#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5T5Y3 uniprotkb:Q01082-1 intact:EBI-2837196|uniprotkb:Q96E80|uniprotkb:B2REB2|uniprotkb:Q70W33|uniprotkb:Q96FM3|uniprotkb:Q9UFJ5|uniprotkb:B2REB3|uniprotkb:Q8NCY0|uniprotkb:A1L4L2|intact:EBI-28978395|ensembl:ENSP00000374183 intact:EBI-8821722|ensembl:ENSP00000349259 psi-mi:camp1_human(display_long)|uniprotkb:CAMSAP1(gene name)|psi-mi:CAMSAP1(display_short) psi-mi:q01082-1(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym) psi-mi:"MI:0892"(solid phase assay) King et al. (2013) pubmed:24117850|imex:IM-21663 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-8821804|imex:IM-21663-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000312405|ensembl:ENSP00000312463|ensembl:ENSP00000374183|ensembl:ENST00000409386|ensembl:ENSP00000386420|refseq:NP_056262.3|refseq:XP_005263453.1|refseq:XP_005263454.1|ensembl:ENSG00000130559(gene)|ensembl:ENST00000389532(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030507"(spectrin binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0051011"(microtubule minus-end binding)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR014797(Protein of unknown function DUF1781)|interpro:IPR022613|interpro:IPR031372|interpro:IPR032940|interpro:IPR036872|interpro:IPR038209|mint:Q5T5Y3|rcsb pdb:5M54|rcsb pdb:5M5C|rcsb pdb:6QUS|rcsb pdb:6QVJ ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|intact:EBI-351561(isoform-parent) - - - figure legend:2F|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:0.65x10^-6(molar) 2013/10/24 2014/10/16 rogid:XiwTTDbfEBck/Ch8X2KYzBbPzOc9606 rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606 intact-crc:F211B9FF1092BE5D|rigid:n7vJBEbdxoIGhJbWLQlkp35+jiI false his tag:n-n|sufficient binding region:873-921 biotin tag:n-n|sufficient binding region:2149-2177 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:D3Z8E6 uniprotkb:O46391 intact:EBI-8820567|ensembl:ENSRNOP00000024163 intact:EBI-8821880 psi-mi:camp1_rat(display_long)|uniprotkb:Camsap1(gene name)|psi-mi:Camsap1(display_short) psi-mi:o46391_pig(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short) psi-mi:"MI:0107"(surface plasmon resonance) King et al. (2013) pubmed:24117850|imex:IM-21663 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-8821864|imex:IM-21663-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000017883(gene)|ensembl:ENSRNOT00000024163(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030507"(spectrin binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0051011"(microtubule minus-end binding)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR014797(Protein of unknown function DUF1781)|interpro:IPR022613|interpro:IPR031372|interpro:IPR032940|interpro:IPR036872|interpro:IPR038209|refseq:NP_001162021.1|rgd:1565022 interpro:IPR039030|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005509"(calcium ion binding)|go:"GO:0019722"(calcium-mediated signaling) - - - figure legend:3A/B|agonist:Calcium ions.|antagonist:EGTA|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:0.6x10^-6(molar) 2013/10/24 2014/10/16 rogid:+qdFry7Q9WSeyhLbQrmE5M0cWKQ10116 rogid:49hk5PBAGMBA6NThgH2O2yJv1QE9823 intact-crc:09299AFB2F94C3B5|rigid:/eSZidPveEizi9gYO+1E5sDz4tk false his tag:n-n|sufficient binding region:602-1347 biotin tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:D3Z8E6 uniprotkb:Q01082-1 intact:EBI-8820567|ensembl:ENSRNOP00000024163 intact:EBI-8821722|ensembl:ENSP00000349259 psi-mi:camp1_rat(display_long)|uniprotkb:Camsap1(gene name)|psi-mi:Camsap1(display_short) psi-mi:q01082-1(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym) psi-mi:"MI:0096"(pull down) King et al. (2013) pubmed:24117850|imex:IM-21663 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-8820565|imex:IM-21663-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000017883(gene)|ensembl:ENSRNOT00000024163(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030507"(spectrin binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0051011"(microtubule minus-end binding)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR014797(Protein of unknown function DUF1781)|interpro:IPR022613|interpro:IPR031372|interpro:IPR032940|interpro:IPR036872|interpro:IPR038209|refseq:NP_001162021.1|rgd:1565022 ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|intact:EBI-351561(isoform-parent) - - - figure legend:2B, 3D|comment:"CAMSAP1 interacts with the linker region specific to the long C-terminal variant of Beta2 Spectrin. The part of the linker specific to the long isoform is encoded by a single exon -ENSE00001306451. (corresponding to amino acids 2141-2219)"|agonist:EGTA|antagonist:Calcium ions|comment:Ca2+/calmodulin negatively regulates this interaction.