#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53805-2 uniprotkb:P53805-2 intact:EBI-1541912|ensembl:ENSP00000370524 intact:EBI-1541912|ensembl:ENSP00000370524 psi-mi:p53805-2(display_long)|uniprotkb:RCAN1(gene name)|psi-mi:RCAN1(display_short)|uniprotkb:ADAPT78(gene name synonym)|uniprotkb:CSP1(gene name synonym)|uniprotkb:DSC1(gene name synonym)|uniprotkb:DSCR1(gene name synonym)|uniprotkb:Adapt78(gene name synonym)|uniprotkb:Down syndrome critical region protein 1(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 1(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:CALP1-S(isoform synonym) psi-mi:p53805-2(display_long)|uniprotkb:RCAN1(gene name)|psi-mi:RCAN1(display_short)|uniprotkb:ADAPT78(gene name synonym)|uniprotkb:CSP1(gene name synonym)|uniprotkb:DSC1(gene name synonym)|uniprotkb:DSCR1(gene name synonym)|uniprotkb:Adapt78(gene name synonym)|uniprotkb:Down syndrome critical region protein 1(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 1(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:CALP1-S(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Song et al. (2013) pubmed:24021800|imex:IM-21658 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-8829615|imex:IM-21658-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1541887(isoform-parent)|uniprotkb:P53805-2(isoform-parent)|ensembl:ENSG00000159200(gene)|ensembl:ENST00000381132(transcript) intact:EBI-1541887(isoform-parent)|uniprotkb:P53805-2(isoform-parent)|ensembl:ENSG00000159200(gene)|ensembl:ENST00000381132(transcript) - - - figure legend:1A|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/25 2014/10/16 rogid:OZrbrTBOMsbOsUCbRE1Nh6md0j09606 rogid:OZrbrTBOMsbOsUCbRE1Nh6md0j09606 intact-crc:473D4E7E9998471C|rigid:S8iPfwl42M8f1OLeCI387K12in4 false myc tag:?-?|O-phospho-L-threonine:192-192 flag tag:?-?|O-phospho-L-threonine:192-192 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P53805-2 uniprotkb:P53805-2 intact:EBI-1541912|ensembl:ENSP00000370524 intact:EBI-1541912|ensembl:ENSP00000370524 psi-mi:p53805-2(display_long)|uniprotkb:RCAN1(gene name)|psi-mi:RCAN1(display_short)|uniprotkb:ADAPT78(gene name synonym)|uniprotkb:CSP1(gene name synonym)|uniprotkb:DSC1(gene name synonym)|uniprotkb:DSCR1(gene name synonym)|uniprotkb:Adapt78(gene name synonym)|uniprotkb:Down syndrome critical region protein 1(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 1(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:CALP1-S(isoform synonym) psi-mi:p53805-2(display_long)|uniprotkb:RCAN1(gene name)|psi-mi:RCAN1(display_short)|uniprotkb:ADAPT78(gene name synonym)|uniprotkb:CSP1(gene name synonym)|uniprotkb:DSC1(gene name synonym)|uniprotkb:DSCR1(gene name synonym)|uniprotkb:Adapt78(gene name synonym)|uniprotkb:Down syndrome critical region protein 1(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 1(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:CALP1-S(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Song et al. (2013) pubmed:24021800|imex:IM-21658 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-8829672|imex:IM-21658-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1541887(isoform-parent)|uniprotkb:P53805-2(isoform-parent)|ensembl:ENSG00000159200(gene)|ensembl:ENST00000381132(transcript) intact:EBI-1541887(isoform-parent)|uniprotkb:P53805-2(isoform-parent)|ensembl:ENSG00000159200(gene)|ensembl:ENST00000381132(transcript) - - - figure legend:1B|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/10/25 2014/10/16 rogid:OZrbrTBOMsbOsUCbRE1Nh6md0j09606 rogid:OZrbrTBOMsbOsUCbRE1Nh6md0j09606 intact-crc:58155B95A822DC6E|rigid:S8iPfwl42M8f1OLeCI387K12in4 false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P53805-2 uniprotkb:P53805-2 