001191396.1|refseq:NP_005667.2|refseq:NP_690595.1|refseq:NP_001191397.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033095|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P98175|rcsb pdb:2LXI|rcsb pdb:2M2B|rcsb pdb:2MXV|rcsb pdb:2MXW|rcsb pdb:5ZSW|rcsb pdb:5ZSY|ensembl:ENSG00000182872(gene)|ensembl:ENST00000377604(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|uniprotkb:P98175(identity)|refseq:NM_152856(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 717 nucleotides long and that maps to nucleotides 826 to 1543 of the RefSeq entry NM_152856.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:LOhPGCjbvCh2MDG5JRHlrMrElW49606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:37E43C309172D553|rigid:1hIuJpHg6uVkt4dGAAgriZVV6XY	false	sufficient binding region:?-?	sufficient binding region:36-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27986	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-79464|intact:EBI-28974553|ensembl:ENSP00000428056|ensembl:ENSP00000429277|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928067|imex:IM-21137-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENST00000320694|ensembl:ENSP00000323512|ensembl:ENST00000336483|ensembl:ENSP00000338554|ensembl:ENSP00000428056|ensembl:ENSP00000429277|ensembl:ENST00000523872|ensembl:ENSP00000430098|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5SX9|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|reactome:R-HSA-1660499|rcsb pdb:7CIO|rcsb pdb:7LM2|reactome:R-HSA-180292|reactome:R-HSA-109704|reactome:R-HSA-1839117|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-1433557|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-5655291|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043559"(insulin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990578"(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:2V1Y|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|refseq:XP_016865074.1|refseq:XP_005248599.1|dip:DIP-119N|uniprotkb:P27986(identity)|refseq:NM_181523(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 810 nucleotides long and that maps to nucleotides 180 to 990 of the RefSeq entry NM_181523.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:A938EF28CA652B25|rigid:nyhHslrvseX3oS6eq3mnkFvWXRE	false	sufficient binding region:?-?	sufficient binding region:36-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15154	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928052|imex:IM-21137-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N|uniprotkb:Q15154(identity)|refseq:NM_006197(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 707 nucleotides long and that maps to nucleotides 4943 to 5650 of the RefSeq entry NM_006197.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2018/04/06	rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:C83C7CC91DE20B49|rigid:crDE0TOZOS5gOFniIkTlbD0sCBs	false	sufficient binding region:?-?	sufficient binding region:36-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UQ90	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-717201|uniprotkb:Q58F00|uniprotkb:O75756|uniprotkb:Q2TB70|uniprotkb:Q96IB0|ensembl:ENSP00000495795	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:spg7_human(display_long)|uniprotkb:Spastic paraplegia 7 protein(gene name synonym)|uniprotkb:SPG7(gene name)|psi-mi:SPG7(display_short)|uniprotkb:CAR(gene name synonym)|uniprotkb:PGN(gene name synonym)|uniprotkb:CMAR(gene name synonym)|uniprotkb:Cell matrix adhesion regulator(gene name synonym)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928097|imex:IM-21137-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003110.1|refseq:NP_955399.1|refseq:XP_016879088.1|ensembl:ENSG00000197912(gene)|ensembl:ENST00000645818(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005745"(m-AAA complex)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007399"(nervous system development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008233"(peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0042407"(cristae formation)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1902686"(mitochondrial outer membrane permeabilization involved in programmed cell death)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9UQ90|rcsb pdb:2QZ4|reactome:R-HSA-8949664|go:"GO:0005743"(mitochondrial inner membrane)|uniprotkb:Q9UQ90(identity)|refseq:NM_003119(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 380 nucleotides long and that maps to nucleotides 479 to 859 of the RefSeq entry NM_003119.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:mZ5/BJQnv0IF5nCFM17RzeklKDo9606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:D07A452B30DECFBA|rigid:zI8AcOBFXvhUOFZycZS3yZUtKpM	false	sufficient binding region:?-?	sufficient binding region:36-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NEF9	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-2824681|uniprotkb:Q5QFI2|uniprotkb:Q96AH4|uniprotkb:Q96DK2|ensembl:ENSP00000341324	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:srfb1_human(display_long)|uniprotkb:SRFBP1(gene name)|psi-mi:SRFBP1(display_short)|uniprotkb:SRF-dependent transcription regulation-associated protein(gene name synonym)|uniprotkb:p49/STRAP(gene name synonym)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928142|imex:IM-21137-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151304(gene)|ensembl:ENST00000339397(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR015158(Bud-site selection protein, BUD22)|interpro:IPR037393|refseq:NP_689759.2|uniprotkb:Q8NEF9(identity)|refseq:NM_152546(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 450 nucleotides long and that maps to nucleotides 336 to 786 of the RefSeq entry NM_152546.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:MQv9j4+l9h+7z05X/bRJAompesc9606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:0EA03FA1DBF3756E|rigid:3a/uEzM1bCGWvmCFf7e9ZPazOP4	false	sufficient binding region:?-?	sufficient binding region:36-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NEF9	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-2824681|uniprotkb:Q5QFI2|uniprotkb:Q96AH4|uniprotkb:Q96DK2|ensembl:ENSP00000341324	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:srfb1_human(display_long)|uniprotkb:SRFBP1(gene name)|psi-mi:SRFBP1(display_short)|uniprotkb:SRF-dependent transcription regulation-associated protein(gene name synonym)|uniprotkb:p49/STRAP(gene name synonym)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928127|imex:IM-21137-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151304(gene)|ensembl:ENST00000339397(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR015158(Bud-site selection protein, BUD22)|interpro:IPR037393|refseq:NP_689759.2|uniprotkb:Q8NEF9(identity)|refseq:NM_152546(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 424 nucleotides long and that maps to nucleotides 210 to 634 of the RefSeq entry NM_152546.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:MQv9j4+l9h+7z05X/bRJAompesc9606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:C6752419DF983A08|rigid:3a/uEzM1bCGWvmCFf7e9ZPazOP4	false	sufficient binding region:?-?	sufficient binding region:356-466	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13813	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928112|imex:IM-21137-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N|uniprotkb:Q13813(identity)|refseq:NM_003127(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 693 nucleotides long and that maps to nucleotides 1360 to 2053 of the RefSeq entry NM_003127.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:D007BB7872EC883B|rigid:9HAiuyskc70HgBo8hklN2jN8u04	false	sufficient binding region:?-?	sufficient binding region:36-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:Q9H8Y8	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-739467|uniprotkb:Q96I74|uniprotkb:Q96K84|uniprotkb:Q9H946|uniprotkb:Q9UFW4|uniprotkb:Q53TE3|intact:EBI-28970723|uniprotkb:B4DKT0|ensembl:ENSP00000234160	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:gors2_human(display_long)|uniprotkb:GORASP2(gene name)|psi-mi:GORASP2(display_short)|uniprotkb:Golgi reassembly-stacking protein of 55 kDa(gene name synonym)|uniprotkb:p59(gene name synonym)|uniprotkb:Golgi phosphoprotein 6(gene name synonym)|uniprotkb:GOLPH6(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928157|imex:IM-21137-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	ensembl:ENSP00000234160|refseq:NP_001188357.1|refseq:NP_056345.3|refseq:XP_006712471.1|ensembl:ENSG00000115806(gene)|ensembl:ENST00000234160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006996"(organelle organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070925"(organelle assembly)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|mint:Q9H8Y8|rcsb pdb:3RLE|rcsb pdb:4EDJ|reactome:R-HSA-162658|uniprotkb:Q9H8Y8(identity)|refseq:NM_015530(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 468 nucleotides long and that maps to nucleotides 95 to 563 of the RefSeq entry NM_015530.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:xSy3HsObmteg/doer5eLoZiz+fU9606	intact-crc:23CF73B0A7F7B87E|rigid:j6aeMavhlahl5cEThC0j0z366zc	false	sufficient binding region:36-213	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13137	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928172|imex:IM-21137-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N|uniprotkb:Q13137(identity)|refseq:NM_005831(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	psi-mi:"MI:0469"(intact)	crc64:609B121DA1A9DCB8	chain-seq-start:2443|chain-seq-end:3033	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 746 nucleotides long and that maps to nucleotides 399 to 1145 of the RefSeq entry NM_005831.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:C36E0EF0D9BED209|rigid:wlMeKO1qyD5SLc0QzU+huyYum/8	false	sufficient binding region:?-?	sufficient binding region:1-400	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:Q08379	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928187|imex:IM-21137-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|uniprotkb:Q08379(identity)|refseq:NM_004486(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 881 nucleotides long and that maps to nucleotides 1000 to 1881 of the RefSeq entry NM_004486.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	intact-crc:8C9A0D64858CD402|rigid:hbPIHfmPm4GTfbLeY2c8A8FgqWg	false	sufficient binding region:36-213	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q14999	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-308606|uniprotkb:Q5T654|ensembl:ENSP00000265348|uniprotkb:B4DYZ0|uniprotkb:F5H0L1	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:cul7_human(display_long)|uniprotkb:CUL7(gene name)|psi-mi:CUL7(display_short)|uniprotkb:KIAA0076(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928202|imex:IM-21137-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	ensembl:ENSG00000044090(gene)|ensembl:ENST00000265348(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001890"(placenta development)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990393"(3M complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR021097|interpro:IPR031223|interpro:IPR036317|interpro:IPR036388|mint:Q14999|rcsb pdb:2JNG|reactome:R-HSA-381038|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001161842.1|refseq:NP_055595.2|dip:DIP-31618N|dip:DIP-60187N|uniprotkb:Q14999(identity)|refseq:NM_014780(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 138 nucleotides long and that maps to nucleotides 1036 to 1174 of the RefSeq entry NM_014780.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:8sODZSppCsuEgRmhSHp3UjwOf2M9606	intact-crc:AE84EDE6F7B41E8A|rigid:79ROUNBvDqdNn8pWZaE32b6FcI8	false	sufficient binding region:1-400	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02675	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-1034445|uniprotkb:A0JLR9|uniprotkb:Q32Q65|uniprotkb:Q3KPF2|uniprotkb:B2R7G3|ensembl:ENSP00000306099	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:fibb_human(display_long)|uniprotkb:FGB(gene name)|psi-mi:FGB(display_short)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928247|imex:IM-21137-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171670.1|refseq:NP_005132.2|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:P02675|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|ensembl:ENSG00000171564(gene)|ensembl:ENST00000302068(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|reactome:R-HSA-6802948|dip:DIP-385N|uniprotkb:P02675(identity)|refseq:NM_005141(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 843 nucleotides long and that maps to nucleotides 106 to 949 of the RefSeq entry NM_005141.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:cbcOBnZB/W/Y7eE/IxM2HfZHpK49606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:A76A0ABEB99FDDE6|rigid:SRiI+t/kQeNQjHnX0D3B4JTKpyo	false	sufficient binding region:?-?	sufficient binding region:532-570	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P78344	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-296519|uniprotkb:O60877|uniprotkb:P78404|uniprotkb:Q0VH00|uniprotkb:Q53EU1|uniprotkb:Q58EZ2|uniprotkb:Q8NI71|uniprotkb:Q96C16|ensembl:ENSP00000340281|ensembl:ENSP00000433371|ensembl:ENSP00000433664|uniprotkb:Q0VH01|uniprotkb:Q2NKW9|uniprotkb:Q49A79	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:if4g2_human(display_long)|uniprotkb:EIF4G2(gene name)|psi-mi:EIF4G2(display_short)|uniprotkb:DAP5(gene name synonym)|uniprotkb:OK/SW-cl.75(orf name)|uniprotkb:p97(gene name synonym)|uniprotkb:Death-associated protein 5(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928232|imex:IM-21137-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110321(gene)|ensembl:ENST00000339995(transcript)|ensembl:ENST00000525681(transcript)|ensembl:ENST00000526148(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007507"(heart development)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008219"(cell death)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:P78344|rcsb pdb:3D3M|rcsb pdb:3L6A|rcsb pdb:4IUL|reactome:R-HSA-1169408|refseq:NP_001036024.3|refseq:NP_001166176.1|refseq:NP_001409.3|dip:DIP-31366N|uniprotkb:P78344(identity)|refseq:NM_001042559(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 254 nucleotides long and that maps to nucleotides 741 to 995 of the RefSeq entry NM_001042559.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:UIE1Um0s2KJ9hpaa9X6kfZ8enPc9606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:1055FBB8CA997375|rigid:EozDZdrElyulEhnU9cfGIGM5Kk8	false	sufficient binding region:?-?	sufficient binding region:532-570	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03001	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928217|imex:IM-21137-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N|uniprotkb:Q03001(identity)|refseq:NM_015548(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 757 nucleotides long and that maps to nucleotides 13305 to 14062 of the RefSeq entry NM_015548.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:088C2184CE440F89|rigid:e8ULu3y/bloD8vR6SG05u61Lm0U	false	sufficient binding region:?-?	sufficient binding region:1-400	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08379	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928277|imex:IM-21137-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N|uniprotkb:Q08379(identity)|refseq:NM_004486(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 648 nucleotides long and that maps to nucleotides 1304 to 1952 of the RefSeq entry NM_004486.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:1C12DD72460396C8|rigid:K3gs8ME7DyIvxNNyGj1kMeYzoH4	false	sufficient binding region:?-?	sufficient binding region:1-400	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q9H8Y8	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-739467|uniprotkb:Q96I74|uniprotkb:Q96K84|uniprotkb:Q9H946|uniprotkb:Q9UFW4|uniprotkb:Q53TE3|intact:EBI-28970723|uniprotkb:B4DKT0|ensembl:ENSP00000234160	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:gors2_human(display_long)|uniprotkb:GORASP2(gene name)|psi-mi:GORASP2(display_short)|uniprotkb:Golgi reassembly-stacking protein of 55 kDa(gene name synonym)|uniprotkb:p59(gene name synonym)|uniprotkb:Golgi phosphoprotein 6(gene name synonym)|uniprotkb:GOLPH6(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928292|imex:IM-21137-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	ensembl:ENSP00000234160|refseq:NP_001188357.1|refseq:NP_056345.3|refseq:XP_006712471.1|ensembl:ENSG00000115806(gene)|ensembl:ENST00000234160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006996"(organelle organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070925"(organelle assembly)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|mint:Q9H8Y8|rcsb pdb:3RLE|rcsb pdb:4EDJ|reactome:R-HSA-162658|uniprotkb:Q9H8Y8(identity)|refseq:NM_015530(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 468 nucleotides long and that maps to nucleotides 95 to 563 of the RefSeq entry NM_015530.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:xSy3HsObmteg/doer5eLoZiz+fU9606	intact-crc:93A6C6BD6B3AFCB7|rigid:aJaIbbAxr6pPv+LVb8SSluk9i6w	false	sufficient binding region:1-400	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02751	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928262|imex:IM-21137-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|uniprotkb:P02751(identity)|refseq:NM_212476(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 599 nucleotides long and that maps to nucleotides 6371 to 6970 of the RefSeq entry NM_212476.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2019/10/18	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:943B925D621A81DA|rigid:3OgtViexC/CTBTXQ3v24iYte1bQ	false	sufficient binding region:?-?	sufficient binding region:1-400	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:P11142	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928330|imex:IM-21137-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N|uniprotkb:P11142(identity)|refseq:NM_006597(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 548 nucleotides long and that maps to nucleotides 1074 to 1622 of the RefSeq entry NM_006597.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:DE4967467BFA6640|rigid:IGoO1qAdT9LSi+304NTllofVsY4	false	sufficient binding region:1-400	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q9BXC0	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-6928311|ensembl:ENSP00000389255|uniprotkb:B2R9X4|uniprotkb:Q6NXU5|uniprotkb:Q3Y5J3|uniprotkb:Q4VBN1	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:hcar1_human(display_long)|uniprotkb:G-protein coupled receptor 104(gene name synonym)|uniprotkb:G-protein coupled receptor 81(gene name synonym)|uniprotkb:GPR104(gene name synonym)|uniprotkb:GPR81(gene name synonym)|uniprotkb:HCA1(gene name synonym)|uniprotkb:FKSG80(orf name)|uniprotkb:HCAR1(gene name)|psi-mi:HCAR1(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928307|imex:IM-21137-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	ensembl:ENSG00000196917(gene)|ensembl:ENST00000432564(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR028016|reactome:R-HSA-3296197|reactome:R-HSA-418594|refseq:NP_115943.1|uniprotkb:Q9BXC0(identity)|refseq:NM_032554(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 117 nucleotides long and that maps to nucleotides 1619 to 1736 of the RefSeq entry NM_032554.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:857B0GGbArS9rGfB4iAHu+3NhIE9606	intact-crc:7A78903F90EFDB60|rigid:kHEExXJP2ba5LAA5Qq0G7Gk4PgI	false	sufficient binding region:367-531	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:O75592	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928360|imex:IM-21137-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	refseq:NP_055872.4|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003646(Bacterial SH3-like region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|ensembl:ENSG00000005810(gene)|ensembl:ENST00000544440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|dip:DIP-28142N|uniprotkb:O75592(identity)|refseq:NM_015057(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 673 nucleotides long and that maps to nucleotides 2089 to 2762 of the RefSeq entry NM_015057.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2018/07/05	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	intact-crc:8C57699B9A5D3F66|rigid:Hk5Nf0lkzgyVbyjXsSsR9jUS2tM	false	sufficient binding region:1-400	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q86UP2	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|ensembl:ENSP00000378725|ensembl:ENSP00000432149|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928345|imex:IM-21137-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	refseq:NP_001072989.1|refseq:NP_004977.2|ensembl:ENSG00000126777(gene)|ensembl:ENST00000395314(transcript)|ensembl:ENST00000459737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|refseq:XP_011535053.1|refseq:XP_011535055.1|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N|uniprotkb:Q86UP2(identity)|refseq:NM_182926(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 641 nucleotides long and that maps to nucleotides 2543 to 3184 of the RefSeq entry NM_182926.