#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P16892	uniprotkb:P32917	intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783588|imex:IM-21742-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	crc64:5117980D20A1E7E2	crc64:0435BDA0196B2D6F	figure legend:Fig. 2a, Fig. 3a, Suppl. Fig. S2a, Suppl. Fig. S2b, Suppl. Fig. S4d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:B611C444A855FE00|rigid:88GnNWUrnKNfFdRBO5DHVjBdy0A	false	-	sufficient binding region:?-?(IPR021106)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P16892	uniprotkb:P06784	intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783588|imex:IM-21742-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	crc64:5117980D20A1E7E2	crc64:C8A75899CFBE8BDE	figure legend:Fig. 2a, Fig. 3a, Suppl. Fig. S2a, Suppl. Fig. S2b, Suppl. Fig. S4d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:B611C444A855FE00|rigid:88GnNWUrnKNfFdRBO5DHVjBdy0A	false	-	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P16892	uniprotkb:Q74ZU4	intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W	intact:EBI-8783698|ensemblfungi:AAS54594	psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name)	psi-mi:q74zu4_ashgo(display_long)|uniprotkb:AGOS_AGR104W(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783696|imex:IM-21742-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635	interpro:IPR038382|interpro:IPR021106|refseq:NP_986770.1|ensemblfungi:AGOS_AGR104W(gene)|ensemblfungi:AAS54594(transcript)	-	crc64:5117980D20A1E7E2	-	figure legend:Fig. 2a, Suppl. Fig. S2a, Suppl. Fig. S2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292	rogid:UkiXRKuTWIcgovaT8Wd0L7gu59E284811	intact-crc:C6B4272008393410|rigid:st0rqrkckNfZuRkmtbgcH9zLWzY	false	-	sufficient binding region:?-?(IPR021106)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P16892	uniprotkb:P06784	intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783696|imex:IM-21742-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	crc64:5117980D20A1E7E2	crc64:C8A75899CFBE8BDE	figure legend:Fig. 2a, Suppl. Fig. S2a, Suppl. Fig. S2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:C6B4272008393410|rigid:st0rqrkckNfZuRkmtbgcH9zLWzY	false	-	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A7TJH8	uniprotkb:P16892	intact:EBI-8783719|ensemblfungi:EDO17628	intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W	psi-mi:a7tjh8_vanpo(display_long)|uniprotkb:Kpol_1061p54(orf name)	psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:436907(vanpo)|taxid:436907("Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783727|imex:IM-21742-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR038382|interpro:IPR021106|interpro:IPR001841(Zinc finger, RING-type)|refseq:XP_001645486.1|ensemblfungi:EDO17628(transcript)|ensemblfungi:Kpol_1061p54(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)	refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635	-	-	crc64:5117980D20A1E7E2	figure legend:Fig. 2a, Suppl. Fig. S2a, Suppl. Fig. S2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:AuJqk1cXYGgNA9jHe00wwA+L+1c436907	rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292	intact-crc:EA8F087809D2E70A|rigid:/fDgJhWkORifiVPwFxsZ42EbBao	false	sufficient binding region:?-?(IPR021106)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A7TJH8	uniprotkb:P06784	intact:EBI-8783719|ensemblfungi:EDO17628	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:a7tjh8_vanpo(display_long)|uniprotkb:Kpol_1061p54(orf name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:436907(vanpo)|taxid:436907("Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783727|imex:IM-21742-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR038382|interpro:IPR021106|interpro:IPR001841(Zinc finger, RING-type)|refseq:XP_001645486.1|ensemblfungi:EDO17628(transcript)|ensemblfungi:Kpol_1061p54(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	-	crc64:C8A75899CFBE8BDE	figure legend:Fig. 2a, Suppl. Fig. S2a, Suppl. Fig. S2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:AuJqk1cXYGgNA9jHe00wwA+L+1c436907	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:EA8F087809D2E70A|rigid:/fDgJhWkORifiVPwFxsZ42EbBao	false	sufficient binding region:?-?(IPR021106)	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P16892	uniprotkb:Q6FL43	intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W	intact:EBI-8783743|ensemblfungi:CAG62021	psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name)	psi-mi:q6fl43_canga(display_long)|uniprotkb:CAGL0L06336g(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:284593(canga)|taxid:284593("Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783751|imex:IM-21742-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635	interpro:IPR038382|interpro:IPR021106|interpro:IPR001841(Zinc finger, RING-type)|refseq:XP_449051.1|ensemblfungi:CAG62021(transcript)|ensemblfungi:CAGL0L06336g(gene)	-	crc64:5117980D20A1E7E2	-	figure legend:Fig. 2a, Suppl. Fig. S2a, Suppl. Fig. S2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292	rogid:mjMxq1ADu3hSOncCvE+adeWs+lI284593	intact-crc:4FDD29981114B83D|rigid:uB1v7sjrN0rInYlRHbzElGDh9fE	false	-	sufficient binding region:?-?(IPR021106)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P16892	uniprotkb:P06784	intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783751|imex:IM-21742-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	crc64:5117980D20A1E7E2	crc64:C8A75899CFBE8BDE	figure legend:Fig. 2a, Suppl. Fig. S2a, Suppl. Fig. S2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:4FDD29981114B83D|rigid:uB1v7sjrN0rInYlRHbzElGDh9fE	false	-	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:C5DSP8	uniprotkb:P16892	intact:EBI-8783770|ensemblfungi:CAR26809	intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W	psi-mi:c5dsp8_zygrc(display_long)|uniprotkb:ZYRO0C02002g(locus name)	psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559307(zygrc)|taxid:559307("Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783768|imex:IM-21742-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038382|interpro:IPR021106|refseq:XP_002495742.1|ensemblfungi:CAR26809(transcript)|ensemblfungi:ZYRO0C02002g(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0010525"(regulation of transposition, RNA-mediated)	refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635	-	-	crc64:5117980D20A1E7E2	figure legend:Fig. 2a, Suppl. Fig. S2a, Suppl. Fig. S2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:8JpBMVFe+IW5AjrWUhWm7tR0aQw559307	rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292	intact-crc:A650D49809D7D282|rigid:yXqjVD4sOTDMCrpiS6wY4Wzf+mw	false	sufficient binding region:?-?