#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8NCD3 uniprotkb:Q8NCD3 intact:EBI-719429|intact:EBI-2561961|uniprotkb:A8IRH5|uniprotkb:Q9BUT2|uniprotkb:Q9NSL8|uniprotkb:B4DWR0|uniprotkb:B4DZV4|intact:EBI-28976688|ensembl:ENSP00000414109 intact:EBI-719429|intact:EBI-2561961|uniprotkb:A8IRH5|uniprotkb:Q9BUT2|uniprotkb:Q9NSL8|uniprotkb:B4DWR0|uniprotkb:B4DZV4|intact:EBI-28976688|ensembl:ENSP00000414109 psi-mi:hjurp_human(display_long)|uniprotkb:FAKTS(gene name synonym)|uniprotkb:URLC9(gene name synonym)|uniprotkb:14-3-3-associated AKT substrate(gene name synonym)|uniprotkb:Fetal liver-expressing gene 1 protein(gene name synonym)|uniprotkb:Up-regulated in lung cancer 9(gene name synonym)|uniprotkb:HJURP(gene name)|psi-mi:HJURP(display_short)|uniprotkb:FLEG1(gene name synonym) psi-mi:hjurp_human(display_long)|uniprotkb:FAKTS(gene name synonym)|uniprotkb:URLC9(gene name synonym)|uniprotkb:14-3-3-associated AKT substrate(gene name synonym)|uniprotkb:Fetal liver-expressing gene 1 protein(gene name synonym)|uniprotkb:Up-regulated in lung cancer 9(gene name synonym)|uniprotkb:HJURP(gene name)|psi-mi:HJURP(display_short)|uniprotkb:FLEG1(gene name synonym) psi-mi:"MI:0090"(protein complementation assay) Zasadzińska et al. (2013) pubmed:23771058|imex:IM-21694 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8846556|imex:IM-21694-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269891.1|refseq:NP_001269892.1|refseq:NP_060880.3|ensembl:ENSP00000414109|ensembl:ENST00000432087|ensembl:ENSP00000407208|ensembl:ENST00000441687|ensembl:ENSP00000401944|ensembl:ENSG00000123485(gene)|ensembl:ENST00000411486(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0051101"(regulation of DNA binding)|interpro:IPR018465|interpro:IPR021052|interpro:IPR022102|mint:Q8NCD3|rcsb pdb:3R45|reactome:R-HSA-606279|dip:DIP-53282N refseq:NP_001269891.1|refseq:NP_001269892.1|refseq:NP_060880.3|ensembl:ENSP00000414109|ensembl:ENST00000432087|ensembl:ENSP00000407208|ensembl:ENST00000441687|ensembl:ENSP00000401944|ensembl:ENSG00000123485(gene)|ensembl:ENST00000411486(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0051101"(regulation of DNA binding)|interpro:IPR018465|interpro:IPR021052|interpro:IPR022102|mint:Q8NCD3|rcsb pdb:3R45|reactome:R-HSA-606279|dip:DIP-53282N - - - figure legend:f2b f2c f2d f2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2013/11/08 2014/10/16 rogid:pUujTbXXH/IPt8rusd4Nef0rfrk9606 rogid:pUujTbXXH/IPt8rusd4Nef0rfrk9606 intact-crc:D3310E9716C563DF|rigid:1JmUI7GBYFt3mQg4XfgFSZRIMKo false sufficient binding region:352-748|fusion protein:?-? green fluorescent protein tag:?-?|sufficient binding region:482-748 - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q8NCD3 uniprotkb:Q8NCD3 intact:EBI-719429|intact:EBI-2561961|uniprotkb:A8IRH5|uniprotkb:Q9BUT2|uniprotkb:Q9NSL8|uniprotkb:B4DWR0|uniprotkb:B4DZV4|intact:EBI-28976688|ensembl:ENSP00000414109 intact:EBI-719429|intact:EBI-2561961|uniprotkb:A8IRH5|uniprotkb:Q9BUT2|uniprotkb:Q9NSL8|uniprotkb:B4DWR0|uniprotkb:B4DZV4|intact:EBI-28976688|ensembl:ENSP00000414109 psi-mi:hjurp_human(display_long)|uniprotkb:FAKTS(gene name synonym)|uniprotkb:URLC9(gene name synonym)|uniprotkb:14-3-3-associated AKT substrate(gene name synonym)|uniprotkb:Fetal liver-expressing gene 1 protein(gene name synonym)|uniprotkb:Up-regulated in lung cancer 9(gene name synonym)|uniprotkb:HJURP(gene name)|psi-mi:HJURP(display_short)|uniprotkb:FLEG1(gene name synonym) psi-mi:hjurp_human(display_long)|uniprotkb:FAKTS(gene name synonym)|uniprotkb:URLC9(gene name synonym)|uniprotkb:14-3-3-associated AKT substrate(gene name