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/24 2014/10/16 rogid:+qdFry7Q9WSeyhLbQrmE5M0cWKQ10116 rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606 intact-crc:C1FEBBF3309D0E8E|rigid:bNvzSvwsORhKKw7O2AIDB2XjHio false his tag:n-n|sufficient binding region:602-1347 sufficient binding region:2087-2198|necessary binding region:2140..2140-2198..2198|glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5T5Y3 uniprotkb:O46391 intact:EBI-2837196|uniprotkb:Q96E80|uniprotkb:B2REB2|uniprotkb:Q70W33|uniprotkb:Q96FM3|uniprotkb:Q9UFJ5|uniprotkb:B2REB3|uniprotkb:Q8NCY0|uniprotkb:A1L4L2|intact:EBI-28978395|ensembl:ENSP00000374183 intact:EBI-8821880 psi-mi:camp1_human(display_long)|uniprotkb:CAMSAP1(gene name)|psi-mi:CAMSAP1(display_short) psi-mi:o46391_pig(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short) psi-mi:"MI:0096"(pull down) King et al. (2013) pubmed:24117850|imex:IM-21663 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-8822082|imex:IM-21663-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000312405|ensembl:ENSP00000312463|ensembl:ENSP00000374183|ensembl:ENST00000409386|ensembl:ENSP00000386420|refseq:NP_056262.3|refseq:XP_005263453.1|refseq:XP_005263454.1|ensembl:ENSG00000130559(gene)|ensembl:ENST00000389532(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030507"(spectrin binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0051011"(microtubule minus-end binding)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR014797(Protein of unknown function DUF1781)|interpro:IPR022613|interpro:IPR031372|interpro:IPR032940|interpro:IPR036872|interpro:IPR038209|mint:Q5T5Y3|rcsb pdb:5M54|rcsb pdb:5M5C|rcsb pdb:6QUS|rcsb pdb:6QVJ interpro:IPR039030|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005509"(calcium ion binding)|go:"GO:0019722"(calcium-mediated signaling) - - - figure legend:3C|agonist:Calcium ions.|antagonist:EGTA|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/24 2014/10/16 rogid:XiwTTDbfEBck/Ch8X2KYzBbPzOc9606 rogid:49hk5PBAGMBA6NThgH2O2yJv1QE9823 intact-crc:A0AAA9D3008E5532|rigid:6/4RqrIJ0Mn9A6qXekvidgt4kd0 false sufficient binding region:903-922|biotin tag:n-n biotin tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:D3Z8E6 uniprotkb:Q6XD99 intact:EBI-8820567|ensembl:ENSRNOP00000024163 intact:EBI-2255820 psi-mi:camp1_rat(display_long)|uniprotkb:Camsap1(gene name)|psi-mi:Camsap1(display_short) psi-mi:q6xd99_rat(display_long)|uniprotkb:Sptbn1(gene name)|psi-mi:Sptbn1(display_short)|uniprotkb:Spnb2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) King et al. (2013) pubmed:24117850|imex:IM-21663 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8822201|imex:IM-21663-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000017883(gene)|ensembl:ENSRNOT00000024163(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030507"(spectrin binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0051011"(microtubule minus-end binding)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR014797(Protein of unknown function DUF1781)|interpro:IPR022613|interpro:IPR031372|interpro:IPR032940|interpro:IPR036872|interpro:IPR038209|refseq:NP_001162021.1|rgd:1565022 refseq:NP_001013148.1|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR018159|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR041681|rgd:727922|interpro:IPR036872|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098938"(actin cytoskeleton of dendritic spine)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane) - - - figure legend:3E|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2013/10/24 2014/10/16 rogid:+qdFry7Q9WSeyhLbQrmE5M0cWKQ10116 rogid:DMOrxZPtEUgn/gIfEWxOmQsIQmI10116 intact-crc:A0F6C4EAF694BF34|rigid:6k+MOzoBh819i+HtC0pR1TUz2D4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:D3Z8E6 uniprotkb:P16086 intact:EBI-8820567|ensembl:ENSRNOP00000024163 intact:EBI-2255997|uniprotkb:O88663|uniprotkb:P70477|ensembl:ENSRNOP00000042382 psi-mi:camp1_rat(display_long)|uniprotkb:Camsap1(gene name)|psi-mi:Camsap1(display_short) psi-mi:sptn1_rat(display_long)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym)|uniprotkb:Spta2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) King et al. (2013) pubmed:24117850|imex:IM-21663 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8822201|imex:IM-21663-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000017883(gene)|ensembl:ENSRNOT00000024163(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030507"(spectrin binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0051011"(microtubule minus-end binding)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR014797(Protein of unknown function DUF1781)|interpro:IPR022613|interpro:IPR031372|interpro:IPR032940|interpro:IPR036872|interpro:IPR038209|refseq:NP_001162021.1|rgd:1565022 rgd:621714|refseq:NP_741984.2|ensembl:ENSRNOG00000015396(gene)|ensembl:ENSRNOT00000045827(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0008091"(spectrin)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032437"(cuticular plate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033270"(paranode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:P16086|rcsb pdb:3THK|reactome:R-RNO-264870|reactome:R-RNO-375165|reactome:R-RNO-445095|reactome:R-RNO-5673001|reactome:R-RNO-6798695|reactome:R-RNO-6807878|reactome:R-RNO-9013420|reactome:R-RNO-9013424 - - - figure legend:3E|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2013/10/24 2014/10/16 rogid:+qdFry7Q9WSeyhLbQrmE5M0cWKQ10116 rogid:3Tj95Pgv62omEnsaMAG3bfLLXsM10116 intact-crc:A0F6C4EAF694BF34|rigid:6k+MOzoBh819i+HtC0pR1TUz2D4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)