#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O43663-1	uniprotkb:O43663-1	intact:EBI-1503979|ensembl:ENSP00000377793	intact:EBI-1503979|ensembl:ENSP00000377793	psi-mi:o43663-1(display_long)|uniprotkb:PRC1(gene name)|psi-mi:PRC1(display_short)	psi-mi:o43663-1(display_long)|uniprotkb:PRC1(gene name)|psi-mi:PRC1(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Subramanian et al. (2013)	pubmed:23870126|imex:IM-21534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8788400|imex:IM-21534-4|wwpdb:4L3I	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198901(gene)|ensembl:ENST00000394249(transcript)|intact:EBI-741137(isoform-parent)	ensembl:ENSG00000198901(gene)|ensembl:ENST00000394249(transcript)|intact:EBI-741137(isoform-parent)	-	-	-	figure legend:Supp Table 1|3d-resolution:3.6A|3d-r-factors:Rwork = 0.26 Rfree = 0.3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/04	2014/10/16	rogid:AV2d6TYVsFn2J598pi/GmPdgK7A9606	rogid:AV2d6TYVsFn2J598pi/GmPdgK7A9606	intact-crc:CAD4A4C566D6E417|rigid:9bUtXba+SBXWvQsjmE2XJfXFAvQ	false	sufficient binding region:1-486|L-selenomethionine:?-?	sufficient binding region:1-486|L-selenomethionine:?-?	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43663-1	uniprotkb:O43663-1	intact:EBI-1503979|ensembl:ENSP00000377793	intact:EBI-1503979|ensembl:ENSP00000377793	psi-mi:o43663-1(display_long)|uniprotkb:PRC1(gene name)|psi-mi:PRC1(display_short)	psi-mi:o43663-1(display_long)|uniprotkb:PRC1(gene name)|psi-mi:PRC1(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Subramanian et al. (2013)	pubmed:23870126|imex:IM-21534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8788269|wwpdb:4L6Y|imex:IM-21534-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198901(gene)|ensembl:ENST00000394249(transcript)|intact:EBI-741137(isoform-parent)	ensembl:ENSG00000198901(gene)|ensembl:ENST00000394249(transcript)|intact:EBI-741137(isoform-parent)	-	-	-	figure legend:Supp Table 1|3d-resolution:3.3A|3d-r-factors:Rwork = 0.28 Rfree = 0.31|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/04	2014/10/16	rogid:AV2d6TYVsFn2J598pi/GmPdgK7A9606	rogid:AV2d6TYVsFn2J598pi/GmPdgK7A9606	intact-crc:7FCE8747D81F71DE|rigid:9bUtXba+SBXWvQsjmE2XJfXFAvQ	false	sufficient binding region:1-486	sufficient binding region:1-486	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43663-1	uniprotkb:O43663-1	intact:EBI-1503979|ensembl:ENSP00000377793	intact:EBI-1503979|ensembl:ENSP00000377793	psi-mi:o43663-1(display_long)|uniprotkb:PRC1(gene name)|psi-mi:PRC1(display_short)	psi-mi:o43663-1(display_long)|uniprotkb:PRC1(gene name)|psi-mi:PRC1(display_short)	psi-mi:"MI:0071"(molecular sieving)	Subramanian et al. (2013)	pubmed:23870126|imex:IM-21534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8800565|imex:IM-21534-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198901(gene)|ensembl:ENST00000394249(transcript)|intact:EBI-741137(isoform-parent)	ensembl:ENSG00000198901(gene)|ensembl:ENST00000394249(transcript)|intact:EBI-741137(isoform-parent)	-	-	-	figure legend:Supp. Fig. 1G-I|comment:A SNAP sequence was inserted between the TEV cleavage site and the N terminus of PRC1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/04	2014/10/16	rogid:AV2d6TYVsFn2J598pi/GmPdgK7A9606	rogid:AV2d6TYVsFn2J598pi/GmPdgK7A9606	intact-crc:EAB0809277182488|rigid:9bUtXba+SBXWvQsjmE2XJfXFAvQ	false	necessary binding region:19-40|sufficient binding region:19-486	necessary binding region:19-40|sufficient binding region:19-486	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43663-1	uniprotkb:O95239	intact:EBI-1503979|ensembl:ENSP00000377793	intact:EBI-1057516|uniprotkb:Q86TN3|uniprotkb:Q86XX7|uniprotkb:Q9NNY6|uniprotkb:Q9NY24|uniprotkb:Q9UMW3|uniprotkb:D3DVU4|uniprotkb:B2R7V5|ensembl:ENSP00000363524	psi-mi:o43663-1(display_long)|uniprotkb:PRC1(gene name)|psi-mi:PRC1(display_short)	psi-mi:kif4a_human(display_long)|uniprotkb:KIF4A(gene name)|psi-mi:KIF4A(display_short)|uniprotkb:KIF4(gene name synonym)|uniprotkb:Chromokinesin-A(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Subramanian et al. (2013)	pubmed:23870126|imex:IM-21534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8788286|imex:IM-21534-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198901(gene)|ensembl:ENST00000394249(transcript)|intact:EBI-741137(isoform-parent)	refseq:NP_036442.3|ensembl:ENSG00000090889(gene)|ensembl:ENST00000374403(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|interpro:IPR027417|interpro:IPR036961|mint:O95239|rcsb pdb:6OYL|reactome:R-HSA-2132295|reactome:R-HSA-437239|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0006996"(organelle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030496"(midbody)|go:"GO:0046872"(metal ion binding)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821	go:"GO:0035371"(microtubule plus-end)	-	-	figure legend:Supp. Fig. 1 G-I|comment:A SNAP sequence was inserted between the TEV cleavage site and the N terminus of PRC1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-htert_rpe1)|taxid:9606(Homo sapiens)	-	2013/10/04	2014/10/16	rogid:AV2d6TYVsFn2J598pi/GmPdgK7A9606	rogid:Dn015O/tY/LZAnI5oVnvTVQH3Zk9606	intact-crc:68A329D43DF8378F|rigid:QIcJ0Os+LwgX7i7anViqT8pa1Dw	false	alexa 546 label:n-n	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O43663-1	uniprotkb:O95239-1	intact:EBI-1503979|ensembl:ENSP00000377793	intact:EBI-8788226|ensembl:ENSP00000363524	psi-mi:o43663-1(display_long)|uniprotkb:PRC1(gene name)|psi-mi:PRC1(display_short)	psi-mi:o95239-1(display_long)|uniprotkb:KIF4A(gene name)|psi-mi:KIF4A(display_short)|uniprotkb:KIF4(gene name synonym)|uniprotkb:Chromokinesin-A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Subramanian et al. (2013)	pubmed:23870126|imex:IM-21534	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8788234|imex:IM-21534-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198901(gene)|ensembl:ENST00000394249(transcript)|intact:EBI-741137(isoform-parent)	intact:EBI-1057516(isoform-parent)|ensembl:ENSG00000090889(gene)|ensembl:ENST00000374403(transcript)	-	-	-	figure legend:Fig 1B, 6B-D|comment:Weak binding was achieved with a 1–117 PCR1 construct.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.0x10^-7(molar)	2013/10/04	2014/10/16	rogid:AV2d6TYVsFn2J598pi/GmPdgK7A9606	rogid:Dn015O/tY/LZAnI5oVnvTVQH3Zk9606	intact-crc:9B4BBC803304BE8B|rigid:QIcJ0Os+LwgX7i7anViqT8pa1Dw	false	necessary binding region:20-66|his tag:n-n|sufficient binding region:1-231	sufficient binding region:733-1232	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)