#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q02410	uniprotkb:Q9NRW1	intact:EBI-368690|uniprotkb:O14914|uniprotkb:O60570|uniprotkb:Q5VYR8|intact:EBI-8840163|intact:EBI-8840293|ensembl:ENSP00000265381	intact:EBI-1760079|uniprotkb:D3DND3|uniprotkb:B2R5Z9|uniprotkb:Q92929|uniprotkb:B7Z337|ensembl:ENSP00000285208|ensembl:ENSP00000437797	psi-mi:apba1_human(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)	psi-mi:rab6b_human(display_long)|uniprotkb:RAB6B(gene name)|psi-mi:RAB6B(display_short)	psi-mi:"MI:0018"(two hybrid)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840166|imex:IM-21673-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005252025.1|refseq:XP_011516919.1|refseq:NP_001154.2|ensembl:ENST00000265381(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030530|interpro:IPR036034|rcsb pdb:1AQC|ensembl:ENSG00000107282(gene)|rcsb pdb:1U37|rcsb pdb:1U38|rcsb pdb:1U39|rcsb pdb:1U3B|rcsb pdb:1X11|rcsb pdb:1X45|rcsb pdb:1Y7N|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|refseq:XP_016870159.1	refseq:XP_011511195.1|refseq:NP_057661.3|ensembl:ENSG00000154917(gene)|ensembl:ENST00000285208(transcript)|ensembl:ENST00000543906(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9NRW1|rcsb pdb:2E9S|rcsb pdb:2FE4|rcsb pdb:2FFQ|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198	-	-	-	figure legend:no figure or table|comment:"A  (prey)  clone was isolated that contained a fragment, which was identified as Mint1 (pP6 Mint1, aa 438–769) by partially sequencing from both ends."|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/10/31	2014/10/16	rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606	rogid:GmhjkLknjr8fxoUBxNx5ak5S/hQ9606	intact-crc:6B50187F866C195E|rigid:r6QFdf8tRP+1cVUgjGcoAkMT21o	false	sufficient binding region:438-769	mutation:72-72	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q02410-2	uniprotkb:Q9NRW1	intact:EBI-9247455	intact:EBI-1760079|uniprotkb:D3DND3|uniprotkb:B2R5Z9|uniprotkb:Q92929|uniprotkb:B7Z337|ensembl:ENSP00000285208|ensembl:ENSP00000437797	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:rab6b_human(display_long)|uniprotkb:RAB6B(gene name)|psi-mi:RAB6B(display_short)	psi-mi:"MI:0018"(two hybrid)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840227|imex:IM-21673-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-368690(isoform-parent)	refseq:XP_011511195.1|refseq:NP_057661.3|ensembl:ENSG00000154917(gene)|ensembl:ENST00000285208(transcript)|ensembl:ENST00000543906(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9NRW1|rcsb pdb:2E9S|rcsb pdb:2FE4|rcsb pdb:2FFQ|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198	intact:EBI-8840307(see-also)	isoform-comment:This isoform interacts with RAB6 GTPases.	-	figure legend:TABLE 1 and 3,4|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/10/31	2014/10/16	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	rogid:GmhjkLknjr8fxoUBxNx5ak5S/hQ9606	intact-crc:6B70AFD0B6AD8A91|rigid:h+QHEfXT2l7Jbv6Dc3ahE8XLFag	false	sufficient binding region:438-603	mutation:72-72|mutation disrupting interaction:27-27	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02410-2	uniprotkb:P20340-1	intact:EBI-9247455	intact:EBI-8851226|ensembl:ENSP00000336850	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:p20340-1(display_long)|uniprotkb:Rab-6a(isoform synonym)|uniprotkb:RAB6A(gene name)|psi-mi:RAB6A(display_short)|uniprotkb:RAB6(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840230|imex:IM-21673-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-368690(isoform-parent)	intact:EBI-1052826(isoform-parent)|ensembl:ENST00000336083(transcript)|ensembl:ENSG00000175582(gene)	intact:EBI-8840304(see-also)	isoform-comment:This isoform interacts with RAB6 GTPases.	