#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P20227 uniprotkb:P40791 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-235994|uniprotkb:A1Z821|uniprotkb:Q24394|uniprotkb:Q8MT88|uniprotkb:Q95R70|uniprotkb:Q95RW1|uniprotkb:Q9U5I8|ensemblmetazoa:FBpp0087529 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:mef2_drome(display_long)|uniprotkb:Mef2(gene name)|psi-mi:Mef2(display_short)|uniprotkb:CG1429(orf name)|uniprotkb:MADS domain transcription factor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Clark et al. (2013) imex:IM-21736|pubmed:24075010 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-8870590|imex:IM-21736-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N refseq:NP_995789.1|flybase:FBgn0011656|refseq:NP_477018.1|refseq:NP_477019.1|refseq:NP_477020.1|refseq:NP_477021.1|ensemblmetazoa:FBgn0011656(gene)|ensemblmetazoa:FBtr0088443(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007496"(anterior midgut development)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019915"(lipid storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0052576"(carbohydrate storage)|go:"GO:0055001"(muscle cell development)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|reactome:R-DME-525793 - - - figure legend:Fig. 5B|comment:"In adult flies infected with the imd (CG5576) agonist E. cloacae or a mixture of M. luteus and E. coli, TBP coimmunoprecipitated with MEF2. When stimulated by E. cloacae, this association required the imd-activated JNKKK Tak1 but was unimpaired in Dif; Rel double mutants, suggesting a requirement for JNK signaling, but not NF-κB, in MEF2-TBP complex formation after Gram-negative infection"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2013/11/21 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:9pd9Vs+HYAMmYj9aHhjLMK84mfY7227 intact-crc:BC461A3A2A7BBE44|rigid:6nyfdC4jw8MGrNg1JGUqrXf/BQU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P20227 uniprotkb:P40791 intact:EBI-169179|uniprotkb:Q9W2D8|ensemblmetazoa:FBpp0071596 intact:EBI-235994|uniprotkb:A1Z821|uniprotkb:Q24394|uniprotkb:Q8MT88|uniprotkb:Q95R70|uniprotkb:Q95RW1|uniprotkb:Q9U5I8|ensemblmetazoa:FBpp0087529 psi-mi:tbp_drome(display_long)|uniprotkb:Tbp(gene name)|psi-mi:Tbp(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:CG9874(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:mef2_drome(display_long)|uniprotkb:Mef2(gene name)|psi-mi:Mef2(display_short)|uniprotkb:CG1429(orf name)|uniprotkb:MADS domain transcription factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Clark et al. (2013) imex:IM-21736|pubmed:24075010 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-8870601|imex:IM-21736-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523805.1|flybase:FBgn0003687|ensemblmetazoa:FBgn0003687(gene)|ensemblmetazoa:FBtr0071679(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042795"(snRNA transcription by RNA polymerase II)|go:"GO:0042796"(snRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|reactome:R-DME-674695|reactome:R-DME-6804756|reactome:R-DME-6807505|reactome:R-DME-73772|reactome:R-DME-73776|reactome:R-DME-73779|reactome:R-DME-75953|reactome:R-DME-76042|reactome:R-DME-76061|reactome:R-DME-76066|reactome:R-DME-9018519|dip:DIP-80N refseq:NP_995789.1|flybase:FBgn0011656|refseq:NP_477018.1|refseq:NP_477019.1|refseq:NP_477020.1|refseq:NP_477021.1|ensemblmetazoa:FBgn0011656(gene)|ensemblmetazoa:FBtr0088443(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007496"(anterior midgut development)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019915"(lipid storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0052576"(carbohydrate storage)|go:"GO:0055001"(muscle cell development)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR022102|interpro:IPR033896|interpro:IPR036879|reactome:R-DME-525793 - - - figure legend:Fig. 6D|agonist:A mixture of M. luteus and E. coli|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2013/11/21 2014/10/16 rogid:eRlX8luNoF4M7SFmEnxKSbI6FJo7227 rogid:9pd9Vs+HYAMmYj9aHhjLMK84mfY7227 intact-crc:99C1430228C97A69|rigid:6nyfdC4jw8MGrNg1JGUqrXf/BQU false - ha tag:?-?|mutation increasing interaction strength:20-20|mutation decreasing interaction strength:20-20 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)