(IPR021106)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:C5DSP8	uniprotkb:P06784	intact:EBI-8783770|ensemblfungi:CAR26809	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:c5dsp8_zygrc(display_long)|uniprotkb:ZYRO0C02002g(locus name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559307(zygrc)|taxid:559307("Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783768|imex:IM-21742-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR038382|interpro:IPR021106|refseq:XP_002495742.1|ensemblfungi:CAR26809(transcript)|ensemblfungi:ZYRO0C02002g(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0010525"(regulation of transposition, RNA-mediated)	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	-	crc64:C8A75899CFBE8BDE	figure legend:Fig. 2a, Suppl. Fig. S2a, Suppl. Fig. S2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:8JpBMVFe+IW5AjrWUhWm7tR0aQw559307	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:A650D49809D7D282|rigid:yXqjVD4sOTDMCrpiS6wY4Wzf+mw	false	sufficient binding region:?-?(IPR021106)	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P16892	uniprotkb:P32917	intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783790|imex:IM-21742-9	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	crc64:5117980D20A1E7E2	crc64:0435BDA0196B2D6F	figure legend:Fig. 2b, Fig. 3b, Suppl. Fig. S3a, Suppl. Fig. S3b, Suppl. Fig. S3d, Suppl. Fig. S5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:C55ABFE02EF9248A|rigid:z8bRRQgHqqK7UzwqDKBKeV8YYTo	false	-	sufficient binding region:?-?(IPR021651)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A7TJH8	uniprotkb:P16892	intact:EBI-8783719|ensemblfungi:EDO17628	intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W	psi-mi:a7tjh8_vanpo(display_long)|uniprotkb:Kpol_1061p54(orf name)	psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:436907(vanpo)|taxid:436907("Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783797|imex:IM-21742-10	-	-	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR038382|interpro:IPR021106|interpro:IPR001841(Zinc finger, RING-type)|refseq:XP_001645486.1|ensemblfungi:EDO17628(transcript)|ensemblfungi:Kpol_1061p54(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)	refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635	-	-	crc64:5117980D20A1E7E2	figure legend:Fig. 2b, Fig. 5b, Suppl. Fig. S3a, Suppl. Fig. S3b, Suppl. Fig. S3d, Suppl. Fig. S5a, Suppl. Fig. S5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:AuJqk1cXYGgNA9jHe00wwA+L+1c436907	rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292	intact-crc:15ADC5A1A96EA866|rigid:nvY7uiLymQnw6AjFm+KJcq8Bxyw	false	necessary binding region:254-293|mutation disrupting interaction:255-255,262-262,254-254,265-265,267-267	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P16892	uniprotkb:P16892	intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W	intact:EBI-7193|uniprotkb:D6VPY4|ensemblfungi:YBL016W	psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name)	psi-mi:fus3_yeast(display_long)|uniprotkb:FUS3(gene name)|psi-mi:FUS3(display_short)|uniprotkb:DAC2(gene name synonym)|uniprotkb:YBL016W(locus name)|uniprotkb:YBL0303(orf name)|uniprotkb:YBL03.21(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783803|imex:IM-21742-11	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635	refseq:NP_009537.1|sgd:S000000112|dip:DIP-714N|mint:P16892|ensemblfungi:YBL016W(gene)|ensemblfungi:YBL016W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2B9F|rcsb pdb:2B9H|rcsb pdb:2B9I|rcsb pdb:2B9J|rcsb pdb:2F49|rcsb pdb:2F9G|rcsb pdb:2FA2|reactome:R-SCE-110056|reactome:R-SCE-111995|reactome:R-SCE-112409|reactome:R-SCE-112411|reactome:R-SCE-170968|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-3371453|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-445144|reactome:R-SCE-450341|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635	-	crc64:5117980D20A1E7E2	crc64:5117980D20A1E7E2	figure legend:Fig. 2b, Fig. 3b, Suppl. Fig. S3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292	rogid:FaPNQ+7PYnYCFIVspwEcRFOgv0w559292	intact-crc:FBA7C18CB67818FD|rigid:bIQydQs1x5b31sCAKyUXJhWnpVI	false	-	-	-	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6FPF2	uniprotkb:P32917	intact:EBI-8783845|ensemblfungi:CAG60841	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:q6fpf2_canga(display_long)|uniprotkb:CAGL0J04290g(locus name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:284593(canga)|taxid:284593("Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783843|imex:IM-21742-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_447892.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAG60841(transcript)|ensemblfungi:CAGL0J04290g(gene)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	-	crc64:0435BDA0196B2D6F	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:MgwbdStP1NPwfaEcEGb8dZ1LTwg284593	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:4014FB0D51B1446E|rigid:H4UMwctCRRN7q8bOpAljGjd6CtQ	false	-	sufficient binding region:?-?(IPR021106)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6FPF2	uniprotkb:P06784	intact:EBI-8783845|ensemblfungi:CAG60841	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:q6fpf2_canga(display_long)|uniprotkb:CAGL0J04290g(locus name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:284593(canga)|taxid:284593("Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783843|imex:IM-21742-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_447892.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAG60841(transcript)|ensemblfungi:CAGL0J04290g(gene)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	-	crc64:C8A75899CFBE8BDE	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:MgwbdStP1NPwfaEcEGb8dZ1LTwg284593	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:4014FB0D51B1446E|rigid:H4UMwctCRRN7q8bOpAljGjd6CtQ	false	-	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P14681	uniprotkb:P06784	intact:EBI-9945|uniprotkb:Q45U43|uniprotkb:D6VUH8|ensemblfungi:YGR040W	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:kss1_yeast(display_long)|uniprotkb:KSS1(gene name)|psi-mi:KSS1(display_short)|uniprotkb:Kinase suppressor of SST2(gene name synonym)|uniprotkb:YGR040W(locus name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783924|imex:IM-21742-13	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003272|ensemblfungi:YGR040W(gene)|ensemblfungi:YGR040W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-111995|reactome:R-SCE-112411|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635|refseq:NP_011554.3|reactome:R-SCE-112409|reactome:R-SCE-3371453|reactome:R-SCE-445144|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|dip:DIP-60N|reactome:R-SCE-170968|reactome:R-SCE-450341	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	crc64:5FA42161B5FD51B5	crc64:C8A75899CFBE8BDE	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:xE1y1jku+iWy4xzv9wUCul1AFZs559292	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:73FDAD2CE41D5322|rigid:v9VALaELwEARboEE7iHaBr1KUi0	false	-	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06784	uniprotkb:Q6CY79	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	intact:EBI-8783943|ensemblfungi:CAH02698	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:q6cy79_klula(display_long)|uniprotkb:KLLA0_A02497g(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783941|imex:IM-21742-14	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	refseq:XP_451110.