-	figure legend:TABLE 1 and 3,4|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/10/31	2014/10/16	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	rogid:VtLF/2T3LuVttzSCftP/mnAxyLk9606	intact-crc:8F0ECB72FBEE7467|rigid:fWH+eh1+S8EIGS4evz6aanIG5GI	false	sufficient binding region:438-603	mutation disrupting interaction:27-27|mutation:72-72	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20340-2	uniprotkb:Q02410-2	intact:EBI-8840191|ensembl:ENSP00000311449	intact:EBI-9247455	psi-mi:p20340-2(display_long)|uniprotkb:Rab-6a'(isoform synonym)|uniprotkb:Rab-6C(isoform synonym)|uniprotkb:Rab6C(isoform synonym)|uniprotkb:RAB6A(gene name)|psi-mi:RAB6A(display_short)|uniprotkb:RAB6(gene name synonym)	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840233|imex:IM-21673-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1052826(isoform-parent)|ensembl:ENSG00000175582(gene)|ensembl:ENST00000310653(transcript)|uniprotkb:P20340-2(isoform-parent)	intact:EBI-368690(isoform-parent)	-	-	isoform-comment:This isoform interacts with RAB6 GTPases.	figure legend:TABLE 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/10/31	2014/10/16	rogid:0ivdHUzOB/MizvmG6/QQec0MqzQ9606	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	intact-crc:95678F42C8E76267|rigid:+LUY7gFvMPTv4HxlV6H6y6Ocfyc	false	mutation:72-72	sufficient binding region:438-826	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B2RUJ5	uniprotkb:P61294	intact:EBI-8840254|uniprotkb:Q3UH49|uniprotkb:Q8BMF2|ensembl:ENSMUSP00000025830	intact:EBI-529766|ensembl:ENSMUSP00000035155	psi-mi:apba1_mouse(display_long)|uniprotkb:Apba1(gene name)|psi-mi:Apba1(display_short)|uniprotkb:Mint1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:mLin-10(gene name synonym)	psi-mi:rab6b_mouse(display_long)|uniprotkb:Rab6b(gene name)|psi-mi:Rab6b(display_short)|uniprotkb:D9Bwg0185e(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840212|imex:IM-21673-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_796008.2|refseq:XP_006527202.1|refseq:XP_006527203.1|ensembl:ENSMUSG00000024897(gene)|ensembl:ENSMUST00000025830(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030530|interpro:IPR036034|rcsb pdb:6LNM|reactome:R-MMU-212676	refseq:NP_776142.1|ensembl:ENSMUSG00000032549(gene)|ensembl:ENSMUST00000035155(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61294|reactome:R-MMU-6811436|reactome:R-MMU-6811440|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198	go:"GO:0005794"(Golgi apparatus)	-	-	figure legend:Fig 1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-neuron)|taxid:10090(Mus musculus neuronal cell)	-	2013/10/31	2014/10/16	rogid:yiX/e1Bf0TWarwbKXyhDvvm1rG810090	rogid:GmhjkLknjr8fxoUBxNx5ak5S/hQ10090	intact-crc:05A79297579F3F8C|rigid:JU5y3ZxrGRPPhM2RFShbIIddqms	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q02410-2	uniprotkb:P05067-4	intact:EBI-9247455	intact:EBI-302641|ensembl:ENSP00000345463|intact:EBI-8513344|intact:MINT-150885|intact:EBI-8513450|intact:EBI-8513789|intact:EBI-7458081|intact:EBI-7458225|intact:EBI-8513738|intact:EBI-8513677|intact:EBI-8513407|intact:EBI-7457926	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:p05067-4(display_long)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:PreA4 695(isoform synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8841390|imex:IM-21673-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-368690(isoform-parent)	intact:EBI-77613(a4_human)|ensembl:ENSG00000142192(gene)|ensembl:ENST00000348990(transcript)	go:"GO:0031982"(vesicle)|go:"GO:0005794"(Golgi apparatus)	isoform-comment:This isoform interacts with RAB6 GTPases.	