#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q08117	uniprotkb:O75360	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|uniprotkb:B2RBL0|uniprotkb:Q14CJ1|ensembl:ENSP00000317537	intact:EBI-9027467|ensembl:ENSP00000311290	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:prop1_human(display_long)|uniprotkb:PROP1(gene name)|psi-mi:PROP1(display_short)|uniprotkb:Pituitary-specific homeodomain factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sugiyama et al. (2013)	imex:IM-21837|pubmed:23732115	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-9027465|imex:IM-21837-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001121.2|refseq:NP_945320.1|refseq:NP_945321.1|ensembl:ENSG00000104964(gene)|ensembl:ENST00000327141(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|go:"GO:0032091"(negative regulation of protein binding)	refseq:NP_006252.3|ensembl:ENSG00000175325(gene)|ensembl:ENST00000308304(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021983"(pituitary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042412	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/12/05	2014/10/16	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:SzGxUvE6Zjw2HFU5idYlhBj3neM9606	intact-crc:4149392B5E9826B0|rigid:RRgVyjqYlWFEPKZgSGAHfe9ZyPA	false	-	sufficient binding region:128-226	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75360	uniprotkb:P11142	intact:EBI-9027467|ensembl:ENSP00000311290	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:prop1_human(display_long)|uniprotkb:PROP1(gene name)|psi-mi:PROP1(display_short)|uniprotkb:Pituitary-specific homeodomain factor(gene name synonym)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sugiyama et al. (2013)	imex:IM-21837|pubmed:23732115	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-9030944|imex:IM-21837-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006252.3|ensembl:ENSG00000175325(gene)|ensembl:ENST00000308304(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021983"(pituitary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042412	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/12/05	2014/10/16	rogid:SzGxUvE6Zjw2HFU5idYlhBj3neM9606	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	intact-crc:29C5DD3CFE00D3C5|rigid:1fq8aQBLrz6/ifrpawFZm+TSa94	false	sufficient binding region:128-226	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q719H9	uniprotkb:O75360	intact:EBI-9027502|uniprotkb:A8K1F5|ensembl:ENSP00000314831|ensembl:ENSP00000384367|ensembl:ENSP00000408405|ensembl:ENSP00000464170	intact:EBI-9027467|ensembl:ENSP00000311290	psi-mi:kctd1_human(display_long)|uniprotkb:KCTD1(gene name)|psi-mi:KCTD1(display_short)|uniprotkb:C18orf5(gene name synonym)|uniprotkb:Potassium channel tetramerization domain-containing protein 1(gene name synonym)	psi-mi:prop1_human(display_long)|uniprotkb:PROP1(gene name)|psi-mi:PROP1(display_short)|uniprotkb:Pituitary-specific homeodomain factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sugiyama et al. (2013)	imex:IM-21837|pubmed:23732115	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-9030745|imex:IM-21837-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016881197.1|refseq:NP_001129677.1|refseq:NP_001136202.1|refseq:NP_001245150.1|refseq:NP_945342.1|ensembl:ENSG00000134504(gene)|ensembl:ENST00000317932(transcript)|ensembl:ENST00000408011(transcript)|ensembl:ENST00000417602(transcript)|ensembl:ENST00000579973(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q719H9|rcsb pdb:5BXB|rcsb pdb:5BXD|rcsb pdb:6S4L|reactome:R-HSA-8866904	refseq:NP_006252.3|ensembl:ENSG00000175325(gene)|ensembl:ENST00000308304(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021983"(pituitary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042412	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/12/05	2014/10/16	rogid:mv4g8/+TuoNkCitdTYpsxJH52I09606	rogid:SzGxUvE6Zjw2HFU5idYlhBj3neM9606	intact-crc:A1C685ABCDB532C1|rigid:0wGIqjJ4LQnWlVD0xJ6TH7/vNzA	false	-	sufficient binding region:128-226	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IXL6	uniprotkb:O75360	intact:EBI-7147442|uniprotkb:L8B5W8|ensembl:ENSP00000322323|ensembl:ENSP00000499851|uniprotkb:Q7Z4I0|uniprotkb:Q5I0W9|intact:MINT-6940404|uniprotkb:A4D2Q5|uniprotkb:Q9NPT2	intact:EBI-9027467|ensembl:ENSP00000311290	psi-mi:fa20c_human(display_long)|uniprotkb:Dentin matrix protein 4(gene name synonym)|uniprotkb:Golgi-enriched fraction casein kinase(gene name synonym)|uniprotkb:FAM20C(gene name)|psi-mi:FAM20C(display_short)|uniprotkb:DMP4(gene name synonym)|uniprotkb:Golgi casein kinase(gene name synonym)	psi-mi:prop1_human(display_long)|uniprotkb:PROP1(gene