#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q0D2N8 uniprotkb:Q9UBK9 intact:EBI-8716526 intact:EBI-357355|ensembl:ENSP00000327797|uniprotkb:B2R561|uniprotkb:Q5JZG3|uniprotkb:Q9Y6E5|uniprotkb:A0A0C4DFR8 psi-mi:q0d2n8_human(display_long)|uniprotkb:SARM1(gene name)|psi-mi:SARM1(display_short)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym) psi-mi:uxt_human(display_long)|uniprotkb:UXT(gene name)|psi-mi:UXT(display_short)|uniprotkb:HSPC024(orf name)|uniprotkb:Ubiquitously expressed transcript protein(gene name synonym)|uniprotkb:Androgen receptor trapped clone 27 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Sethurathinam et al. (2013) pubmed:24021647|imex:IM-21412 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8716524|imex:IM-21412-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039184|interpro:IPR035897|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR000157(Toll-Interleukin receptor)|refseq:NP_055892.2|go:"GO:0007165"(signal transduction)|go:"GO:0030424"(axon)|go:"GO:0034128"(negative regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0048678"(response to axon injury)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating) ensembl:ENSG00000126756(gene)|ensembl:ENST00000333119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000785"(chromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048487"(beta-tubulin binding)|interpro:IPR003994(Prefoldin related, ubiquitously expressed transcript)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|mint:Q9UBK9|reactome:R-HSA-8953750|go:"GO:0003714"(transcription corepressor activity)|refseq:NP_004173.1|refseq:NP_705582.1 - - - figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/08/29 2014/10/16 rogid:/HSoys1wwOwOtTVWLw2QyD8HaQI9606 rogid:XhE14Q7CfwVXxJ4fTiRQTm3Idvk9606 intact-crc:E5EC1407D30EC4BE|rigid:AUJ4ynYs/P6Wa2OmUM2iOYJzSVI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UBK9 uniprotkb:Q0D2N8 intact:EBI-357355|ensembl:ENSP00000327797|uniprotkb:B2R561|uniprotkb:Q5JZG3|uniprotkb:Q9Y6E5|uniprotkb:A0A0C4DFR8 intact:EBI-8716526 psi-mi:uxt_human(display_long)|uniprotkb:UXT(gene name)|psi-mi:UXT(display_short)|uniprotkb:HSPC024(orf name)|uniprotkb:Ubiquitously expressed transcript protein(gene name synonym)|uniprotkb:Androgen receptor trapped clone 27 protein(gene name synonym) psi-mi:q0d2n8_human(display_long)|uniprotkb:SARM1(gene name)|psi-mi:SARM1(display_short)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sethurathinam et al. (2013) pubmed:24021647|imex:IM-21412 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8716585|imex:IM-21412-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126756(gene)|ensembl:ENST00000333119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000785"(chromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048487"(beta-tubulin binding)|interpro:IPR003994(Prefoldin related, ubiquitously expressed transcript)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|mint:Q9UBK9|reactome:R-HSA-8953750|go:"GO:0003714"(transcription corepressor activity)|refseq:NP_004173.1|refseq:NP_705582.1 interpro:IPR039184|interpro:IPR035897|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR000157(Toll-Interleukin receptor)|refseq:NP_055892.2|go:"GO:0007165"(signal transduction)|go:"GO:0030424"(axon)|go:"GO:0034128"(negative regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0048678"(response to axon injury)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating) - - - figure legend:f1b|comment:"We expressed SARM, UXT V1 or UXT V2 in HEK 293T cells to further assess their interactions by coimmunoprecipitation. Consistently, SARM was detected in both the UXT -V1 and -V2 10 immunoprecipitates and conversely, UXT -V1 and -V2 were detected in SARM immunoprecipitates (Fig. 1B), supporting that SARM interacts with both UXT isoforms."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/29 2014/10/16 rogid:XhE14Q7CfwVXxJ4fTiRQTm3Idvk9606 rogid:/HSoys1wwOwOtTVWLw2QyD8HaQI9606 intact-crc:81ED9E8527F8CA4F|rigid:AUJ4ynYs/P6Wa2OmUM2iOYJzSVI false flag tag:?-? v5 tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)