#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B ddbj/embl/genbank:AB047639 uniprotkb:Q969R2 intact:EBI-8787654 intact:EBI-7405817|intact:EBI-11115150|uniprotkb:B4DTR3|uniprotkb:Q8NA37|uniprotkb:B4DK24|uniprotkb:F5H2A3|uniprotkb:Q9BY96|uniprotkb:Q9BZF0|uniprotkb:O60396|intact:MINT-6942148|uniprotkb:B0QYG1|ensembl:ENSP00000332576|uniprotkb:B4DKE4|uniprotkb:Q0VF99 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:osbp2_human(display_long)|uniprotkb:OSBP2(gene name)|psi-mi:OSBP2(display_short)|uniprotkb:KIAA1664(gene name synonym)|uniprotkb:ORP4(gene name synonym)|uniprotkb:OSBPL4(gene name synonym)|uniprotkb:Oxysterol-binding protein-related protein 4(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787143|imex:IM-26038-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001269667.1|refseq:NP_001269668.1|refseq:NP_001269669.1|refseq:NP_001269670.1|refseq:NP_001269671.1|refseq:NP_110385.1|refseq:XP_016884201.1|ensembl:ENSG00000184792(gene)|ensembl:ENST00000332585(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007286"(spermatid development)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097440"(apical dendrite)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239 - - function:Binds 7-ketocholesterol|comment:mint|comment:homomint figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/03 2019/01/30 - rogid:vbB6/e5IYOgFM7lxv4n1nsofLUU9606 intact-crc:3337A0555AF2D992 false sufficient binding region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:Q9HC85 intact:EBI-8787654 intact:EBI-1051258 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:q9hc85_human(display_long)|uniprotkb:MB2(gene name)|psi-mi:MB2(display_short) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787143|imex:IM-26038-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - - - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/03 2019/01/30 - rogid:yOFEQS5+h/7wJut5psRNhiIc1wk9606 intact-crc:3337A0555AF2D992 false sufficient binding region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:P22735 intact:EBI-8787654 intact:EBI-2562368|uniprotkb:Q197M4|ensembl:ENSP00000206765|ensembl:ENSP00000493587|uniprotkb:B4DWR7 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:tgm1_human(display_long)|uniprotkb:KTG(gene name synonym)|uniprotkb:Transglutaminase K(gene name synonym)|uniprotkb:Transglutaminase-1(gene name synonym)|uniprotkb:Epidermal TGase(gene name synonym)|uniprotkb:TGM1(gene name)|psi-mi:TGM1(display_short) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787143|imex:IM-26038-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_000350.1|ensembl:ENSG00000092295(gene)|ensembl:ENSG00000285348(gene)|ensembl:ENST00000206765(transcript)|ensembl:ENST00000642845(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031424"(keratinization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043163"(cell envelope organization)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|rcsb pdb:2XZZ|reactome:R-HSA-6809371 - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/03 2019/01/30 - rogid:5kr1FHRSfYLveMKchu772fNbkDM9606 intact-crc:3337A0555AF2D992 false sufficient binding region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:Q01581 intact:EBI-8787654 intact:EBI-1055448|uniprotkb:B2RDL8|ensembl:ENSP00000322706|ensembl:ENSP00000399402 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:hmcs1_human(display_long)|uniprotkb:3-hydroxy-3-methylglutaryl coenzyme A synthase(gene name synonym)|uniprotkb:HMGCS1(gene name)|psi-mi:HMGCS1(display_short)|uniprotkb:HMGCS(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787143|imex:IM-26038-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001311148.1|refseq:NP_001311149.1|refseq:NP_001311151.1|refseq:NP_001311152.1|refseq:NP_001311153.1|refseq:NP_001091742.1|refseq:NP_002121.4|ensembl:ENSG00000112972(gene)|ensembl:ENST00000325110(transcript)|ensembl:ENST00000433297(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004421"(hydroxymethylglutaryl-CoA synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0009645"(response to low light intensity stimulus)|go:"GO:0010142"(farnesyl diphosphate biosynthetic process, mevalonate pathway)|go:"GO:0014074"(response to