#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P01100	uniprotkb:P17275	intact:EBI-852851|uniprotkb:P18849|uniprotkb:A8K4E2|uniprotkb:B4DQ65|ensembl:ENSP00000306245	intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315	psi-mi:fos_human(display_long)|uniprotkb:Cellular oncogene fos(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 7(gene name synonym)|uniprotkb:FOS(gene name)|psi-mi:FOS(display_short)|uniprotkb:G0S7(gene name synonym)	psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784431|imex:IM-21527-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005243.1|dip:DIP-1047N|ensembl:ENSG00000170345(gene)|ensembl:ENST00000303562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009409"(response to cold)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030431"(sleep)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029816|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1S9K|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9634638	refseq:NP_002220.1|ensembl:ENSG00000171223(gene)|ensembl:ENST00000302754(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-1052N	-	-	-	figure legend:5Diii|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle)|taxid:9606(Homo sapiens)	-	2013/09/30	2014/10/16	rogid:R09jzTKeAyzIQYTQAsps2UWFyFE9606	rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606	intact-crc:269A4992DD4E78C4|rigid:5Eg6Lgd0xqjqCLrNGmBTr45mbr8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P01100	uniprotkb:P17535	intact:EBI-852851|uniprotkb:P18849|uniprotkb:A8K4E2|uniprotkb:B4DQ65|ensembl:ENSP00000306245	intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818	psi-mi:fos_human(display_long)|uniprotkb:Cellular oncogene fos(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 7(gene name synonym)|uniprotkb:FOS(gene name)|psi-mi:FOS(display_short)|uniprotkb:G0S7(gene name synonym)	psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784431|imex:IM-21527-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005243.1|dip:DIP-1047N|ensembl:ENSG00000170345(gene)|ensembl:ENST00000303562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009409"(response to cold)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030431"(sleep)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029816|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1S9K|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9634638	refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N	-	-	-	figure legend:5Diii|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle)|taxid:9606(Homo sapiens)	-	2013/09/30	2014/10/16	rogid:R09jzTKeAyzIQYTQAsps2UWFyFE9606	rogid:npmTGULvlKr4hC8HfmK19GUopf49606	intact-crc:269A4992DD4E78C4|rigid:5Eg6Lgd0xqjqCLrNGmBTr45mbr8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P15407	uniprotkb:P05412	intact:EBI-744510|ensembl:ENSP00000310170|uniprotkb:Q6FG51|uniprotkb:B4DR11	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266|ensembl:ENSP00000503132	psi-mi:fosl1_human(display_long)|uniprotkb:FOSL1(gene name)|psi-mi:FOSL1(display_short)|uniprotkb:FRA1(gene name synonym)	psi-mi:jun_human(display_long)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784417|imex:IM-21527-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005429.1|ensembl:ENSG00000175592(gene)|ensembl:ENST00000312562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006935"(chemotaxis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007296"(vitellogenesis)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0009629"(response to gravity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032570"(response to progesterone)|go:"GO:0034097"(response to cytokine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029815|reactome:R-HSA-9031628|go:"GO:0003700"(DNA-binding transcription factor activity)|refseq:NP_001287773.1|refseq:NP_001287784.1|refseq:NP_001287785.1|refseq:NP_001287786.1|dip:DIP-660N	refseq:NP_002219.1|ensembl:ENSP00000360266|ensembl:ENSP00000503132|dip:DIP-5961N|ensembl:ENSG00000177606(gene)|ensembl:ENST00000371222(transcript)|ensembl:ENST00000678696(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324	-	-	-	figure legend:5Di|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle_namec)|taxid:9606("Homo sapiens_Hmle_namec:Human  mammary epithelial cell line (immortalized)- stable  post EMT cells.")	