synonym)|uniprotkb:Fetal liver-expressing gene 1 protein(gene name synonym)|uniprotkb:Up-regulated in lung cancer 9(gene name synonym)|uniprotkb:HJURP(gene name)|psi-mi:HJURP(display_short)|uniprotkb:FLEG1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Zasadzińska et al. (2013) pubmed:23771058|imex:IM-21694 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846623|imex:IM-21694-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269891.1|refseq:NP_001269892.1|refseq:NP_060880.3|ensembl:ENSP00000414109|ensembl:ENST00000432087|ensembl:ENSP00000407208|ensembl:ENST00000441687|ensembl:ENSP00000401944|ensembl:ENSG00000123485(gene)|ensembl:ENST00000411486(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0051101"(regulation of DNA binding)|interpro:IPR018465|interpro:IPR021052|interpro:IPR022102|mint:Q8NCD3|rcsb pdb:3R45|reactome:R-HSA-606279|dip:DIP-53282N refseq:NP_001269891.1|refseq:NP_001269892.1|refseq:NP_060880.3|ensembl:ENSP00000414109|ensembl:ENST00000432087|ensembl:ENSP00000407208|ensembl:ENST00000441687|ensembl:ENSP00000401944|ensembl:ENSG00000123485(gene)|ensembl:ENST00000411486(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0051101"(regulation of DNA binding)|interpro:IPR018465|interpro:IPR021052|interpro:IPR022102|mint:Q8NCD3|rcsb pdb:3R45|reactome:R-HSA-606279|dip:DIP-53282N - - - figure legend:f3b f3c sf1b|comment:"Based on size-exclusion chromatography, the Stokes radius of His-HJURP482-end was calculated as 5.46nm (Figure 3B and C; Supplementary Figure S1B), which is twice as large as the expected 2.48nm Stokes radius of a 30-kDa globular protein. This larger than expected Stokes radius may indicate either that HJURP482-end is an elongated protein or that it exists as a multimer."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/11/08 2014/10/16 rogid:pUujTbXXH/IPt8rusd4Nef0rfrk9606 rogid:pUujTbXXH/IPt8rusd4Nef0rfrk9606 intact-crc:BAD7ABBAD57FCF33|rigid:1JmUI7GBYFt3mQg4XfgFSZRIMKo false binding-associated region:482-748|his tag:?-? his tag:?-?|binding-associated region:482-748 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NCD3 uniprotkb:Q8NCD3 intact:EBI-719429|intact:EBI-2561961|uniprotkb:A8IRH5|uniprotkb:Q9BUT2|uniprotkb:Q9NSL8|uniprotkb:B4DWR0|uniprotkb:B4DZV4|intact:EBI-28976688|ensembl:ENSP00000414109 intact:EBI-719429|intact:EBI-2561961|uniprotkb:A8IRH5|uniprotkb:Q9BUT2|uniprotkb:Q9NSL8|uniprotkb:B4DWR0|uniprotkb:B4DZV4|intact:EBI-28976688|ensembl:ENSP00000414109 psi-mi:hjurp_human(display_long)|uniprotkb:FAKTS(gene name synonym)|uniprotkb:URLC9(gene name synonym)|uniprotkb:14-3-3-associated AKT substrate(gene name synonym)|uniprotkb:Fetal liver-expressing gene 1 protein(gene name synonym)|uniprotkb:Up-regulated in lung cancer 9(gene name synonym)|uniprotkb:HJURP(gene name)|psi-mi:HJURP(display_short)|uniprotkb:FLEG1(gene name synonym) psi-mi:hjurp_human(display_long)|uniprotkb:FAKTS(gene name synonym)|uniprotkb:URLC9(gene name synonym)|uniprotkb:14-3-3-associated AKT substrate(gene name synonym)|uniprotkb:Fetal liver-expressing gene 1 protein(gene name synonym)|uniprotkb:Up-regulated in lung cancer 9(gene name synonym)|uniprotkb:HJURP(gene name)|psi-mi:HJURP(display_short)|uniprotkb:FLEG1(gene name synonym) psi-mi:"MI:0096"(pull down) Zasadzińska et al. (2013) pubmed:23771058|imex:IM-21694 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846669|imex:IM-21694-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269891.1|refseq:NP_001269892.1|refseq:NP_060880.3|ensembl:ENSP00000414109|ensembl:ENST00000432087|ensembl:ENSP00000407208|ensembl:ENST00000441687|ensembl:ENSP00000401944|ensembl:ENSG00000123485(gene)|ensembl:ENST00000411486(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0051101"(regulation