purine-containing compound)|go:"GO:0016853"(isomerase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0033197"(response to vitamin E)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043177"(organic acid binding)|go:"GO:0046690"(response to tellurium ion)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|interpro:IPR000590(Hydroxymethylglutaryl-coenzyme A synthase, active site)|interpro:IPR010122(Hydroxymethylglutaryl-CoA synthase, eukaryotic)|interpro:IPR013528(Hydroxymethylglutaryl-coenzyme A synthase, N-terminal)|interpro:IPR013746(Hydroxymethylglutaryl-coenzyme A synthase C-terminal)|interpro:IPR016039(Thiolase-like)|mint:Q01581|rcsb pdb:2P8U|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|refseq:NP_001317592.1 - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/03 2019/01/30 - rogid:7txkOHhV1hUghX+s35oVhKsmS2c9606 intact-crc:3337A0555AF2D992 false sufficient binding region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:P63261 intact:EBI-8787654 intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787143|imex:IM-26038-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422 - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/03 2019/01/30 - rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606 intact-crc:3337A0555AF2D992 false sufficient binding region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:Q9UHL0 intact:EBI-8787654 intact:EBI-8787165|uniprotkb:B2R6Z0|uniprotkb:Q5XVN2|uniprotkb:Q86W81|uniprotkb:Q8IYP1|ensembl:ENSP00000263576 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:ddx25_human(display_long)|uniprotkb:DDX25(gene name)|psi-mi:DDX25(display_short)|uniprotkb:GRTH(gene name synonym)|uniprotkb:DEAD box protein 25(gene name synonym)|uniprotkb:Gonadotropin-regulated testicular RNA helicase(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787143|imex:IM-26038-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001317367.1|refseq:NP_037396.3|ensembl:ENSG00000109832(gene)|ensembl:ENST00000263576(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0033391"(chromatoid body)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2RB4 - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/03 2019/01/30 - rogid:+iISAA3xYBlIWU7bRvQ4DvFoMjc9606 intact-crc:3337A0555AF2D992 false sufficient binding region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:P08758 intact:EBI-8787654 intact:EBI-296601|ensembl:ENSP00000296511|uniprotkb:Q6FI16|uniprotkb:Q8WV69|uniprotkb:Q6FHB3|uniprotkb:Q9UDH9|uniprotkb:D3DNW7 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:anxa5_human(display_long)|uniprotkb:ANXA5(gene name)|psi-mi:ANXA5(display_short)|uniprotkb:ANX5(gene name synonym)|uniprotkb:ENX2(gene name synonym)|uniprotkb:PP4(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787143|imex:IM-26038-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000164111(gene)|ensembl:ENST00000296511(transcript)|go:"GO:0004859"(phospholipase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0016020"(membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050819"(negative regulation of coagulation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08758|rcsb pdb:1ANW|rcsb pdb:1ANX|rcsb pdb:1AVH|rcsb pdb:1AVR|rcsb pdb:1HAK|rcsb pdb:1HVD|rcsb pdb:1HVE|rcsb pdb:1HVF|rcsb pdb:1HVG|rcsb pdb:1SAV|rcsb pdb:2XO2|rcsb pdb:2XO3|rcsb pdb:6K22|rcsb pdb:6K25|reactome:R-HSA-114608|refseq:NP_001145.1 - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/03 2019/01/30 - rogid:vIp2wWkAz7uOtQSzbUJick5bT5o9606 intact-crc:3337A0555AF2D992 false sufficient binding region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:O75509 intact:EBI-8787654 intact:EBI-2313231|uniprotkb:B2RDI9|uniprotkb:Q0D2P5|uniprotkb:Q96D86|ensembl:ENSP00000296861 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:tnr21_human(display_long)|uniprotkb:TNFRSF21(gene name)|psi-mi:TNFRSF21(display_short)|uniprotkb:DR6(gene name synonym)|uniprotkb:Death receptor 6(gene name synonym)|uniprotkb:UNQ437/PRO868(orf name) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787143|imex:IM-26038-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_055267.1|dip:DIP-53299N|ensembl:ENSG00000146072(gene)|ensembl:ENST00000296861(transcript)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0030424"(axon)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032696"(negative