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAH02698(transcript)|ensemblfungi:KLLA0_A02497g(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	crc64:C8A75899CFBE8BDE	-	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	rogid:Ej7hiRjyWG2cjWYiPKx7NtCt7QY284590	intact-crc:DA6342BC454110CA|rigid:MvPGVbj8vFHTzDLkhHvyYDWfTSA	false	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q75CV7	uniprotkb:P06784	intact:EBI-8784025|ensemblfungi:AAS51037	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:q75cv7_ashgo(display_long)|uniprotkb:AGOS_ACL191C(orf name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784040|imex:IM-21742-15	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_983213.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:AAS51037(transcript)|ensemblfungi:AGOS_ACL191C(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	-	crc64:C8A75899CFBE8BDE	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:apT50mckGM1JA/bJYDLiiAo5Xck284811	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:49BBF9CE5E030762|rigid:Xcno0sigImFgtrwZDefAPFp3ZyQ	false	-	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P14681	uniprotkb:P14681	intact:EBI-9945|uniprotkb:Q45U43|uniprotkb:D6VUH8|ensemblfungi:YGR040W	intact:EBI-9945|uniprotkb:Q45U43|uniprotkb:D6VUH8|ensemblfungi:YGR040W	psi-mi:kss1_yeast(display_long)|uniprotkb:KSS1(gene name)|psi-mi:KSS1(display_short)|uniprotkb:Kinase suppressor of SST2(gene name synonym)|uniprotkb:YGR040W(locus name)	psi-mi:kss1_yeast(display_long)|uniprotkb:KSS1(gene name)|psi-mi:KSS1(display_short)|uniprotkb:Kinase suppressor of SST2(gene name synonym)|uniprotkb:YGR040W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784061|imex:IM-21742-16	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003272|ensemblfungi:YGR040W(gene)|ensemblfungi:YGR040W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-111995|reactome:R-SCE-112411|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635|refseq:NP_011554.3|reactome:R-SCE-112409|reactome:R-SCE-3371453|reactome:R-SCE-445144|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|dip:DIP-60N|reactome:R-SCE-170968|reactome:R-SCE-450341	sgd:S000003272|ensemblfungi:YGR040W(gene)|ensemblfungi:YGR040W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-111995|reactome:R-SCE-112411|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635|refseq:NP_011554.3|reactome:R-SCE-112409|reactome:R-SCE-3371453|reactome:R-SCE-445144|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|dip:DIP-60N|reactome:R-SCE-170968|reactome:R-SCE-450341	-	crc64:5FA42161B5FD51B5	crc64:5FA42161B5FD51B5	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:xE1y1jku+iWy4xzv9wUCul1AFZs559292	rogid:xE1y1jku+iWy4xzv9wUCul1AFZs559292	intact-crc:00EFF6869FF4BBA7|rigid:UExNI/pQjwfxf76g4hKDev+WY1E	false	-	-	-	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6CY79	uniprotkb:Q6CY79	intact:EBI-8783943|ensemblfungi:CAH02698	intact:EBI-8783943|ensemblfungi:CAH02698	psi-mi:q6cy79_klula(display_long)|uniprotkb:KLLA0_A02497g(orf name)	psi-mi:q6cy79_klula(display_long)|uniprotkb:KLLA0_A02497g(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)")	taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784064|imex:IM-21742-17	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_451110.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAH02698(transcript)|ensemblfungi:KLLA0_A02497g(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:XP_451110.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAH02698(transcript)|ensemblfungi:KLLA0_A02497g(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	-	-	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:Ej7hiRjyWG2cjWYiPKx7NtCt7QY284590	rogid:Ej7hiRjyWG2cjWYiPKx7NtCt7QY284590	intact-crc:A97119163EA8F84F|rigid:3JIJWxbxmMenN4wyxmPFpPVJtGw	false	-	-	-	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q75CV7	uniprotkb:Q75CV7	intact:EBI-8784025|ensemblfungi:AAS51037	intact:EBI-8784025|ensemblfungi:AAS51037	psi-mi:q75cv7_ashgo(display_long)|uniprotkb:AGOS_ACL191C(orf name)	psi-mi:q75cv7_ashgo(display_long)|uniprotkb:AGOS_ACL191C(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)")	taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784067|imex:IM-21742-18	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_983213.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:AAS51037(transcript)|ensemblfungi:AGOS_ACL191C(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:NP_983213.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:AAS51037(transcript)|ensemblfungi:AGOS_ACL191C(gene)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	-	-	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:apT50mckGM1JA/bJYDLiiAo5Xck284811	rogid:apT50mckGM1JA/bJYDLiiAo5Xck284811	intact-crc:3AA9A26425EAEFE7|rigid:Zmis8zFRuQWkSPLNHx1ymDwEGY4	false	-	-	-	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5A1D3	uniprotkb:Q5A1D3	intact:EBI-8783371|uniprotkb:O13435|uniprotkb:P28869|uniprotkb:P87079|uniprotkb:P87080|uniprotkb:P87081|uniprotkb:P87082|uniprotkb:P87083|uniprotkb:P87084|uniprotkb:P87085|uniprotkb:P87086|uniprotkb:P87322|uniprotkb:Q6LC13|uniprotkb:A0A1D8PMK1	intact:EBI-8783371|uniprotkb:O13435|uniprotkb:P28869|uniprotkb:P87079|uniprotkb:P87080|uniprotkb:P87081|uniprotkb:P87082|uniprotkb:P87083|uniprotkb:P87084|uniprotkb:P87085|uniprotkb:P87086|uniprotkb:P87322|uniprotkb:Q6LC13|uniprotkb:A0A1D8PMK1	psi-mi:erk1_canal(display_long)|uniprotkb:CEK1(gene name)|psi-mi:CEK1(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:MAP kinase 1(gene name synonym)|uniprotkb:CaO19.10404(orf name)|uniprotkb:CaO19.2886(orf name)|uniprotkb:CAALFM_C406480CA(locus name)	psi-mi:erk1_canal(display_long)|uniprotkb:CEK1(gene name)|psi-mi:CEK1(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:MAP kinase 1(gene name synonym)|uniprotkb:CaO19.10404(orf name)|uniprotkb:CaO19.2886(orf name)|uniprotkb:CAALFM_C406480CA(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:237561(canal)|taxid:237561("Candida albicans (strain SC5314 / ATCC MYA-2876)")	taxid:237561(canal)|taxid:237561("Candida albicans (strain SC5314 / ATCC MYA-2876)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784070|imex:IM-21742-19	