name)|psi-mi:PROP1(display_short)|uniprotkb:Pituitary-specific homeodomain factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sugiyama et al. (2013)	imex:IM-21837|pubmed:23732115	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-9030977|imex:IM-21837-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000177706(gene)|ensembl:ENSG00000288499(gene)|ensembl:ENST00000313766(transcript)|ensembl:ENST00000672066(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016773"(phosphotransferase activity, alcohol group as acceptor)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070166"(enamel mineralization)|go:"GO:0071895"(odontoblast differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR009581(Protein of unknown function DUF1193)|interpro:IPR024869|rcsb pdb:5YH3|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_064608.2	refseq:NP_006252.3|ensembl:ENSG00000175325(gene)|ensembl:ENST00000308304(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021983"(pituitary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042412	-	function:Calcium-binding protein which may play a role in dentin mineralization|function:"Defects in FAM20C are the cause of Raine syndrome (RNS) [MIM:259775]. RNS is an autosomal recessive osteosclerotic bone dysplasia with neonatal lethal outcome. Clinical features include generalized osteosclerosis, craniofacial dysplasia and microcephaly"|comment:mint|comment:homomint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/12/05	2014/10/16	rogid:hro7o7c0vsYAzpP2iQblks6dvfs9606	rogid:SzGxUvE6Zjw2HFU5idYlhBj3neM9606	intact-crc:F757FFFCC38901FD|rigid:MXi4spuK5XNoEtDr7kDuwAMFz6U	false	-	sufficient binding region:128-226	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75360	uniprotkb:Q12805	intact:EBI-9027467|ensembl:ENSP00000311290	intact:EBI-536772|uniprotkb:Q541U7|uniprotkb:A8K3I4|uniprotkb:D6W5D2|ensembl:ENSP00000347596|ensembl:ENSP00000378058|uniprotkb:B4DW75	psi-mi:prop1_human(display_long)|uniprotkb:PROP1(gene name)|psi-mi:PROP1(display_short)|uniprotkb:Pituitary-specific homeodomain factor(gene name synonym)	psi-mi:fbln3_human(display_long)|uniprotkb:Fibulin-3(gene name synonym)|uniprotkb:Fibrillin-like protein(gene name synonym)|uniprotkb:Extracellular protein S1-5(gene name synonym)|uniprotkb:EFEMP1(gene name)|psi-mi:EFEMP1(display_short)|uniprotkb:FBLN3(gene name synonym)|uniprotkb:FBNL(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sugiyama et al. (2013)	imex:IM-21837|pubmed:23732115	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-9030755|imex:IM-21837-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006252.3|ensembl:ENSG00000175325(gene)|ensembl:ENST00000308304(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021983"(pituitary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042412	ensembl:ENSG00000115380(gene)|ensembl:ENST00000355426(transcript)|ensembl:ENST00000394555(transcript)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0008083"(growth factor activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0043010"(camera-type eye development)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR032973|mint:Q12805|reactome:R-HSA-2129379|refseq:NP_001034437.1|refseq:NP_001034438.1	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/12/05	2014/10/16	rogid:SzGxUvE6Zjw2HFU5idYlhBj3neM9606	rogid:V32dS+EEp5Syu3A6lQJal0fg6UM9606	intact-crc:0774E91DBAED6FF6|rigid:N/kRKx1SVTaA9Sth1NdeGPBtAAM	false	sufficient binding region:128-226	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P49418	uniprotkb:O75360	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	intact:EBI-9027467|ensembl:ENSP00000311290	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:prop1_human(display_long)|uniprotkb:PROP1(gene name)|psi-mi:PROP1(display_short)|uniprotkb:Pituitary-specific homeodomain factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sugiyama et al. (2013)	imex:IM-21837|pubmed:23732115	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-9030970|imex:IM-21837-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N	refseq:NP_006252.3|ensembl:ENSG00000175325(gene)|ensembl:ENST00000308304(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021983"(pituitary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042412	-	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/12/05	2014/10/16	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	rogid:SzGxUvE6Zjw2HFU5idYlhBj3neM9606	intact-crc:85F824B39C033049|rigid:G2vuEEQsbaTQcgE8Hi28+vpC/bc	false	-	sufficient binding region:128-226	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54259	uniprotkb:O75360	intact:EBI-945980|uniprotkb:Q99495|uniprotkb:Q99621|uniprotkb:Q9UEK7|ensembl:ENSP00000349076|ensembl:ENSP00000379915	