regulation of interleukin-13 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042552"(myelination)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097252"(oligodendrocyte apoptotic process)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR022330|interpro:IPR034034|interpro:IPR034037|rcsb pdb:2DBH|rcsb pdb:3QO4|rcsb pdb:3U3P|rcsb pdb:3U3Q|rcsb pdb:3U3S|rcsb pdb:3U3T|rcsb pdb:3U3V|reactome:R-HSA-1989781|go:"GO:0051402"(neuron apoptotic process) - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/03 2019/01/30 - rogid:U26UBHuKo6Efzen1takNKjzhtcg9606 intact-crc:3337A0555AF2D992 false sufficient binding region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:Q14532 intact:EBI-8787654 intact:EBI-1044146|ensembl:ENSP00000225899 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:k1h2_human(display_long)|uniprotkb:KRT32(gene name)|psi-mi:KRT32(display_short)|uniprotkb:HHA2(gene name synonym)|uniprotkb:HKA2(gene name synonym)|uniprotkb:Hair keratin, type I Ha2(gene name synonym)|uniprotkb:Keratin-32(gene name synonym)|uniprotkb:KRTHA2(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787143|imex:IM-26038-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000108759(gene)|ensembl:ENST00000225899(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0008544"(epidermis development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018039|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_002269.3 - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/03 2019/01/30 - rogid:fbPhQU7W0HKcorCfIL28y6rckrc9606 intact-crc:3337A0555AF2D992 false sufficient binding region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:P11498 intact:EBI-8787654 intact:EBI-2211322|uniprotkb:Q16705|uniprotkb:B4DN00|ensembl:ENSP00000377527|ensembl:ENSP00000377530|ensembl:ENSP00000377532|ensembl:ENSP00000435905|ensembl:ENSP00000498302|ensembl:ENSP00000498406|ensembl:ENSP00000498994 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787143|imex:IM-26038-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|dip:DIP-46372N|ensembl:ENSG00000173599(gene)|ensembl:ENST00000393955(transcript)|ensembl:ENST00000393958(transcript)|ensembl:ENST00000393960(transcript)|ensembl:ENST00000529047(transcript)|ensembl:ENST00000651036(transcript)|ensembl:ENST00000651854(transcript)|ensembl:ENST00000652125(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P11498|rcsb pdb:3BG3|rcsb pdb:3BG9|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263 - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/03 2019/01/30 - rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606 intact-crc:3337A0555AF2D992 false sufficient binding region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:A8K1K1 intact:EBI-8787654 intact:EBI-8787147 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:a8k1k1_human(display_long) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787143|imex:IM-26038-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR017153(Glutathione degradosome, DUG1)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity) - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/03 2019/01/30 - rogid:thq0shT35Q5i88dbLUeq4qkfgW89606 intact-crc:3337A0555AF2D992 false sufficient binding region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:Q969R2 intact:EBI-8787654 intact:EBI-7405817|intact:EBI-11115150|uniprotkb:B4DTR3|uniprotkb:Q8NA37|uniprotkb:B4DK24|uniprotkb:F5H2A3|uniprotkb:Q9BY96|uniprotkb:Q9BZF0|uniprotkb:O60396|intact:MINT-6942148|uniprotkb:B0QYG1|ensembl:ENSP00000332576|uniprotkb:B4DKE4|uniprotkb:Q0VF99 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:osbp2_human(display_long)|uniprotkb:OSBP2(gene name)|psi-mi:OSBP2(display_short)|uniprotkb:KIAA1664(gene name synonym)|uniprotkb:ORP4(gene name synonym)|uniprotkb:OSBPL4(gene name synonym)|uniprotkb:Oxysterol-binding protein-related protein 4(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787220|imex:IM-26038-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001269667.1|refseq:NP_001269668.1|refseq:NP_001269669.1|refseq:NP_001269670.1|refseq:NP_001269671.1|refseq:NP_110385.1|refseq:XP_016884201.1|ensembl:ENSG00000184792(gene)|ensembl:ENST00000332585(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007286"(spermatid