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_715542.2|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0030447"(filamentous growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0036170"(filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:0036180"(filamentous growth of a population of unicellular organisms in response to biotic stimulus)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:1900445"(positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus)|go:"GO:1990277"(parasexual conjugation with cellular fusion)	interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_715542.2|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0030447"(filamentous growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0036170"(filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:0036180"(filamentous growth of a population of unicellular organisms in response to biotic stimulus)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:1900445"(positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus)|go:"GO:1990277"(parasexual conjugation with cellular fusion)	-	-	-	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2017/03/30	rogid:gfbxkgS8l9FDVkxy4SHurMzw9iI237561	rogid:gfbxkgS8l9FDVkxy4SHurMzw9iI237561	intact-crc:3F738C895B6D25C9|rigid:J+TQkYnsVHBmxSvJrSC15mScy/g	false	-	-	-	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:C8V7D1	uniprotkb:C8V7D1	intact:EBI-8783425|ensemblfungi:CBF75537	intact:EBI-8783425|ensemblfungi:CBF75537	psi-mi:c8v7d1_emeni(display_long)|uniprotkb:mpkB(gene name)|psi-mi:mpkB(display_short)|uniprotkb:ANIA_03719(orf name)	psi-mi:c8v7d1_emeni(display_long)|uniprotkb:mpkB(gene name)|psi-mi:mpkB(display_short)|uniprotkb:ANIA_03719(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:227321(emeni)|taxid:227321(Emericella nidulans)	taxid:227321(emeni)|taxid:227321(Emericella nidulans)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784073|imex:IM-21742-20	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0010914"(positive regulation of sterigmatocystin biosynthetic process)|go:"GO:0030437"(ascospore formation)|go:"GO:0033246"(positive regulation of penicillin metabolic process)|go:"GO:0034293"(sexual sporulation)|go:"GO:0035146"(tube fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042318"(penicillin biosynthetic process)|go:"GO:0045461"(sterigmatocystin biosynthetic process)|go:"GO:0075296"(positive regulation of ascospore formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900376"(regulation of secondary metabolite biosynthetic process)|go:"GO:0005737"(cytoplasm)|ensemblfungi:ANIA_03719(gene)|ensemblfungi:CBF75537(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000909"(sporocarp development involved in sexual reproduction)|go:"GO:0001411"(hyphal tip)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)	interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0010914"(positive regulation of sterigmatocystin biosynthetic process)|go:"GO:0030437"(ascospore formation)|go:"GO:0033246"(positive regulation of penicillin metabolic process)|go:"GO:0034293"(sexual sporulation)|go:"GO:0035146"(tube fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042318"(penicillin biosynthetic process)|go:"GO:0045461"(sterigmatocystin biosynthetic process)|go:"GO:0075296"(positive regulation of ascospore formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900376"(regulation of secondary metabolite biosynthetic process)|go:"GO:0005737"(cytoplasm)|ensemblfungi:ANIA_03719(gene)|ensemblfungi:CBF75537(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000909"(sporocarp development involved in sexual reproduction)|go:"GO:0001411"(hyphal tip)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)	-	-	-	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:dUbXGpALcJWdYArIl4x+4GPRwa0227321	rogid:dUbXGpALcJWdYArIl4x+4GPRwa0227321	intact-crc:737A89960A8D7CE5|rigid:eix/Mdq2codWfmfGzdEBJmji/qw	false	-	-	-	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-8783462	intact:EBI-8783462	-	-	psi-mi:q1k6i1_neucr(display_short)|psi-mi:EBI-8783462(display_long)|uniprotkb:NCU02393(orf name)	psi-mi:q1k6i1_neucr(display_short)|psi-mi:EBI-8783462(display_long)|uniprotkb:NCU02393(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:367110(neucr)|taxid:367110("Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)")	taxid:367110(neucr)|taxid:367110("Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784076|imex:IM-21742-21	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q1K6I1(uniprot-removed-ac)	uniprotkb:Q1K6I1(uniprot-removed-ac)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:mKyMj5sK5mGpuI3iv2wlEBK2llw367110	rogid:mKyMj5sK5mGpuI3iv2wlEBK2llw367110	intact-crc:38390D5D340B212C|rigid:fpFK/V90fhY6rYrzHshmNztCtHw	false	-	-	-	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6BNP1	uniprotkb:Q6BNP1	intact:EBI-8784088|ensemblfungi:CAG88452	intact:EBI-8784088|ensemblfungi:CAG88452	psi-mi:q6bnp1_debha(display_long)|uniprotkb:DEHA2E20086g(locus name)	psi-mi:q6bnp1_debha(display_long)|uniprotkb:DEHA2E20086g(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:284592(debha)|taxid:284592("Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)")	taxid:284592(debha)|taxid:284592("Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784086|imex:IM-21742-22	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_460179.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAG88452(transcript)|ensemblfungi:DEHA2E20086g(gene)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:XP_460179.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAG88452(transcript)|ensemblfungi:DEHA2E20086g(gene)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	-	-	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:JEdqvO3CseI7DdPMydxFaPR1zFY284592	rogid:JEdqvO3CseI7DdPMydxFaPR1zFY284592	intact-crc:4322FFE75E6C35B2|rigid:FCa1zezDHPshI0Fyw3KVkDQzffI	false	-	-	-	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32917	uniprotkb:Q6FPF2	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	intact:EBI-8783845|ensemblfungi:CAG60841	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:q6fpf2_canga(display_long)|uniprotkb:CAGL0J04290g(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:284593(canga)|taxid:284593("Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8784103|imex:IM-21742-23	-	-	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	refseq:XP_447892.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAG60841(transcript)|ensemblfungi:CAGL0J04290g(gene)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	crc64:0435BDA0196B2D6F	-	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	rogid:MgwbdStP1NPwfaEcEGb8dZ1LTwg284593	intact-crc:C19371467DD46A0E|rigid:bioUPg4DhzsLjqW4tQNXaMm5awA	false	sufficient binding region:?-?