#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P11938	uniprotkb:P29539	intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W	intact:EBI-2083307|uniprotkb:D6VQS1|uniprotkb:P89507|ensemblfungi:YBR275C	psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym)	psi-mi:rif1_yeast(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:RAP1-interacting factor 1(gene name synonym)|uniprotkb:YBR1743(orf name)|uniprotkb:YBR275C(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Shi et al. (2013)	imex:IM-21427|pubmed:23746845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8765984|imex:IM-21427-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938	sgd:S000000479|refseq:NP_009834.4|dip:DIP-801N|mint:P29539|ensemblfungi:YBR275C(gene)|ensemblfungi:YBR275C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0016233"(telomere capping)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:0101018"(negative regulation of mitotic DNA replication initiation from late origin)|interpro:IPR022031|interpro:IPR028566|rcsb pdb:4BJS|rcsb pdb:4BJT|rcsb pdb:5NVR|rcsb pdb:5NW5	-	crc64:67C4AFB03B3C0713	-	figure legend:Fig. 2H, Supp. Fig. 3C, 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kcat:2.0x10^-5(molar)	2013/09/19	2014/10/16	rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292	rogid:zQ0Ljkemo6SMWT8CreVFclqCa7k559292	intact-crc:DDED840E704AEE21|rigid:R/jIMl1s6x9AdMV0i5oDzEOcGs4	false	sufficient binding region:672-827	mutation decreasing interaction strength:1905-1905|necessary binding region:1709-1765|sufficient binding region:1709-1916	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06208	uniprotkb:P11938	intact:EBI-15199|uniprotkb:E9P8Y1|uniprotkb:D6VZ87|ensemblfungi:YLR453C	intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W	psi-mi:rif2_yeast(display_long)|uniprotkb:RIF2(gene name)|psi-mi:RIF2(display_short)|uniprotkb:RAP1-interacting factor 2(gene name synonym)|uniprotkb:YLR453C(locus name)	psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Shi et al. (2013)	imex:IM-21427|pubmed:23746845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8765989|imex:IM-21427-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004445|refseq:NP_013558.3|ensemblfungi:YLR453C(gene)|ensemblfungi:YLR453C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070187"(shelterin complex)|rcsb pdb:4BJ1|rcsb pdb:4BJ5|rcsb pdb:4BJ6|dip:DIP-4290N	sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938	-	-	crc64:67C4AFB03B3C0713	figure legend:Fig. 1G-I|comment:"A Rif2 RBM construct  (30–49) bound Rap1 with an affinity of 30 uM, a Rif2 construct retaining the AAA+ interface (61-371), bound Rap with an affinity of 50 uM"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.0x10^-5(molar)	2013/09/19	2014/10/16	rogid:DKgvGLSUFxdJ8D4kLgAXZiNtimQ559292	rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292	intact-crc:8E683D8F2FB10C52|rigid:LO8gF45Q/Fm12oU0cWF7h1SSKkA	false	sufficient binding region:61-371|sufficient binding region:30-49	sufficient binding region:672-827|sufficient binding region:672-827	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06208	uniprotkb:P11938	intact:EBI-15199|uniprotkb:E9P8Y1|uniprotkb:D6VZ87|ensemblfungi:YLR453C	intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W	psi-mi:rif2_yeast(display_long)|uniprotkb:RIF2(gene name)|psi-mi:RIF2(display_short)|uniprotkb:RAP1-interacting factor 2(gene name synonym)|uniprotkb:YLR453C(locus name)	psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym)	psi-mi:"MI:0982"(electrophoretic mobility-based method)	Shi et al. (2013)	imex:IM-21427|pubmed:23746845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8768969|imex:IM-21427-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004445|refseq:NP_013558.3|ensemblfungi:YLR453C(gene)|ensemblfungi:YLR453C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070187"(shelterin complex)|rcsb pdb:4BJ1|rcsb pdb:4BJ5|rcsb pdb:4BJ6|dip:DIP-4290N	sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938	-	-	crc64:67C4AFB03B3C0713	figure legend:Supp. Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/19	2014/10/16	rogid:DKgvGLSUFxdJ8D4kLgAXZiNtimQ559292	rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292	intact-crc:512725450FC1BC5F|rigid:LO8gF45Q/Fm12oU0cWF7h1SSKkA	false	sufficient binding region:2-395	sufficient binding region:672-827	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q06208	uniprotkb:P11938	intact:EBI-15199|uniprotkb:E9P8Y1|uniprotkb:D6VZ87|ensemblfungi:YLR453C	intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W	psi-mi:rif2_yeast(display_long)|uniprotkb:RIF2(gene name)|psi-mi:RIF2(display_short)|uniprotkb:RAP1-interacting factor 2(gene name synonym)|uniprotkb:YLR453C(locus name)	psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Shi et al. (2013)	imex:IM-21427|pubmed:23746845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8768991|imex:IM-21427-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004445|refseq:NP_013558.3|ensemblfungi:YLR453C(gene)|ensemblfungi:YLR453C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070187"(shelterin complex)|rcsb pdb:4BJ1|rcsb pdb:4BJ5|rcsb pdb:4BJ6|dip:DIP-4290N	sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938	-	-	crc64:67C4AFB03B3C0713	figure legend:Supp. Fig. 2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/19	2014/10/16	rogid:DKgvGLSUFxdJ8D4kLgAXZiNtimQ559292	rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292	intact-crc:939D556BF6804FC9|rigid:LO8gF45Q/Fm12oU0cWF7h1SSKkA	false	sufficient binding region:2-395|glutathione s tranferase tag:n-n	strep tag:?