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606	intact-crc:3F2552233A8D8A28|rigid:/ehLGjnDJ3Bvn0HCXKNQpSvOWps	false	sufficient binding region:367-531	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22307	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-1050999|uniprotkb:Q15432|uniprotkb:Q16622|uniprotkb:Q99430|uniprotkb:Q5VVZ1|uniprotkb:D3DQ37|ensembl:ENSP00000360569|uniprotkb:Q6NXF4|uniprotkb:B4DHP6|uniprotkb:A6NM69|uniprotkb:B4DGJ9|uniprotkb:C9JC79|uniprotkb:E1B6W5|uniprotkb:F2Z3J1	intact:EBI-6858501|intact:EBI-6927943	psi-mi:scp2_human(display_long)|uniprotkb:Propanoyl-CoA C-acyltransferase(gene name synonym)|uniprotkb:Sterol carrier protein X(gene name synonym)|uniprotkb:SCP-chi(gene name synonym)|uniprotkb:SCPX(gene name synonym)|uniprotkb:SCP2(gene name)|psi-mi:SCP2(display_short)|uniprotkb:Acetyl-CoA C-myristoyltransferase(gene name synonym)|uniprotkb:Non-specific lipid-transfer protein(gene name synonym)|uniprotkb:SCP-2/3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:SCP-2/thiolase(gene name synonym)|uniprotkb:Straight-chain acyl-CoA oxidase(gene name synonym)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928375|imex:IM-21137-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180528.1|refseq:NP_001007100.1|refseq:NP_001007101.1|refseq:NP_001007251.1|refseq:NP_002970.2|ensembl:ENSG00000116171(gene)|ensembl:ENST00000371514(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006701"(progesterone biosynthetic process)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032385"(positive regulation of intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0032959"(inositol trisphosphate biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0033814"(propanoyl-CoA C-acyltransferase activity)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045940"(positive regulation of steroid metabolic process)|go:"GO:0050632"(propionyl-CoA C2-trimethyltridecanoyltransferase activity)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|go:"GO:0070538"(oleic acid binding)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0120019"(phosphatidylcholine transfer activity)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1901373"(lipid hydroperoxide transport)|interpro:IPR003033(Sterol-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|interpro:IPR036527|mint:P22307|rcsb pdb:1QND|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-9033241|reactome:R-HSA-9033500|rcsb pdb:2C0L|refseq:XP_016857535.1|refseq:NP_001007099.1|refseq:NP_001180546.1|uniprotkb:P22307(identity)|refseq:NM_002979(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 372 nucleotides long and that maps to nucleotides 149 to 521 of the RefSeq entry NM_002979.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:Vwnu7RuD/2qhcH55Fl9v2TMErtc9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:FD72B7ABF8ED0C33|rigid:RZa+Cmp1qx4+8RZsmcGJxIfh77M	false	sufficient binding region:?-?	sufficient binding region:135-631	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99816	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928390|imex:IM-21137-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|uniprotkb:Q99816(identity)|refseq:NM_006292(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 597 nucleotides long and that maps to nucleotides 535 to 1132 of the RefSeq entry NM_006292.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:1F90806883FFE09D|rigid:0HjXiWiCmkY7e5FHsRAgylt0oQg	false	sufficient binding region:?-?	sufficient binding region:356-466|sufficient binding region:36-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:Q9ULJ7	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-5653671|uniprotkb:Q6N064|uniprotkb:A8K4V3|uniprotkb:Q6ZSE6|uniprotkb:B4DHJ6|uniprotkb:E9PDW0|ensembl:ENSP00000425658	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:anr50_human(display_long)|uniprotkb:KIAA1223(gene name synonym)|uniprotkb:ANKRD50(gene name)|psi-mi:ANKRD50(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928407|imex:IM-21137-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	dip:DIP-47302N|refseq:NP_001161354.1|refseq:NP_065070.1|refseq:XP_016863960.1|ensembl:ENSG00000151458(gene)|ensembl:ENST00000504087(transcript)|go:"GO:0005768"(endosome)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q9ULJ7|uniprotkb:Q9ULJ7(identity)|refseq:NM_020337(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 160 nucleotides long and that maps to nucleotides 1903 to 2063 of the RefSeq entry NM_020337.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:cP1xkkSlKwersPLj/gvrnWOjm+89606	intact-crc:6361FD39B281DF57|rigid:YgRBaW02BG717XWQpjnELfNe6pk	false	sufficient binding region:36-213	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86SQ7	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-1047850|uniprotkb:Q3ZCR6|uniprotkb:Q8N5F2|uniprotkb:Q9P0F1|uniprotkb:O60527|ensembl:ENSP00000355499|ensembl:ENSP00000483550	intact:EBI-6858501|intact:EBI-6927943	psi-mi:sdcg8_human(display_long)|uniprotkb:Antigen NY-CO-8(gene name synonym)|uniprotkb:Centrosomal colon cancer autoantigen protein(gene name synonym)|uniprotkb:SDCCAG8(gene name)|psi-mi:SDCCAG8(display_short)|uniprotkb:CCCAP(gene name synonym)|uniprotkb:NPHP10(gene name synonym)|uniprotkb:HSPC085(orf name)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928422|imex:IM-21137-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006633.1|ensembl:ENSG00000054282(gene)|ensembl:ENSG00000276111(gene)|ensembl:ENST00000366541(transcript)|ensembl:ENST00000622598(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035148"(tube formation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0097733"(photoreceptor cell cilium)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR031887|mint:Q86SQ7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273080.1|uniprotkb:Q86SQ7(identity)|refseq:NM_006642(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 338 nucleotides long and that maps to nucleotides 1939 to 2277 of the RefSeq entry NM_006642.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:Z3ynDtbmAV7usLzKH+M3Ilf6Ebw9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:94F347E35048D7F7|rigid:SYVjflrlZMr46q/VS1jwwlqkVVg	false	sufficient binding region:?-?	sufficient binding region:135-631	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14BN4	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681	intact:EBI-6858501|intact:EBI-6927943	psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928465|imex:IM-21137-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1|uniprotkb:Q14BN4(identity)|refseq:NM_007159(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 627 nucleotides long and that maps to nucleotides 1567 to 2194 of the RefSeq entry NM_007159.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:0810F1DB6EB11C70|rigid:sUI4nf6PtuhQb5Erv8ve7oPK2Cs	false	sufficient binding region:?-?	sufficient binding region:135-631	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P05546	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-1221005|uniprotkb:Q6IBZ5|uniprotkb:D3DX34|uniprotkb:B2RAI1|ensembl:ENSP00000215727|ensembl:ENSP00000384050	intact:EBI-6858501|intact:EBI-6927943	psi-mi:hep2_human(display_long)|uniprotkb:SERPIND1(gene name)|psi-mi:SERPIND1(display_short)|uniprotkb:HCF2(gene name synonym)|uniprotkb:Heparin cofactor II(gene name synonym)|uniprotkb:Protease inhibitor leuserpin-2(gene name synonym)|uniprotkb:Serpin D1(gene name synonym)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928437|imex:IM-21137-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000176.2|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006935"(chemotaxis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033831|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1JMJ|rcsb pdb:1JMO|rcsb pdb:2NAT|rcsb pdb:2NCU|rcsb pdb:2NCV|rcsb pdb:2NCW|rcsb pdb:6J12|rcsb pdb:6KBO|rcsb pdb:6KBV|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-381426|reactome:R-HSA-8957275|ensembl:ENSG00000099937(gene)|ensembl:ENST00000215727(transcript)|ensembl:ENST00000406799(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|uniprotkb:P05546(identity)|refseq:NM_000185(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 467 nucleotides long and that maps to nucleotides 122 to 589 of the RefSeq entry NM_000185.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:lG/XASWu25/oH77pIGXK4quoqeU9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:B693FB9F117E9EDB|rigid:i9IjtFT3gr47OQ+bWSiiHJvbyBA	false	sufficient binding region:?-?	sufficient binding region:1-200	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:Q86VW0	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-6117072|uniprotkb:Q53R38|uniprotkb:Q53SP3|uniprotkb:Q5GM69|uniprotkb:Q8N6M1|uniprotkb:Q96LQ2|ensembl:ENSP00000415332	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:sesd1_human(display_long)|uniprotkb:SESTD1(gene name)|psi-mi:SESTD1(display_short)|uniprotkb:SOLO(gene name synonym)|uniprotkb:Huntingtin-interacting protein-like protein(gene name synonym)|uniprotkb:Protein Solo(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928452|imex:IM-21137-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	refseq:XP_011510441.1|refseq:NP_835224.3|ensembl:ENSG00000187231(gene)|ensembl:ENST00000428443(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|uniprotkb:Q86VW0(identity)|refseq:NM_178123(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 421 nucleotides long and that maps to nucleotides 474 to 895 of the RefSeq entry NM_178123.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:GS9Hqrsyep/iL7L8gQwOJhX95IY9606	intact-crc:46BF1583F11443D3|rigid:Em/yGJoZWIZKlczcsor1b5XzyPI	false	-	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02787	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-714319|uniprotkb:O43890|uniprotkb:Q9NQB8|uniprotkb:Q9UHV0|uniprotkb:Q1HBA5|ensembl:ENSP00000385834	intact:EBI-6858501|intact:EBI-6927943	psi-mi:trfe_human(display_long)|uniprotkb:Siderophilin(gene name synonym)|uniprotkb:Beta-1 metal-binding globulin(gene name synonym)|uniprotkb:TF(gene name)|psi-mi:TF(display_short)|uniprotkb:PRO1400(orf name)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928495|imex:IM-21137-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001054.1|rcsb pdb:1JQF|rcsb pdb:1N7W|rcsb pdb:1N7X|rcsb pdb:1N84|rcsb pdb:1OQG|rcsb pdb:1OQH|rcsb pdb:1RYO|rcsb pdb:1SUV|rcsb pdb:2HAU|rcsb pdb:2HAV|rcsb pdb:2O7U|rcsb pdb:2O84|rcsb pdb:3FGS|rcsb pdb:3QYT|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:1FQF|rcsb pdb:3S9N|rcsb pdb:3SKP|rcsb pdb:3V83|rcsb pdb:3V89|rcsb pdb:3V8X|rcsb pdb:4H0W|rcsb pdb:4X1B|rcsb pdb:4X1D|rcsb pdb:5DYH|rcsb pdb:5H52|rcsb pdb:5WTD|rcsb pdb:5X5P|rcsb pdb:5Y6K|rcsb pdb:6CTC|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:3VE1|rcsb pdb:6JAS|rcsb pdb:6SOY|rcsb pdb:6SOZ|rcsb pdb:6UJ6|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8957275|reactome:R-HSA-917937|reactome:R-HSA-917977|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045178"(basal part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0072562"(blood microparticle)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030685|mint:P02787|rcsb pdb:1A8E|go:"GO:0034774"(secretory granule lumen)|rcsb pdb:1A8F|rcsb pdb:1B3E|rcsb pdb:1BP5|rcsb pdb:1BTJ|rcsb pdb:1D3K|rcsb pdb:1D4N|rcsb pdb:1DTG|rcsb pdb:1FQE|ensembl:ENSG00000091513(gene)|ensembl:ENST00000402696(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031982"(vesicle)|go:"GO:0034756"(regulation of iron ion transport)|refseq:XP_016862578.1|refseq:XP_016862579.1|dip:DIP-2738N|uniprotkb:P02787(identity)|refseq:NM_001063(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 246 nucleotides long and that maps to nucleotides 1749 to 1995 of the RefSeq entry NM_001063.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:CN9nME9TVV6/FGrhH6XHtJF9/HI9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:5193A03E8E4AA79D|rigid:/L9eqTK5GczephiLPDAy3vUk7wc	false	sufficient binding region:?-?	sufficient binding region:1-200	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NQB0	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	intact:EBI-6858501|intact:EBI-6927943	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928480|imex:IM-21137-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430|uniprotkb:Q9NQB0(identity)|refseq:NM_030756(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 278 nucleotides long and that maps to nucleotides 408 to 686 of the RefSeq entry NM_030756.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:CDA39D38F07B5560|rigid:qOWIuPE6IzdYO+pc4nqDvnK8dqM	false	sufficient binding region:?-?	sufficient binding region:1-200	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:P02787	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-714319|uniprotkb:O43890|uniprotkb:Q9NQB8|uniprotkb:Q9UHV0|uniprotkb:Q1HBA5|ensembl:ENSP00000385834	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:trfe_human(display_long)|uniprotkb:Siderophilin(gene name synonym)|uniprotkb:Beta-1 metal-binding globulin(gene name synonym)|uniprotkb:TF(gene name)|psi-mi:TF(display_short)|uniprotkb:PRO1400(orf name)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928510|imex:IM-21137-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	refseq:NP_001054.1|rcsb pdb:1JQF|rcsb pdb:1N7W|rcsb pdb:1N7X|rcsb pdb:1N84|rcsb pdb:1OQG|rcsb pdb:1OQH|rcsb pdb:1RYO|rcsb pdb:1SUV|rcsb pdb:2HAU|rcsb pdb:2HAV|rcsb pdb:2O7U|rcsb pdb:2O84|rcsb pdb:3FGS|rcsb pdb:3QYT|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:1FQF|rcsb pdb:3S9N|rcsb pdb:3SKP|rcsb pdb:3V83|rcsb pdb:3V89|rcsb pdb:3V8X|rcsb pdb:4H0W|rcsb pdb:4X1B|rcsb pdb:4X1D|rcsb pdb:5DYH|rcsb pdb:5H52|rcsb pdb:5WTD|rcsb pdb:5X5P|rcsb pdb:5Y6K|rcsb pdb:6CTC|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:3VE1|rcsb pdb:6JAS|rcsb pdb:6SOY|rcsb pdb:6SOZ|rcsb pdb:6UJ6|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8957275|reactome:R-HSA-917937|reactome:R-HSA-917977|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045178"(basal part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0072562"(blood microparticle)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030685|mint:P02787|rcsb pdb:1A8E|go:"GO:0034774"(secretory granule lumen)|rcsb pdb:1A8F|rcsb pdb:1B3E|rcsb pdb:1BP5|rcsb pdb:1BTJ|rcsb pdb:1D3K|rcsb pdb:1D4N|rcsb pdb:1DTG|rcsb pdb:1FQE|ensembl:ENSG00000091513(gene)|ensembl:ENST00000402696(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031982"(vesicle)|go:"GO:0034756"(regulation of iron ion transport)|refseq:XP_016862578.1|refseq:XP_016862579.1|dip:DIP-2738N|uniprotkb:P02787(identity)|refseq:NM_001063(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 62 nucleotides long and that maps to nucleotides 1749 to 1811 of the RefSeq entry NM_001063.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:CN9nME9TVV6/FGrhH6XHtJF9/HI9606	intact-crc:DA29F62EFE949D2B|rigid:/L9eqTK5GczephiLPDAy3vUk7wc	false	sufficient binding region:135-631	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:P67936	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-1642100|uniprotkb:P07226|uniprotkb:Q15659|uniprotkb:Q9BU85|uniprotkb:Q9H8Q3|uniprotkb:Q5U0D9|uniprotkb:Q9UCS1|uniprotkb:Q9UCS2|uniprotkb:Q9UCS3|uniprotkb:Q9UCS4|ensembl:ENSP00000495347	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:tpm4_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym)|uniprotkb:TM30p1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928525|imex:IM-21137-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	refseq:NP_001138632.1|refseq:NP_003281.1|ensembl:ENSG00000167460(gene)|ensembl:ENST00000643579(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|mint:P67936|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|uniprotkb:P67936(identity)|refseq:NM_003290(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 456 nucleotides long and that maps to nucleotides 242 to 698 of the RefSeq entry NM_003290.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:o8bLltMHW3vvC7Tp6YpiC0M6lkw9606	intact-crc:855BC18FC6BC82D8|rigid:2n/CxRmJTF4h70kuVffhf5nW0yU	false	sufficient binding region:135-631	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:O14628	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-4395540|uniprotkb:A8K234|uniprotkb:B3KTK2|uniprotkb:B4DEL0|uniprotkb:Q0VAJ6|uniprotkb:Q658N8|uniprotkb:Q6ZNA9|uniprotkb:C9JLY9|uniprotkb:L7MNK2|ensembl:ENSP00000382511	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:zn195_human(display_long)|uniprotkb:ZNF195(gene name)|psi-mi:ZNF195(display_short)|uniprotkb:ZNFP104(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928540|imex:IM-21137-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	refseq:NP_001123991.1|refseq:NP_001123992.1|refseq:NP_001229770.1|refseq:NP_001229771.1|refseq:NP_009083.2|refseq:NP_001229772.1|refseq:XP_016873752.1|refseq:NP_001243754.1|refseq:NP_001243752.1|refseq:NP_001243753.1|ensembl:ENSG00000005801(gene)|ensembl:ENST00000399602(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|uniprotkb:O14628(identity)|refseq:NM_007152(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 611 nucleotides long and that maps to nucleotides 648 to 1259 of the RefSeq entry NM_007152.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:L28vWHahr3yXs1aXKhaHk2vsuFc9606	intact-crc:DCD6C7CFF14312C1|rigid:brTwpwHA4A7UdgJ4la8tfqpL4Ys	false	sufficient binding region:135-631	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:Q14966	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-742207|uniprotkb:B5MDV1|uniprotkb:Q53R34|uniprotkb:Q5XJ05|uniprotkb:Q68DP3|uniprotkb:Q6P2H2|uniprotkb:Q7Z3T7|uniprotkb:Q8NF92|uniprotkb:Q8TCA1|uniprotkb:Q9H2G1|uniprotkb:Q9NP37|uniprotkb:B7ZLD1|ensembl:ENSP00000264447|ensembl:ENSP00000386433|uniprotkb:A0A096LPH6	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:zn638_human(display_long)|uniprotkb:ZNF638(gene name)|psi-mi:ZNF638(display_short)|uniprotkb:NP220(gene name synonym)|uniprotkb:ZFML(gene name synonym)|uniprotkb:Zinc finger matrin-like protein(gene name synonym)|uniprotkb:Nuclear protein 220(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se33-1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928555|imex:IM-21137-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	refseq:NP_001014972.1|refseq:NP_055312.2|refseq:NP_001239541.1|refseq:NP_001239542.1|ensembl:ENSG00000075292(gene)|ensembl:ENST00000264447(transcript)|ensembl:ENST00000409544(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR033096|interpro:IPR035979|interpro:IPR036236|mint:Q14966|rcsb pdb:6SXW|reactome:R-HSA-381340|go:"GO:0003690"(double-stranded DNA binding)|ensembl:ENSP00000264447|ensembl:ENSP00000386433|ensembl:ENST00000410075|ensembl:ENSP00000485608|dip:DIP-42386N|uniprotkb:Q14966(identity)|refseq:NM_001014972(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 704 nucleotides long and that maps to nucleotides 5421 to 6125 of the RefSeq entry NM_001014972.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:KkoO3Hgmx9CwI4LgVmk2ankakIY9606	intact-crc:2D17867BD3E71BF6|rigid:h5yriiFN1PXgTDunHFyw9wURWKY	false	sufficient binding region:135-631	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:P04035	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-465513|uniprotkb:B7Z3Y9|uniprotkb:Q8N190|ensembl:ENSP00000287936|ensembl:ENSP00000426745|ensembl:ENSP00000505561|ensembl:ENSP00000505805|ensembl:ENSP00000506232	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:hmdh_human(display_long)|uniprotkb:HMGCR(gene name)|psi-mi:HMGCR(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928587|imex:IM-21137-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	refseq:NP_000850.1|refseq:NP_001124468.1|refseq:XP_011541659.1|refseq:XP_011541660.1|ensembl:ENSG00000113161(gene)|ensembl:ENST00000287936(transcript)|ensembl:ENST00000511206(transcript)|ensembl:ENST00000680940(transcript)|ensembl:ENST00000681271(transcript)|ensembl:ENST00000681410(transcript)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0006743"(ubiquinone metabolic process)|go:"GO:0007568"(aging)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070402"(NADPH binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR004816(Hydroxymethylglutaryl-CoA reductase, class I, metazoan)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|rcsb pdb:1DQ8|rcsb pdb:1DQ9|rcsb pdb:1DQA|rcsb pdb:1HW8|rcsb pdb:1HW9|rcsb pdb:1HWI|rcsb pdb:1HWJ|rcsb pdb:1HWK|rcsb pdb:1HWL|rcsb pdb:2Q1L|rcsb pdb:2Q6B|rcsb pdb:2Q6C|rcsb pdb:2R4F|rcsb pdb:3BGL|rcsb pdb:3CCT|rcsb pdb:3CCW|rcsb pdb:3CCZ|rcsb pdb:3CD0|rcsb pdb:3CD5|rcsb pdb:3CD7|rcsb pdb:3CDA|rcsb pdb:3CDB|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-9619665|uniprotkb:P04035(identity)|refseq:NM_000859(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 663 nucleotides long and that maps to nucleotides 1673 to 2336 of the RefSeq entry NM_000859.