(IPR021651)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:C5M3M0	uniprotkb:P32917	intact:EBI-8785223|ensemblfungi:EER35920	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:c5m3m0_cantt(display_long)|uniprotkb:CTRG_00659(orf name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:294747(cantt)|taxid:294747("Candida tropicalis (strain ATCC MYA-3404 / T1)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8785221|imex:IM-21742-24	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_002545878.1|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CTRG_00659(gene)|ensemblfungi:EER35920(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR011009(Protein kinase-like)	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	-	crc64:0435BDA0196B2D6F	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:oSwgGn0Wqy34kNXIJR5X0SF4M4k294747	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:DD94405C70B2D956|rigid:4qR5/YnubTB8UHdoNT/xKhIh58c	false	-	sufficient binding region:?-?(IPR021651)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32917	intact:EBI-8785242	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	-	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:q5a281_canal(display_short)|psi-mi:EBI-8785242(display_long)|uniprotkb:orf19.460(locus name)|uniprotkb:CEK2(gene name)|psi-mi:CEK2(display_short)|uniprotkb:CaO19.460(orf name)|uniprotkb:CaO19.8091(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:237561(canal)|taxid:237561("Candida albicans (strain SC5314 / ATCC MYA-2876)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8785282|imex:IM-21742-25	-	-	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	uniprotkb:Q5A281(uniprot-removed-ac)	-	crc64:0435BDA0196B2D6F	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	rogid:DAbDB5KRTtiVNJKec+UwqMpXEwo237561	intact-crc:6907640C72D8882B|rigid:gexL9GRgblO4qH85IB01MeUgtww	false	sufficient binding region:?-?(IPR021651)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A5E0P6	uniprotkb:P32917	intact:EBI-8785291|ensemblfungi:EDK45004	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:a5e0p6_lodel(display_long)|uniprotkb:LELG_03183(orf name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:379508(lodel)|taxid:379508("Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8785305|imex:IM-21742-26	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_001525255.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:EDK45004(transcript)|ensemblfungi:LELG_03183(gene)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	-	crc64:0435BDA0196B2D6F	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:D6igUnRhcb9HKgtiOBlRF09fKu0379508	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:CFE73FB976BBF455|rigid:/ap5nEqGUdOYnBlpv4bgwUKm9Uo	false	-	sufficient binding region:?-?(IPR021651)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32917	uniprotkb:P27638	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	intact:EBI-2104356|ensemblfungi:"SPAC31G5.09c.1:pep"	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:spk1_schpo(display_long)|uniprotkb:spk1(gene name)|psi-mi:spk1(display_short)|uniprotkb:SPAC31G5.09c(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8785312|imex:IM-21742-27	-	-	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	reactome:R-SPO-112409|reactome:R-SPO-198753|reactome:R-SPO-202670|reactome:R-SPO-3371453|reactome:R-SPO-5673001|reactome:R-SPO-110056|reactome:R-SPO-112411|reactome:R-SPO-445144|reactome:R-SPO-5674135|reactome:R-SPO-5674499|reactome:R-SPO-170968|refseq:NP_594009.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-2559582|reactome:R-SPO-375165|reactome:R-SPO-5668599|reactome:R-SPO-5675221|reactome:R-SPO-5687128|reactome:R-SPO-881907|reactome:R-SPO-6798695|reactome:R-SPO-450341|reactome:R-SPO-111995|reactome:R-SPO-437239|reactome:R-SPO-9634635|ensemblfungi:SPAC31G5.09c(gene)|ensemblfungi:SPAC31G5.09c.1(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	crc64:0435BDA0196B2D6F	-	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	rogid:qH6Zs+UeAarxVUH1p86FeFXkpcY284812	intact-crc:2D906BDBC1865E45|rigid:tGwvO8W8+xIpjq0uFpO62e0Hzk4	false	sufficient binding region:?-?(IPR021651)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32917	uniprotkb:Q6CNR3	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	intact:EBI-8785667|ensemblfungi:CAG99513	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:q6cnr3_klula(display_long)|uniprotkb:KLLA0_E10539g(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8785682|imex:IM-21742-28	-	-	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	refseq:XP_454426.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAG99513(transcript)|ensemblfungi:KLLA0_E10539g(gene)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	crc64:0435BDA0196B2D6F	-	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	rogid:JqGHfKFT29rZDTwAVuYh7fCtA1k284590	intact-crc:BCC2D751166CE138|rigid:0thhv2gQ0aKtXW35neqY1zpMFP8	false	sufficient binding region:?-?(IPR021651)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6CNR3	uniprotkb:P32917	intact:EBI-8785667|ensemblfungi:CAG99513	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:q6cnr3_klula(display_long)|uniprotkb:KLLA0_E10539g(orf name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8785700|imex:IM-21742-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_454426.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAG99513(transcript)|ensemblfungi:KLLA0_E10539g(gene)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	-	crc64:0435BDA0196B2D6F	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:JqGHfKFT29rZDTwAVuYh7fCtA1k284590	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:3D455D1A3A09CF58|rigid:uMKYTxMhTpnXv144lvSLbYXE+FQ	false	-	sufficient binding region:?-?(IPR021106)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6CNR3	uniprotkb:P06784	intact:EBI-8785667|ensemblfungi:CAG99513	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:q6cnr3_klula(display_long)|uniprotkb:KLLA0_E10539g(orf name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:284590(klula)|taxid:284590("Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8785700|imex:IM-21742-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_454426.