isoform-comment:A major isoform.	figure legend:9A|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/31	2014/10/16	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	rogid:g3lIuSzu8RGEONgITBEVFyMpfqk9606	intact-crc:0923BE8659D44F87|rigid:k+reiaf6Zr0gE1ASXCbw100ppUI	false	enhanced green fluorescent protein tag:?-?	red fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q02410-2	uniprotkb:P35279	intact:EBI-9247455	intact:EBI-444674|uniprotkb:Q542M6|uniprotkb:Q8R2Z7|uniprotkb:Q8VEE5|uniprotkb:Q9JJD4|ensembl:ENSMUSP00000032946	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:rab6a_mouse(display_long)|uniprotkb:Rab6a(gene name)|psi-mi:Rab6a(display_short)|uniprotkb:Rab6(gene name synonym)|uniprotkb:MNCb-1660(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8841337|imex:IM-21673-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-368690(isoform-parent)	refseq:NP_001157135.1|refseq:NP_077249.1|ensembl:ENSMUSG00000030704(gene)|ensembl:ENSMUST00000032946(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0018125"(peptidyl-cysteine methylation)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0051117"(ATPase binding)|go:"GO:0070381"(endosome to plasma membrane transport vesicle)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P35279|reactome:R-MMU-6798695|reactome:R-MMU-6811436|reactome:R-MMU-6811440|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198|dip:DIP-120N	go:"GO:0005794"(Golgi apparatus)	isoform-comment:This isoform interacts with RAB6 GTPases.	-	figure legend:Fig 8A|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells)	-	2013/10/31	2014/10/16	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	rogid:dvs8ZexwDDVZ3QFifBZ+id2D0+k10090	intact-crc:513074A2FC7BB248|rigid:06pnPhTLB67eGu0oOgykzNBwUtc	false	enhanced green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P05067-4	uniprotkb:Q02410-2	intact:EBI-302641|ensembl:ENSP00000345463|intact:EBI-8513344|intact:MINT-150885|intact:EBI-8513450|intact:EBI-8513789|intact:EBI-7458081|intact:EBI-7458225|intact:EBI-8513738|intact:EBI-8513677|intact:EBI-8513407|intact:EBI-7457926	intact:EBI-9247455	psi-mi:p05067-4(display_long)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:PreA4 695(isoform synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8841365|imex:IM-21673-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-77613(a4_human)|ensembl:ENSG00000142192(gene)|ensembl:ENST00000348990(transcript)	intact:EBI-368690(isoform-parent)	go:"GO:0005794"(Golgi apparatus)|go:"GO:0031982"(vesicle)	isoform-comment:A major isoform.	isoform-comment:This isoform interacts with RAB6 GTPases.	figure legend:9B|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-neuron)|taxid:10090(Mus musculus neuronal cell)	-	2013/10/31	2014/10/16	rogid:g3lIuSzu8RGEONgITBEVFyMpfqk9606	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	intact-crc:ADC0BF392135C256|rigid:k+reiaf6Zr0gE1ASXCbw100ppUI	false	red fluorescent protein tag:c-c	enhanced green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9NRW1	uniprotkb:P05067-4	intact:EBI-1760079|uniprotkb:D3DND3|uniprotkb:B2R5Z9|uniprotkb:Q92929|uniprotkb:B7Z337|ensembl:ENSP00000285208|ensembl:ENSP00000437797	intact:EBI-302641|ensembl:ENSP00000345463|intact:EBI-8513344|intact:MINT-150885|intact:EBI-8513450|intact:EBI-8513789|intact:EBI-7458081|intact:EBI-7458225|intact:EBI-8513738|intact:EBI-8513677|intact:EBI-8513407|intact:EBI-7457926	