development)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097440"(apical dendrite)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239 - - function:Binds 7-ketocholesterol|comment:mint|comment:homomint figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-liver)|taxid:9606(Homo sapiens liver) - 2013/10/03 2014/10/16 - rogid:vbB6/e5IYOgFM7lxv4n1nsofLUU9606 intact-crc:CD2B7F6A0E94B7B1 false binding-associated region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:O75509 intact:EBI-8787654 intact:EBI-2313231|uniprotkb:B2RDI9|uniprotkb:Q0D2P5|uniprotkb:Q96D86|ensembl:ENSP00000296861 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:tnr21_human(display_long)|uniprotkb:TNFRSF21(gene name)|psi-mi:TNFRSF21(display_short)|uniprotkb:DR6(gene name synonym)|uniprotkb:Death receptor 6(gene name synonym)|uniprotkb:UNQ437/PRO868(orf name) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787220|imex:IM-26038-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_055267.1|dip:DIP-53299N|ensembl:ENSG00000146072(gene)|ensembl:ENST00000296861(transcript)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0030424"(axon)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032696"(negative regulation of interleukin-13 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042552"(myelination)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097252"(oligodendrocyte apoptotic process)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR022330|interpro:IPR034034|interpro:IPR034037|rcsb pdb:2DBH|rcsb pdb:3QO4|rcsb pdb:3U3P|rcsb pdb:3U3Q|rcsb pdb:3U3S|rcsb pdb:3U3T|rcsb pdb:3U3V|reactome:R-HSA-1989781|go:"GO:0051402"(neuron apoptotic process) - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-liver)|taxid:9606(Homo sapiens liver) - 2013/10/03 2014/10/16 - rogid:U26UBHuKo6Efzen1takNKjzhtcg9606 intact-crc:CD2B7F6A0E94B7B1 false binding-associated region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:P08758 intact:EBI-8787654 intact:EBI-296601|ensembl:ENSP00000296511|uniprotkb:Q6FI16|uniprotkb:Q8WV69|uniprotkb:Q6FHB3|uniprotkb:Q9UDH9|uniprotkb:D3DNW7 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:anxa5_human(display_long)|uniprotkb:ANXA5(gene name)|psi-mi:ANXA5(display_short)|uniprotkb:ANX5(gene name synonym)|uniprotkb:ENX2(gene name synonym)|uniprotkb:PP4(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787220|imex:IM-26038-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000164111(gene)|ensembl:ENST00000296511(transcript)|go:"GO:0004859"(phospholipase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0016020"(membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050819"(negative regulation of coagulation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08758|rcsb pdb:1ANW|rcsb pdb:1ANX|rcsb pdb:1AVH|rcsb pdb:1AVR|rcsb pdb:1HAK|rcsb pdb:1HVD|rcsb pdb:1HVE|rcsb pdb:1HVF|rcsb pdb:1HVG|rcsb pdb:1SAV|rcsb pdb:2XO2|rcsb pdb:2XO3|rcsb pdb:6K22|rcsb pdb:6K25|reactome:R-HSA-114608|refseq:NP_001145.1 - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-liver)|taxid:9606(Homo sapiens liver) - 2013/10/03 2014/10/16 - rogid:vIp2wWkAz7uOtQSzbUJick5bT5o9606 intact-crc:CD2B7F6A0E94B7B1 false binding-associated region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:Q9HC85 intact:EBI-8787654 intact:EBI-1051258 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:q9hc85_human(display_long)|uniprotkb:MB2(gene name)|psi-mi:MB2(display_short) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787220|imex:IM-26038-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - - - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-liver)|taxid:9606(Homo sapiens liver) - 2013/10/03 2014/10/16 - rogid:yOFEQS5+h/7wJut5psRNhiIc1wk9606 intact-crc:CD2B7F6A0E94B7B1 false binding-associated region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:A8K1K1 intact:EBI-8787654 intact:EBI-8787147 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:a8k1k1_human(display_long) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787220|imex:IM-26038-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR017153(Glutathione