-?|sufficient binding region:672-827	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P11938	uniprotkb:Q06208	intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W	intact:EBI-15199|uniprotkb:E9P8Y1|uniprotkb:D6VZ87|ensemblfungi:YLR453C	psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym)	psi-mi:rif2_yeast(display_long)|uniprotkb:RIF2(gene name)|psi-mi:RIF2(display_short)|uniprotkb:RAP1-interacting factor 2(gene name synonym)|uniprotkb:YLR453C(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Shi et al. (2013)	imex:IM-21427|pubmed:23746845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006858|imex:IM-21427-8|wwpdb:4BJ6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938	sgd:S000004445|refseq:NP_013558.3|ensemblfungi:YLR453C(gene)|ensemblfungi:YLR453C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070187"(shelterin complex)|rcsb pdb:4BJ1|rcsb pdb:4BJ5|rcsb pdb:4BJ6|dip:DIP-4290N	-	crc64:67C4AFB03B3C0713	-	3d-resolution:3.3A|3d-r-factors:R = 0.17 Rwork = 0.17 Rfree = 0.2|figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/19	2014/10/16	rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292	rogid:DKgvGLSUFxdJ8D4kLgAXZiNtimQ559292	intact-crc:9AE31FA14A6D06F5|rigid:LO8gF45Q/Fm12oU0cWF7h1SSKkA	false	sufficient binding region:627-827	sufficient binding region:36-48	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11938	uniprotkb:Q06208	intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W	intact:EBI-15199|uniprotkb:E9P8Y1|uniprotkb:D6VZ87|ensemblfungi:YLR453C	psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym)	psi-mi:rif2_yeast(display_long)|uniprotkb:RIF2(gene name)|psi-mi:RIF2(display_short)|uniprotkb:RAP1-interacting factor 2(gene name synonym)|uniprotkb:YLR453C(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Shi et al. (2013)	imex:IM-21427|pubmed:23746845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006858|imex:IM-21427-8|wwpdb:4BJ6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938	sgd:S000004445|refseq:NP_013558.3|ensemblfungi:YLR453C(gene)|ensemblfungi:YLR453C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070187"(shelterin complex)|rcsb pdb:4BJ1|rcsb pdb:4BJ5|rcsb pdb:4BJ6|dip:DIP-4290N	-	crc64:67C4AFB03B3C0713	-	3d-resolution:3.3A|3d-r-factors:R = 0.17 Rwork = 0.17 Rfree = 0.2|figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/19	2014/10/16	rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292	rogid:DKgvGLSUFxdJ8D4kLgAXZiNtimQ559292	intact-crc:9AE31FA14A6D06F5|rigid:LO8gF45Q/Fm12oU0cWF7h1SSKkA	false	sufficient binding region:627-827	sufficient binding region:35-395	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06208	uniprotkb:P11938	intact:EBI-15199|uniprotkb:E9P8Y1|uniprotkb:D6VZ87|ensemblfungi:YLR453C	intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W	psi-mi:rif2_yeast(display_long)|uniprotkb:RIF2(gene name)|psi-mi:RIF2(display_short)|uniprotkb:RAP1-interacting factor 2(gene name synonym)|uniprotkb:YLR453C(locus name)	psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Shi et al. (2013)	imex:IM-21427|pubmed:23746845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8765667|wwpdb:4BJ5|imex:IM-21427-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000004445|refseq:NP_013558.3|ensemblfungi:YLR453C(gene)|ensemblfungi:YLR453C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070187"(shelterin complex)|rcsb pdb:4BJ1|rcsb pdb:4BJ5|rcsb pdb:4BJ6|dip:DIP-4290N	sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938	-	-	crc64:67C4AFB03B3C0713	3d-resolution:3.3A|3d-r-factors:R = 0.18 Rwork = 0.18 Rfree = 0.19|figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/19	2014/10/16	rogid:DKgvGLSUFxdJ8D4kLgAXZiNtimQ559292	rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292	intact-crc:565D3A7054D571C8|rigid:LO8gF45Q/Fm12oU0cWF7h1SSKkA	false	sufficient binding region:2-395	sufficient binding region:672-827	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11938	uniprotkb:P29539	intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W	intact:EBI-2083307|uniprotkb:D6VQS1|uniprotkb:P89507|ensemblfungi:YBR275C	psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym)	psi-mi:rif1_yeast(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:RAP1-interacting factor 1(gene name synonym)|uniprotkb:YBR1743(orf name)|uniprotkb:YBR275C(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Shi et al. (2013)	