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:fXmkDPv7ThH/PSLiNUgYR6hiIpY9606	intact-crc:5FFD347661C28E4E|rigid:kUT5daM9CxRgi/iU8f4RuZ9mKhM	false	sufficient binding region:36-213	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01024	uniprotkb:Q99IB8-PRO_0000045601	intact:EBI-905851|uniprotkb:A7E236|ensembl:ENSP00000245907	intact:EBI-6928570|intact:EBI-8786387	psi-mi:co3_human(display_long)|uniprotkb:C3(gene name)|psi-mi:C3(display_short)|uniprotkb:CPAMD1(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1(gene name synonym)	psi-mi:q99ib8-pro_0000045601(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928572|imex:IM-21137-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000055.2|dip:DIP-35180N|ensembl:ENSG00000125730(gene)|ensembl:ENST00000245907(transcript)|go:"GO:0001798"(positive regulation of type IIa hypersensitivity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001970"(positive regulation of activation of membrane attack complex)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006956"(complement activation)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0016322"(neuron remodeling)|go:"GO:0031715"(C5L2 anaphylatoxin chemotactic receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035846"(oviduct epithelium development)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1905114"(cell surface receptor signaling pathway involved in cell-cell signaling)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR035711|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|mint:P01024|rcsb pdb:1C3D|rcsb pdb:1GHQ|rcsb pdb:1W2S|rcsb pdb:2A73|rcsb pdb:2A74|rcsb pdb:2GOX|rcsb pdb:2I07|rcsb pdb:2ICE|rcsb pdb:2ICF|rcsb pdb:2NOJ|rcsb pdb:2QKI|rcsb pdb:2WII|rcsb pdb:2WIN|rcsb pdb:2WY7|rcsb pdb:2WY8|rcsb pdb:2XQW|rcsb pdb:2XWB|rcsb pdb:2XWJ|rcsb pdb:3D5R|rcsb pdb:3D5S|rcsb pdb:3G6J|rcsb pdb:3L3O|rcsb pdb:3L5N|rcsb pdb:3NMS|rcsb pdb:3OED|rcsb pdb:3OHX|rcsb pdb:3OXU|rcsb pdb:3RJ3|rcsb pdb:3T4A|rcsb pdb:4HW5|rcsb pdb:4HWJ|rcsb pdb:4I6O|rcsb pdb:4M76|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5FO7|rcsb pdb:5FO8|rcsb pdb:5FO9|rcsb pdb:5FOA|rcsb pdb:5FOB|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:6EHG|rcsb pdb:6RMT|rcsb pdb:6RMU|rcsb pdb:6RUR|rcsb pdb:6RUV|rcsb pdb:6S0B|rcsb pdb:6YO6|reactome:R-HSA-173736|reactome:R-HSA-174577|reactome:R-HSA-198933|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-418594|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9660826|reactome:R-HSA-977606|uniprotkb:P01024(identity)|refseq:NM_000064(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045601(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1716|chain-seq-end:1976	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 439 nucleotides long and that maps to nucleotides 1889 to 2328 of the RefSeq entry NM_000064.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:6Axa89cCPpUXFsLnd7sCurZzLYI9606	rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411	intact-crc:217E32B93DFA0076|rigid:t76+CXkABgTjqAt1Tbr4MxNZpU8	false	sufficient binding region:?-?	sufficient binding region:198-261	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y5W7	uniprotkb:Q99IB8-PRO_0000045601	intact:EBI-4401489|uniprotkb:Q6PI37|uniprotkb:Q9BSD1|uniprotkb:B4DI55|uniprotkb:Q4VBR3|uniprotkb:Q5TCF9|uniprotkb:Q5TCG0|uniprotkb:Q6NUI7|ensembl:ENSP00000313121	intact:EBI-6928570|intact:EBI-8786387	psi-mi:snx14_human(display_long)|uniprotkb:SNX14(gene name)|psi-mi:SNX14(display_short)	psi-mi:q99ib8-pro_0000045601(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928602|imex:IM-21137-48	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065201.1|refseq:NP_722523.1|refseq:NP_001291408.1|refseq:NP_001284543.1|ensembl:ENSG00000135317(gene)|ensembl:ENST00000314673(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR001683(Phox-like)|interpro:IPR003114(PX-associated)|interpro:IPR013937(Sorting nexin, C-terminal)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR036305|interpro:IPR036871|interpro:IPR037436|interpro:IPR037892|rcsb pdb:4BGJ|rcsb pdb:4PQO|rcsb pdb:4PQP|uniprotkb:Q9Y5W7(identity)|refseq:NM_020468(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045601(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1716|chain-seq-end:1976	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 419 nucleotides long and that maps to nucleotides 1093 to 1512 of the RefSeq entry NM_020468.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:a+twl6lGEpR7hRX/P6mYruxJPEw9606	rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411	intact-crc:F5DFB93B2836618D|rigid:v7E7QbTs+oO9Ke9b1fNPFByeBGg	false	sufficient binding region:?-?	sufficient binding region:198-261	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q13464	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-876651|uniprotkb:B0YJ91|uniprotkb:Q2KHM4|uniprotkb:Q59GZ4|ensembl:ENSP00000382697	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:rock1_human(display_long)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase 1(gene name synonym)|uniprotkb:p160 ROCK-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-35(gene name synonym)|uniprotkb:ROCK1(gene name)|psi-mi:ROCK1(display_short)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase I(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928617|imex:IM-21137-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	refseq:NP_005397.1|dip:DIP-35645N|ensembl:ENSG00000067900(gene)|ensembl:ENST00000399799(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032059"(bleb)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051045"(negative regulation of membrane protein ectodomain proteolysis)|go:"GO:0051451"(myoblast migration)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0072518"(Rho-dependent protein serine/threonine kinase activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110061"(regulation of angiotensin-activated signaling pathway)|go:"GO:0140058"(neuron projection arborization)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1905205"(positive regulation of connective tissue replacement)|go:"GO:1990776"(response to angiotensin)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015008(Rho Binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684|interpro:IPR037310|mint:Q13464|rcsb pdb:1S1C|rcsb pdb:2ESM|rcsb pdb:2ETK|rcsb pdb:2ETR|rcsb pdb:2V55|rcsb pdb:3D9V|rcsb pdb:3NCZ|rcsb pdb:3NDM|rcsb pdb:3O0Z|rcsb pdb:3TV7|rcsb pdb:3TWJ|rcsb pdb:3V8S|rcsb pdb:4L2W|rcsb pdb:4W7P|rcsb pdb:4YVC|rcsb pdb:4YVE|rcsb pdb:5BML|rcsb pdb:5F5P|rcsb pdb:5HVU|rcsb pdb:5KKS|rcsb pdb:5KKT|rcsb pdb:5UZJ|rcsb pdb:5WNE|rcsb pdb:5WNF|rcsb pdb:5WNG|rcsb pdb:5WNH|rcsb pdb:6E9W|rcsb pdb:7JOU|reactome:R-HSA-111465|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5627117|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013407|reactome:R-HSA-9013422|reactome:R-HSA-9679191|reactome:R-HSA-9696264|uniprotkb:Q13464(identity)|refseq:NM_005406(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 252 nucleotides long and that maps to nucleotides 3552 to 3804 of the RefSeq entry NM_005406.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:1YIjRC+RHWK9pmiq8kSBFiZcll49606	intact-crc:2DB4186F6DD26AD0|rigid:enQLxn/6qCZ7FsTDGxV+LZVj/g8	false	sufficient binding region:1-570	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:P02649	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-1222467|uniprotkb:C0JYY5|uniprotkb:Q9P2S4|uniprotkb:B2RC15|ensembl:ENSP00000252486	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:apoe_human(display_long)|uniprotkb:APOE(gene name)|psi-mi:APOE(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928632|imex:IM-21137-50	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	refseq:NP_000032.1|refseq:NP_001289617.1|refseq:NP_001289618.1|refseq:NP_001289619.1|refseq:NP_001289620.1|dip:DIP-1120N|ensembl:ENSG00000130203(gene)|ensembl:ENST00000252486(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010467"(gene expression)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010877"(lipid transport involved in lipid storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016209"(antioxidant activity)|go:"GO:0017038"(protein import)|go:"GO:0019068"(virion assembly)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030425"(dendrite)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032805"(positive regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034447"(very-low-density lipoprotein particle clearance)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0046907"(intracellular transport)|go:"GO:0046911"(metal chelating activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0051651"(maintenance of location in cell)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061771"(response to caloric restriction)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0071830"(triglyceride-rich lipoprotein particle clearance)|go:"GO:0071831"(intermediate-density lipoprotein particle clearance)|go:"GO:0072562"(blood microparticle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0090209"(negative regulation of triglyceride metabolic process)|go:"GO:0090370"(negative regulation of cholesterol efflux)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901627"(negative regulation of postsynaptic membrane organization)|go:"GO:1901631"(positive regulation of presynaptic membrane organization)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1902999"(negative regulation of phospholipid efflux)|go:"GO:1903001"(negative regulation of lipid transport across blood-brain barrier)|go:"GO:1903002"(positive regulation of lipid transport across blood-brain barrier)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1905855"(positive regulation of heparan sulfate binding)|go:"GO:1905860"(positive regulation of heparan sulfate proteoglycan binding)|go:"GO:1905890"(regulation of cellular response to very-low-density lipoprotein particle stimulus)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:1990777"(lipoprotein particle)|go:"GO:2000822"(regulation of behavioral fear response)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:P02649|rcsb pdb:1B68|rcsb pdb:1BZ4|rcsb pdb:1EA8|rcsb pdb:1GS9|rcsb pdb:1H7I|rcsb pdb:1LE2|rcsb pdb:1LE4|rcsb pdb:1LPE|rcsb pdb:1NFN|rcsb pdb:1NFO|rcsb pdb:1OEF|rcsb pdb:1OEG|rcsb pdb:1OR2|rcsb pdb:1OR3|rcsb pdb:2KC3|rcsb pdb:2KNY|rcsb pdb:2L7B|rcsb pdb:6IWB|rcsb pdb:6NCN|rcsb pdb:6NCO|reactome:R-HSA-1251985|reactome:R-HSA-3000480|reactome:R-HSA-381426|reactome:R-HSA-8864260|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964058|reactome:R-HSA-9029569|reactome:R-HSA-975634|reactome:R-HSA-977225|uniprotkb:P02649(identity)|refseq:NM_000041(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 463 nucleotides long and that maps to nucleotides 49 to 512 of the RefSeq entry NM_000041.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:vnCU03+HdGblqtALKeOTZRx5/3E9606	intact-crc:9C43884148C5CA16|rigid:Ih3tQWUyiWBd7DljIH38zdICI1c	false	sufficient binding region:356-466	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P45973	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928647|imex:IM-21137-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N|uniprotkb:P45973(identity)|refseq:NM_012117(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 358 nucleotides long and that maps to nucleotides 1 to 359 of the RefSeq entry NM_012117.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:9C642FF2689089A8|rigid:opK2+qEsHc+A2TuTahM0rHUwdjo	false	sufficient binding region:?-?	sufficient binding region:209-342	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:Q9UNS2	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-350590|uniprotkb:O43191|uniprotkb:Q7LDR6|uniprotkb:B2R683|ensembl:ENSP00000268717|uniprotkb:B4DY81	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:csn3_human(display_long)|uniprotkb:COPS3(gene name)|psi-mi:COPS3(display_short)|uniprotkb:CSN3(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928677|imex:IM-21137-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	refseq:NP_001186054.1|refseq:NP_003644.2|ensembl:ENSG00000141030(gene)|ensembl:ENST00000268717(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009416"(response to light stimulus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR037753|mint:Q9UNS2|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|rcsb pdb:6R6H|refseq:NP_001303283.1|refseq:NP_001303284.1|refseq:NP_001303285.1|refseq:NP_001303286.1|refseq:NP_001303287.1|refseq:XP_005256894.1|dip:DIP-32478N|uniprotkb:Q9UNS2(identity)|refseq:NM_003653(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 531 nucleotides long and that maps to nucleotides 94 to 625 of the RefSeq entry NM_003653.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:z6E/tPEo/ksVxD5Yyfo89t+ww989606	intact-crc:16DE8C016D036080|rigid:PXHkB9oaT3YsgNVOieNsEcJXW28	false	sufficient binding region:36-213	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:Q96MT8	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928662|imex:IM-21137-52	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N|uniprotkb:Q96MT8(identity)|refseq:NM_001042384(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 361 nucleotides long and that maps to nucleotides 389 to 750 of the RefSeq entry NM_001042384.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606	intact-crc:7847E2640DC7B5A8|rigid:tlZUiWqTz9iM+EMgXriBCvD4pOs	false	sufficient binding region:36-213	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:Q15717	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928707|imex:IM-21137-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N|uniprotkb:Q15717(identity)|refseq:NM_001419(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 438 nucleotides long and that maps to nucleotides 683 to 1121 of the RefSeq entry NM_001419.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606	intact-crc:7AE21CAE6C85A890|rigid:k+WlCqKa+OAPYL4vrTViJ3I4MrM	false	sufficient binding region:209-342	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96KQ7	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928692|imex:IM-21137-54	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|refseq:NM_025256(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 629 nucleotides long and that maps to nucleotides 1920 to 2549 of the RefSeq entry NM_025256.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:56B58C9DC9866346|rigid:oJ9egF+VkoP3DFfNDRrvWZsHWHs	false	sufficient binding region:?-?	sufficient binding region:36-213	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:Q5JTC6	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-6169747|uniprotkb:A2IB86|uniprotkb:Q8N885|ensembl:ENSP00000364003	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:amer1_human(display_long)|uniprotkb:AMER1(gene name)|psi-mi:AMER1(display_short)|uniprotkb:FAM123B(gene name synonym)|uniprotkb:Protein FAM123B(gene name synonym)|uniprotkb:WTX(gene name synonym)|uniprotkb:Wilms tumor gene on the X chromosome protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928722|imex:IM-21137-56	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	refseq:NP_689637.3|reactome:R-HSA-5467348|ensembl:ENSG00000184675(gene)|ensembl:ENST00000374869(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060348"(bone development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0072161"(mesenchymal cell differentiation involved in kidney development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904713"(beta-catenin destruction complex binding)|interpro:IPR019003|mint:Q5JTC6|rcsb pdb:4YJE|rcsb pdb:4YJL|rcsb pdb:4YK6|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|uniprotkb:Q5JTC6(identity)|refseq:NM_152424(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 634 nucleotides long and that maps to nucleotides 776 to 1410 of the RefSeq entry NM_152424.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:sRFifjRWQ45q8lSqsBPcCpYxM0Y9606	intact-crc:8517446E803D4580|rigid:E853D5TiGx3TpQD1haOALyNFA5s	false	sufficient binding region:209-342	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02675	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-1034445|uniprotkb:A0JLR9|uniprotkb:Q32Q65|uniprotkb:Q3KPF2|uniprotkb:B2R7G3|ensembl:ENSP00000306099	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:fibb_human(display_long)|uniprotkb:FGB(gene name)|psi-mi:FGB(display_short)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928737|imex:IM-21137-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171670.1|refseq:NP_005132.2|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:P02675|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|ensembl:ENSG00000171564(gene)|ensembl:ENST00000302068(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|reactome:R-HSA-6802948|dip:DIP-385N|uniprotkb:P02675(identity)|refseq:NM_005141(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 610 nucleotides long and that maps to nucleotides 466 to 1076 of the RefSeq entry NM_005141.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:cbcOBnZB/W/Y7eE/IxM2HfZHpK49606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:3105DD12DCD14A63|rigid:7do70BmpChzwyFeqsmLjXG/eP/s	false	sufficient binding region:?-?	sufficient binding region:209-342	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02751	uniprotkb:Q99IB8-PRO_0000045602	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928767|imex:IM-21137-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|uniprotkb:P02751(identity)|refseq:NM_212475(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1977|chain-seq-end:2442	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 266 nucleotides long and that maps to nucleotides 4062 to 4328 of the RefSeq entry NM_212475.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2019/10/18	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	intact-crc:47B07102A350BB3C|rigid:49EmdIWW+bya2dqOlvBgLJFYi78	false	sufficient binding region:?-?	sufficient binding region:209-342	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045602	uniprotkb:P02675	intact:EBI-6927873|intact:EBI-9232975|intact:EBI-6931023	intact:EBI-1034445|uniprotkb:A0JLR9|uniprotkb:Q32Q65|uniprotkb:Q3KPF2|uniprotkb:B2R7G3|ensembl:ENSP00000306099	psi-mi:q99ib8-pro_0000045602(display_long)	psi-mi:fibb_human(display_long)|uniprotkb:FGB(gene name)|psi-mi:FGB(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928752|imex:IM-21137-58	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045602(identity)	refseq:NP_001171670.1|refseq:NP_005132.2|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:P02675|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|ensembl:ENSG00000171564(gene)|ensembl:ENST00000302068(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|reactome:R-HSA-6802948|dip:DIP-385N|uniprotkb:P02675(identity)|refseq:NM_005141(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1977|chain-seq-end:2442	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 843 nucleotides long and that maps to nucleotides 106 to 949 of the RefSeq entry NM_005141.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:qAEcnahT9EPJdIQhjuLxeAPuJ+M356411	rogid:cbcOBnZB/W/Y7eE/IxM2HfZHpK49606	intact-crc:A00F1B99EDD87F19|rigid:7do70BmpChzwyFeqsmLjXG/eP/s	false	sufficient binding region:36-213	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045601	uniprotkb:Q9GZR7	intact:EBI-6928570|intact:EBI-8786387	intact:EBI-713081|ensembl:ENSP00000481495|ensembl:ENSP00000482106|uniprotkb:E7EMJ4|uniprotkb:Q4V9L5	psi-mi:q99ib8-pro_0000045601(display_long)	psi-mi:ddx24_human(display_long)|uniprotkb:DEAD box protein 24(gene name synonym)|uniprotkb:DDX24(gene name)|psi-mi:DDX24(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928782|imex:IM-21137-60	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045601(identity)	ensembl:ENSG00000089737(gene)|ensembl:ENSG00000273761(gene)|ensembl:ENST00000613280(transcript)|ensembl:ENST00000621632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR027417|mint:Q9GZR7|refseq:NP_065147.1|dip:DIP-47301N|uniprotkb:Q9GZR7(identity)|refseq:NM_020414(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1716|chain-seq-end:1976	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 546 nucleotides long and that maps to nucleotides 200 to 746 of the RefSeq entry NM_020414.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:9V9Qr4j9EH+1xmq3GXm39eFxJYU356411	rogid:n9gQabTC50Y/LtGMAMFNVgj12as9606	intact-crc:18A84B56F213C016|rigid:nmi4AqNneslJazQMCXk+j4n63dg	false	sufficient binding region:198-261	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96KQ7	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957	intact:EBI-6858501|intact:EBI-6927943	psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928797|imex:IM-21137-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N|uniprotkb:Q96KQ7(identity)|refseq:NM_025256(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 646 nucleotides long and that maps to nucleotides 1920 to 2566 of the RefSeq entry NM_025256.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:26973619C3FFC84C|rigid:AIkh03S1tzDoUt81NuRtWCHVPfk	false	sufficient binding region:?-?	sufficient binding region:1-200	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02818	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-2622179|uniprotkb:Q7Z4J7|uniprotkb:B2RD64|uniprotkb:Q9BUR1|uniprotkb:Q15838|intact:EBI-28978015|ensembl:ENSP00000385211|ensembl:ENSP00000385923	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:nucb1_human(display_long)|uniprotkb:NUC(gene name synonym)|uniprotkb:CALNUC(gene name synonym)|uniprotkb:NUCB1(gene name)|psi-mi:NUCB1(display_short)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928812|imex:IM-21137-62	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000385923|ensembl:ENSP00000385211|refseq:NP_006175.2|refseq:XP_016882334.1|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0098547"(lumenal side of Golgi membrane)|go:"GO:1903533"(regulation of protein targeting)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040250|interpro:IPR040253|mint:Q02818|rcsb pdb:1SNL|reactome:R-HSA-381426|reactome:R-HSA-8957275|ensembl:ENSG00000104805(gene)|ensembl:ENST00000405315(transcript)|ensembl:ENST00000407032(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|uniprotkb:Q02818(identity)|refseq:NM_006184(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 534 nucleotides long and that maps to nucleotides 764 to 1298 of the RefSeq entry NM_006184.