psi-mi:rab6b_human(display_long)|uniprotkb:RAB6B(gene name)|psi-mi:RAB6B(display_short)	psi-mi:p05067-4(display_long)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:PreA4 695(isoform synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8841410|imex:IM-21673-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511195.1|refseq:NP_057661.3|ensembl:ENSG00000154917(gene)|ensembl:ENST00000285208(transcript)|ensembl:ENST00000543906(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9NRW1|rcsb pdb:2E9S|rcsb pdb:2FE4|rcsb pdb:2FFQ|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198	intact:EBI-77613(a4_human)|ensembl:ENSG00000142192(gene)|ensembl:ENST00000348990(transcript)	go:"GO:0005794"(Golgi apparatus)	-	isoform-comment:A major isoform.	figure legend:9C and Movie S1|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cv-1)|taxid:9534(Monkey African Green kidney fibroblast)	-	2013/10/31	2014/10/16	rogid:GmhjkLknjr8fxoUBxNx5ak5S/hQ9606	rogid:g3lIuSzu8RGEONgITBEVFyMpfqk9606	intact-crc:C582359A0A7DC1F4|rigid:p4DeVWpUY+9tjY7yEAonZmmZxeE	false	mutation:72-72|red fluorescent protein tag:?-?	enhanced green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q02410-2	uniprotkb:Q9NRW1	intact:EBI-9247455	intact:EBI-1760079|uniprotkb:D3DND3|uniprotkb:B2R5Z9|uniprotkb:Q92929|uniprotkb:B7Z337|ensembl:ENSP00000285208|ensembl:ENSP00000437797	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:rab6b_human(display_long)|uniprotkb:RAB6B(gene name)|psi-mi:RAB6B(display_short)	psi-mi:"MI:0096"(pull down)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840370|imex:IM-21673-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-368690(isoform-parent)	refseq:XP_011511195.1|refseq:NP_057661.3|ensembl:ENSG00000154917(gene)|ensembl:ENST00000285208(transcript)|ensembl:ENST00000543906(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9NRW1|rcsb pdb:2E9S|rcsb pdb:2FE4|rcsb pdb:2FFQ|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198	intact:EBI-8840419(see-also)	isoform-comment:This isoform interacts with RAB6 GTPases.	-	figure legend:Fig 2A|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	rogid:GmhjkLknjr8fxoUBxNx5ak5S/hQ9606	intact-crc:31C68ABDED3351D1|rigid:h+QHEfXT2l7Jbv6Dc3ahE8XLFag	false	glutathione s tranferase tag:n-n|sufficient binding region:438-603(IPR006020)	mutation:72-72|mutation disrupting interaction:27-27|green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P20340-1	uniprotkb:Q02410-2	intact:EBI-8851226|ensembl:ENSP00000336850	intact:EBI-9247455	psi-mi:p20340-1(display_long)|uniprotkb:Rab-6a(isoform synonym)|uniprotkb:RAB6A(gene name)|psi-mi:RAB6A(display_short)|uniprotkb:RAB6(gene name synonym)	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840382|imex:IM-21673-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1052826(isoform-parent)|ensembl:ENST00000336083(transcript)|ensembl:ENSG00000175582(gene)	intact:EBI-368690(isoform-parent)	intact:EBI-8840423(see-also)	-	isoform-comment:This isoform interacts with RAB6 GTPases.	