intact:EBI-1541912|ensembl:ENSP00000370524 intact:EBI-1541912|ensembl:ENSP00000370524 psi-mi:p53805-2(display_long)|uniprotkb:RCAN1(gene name)|psi-mi:RCAN1(display_short)|uniprotkb:ADAPT78(gene name synonym)|uniprotkb:CSP1(gene name synonym)|uniprotkb:DSC1(gene name synonym)|uniprotkb:DSCR1(gene name synonym)|uniprotkb:Adapt78(gene name synonym)|uniprotkb:Down syndrome critical region protein 1(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 1(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:CALP1-S(isoform synonym) psi-mi:p53805-2(display_long)|uniprotkb:RCAN1(gene name)|psi-mi:RCAN1(display_short)|uniprotkb:ADAPT78(gene name synonym)|uniprotkb:CSP1(gene name synonym)|uniprotkb:DSC1(gene name synonym)|uniprotkb:DSCR1(gene name synonym)|uniprotkb:Adapt78(gene name synonym)|uniprotkb:Down syndrome critical region protein 1(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 1(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:CALP1-S(isoform synonym) psi-mi:"MI:0096"(pull down) Song et al. (2013) pubmed:24021800|imex:IM-21658 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-8829695|imex:IM-21658-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1541887(isoform-parent)|uniprotkb:P53805-2(isoform-parent)|ensembl:ENSG00000159200(gene)|ensembl:ENST00000381132(transcript) intact:EBI-1541887(isoform-parent)|uniprotkb:P53805-2(isoform-parent)|ensembl:ENSG00000159200(gene)|ensembl:ENST00000381132(transcript) - - - figure legend:1C|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/25 2014/10/16 rogid:OZrbrTBOMsbOsUCbRE1Nh6md0j09606 rogid:OZrbrTBOMsbOsUCbRE1Nh6md0j09606 intact-crc:AAB5EDC2C6C78691|rigid:S8iPfwl42M8f1OLeCI387K12in4 false myc tag:?-? mutation decreasing interaction:192-192|glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P53805-2 uniprotkb:P53805-2 intact:EBI-1541912|ensembl:ENSP00000370524 intact:EBI-1541912|ensembl:ENSP00000370524 psi-mi:p53805-2(display_long)|uniprotkb:RCAN1(gene name)|psi-mi:RCAN1(display_short)|uniprotkb:ADAPT78(gene name synonym)|uniprotkb:CSP1(gene name synonym)|uniprotkb:DSC1(gene name synonym)|uniprotkb:DSCR1(gene name synonym)|uniprotkb:Adapt78(gene name synonym)|uniprotkb:Down syndrome critical region protein 1(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 1(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:CALP1-S(isoform synonym) psi-mi:p53805-2(display_long)|uniprotkb:RCAN1(gene name)|psi-mi:RCAN1(display_short)|uniprotkb:ADAPT78(gene name synonym)|uniprotkb:CSP1(gene name synonym)|uniprotkb:DSC1(gene name synonym)|uniprotkb:DSCR1(gene name synonym)|uniprotkb:Adapt78(gene name synonym)|uniprotkb:Down syndrome critical region protein 1(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 1(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:CALP1-S(isoform synonym) psi-mi:"MI:0982"(electrophoretic mobility-based method) Song et al. (2013) pubmed:24021800|imex:IM-21658 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-8829754|imex:IM-21658-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1541887(isoform-parent)|uniprotkb:P53805-2(isoform-parent)|ensembl:ENSG00000159200(gene)|ensembl:ENST00000381132(transcript) intact:EBI-1541887(isoform-parent)|uniprotkb:P53805-2(isoform-parent)|ensembl:ENSG00000159200(gene)|ensembl:ENST00000381132(transcript) - - - figure legend:Fig 2|agonist:Recombinant mouse Dyrk1A|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/25 2014/10/16 rogid:OZrbrTBOMsbOsUCbRE1Nh6md0j09606 rogid:OZrbrTBOMsbOsUCbRE1Nh6md0j09606 intact-crc:CD75309D3182D58D|rigid:S8iPfwl42M8f1OLeCI387K12in4 false his tag:c-c|s tag:n-n his tag:c-c|s tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53805-2 uniprotkb:P53805-2 intact:EBI-1541912|ensembl:ENSP00000370524 