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:exoVYPq5+NxEpgkm/gAQay/Uwuk9606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:8F0712708412A6B1|rigid:YSaKPvIbPqWO0JTcS5mS4ju7Ako	false	sufficient binding region:?-?	sufficient binding region:367-531	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045598	uniprotkb:P50440	intact:EBI-6901421|intact:EBI-6928831	intact:EBI-2552594|uniprotkb:Q53EQ4|uniprotkb:B4DH99|uniprotkb:B4DPI3|ensembl:ENSP00000379895	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:gatm_human(display_long)|uniprotkb:AGAT(gene name synonym)|uniprotkb:"L-arginine:glycine amidinotransferase"(gene name synonym)|uniprotkb:Transamidinase(gene name synonym)|uniprotkb:GATM(gene name)|psi-mi:GATM(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928827|imex:IM-21137-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	refseq:NP_001473.1|ensembl:ENSG00000171766(gene)|ensembl:ENST00000396659(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006600"(creatine metabolic process)|go:"GO:0006601"(creatine biosynthetic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007611"(learning or memory)|go:"GO:0014889"(muscle atrophy)|go:"GO:0015067"(amidinotransferase activity)|go:"GO:0015068"(glycine amidinotransferase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR033195|rcsb pdb:1JDW|rcsb pdb:1JDX|rcsb pdb:2JDW|rcsb pdb:2JDX|rcsb pdb:3JDW|rcsb pdb:4JDW|rcsb pdb:5JDW|rcsb pdb:6JDW|rcsb pdb:7JDW|rcsb pdb:8JDW|rcsb pdb:9JDW|reactome:R-HSA-71288|uniprotkb:P50440(identity)|refseq:NM_001482(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:814|chain-seq-end:1030	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 390 nucleotides long and that maps to nucleotides 275 to 665 of the RefSeq entry NM_001482.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	rogid:FYkmOSpHilJ5gCuPd5PQ3dIQiy89606	intact-crc:7C3FF84630513B62|rigid:ZcRlw9ew4giktvj6swC5eFmW6Os	false	sufficient binding region:100-217	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045598	uniprotkb:Q13576	intact:EBI-6901421|intact:EBI-6928831	intact:EBI-357571|uniprotkb:J3KR91|uniprotkb:A8K4V1|uniprotkb:B7Z8A4|ensembl:ENSP00000274364	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:iqga2_human(display_long)|uniprotkb:IQGAP2(gene name)|psi-mi:IQGAP2(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928844|imex:IM-21137-64	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	refseq:NP_001272389.1|refseq:NP_001272390.1|refseq:NP_001272391.1|refseq:NP_006624.2|ensembl:ENSG00000145703(gene)|ensembl:ENST00000274364(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070493"(thrombin-activated receptor signaling pathway)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036872|mint:Q13576|rcsb pdb:3IEZ|rcsb pdb:4EZA|rcsb pdb:5CJP|reactome:R-HSA-5626467|reactome:R-HSA-6798695|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|dip:DIP-27542N|uniprotkb:Q13576(identity)|refseq:NM_006633(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:814|chain-seq-end:1030	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 403 nucleotides long and that maps to nucleotides 1040 to 1443 of the RefSeq entry NM_006633.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	rogid:gmxbOFcisiWIsQrHFQCoI5y49T09606	intact-crc:3028F81EE25C7035|rigid:siAGaYvB7hn7V+KA3KU0d5q0YF8	false	sufficient binding region:100-217	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045598	uniprotkb:P01024	intact:EBI-6901421|intact:EBI-6928831	intact:EBI-905851|uniprotkb:A7E236|ensembl:ENSP00000245907	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:co3_human(display_long)|uniprotkb:C3(gene name)|psi-mi:C3(display_short)|uniprotkb:CPAMD1(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928859|imex:IM-21137-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	refseq:NP_000055.2|dip:DIP-35180N|ensembl:ENSG00000125730(gene)|ensembl:ENST00000245907(transcript)|go:"GO:0001798"(positive regulation of type IIa hypersensitivity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001970"(positive regulation of activation of membrane attack complex)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006956"(complement activation)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0016322"(neuron remodeling)|go:"GO:0031715"(C5L2 anaphylatoxin chemotactic receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035846"(oviduct epithelium development)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1905114"(cell surface receptor signaling pathway involved in cell-cell signaling)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR035711|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|mint:P01024|rcsb pdb:1C3D|rcsb pdb:1GHQ|rcsb pdb:1W2S|rcsb pdb:2A73|rcsb pdb:2A74|rcsb pdb:2GOX|rcsb pdb:2I07|rcsb pdb:2ICE|rcsb pdb:2ICF|rcsb pdb:2NOJ|rcsb pdb:2QKI|rcsb pdb:2WII|rcsb pdb:2WIN|rcsb pdb:2WY7|rcsb pdb:2WY8|rcsb pdb:2XQW|rcsb pdb:2XWB|rcsb pdb:2XWJ|rcsb pdb:3D5R|rcsb pdb:3D5S|rcsb pdb:3G6J|rcsb pdb:3L3O|rcsb pdb:3L5N|rcsb pdb:3NMS|rcsb pdb:3OED|rcsb pdb:3OHX|rcsb pdb:3OXU|rcsb pdb:3RJ3|rcsb pdb:3T4A|rcsb pdb:4HW5|rcsb pdb:4HWJ|rcsb pdb:4I6O|rcsb pdb:4M76|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5FO7|rcsb pdb:5FO8|rcsb pdb:5FO9|rcsb pdb:5FOA|rcsb pdb:5FOB|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:6EHG|rcsb pdb:6RMT|rcsb pdb:6RMU|rcsb pdb:6RUR|rcsb pdb:6RUV|rcsb pdb:6S0B|rcsb pdb:6YO6|reactome:R-HSA-173736|reactome:R-HSA-174577|reactome:R-HSA-198933|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-418594|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9660826|reactome:R-HSA-977606|uniprotkb:P01024(identity)|refseq:XM_001719463(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:814|chain-seq-end:1030	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 429 nucleotides long and that maps to nucleotides 1920 to 2349 of the RefSeq entry XM_001719463.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	rogid:6Axa89cCPpUXFsLnd7sCurZzLYI9606	intact-crc:5F71CEC1C4CF199E|rigid:WQXjFvmXcE8btkryBIHt+ksABGE	false	sufficient binding region:100-217	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045598	uniprotkb:Q9H074	intact:EBI-6901421|intact:EBI-6928831	intact:EBI-81519|uniprotkb:O60455|uniprotkb:Q96B61|uniprotkb:Q9BS63|intact:EBI-28983264|ensembl:ENSP00000302768|intact:EBI-11149865|uniprotkb:A6NKV8	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:paip1_human(display_long)|uniprotkb:PAIP1(gene name)|psi-mi:PAIP1(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928874|imex:IM-21137-66	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	refseq:NP_006442.2|refseq:NP_877590.1|refseq:NP_899152.1|rcsb pdb:1JH4|rcsb pdb:3NTW|rcsb pdb:3RK6|rcsb pdb:6YXJ|reactome:R-HSA-429947|mint:Q9H074|ensembl:ENSG00000172239(gene)|ensembl:ENST00000306846(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0048255"(mRNA stabilization)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|refseq:XP_016864445.1|ensembl:ENSP00000339622|ensembl:ENST00000436644|ensembl:ENSP00000387729|ensembl:ENST00000338972|ensembl:ENSP00000302768|refseq:XP_005248287.1|uniprotkb:Q9H074(identity)|refseq:NM_006451(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:814|chain-seq-end:1030	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 513 nucleotides long and that maps to nucleotides 1052 to 1565 of the RefSeq entry NM_006451.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	rogid:KPInpN26l8XAnUKFawoVUhwKM9w9606	intact-crc:B7441A337356657E|rigid:Ubsix8BmdyeIWilQBYkLDAeLhIk	false	sufficient binding region:100-217	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UQ90	uniprotkb:Q99IB8-PRO_0000045598	intact:EBI-717201|uniprotkb:Q58F00|uniprotkb:O75756|uniprotkb:Q2TB70|uniprotkb:Q96IB0|ensembl:ENSP00000495795	intact:EBI-6901421|intact:EBI-6928831	psi-mi:spg7_human(display_long)|uniprotkb:Spastic paraplegia 7 protein(gene name synonym)|uniprotkb:SPG7(gene name)|psi-mi:SPG7(display_short)|uniprotkb:CAR(gene name synonym)|uniprotkb:PGN(gene name synonym)|uniprotkb:CMAR(gene name synonym)|uniprotkb:Cell matrix adhesion regulator(gene name synonym)	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928908|imex:IM-21137-68	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003110.1|refseq:NP_955399.1|refseq:XP_016879088.1|ensembl:ENSG00000197912(gene)|ensembl:ENST00000645818(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005745"(m-AAA complex)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007399"(nervous system development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008233"(peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0042407"(cristae formation)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1902686"(mitochondrial outer membrane permeabilization involved in programmed cell death)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9UQ90|rcsb pdb:2QZ4|reactome:R-HSA-8949664|go:"GO:0005743"(mitochondrial inner membrane)|uniprotkb:Q9UQ90(identity)|refseq:NM_003119(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:814|chain-seq-end:1030	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 377 nucleotides long and that maps to nucleotides 479 to 856 of the RefSeq entry NM_003119.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:mZ5/BJQnv0IF5nCFM17RzeklKDo9606	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	intact-crc:17EA0A2D7786729A|rigid:KWvBcqMhY0lu7n/SOgf5fnVoM/k	false	sufficient binding region:?-?	sufficient binding region:100-217	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045598	uniprotkb:Q13670	intact:EBI-6901421|intact:EBI-6928831	intact:EBI-6928893	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:pm2pb_human(display_long)|uniprotkb:PMS2-related protein 6(gene name synonym)|uniprotkb:PMS2L11(gene name synonym)|uniprotkb:PMSR6(gene name synonym)|uniprotkb:Putative postmeiotic segregation increased 2 pseudogene 11(gene name synonym)|uniprotkb:PMS2P11(gene name)|psi-mi:PMS2P11(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928889|imex:IM-21137-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	go:"GO:0006298"(mismatch repair)|go:"GO:0016301"(kinase activity)|go:"GO:0032300"(mismatch repair complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036890|interpro:IPR024828|interpro:IPR024831|uniprotkb:Q13670(identity)|refseq:NR_023383(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:814|chain-seq-end:1030	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 237 nucleotides long and that maps to nucleotides 717 to 954 of the RefSeq entry NR_023383.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	rogid:Xr1FnxxI5gmj2X/Dq9I5F8far7c9606	intact-crc:537C8AD967D7EBAA|rigid:qelowZNwZAiQVBDd2icgokXzPRI	false	sufficient binding region:100-217	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045598	uniprotkb:O14763	intact:EBI-6901421|intact:EBI-6928831	intact:EBI-518882|uniprotkb:Q6UXM8|uniprotkb:Q7Z360|uniprotkb:O14720|uniprotkb:O15508|uniprotkb:O15517|uniprotkb:O15531|uniprotkb:Q9BVE0|ensembl:ENSP00000276431	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:tr10b_human(display_long)|uniprotkb:Death receptor 5(gene name synonym)|uniprotkb:TNF-related apoptosis-inducing ligand receptor 2(gene name synonym)|uniprotkb:UNQ160/PRO186(orf name)|uniprotkb:TNFRSF10B(gene name)|psi-mi:TNFRSF10B(display_short)|uniprotkb:DR5(gene name synonym)|uniprotkb:KILLER(gene name synonym)|uniprotkb:TRAILR2(gene name synonym)|uniprotkb:TRICK2(gene name synonym)|uniprotkb:ZTNFR9(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928938|imex:IM-21137-70	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	refseq:NP_003833.4|refseq:NP_671716.2|dip:DIP-33566N|ensembl:ENSG00000120889(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0036463"(TRAIL receptor activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045569"(TRAIL binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071260"(cellular response to mechanical stimulus)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR020465|interpro:IPR034024|interpro:IPR034029|rcsb pdb:1D0G|rcsb pdb:1D4V|rcsb pdb:1DU3|rcsb pdb:1ZA3|rcsb pdb:2H9G|rcsb pdb:3X3F|rcsb pdb:4I9X|rcsb pdb:4N90|rcsb pdb:4OD2|rcsb pdb:6NHW|rcsb pdb:6NHY|rcsb pdb:6T3J|reactome:R-HSA-140534|reactome:R-HSA-202733|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75158|ensembl:ENST00000276431(transcript)|uniprotkb:O14763(identity)|refseq:NM_003842(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:814|chain-seq-end:1030	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 460 nucleotides long and that maps to nucleotides 1069 to 1529 of the RefSeq entry NM_003842.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	rogid:V021Tohje+gkHyYH6iOOnN/IBJ49606	intact-crc:346942219F07D7E7|rigid:uI7Fe3wgJnhzgd7C5JPULetqhiY	false	sufficient binding region:100-217	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UNK0	uniprotkb:Q99IB8-PRO_0000045598	intact:EBI-727240|uniprotkb:O60712|uniprotkb:Q53XT8|ensembl:ENSP00000305255	intact:EBI-6901421|intact:EBI-6928831	psi-mi:stx8_human(display_long)|uniprotkb:STX8(gene name)|psi-mi:STX8(display_short)	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928923|imex:IM-21137-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004844.1|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR041875|mint:Q9UNK0|ensembl:ENSG00000170310(gene)|ensembl:ENST00000306357(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|dip:DIP-47274N|uniprotkb:Q9UNK0(identity)|refseq:NM_004853(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:814|chain-seq-end:1030	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 396 nucleotides long and that maps to nucleotides 180 to 576 of the RefSeq entry NM_004853.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:jdsUOdy99aWRb94ndPtawff7z/o9606	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	intact-crc:4FA084D9B8FCB210|rigid:rC3GBjNdVY9xfHiOVakqKhXBvfs	false	sufficient binding region:?-?	sufficient binding region:100-217	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:P55265	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-2462104|uniprotkb:B1AQR0|uniprotkb:O15223|uniprotkb:O43859|uniprotkb:O43860|uniprotkb:Q9BYM3|uniprotkb:Q9BYM4|uniprotkb:B1AQQ9|uniprotkb:D3DV76|ensembl:ENSP00000357459	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:dsrad_human(display_long)|uniprotkb:ADAR(gene name)|psi-mi:ADAR(display_short)|uniprotkb:ADAR1(gene name synonym)|uniprotkb:DSRAD(gene name synonym)|uniprotkb:G1P1(gene name synonym)|uniprotkb:IFI4(gene name synonym)|uniprotkb:136 kDa double-stranded RNA-binding protein(gene name synonym)|uniprotkb:K88DSRBP(gene name synonym)|uniprotkb:Interferon-inducible protein 4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928953|imex:IM-21137-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	refseq:NP_001020278.1|refseq:NP_001102.2|refseq:NP_001180424.1|refseq:NP_056655.2|refseq:NP_056656.2|refseq:XP_006711174.1|refseq:XP_006711175.1|refseq:XP_006711176.1|dip:DIP-29310N|ensembl:ENSG00000160710(gene)|ensembl:ENST00000368474(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002566"(somatic diversification of immune receptors via somatic mutation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008251"(tRNA-specific adenosine deaminase activity)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900369"(negative regulation of RNA interference)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371|interpro:IPR044456|interpro:IPR044457|mint:P55265|rcsb pdb:1QBJ|rcsb pdb:1QGP|rcsb pdb:1XMK|rcsb pdb:2ACJ|rcsb pdb:2GXB|rcsb pdb:2L54|rcsb pdb:2MDR|rcsb pdb:3F21|rcsb pdb:3F22|rcsb pdb:3F23|rcsb pdb:3IRQ|rcsb pdb:3IRR|rcsb pdb:5ZU1|rcsb pdb:5ZUO|rcsb pdb:5ZUP|rcsb pdb:7C0I|reactome:R-HSA-75102|reactome:R-HSA-77042|reactome:R-HSA-909733|go:"GO:0051607"(defense response to virus)|uniprotkb:P55265(identity)|refseq:NM_001025107(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 751 nucleotides long and that maps to nucleotides 1250 to 2001 of the RefSeq entry NM_001025107.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:rP/Yr/h8WLSFNdIuqWnYtZjZ9qI9606	intact-crc:23D91465FFEE7FB4|rigid:ky4nPTe9aCnVWMOWE4cGOpUIPfg	false	sufficient binding region:135-631	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55265	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-2462104|uniprotkb:B1AQR0|uniprotkb:O15223|uniprotkb:O43859|uniprotkb:O43860|uniprotkb:Q9BYM3|uniprotkb:Q9BYM4|uniprotkb:B1AQQ9|uniprotkb:D3DV76|ensembl:ENSP00000357459	intact:EBI-6858501|intact:EBI-6927943	psi-mi:dsrad_human(display_long)|uniprotkb:ADAR(gene name)|psi-mi:ADAR(display_short)|uniprotkb:ADAR1(gene name synonym)|uniprotkb:DSRAD(gene name synonym)|uniprotkb:G1P1(gene name synonym)|uniprotkb:IFI4(gene name synonym)|uniprotkb:136 kDa double-stranded RNA-binding protein(gene name synonym)|uniprotkb:K88DSRBP(gene name synonym)|uniprotkb:Interferon-inducible protein 4(gene name synonym)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928968|imex:IM-21137-72	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020278.1|refseq:NP_001102.2|refseq:NP_001180424.1|refseq:NP_056655.2|refseq:NP_056656.2|refseq:XP_006711174.1|refseq:XP_006711175.1|refseq:XP_006711176.1|dip:DIP-29310N|ensembl:ENSG00000160710(gene)|ensembl:ENST00000368474(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002566"(somatic diversification of immune receptors via somatic mutation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008251"(tRNA-specific adenosine deaminase activity)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900369"(negative regulation of RNA interference)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371|interpro:IPR044456|interpro:IPR044457|mint:P55265|rcsb pdb:1QBJ|rcsb pdb:1QGP|rcsb pdb:1XMK|rcsb pdb:2ACJ|rcsb pdb:2GXB|rcsb pdb:2L54|rcsb pdb:2MDR|rcsb pdb:3F21|rcsb pdb:3F22|rcsb pdb:3F23|rcsb pdb:3IRQ|rcsb pdb:3IRR|rcsb pdb:5ZU1|rcsb pdb:5ZUO|rcsb pdb:5ZUP|rcsb pdb:7C0I|reactome:R-HSA-75102|reactome:R-HSA-77042|reactome:R-HSA-909733|go:"GO:0051607"(defense response to virus)|uniprotkb:P55265(identity)|refseq:NM_001111(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 446 nucleotides long and that maps to nucleotides 1332 to 1778 of the RefSeq entry NM_001111.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:rP/Yr/h8WLSFNdIuqWnYtZjZ9qI9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:15DC75D06B7C7E48|rigid:ky4nPTe9aCnVWMOWE4cGOpUIPfg	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:Q8N302	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-747899|ensembl:ENSP00000316109|uniprotkb:O00581|uniprotkb:Q53YS3|uniprotkb:Q9BU84|uniprotkb:Q9NW66|intact:EBI-28984369	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:aggf1_human(display_long)|uniprotkb:Angiogenic factor VG5Q(gene name synonym)|uniprotkb:Vasculogenesis gene on 5q protein(gene name synonym)|uniprotkb:G patch domain-containing protein 7(gene name synonym)|uniprotkb:AGGF1(gene name)|psi-mi:AGGF1(display_short)|uniprotkb:VG5Q(gene name synonym)|uniprotkb:GPATC7(gene name synonym)|uniprotkb:GPATCH7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928981|imex:IM-21137-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	ensembl:ENSG00000164252(gene)|ensembl:ENST00000312916(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007155"(cell adhesion)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000467(D111/G-patch)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR035624|interpro:IPR041591|refseq:NP_060516.2|mint:Q8N302|reactome:R-HSA-6802952|ensembl:ENST00000506806|ensembl:ENSP00000424733|ensembl:ENSP00000316109|uniprotkb:Q8N302(identity)|refseq:NM_018046(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 789 nucleotides long and that maps to nucleotides 819 to 1608 of the RefSeq entry NM_018046.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:5FA3UwL9w6K00rccLnd3fwIs8oo9606	intact-crc:98DA4227A7CBF9B7|rigid:BMtdOF8UVH7Do7UFtxZ3u4lHvLk	false	sufficient binding region:135-631	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045598	uniprotkb:P61201	intact:EBI-6901421|intact:EBI-6928831	intact:EBI-1050386|uniprotkb:O88950|uniprotkb:Q15647|uniprotkb:Q6FGP4|uniprotkb:Q9BY54|uniprotkb:Q9R249|uniprotkb:Q9UNI2|uniprotkb:Q9UNQ5|ensembl:ENSP00000373553	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:csn2_human(display_long)|uniprotkb:JAB1-containing signalosome subunit 2(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 15(gene name synonym)|uniprotkb:Alien homolog(gene name synonym)|uniprotkb:COPS2(gene name)|psi-mi:COPS2(display_short)|uniprotkb:CSN2(gene name synonym)|uniprotkb:TRIP15(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6928996|imex:IM-21137-74	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	refseq:NP_001137359.1|refseq:NP_004227.1|ensembl:ENSG00000166200(gene)|ensembl:ENST00000388901(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR037750|mint:P61201|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6A73|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|dip:DIP-42076N|uniprotkb:P61201(identity)|refseq:NM_004236(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:814|chain-seq-end:1030	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 395 nucleotides long and that maps to nucleotides 29 to 424 of the RefSeq entry NM_004236.