#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P77302 uniprotkb:P33358 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 intact:EBI-1127668|uniprotkb:Q2MAV3|ensemblbacteria:AAC75188|ensemblbacteria:BAE76603 psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:mlra_ecoli(display_long)|uniprotkb:yehV(gene name synonym)|uniprotkb:MerR-like regulator A(gene name synonym)|uniprotkb:mlrA(gene name)|psi-mi:mlrA(display_short)|uniprotkb:b2127(locus name)|uniprotkb:JW2115(locus name) psi-mi:"MI:0018"(two hybrid) Lindenberg et al. (2013) pubmed:23708798|imex:IM-22038 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9096410|imex:IM-22038-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N refseq:NP_416631.1|interpro:IPR009061(Putative DNA binding)|interpro:IPR000551(Bacterial regulatory protein, MerR)|refseq:WP_001240401.1|ensemblbacteria:b2127(gene)|ensemblbacteria:BAE76603(gene)|ensemblbacteria:BAE76603(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|ensemblbacteria:AAC75188(transcript)|mint:P33358 - - - figure legend:f3a|comment:"Full‐size YdaM did hardly show any indication of interacting with MlrA, nor with the two isolated MlrA domains. However, the isolated YdaM domains showed some interaction with full‐size MlrA. Strikingly, the YdaM‐GGDEF domain alone exhibited strong interaction with MlrA‐CTD, that is, the c‐di‐GMP producing domain of YdaM can make a direct contact with the putative ligand‐binding domain of MlrA. This interaction of MlrA‐CTD was clearly not observed with the full‐size YdaM protein, which means that the presence of the YdaM‐NTD can inhibit a therefore conditional interaction between the YdaM‐GGDEF domain and MlrA‐CTD. Moreover, this interaction was specific, because MlrA‐CTD did not interact with the GGDEF domains of YciR, YegE or YaiC (Figure 3A, lower right panel)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2013/10/21 2014/10/16 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 rogid:gzJgKnruazPYG9CIb46TIMYA9pg83333 intact-crc:0A3CF0CC7EFB18E2|rigid:VcIiYYvkxI2xa7ISIm0HCjMKKm8 false fusion protein:?-?|binding-associated region:283-410 fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33358 uniprotkb:P77334 intact:EBI-1127668|uniprotkb:Q2MAV3|ensemblbacteria:AAC75188|ensemblbacteria:BAE76603 intact:EBI-548149|ensemblbacteria:AAC74367|ensemblbacteria:BAA14839 psi-mi:mlra_ecoli(display_long)|uniprotkb:yehV(gene name synonym)|uniprotkb:MerR-like regulator A(gene name synonym)|uniprotkb:mlrA(gene name)|psi-mi:mlrA(display_short)|uniprotkb:b2127(locus name)|uniprotkb:JW2115(locus name) psi-mi:pder_ecoli(display_long)|uniprotkb:pdeR(gene name)|psi-mi:pdeR(display_short)|uniprotkb:gmr(gene name synonym)|uniprotkb:yciR(gene name synonym)|uniprotkb:JW1278(locus name)|uniprotkb:b1285(locus name) psi-mi:"MI:0018"(two hybrid) Lindenberg et al. (2013) pubmed:23708798|imex:IM-22038 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9096358|imex:IM-22038-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_416631.1|interpro:IPR009061(Putative DNA binding)|interpro:IPR000551(Bacterial regulatory protein, MerR)|refseq:WP_001240401.1|ensemblbacteria:b2127(gene)|ensemblbacteria:BAE76603(gene)|ensemblbacteria:BAE76603(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|ensemblbacteria:AAC75188(transcript)|mint:P33358 refseq:NP_415801.1|refseq:WP_000859945.1|mint:P77334|dip:DIP-11590N|ensemblbacteria:AAC74367(transcript)|ensemblbacteria:b1285(gene)|ensemblbacteria:BAA14839(gene)|ensemblbacteria:BAA14839(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0031280"(negative regulation of cyclase activity)|go:"GO:0071111"(cyclic-guanylate-specific phosphodiesterase activity)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR001633(EAL)|interpro:IPR029787|interpro:IPR035919|interpro:IPR035965|interpro:IPR043128 - - - figure legend:f3a|comment:"Full‐size YdaM did hardly show any indication of interacting with MlrA, nor with the two isolated MlrA domains. However, the isolated YdaM domains