-	2013/09/30	2014/10/16	rogid:gnUIflNG3z+k6YGqNH67g9rerVM9606	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	intact-crc:20644A61FF88332B|rigid:eDTBe0ZIVS8/6Jt4di9Ck9q3+nk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P15407	uniprotkb:P17275	intact:EBI-744510|ensembl:ENSP00000310170|uniprotkb:Q6FG51|uniprotkb:B4DR11	intact:EBI-748062|uniprotkb:Q96GH3|ensembl:ENSP00000303315	psi-mi:fosl1_human(display_long)|uniprotkb:FOSL1(gene name)|psi-mi:FOSL1(display_short)|uniprotkb:FRA1(gene name synonym)	psi-mi:junb_human(display_long)|uniprotkb:JUNB(gene name)|psi-mi:JUNB(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784417|imex:IM-21527-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005429.1|ensembl:ENSG00000175592(gene)|ensembl:ENST00000312562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006935"(chemotaxis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007296"(vitellogenesis)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0009629"(response to gravity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032570"(response to progesterone)|go:"GO:0034097"(response to cytokine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029815|reactome:R-HSA-9031628|go:"GO:0003700"(DNA-binding transcription factor activity)|refseq:NP_001287773.1|refseq:NP_001287784.1|refseq:NP_001287785.1|refseq:NP_001287786.1|dip:DIP-660N	refseq:NP_002220.1|ensembl:ENSG00000171223(gene)|ensembl:ENST00000302754(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0033687"(osteoblast proliferation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR029822|mint:P17275|reactome:R-HSA-2173796|reactome:R-HSA-6785807|reactome:R-HSA-9031628|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|dip:DIP-1052N	-	-	-	figure legend:5Di|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle_namec)|taxid:9606("Homo sapiens_Hmle_namec:Human  mammary epithelial cell line (immortalized)- stable  post EMT cells.")	-	2013/09/30	2014/10/16	rogid:gnUIflNG3z+k6YGqNH67g9rerVM9606	rogid:p2UBpMzVG+A8AV7UCH4jYTsoPF89606	intact-crc:20644A61FF88332B|rigid:eDTBe0ZIVS8/6Jt4di9Ck9q3+nk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P15407	uniprotkb:P17535	intact:EBI-744510|ensembl:ENSP00000310170|uniprotkb:Q6FG51|uniprotkb:B4DR11	intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818	psi-mi:fosl1_human(display_long)|uniprotkb:FOSL1(gene name)|psi-mi:FOSL1(display_short)|uniprotkb:FRA1(gene name synonym)	psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784417|imex:IM-21527-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005429.1|ensembl:ENSG00000175592(gene)|ensembl:ENST00000312562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006935"(chemotaxis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007296"(vitellogenesis)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0009629"(response to gravity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032570"(response to progesterone)|go:"GO:0034097"(response to cytokine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029815|reactome:R-HSA-9031628|go:"GO:0003700"(DNA-binding transcription factor activity)|refseq:NP_001287773.1|refseq:NP_001287784.1|refseq:NP_001287785.1|refseq:NP_001287786.1|dip:DIP-660N	refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N	-	-	-	figure legend:5Di|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle_namec)|taxid:9606("Homo sapiens_Hmle_namec:Human  mammary epithelial cell line (immortalized)- stable  post EMT cells.")	-	2013/09/30	2014/10/16	rogid:gnUIflNG3z+k6YGqNH67g9rerVM9606	rogid:npmTGULvlKr4hC8HfmK19GUopf49606	intact-crc:20644A61FF88332B|rigid:eDTBe0ZIVS8/6Jt4di9Ck9q3+nk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05412	uniprotkb:P15407	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266|ensembl:ENSP00000503132	intact:EBI-744510|ensembl:ENSP00000310170|uniprotkb:Q6FG51|uniprotkb:B4DR11	psi-mi:jun_human(display_long)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	psi-mi:fosl1_human(display_long)|uniprotkb:FOSL1(gene name)|psi-mi:FOSL1(display_short)|uniprotkb:FRA1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784424|imex:IM-21527-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002219.1|ensembl:ENSP00000360266|ensembl:ENSP00000503132|dip:DIP-5961N|ensembl:ENSG00000177606(gene)|ensembl:ENST00000371222(transcript)|ensembl:ENST00000678696(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324	refseq:NP_005429.1|ensembl:ENSG00000175592(gene)|ensembl:ENST00000312562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006935"(chemotaxis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007296"(vitellogenesis)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0009629"(response to gravity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032570"(response to progesterone)|go:"GO:0034097"(response to cytokine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029815|reactome:R-HSA-9031628|go:"GO:0003700"(DNA-binding transcription factor activity)|refseq:NP_001287773.1|refseq:NP_001287784.1|refseq:NP_001287785.1|refseq:NP_001287786.1|dip:DIP-660N	-	-	-	figure legend:5Dii|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle_namec)|taxid:9606("Homo sapiens_Hmle_namec:Human  mammary epithelial cell line (immortalized)- stable  post EMT cells.")	