degradosome, DUG1)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity) - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-liver)|taxid:9606(Homo sapiens liver) - 2013/10/03 2014/10/16 - rogid:thq0shT35Q5i88dbLUeq4qkfgW89606 intact-crc:CD2B7F6A0E94B7B1 false binding-associated region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:Q9UHL0 intact:EBI-8787654 intact:EBI-8787165|uniprotkb:B2R6Z0|uniprotkb:Q5XVN2|uniprotkb:Q86W81|uniprotkb:Q8IYP1|ensembl:ENSP00000263576 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:ddx25_human(display_long)|uniprotkb:DDX25(gene name)|psi-mi:DDX25(display_short)|uniprotkb:GRTH(gene name synonym)|uniprotkb:DEAD box protein 25(gene name synonym)|uniprotkb:Gonadotropin-regulated testicular RNA helicase(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787220|imex:IM-26038-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001317367.1|refseq:NP_037396.3|ensembl:ENSG00000109832(gene)|ensembl:ENST00000263576(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006417"(regulation of translation)|go:"GO:0007286"(spermatid development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0033391"(chromatoid body)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2RB4 - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-liver)|taxid:9606(Homo sapiens liver) - 2013/10/03 2014/10/16 - rogid:+iISAA3xYBlIWU7bRvQ4DvFoMjc9606 intact-crc:CD2B7F6A0E94B7B1 false binding-associated region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:P11498 intact:EBI-8787654 intact:EBI-2211322|uniprotkb:Q16705|uniprotkb:B4DN00|ensembl:ENSP00000377527|ensembl:ENSP00000377530|ensembl:ENSP00000377532|ensembl:ENSP00000435905|ensembl:ENSP00000498302|ensembl:ENSP00000498406|ensembl:ENSP00000498994 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787220|imex:IM-26038-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|dip:DIP-46372N|ensembl:ENSG00000173599(gene)|ensembl:ENST00000393955(transcript)|ensembl:ENST00000393958(transcript)|ensembl:ENST00000393960(transcript)|ensembl:ENST00000529047(transcript)|ensembl:ENST00000651036(transcript)|ensembl:ENST00000651854(transcript)|ensembl:ENST00000652125(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P11498|rcsb pdb:3BG3|rcsb pdb:3BG9|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263 - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-liver)|taxid:9606(Homo sapiens liver) - 2013/10/03 2014/10/16 - rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606 intact-crc:CD2B7F6A0E94B7B1 false binding-associated region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:Q9HC85 intact:EBI-8787654 intact:EBI-1051258 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:q9hc85_human(display_long)|uniprotkb:MB2(gene name)|psi-mi:MB2(display_short) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787255|imex:IM-26038-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - - - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/10/03 2014/10/16 - rogid:yOFEQS5+h/7wJut5psRNhiIc1wk9606 intact-crc:000D0A71C54DDC37 false binding-associated region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) ddbj/embl/genbank:AB047639 uniprotkb:O75509 intact:EBI-8787654 intact:EBI-2313231|uniprotkb:B2RDI9|uniprotkb:Q0D2P5|uniprotkb:Q96D86|ensembl:ENSP00000296861 psi-mi:polg_hcvjf_rna(display_short)|psi-mi:AB047639(display_long) psi-mi:tnr21_human(display_long)|uniprotkb:TNFRSF21(gene name)|psi-mi:TNFRSF21(display_short)|uniprotkb:DR6(gene name synonym)|uniprotkb:Death receptor 6(gene name synonym)|uniprotkb:UNQ437/PRO868(orf name) psi-mi:"MI:0096"(pull down) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787255|imex:IM-26038-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_055267.1|dip:DIP-53299N|ensembl:ENSG00000146072(gene)|ensembl:ENST00000296861(transcript)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0030424"(axon)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032696"(negative regulation of interleukin-13 production)|go:"GO:0032714"(negative regulation of interleukin-5 production)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042552"(myelination)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097252"(oligodendrocyte