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	rogid:MrlEHktIBvvcQux7Z7kqYJYgbbs9606	intact-crc:27D9C82385C23577|rigid:dWQmwN9iyzF7C1/ft1ge+V7wF5U	false	sufficient binding region:100-217	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96MT8	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-741977|uniprotkb:Q96CR0|uniprotkb:Q9H8F5|uniprotkb:Q9H8N0|uniprotkb:D3DND8|uniprotkb:D3DND9|uniprotkb:D3DNE0|ensembl:ENSP00000426129|ensembl:ENSP00000475903|ensembl:ENSP00000502085|ensembl:ENSP00000506896	intact:EBI-6858501|intact:EBI-6927943	psi-mi:cep63_human(display_long)|uniprotkb:CEP63(gene name)|psi-mi:CEP63(display_short)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929011|imex:IM-21137-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000922"(spindle pole)|go:"GO:0005829"(cytosol)|refseq:NP_001035842.1|refseq:NP_001035843.1|refseq:NP_001035859.1|refseq:NP_079456.2|ensembl:ENSG00000182923(gene)|ensembl:ENST00000513612(transcript)|ensembl:ENST00000606977(transcript)|ensembl:ENST00000675561(transcript)|ensembl:ENST00000683596(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005814"(centriole)|go:"GO:0005813"(centrosome)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|interpro:IPR029608|interpro:IPR031470|mint:Q96MT8|rcsb pdb:6CSU|rcsb pdb:6CSV|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0007099"(centriole replication)|refseq:XP_011511496.1|refseq:XP_005247854.1|refseq:XP_006713823.1|refseq:XP_016862743.1|refseq:XP_016862744.1|refseq:XP_016862745.1|refseq:XP_016862751.1|refseq:XP_016862752.1|refseq:XP_016862753.1|refseq:XP_016862755.1|refseq:XP_016862756.1|dip:DIP-36374N|uniprotkb:Q96MT8(identity)|refseq:NM_001042384(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 647 nucleotides long and that maps to nucleotides 351 to 998 of the RefSeq entry NM_001042384.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:/WPfint+sTGNCYCH9XG5rPYSOm09606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:29CA91CA3A8C6DBE|rigid:vKRM5kDNb/rrVztiis/PGm8aVIQ	false	sufficient binding region:?-?	sufficient binding region:135-631	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5JTC6	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-6169747|uniprotkb:A2IB86|uniprotkb:Q8N885|ensembl:ENSP00000364003	intact:EBI-6858501|intact:EBI-6927943	psi-mi:amer1_human(display_long)|uniprotkb:AMER1(gene name)|psi-mi:AMER1(display_short)|uniprotkb:FAM123B(gene name synonym)|uniprotkb:Protein FAM123B(gene name synonym)|uniprotkb:WTX(gene name synonym)|uniprotkb:Wilms tumor gene on the X chromosome protein(gene name synonym)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929041|imex:IM-21137-77	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689637.3|reactome:R-HSA-5467348|ensembl:ENSG00000184675(gene)|ensembl:ENST00000374869(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060348"(bone development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0072161"(mesenchymal cell differentiation involved in kidney development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1904713"(beta-catenin destruction complex binding)|interpro:IPR019003|mint:Q5JTC6|rcsb pdb:4YJE|rcsb pdb:4YJL|rcsb pdb:4YK6|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|uniprotkb:Q5JTC6(identity)|refseq:NM_152424(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 634 nucleotides long and that maps to nucleotides 776 to 1410 of the RefSeq entry NM_152424.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:sRFifjRWQ45q8lSqsBPcCpYxM0Y9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:DCA7569D321E14EF|rigid:Y+EUcJdgln8iZ9LGwLz5FV7+I0c	false	sufficient binding region:?-?	sufficient binding region:135-631	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045598	uniprotkb:Q9P219	intact:EBI-6901421|intact:EBI-6928831	intact:EBI-2807406|uniprotkb:Q86SX7|uniprotkb:Q7L1M2|uniprotkb:Q8IYG8|uniprotkb:Q69YK1|ensembl:ENSP00000374507	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:daple_human(display_long)|uniprotkb:CCDC88C(gene name)|psi-mi:CCDC88C(display_short)|uniprotkb:DAPLE(gene name synonym)|uniprotkb:KIAA1509(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 88C(gene name synonym)|uniprotkb:Dvl-associating protein with a high frequency of leucine residues(gene name synonym)|uniprotkb:Hook-related protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929026|imex:IM-21137-76	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	refseq:NP_001073883.2|ensembl:ENSG00000015133(gene)|ensembl:ENST00000389857(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003383"(apical constriction)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031648"(protein destabilization)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR027719|interpro:IPR036872|interpro:IPR043936|reactome:R-HSA-5368598|uniprotkb:Q9P219(identity)|refseq:NM_001080414(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:814|chain-seq-end:1030	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 532 nucleotides long and that maps to nucleotides 3549 to 4081 of the RefSeq entry NM_001080414.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	rogid:YAtHk2OXKhOgcCerBWS0ObVTLks9606	intact-crc:8DA5387080B71F6B|rigid:/Yvy7eZxTgiCRhmWuXKb/2w0tgw	false	sufficient binding region:100-217	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UK99	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-2509901|uniprotkb:B3KY16|uniprotkb:D3DR05|uniprotkb:Q9H0V2|uniprotkb:Q86X90|uniprotkb:Q9NUX2|ensembl:ENSP00000265651	intact:EBI-6858501|intact:EBI-6927943	psi-mi:fbx3_human(display_long)|uniprotkb:FBXO3(gene name)|psi-mi:FBXO3(display_short)|uniprotkb:FBX3(gene name synonym)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929056|imex:IM-21137-78	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036307.2|refseq:NP_208385.1|dip:DIP-53688N|ensembl:ENSG00000110429(gene)|ensembl:ENST00000265651(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007474(ApaG)|interpro:IPR018958|interpro:IPR028388|interpro:IPR036047|interpro:IPR036767|interpro:IPR037883|rcsb pdb:5HDW|uniprotkb:Q9UK99(identity)|refseq:NM_012175(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 477 nucleotides long and that maps to nucleotides 853 to 1330 of the RefSeq entry NM_012175.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:zQB8ig3s51tXN81NtMrou84Rv6I9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:BC865FBC51AE3BAB|rigid:k+5eNS0tZnyPtBVK8DO8KYH+ajk	false	sufficient binding region:?-?	sufficient binding region:1-200	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02675	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-1034445|uniprotkb:A0JLR9|uniprotkb:Q32Q65|uniprotkb:Q3KPF2|uniprotkb:B2R7G3|ensembl:ENSP00000306099	intact:EBI-6858501|intact:EBI-6927943	psi-mi:fibb_human(display_long)|uniprotkb:FGB(gene name)|psi-mi:FGB(display_short)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929071|imex:IM-21137-79	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171670.1|refseq:NP_005132.2|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:P02675|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|ensembl:ENSG00000171564(gene)|ensembl:ENST00000302068(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|reactome:R-HSA-6802948|dip:DIP-385N|uniprotkb:P02675(identity)|refseq:NM_005141(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 843 nucleotides long and that maps to nucleotides 106 to 949 of the RefSeq entry NM_005141.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:cbcOBnZB/W/Y7eE/IxM2HfZHpK49606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:27C2BE4ABACA6513|rigid:cMEkOQvWJ0mqTnM7IIocETTHggE	false	sufficient binding region:?-?	sufficient binding region:135-631	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86YP4	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-726224|uniprotkb:Q7L3J2|uniprotkb:Q96F28|uniprotkb:Q9NPU2|uniprotkb:Q9NXS1|uniprotkb:B5MC40|ensembl:ENSP00000351552|ensembl:ENSP00000353463	intact:EBI-6858501|intact:EBI-6927943	psi-mi:p66a_human(display_long)|uniprotkb:GATA zinc finger domain-containing protein 2A(gene name synonym)|uniprotkb:GATAD2A(gene name)|psi-mi:GATAD2A(display_short)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929086|imex:IM-21137-80	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060130.3|refseq:NP_001287875.1|refseq:XP_011526407.1|ensembl:ENSG00000167491(gene)|ensembl:ENST00000358713(transcript)|ensembl:ENST00000360315(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q86YP4|rcsb pdb:2L2L|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|dip:DIP-36053N|uniprotkb:Q86YP4(identity)|refseq:NM_017660(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 689 nucleotides long and that maps to nucleotides 137 to 826 of the RefSeq entry NM_017660.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:s2G27yMihH9d7ny/v1GZ7aeTpDQ9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:EDF051FF164F6212|rigid:fyeegFUJFt9O9aKWJnVTfwvtMrU	false	sufficient binding region:?-?	sufficient binding region:135-631	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11142	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	intact:EBI-6858501|intact:EBI-6927943	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929101|imex:IM-21137-81	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N|uniprotkb:P11142(identity)|refseq:NM_006597(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 770 nucleotides long and that maps to nucleotides 886 to 1656 of the RefSeq entry NM_006597.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:FF3488119E37D67F|rigid:OTUmQ7exxlT3U8OgKHbNLLZdXeI	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:Q9NZM3	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-308689|uniprotkb:O95062|uniprotkb:Q15812|uniprotkb:Q9HAK4|uniprotkb:Q9NXE6|uniprotkb:Q9NYG0|uniprotkb:Q9NZM2|uniprotkb:Q9ULG4|ensembl:ENSP00000347244	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:itsn2_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short)|uniprotkb:KIAA1256(gene name synonym)|uniprotkb:SH3D1B(gene name synonym)|uniprotkb:SWAP(gene name synonym)|uniprotkb:SH3 domain-containing protein 1B(gene name synonym)|uniprotkb:SH3P18(gene name synonym)|uniprotkb:SH3P18-like WASP-associated protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929114|imex:IM-21137-82	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	ensembl:ENSP00000347244|ensembl:ENST00000361999|ensembl:ENSP00000354561|ensembl:ENST00000406921|ensembl:ENSP00000384499|ensembl:ENSG00000198399(gene)|ensembl:ENST00000355123(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030154"(cell differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR027029|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|rcsb pdb:1J3T|rcsb pdb:1UDL|rcsb pdb:1UE9|rcsb pdb:1UFF|rcsb pdb:1UHF|rcsb pdb:3GF9|rcsb pdb:3JZY|rcsb pdb:4IIO|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_006268.2|refseq:NP_062541.3|refseq:NP_671494.2|uniprotkb:Q9NZM3(identity)|refseq:NM_006277(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 400 nucleotides long and that maps to nucleotides 1333 to 1733 of the RefSeq entry NM_006277.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:dxUqeWmW1uwOqgZ89UhT98/pt809606	intact-crc:FEB6999396C2397E|rigid:KS+eX+V63t0SYypjrZXMfruwpxQ	false	sufficient binding region:135-631	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75592	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596	intact:EBI-6858501|intact:EBI-6927943	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929153|imex:IM-21137-84	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055872.4|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003646(Bacterial SH3-like region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|ensembl:ENSG00000005810(gene)|ensembl:ENST00000544440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|dip:DIP-28142N|uniprotkb:O75592(identity)|refseq:NM_015057(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 530 nucleotides long and that maps to nucleotides 2058 to 2588 of the RefSeq entry NM_015057.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2018/07/05	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:A94D94F2F29D6DC1|rigid:TsCjmVNo+pIibtA7T6eHJrTZ/nc	false	sufficient binding region:?-?	sufficient binding region:1-200	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:P26927	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-6929133|uniprotkb:Q6GTN4|uniprotkb:A8MSX3|uniprotkb:Q14870|uniprotkb:Q13350|uniprotkb:A6NLA3	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:hgfl_human(display_long)|uniprotkb:D3F15S2(gene name synonym)|uniprotkb:DNF15S2(gene name synonym)|uniprotkb:HGFL(gene name synonym)|uniprotkb:Macrophage stimulatory protein(gene name synonym)|uniprotkb:Macrophage-stimulating protein(gene name synonym)|uniprotkb:MST1(gene name)|psi-mi:MST1(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929129|imex:IM-21137-83	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0010758"(regulation of macrophage chemotaxis)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR038178|interpro:IPR043504|interpro:IPR043575|rcsb pdb:2ASU|rcsb pdb:4QT8|reactome:R-HSA-8852405|refseq:NP_066278.3|mint:P26927|dip:DIP-6028N|uniprotkb:P26927(identity)|refseq:NM_020998(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 476 nucleotides long and that maps to nucleotides 1087 to 1563 of the RefSeq entry NM_020998.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:CdkibLlWSzABgjln1RQ0/wPVfTc9606	intact-crc:9DEE4E767C6FEBA0|rigid:aH+02ctBog+GCYkuSS0K/9bxi5M	false	sufficient binding region:135-631	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z406	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-355595|uniprotkb:Q5CZ75|uniprotkb:Q6XYE4|uniprotkb:Q76B62|uniprotkb:Q8WV23|uniprotkb:Q96I22|uniprotkb:Q9BT27|uniprotkb:Q9BW35|uniprotkb:Q9H882|uniprotkb:B0I1S2|ensembl:ENSP00000366169|ensembl:ENSP00000472819|uniprotkb:C3TTN4	intact:EBI-6858501|intact:EBI-6927943	psi-mi:myh14_human(display_long)|uniprotkb:MYH14(gene name)|psi-mi:MYH14(display_short)|uniprotkb:KIAA2034(gene name synonym)|uniprotkb:FP17425(orf name)|uniprotkb:Myosin heavy chain 14(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIc(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIc(gene name synonym)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929168|imex:IM-21137-85	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001070654.1|refseq:NP_001139281.1|refseq:NP_079005.3|refseq:XP_011525625.1|ensembl:ENSG00000105357(gene)|ensembl:ENST00000376970(transcript)|ensembl:ENST00000596571(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030426"(growth cone)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097513"(myosin II filament)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q7Z406|rcsb pdb:5I4E|rcsb pdb:5JLH|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|interpro:IPR002928(Myosin tail)|refseq:XP_006723449.1|dip:DIP-33170N|uniprotkb:Q7Z406(identity)|refseq:NM_001077186(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 570 nucleotides long and that maps to nucleotides 5317 to 5887 of the RefSeq entry NM_001077186.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:6aY3HPa5DIY5UadiOTTh/uSPi/M9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:859DB9FD7B6ED805|rigid:or6WKEF6jrYy3z2dpcfFmyiZ01g	false	sufficient binding region:?-?	sufficient binding region:135-631	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:Q96CV9	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929183|imex:IM-21137-86	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|uniprotkb:Q96CV9(identity)|refseq:NM_001008212(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 650 nucleotides long and that maps to nucleotides 1074 to 1724 of the RefSeq entry NM_001008212.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2018/04/06	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:3797BD1F9F50D079|rigid:MQYjhdi2MRA16FK3ew0tq8fg/+M	false	sufficient binding region:135-631	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:Q96CV9	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929198|imex:IM-21137-87	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|uniprotkb:Q96CV9(identity)|refseq:NM_001008212(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 707 nucleotides long and that maps to nucleotides 1074 to 1781 of the RefSeq entry NM_001008212.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2018/04/06	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	intact-crc:502916A2331584C8|rigid:MQYjhdi2MRA16FK3ew0tq8fg/+M	false	-	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A2RUB6	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-6929230|ensembl:ENSP00000378167|uniprotkb:Q8N949|uniprotkb:B3KWL8|uniprotkb:Q4VC34	intact:EBI-6858501|intact:EBI-6927943	psi-mi:ccd66_human(display_long)|uniprotkb:CCDC66(gene name)|psi-mi:CCDC66(display_short)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929226|imex:IM-21137-89	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0060271"(cilium assembly)|go:"GO:0090543"(Flemming body)|go:"GO:1903564"(regulation of protein localization to cilium)|interpro:IPR039183|interpro:IPR040467|ensembl:ENSG00000180376(gene)|ensembl:ENST00000394672(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0008017"(microtubule binding)|go:"GO:0030054"(cell junction)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|refseq:XP_016861723.1|refseq:XP_016861724.1|refseq:NP_001012524.4|refseq:NP_001135419.1|uniprotkb:A2RUB6(identity)|refseq:NM_001012506(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 614 nucleotides long and that maps to nucleotides 825 to 1439 of the RefSeq entry NM_001012506.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:xdbeVALrykJbDXll3yRMv/ojeMg9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:21B3899781CC0BA1|rigid:q2YnNZG+NiV04lLCACmFlZehig0	false	sufficient binding region:?-?	sufficient binding region:135-631	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:O95613	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-530012|uniprotkb:O43152|uniprotkb:Q7Z7C9|intact:EBI-28971202|ensembl:ENSP00000352572	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:pcnt_human(display_long)|uniprotkb:Pericentrin-B(gene name synonym)|uniprotkb:Kendrin(gene name synonym)|uniprotkb:PCNT(gene name)|psi-mi:PCNT(display_short)|uniprotkb:KIAA0402(gene name synonym)|uniprotkb:PCNT2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929211|imex:IM-21137-88	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	ensembl:ENSP00000352572|refseq:NP_006022.3|refseq:NP_001302458.1|ensembl:ENSG00000160299(gene)|ensembl:ENST00000359568(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|interpro:IPR019528|interpro:IPR028745|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|dip:DIP-33829N|uniprotkb:O95613(identity)|refseq:NM_006031(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 603 nucleotides long and that maps to nucleotides 2575 to 3178 of the RefSeq entry NM_006031.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:8YHnOQE3b77ocsel2oAdsqvE+js9606	intact-crc:619E39D63999CF5F|rigid:ss3jgbaUh5hVxLUmjkN4uNV8xFU	false	sufficient binding region:135-631	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045596	uniprotkb:Q96RK0	intact:EBI-6901449|intact:EBI-6927909	intact:EBI-945857|uniprotkb:Q7LGI1|uniprotkb:Q9UEG5|uniprotkb:Q9Y6T1|ensembl:ENSP00000458663	psi-mi:q99ib8-pro_0000045596(display_long)	psi-mi:cic_human(display_long)|uniprotkb:CIC(gene name)|psi-mi:CIC(display_short)|uniprotkb:KIAA0306(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929248|imex:IM-21137-90	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045596(identity)	refseq:NP_055940.3|refseq:NP_001291744.1|ensembl:ENSP00000458663|dip:DIP-49964N|ensembl:ENSG00000079432(gene)|ensembl:ENST00000575354(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0035176"(social behavior)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q96RK0|rcsb pdb:2M41|rcsb pdb:4J2J|rcsb pdb:4J2L|rcsb pdb:6JRP|rcsb pdb:6KZG|rcsb pdb:6KZH|uniprotkb:Q96RK0(identity)|refseq:NM_015125(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:384|chain-seq-end:750	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 59 nucleotides long and that maps to nucleotides 107 to 166 of the RefSeq entry NM_015125.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411	rogid:E3FWgv7mlzlumUUZ/Jke9JA+JeI9606	intact-crc:E0D43459531A4DC8|rigid:6ZrDZPWe2FODZ743PuBAXJ3HQ6k	false	sufficient binding region:264-338	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q14683	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929278|imex:IM-21137-92	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N|uniprotkb:Q14683(identity)|refseq:NM_006306(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 352 nucleotides long and that maps to nucleotides 548 to 900 of the RefSeq entry NM_006306.