showed some interaction with full‐size MlrA. Strikingly, the YdaM‐GGDEF domain alone exhibited strong interaction with MlrA‐CTD, that is, the c‐di‐GMP producing domain of YdaM can make a direct contact with the putative ligand‐binding domain of MlrA. This interaction of MlrA‐CTD was clearly not observed with the full‐size YdaM protein, which means that the presence of the YdaM‐NTD can inhibit a therefore conditional interaction between the YdaM‐GGDEF domain and MlrA‐CTD. Moreover, this interaction was specific, because MlrA‐CTD did not interact with the GGDEF domains of YciR, YegE or YaiC (Figure 3A, lower right panel)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2013/10/21 2014/10/16 rogid:gzJgKnruazPYG9CIb46TIMYA9pg83333 rogid:gf9v5Cxr6btjEHOYbChUilJJQ/083333 intact-crc:2BE1985EB951778E|rigid:PEyvhBv5J8meQM05DzwMD9+SXnU false fusion protein:?-? fusion protein:?-?|binding-associated region:406-658 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P77302 uniprotkb:P77334 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 intact:EBI-548149|ensemblbacteria:AAC74367|ensemblbacteria:BAA14839 psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:pder_ecoli(display_long)|uniprotkb:pdeR(gene name)|psi-mi:pdeR(display_short)|uniprotkb:gmr(gene name synonym)|uniprotkb:yciR(gene name synonym)|uniprotkb:JW1278(locus name)|uniprotkb:b1285(locus name) psi-mi:"MI:0018"(two hybrid) Lindenberg et al. (2013) pubmed:23708798|imex:IM-22038 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9096345|imex:IM-22038-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N refseq:NP_415801.1|refseq:WP_000859945.1|mint:P77334|dip:DIP-11590N|ensemblbacteria:AAC74367(transcript)|ensemblbacteria:b1285(gene)|ensemblbacteria:BAA14839(gene)|ensemblbacteria:BAA14839(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0031280"(negative regulation of cyclase activity)|go:"GO:0071111"(cyclic-guanylate-specific phosphodiesterase activity)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR001633(EAL)|interpro:IPR029787|interpro:IPR035919|interpro:IPR035965|interpro:IPR043128 - - - figure legend:f3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2013/10/21 2014/10/16 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 rogid:gf9v5Cxr6btjEHOYbChUilJJQ/083333 intact-crc:93ED5DAB7DA6B487|rigid:jylK/pTv4FJ0ECpho+GT9c+x9aQ false binding-associated region:283-410|fusion protein:?-? binding-associated region:265-397|fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P77334 uniprotkb:P77302 intact:EBI-548149|ensemblbacteria:AAC74367|ensemblbacteria:BAA14839 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 psi-mi:pder_ecoli(display_long)|uniprotkb:pdeR(gene name)|psi-mi:pdeR(display_short)|uniprotkb:gmr(gene name synonym)|uniprotkb:yciR(gene name synonym)|uniprotkb:JW1278(locus name)|uniprotkb:b1285(locus name) psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:"MI:0018"(two hybrid) Lindenberg et al. (2013) pubmed:23708798|imex:IM-22038 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9096333|imex:IM-22038-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415801.1|refseq:WP_000859945.1|mint:P77334|dip:DIP-11590N|ensemblbacteria:AAC74367(transcript)|ensemblbacteria:b1285(gene)|ensemblbacteria:BAA14839(gene)|ensemblbacteria:BAA14839(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0031280"(negative regulation of cyclase activity)|go:"GO:0071111"(cyclic-guanylate-specific phosphodiesterase activity)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR001633(EAL)|interpro:IPR029787|interpro:IPR035919|interpro:IPR035965|interpro:IPR043128 refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N - - - figure legend:f3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2013/10/21 2014/10/16 rogid:gf9v5Cxr6btjEHOYbChUilJJQ/083333 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 intact-crc:1052519641F4D2A3|rigid:jylK/pTv4FJ0ECpho+GT9c+x9aQ false binding-associated region:406-658|fusion protein:?