of DNA binding)|interpro:IPR018465|interpro:IPR021052|interpro:IPR022102|mint:Q8NCD3|rcsb pdb:3R45|reactome:R-HSA-606279|dip:DIP-53282N refseq:NP_001269891.1|refseq:NP_001269892.1|refseq:NP_060880.3|ensembl:ENSP00000414109|ensembl:ENST00000432087|ensembl:ENSP00000407208|ensembl:ENST00000441687|ensembl:ENSP00000401944|ensembl:ENSG00000123485(gene)|ensembl:ENST00000411486(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0051101"(regulation of DNA binding)|interpro:IPR018465|interpro:IPR021052|interpro:IPR022102|mint:Q8NCD3|rcsb pdb:3R45|reactome:R-HSA-606279|dip:DIP-53282N - - - figure legend:f3e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/11/08 2014/10/16 rogid:pUujTbXXH/IPt8rusd4Nef0rfrk9606 rogid:pUujTbXXH/IPt8rusd4Nef0rfrk9606 intact-crc:B834C5D592B0F4C4|rigid:1JmUI7GBYFt3mQg4XfgFSZRIMKo false maltose binding protein tag:?-?|sufficient binding region:482-748 his tag:?-?|sufficient binding region:482-748 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NCD3 uniprotkb:Q8NCD3 intact:EBI-719429|intact:EBI-2561961|uniprotkb:A8IRH5|uniprotkb:Q9BUT2|uniprotkb:Q9NSL8|uniprotkb:B4DWR0|uniprotkb:B4DZV4|intact:EBI-28976688|ensembl:ENSP00000414109 intact:EBI-719429|intact:EBI-2561961|uniprotkb:A8IRH5|uniprotkb:Q9BUT2|uniprotkb:Q9NSL8|uniprotkb:B4DWR0|uniprotkb:B4DZV4|intact:EBI-28976688|ensembl:ENSP00000414109 psi-mi:hjurp_human(display_long)|uniprotkb:FAKTS(gene name synonym)|uniprotkb:URLC9(gene name synonym)|uniprotkb:14-3-3-associated AKT substrate(gene name synonym)|uniprotkb:Fetal liver-expressing gene 1 protein(gene name synonym)|uniprotkb:Up-regulated in lung cancer 9(gene name synonym)|uniprotkb:HJURP(gene name)|psi-mi:HJURP(display_short)|uniprotkb:FLEG1(gene name synonym) psi-mi:hjurp_human(display_long)|uniprotkb:FAKTS(gene name synonym)|uniprotkb:URLC9(gene name synonym)|uniprotkb:14-3-3-associated AKT substrate(gene name synonym)|uniprotkb:Fetal liver-expressing gene 1 protein(gene name synonym)|uniprotkb:Up-regulated in lung cancer 9(gene name synonym)|uniprotkb:HJURP(gene name)|psi-mi:HJURP(display_short)|uniprotkb:FLEG1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zasadzińska et al. (2013) pubmed:23771058|imex:IM-21694 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8846694|imex:IM-21694-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269891.1|refseq:NP_001269892.1|refseq:NP_060880.3|ensembl:ENSP00000414109|ensembl:ENST00000432087|ensembl:ENSP00000407208|ensembl:ENST00000441687|ensembl:ENSP00000401944|ensembl:ENSG00000123485(gene)|ensembl:ENST00000411486(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0051101"(regulation of DNA binding)|interpro:IPR018465|interpro:IPR021052|interpro:IPR022102|mint:Q8NCD3|rcsb pdb:3R45|reactome:R-HSA-606279|dip:DIP-53282N refseq:NP_001269891.1|refseq:NP_001269892.1|refseq:NP_060880.3|ensembl:ENSP00000414109|ensembl:ENST00000432087|ensembl:ENSP00000407208|ensembl:ENST00000441687|ensembl:ENSP00000401944|ensembl:ENSG00000123485(gene)|ensembl:ENST00000411486(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0051101"(regulation of DNA binding)|interpro:IPR018465|interpro:IPR021052|interpro:IPR022102|mint:Q8NCD3|rcsb pdb:3R45|reactome:R-HSA-606279|dip:DIP-53282N - - - figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2013/11/08 2014/10/16 rogid:pUujTbXXH/IPt8rusd4Nef0rfrk9606 rogid:pUujTbXXH/IPt8rusd4Nef0rfrk9606 intact-crc:33F3CD6929D516A7|rigid:1JmUI7GBYFt3mQg4XfgFSZRIMKo false sufficient binding region:482-748|green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)