intact:EBI-9027467|ensembl:ENSP00000311290	psi-mi:atn1_human(display_long)|uniprotkb:ATN1(gene name)|psi-mi:ATN1(display_short)|uniprotkb:DRPLA(gene name synonym)|uniprotkb:Dentatorubral-pallidoluysian atrophy protein(gene name synonym)|uniprotkb:D12S755E(gene name synonym)	psi-mi:prop1_human(display_long)|uniprotkb:PROP1(gene name)|psi-mi:PROP1(display_short)|uniprotkb:Pituitary-specific homeodomain factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sugiyama et al. (2013)	imex:IM-21837|pubmed:23732115	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-9030447|imex:IM-21837-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007027.1|refseq:NP_001931.2|ensembl:ENSP00000349076|ensembl:ENSP00000379915|dip:DIP-29423N|ensembl:ENSG00000111676(gene)|ensembl:ENST00000356654(transcript)|ensembl:ENST00000396684(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR002951(Atrophin)|interpro:IPR017993|mint:P54259|reactome:R-HSA-8943724	refseq:NP_006252.3|ensembl:ENSG00000175325(gene)|ensembl:ENST00000308304(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021983"(pituitary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042412	-	crc64:B47603486C672637	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/12/05	2014/10/16	rogid:SX8MuZ4aW8/PJmQl4HqY+NOSxbI9606	rogid:SzGxUvE6Zjw2HFU5idYlhBj3neM9606	intact-crc:3652DFDC6D8F4299|rigid:qmQMP72UN1+Fe+3zOa3QjcWi+wg	false	-	sufficient binding region:128-226	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12860	uniprotkb:O75360	intact:EBI-5564336|uniprotkb:A8K0H9|uniprotkb:A8K0Y3|uniprotkb:Q12861|uniprotkb:Q14030|uniprotkb:Q7M4P0|uniprotkb:Q8N466|ensembl:ENSP00000325660|ensembl:ENSP00000447006	intact:EBI-9027467|ensembl:ENSP00000311290	psi-mi:cntn1_human(display_long)|uniprotkb:CNTN1(gene name)|psi-mi:CNTN1(display_short)|uniprotkb:Glycoprotein gp135(gene name synonym)|uniprotkb:Neural cell surface protein F3(gene name synonym)	psi-mi:prop1_human(display_long)|uniprotkb:PROP1(gene name)|psi-mi:PROP1(display_short)|uniprotkb:Pituitary-specific homeodomain factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sugiyama et al. (2013)	imex:IM-21837|pubmed:23732115	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-9030965|imex:IM-21837-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011536228.1|refseq:XP_011536229.1|refseq:NP_001242992.1|refseq:NP_001242993.1|refseq:NP_001834.2|refseq:NP_778203.1|refseq:XP_005268708.1|refseq:XP_006719304.1|refseq:XP_016874314.1|refseq:XP_016874315.1|refseq:XP_016874316.1|dip:DIP-59714N|ensembl:ENSG00000018236(gene)|ensembl:ENST00000347616(transcript)|ensembl:ENST00000551295(transcript)|go:"GO:0007155"(cell adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0045121"(membrane raft)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099025"(anchored component of postsynaptic membrane)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR036992|rcsb pdb:3S97|reactome:R-HSA-2122948|reactome:R-HSA-2979096|reactome:R-HSA-373760|reactome:R-HSA-447043|rcsb pdb:2EE2	refseq:NP_006252.3|ensembl:ENSG00000175325(gene)|ensembl:ENST00000308304(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021983"(pituitary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042412	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/12/05	2014/10/16	rogid:wkqpI3hRQ1Y/Q6JeasMbZYYIWWY9606	rogid:SzGxUvE6Zjw2HFU5idYlhBj3neM9606	intact-crc:2354419FE46C0C93|rigid:Nae7brXYWnnN2hk5yZiFKC+ouhI	false	-	sufficient binding region:128-226	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBB6	uniprotkb:O75360	intact:EBI-1053490|uniprotkb:Q9UBY2|uniprotkb:Q9Y4A6|uniprotkb:Q9Y4D9|uniprotkb:D3DPR9|ensembl:ENSP00000348394|ensembl:ENSP00000362340	intact:EBI-9027467|ensembl:ENSP00000311290	psi-mi:ncdn_human(display_long)|uniprotkb:KIAA0607(gene name synonym)|uniprotkb:NCDN(gene name)|psi-mi:NCDN(display_short)	psi-mi:prop1_human(display_long)|uniprotkb:PROP1(gene name)|psi-mi:PROP1(display_short)|uniprotkb:Pituitary-specific homeodomain factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sugiyama et al. (2013)	imex:IM-21837|pubmed:23732115	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-9030987|imex:IM-21837-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014839.1|refseq:NP_001014841.1|refseq:NP_055099.1|ensembl:ENSG00000020129(gene)|ensembl:ENST00000356090(transcript)|ensembl:ENST00000373243(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045453"(bone resorption)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0098794"(postsynapse)|interpro:IPR008709(Neurochondrin)|interpro:IPR016024(Armadillo-type fold)	