-	2013/09/30	2014/10/16	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	rogid:gnUIflNG3z+k6YGqNH67g9rerVM9606	intact-crc:17DDBC37BE8AF716|rigid:3hoegyRnMvTS/tF5Nr7ZRjdHaOc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05412	uniprotkb:P01100	intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266|ensembl:ENSP00000503132	intact:EBI-852851|uniprotkb:P18849|uniprotkb:A8K4E2|uniprotkb:B4DQ65|ensembl:ENSP00000306245	psi-mi:jun_human(display_long)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)	psi-mi:fos_human(display_long)|uniprotkb:Cellular oncogene fos(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 7(gene name synonym)|uniprotkb:FOS(gene name)|psi-mi:FOS(display_short)|uniprotkb:G0S7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784424|imex:IM-21527-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002219.1|ensembl:ENSP00000360266|ensembl:ENSP00000503132|dip:DIP-5961N|ensembl:ENSG00000177606(gene)|ensembl:ENST00000371222(transcript)|ensembl:ENST00000678696(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324	refseq:NP_005243.1|dip:DIP-1047N|ensembl:ENSG00000170345(gene)|ensembl:ENST00000303562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009409"(response to cold)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030431"(sleep)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029816|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1S9K|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9634638	-	-	-	figure legend:5Dii|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle_namec)|taxid:9606("Homo sapiens_Hmle_namec:Human  mammary epithelial cell line (immortalized)- stable  post EMT cells.")	-	2013/09/30	2014/10/16	rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606	rogid:R09jzTKeAyzIQYTQAsps2UWFyFE9606	intact-crc:17DDBC37BE8AF716|rigid:3hoegyRnMvTS/tF5Nr7ZRjdHaOc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P01100	ensembl:ENSG00000130545	intact:EBI-852851|uniprotkb:P18849|uniprotkb:A8K4E2|uniprotkb:B4DQ65|ensembl:ENSP00000306245	intact:EBI-8784483	psi-mi:fos_human(display_long)|uniprotkb:Cellular oncogene fos(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 7(gene name synonym)|uniprotkb:FOS(gene name)|psi-mi:FOS(display_short)|uniprotkb:G0S7(gene name synonym)	psi-mi:crum3_human_gene(display_short)|psi-mi:ENSG00000130545(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784489|imex:IM-21527-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_005243.1|dip:DIP-1047N|ensembl:ENSG00000170345(gene)|ensembl:ENST00000303562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009409"(response to cold)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030431"(sleep)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029816|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1S9K|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9634638	-	-	-	-	figure legend:5E|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle)|taxid:9606(Homo sapiens)	-	2013/09/30	2014/10/16	rogid:R09jzTKeAyzIQYTQAsps2UWFyFE9606	-	intact-crc:4998A974423D5E45	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000039068	uniprotkb:P01100	intact:EBI-2679244	intact:EBI-852851|uniprotkb:P18849|uniprotkb:A8K4E2|uniprotkb:B4DQ65|ensembl:ENSP00000306245	psi-mi:cadh1_human_gene(display_short)|psi-mi:ENSG00000039068(display_long)	psi-mi:fos_human(display_long)|uniprotkb:Cellular oncogene fos(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 7(gene name synonym)|uniprotkb:FOS(gene name)|psi-mi:FOS(display_short)|uniprotkb:G0S7(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784456|imex:IM-21527-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005243.1|dip:DIP-1047N|ensembl:ENSG00000170345(gene)|ensembl:ENST00000303562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009409"(response to cold)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030431"(sleep)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029816|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1S9K|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9634638	-	-	-	figure legend:5E|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle)|taxid:9606(Homo sapiens)	-	2013/09/30	2014/10/16	-	rogid:R09jzTKeAyzIQYTQAsps2UWFyFE9606	intact-crc:F3B8FAD19A239068	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000170345	uniprotkb:O95863	intact:EBI-6081475	intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842	psi-mi:fos_human_gene(display_short)|psi-mi:ENSG00000170345(display_long)	psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784528|imex:IM-21527-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N	-	-	-	figure legend:6F|comment:the promoter of FOS was only weakly enriched for Twist and Snail binding|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle)|taxid:9606(Homo