apoptotic process)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR022330|interpro:IPR034034|interpro:IPR034037|rcsb pdb:2DBH|rcsb pdb:3QO4|rcsb pdb:3U3P|rcsb pdb:3U3Q|rcsb pdb:3U3S|rcsb pdb:3U3T|rcsb pdb:3U3V|reactome:R-HSA-1989781|go:"GO:0051402"(neuron apoptotic process) - - - figure legend:Fig. 2 and table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/10/03 2014/10/16 - rogid:U26UBHuKo6Efzen1takNKjzhtcg9606 intact-crc:000D0A71C54DDC37 false binding-associated region:9579-9678|biotin tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q969R2 uniprotkb:Q99IB8-PRO_0000045603 intact:EBI-7405817|intact:EBI-11115150|uniprotkb:B4DTR3|uniprotkb:Q8NA37|uniprotkb:B4DK24|uniprotkb:F5H2A3|uniprotkb:Q9BY96|uniprotkb:Q9BZF0|uniprotkb:O60396|intact:MINT-6942148|uniprotkb:B0QYG1|ensembl:ENSP00000332576|uniprotkb:B4DKE4|uniprotkb:Q0VF99 intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804 psi-mi:osbp2_human(display_long)|uniprotkb:OSBP2(gene name)|psi-mi:OSBP2(display_short)|uniprotkb:KIAA1664(gene name synonym)|uniprotkb:ORP4(gene name synonym)|uniprotkb:OSBPL4(gene name synonym)|uniprotkb:Oxysterol-binding protein-related protein 4(gene name synonym) psi-mi:q99ib8-pro_0000045603(display_long) psi-mi:"MI:0428"(imaging technique) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787282|imex:IM-26038-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269667.1|refseq:NP_001269668.1|refseq:NP_001269669.1|refseq:NP_001269670.1|refseq:NP_001269671.1|refseq:NP_110385.1|refseq:XP_016884201.1|ensembl:ENSG00000184792(gene)|ensembl:ENST00000332585(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007286"(spermatid development)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097440"(apical dendrite)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239 intact:EBI-6674379(chain-parent) go:"GO:0044165"(host cell endoplasmic reticulum) function:Binds 7-ketocholesterol|comment:mint|comment:homomint chain-seq-start:2443|chain-seq-end:3033 figure legend:Fig. 3C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/03 2017/09/02 rogid:vbB6/e5IYOgFM7lxv4n1nsofLUU9606 rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411 intact-crc:2CD25F2604330008|rigid:XydBGwqbZCEPRdfpezy+lH/r/iY false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q969R2 uniprotkb:Q99IB8-PRO_0000045603 intact:EBI-7405817|intact:EBI-11115150|uniprotkb:B4DTR3|uniprotkb:Q8NA37|uniprotkb:B4DK24|uniprotkb:F5H2A3|uniprotkb:Q9BY96|uniprotkb:Q9BZF0|uniprotkb:O60396|intact:MINT-6942148|uniprotkb:B0QYG1|ensembl:ENSP00000332576|uniprotkb:B4DKE4|uniprotkb:Q0VF99 intact:EBI-6927928|intact:EBI-8787284|intact:EBI-8792181|intact:EBI-8802804 psi-mi:osbp2_human(display_long)|uniprotkb:OSBP2(gene name)|psi-mi:OSBP2(display_short)|uniprotkb:KIAA1664(gene name synonym)|uniprotkb:ORP4(gene name synonym)|uniprotkb:OSBPL4(gene name synonym)|uniprotkb:Oxysterol-binding protein-related protein 4(gene name synonym) psi-mi:q99ib8-pro_0000045603(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Park et al. (2013) pubmed:24069433|imex:IM-26038 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:356411(hcvjf)|taxid:356411("Hepatitis C virus genotype 2a (isolate JFH-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8787305|imex:IM-26038-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269667.1|refseq:NP_001269668.1|refseq:NP_001269669.1|refseq:NP_001269670.1|refseq:NP_001269671.1|refseq:NP_110385.1|refseq:XP_016884201.1|ensembl:ENSG00000184792(gene)|ensembl:ENST00000332585(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007286"(spermatid development)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097440"(apical dendrite)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239 intact:EBI-6674379(chain-parent) - function:Binds 7-ketocholesterol|comment:mint|comment:homomint chain-seq-start:2443|chain-seq-end:3033 figure legend:Fig. 6A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/10/03 2017/09/02 rogid:vbB6/e5IYOgFM7lxv4n1nsofLUU9606 rogid:nInn2TP1wUR7XmXCn2H9IZBbKMk356411 intact-crc:ADC8CA16754099B1|rigid:XydBGwqbZCEPRdfpezy+lH/r/iY false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)