figure legend:Fig 2A|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:VtLF/2T3LuVttzSCftP/mnAxyLk9606	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	intact-crc:732A855AE03DF032|rigid:fWH+eh1+S8EIGS4evz6aanIG5GI	false	cyan fluorescent protein tag:c-c|mutation:72-72|mutation disrupting interaction:27-27	sufficient binding region:438-603(IPR006020)|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q02410-2	uniprotkb:P05067-4	intact:EBI-9247455	intact:EBI-302641|ensembl:ENSP00000345463|intact:EBI-8513344|intact:MINT-150885|intact:EBI-8513450|intact:EBI-8513789|intact:EBI-7458081|intact:EBI-7458225|intact:EBI-8513738|intact:EBI-8513677|intact:EBI-8513407|intact:EBI-7457926	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:p05067-4(display_long)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:PreA4 695(isoform synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8841307|imex:IM-21673-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-368690(isoform-parent)	intact:EBI-77613(a4_human)|ensembl:ENSG00000142192(gene)|ensembl:ENST00000348990(transcript)	intact:EBI-8840423(see-also)	isoform-comment:This isoform interacts with RAB6 GTPases.	isoform-comment:A major isoform.	figure legend:Fig 7|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	rogid:g3lIuSzu8RGEONgITBEVFyMpfqk9606	intact-crc:27CC9D50F02DEFAA|rigid:k+reiaf6Zr0gE1ASXCbw100ppUI	false	glutathione s tranferase tag:n-n|sufficient binding region:438-603(IPR006020)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NRW1	uniprotkb:Q02410-2	intact:EBI-1760079|uniprotkb:D3DND3|uniprotkb:B2R5Z9|uniprotkb:Q92929|uniprotkb:B7Z337|ensembl:ENSP00000285208|ensembl:ENSP00000437797	intact:EBI-9247455	psi-mi:rab6b_human(display_long)|uniprotkb:RAB6B(gene name)|psi-mi:RAB6B(display_short)	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840473|imex:IM-21673-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511195.1|refseq:NP_057661.3|ensembl:ENSG00000154917(gene)|ensembl:ENST00000285208(transcript)|ensembl:ENST00000543906(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9NRW1|rcsb pdb:2E9S|rcsb pdb:2FE4|rcsb pdb:2FFQ|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198	intact:EBI-368690(isoform-parent)	intact:EBI-8840419(see-also)	-	isoform-comment:This isoform interacts with RAB6 GTPases.	figure legend:Fig 2B|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:GmhjkLknjr8fxoUBxNx5ak5S/hQ9606	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	intact-crc:1B2D0FDCBA1074CB|rigid:h+QHEfXT2l7Jbv6Dc3ahE8XLFag	false	mutation disrupting interaction:27-27|glutathione s tranferase tag:?-?|mutation:72-72	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q02410-2	uniprotkb:P20340-1	intact:EBI-9247455	intact:EBI-8851226|ensembl:ENSP00000336850	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:p20340-1(display_long)|uniprotkb:Rab-6a(isoform synonym)|uniprotkb:RAB6A(gene name)|psi-mi:RAB6A(display_short)|uniprotkb:RAB6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840469|imex:IM-21673-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-368690(isoform-parent)	intact:EBI-1052826(isoform-parent)|ensembl:ENST00000336083(transcript)|ensembl:ENSG00000175582(gene)	intact:EBI-8840423(see-also)	isoform-comment:This isoform interacts with RAB6 GTPases.	-	figure legend:Fig 2B|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	rogid:VtLF/2T3LuVttzSCftP/mnAxyLk9606	intact-crc:1E17049ADA7C215A|rigid:fWH+eh1+S8EIGS4evz6aanIG5GI	false	-	glutathione s tranferase tag:?-?