sapiens)	-	2013/09/30	2014/10/16	-	rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606	intact-crc:9F5D65C64A63FE10	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q15672	ensembl:ENSG00000170345	intact:EBI-1797287|uniprotkb:Q92487|uniprotkb:Q99804|uniprotkb:A4D128|ensembl:ENSP00000242261	intact:EBI-6081475	psi-mi:twst1_human(display_long)|uniprotkb:H-twist(gene name synonym)|uniprotkb:TWIST1(gene name)|psi-mi:TWIST1(display_short)|uniprotkb:TWIST(gene name synonym)|uniprotkb:BHLHA38(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 38(gene name synonym)	psi-mi:fos_human_gene(display_short)|psi-mi:ENSG00000170345(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784521|imex:IM-21527-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_000465.1|refseq:XP_011513798.1|dip:DIP-45974N|ensembl:ENSG00000122691(gene)|ensembl:ENST00000242261(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001843"(neural tube closure)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003183"(mitral valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003253"(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032502"(developmental process)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:0060900"(embryonic camera-type eye formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070888"(E-box binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000276"(negative regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000780"(negative regulation of double-strand break repair)|go:"GO:2000793"(cell proliferation involved in heart valve development)|go:"GO:2000802"(positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638|rcsb pdb:2MJV|reactome:R-HSA-6785807|reactome:R-HSA-8878166|reactome:R-HSA-8939902	-	-	-	-	figure legend:6F|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle)|taxid:9606(Homo sapiens)	-	2013/09/30	2014/10/16	rogid:1+WEEh0ruAAKCxlJQCVzBqTrhIM9606	-	intact-crc:58B97C81A4B6F438	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000175592	uniprotkb:Q15672	intact:EBI-8784507	intact:EBI-1797287|uniprotkb:Q92487|uniprotkb:Q99804|uniprotkb:A4D128|ensembl:ENSP00000242261	psi-mi:fosl1_human_gene(display_short)|psi-mi:ENSG00000175592(display_long)	psi-mi:twst1_human(display_long)|uniprotkb:H-twist(gene name synonym)|uniprotkb:TWIST1(gene name)|psi-mi:TWIST1(display_short)|uniprotkb:TWIST(gene name synonym)|uniprotkb:BHLHA38(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 38(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784505|imex:IM-21527-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000465.1|refseq:XP_011513798.1|dip:DIP-45974N|ensembl:ENSG00000122691(gene)|ensembl:ENST00000242261(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001843"(neural tube closure)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003183"(mitral valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003253"(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032502"(developmental process)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:0060900"(embryonic camera-type eye formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070888"(E-box binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000276"(negative regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000780"(negative regulation of double-strand break repair)|go:"GO:2000793"(cell proliferation involved in heart valve development)|go:"GO:2000802"(positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR015789(Twist)|interpro:IPR036638|rcsb pdb:2MJV|reactome:R-HSA-6785807|reactome:R-HSA-8878166|reactome:R-HSA-8939902	-	-	-	figure legend:6F|causality statement:Q15672 increases expression of ENSG00000175592|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle)|taxid:9606(Homo sapiens)	-	2013/09/30	2014/10/16	-	rogid:1+WEEh0ruAAKCxlJQCVzBqTrhIM9606	intact-crc:6E1D59D29978D7DC	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:O95863	ensembl:ENSG00000175592	intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842	intact:EBI-8784507	psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym)	psi-mi:fosl1_human_gene(display_short)|psi-mi:ENSG00000175592(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tam et al. (2013)	imex:IM-21527|pubmed:24029232	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784513|imex:IM-21527-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N	-	-	-	-	figure legend:6F|comment:the promoter of FOS was only weakly enriched for Twist and Snail binding|causality statement:O95863 increases expression of ENSG00000175592|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hmle)|taxid:9606(Homo sapiens)	-	2013/09/30	2014/10/16	rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606	-	intact-crc:2A0360663C4B4E49	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)