refseq:NP_006252.3|ensembl:ENSG00000175325(gene)|ensembl:ENST00000308304(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021983"(pituitary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042412	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/12/05	2014/10/16	rogid:P9HYo2+wb1TUYItUmaq5tEmjFwc9606	rogid:SzGxUvE6Zjw2HFU5idYlhBj3neM9606	intact-crc:4E2E982D4F3D7E8A|rigid:E6tGfiXlc8e/xATSTvnn4y8vxGo	false	-	sufficient binding region:128-226	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q08117	uniprotkb:O75360	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|uniprotkb:B2RBL0|uniprotkb:Q14CJ1|ensembl:ENSP00000317537	intact:EBI-9027467|ensembl:ENSP00000311290	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:prop1_human(display_long)|uniprotkb:PROP1(gene name)|psi-mi:PROP1(display_short)|uniprotkb:Pituitary-specific homeodomain factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sugiyama et al. (2013)	imex:IM-21837|pubmed:23732115	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-9027578|imex:IM-21837-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001121.2|refseq:NP_945320.1|refseq:NP_945321.1|ensembl:ENSG00000104964(gene)|ensembl:ENST00000327141(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|go:"GO:0032091"(negative regulation of protein binding)	refseq:NP_006252.3|ensembl:ENSG00000175325(gene)|ensembl:ENST00000308304(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021983"(pituitary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042412	-	-	-	figure legend:Fig3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2013/12/05	2014/10/16	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:SzGxUvE6Zjw2HFU5idYlhBj3neM9606	intact-crc:9783F045FAA0ECE6|rigid:RRgVyjqYlWFEPKZgSGAHfe9ZyPA	false	his tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q08117	uniprotkb:O75360	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|uniprotkb:B2RBL0|uniprotkb:Q14CJ1|ensembl:ENSP00000317537	intact:EBI-9027467|ensembl:ENSP00000311290	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:prop1_human(display_long)|uniprotkb:PROP1(gene name)|psi-mi:PROP1(display_short)|uniprotkb:Pituitary-specific homeodomain factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sugiyama et al. (2013)	imex:IM-21837|pubmed:23732115	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-9027594|imex:IM-21837-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001121.2|refseq:NP_945320.1|refseq:NP_945321.1|ensembl:ENSG00000104964(gene)|ensembl:ENST00000327141(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|go:"GO:0032091"(negative regulation of protein binding)	refseq:NP_006252.3|ensembl:ENSG00000175325(gene)|ensembl:ENST00000308304(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021983"(pituitary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042412	-	-	-	figure legend:Fig4, Fig5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-gh3)|taxid:10116(Rat pituitary tumor GH3 cells)	-	2013/12/05	2014/10/16	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:SzGxUvE6Zjw2HFU5idYlhBj3neM9606	intact-crc:ABD24F438A59B023|rigid:RRgVyjqYlWFEPKZgSGAHfe9ZyPA	false	sufficient binding region:1-131(IPR005617)	sufficient binding region:128-226	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08117	uniprotkb:O75360	intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|uniprotkb:B2RBL0|uniprotkb:Q14CJ1|ensembl:ENSP00000317537	intact:EBI-9027467|ensembl:ENSP00000311290	psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym)	psi-mi:prop1_human(display_long)|uniprotkb:PROP1(gene name)|psi-mi:PROP1(display_short)|uniprotkb:Pituitary-specific homeodomain factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sugiyama et al. (2013)	imex:IM-21837|pubmed:23732115	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1262"(I2D)	intact:EBI-9027612|imex:IM-21837-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001121.2|refseq:NP_945320.1|refseq:NP_945321.1|ensembl:ENSG00000104964(gene)|ensembl:ENST00000327141(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|go:"GO:0032091"(negative regulation of protein binding)	refseq:NP_006252.3|ensembl:ENSG00000175325(gene)|ensembl:ENST00000308304(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021983"(pituitary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR042412	-	-	-	figure legend:Fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-gh3)|taxid:10116(Rat pituitary tumor GH3 cells)	-	2013/12/05	2014/10/16	rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606	rogid:SzGxUvE6Zjw2HFU5idYlhBj3neM9606	intact-crc:D90BF36E810F574A|rigid:RRgVyjqYlWFEPKZgSGAHfe9ZyPA	false	sufficient binding region:54-133	sufficient binding region:128-226	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)