intact:EBI-1541912|ensembl:ENSP00000370524 psi-mi:p53805-2(display_long)|uniprotkb:RCAN1(gene name)|psi-mi:RCAN1(display_short)|uniprotkb:ADAPT78(gene name synonym)|uniprotkb:CSP1(gene name synonym)|uniprotkb:DSC1(gene name synonym)|uniprotkb:DSCR1(gene name synonym)|uniprotkb:Adapt78(gene name synonym)|uniprotkb:Down syndrome critical region protein 1(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 1(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:CALP1-S(isoform synonym) psi-mi:p53805-2(display_long)|uniprotkb:RCAN1(gene name)|psi-mi:RCAN1(display_short)|uniprotkb:ADAPT78(gene name synonym)|uniprotkb:CSP1(gene name synonym)|uniprotkb:DSC1(gene name synonym)|uniprotkb:DSCR1(gene name synonym)|uniprotkb:Adapt78(gene name synonym)|uniprotkb:Down syndrome critical region protein 1(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 1(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:CALP1-S(isoform synonym) psi-mi:"MI:0982"(electrophoretic mobility-based method) Song et al. (2013) pubmed:24021800|imex:IM-21658 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-8829812|imex:IM-21658-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1541887(isoform-parent)|uniprotkb:P53805-2(isoform-parent)|ensembl:ENSG00000159200(gene)|ensembl:ENST00000381132(transcript) intact:EBI-1541887(isoform-parent)|uniprotkb:P53805-2(isoform-parent)|ensembl:ENSG00000159200(gene)|ensembl:ENST00000381132(transcript) - - - figure legend:Fig 2|agonist:Recombinant mouse Dyrk1A|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/25 2014/10/16 rogid:OZrbrTBOMsbOsUCbRE1Nh6md0j09606 rogid:OZrbrTBOMsbOsUCbRE1Nh6md0j09606 intact-crc:8283ED2A036ACF1A|rigid:fqh1frw4kbcIbt8KkZ4DwRs/7Q4 false his tag:c-c|s tag:n-n his tag:c-c|s tag:n-n 4 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53805-2 uniprotkb:P53805-2 intact:EBI-1541912|ensembl:ENSP00000370524 intact:EBI-1541912|ensembl:ENSP00000370524 psi-mi:p53805-2(display_long)|uniprotkb:RCAN1(gene name)|psi-mi:RCAN1(display_short)|uniprotkb:ADAPT78(gene name synonym)|uniprotkb:CSP1(gene name synonym)|uniprotkb:DSC1(gene name synonym)|uniprotkb:DSCR1(gene name synonym)|uniprotkb:Adapt78(gene name synonym)|uniprotkb:Down syndrome critical region protein 1(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 1(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:CALP1-S(isoform synonym) psi-mi:p53805-2(display_long)|uniprotkb:RCAN1(gene name)|psi-mi:RCAN1(display_short)|uniprotkb:ADAPT78(gene name synonym)|uniprotkb:CSP1(gene name synonym)|uniprotkb:DSC1(gene name synonym)|uniprotkb:DSCR1(gene name synonym)|uniprotkb:Adapt78(gene name synonym)|uniprotkb:Down syndrome critical region protein 1(gene name synonym)|uniprotkb:Myocyte-enriched calcineurin-interacting protein 1(gene name synonym)|uniprotkb:Regulator of calcineurin 1(gene name synonym)|uniprotkb:CALP1-S(isoform synonym) psi-mi:"MI:0982"(electrophoretic mobility-based method) Song et al. (2013) pubmed:24021800|imex:IM-21658 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-8829735|imex:IM-21658-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1541887(isoform-parent)|uniprotkb:P53805-2(isoform-parent)|ensembl:ENSG00000159200(gene)|ensembl:ENST00000381132(transcript) intact:EBI-1541887(isoform-parent)|uniprotkb:P53805-2(isoform-parent)|ensembl:ENSG00000159200(gene)|ensembl:ENST00000381132(transcript) - - - figure legend:Fig 2|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/25 2014/10/16 rogid:OZrbrTBOMsbOsUCbRE1Nh6md0j09606 rogid:OZrbrTBOMsbOsUCbRE1Nh6md0j09606 intact-crc:7FEA6E47978296CA|rigid:fqh1frw4kbcIbt8KkZ4DwRs/7Q4 false s tag:n-n|his tag:c-c s tag:n-n|his tag:c-c 2 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)