#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q61666	uniprotkb:P84244	intact:EBI-2657552|uniprotkb:O08845|uniprotkb:Q3TFY0|uniprotkb:Q3UX35|uniprotkb:Q62365|uniprotkb:Q7TMW4|ensembl:ENSMUSP00000004222	intact:EBI-120681|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q3TW79|uniprotkb:Q3U6D6|uniprotkb:Q569U8|uniprotkb:Q5HZY8|uniprotkb:Q6TXQ5|uniprotkb:Q8VDJ2|uniprotkb:Q9D0H3|uniprotkb:Q9V3W4|ensembl:ENSMUSP00000016703|ensembl:ENSMUSP00000102062|ensembl:ENSMUSP00000124509|ensembl:ENSMUSP00000125104	psi-mi:hira_mouse(display_long)|uniprotkb:Hira(gene name)|psi-mi:Hira(display_short)|uniprotkb:Tuple1(gene name synonym)|uniprotkb:TUP1-like enhancer of split protein 1(gene name synonym)	psi-mi:h33_mouse(display_long)|uniprotkb:H3-3a(gene name)|psi-mi:H3-3a(display_short)|uniprotkb:H3-3b(gene name)|psi-mi:H3-3b(display_short)|uniprotkb:H3.3a(gene name synonym)|uniprotkb:H3.3b(gene name synonym)|uniprotkb:H3f3a(gene name synonym)|uniprotkb:H3f3b(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Banaszynski et al. (2013)	imex:IM-21728|pubmed:24074864	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8853091|imex:IM-21728-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034565.2|ensembl:ENSMUSG00000022702(gene)|ensembl:ENSMUST00000004222(transcript)|go:"GO:0000417"(HIR complex)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007369"(gastrulation)|go:"GO:0016605"(PML body)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031120|interpro:IPR036322|mint:Q61666|reactome:R-MMU-2559584	refseq:NP_032236.1|refseq:NP_032237.1|ensembl:ENSMUSG00000016559(gene)|ensembl:ENSMUSG00000060743(gene)|ensembl:ENSMUST00000016703(transcript)|ensembl:ENSMUST00000106454(transcript)|ensembl:ENSMUST00000161308(transcript)|ensembl:ENSMUST00000162814(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001740"(Barr body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006997"(nucleus organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007420"(brain development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0007286"(spermatid development)|go:"GO:0009725"(response to hormone)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:1902340"(negative regulation of chromosome condensation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84244|rcsb pdb:2RVN|rcsb pdb:5XM0|rcsb pdb:5XM1|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-9018519|reactome:R-MMU-983231|reactome:R-MMU-8936459|refseq:XP_006532311.1|dip:DIP-35190N	-	-	-	comment:Two Abs were directed against the DNA-directed RNA polymerase II subunit RPB1, one of which specifically identified the phosphorylated Ser-2'  of the tandem heptapeptide repeat n the C-terminal domain. Ubinuclein was also present in the complex but could not be ascribed to a single gene product.|figure legend:Fig. 6C, Supp. Fig. 6D|comment:In H3.3  -/- cells, the Hira-Ubinuclein interaction was maintained but association with both RNAPII and PRC2 was lost.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/11/18	2014/10/16	rogid:EhPH7DlphMVQhvIhJUtXRA1m+Fg10090	rogid:cRqA5/IBNfIbbxAnbwLqzXip20I10090	intact-crc:947B00DD1F983A43|rigid:Lh0b3AL5VsIFXTA+4cRL/xcbp68	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61666	uniprotkb:Q62315	intact:EBI-2657552|uniprotkb:O08845|uniprotkb:Q3TFY0|uniprotkb:Q3UX35|uniprotkb:Q62365|uniprotkb:Q7TMW4|ensembl:ENSMUSP00000004222	intact:EBI-493592|uniprotkb:Q99LD1|uniprotkb:Q3TPU4|uniprotkb:Q3UHS7|ensembl:ENSMUSP00000037774|ensembl:ENSMUSP00000134205|ensembl:ENSMUSP00000134675	psi-mi:hira_mouse(display_long)|uniprotkb:Hira(gene name)|psi-mi:Hira(display_short)|uniprotkb:Tuple1(gene name synonym)|uniprotkb:TUP1-like enhancer of split protein 1(gene name synonym)	psi-mi:jard2_mouse(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym)|uniprotkb:Jarid2(gene name)|psi-mi:Jarid2(display_short)|uniprotkb:Jmj(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Banaszynski et al. (2013)	imex:IM-21728|pubmed:24074864	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8853091|imex:IM-21728-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034565.2|ensembl:ENSMUSG00000022702(gene)|ensembl:ENSMUST00000004222(transcript)|go:"GO:0000417"(HIR complex)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007369"(gastrulation)|go:"GO:0016605"(PML body)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031120|interpro:IPR036322|mint:Q61666|reactome:R-MMU-2559584	refseq:NP_001191972.1|refseq:NP_001191973.1|refseq:NP_068678.1|refseq:XP_006516918.1|refseq:XP_006516919.1|refseq:XP_006516921.1|refseq:XP_006516922.1|refseq:XP_006516923.1|refseq:XP_017170888.1|ensembl:ENSMUSG00000038518(gene)|ensembl:ENSMUST00000044608(transcript)|ensembl:ENSMUST00000173246(transcript)|ensembl:ENSMUST00000173704(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q62315|rcsb pdb:2RQ5|reactome:R-MMU-212300|dip:DIP-34312N	-	-	-	comment:Two Abs were directed against the DNA-directed RNA polymerase II subunit RPB1, one of which specifically identified the phosphorylated Ser-2'  of the tandem heptapeptide repeat n the C-terminal domain. Ubinuclein was also present in the complex but could not be ascribed to a single gene product.