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAG99513(transcript)|ensemblfungi:KLLA0_E10539g(gene)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	-	crc64:C8A75899CFBE8BDE	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:JqGHfKFT29rZDTwAVuYh7fCtA1k284590	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:3D455D1A3A09CF58|rigid:uMKYTxMhTpnXv144lvSLbYXE+FQ	false	-	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-8785242	uniprotkb:P32917	-	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:q5a281_canal(display_short)|psi-mi:EBI-8785242(display_long)|uniprotkb:orf19.460(locus name)|uniprotkb:CEK2(gene name)|psi-mi:CEK2(display_short)|uniprotkb:CaO19.460(orf name)|uniprotkb:CaO19.8091(orf name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:237561(canal)|taxid:237561("Candida albicans (strain SC5314 / ATCC MYA-2876)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8871753|imex:IM-21742-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q5A281(uniprot-removed-ac)	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	crc64:0435BDA0196B2D6F	figure legend:Fig. 3a, Suppl. Fig. S4e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:DAbDB5KRTtiVNJKec+UwqMpXEwo237561	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:36A91B8BD6CE8CD3|rigid:ZPyNp2UloeyBqKewXUc3T9JX3lg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-8785242	uniprotkb:P06784	-	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:q5a281_canal(display_short)|psi-mi:EBI-8785242(display_long)|uniprotkb:orf19.460(locus name)|uniprotkb:CEK2(gene name)|psi-mi:CEK2(display_short)|uniprotkb:CaO19.460(orf name)|uniprotkb:CaO19.8091(orf name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:237561(canal)|taxid:237561("Candida albicans (strain SC5314 / ATCC MYA-2876)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8871753|imex:IM-21742-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q5A281(uniprot-removed-ac)	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	crc64:C8A75899CFBE8BDE	figure legend:Fig. 3a, Suppl. Fig. S4e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:DAbDB5KRTtiVNJKec+UwqMpXEwo237561	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:36A91B8BD6CE8CD3|rigid:ZPyNp2UloeyBqKewXUc3T9JX3lg	false	-	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:C8V7D1	uniprotkb:P32917	intact:EBI-8783425|ensemblfungi:CBF75537	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:c8v7d1_emeni(display_long)|uniprotkb:mpkB(gene name)|psi-mi:mpkB(display_short)|uniprotkb:ANIA_03719(orf name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:227321(emeni)|taxid:227321(Emericella nidulans)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8871988|imex:IM-21742-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0010914"(positive regulation of sterigmatocystin biosynthetic process)|go:"GO:0030437"(ascospore formation)|go:"GO:0033246"(positive regulation of penicillin metabolic process)|go:"GO:0034293"(sexual sporulation)|go:"GO:0035146"(tube fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042318"(penicillin biosynthetic process)|go:"GO:0045461"(sterigmatocystin biosynthetic process)|go:"GO:0075296"(positive regulation of ascospore formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900376"(regulation of secondary metabolite biosynthetic process)|go:"GO:0005737"(cytoplasm)|ensemblfungi:ANIA_03719(gene)|ensemblfungi:CBF75537(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000909"(sporocarp development involved in sexual reproduction)|go:"GO:0001411"(hyphal tip)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	-	crc64:0435BDA0196B2D6F	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:dUbXGpALcJWdYArIl4x+4GPRwa0227321	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:B13A5147BC53A60B|rigid:Q7ro1Y2scRRpi6pDBHX9WDjYN/Y	false	-	sufficient binding region:?-?(IPR021106)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:C8V7D1	uniprotkb:P06784	intact:EBI-8783425|ensemblfungi:CBF75537	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:c8v7d1_emeni(display_long)|uniprotkb:mpkB(gene name)|psi-mi:mpkB(display_short)|uniprotkb:ANIA_03719(orf name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:227321(emeni)|taxid:227321(Emericella nidulans)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8871988|imex:IM-21742-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0010914"(positive regulation of sterigmatocystin biosynthetic process)|go:"GO:0030437"(ascospore formation)|go:"GO:0033246"(positive regulation of penicillin metabolic process)|go:"GO:0034293"(sexual sporulation)|go:"GO:0035146"(tube fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042318"(penicillin biosynthetic process)|go:"GO:0045461"(sterigmatocystin biosynthetic process)|go:"GO:0075296"(positive regulation of ascospore formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900376"(regulation of secondary metabolite biosynthetic process)|go:"GO:0005737"(cytoplasm)|ensemblfungi:ANIA_03719(gene)|ensemblfungi:CBF75537(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000909"(sporocarp development involved in sexual reproduction)|go:"GO:0001411"(hyphal tip)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	-	crc64:C8A75899CFBE8BDE	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:dUbXGpALcJWdYArIl4x+4GPRwa0227321	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:B13A5147BC53A60B|rigid:Q7ro1Y2scRRpi6pDBHX9WDjYN/Y	false	-	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6BNP1	uniprotkb:P32917	intact:EBI-8784088|ensemblfungi:CAG88452	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:q6bnp1_debha(display_long)|uniprotkb:DEHA2E20086g(locus name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:284592(debha)|taxid:284592("Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8872079|imex:IM-21742-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_460179.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAG88452(transcript)|ensemblfungi:DEHA2E20086g(gene)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	-	crc64:0435BDA0196B2D6F	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:JEdqvO3CseI7DdPMydxFaPR1zFY284592	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:53ACF10440854F01|rigid:Fd2ap2wFB/eAwBZvAW8bKiHEUvo	false	-	sufficient binding region:?-?(IPR021106)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6BNP1	uniprotkb:P06784	intact:EBI-8784088|ensemblfungi:CAG88452	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:q6bnp1_debha(display_long)|uniprotkb:DEHA2E20086g(locus name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:284592(debha)|taxid:284592("Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8872079|imex:IM-21742-33	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_460179.