imex:IM-21427|pubmed:23746845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8765862|wwpdb:4bjt|imex:IM-21427-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938	sgd:S000000479|refseq:NP_009834.4|dip:DIP-801N|mint:P29539|ensemblfungi:YBR275C(gene)|ensemblfungi:YBR275C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0016233"(telomere capping)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:0101018"(negative regulation of mitotic DNA replication initiation from late origin)|interpro:IPR022031|interpro:IPR028566|rcsb pdb:4BJS|rcsb pdb:4BJT|rcsb pdb:5NVR|rcsb pdb:5NW5	-	crc64:67C4AFB03B3C0713	-	3d-resolution:1.6A|3d-r-factors:Rwork = 0.17 Rfree = 0.18|figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/19	2014/10/16	rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292	rogid:zQ0Ljkemo6SMWT8CreVFclqCa7k559292	intact-crc:FCBC8651D722538A|rigid:R/jIMl1s6x9AdMV0i5oDzEOcGs4	false	sufficient binding region:672-827	sufficient binding region:1752-1772	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11938	uniprotkb:P29539	intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W	intact:EBI-2083307|uniprotkb:D6VQS1|uniprotkb:P89507|ensemblfungi:YBR275C	psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym)	psi-mi:rif1_yeast(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:RAP1-interacting factor 1(gene name synonym)|uniprotkb:YBR1743(orf name)|uniprotkb:YBR275C(locus name)	psi-mi:"MI:0018"(two hybrid)	Shi et al. (2013)	imex:IM-21427|pubmed:23746845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8769011|wwpdb:4bjt|imex:IM-21427-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938	sgd:S000000479|refseq:NP_009834.4|dip:DIP-801N|mint:P29539|ensemblfungi:YBR275C(gene)|ensemblfungi:YBR275C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0016233"(telomere capping)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:0101018"(negative regulation of mitotic DNA replication initiation from late origin)|interpro:IPR022031|interpro:IPR028566|rcsb pdb:4BJS|rcsb pdb:4BJT|rcsb pdb:5NVR|rcsb pdb:5NW5	-	crc64:67C4AFB03B3C0713	-	figure legend:Fig 2E/G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/09/19	2014/10/16	rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292	rogid:zQ0Ljkemo6SMWT8CreVFclqCa7k559292	intact-crc:D7049583C271C6C5|rigid:R/jIMl1s6x9AdMV0i5oDzEOcGs4	false	sufficient binding region:672-827|mutation disrupting interaction strength:733-733|mutation disrupting interaction strength:760-760	sufficient binding region:1709-1916|mutation disrupting interaction strength:1760-1760|mutation disrupting interaction strength:1905-1905|mutation decreasing interaction strength:1895-1895|mutation disrupting interaction strength:1762-1762|mutation disrupting interaction strength:1764-1764	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29539	uniprotkb:P29539	intact:EBI-2083307|uniprotkb:D6VQS1|uniprotkb:P89507|ensemblfungi:YBR275C	intact:EBI-2083307|uniprotkb:D6VQS1|uniprotkb:P89507|ensemblfungi:YBR275C	psi-mi:rif1_yeast(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:RAP1-interacting factor 1(gene name synonym)|uniprotkb:YBR1743(orf name)|uniprotkb:YBR275C(locus name)	psi-mi:rif1_yeast(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:RAP1-interacting factor 1(gene name synonym)|uniprotkb:YBR1743(orf name)|uniprotkb:YBR275C(locus name)	psi-mi:"MI:0067"(light scattering)	Shi et al. (2013)	imex:IM-21427|pubmed:23746845	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9006893|imex:IM-21427-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000479|refseq:NP_009834.4|dip:DIP-801N|mint:P29539|ensemblfungi:YBR275C(gene)|ensemblfungi:YBR275C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0016233"(telomere capping)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:0101018"(negative regulation of mitotic DNA replication initiation from late origin)|interpro:IPR022031|interpro:IPR028566|rcsb pdb:4BJS|rcsb pdb:4BJT|rcsb pdb:5NVR|rcsb pdb:5NW5	sgd:S000000479|refseq:NP_009834.4|dip:DIP-801N|mint:P29539|ensemblfungi:YBR275C(gene)|ensemblfungi:YBR275C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0016233"(telomere capping)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0032297"(negative regulation of DNA-dependent DNA replication initiation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:0101018"(negative regulation of mitotic DNA replication initiation from late origin)|interpro:IPR022031|interpro:IPR028566|rcsb pdb:4BJS|rcsb pdb:4BJT|rcsb pdb:5NVR|rcsb pdb:5NW5	-	-	-	figure legend:Supp. Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/09/19	2014/10/16	rogid:zQ0Ljkemo6SMWT8CreVFclqCa7k559292	rogid:zQ0Ljkemo6SMWT8CreVFclqCa7k559292	intact-crc:753DD1ACCB1C8EE6|rigid:fVQQueDuqwpV8muhghgbjNPTLHc	false	mutation decreasing interaction strength:1905-1905|sufficient binding region:1709-1916	mutation decreasing interaction strength:1905-1905|sufficient binding region:1709-1916	4	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)