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606	intact-crc:6565A12A6643C512|rigid:agimNeM5EVyImAFrhBDXAYzLGAo	false	sufficient binding region:367-531	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q13464	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-876651|uniprotkb:B0YJ91|uniprotkb:Q2KHM4|uniprotkb:Q59GZ4|ensembl:ENSP00000382697	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:rock1_human(display_long)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase 1(gene name synonym)|uniprotkb:p160 ROCK-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-35(gene name synonym)|uniprotkb:ROCK1(gene name)|psi-mi:ROCK1(display_short)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase I(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929263|imex:IM-21137-91	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	refseq:NP_005397.1|dip:DIP-35645N|ensembl:ENSG00000067900(gene)|ensembl:ENST00000399799(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032059"(bleb)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051045"(negative regulation of membrane protein ectodomain proteolysis)|go:"GO:0051451"(myoblast migration)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0072518"(Rho-dependent protein serine/threonine kinase activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110061"(regulation of angiotensin-activated signaling pathway)|go:"GO:0140058"(neuron projection arborization)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1905205"(positive regulation of connective tissue replacement)|go:"GO:1990776"(response to angiotensin)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015008(Rho Binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684|interpro:IPR037310|mint:Q13464|rcsb pdb:1S1C|rcsb pdb:2ESM|rcsb pdb:2ETK|rcsb pdb:2ETR|rcsb pdb:2V55|rcsb pdb:3D9V|rcsb pdb:3NCZ|rcsb pdb:3NDM|rcsb pdb:3O0Z|rcsb pdb:3TV7|rcsb pdb:3TWJ|rcsb pdb:3V8S|rcsb pdb:4L2W|rcsb pdb:4W7P|rcsb pdb:4YVC|rcsb pdb:4YVE|rcsb pdb:5BML|rcsb pdb:5F5P|rcsb pdb:5HVU|rcsb pdb:5KKS|rcsb pdb:5KKT|rcsb pdb:5UZJ|rcsb pdb:5WNE|rcsb pdb:5WNF|rcsb pdb:5WNG|rcsb pdb:5WNH|rcsb pdb:6E9W|rcsb pdb:7JOU|reactome:R-HSA-111465|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5627117|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013407|reactome:R-HSA-9013422|reactome:R-HSA-9679191|reactome:R-HSA-9696264|uniprotkb:Q13464(identity)|refseq:NM_005406(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 633 nucleotides long and that maps to nucleotides 3242 to 3875 of the RefSeq entry NM_005406.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:1YIjRC+RHWK9pmiq8kSBFiZcll49606	intact-crc:AC18DBD48F123AEE|rigid:enQLxn/6qCZ7FsTDGxV+LZVj/g8	false	sufficient binding region:367-531	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99816	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929293|imex:IM-21137-93	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|uniprotkb:Q99816(identity)|refseq:NM_006292(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 597 nucleotides long and that maps to nucleotides 535 to 1132 of the RefSeq entry NM_006292.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:B8CB2768F14B1502|rigid:73HrAESBiuABn/bXZfHbuRy9mG8	false	sufficient binding region:?-?	sufficient binding region:532-570	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46939	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929308|imex:IM-21137-94	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665|uniprotkb:P46939(identity)|refseq:NM_007124(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 750 nucleotides long and that maps to nucleotides 1049 to 1799 of the RefSeq entry NM_007124.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:metWqbqGtzonNZ1mgNjlFrenuI89606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:5BD58CECEDE2DB64|rigid:zmOe6r1kGqC8Dry2sQtHtfwi7Ic	false	sufficient binding region:?-?	sufficient binding region:532-570	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q9Y2W2	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929323|imex:IM-21137-95	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045603(identity)	rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1|uniprotkb:Q9Y2W2(identity)|refseq:NM_016312(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 728 nucleotides long and that maps to nucleotides 563 to 1291 of the RefSeq entry NM_016312.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	intact-crc:5045D9BAE08F0D9B|rigid:ayiqrF0xquhWsp4cZnj2/cf4O8g	false	sufficient binding region:1-400	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045592	uniprotkb:P04114	intact:EBI-6858513|intact:EBI-6929338	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242	psi-mi:q99ib8-pro_0000045592(display_long)	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929340|imex:IM-21137-96	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045592(identity)	refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N|uniprotkb:P04114(identity)|refseq:NM_000384.2(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2|chain-seq-end:191	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 679 nucleotides long and that maps to nucleotides 12974 to 13653 of the RefSeq entry NM_000384.2.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411	rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606	intact-crc:522EB36F1FD8A24A|rigid:ngD6QHtM9TX6olKTsRxVuGqkYwo	false	sufficient binding region:40-117	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045592	uniprotkb:Q9Y262	intact:EBI-6858513|intact:EBI-6929338	intact:EBI-373519|uniprotkb:Q53HQ1|uniprotkb:Q53HT4|uniprotkb:Q5QTR1|uniprotkb:Q5TI15|uniprotkb:Q6ICD2|uniprotkb:B2RDG6|uniprotkb:B4DYB2|uniprotkb:G8JLH4|intact:EBI-10970119|ensembl:ENSP00000485663|ensembl:ENSP00000499067	psi-mi:q99ib8-pro_0000045592(display_long)	psi-mi:eif3l_human(display_long)|uniprotkb:EIF3L(gene name)|psi-mi:EIF3L(display_short)|uniprotkb:HSPC021(orf name)|uniprotkb:HSPC025(orf name)|uniprotkb:EIF3S6IP(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6-interacting protein(gene name synonym)|uniprotkb:MSTP005(orf name)|uniprotkb:EIF3EIP(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit E-interacting protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929370|imex:IM-21137-98	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045592(identity)	refseq:NP_057175.1|refseq:NP_001229852.1|dip:DIP-31172N|ensembl:ENSG00000100129(gene)|ensembl:ENST00000624234(transcript)|ensembl:ENST00000652021(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019382|mint:Q9Y262|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|uniprotkb:Q9Y262(identity)|refseq:NM_016091.2(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2|chain-seq-end:191	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 534 nucleotides long and that maps to nucleotides 448 to 982 of the RefSeq entry NM_016091.2.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411	rogid:C9ES0WpTdEHUkjWeZK/SoDP/dAo9606	intact-crc:00324CE8F10E559C|rigid:IrEx8i/hxW1e1Vx5MCdCx7Hzftg	false	sufficient binding region:40-117	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00571	uniprotkb:Q99IB8-PRO_0000045592	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	intact:EBI-6858513|intact:EBI-6929338	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:q99ib8-pro_0000045592(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929355|imex:IM-21137-97	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N|uniprotkb:O00571(identity)|refseq:NM_001356.3(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045592(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:2|chain-seq-end:191	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 504 nucleotides long and that maps to nucleotides 2250 to 2754 of the RefSeq entry NM_001356.3.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411	intact-crc:81DBEB926535E8A8|rigid:a+gT2hRDnvsIyF8C41Xih5+WRUU	false	sufficient binding region:?-?	sufficient binding region:1-76	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86SX6	uniprotkb:Q99IB8-PRO_0000045592	intact:EBI-1049910|uniprotkb:Q3YML0|uniprotkb:Q86WY3|uniprotkb:Q8IZ54|uniprotkb:Q0X088|ensembl:ENSP00000328570	intact:EBI-6858513|intact:EBI-6929338	psi-mi:glrx5_human(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym)	psi-mi:q99ib8-pro_0000045592(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929385|imex:IM-21137-99	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057501.2|ensembl:ENSG00000182512(gene)|ensembl:ENST00000331334(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0097573"(glutathione oxidoreductase activity)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR033658|interpro:IPR036249|rcsb pdb:2MMZ|rcsb pdb:2WUL|reactome:R-HSA-1362409|dip:DIP-50654N|uniprotkb:Q86SX6(identity)|refseq:NM_016417.2(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045592(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:2|chain-seq-end:191	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 340 nucleotides long and that maps to nucleotides 228 to 568 of the RefSeq entry NM_016417.2.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:+h1VgIFt6kuH/Mc+KUxkB+w9RJI9606	rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411	intact-crc:E97D79554530DC26|rigid:jj8YDoPzjy8YVsBcRgfJ5k/bfrQ	false	sufficient binding region:?-?	sufficient binding region:40-117	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045592	uniprotkb:P06748-3	intact:EBI-6858513|intact:EBI-6929338	intact:EBI-6929404|ensembl:ENSP00000377408|ensembl:ENSP00000503235	psi-mi:q99ib8-pro_0000045592(display_long)	psi-mi:p06748-3(display_long)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929400|imex:IM-21137-100	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045592(identity)	intact:EBI-78579(isoform-parent)|ensembl:ENSG00000181163(gene)|ensembl:ENST00000393820(transcript)|ensembl:ENST00000678280(transcript)|uniprotkb:P06748-3(identity)|refseq:NM_001037738.1(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2|chain-seq-end:191	isoform-comment:Contains a N6-acetyllysine at position 257. Contains a phosphoserine at position 254.	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 333 nucleotides long and that maps to nucleotides 531 to 864 of the RefSeq entry NM_001037738.1.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411	rogid:tIbreYTCnZy+mVecCqrsajnlWO09606	intact-crc:08CD3871A552D978|rigid:l9cMJBFUrEksxoCkVQVk7nkupEw	false	sufficient binding region:1-76	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045592	uniprotkb:Q969X0	intact:EBI-6858513|intact:EBI-6929338	intact:EBI-717552|ensembl:ENSP00000280571	psi-mi:q99ib8-pro_0000045592(display_long)	psi-mi:ripl2_human(display_long)|uniprotkb:Rab-interacting lysosomal protein-like 2(gene name synonym)|uniprotkb:p40phox-binding protein(gene name synonym)|uniprotkb:RILPL2(gene name)|psi-mi:RILPL2(display_short)|uniprotkb:RLP2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929419|imex:IM-21137-101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045592(identity)	refseq:NP_659495.1|ensembl:ENSG00000150977(gene)|ensembl:ENST00000280571(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060271"(cilium assembly)|go:"GO:1903445"(protein transport from ciliary membrane to plasma membrane)|interpro:IPR021563|interpro:IPR034743|interpro:IPR034744|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:7LWB|uniprotkb:Q969X0(identity)|refseq:NM_145058.1(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:2|chain-seq-end:191	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 630 nucleotides long and that maps to nucleotides 258 to 888 of the RefSeq entry NM_145058.1.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411	rogid:Sp67YMUXLQ+A9uXKbUW5orzJ/GQ9606	intact-crc:CB8D67B4B1CFE334|rigid:Iow5z0gTt9FvPdUJyxxn93FIFGI	false	sufficient binding region:40-117	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15643	uniprotkb:Q99IB8-PRO_0000045592	intact:EBI-1047183|uniprotkb:O14689|uniprotkb:O15154|uniprotkb:O95949|uniprotkb:B2RUT2|uniprotkb:Q6MZL5|ensembl:ENSP00000267622	intact:EBI-6858513|intact:EBI-6929338	psi-mi:tripb_human(display_long)|uniprotkb:Golgi-associated microtubule-binding protein 210(gene name synonym)|uniprotkb:Clonal evolution-related gene on chromosome 14 protein(gene name synonym)|uniprotkb:Trip230(gene name synonym)|uniprotkb:TRIP11(gene name)|psi-mi:TRIP11(display_short)|uniprotkb:CEV14(gene name synonym)	psi-mi:q99ib8-pro_0000045592(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929434|imex:IM-21137-102	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004230.2|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006486"(protein glycosylation)|ensembl:ENSG00000100815(gene)|ensembl:ENST00000267622(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002079"(inner acrosomal membrane)|go:"GO:0002081"(outer acrosomal membrane)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003413"(chondrocyte differentiation involved in endochondral bone morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0030133"(transport vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0051216"(cartilage development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0099041"(vesicle tethering to Golgi)|interpro:IPR000237(GRIP)|mint:Q15643|reactome:R-HSA-5620924|reactome:R-HSA-6811438|reactome:R-HSA-9703465|ensembl:ENSP00000267622|dip:DIP-40357N|uniprotkb:Q15643(identity)|refseq:NM_004239.2(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045592(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:2|chain-seq-end:191	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 673 nucleotides long and that maps to nucleotides 4975 to 5648 of the RefSeq entry NM_004239.2.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:M/XOdT1ZPDaQqMuBXsAB5p6N9LY9606	rogid:IvCIliS0Wa+ryvS2l1H9PDAun94356411	intact-crc:849448AD39DDCC31|rigid:bXfDJmB+icR5eGbvtophYLUw99U	false	sufficient binding region:?-?	sufficient binding region:1-76	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43716	uniprotkb:Q99IB8-PRO_0000045598	intact:EBI-6929453|ensembl:ENSP00000446872|uniprotkb:B3KSU7|uniprotkb:Q3KNR8|uniprotkb:Q3B824	intact:EBI-6901421|intact:EBI-6928831	psi-mi:gatc_human(display_long)|uniprotkb:15E1.2(gene name synonym)|uniprotkb:Protein 15E1.2(gene name synonym)|uniprotkb:GATC(gene name)|psi-mi:GATC(display_short)	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929449|imex:IM-21137-103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000257218(gene)|ensembl:ENST00000551765(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0030956"("glutamyl-tRNA(Gln) amidotransferase complex")|go:"GO:0032543"(mitochondrial translation)|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0070681"(glutaminyl-tRNAGln biosynthesis via transamidation)|interpro:IPR003837(Glu-tRNAGln amidotransferase, C subunit)|interpro:IPR036113|refseq:NP_789788.1|dip:DIP-48969N|uniprotkb:O43716(identity)|refseq:NM_176818(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:814|chain-seq-end:1030	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 405 nucleotides long and that maps to nucleotides 1 to 406 of the RefSeq entry NM_176818.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:m/QzCxZNBt9yKuHTOG/qxQw1mL89606	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	intact-crc:B2194565B228A944|rigid:T0xG3Uy08TpjOPGxw95KMa/L7m8	false	sufficient binding region:?-?	sufficient binding region:100-217	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045596	uniprotkb:P08603	intact:EBI-6901449|intact:EBI-6927909	intact:EBI-1223708|uniprotkb:A5PL14|uniprotkb:Q2TAZ5|uniprotkb:P78435|uniprotkb:Q14570|uniprotkb:Q38G77|uniprotkb:Q5TFM3|uniprotkb:Q8N708|uniprotkb:Q9NU86|ensembl:ENSP00000356399	psi-mi:q99ib8-pro_0000045596(display_long)	psi-mi:cfah_human(display_long)|uniprotkb:CFH(gene name)|psi-mi:CFH(display_short)|uniprotkb:HF(gene name synonym)|uniprotkb:HF1(gene name synonym)|uniprotkb:HF2(gene name synonym)|uniprotkb:H factor 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929471|imex:IM-21137-104	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045596(identity)	refseq:NP_000177.2|dip:DIP-38303N|ensembl:ENSG00000000971(gene)|ensembl:ENST00000367429(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|mint:P08603|rcsb pdb:1FHC|rcsb pdb:1HAQ|rcsb pdb:1HCC|rcsb pdb:1HFH|rcsb pdb:1HFI|rcsb pdb:1KOV|rcsb pdb:2QFH|rcsb pdb:2RLP|rcsb pdb:2RLQ|rcsb pdb:2UWN|rcsb pdb:2V8E|rcsb pdb:2W80|rcsb pdb:2BZM|rcsb pdb:2G7I|rcsb pdb:2W81|rcsb pdb:2WII|rcsb pdb:2XQW|rcsb pdb:3GAU|rcsb pdb:3GAV|rcsb pdb:3GAW|rcsb pdb:3KXV|rcsb pdb:3KZJ|rcsb pdb:3OXU|rcsb pdb:3R62|rcsb pdb:3RJ3|rcsb pdb:3SW0|rcsb pdb:4AYD|rcsb pdb:4AYE|rcsb pdb:4AYI|rcsb pdb:4AYM|rcsb pdb:4B2R|rcsb pdb:4B2S|rcsb pdb:2IC4|rcsb pdb:2JGW|rcsb pdb:2JGX|rcsb pdb:4J38|rcsb pdb:4K12|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:2KMS|rcsb pdb:2QFG|rcsb pdb:5WTB|rcsb pdb:6ATG|reactome:R-HSA-977606|uniprotkb:P08603(identity)|refseq:NM_000186(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:384|chain-seq-end:750	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 384 nucleotides long and that maps to nucleotides 949 to 1333 of the RefSeq entry NM_000186.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411	rogid:1mjo+AJLIQnEsMFqsGsmUFbfUxk9606	intact-crc:E11CA88D99BC7DC1|rigid:zKN4rTysxuKUkK/m5DT3KtC2ifI	false	sufficient binding region:1-234	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:Q15084	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-1043087|uniprotkb:Q6ZSH5|ensembl:ENSP00000272227|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929486|imex:IM-21137-105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045599(identity)	refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|interpro:IPR036249|interpro:IPR044569|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|interpro:IPR017937|ensembl:ENSG00000143870(gene)|ensembl:ENST00000272227(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005733.1|uniprotkb:Q15084(identity)|refseq:NM_005742(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 581 nucleotides long and that maps to nucleotides 189 to 770 of the RefSeq entry NM_005742.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:411bo7TdfeCtMvUqyBb7bofi5To9606	intact-crc:C3B3BC367810F105|rigid:6FZvHE2A85YhobzAHAZdzzE8rmQ	false	sufficient binding region:135-631	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045596	uniprotkb:Q4ZG55	intact:EBI-6901449|intact:EBI-6927909	intact:EBI-6929505|uniprotkb:Q9H2Q8|uniprotkb:A6NKN0|uniprotkb:Q9H2Q7|uniprotkb:O60321|uniprotkb:Q9H2Q6|uniprotkb:Q7Z5S2|uniprotkb:B5MDA9|uniprotkb:A6NHD0|ensembl:ENSP00000234142|ensembl:ENSP00000370896	psi-mi:q99ib8-pro_0000045596(display_long)	psi-mi:greb1_human(display_long)|uniprotkb:Gene regulated in breast cancer 1 protein(gene name synonym)|uniprotkb:KIAA0575(gene name synonym)|uniprotkb:GREB1(gene name)|psi-mi:GREB1(display_short)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929501|imex:IM-21137-106	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045596(identity)	refseq:XP_011508725.1|ensembl:ENSP00000234142|ensembl:ENST00000263834|ensembl:ENSP00000263834|ensembl:ENST00000381483|ensembl:ENSP00000370892|ensembl:ENSP00000370896|ensembl:ENST00000396123|ensembl:ENSP00000379429|refseq:XP_005246249.1|refseq:NP_055483.2|refseq:NP_149081.1|refseq:NP_683701.2|ensembl:ENSG00000196208(gene)|ensembl:ENST00000234142(transcript)|ensembl:ENST00000381486(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028422|reactome:R-HSA-9018519|uniprotkb:Q4ZG55(identity)|refseq:NM_014668(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:384|chain-seq-end:750	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 274 nucleotides long and that maps to nucleotides 7209 to 7483 of the RefSeq entry NM_014668.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411	rogid:DEwyOH0KFHwtVUp1LET0LwABfH09606	intact-crc:88486A513E9BBE58|rigid:Ik9ecTSArXzI/XIgYzySOxIVOTM	false	sufficient binding region:1-234	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045596	uniprotkb:P04196	intact:EBI-6901449|intact:EBI-6927909	intact:EBI-3915012|uniprotkb:B9EK35|uniprotkb:D3DNU7|ensembl:ENSP00000232003	psi-mi:q99ib8-pro_0000045596(display_long)	psi-mi:hrg_human(display_long)|uniprotkb:HRG(gene name)|psi-mi:HRG(display_short)|uniprotkb:Histidine-proline-rich glycoprotein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929529|imex:IM-21137-107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045596(identity)	refseq:NP_000403.1|ensembl:ENSG00000113905(gene)|ensembl:ENST00000232003(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002839"(positive regulation of immune response to tumor cell)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015886"(heme transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0020037"(heme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0036019"(endolysosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000504"(positive regulation of blood vessel remodeling)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|mint:P04196|reactome:R-HSA-114608|reactome:R-HSA-75205|go:"GO:0043254"(regulation of protein-containing complex assembly)|dip:DIP-47264N|uniprotkb:P04196(identity)|refseq:NM_000412(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:384|chain-seq-end:750	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 655 nucleotides long and that maps to nucleotides 845 to 1500 of the RefSeq entry NM_000412.