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CAG88452(transcript)|ensemblfungi:DEHA2E20086g(gene)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	-	crc64:C8A75899CFBE8BDE	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:JEdqvO3CseI7DdPMydxFaPR1zFY284592	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:53ACF10440854F01|rigid:Fd2ap2wFB/eAwBZvAW8bKiHEUvo	false	-	mutation:359-359,363-363|maltose binding protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-8783462	uniprotkb:P32917	-	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:q1k6i1_neucr(display_short)|psi-mi:EBI-8783462(display_long)|uniprotkb:NCU02393(orf name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:367110(neucr)|taxid:367110("Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8872028|imex:IM-21742-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q1K6I1(uniprot-removed-ac)	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	crc64:0435BDA0196B2D6F	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:mKyMj5sK5mGpuI3iv2wlEBK2llw367110	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:E7FF892854B1AA4D|rigid:YUdDB32XyA7f0EV3Ejd01/mVBa8	false	-	sufficient binding region:?-?(IPR021106)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-8783462	uniprotkb:P06784	-	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:q1k6i1_neucr(display_short)|psi-mi:EBI-8783462(display_long)|uniprotkb:NCU02393(orf name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:367110(neucr)|taxid:367110("Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8872028|imex:IM-21742-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q1K6I1(uniprot-removed-ac)	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	crc64:C8A75899CFBE8BDE	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:mKyMj5sK5mGpuI3iv2wlEBK2llw367110	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:E7FF892854B1AA4D|rigid:YUdDB32XyA7f0EV3Ejd01/mVBa8	false	-	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5A1D3	uniprotkb:P32917	intact:EBI-8783371|uniprotkb:O13435|uniprotkb:P28869|uniprotkb:P87079|uniprotkb:P87080|uniprotkb:P87081|uniprotkb:P87082|uniprotkb:P87083|uniprotkb:P87084|uniprotkb:P87085|uniprotkb:P87086|uniprotkb:P87322|uniprotkb:Q6LC13|uniprotkb:A0A1D8PMK1	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:erk1_canal(display_long)|uniprotkb:CEK1(gene name)|psi-mi:CEK1(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:MAP kinase 1(gene name synonym)|uniprotkb:CaO19.10404(orf name)|uniprotkb:CaO19.2886(orf name)|uniprotkb:CAALFM_C406480CA(locus name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:237561(canal)|taxid:237561("Candida albicans (strain SC5314 / ATCC MYA-2876)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8872094|imex:IM-21742-34	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_715542.2|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0030447"(filamentous growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0036170"(filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:0036180"(filamentous growth of a population of unicellular organisms in response to biotic stimulus)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:1900445"(positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus)|go:"GO:1990277"(parasexual conjugation with cellular fusion)	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	-	crc64:0435BDA0196B2D6F	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2017/03/30	rogid:gfbxkgS8l9FDVkxy4SHurMzw9iI237561	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:62761DB165200AAA|rigid:x235sP8F7tL5t0MnBbPOCa3ZGWY	false	-	sufficient binding region:?-?(IPR021106)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5A1D3	uniprotkb:P06784	intact:EBI-8783371|uniprotkb:O13435|uniprotkb:P28869|uniprotkb:P87079|uniprotkb:P87080|uniprotkb:P87081|uniprotkb:P87082|uniprotkb:P87083|uniprotkb:P87084|uniprotkb:P87085|uniprotkb:P87086|uniprotkb:P87322|uniprotkb:Q6LC13|uniprotkb:A0A1D8PMK1	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:erk1_canal(display_long)|uniprotkb:CEK1(gene name)|psi-mi:CEK1(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:MAP kinase 1(gene name synonym)|uniprotkb:CaO19.10404(orf name)|uniprotkb:CaO19.2886(orf name)|uniprotkb:CAALFM_C406480CA(locus name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:237561(canal)|taxid:237561("Candida albicans (strain SC5314 / ATCC MYA-2876)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8872094|imex:IM-21742-34	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_715542.2|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0030447"(filamentous growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0036170"(filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:0036180"(filamentous growth of a population of unicellular organisms in response to biotic stimulus)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:1900445"(positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus)|go:"GO:1990277"(parasexual conjugation with cellular fusion)	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	-	crc64:C8A75899CFBE8BDE	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2017/03/30	rogid:gfbxkgS8l9FDVkxy4SHurMzw9iI237561	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:62761DB165200AAA|rigid:x235sP8F7tL5t0MnBbPOCa3ZGWY	false	-	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06784	uniprotkb:C5M3M0	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	intact:EBI-8785223|ensemblfungi:EER35920	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:c5m3m0_cantt(display_long)|uniprotkb:CTRG_00659(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:294747(cantt)|taxid:294747("Candida tropicalis (strain ATCC MYA-3404 / T1)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8872129|imex:IM-21742-35	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	refseq:XP_002545878.1|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:CTRG_00659(gene)|ensemblfungi:EER35920(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR011009(Protein kinase-like)	-	crc64:C8A75899CFBE8BDE	-	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	rogid:oSwgGn0Wqy34kNXIJR5X0SF4M4k294747	intact-crc:CFCD7A5C35E4BB05|rigid:o6+qM07a9jczbvOLCDsdxQS3JX8	false	mutation:359-359,363-363|maltose binding protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A5E0P6	uniprotkb:P06784	intact:EBI-8785291|ensemblfungi:EDK45004	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:a5e0p6_lodel(display_long)|uniprotkb:LELG_03183(orf name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:379508(lodel)|taxid:379508("Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8872146|imex:IM-21742-36	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_001525255.