|figure legend:Fig. 6C, Supp. Fig. 6D|comment:In H3.3  -/- cells, the Hira-Ubinuclein interaction was maintained but association with both RNAPII and PRC2 was lost.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/11/18	2014/10/16	rogid:EhPH7DlphMVQhvIhJUtXRA1m+Fg10090	rogid:ptRtfBecVfi/6SPXXxet5ycZETo10090	intact-crc:947B00DD1F983A43|rigid:Lh0b3AL5VsIFXTA+4cRL/xcbp68	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61666	uniprotkb:P08775	intact:EBI-2657552|uniprotkb:O08845|uniprotkb:Q3TFY0|uniprotkb:Q3UX35|uniprotkb:Q62365|uniprotkb:Q7TMW4|ensembl:ENSMUSP00000004222	intact:EBI-2549849|ensembl:ENSMUSP00000050771|uniprotkb:Q5F298	psi-mi:hira_mouse(display_long)|uniprotkb:Hira(gene name)|psi-mi:Hira(display_short)|uniprotkb:Tuple1(gene name synonym)|uniprotkb:TUP1-like enhancer of split protein 1(gene name synonym)	psi-mi:rpb1_mouse(display_long)|uniprotkb:Polr2a(gene name)|psi-mi:Polr2a(display_short)|uniprotkb:Rpii215(gene name synonym)|uniprotkb:Rpo2-1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Banaszynski et al. (2013)	imex:IM-21728|pubmed:24074864	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8853091|imex:IM-21728-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034565.2|ensembl:ENSMUSG00000022702(gene)|ensembl:ENSMUST00000004222(transcript)|go:"GO:0000417"(HIR complex)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007369"(gastrulation)|go:"GO:0016605"(PML body)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031120|interpro:IPR036322|mint:Q61666|reactome:R-MMU-2559584	ensembl:ENSMUSG00000005198(gene)|ensembl:ENSMUST00000058470(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|mint:P08775|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|reactome:R-MMU-112382|refseq:NP_001277997.1|dip:DIP-46369N	-	-	-	comment:Two Abs were directed against the DNA-directed RNA polymerase II subunit RPB1, one of which specifically identified the phosphorylated Ser-2'  of the tandem heptapeptide repeat n the C-terminal domain. Ubinuclein was also present in the complex but could not be ascribed to a single gene product.|figure legend:Fig. 6C, Supp. Fig. 6D|comment:In H3.3  -/- cells, the Hira-Ubinuclein interaction was maintained but association with both RNAPII and PRC2 was lost.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/11/18	2014/10/16	rogid:EhPH7DlphMVQhvIhJUtXRA1m+Fg10090	rogid:kUX/HdU6Y2VHAGjySBcOxfS08XA10090	intact-crc:947B00DD1F983A43|rigid:Lh0b3AL5VsIFXTA+4cRL/xcbp68	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61666	uniprotkb:Q80U70	intact:EBI-2657552|uniprotkb:O08845|uniprotkb:Q3TFY0|uniprotkb:Q3UX35|uniprotkb:Q62365|uniprotkb:Q7TMW4|ensembl:ENSMUSP00000004222	intact:EBI-2526494|uniprotkb:B1AQE5|uniprotkb:Q80Y10|uniprotkb:Q99L07|ensembl:ENSMUSP00000017692	psi-mi:hira_mouse(display_long)|uniprotkb:Hira(gene name)|psi-mi:Hira(display_short)|uniprotkb:Tuple1(gene name synonym)|uniprotkb:TUP1-like enhancer of split protein 1(gene name synonym)	psi-mi:suz12_mouse(display_long)|uniprotkb:Suz12(gene name)|psi-mi:Suz12(display_short)|uniprotkb:D11Ertd530e(gene name synonym)|uniprotkb:Kiaa0160(gene name synonym)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Banaszynski et al. (2013)	imex:IM-21728|pubmed:24074864	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8853091|imex:IM-21728-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034565.2|ensembl:ENSMUSG00000022702(gene)|ensembl:ENSMUST00000004222(transcript)|go:"GO:0000417"(HIR complex)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007369"(gastrulation)|go:"GO:0016605"(PML body)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031120|interpro:IPR036322|mint:Q61666|reactome:R-MMU-2559584	refseq:NP_001156490.1|refseq:NP_954666.1|ensembl:ENSMUSG00000017548(gene)|ensembl:ENSMUST00000017692(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016571"(histone methylation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR019135|mint:Q80U70|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-4551638|go:"GO:0048709"(oligodendrocyte differentiation)|reactome:R-MMU-8943724|reactome:R-MMU-8953750|dip:DIP-56045N	-	-	-	comment:Two Abs were directed against the DNA-directed RNA polymerase II subunit RPB1, one of which specifically identified the phosphorylated Ser-2'  of the tandem heptapeptide repeat n the C-terminal domain. Ubinuclein was also present in the complex but could not be ascribed to a single gene product.|figure legend:Fig. 6C, Supp. Fig. 6D|comment:In H3.3  -/- cells, the Hira-Ubinuclein interaction was maintained but association with both RNAPII and PRC2 was lost.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/11/18	2014/10/16	rogid:EhPH7DlphMVQhvIhJUtXRA1m+Fg10090	rogid:yULk8oVce1HyiORkV/CZmoSb63010090	intact-crc:947B00DD1F983A43|rigid:Lh0b3AL5VsIFXTA+4cRL/xcbp68	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)