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411	rogid:o/MnMkd+IKLRtprrFoOapUuoVEs9606	intact-crc:F7AB9965E17DBB70|rigid:NYwU7Fq6I5A5P8jaXFAIoYsWLVU	false	sufficient binding region:1-234	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14543	uniprotkb:Q99IB8-PRO_0000045596	intact:EBI-2828729|uniprotkb:Q86XD7|uniprotkb:Q5TAF3|uniprotkb:Q5TAF2|uniprotkb:Q14942|uniprotkb:Q59FL2|ensembl:ENSP00000264187	intact:EBI-6901449|intact:EBI-6927909	psi-mi:nid1_human(display_long)|uniprotkb:NID1(gene name)|psi-mi:NID1(display_short)|uniprotkb:NID(gene name synonym)|uniprotkb:Entactin(gene name synonym)	psi-mi:q99ib8-pro_0000045596(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929559|imex:IM-21137-109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002499.2|ensembl:ENSG00000116962(gene)|ensembl:ENST00000264187(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0043236"(laminin binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071711"(basement membrane organization)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003886(Nidogen, extracellular region)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR024731|interpro:IPR026823|interpro:IPR036857|rcsb pdb:1NDX|reactome:R-HSA-1474228|reactome:R-HSA-3000157|uniprotkb:P14543(identity)|refseq:NM_002508(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045596(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:384|chain-seq-end:750	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 242 nucleotides long and that maps to nucleotides 2579 to 2821 of the RefSeq entry NM_002508.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:xlqES3FTQirfYhb0lB7RfGpFQms9606	rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411	intact-crc:7ED35D3438AFDB33|rigid:WreVpbm06Wg3hh2VQy0Ohop7eHM	false	sufficient binding region:?-?	sufficient binding region:1-234	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045596	uniprotkb:Q92802	intact:EBI-6901449|intact:EBI-6927909	intact:EBI-2514973|uniprotkb:A3KME8|ensembl:ENSP00000267068|ensembl:ENSP00000501416|ensembl:ENSP00000501516|ensembl:ENSP00000501518|ensembl:ENSP00000501537	psi-mi:q99ib8-pro_0000045596(display_long)	psi-mi:n42l2_human(display_long)|uniprotkb:N4BP2L2(gene name)|psi-mi:N4BP2L2(display_short)|uniprotkb:CG005(gene name synonym)|uniprotkb:PFAAP5(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 5(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929544|imex:IM-21137-108	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045596(identity)	refseq:XP_016875836.1|refseq:XP_016875837.1|refseq:XP_016875838.1|refseq:NP_055702.1|ensembl:ENSG00000244754(gene)|ensembl:ENST00000267068(transcript)|ensembl:ENST00000674349(transcript)|ensembl:ENST00000674421(transcript)|ensembl:ENST00000674465(transcript)|ensembl:ENST00000674484(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001824"(blastocyst development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902035"(positive regulation of hematopoietic stem cell proliferation)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|interpro:IPR026302|interpro:IPR026568|interpro:IPR027417|mint:Q92802|uniprotkb:Q92802(identity)|refseq:NM_014887(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:384|chain-seq-end:750	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 456 nucleotides long and that maps to nucleotides 835 to 1291 of the RefSeq entry NM_014887.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411	rogid:a7wRNCzoB/ImcDT7U8E5355qX1A9606	intact-crc:62798350B6BF8410|rigid:1iOe5L2ZYvYqTE7+lH2/k2tFcdU	false	sufficient binding region:1-234	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q969X0	uniprotkb:Q99IB8-PRO_0000045596	intact:EBI-717552|ensembl:ENSP00000280571	intact:EBI-6901449|intact:EBI-6927909	psi-mi:ripl2_human(display_long)|uniprotkb:Rab-interacting lysosomal protein-like 2(gene name synonym)|uniprotkb:p40phox-binding protein(gene name synonym)|uniprotkb:RILPL2(gene name)|psi-mi:RILPL2(display_short)|uniprotkb:RLP2(gene name synonym)	psi-mi:q99ib8-pro_0000045596(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929574|imex:IM-21137-110	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659495.1|ensembl:ENSG00000150977(gene)|ensembl:ENST00000280571(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060271"(cilium assembly)|go:"GO:1903445"(protein transport from ciliary membrane to plasma membrane)|interpro:IPR021563|interpro:IPR034743|interpro:IPR034744|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:7LWB|uniprotkb:Q969X0(identity)|refseq:NM_145058.1(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045596(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:384|chain-seq-end:750	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 630 nucleotides long and that maps to nucleotides 258 to 888 of the RefSeq entry NM_145058.1.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:Sp67YMUXLQ+A9uXKbUW5orzJ/GQ9606	rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411	intact-crc:6B98544BD8019038|rigid:2S6UZ+OShKDK53lXyxqUvrZ0sj8	false	sufficient binding region:?-?	sufficient binding region:1-234	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14683	uniprotkb:Q99IB8-PRO_0000045596	intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228	intact:EBI-6901449|intact:EBI-6927909	psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym)	psi-mi:q99ib8-pro_0000045596(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929589|imex:IM-21137-111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N|uniprotkb:Q14683(identity)|refseq:NM_006306(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045596(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:384|chain-seq-end:750	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 352 nucleotides long and that maps to nucleotides 548 to 900 of the RefSeq entry NM_006306.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606	rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411	intact-crc:D0130351AE45FD56|rigid:gDa0YQiN74jFtfuWNdR7SjzR7Sc	false	sufficient binding region:?-?	sufficient binding region:264-338	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045596	uniprotkb:Q9NQB0	intact:EBI-6901449|intact:EBI-6927909	intact:EBI-924724|uniprotkb:O00185|uniprotkb:Q9NQB1|uniprotkb:Q9NQB2|uniprotkb:Q9NQB3|uniprotkb:Q9NQB4|uniprotkb:Q9NQB5|uniprotkb:Q9NQB6|uniprotkb:Q9NQB7|uniprotkb:Q9ULC2|uniprotkb:B4DRJ8|uniprotkb:B9X074|uniprotkb:C6ZRJ8|uniprotkb:C6ZRK0|uniprotkb:E2GH14|uniprotkb:E2GH19|uniprotkb:E2GH20|uniprotkb:E2GH24|uniprotkb:E2GH25|uniprotkb:E9PFH9|uniprotkb:F8W742|uniprotkb:F8W7T5|ensembl:ENSP00000348274	psi-mi:q99ib8-pro_0000045596(display_long)	psi-mi:tf7l2_human(display_long)|uniprotkb:TCF7L2(gene name)|psi-mi:TCF7L2(display_short)|uniprotkb:TCF4(gene name synonym)|uniprotkb:HMG box transcription factor 4(gene name synonym)|uniprotkb:T-cell-specific transcription factor 4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929604|imex:IM-21137-112	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045596(identity)	refseq:XP_016872081.1|refseq:XP_016872082.1|refseq:NP_001139746.1|refseq:NP_001139756.1|refseq:NP_001139755.1|refseq:XP_005270141.1|refseq:XP_005270153.1|ensembl:ENST00000352065|ensembl:ENSP00000344823|ensembl:ENST00000355717|ensembl:ENSP00000347949|ensembl:ENSP00000348274|ensembl:ENST00000369397|ensembl:ENSP00000358404|ensembl:ENST00000538897|ensembl:ENSP00000446172|ensembl:ENST00000627217|ensembl:ENSP00000486891|refseq:NP_001139758.1|refseq:NP_001185455.1|refseq:NP_001185457.1|refseq:NP_001185460.1|refseq:XP_005270160.1|dip:DIP-36236N|refseq:XP_005270146.1|ensembl:ENSG00000148737(gene)|ensembl:ENST00000355995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031016"(pancreas development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0071664"(catenin-TCF7L2 complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR024940|interpro:IPR027397|interpro:IPR036910|mint:Q9NQB0|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:2GL7|reactome:R-HSA-201722|reactome:R-HSA-3769402|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-4411364|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-8853884|reactome:R-HSA-8951430|uniprotkb:Q9NQB0(identity)|refseq:NM_030756(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:384|chain-seq-end:750	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 277 nucleotides long and that maps to nucleotides 409 to 686 of the RefSeq entry NM_030756.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411	rogid:497W27pxWi8NOaZCdsthvR8mKxU9606	intact-crc:0D36E5A89F25694E|rigid:f2hAYX0BzZBuvdMmpTmYQeNCIn8	false	sufficient binding region:264-338	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045596	uniprotkb:Q9BVG3	intact:EBI-6901449|intact:EBI-6927909	intact:EBI-6929619|ensembl:ENSP00000291416|uniprotkb:B3KVH5|uniprotkb:Q9NVG0|uniprotkb:D3DPR1|uniprotkb:B4DTE4	psi-mi:q99ib8-pro_0000045596(display_long)	psi-mi:tri62_human(display_long)|uniprotkb:TRIM62(gene name)|psi-mi:TRIM62(display_short)|uniprotkb:Tripartite motif-containing protein 62(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929626|imex:IM-21137-113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045596(identity)	ensembl:ENSG00000116525(gene)|ensembl:ENST00000291416(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1905036"(positive regulation of antifungal innate immune response)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035830|interpro:IPR043136|reactome:R-HSA-877300|refseq:NP_001317412.1|refseq:NP_060677.2|uniprotkb:Q9BVG3(identity)|refseq:NM_018207(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:384|chain-seq-end:750	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 457 nucleotides long and that maps to nucleotides 609 to 1066 of the RefSeq entry NM_018207.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411	rogid:EEHDGSdYzNB7ejLtTxYiZgXFuGA9606	intact-crc:17C3812CB3822136|rigid:gvZkyiVQQAJyEg+6bTlToNxdHuk	false	sufficient binding region:1-234	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02647	uniprotkb:Q99IB8-PRO_0000045598	intact:EBI-701692|uniprotkb:Q6LDN9|uniprotkb:Q6Q785|uniprotkb:A8K866|uniprotkb:Q9UCS8|uniprotkb:Q9UCT8|ensembl:ENSP00000236850|ensembl:ENSP00000352471|ensembl:ENSP00000364469|ensembl:ENSP00000364472	intact:EBI-6901421|intact:EBI-6928831	psi-mi:apoa1_human(display_long)|uniprotkb:APOA1(gene name)|psi-mi:APOA1(display_short)|uniprotkb:Apolipoprotein A1(gene name synonym)	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929641|imex:IM-21137-114	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000030.1|refseq:NP_001304946.1|refseq:NP_001304947.1|refseq:NP_001304950.1|dip:DIP-29619N|ensembl:ENSG00000118137(gene)|ensembl:ENST00000236850(transcript)|ensembl:ENST00000359492(transcript)|ensembl:ENST00000375320(transcript)|ensembl:ENST00000375323(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0019899"(enzyme binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051180"(vitamin transport)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070508"(cholesterol import)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:P02647|rcsb pdb:1AV1|rcsb pdb:1GW3|rcsb pdb:1GW4|rcsb pdb:1ODP|rcsb pdb:1ODQ|rcsb pdb:1ODR|rcsb pdb:2MSC|rcsb pdb:2MSD|rcsb pdb:2MSE|rcsb pdb:2N5E|rcsb pdb:3K2S|rcsb pdb:3R2P|rcsb pdb:4V6M|rcsb pdb:6CC9|rcsb pdb:6CCH|rcsb pdb:6CCX|rcsb pdb:6CLZ|rcsb pdb:6CM1|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6W4E|rcsb pdb:6W4F|rcsb pdb:7KJR|reactome:R-HSA-114608|reactome:R-HSA-1369062|reactome:R-HSA-1989781|reactome:R-HSA-2168880|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-381426|reactome:R-HSA-5682113|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963896|reactome:R-HSA-8963901|reactome:R-HSA-8964011|reactome:R-HSA-8964058|reactome:R-HSA-9707616|reactome:R-HSA-975634|reactome:R-HSA-977225|uniprotkb:P02647(identity)|refseq:NM_000039(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:814|chain-seq-end:1030	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 393 nucleotides long and that maps to nucleotides 422 to 815 of the RefSeq entry NM_000039.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:yEzPDeU8Uu/43dkLLOBAy6ey1vs9606	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	intact-crc:A8E9FE7E23B10EA3|rigid:Y+G4xT1JvgbMvvOwFg5ylkJDJWE	false	sufficient binding region:?-?	sufficient binding region:100-217	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045598	uniprotkb:P01024	intact:EBI-6901421|intact:EBI-6928831	intact:EBI-905851|uniprotkb:A7E236|ensembl:ENSP00000245907	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:co3_human(display_long)|uniprotkb:C3(gene name)|psi-mi:C3(display_short)|uniprotkb:CPAMD1(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929671|imex:IM-21137-116	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	refseq:NP_000055.2|dip:DIP-35180N|ensembl:ENSG00000125730(gene)|ensembl:ENST00000245907(transcript)|go:"GO:0001798"(positive regulation of type IIa hypersensitivity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001970"(positive regulation of activation of membrane attack complex)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006956"(complement activation)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0016322"(neuron remodeling)|go:"GO:0031715"(C5L2 anaphylatoxin chemotactic receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035846"(oviduct epithelium development)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1905114"(cell surface receptor signaling pathway involved in cell-cell signaling)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR035711|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|mint:P01024|rcsb pdb:1C3D|rcsb pdb:1GHQ|rcsb pdb:1W2S|rcsb pdb:2A73|rcsb pdb:2A74|rcsb pdb:2GOX|rcsb pdb:2I07|rcsb pdb:2ICE|rcsb pdb:2ICF|rcsb pdb:2NOJ|rcsb pdb:2QKI|rcsb pdb:2WII|rcsb pdb:2WIN|rcsb pdb:2WY7|rcsb pdb:2WY8|rcsb pdb:2XQW|rcsb pdb:2XWB|rcsb pdb:2XWJ|rcsb pdb:3D5R|rcsb pdb:3D5S|rcsb pdb:3G6J|rcsb pdb:3L3O|rcsb pdb:3L5N|rcsb pdb:3NMS|rcsb pdb:3OED|rcsb pdb:3OHX|rcsb pdb:3OXU|rcsb pdb:3RJ3|rcsb pdb:3T4A|rcsb pdb:4HW5|rcsb pdb:4HWJ|rcsb pdb:4I6O|rcsb pdb:4M76|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5FO7|rcsb pdb:5FO8|rcsb pdb:5FO9|rcsb pdb:5FOA|rcsb pdb:5FOB|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:6EHG|rcsb pdb:6RMT|rcsb pdb:6RMU|rcsb pdb:6RUR|rcsb pdb:6RUV|rcsb pdb:6S0B|rcsb pdb:6YO6|reactome:R-HSA-173736|reactome:R-HSA-174577|reactome:R-HSA-198933|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-418594|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9660826|reactome:R-HSA-977606|uniprotkb:P01024(identity)|refseq:NM_000064(identity)	psi-mi:"MI:0469"(intact)	chain-seq-start:814|chain-seq-end:1030	-	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 439 nucleotides long and that maps to nucleotides 1889 to 2328 of the RefSeq entry NM_000064.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	rogid:6Axa89cCPpUXFsLnd7sCurZzLYI9606	intact-crc:9FEDB587DDB5D594|rigid:WQXjFvmXcE8btkryBIHt+ksABGE	false	sufficient binding region:100-217	sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6Q788	uniprotkb:Q99IB8-PRO_0000045598	intact:EBI-3936819|uniprotkb:B0YIV9|uniprotkb:Q6UWK9|uniprotkb:Q9UBJ3|uniprotkb:Q3MIK6|ensembl:ENSP00000227665|ensembl:ENSP00000399701|ensembl:ENSP00000445002	intact:EBI-6901421|intact:EBI-6928831	psi-mi:apoa5_human(display_long)|uniprotkb:APOA5(gene name)|psi-mi:APOA5(display_short)|uniprotkb:RAP3(gene name synonym)|uniprotkb:Apolipoprotein A5(gene name synonym)|uniprotkb:Regeneration-associated protein 3(gene name synonym)|uniprotkb:UNQ411/PRO773(orf name)	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929656|imex:IM-21137-115	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008047"(enzyme activator activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008289"(lipid binding)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010902"(positive regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0015485"(cholesterol binding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0035473"(lipase binding)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050996"(positive regulation of lipid catabolic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055090"(acylglycerol homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060229"(lipase activator activity)|go:"GO:0060230"(lipoprotein lipase activator activity)|go:"GO:0070325"(lipoprotein particle receptor binding)|go:"GO:0070328"(triglyceride homeostasis)|interpro:IPR000074(Apolipoprotein A1/A4/E)|reactome:R-HSA-1989781|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-8963889|reactome:R-HSA-8963901|go:"GO:0006869"(lipid transport)|ensembl:ENSG00000110243(gene)|ensembl:ENST00000227665(transcript)|ensembl:ENST00000433069(transcript)|ensembl:ENST00000542499(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006641"(triglyceride metabolic process)|refseq:NP_001160070.1|refseq:NP_443200.2|refseq:XP_016872658.1|uniprotkb:Q6Q788(identity)|refseq:NM_052968(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:814|chain-seq-end:1030	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 381 nucleotides long and that maps to nucleotides 451 to 832 of the RefSeq entry NM_052968.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:csQ+VFmaGt/8iBV1c3fDYCjqCcI9606	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	intact-crc:0E260F6B24478A05|rigid:g2xFfZdZgkbyc6T9jPukuNdZrz0	false	sufficient binding region:?-?	sufficient binding region:100-217	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0C0L4	uniprotkb:Q99IB8-PRO_0000045598	intact:EBI-1223619|uniprotkb:P01028|uniprotkb:P78445|uniprotkb:Q13160|uniprotkb:Q13906|uniprotkb:Q14033|uniprotkb:Q14835|uniprotkb:Q5JQM8|uniprotkb:Q9NPK5|uniprotkb:Q9UIP5|uniprotkb:B0QZR6|uniprotkb:A6H8M8|uniprotkb:A6NHJ5|uniprotkb:A7E2V2|uniprotkb:B0V2C8|uniprotkb:B2RUT6|uniprotkb:B7ZVZ6|uniprotkb:Q4LE82|uniprotkb:Q5JNX2|uniprotkb:Q6P4R1|uniprotkb:Q6U2E5|uniprotkb:Q6U2E8|uniprotkb:Q6U2F0|uniprotkb:Q6U2F3|uniprotkb:Q6U2F4|uniprotkb:Q6U2F6|uniprotkb:Q6U2F8|uniprotkb:Q6U2G0|uniprotkb:Q96EG2|uniprotkb:Q96SA8|ensembl:ENSP00000388662|ensembl:ENSP00000396688|ensembl:ENSP00000372815	intact:EBI-6901421|intact:EBI-6928831	psi-mi:co4a_human(display_long)|uniprotkb:C4A(gene name)|psi-mi:C4A(display_short)|uniprotkb:CO4(gene name synonym)|uniprotkb:CPAMD2(gene name synonym)|uniprotkb:Acidic complement C4(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2(gene name synonym)	psi-mi:q99ib8-pro_0000045598(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929686|imex:IM-21137-117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009224.2|refseq:NP_001002029.3|refseq:NP_001239133.1|ensembl:ENSG00000206340(gene)|ensembl:ENSG00000227746(gene)|ensembl:ENSG00000244731(gene)|ensembl:ENST00000383325(transcript)|ensembl:ENST00000421274(transcript)|ensembl:ENST00000428956(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR036595|interpro:IPR037569|interpro:IPR040839|interpro:IPR041555|rcsb pdb:1HZF|rcsb pdb:4FXG|rcsb pdb:4FXK|rcsb pdb:4XAM|rcsb pdb:5JPM|rcsb pdb:5JPN|rcsb pdb:5JTW|reactome:R-HSA-166663|reactome:R-HSA-174577|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977606|uniprotkb:P0C0L4(identity)|refseq:NM_007293(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045598(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:814|chain-seq-end:1030	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 742 nucleotides long and that maps to nucleotides 3076 to 3818 of the RefSeq entry NM_007293.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:nLlIFlW5RCngnXASkYPGREjA/1E9606	rogid:wDqxnwGoKrkL9adV5W65GK43rW4356411	intact-crc:4E72ABE9375BD94F|rigid:xvQOawnJfIXshKVGs00pRs7zbBY	false	sufficient binding region:?-?	sufficient binding region:100-217	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8WWM7	uniprotkb:Q99IB8-PRO_0000045596	intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4	intact:EBI-6901449|intact:EBI-6927909	psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym)	psi-mi:q99ib8-pro_0000045596(display_long)	psi-mi:"MI:0018"(two hybrid)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6929701|imex:IM-21137-118	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1|uniprotkb:Q8WWM7(identity)|refseq:NM_007245(identity)	intact:EBI-6674379(chain-parent)|uniprotkb:q99ib8-PRO_0000045596(identity)	psi-mi:"MI:0469"(intact)	-	chain-seq-start:384|chain-seq-end:750	figure legend:2a and supplementary table 2|comment:The interaction was found with a prey cDNA clone that is 529 nucleotides long and that maps to nucleotides 2525 to 3054 of the RefSeq entry NM_007245.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/08/14	2014/10/16	rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606	rogid:d8l1EuWXqUdXoYmKoeOf+YKqJ4w356411	intact-crc:B205740DF035FFCB|rigid:ngfTRNNTpnyB37TAzFyz6OW8tw4	false	sufficient binding region:?-?	