|mutation:72-72|mutation disrupting interaction:27-27	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P20340-1	uniprotkb:B2RUJ5	intact:EBI-8851226|ensembl:ENSP00000336850	intact:EBI-8840254|uniprotkb:Q3UH49|uniprotkb:Q8BMF2|ensembl:ENSMUSP00000025830	psi-mi:p20340-1(display_long)|uniprotkb:Rab-6a(isoform synonym)|uniprotkb:RAB6A(gene name)|psi-mi:RAB6A(display_short)|uniprotkb:RAB6(gene name synonym)	psi-mi:apba1_mouse(display_long)|uniprotkb:Apba1(gene name)|psi-mi:Apba1(display_short)|uniprotkb:Mint1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:mLin-10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840609|imex:IM-21673-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1052826(isoform-parent)|ensembl:ENST00000336083(transcript)|ensembl:ENSG00000175582(gene)	refseq:NP_796008.2|refseq:XP_006527202.1|refseq:XP_006527203.1|ensembl:ENSMUSG00000024897(gene)|ensembl:ENSMUST00000025830(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030530|interpro:IPR036034|rcsb pdb:6LNM|reactome:R-MMU-212676	intact:EBI-8840423(see-also)	-	-	figure legend:Fig 5|comment:The antibody used can detect both isoforms of MINT1 but the authors state that  as only Mint1 826 but not Mint1 can bind to Rab6,  this pulldown experiment indicates that  the Mint1 826 protein is present in mouse brain tissue and that this endogenous Mint1 826 can interact with Rab6.|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/31	2014/10/16	rogid:VtLF/2T3LuVttzSCftP/mnAxyLk9606	rogid:yiX/e1Bf0TWarwbKXyhDvvm1rG810090	intact-crc:25D47CD3B6E248E2|rigid:Wo4l+gOY8U/qRnn2kB9nq3heDUI	false	mutation:72-72|mutation disrupting interaction:27-27|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NRW1	uniprotkb:Q02410-2	intact:EBI-1760079|uniprotkb:D3DND3|uniprotkb:B2R5Z9|uniprotkb:Q92929|uniprotkb:B7Z337|ensembl:ENSP00000285208|ensembl:ENSP00000437797	intact:EBI-9247455	psi-mi:rab6b_human(display_long)|uniprotkb:RAB6B(gene name)|psi-mi:RAB6B(display_short)	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840541|imex:IM-21673-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011511195.1|refseq:NP_057661.3|ensembl:ENSG00000154917(gene)|ensembl:ENST00000285208(transcript)|ensembl:ENST00000543906(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9NRW1|rcsb pdb:2E9S|rcsb pdb:2FE4|rcsb pdb:2FFQ|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198	intact:EBI-368690(isoform-parent)	intact:EBI-8840571(see-also)	-	isoform-comment:This isoform interacts with RAB6 GTPases.	figure legend:Fig 3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/31	2014/10/16	rogid:GmhjkLknjr8fxoUBxNx5ak5S/hQ9606	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	intact-crc:4DD496208845924A|rigid:h+QHEfXT2l7Jbv6Dc3ahE8XLFag	false	mutation:72-72|cyan fluorescent protein tag:c-c	sufficient binding region:438-603(IPR006020)|enhanced yellow fluorescent protein tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P20340-1	uniprotkb:Q02410-2	intact:EBI-8851226|ensembl:ENSP00000336850	intact:EBI-9247455	psi-mi:p20340-1(display_long)|uniprotkb:Rab-6a(isoform synonym)|uniprotkb:RAB6A(gene name)|psi-mi:RAB6A(display_short)|uniprotkb:RAB6(gene name synonym)	psi-mi:q02410-2(display_long)|uniprotkb:Mint1_826(isoform synonym)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Thyrock et al. (2013)	pubmed:23737971|imex:IM-21673	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8840525|imex:IM-21673-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1052826(isoform-parent)|ensembl:ENST00000336083(transcript)|ensembl:ENSG00000175582(gene)	intact:EBI-368690(isoform-parent)	intact:EBI-8840574(see-also)	-	isoform-comment:This isoform interacts with RAB6 GTPases.	figure legend:Fig 3|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/31	2014/10/16	rogid:VtLF/2T3LuVttzSCftP/mnAxyLk9606	rogid:XtzqNQD+R5IIrDSwidJFDztVQ2s9606	intact-crc:672695B303CBE691|rigid:fWH+eh1+S8EIGS4evz6aanIG5GI	false	mutation:72-72|cyan fluorescent protein tag:c-c	sufficient binding region:438-603(IPR006020)|enhanced yellow fluorescent protein tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)