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:EDK45004(transcript)|ensemblfungi:LELG_03183(gene)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	-	crc64:C8A75899CFBE8BDE	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:D6igUnRhcb9HKgtiOBlRF09fKu0379508	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:80CD37ABEA1496E2|rigid:x5VWHu4Ill4qXrxV/FGeJPS9Hf0	false	-	mutation:359-359,363-363|maltose binding protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P27638	uniprotkb:P06784	intact:EBI-2104356|ensemblfungi:"SPAC31G5.09c.1:pep"	intact:EBI-18389|uniprotkb:D6VRJ2|ensemblfungi:YDL159W	psi-mi:spk1_schpo(display_long)|uniprotkb:spk1(gene name)|psi-mi:spk1(display_short)|uniprotkb:SPAC31G5.09c(orf name)	psi-mi:ste7_yeast(display_long)|uniprotkb:STE7(gene name)|psi-mi:STE7(display_short)|uniprotkb:D1525(orf name)|uniprotkb:YDL159W(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8872174|imex:IM-21742-37	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SPO-112409|reactome:R-SPO-198753|reactome:R-SPO-202670|reactome:R-SPO-3371453|reactome:R-SPO-5673001|reactome:R-SPO-110056|reactome:R-SPO-112411|reactome:R-SPO-445144|reactome:R-SPO-5674135|reactome:R-SPO-5674499|reactome:R-SPO-170968|refseq:NP_594009.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-2559582|reactome:R-SPO-375165|reactome:R-SPO-5668599|reactome:R-SPO-5675221|reactome:R-SPO-5687128|reactome:R-SPO-881907|reactome:R-SPO-6798695|reactome:R-SPO-450341|reactome:R-SPO-111995|reactome:R-SPO-437239|reactome:R-SPO-9634635|ensemblfungi:SPAC31G5.09c(gene)|ensemblfungi:SPAC31G5.09c.1(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	refseq:NP_010122.1|sgd:S000002318|reactome:R-SCE-112411|reactome:R-SCE-445144|reactome:R-SCE-5674135|reactome:R-SCE-5674499|ensemblfungi:YDL159W(gene)|ensemblfungi:YDL159W_mRNA(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0043332"(mating projection tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-110056|dip:DIP-9N|mint:P06784	-	-	crc64:C8A75899CFBE8BDE	figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:qH6Zs+UeAarxVUH1p86FeFXkpcY284812	rogid:dyC78MRkFAByOXZMkYmZ8nul+dU559292	intact-crc:4E28B3D9C624FDA9|rigid:rTF/Zd5b9dZ1YrAAdAO3pPCE4dk	false	-	maltose binding protein tag:?-?|mutation:359-359,363-363	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32917	uniprotkb:Q5A1D3	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	intact:EBI-8783371|uniprotkb:O13435|uniprotkb:P28869|uniprotkb:P87079|uniprotkb:P87080|uniprotkb:P87081|uniprotkb:P87082|uniprotkb:P87083|uniprotkb:P87084|uniprotkb:P87085|uniprotkb:P87086|uniprotkb:P87322|uniprotkb:Q6LC13|uniprotkb:A0A1D8PMK1	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:erk1_canal(display_long)|uniprotkb:CEK1(gene name)|psi-mi:CEK1(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:MAP kinase 1(gene name synonym)|uniprotkb:CaO19.10404(orf name)|uniprotkb:CaO19.2886(orf name)|uniprotkb:CAALFM_C406480CA(locus name)	psi-mi:"MI:0096"(pull down)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:237561(canal)|taxid:237561("Candida albicans (strain SC5314 / ATCC MYA-2876)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783369|imex:IM-21742-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_715542.2|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0030447"(filamentous growth)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0036170"(filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:0036180"(filamentous growth of a population of unicellular organisms in response to biotic stimulus)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:1900445"(positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus)|go:"GO:1990277"(parasexual conjugation with cellular fusion)	-	crc64:0435BDA0196B2D6F	-	figure legend:Suppl. Fig. S4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2017/03/30	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	rogid:gfbxkgS8l9FDVkxy4SHurMzw9iI237561	intact-crc:465163748EAFA436|rigid:hL+GXXOy1R+j2y6zpNmj5RKtHqg	false	sufficient binding region:?-?(IPR021651)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:C8V7D1	uniprotkb:P32917	intact:EBI-8783425|ensemblfungi:CBF75537	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:c8v7d1_emeni(display_long)|uniprotkb:mpkB(gene name)|psi-mi:mpkB(display_short)|uniprotkb:ANIA_03719(orf name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0096"(pull down)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:227321(emeni)|taxid:227321(Emericella nidulans)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783452|imex:IM-21742-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0010914"(positive regulation of sterigmatocystin biosynthetic process)|go:"GO:0030437"(ascospore formation)|go:"GO:0033246"(positive regulation of penicillin metabolic process)|go:"GO:0034293"(sexual sporulation)|go:"GO:0035146"(tube fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042318"(penicillin biosynthetic process)|go:"GO:0045461"(sterigmatocystin biosynthetic process)|go:"GO:0075296"(positive regulation of ascospore formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900376"(regulation of secondary metabolite biosynthetic process)|go:"GO:0005737"(cytoplasm)|ensemblfungi:ANIA_03719(gene)|ensemblfungi:CBF75537(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000909"(sporocarp development involved in sexual reproduction)|go:"GO:0001411"(hyphal tip)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	-	crc64:0435BDA0196B2D6F	figure legend:Suppl. Fig. S4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:dUbXGpALcJWdYArIl4x+4GPRwa0227321	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:7C8DA4738D66BACE|rigid:VFoxV/+xJj0Sm4KWxZCbKbMbmuo	false	-	glutathione s tranferase tag:?-?|sufficient binding region:?-?(IPR021651)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-8783462	uniprotkb:P32917	-	intact:EBI-18373|uniprotkb:D6VS89|ensemblfungi:YDR103W	psi-mi:q1k6i1_neucr(display_short)|psi-mi:EBI-8783462(display_long)|uniprotkb:NCU02393(orf name)	psi-mi:ste5_yeast(display_long)|uniprotkb:STE5(gene name)|psi-mi:STE5(display_short)|uniprotkb:NUL3(gene name synonym)|uniprotkb:YDR103W(locus name)|uniprotkb:YD8557.12(orf name)	psi-mi:"MI:0096"(pull down)	Coyle et al. (2013)	pubmed:23953117|imex:IM-21742	taxid:367110(neucr)|taxid:367110("Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8783476|imex:IM-21742-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q1K6I1(uniprot-removed-ac)	refseq:NP_010388.1|sgd:S000002510|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019900"(kinase binding)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070867"(mating projection tip membrane)|interpro:IPR021106|interpro:IPR021651|interpro:IPR038382|rcsb pdb:2KGN|rcsb pdb:2L4U|rcsb pdb:3FZE|rcsb pdb:4F2H|go:"GO:0005886"(plasma membrane)|ensemblfungi:YDR103W(gene)|ensemblfungi:YDR103W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-858N|mint:P32917	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	crc64:0435BDA0196B2D6F	figure legend:Suppl. Fig. S4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/26	2014/10/16	rogid:mKyMj5sK5mGpuI3iv2wlEBK2llw367110	rogid:4AGoihw1xiRnhpu4/VuycJzCLaE559292	intact-crc:03235A6D1D600273|rigid:mBgbx3+rsxFtIiKdZ1oa4cXcDtg	false	-	glutathione s tranferase tag:?-?|sufficient binding region:?-?(IPR021651)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)