sufficient binding region:1-234	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q9H8Y8	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-739467|uniprotkb:Q96I74|uniprotkb:Q96K84|uniprotkb:Q9H946|uniprotkb:Q9UFW4|uniprotkb:Q53TE3|intact:EBI-28970723|uniprotkb:B4DKT0|ensembl:ENSP00000234160	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:gors2_human(display_long)|uniprotkb:GORASP2(gene name)|psi-mi:GORASP2(display_short)|uniprotkb:Golgi reassembly-stacking protein of 55 kDa(gene name synonym)|uniprotkb:p59(gene name synonym)|uniprotkb:Golgi phosphoprotein 6(gene name synonym)|uniprotkb:GOLPH6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802876|imex:IM-21137-124	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	ensembl:ENSP00000234160|refseq:NP_001188357.1|refseq:NP_056345.3|refseq:XP_006712471.1|ensembl:ENSG00000115806(gene)|ensembl:ENST00000234160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006996"(organelle organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070925"(organelle assembly)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|mint:Q9H8Y8|rcsb pdb:3RLE|rcsb pdb:4EDJ|reactome:R-HSA-162658	-	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:3a|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:xSy3HsObmteg/doer5eLoZiz+fU9606	intact-crc:BAC89719FAA0FE2E|rigid:aJaIbbAxr6pPv+LVb8SSluk9i6w	false	sufficient binding region:1-570|maltose binding protein tag:n-n|his tag:c-c	flag tag:n-n|firefly-c:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P02751	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0096"(pull down)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802810|imex:IM-21137-119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223	intact:EBI-6674379(chain-parent)	-	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:3a|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2019/10/18	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:5202A1EBC96968EB|rigid:3OgtViexC/CTBTXQ3v24iYte1bQ	false	flag tag:n-n|firefly-c:c-c	sufficient binding region:1-570|maltose binding protein tag:n-n|his tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q13129	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-958266|uniprotkb:Q14CQ1|uniprotkb:Q9NU60|ensembl:ENSP00000361857	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:rlf_human(display_long)|uniprotkb:RLF(gene name)|psi-mi:RLF(display_short)|uniprotkb:Rearranged L-myc fusion gene protein(gene name synonym)|uniprotkb:Zn-15-related protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802902|imex:IM-21137-126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	refseq:NP_036553.2|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSG00000117000(gene)|ensembl:ENST00000372771(transcript)	-	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:3a|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:nWnF2P2Bh0uPJSAL6a5//1MxOl09606	intact-crc:1929401115D988CC|rigid:3SVKGqng34QaxoUE5WtjljXcC2M	false	maltose binding protein tag:n-n|his tag:c-c|sufficient binding region:1-570	firefly-c:c-c|flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q14683	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0096"(pull down)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802850|imex:IM-21137-122	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N	intact:EBI-6674379(chain-parent)	-	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:3a|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:12C923B9D84D9760|rigid:agimNeM5EVyImAFrhBDXAYzLGAo	false	flag tag:n-n|firefly-c:c-c	maltose binding protein tag:n-n|his tag:c-c|sufficient binding region:1-570	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y2W2	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:0096"(pull down)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802863|imex:IM-21137-123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1	intact:EBI-6674379(chain-parent)	-	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:3a|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:B50438573257B314|rigid:ayiqrF0xquhWsp4cZnj2/cf4O8g	false	firefly-c:c-c|flag tag:n-n	his tag:c-c|maltose binding protein tag:n-n|sufficient binding region:1-570	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q02818	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-2622179|uniprotkb:Q7Z4J7|uniprotkb:B2RD64|uniprotkb:Q9BUR1|uniprotkb:Q15838|intact:EBI-28978015|ensembl:ENSP00000385211|ensembl:ENSP00000385923	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:nucb1_human(display_long)|uniprotkb:NUC(gene name synonym)|uniprotkb:CALNUC(gene name synonym)|uniprotkb:NUCB1(gene name)|psi-mi:NUCB1(display_short)	psi-mi:"MI:0096"(pull down)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802837|imex:IM-21137-121	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	ensembl:ENSP00000385923|ensembl:ENSP00000385211|refseq:NP_006175.2|refseq:XP_016882334.1|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0098547"(lumenal side of Golgi membrane)|go:"GO:1903533"(regulation of protein targeting)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040250|interpro:IPR040253|mint:Q02818|rcsb pdb:1SNL|reactome:R-HSA-381426|reactome:R-HSA-8957275|ensembl:ENSG00000104805(gene)|ensembl:ENST00000405315(transcript)|ensembl:ENST00000407032(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)	-	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:3a|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:exoVYPq5+NxEpgkm/gAQay/Uwuk9606	intact-crc:8FA3A83329D315D8|rigid:YSaKPvIbPqWO0JTcS5mS4ju7Ako	false	sufficient binding region:1-570|his tag:c-c|maltose binding protein tag:n-n	firefly-c:c-c|flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:O75592	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802824|imex:IM-21137-120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	refseq:NP_055872.4|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003646(Bacterial SH3-like region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|ensembl:ENSG00000005810(gene)|ensembl:ENST00000544440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|dip:DIP-28142N	-	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:3a|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2018/07/05	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	intact-crc:C513D66C9A76EF4A|rigid:Hk5Nf0lkzgyVbyjXsSsR9jUS2tM	false	his tag:c-c|maltose binding protein tag:n-n|sufficient binding region:1-570	firefly-c:c-c|flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:P11142	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802889|imex:IM-21137-125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N	-	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:3a|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:33C4E907390AB6BA|rigid:IGoO1qAdT9LSi+304NTllofVsY4	false	sufficient binding region:1-570|his tag:c-c|maltose binding protein tag:n-n	firefly-c:c-c|flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:P11142	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802940|imex:IM-21137-129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N	-	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 548 nucleotides long and that maps to nucleotides 1074 to 1622 of the RefSeq entry NM_006597.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:84D09532A43215DC|rigid:IGoO1qAdT9LSi+304NTllofVsY4	false	sufficient binding region:1-570|firefly-n:?-?	flag tag:n-n|sufficient binding region:?-?|firefly-c:c-c	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q9H8Y8	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-739467|uniprotkb:Q96I74|uniprotkb:Q96K84|uniprotkb:Q9H946|uniprotkb:Q9UFW4|uniprotkb:Q53TE3|intact:EBI-28970723|uniprotkb:B4DKT0|ensembl:ENSP00000234160	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:gors2_human(display_long)|uniprotkb:GORASP2(gene name)|psi-mi:GORASP2(display_short)|uniprotkb:Golgi reassembly-stacking protein of 55 kDa(gene name synonym)|uniprotkb:p59(gene name synonym)|uniprotkb:Golgi phosphoprotein 6(gene name synonym)|uniprotkb:GOLPH6(gene name synonym)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802946|imex:IM-21137-132	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	ensembl:ENSP00000234160|refseq:NP_001188357.1|refseq:NP_056345.3|refseq:XP_006712471.1|ensembl:ENSG00000115806(gene)|ensembl:ENST00000234160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006996"(organelle organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070925"(organelle assembly)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|mint:Q9H8Y8|rcsb pdb:3RLE|rcsb pdb:4EDJ|reactome:R-HSA-162658|genbank identifier:NM_015530(identity)	-	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 468 nucleotides long and that maps to nucleotides 95 to 563 of the RefSeq entry NM_015530.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:xSy3HsObmteg/doer5eLoZiz+fU9606	intact-crc:CFD806F81DF6F7CA|rigid:aJaIbbAxr6pPv+LVb8SSluk9i6w	false	firefly-n:?-?|sufficient binding region:1-570	firefly-c:c-c|flag tag:n-n|sufficient binding region:?-?	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:Q96CV9	uniprotkb:Q99IB8-PRO_0000045599	intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032	intact:EBI-6858501|intact:EBI-6927943	psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym)	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8803084|imex:IM-21137-137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N|genbank identifier:NM_001008212(identity)	intact:EBI-6674379(chain-parent)	-	-	chain-seq-start:1031|chain-seq-end:1661	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 707 nucleotides long and that maps to nucleotides 1074 to 1781 of the RefSeq entry NM_001008212.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2018/04/06	rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	intact-crc:0C5CA33C21A28EAC|rigid:MQYjhdi2MRA16FK3ew0tq8fg/+M	false	sufficient binding region:?-?|flag tag:n-n|firefly-c:c-c	firefly-n:?-?	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:O75592	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802942|imex:IM-21137-130	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055872.4|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003646(Bacterial SH3-like region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|ensembl:ENSG00000005810(gene)|ensembl:ENST00000544440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|dip:DIP-28142N|genbank identifier:NM_015057(identity)	intact:EBI-6674379(chain-parent)	-	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 673 nucleotides long and that maps to nucleotides 2089 to 2762 of the RefSeq entry NM_015057.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2018/07/05	rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:75BE6E1838B6334D|rigid:Hk5Nf0lkzgyVbyjXsSsR9jUS2tM	false	sufficient binding region:?-?|flag tag:n-n|firefly-c:c-c	sufficient binding region:1-570|firefly-n:?-?	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:Q14BN4	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-1043216|ensembl:ENSP00000499241|uniprotkb:Q14C95|uniprotkb:Q6AI54|uniprotkb:Q6UXC9|uniprotkb:Q6ZVQ8|uniprotkb:Q8NCW9|uniprotkb:Q9H297|uniprotkb:Q9HCH1|uniprotkb:Q9Y681	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:slmap_human(display_long)|uniprotkb:SLMAP(gene name)|psi-mi:SLMAP(display_short)|uniprotkb:KIAA1601(gene name synonym)|uniprotkb:SLAP(gene name synonym)|uniprotkb:UNQ1847/PRO3577(orf name)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8803095|imex:IM-21137-138	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	ensembl:ENSG00000163681(gene)|ensembl:ENST00000659705(transcript)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0042383"(sarcolemma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR030498|rcsb pdb:6AKM|rcsb pdb:6AR0|rcsb pdb:6AR2|refseq:XP_016862659.1|refseq:NP_009090.2|refseq:NP_001298107.1|refseq:NP_001298108.1|refseq:NP_001291349.1|refseq:NP_001291350.1|refseq:XP_005265518.1|refseq:XP_005265523.1|refseq:XP_005265528.1|genbank identifier:NM_007159(identity)	-	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 627 nucleotides long and that maps to nucleotides 1567 to 2194 of the RefSeq entry NM_007159.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:K73SyLNTT+WZ/eE6gcjXw6yiOXQ9606	intact-crc:E0643B1947AF46D3|rigid:sUI4nf6PtuhQb5Erv8ve7oPK2Cs	false	firefly-n:?-?	sufficient binding region:?-?|flag tag:n-n|firefly-c:c-c	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:P67936	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-1642100|uniprotkb:P07226|uniprotkb:Q15659|uniprotkb:Q9BU85|uniprotkb:Q9H8Q3|uniprotkb:Q5U0D9|uniprotkb:Q9UCS1|uniprotkb:Q9UCS2|uniprotkb:Q9UCS3|uniprotkb:Q9UCS4|ensembl:ENSP00000495347	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:tpm4_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym)|uniprotkb:TM30p1(gene name synonym)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8803106|imex:IM-21137-139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	refseq:NP_001138632.1|refseq:NP_003281.1|ensembl:ENSG00000167460(gene)|ensembl:ENST00000643579(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|mint:P67936|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|genbank identifier:NM_003290(identity)	-	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 456 nucleotides long and that maps to nucleotides 242 to 698 of the RefSeq entry NM_003290.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:o8bLltMHW3vvC7Tp6YpiC0M6lkw9606	intact-crc:1D7D3F1AB16591F0|rigid:2n/CxRmJTF4h70kuVffhf5nW0yU	false	firefly-n:?-?	sufficient binding region:?-?|firefly-c:c-c|flag tag:n-n	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q14683	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802936|imex:IM-21137-127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N|genbank identifier:NM_006306(identity)	-	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 352 nucleotides long and that maps to nucleotides 548 to 900 of the RefSeq entry NM_006306.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606	intact-crc:C915CADCCEE859AF|rigid:agimNeM5EVyImAFrhBDXAYzLGAo	false	sufficient binding region:1-570|firefly-n:?-?	sufficient binding region:?-?|firefly-c:c-c|flag tag:n-n	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:P26927	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-6929133|uniprotkb:Q6GTN4|uniprotkb:A8MSX3|uniprotkb:Q14870|uniprotkb:Q13350|uniprotkb:A6NLA3	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:hgfl_human(display_long)|uniprotkb:D3F15S2(gene name synonym)|uniprotkb:DNF15S2(gene name synonym)|uniprotkb:HGFL(gene name synonym)|uniprotkb:Macrophage stimulatory protein(gene name synonym)|uniprotkb:Macrophage-stimulating protein(gene name synonym)|uniprotkb:MST1(gene name)|psi-mi:MST1(display_short)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8803073|imex:IM-21137-136	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0010758"(regulation of macrophage chemotaxis)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR038178|interpro:IPR043504|interpro:IPR043575|rcsb pdb:2ASU|rcsb pdb:4QT8|reactome:R-HSA-8852405|refseq:NP_066278.3|mint:P26927|dip:DIP-6028N|genbank identifier:NM_020998(identity)	-	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 476 nucleotides long and that maps to nucleotides 1087 to 1563 of the RefSeq entry NM_020998.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:CdkibLlWSzABgjln1RQ0/wPVfTc9606	intact-crc:DFA7C504A6006D4D|rigid:aH+02ctBog+GCYkuSS0K/9bxi5M	false	firefly-n:?-?	firefly-c:c-c|flag tag:n-n|sufficient binding region:?-?	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:P55265	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-2462104|uniprotkb:B1AQR0|uniprotkb:O15223|uniprotkb:O43859|uniprotkb:O43860|uniprotkb:Q9BYM3|uniprotkb:Q9BYM4|uniprotkb:B1AQQ9|uniprotkb:D3DV76|ensembl:ENSP00000357459	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:dsrad_human(display_long)|uniprotkb:ADAR(gene name)|psi-mi:ADAR(display_short)|uniprotkb:ADAR1(gene name synonym)|uniprotkb:DSRAD(gene name synonym)|uniprotkb:G1P1(gene name synonym)|uniprotkb:IFI4(gene name synonym)|uniprotkb:136 kDa double-stranded RNA-binding protein(gene name synonym)|uniprotkb:K88DSRBP(gene name synonym)|uniprotkb:Interferon-inducible protein 4(gene name synonym)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8803051|imex:IM-21137-134	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	refseq:NP_001020278.1|refseq:NP_001102.2|refseq:NP_001180424.1|refseq:NP_056655.2|refseq:NP_056656.2|refseq:XP_006711174.1|refseq:XP_006711175.1|refseq:XP_006711176.1|dip:DIP-29310N|ensembl:ENSG00000160710(gene)|ensembl:ENST00000368474(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002566"(somatic diversification of immune receptors via somatic mutation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008251"(tRNA-specific adenosine deaminase activity)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900369"(negative regulation of RNA interference)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371|interpro:IPR044456|interpro:IPR044457|mint:P55265|rcsb pdb:1QBJ|rcsb pdb:1QGP|rcsb pdb:1XMK|rcsb pdb:2ACJ|rcsb pdb:2GXB|rcsb pdb:2L54|rcsb pdb:2MDR|rcsb pdb:3F21|rcsb pdb:3F22|rcsb pdb:3F23|rcsb pdb:3IRQ|rcsb pdb:3IRR|rcsb pdb:5ZU1|rcsb pdb:5ZUO|rcsb pdb:5ZUP|rcsb pdb:7C0I|reactome:R-HSA-75102|reactome:R-HSA-77042|reactome:R-HSA-909733|go:"GO:0051607"(defense response to virus)|genbank identifier:NM_001025107(identity)	-	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 751 nucleotides long and that maps to nucleotides 1250 to 2001 of the RefSeq entry NM_001025107.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:rP/Yr/h8WLSFNdIuqWnYtZjZ9qI9606	intact-crc:7BE07F9787AA2A28|rigid:ky4nPTe9aCnVWMOWE4cGOpUIPfg	false	firefly-n:?-?	sufficient binding region:?-?|firefly-c:c-c|flag tag:n-n	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:Q99IB8-PRO_0000045599	uniprotkb:P11142	intact:EBI-6858501|intact:EBI-6927943	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:q99ib8-pro_0000045599(display_long)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8803062|imex:IM-21137-135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N|genbank identifier:NM_006597(identity)	-	chain-seq-start:1031|chain-seq-end:1661	-	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 770 nucleotides long and that maps to nucleotides 886 to 1656 of the RefSeq entry NM_006597.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:a8wPpxzwQPs8clBzhGspZO2pi4c356411	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:26413A3E642F7269|rigid:OTUmQ7exxlT3U8OgKHbNLLZdXeI	false	firefly-n:?-?	firefly-c:c-c|flag tag:n-n|sufficient binding region:?-?	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:Q9Y2W2	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802944|imex:IM-21137-131	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1|genbank identifier:NM_016312(identity)	intact:EBI-6674379(chain-parent)	-	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 728 nucleotides long and that maps to nucleotides 563 to 1291 of the RefSeq entry NM_016312.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:3AEC1B17DB7D6CD3|rigid:ayiqrF0xquhWsp4cZnj2/cf4O8g	false	sufficient binding region:?-?|firefly-c:c-c|flag tag:n-n	sufficient binding region:1-570|firefly-n:?-?	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:Q99IB8-PRO_0000045603	uniprotkb:Q02818	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	intact:EBI-2622179|uniprotkb:Q7Z4J7|uniprotkb:B2RD64|uniprotkb:Q9BUR1|uniprotkb:Q15838|intact:EBI-28978015|ensembl:ENSP00000385211|ensembl:ENSP00000385923	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:nucb1_human(display_long)|uniprotkb:NUC(gene name synonym)|uniprotkb:CALNUC(gene name synonym)|uniprotkb:NUCB1(gene name)|psi-mi:NUCB1(display_short)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802938|imex:IM-21137-128	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6674379(chain-parent)	ensembl:ENSP00000385923|ensembl:ENSP00000385211|refseq:NP_006175.2|refseq:XP_016882334.1|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072718"(response to cisplatin)|go:"GO:0090498"(extrinsic component of Golgi membrane)|go:"GO:0098547"(lumenal side of Golgi membrane)|go:"GO:1903533"(regulation of protein targeting)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040250|interpro:IPR040253|mint:Q02818|rcsb pdb:1SNL|reactome:R-HSA-381426|reactome:R-HSA-8957275|ensembl:ENSG00000104805(gene)|ensembl:ENST00000405315(transcript)|ensembl:ENST00000407032(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|genbank identifier:NM_006184(identity)	-	chain-seq-start:2443|chain-seq-end:3033	-	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 534 nucleotides long and that maps to nucleotides 764 to 1298 of the RefSeq entry NM_006184.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2014/10/16	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	rogid:exoVYPq5+NxEpgkm/gAQay/Uwuk9606	intact-crc:96691B88644F23DD|rigid:YSaKPvIbPqWO0JTcS5mS4ju7Ako	false	firefly-n:?-?|sufficient binding region:1-570	sufficient binding region:?-?|flag tag:n-n|firefly-c:c-c	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:P02751	uniprotkb:Q99IB8-PRO_0000045603	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:q99ib8-pro_0000045603(display_long)	psi-mi:"MI:1204"(split firefly luciferase complementation)	Dolan et al.	pubmed:24136289|doi:10.1039/C3MB70343F|imex:IM-21137	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8802948|imex:IM-21137-133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|genbank identifier:NM_212476(identity)	intact:EBI-6674379(chain-parent)	-	-	chain-seq-start:2443|chain-seq-end:3033	figure legend:3b|comment:The interaction was found with a prey cDNA clone that is 599 nucleotides long and that maps to nucleotides 6371 to 6970 of the RefSeq entry NM_212476.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/14	2019/10/18	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411	intact-crc:AEB7D533DC0B67CE|rigid:3OgtViexC/CTBTXQ3v24iYte1bQ	false	sufficient binding region:?-?|flag tag:n-n|firefly-c:c-c	sufficient binding region:1-570|firefly-n:?-?	-	-	psi-mi:"MI:1220"(tag visualisation by luciferase assay)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)