-? binding-associated region:3-198|fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P77334 uniprotkb:P77302 intact:EBI-548149|ensemblbacteria:AAC74367|ensemblbacteria:BAA14839 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 psi-mi:pder_ecoli(display_long)|uniprotkb:pdeR(gene name)|psi-mi:pdeR(display_short)|uniprotkb:gmr(gene name synonym)|uniprotkb:yciR(gene name synonym)|uniprotkb:JW1278(locus name)|uniprotkb:b1285(locus name) psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:"MI:0018"(two hybrid) Lindenberg et al. (2013) pubmed:23708798|imex:IM-22038 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8803716|imex:IM-22038-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415801.1|refseq:WP_000859945.1|mint:P77334|dip:DIP-11590N|ensemblbacteria:AAC74367(transcript)|ensemblbacteria:b1285(gene)|ensemblbacteria:BAA14839(gene)|ensemblbacteria:BAA14839(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0031280"(negative regulation of cyclase activity)|go:"GO:0071111"(cyclic-guanylate-specific phosphodiesterase activity)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR001633(EAL)|interpro:IPR029787|interpro:IPR035919|interpro:IPR035965|interpro:IPR043128 refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N - - - figure legend:f3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2013/10/21 2014/10/16 rogid:gf9v5Cxr6btjEHOYbChUilJJQ/083333 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 intact-crc:5C72C1BCF99B38B9|rigid:jylK/pTv4FJ0ECpho+GT9c+x9aQ false fusion protein:?-?|binding-associated region:406-658 fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P77302 uniprotkb:P77302 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:"MI:0018"(two hybrid) Lindenberg et al. (2013) pubmed:23708798|imex:IM-22038 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9096422|imex:IM-22038-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N - - - figure legend:f3|comment:"Full‐size YdaM did hardly show any indication of interacting with MlrA, nor with the two isolated MlrA domains. However, the isolated YdaM domains showed some interaction with full‐size MlrA. Strikingly, the YdaM‐GGDEF domain alone exhibited strong interaction with MlrA‐CTD, that is, the c‐di‐GMP producing domain of YdaM can make a direct contact with the putative ligand‐binding domain of MlrA. This interaction of MlrA‐CTD was clearly not observed with the full‐size YdaM protein, which means that the presence of the YdaM‐NTD can inhibit a therefore conditional interaction between the YdaM‐GGDEF domain and MlrA‐CTD. Moreover, this interaction was specific, because MlrA‐CTD did not interact with the GGDEF domains of YciR, YegE or YaiC (Figure 3A, lower right panel)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2013/10/21 2014/10/16 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 intact-crc:3F4EEFB4CCEBD40B|rigid:GMV/cO/djRWDqO8TUm1kphooFsA false binding-associated region:283-410|fusion protein:?-? fusion protein:?-?|binding-associated region:283-410 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P77302 uniprotkb:P77334 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 intact:EBI-548149|ensemblbacteria:AAC74367|ensemblbacteria:BAA14839 psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:pder_ecoli(display_long)|uniprotkb:pdeR(gene name)|psi-mi:pdeR(display_short)|uniprotkb:gmr(gene name synonym)|uniprotkb:yciR(gene name synonym)|uniprotkb:JW1278(locus name)|uniprotkb:b1285(locus name) psi-mi:"MI:0018"(two hybrid) Lindenberg et al. (2013) pubmed:23708798|imex:IM-22038 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9096317|imex:IM-22038-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N refseq:NP_415801.1|refseq:WP_000859945.1|mint:P77334|dip:DIP-11590N|ensemblbacteria:AAC74367(transcript)|ensemblbacteria:b1285(gene)|ensemblbacteria:BAA14839(gene)|ensemblbacteria:BAA14839(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0031280"(negative regulation of cyclase activity)|go:"GO:0071111"(cyclic-guanylate-specific phosphodiesterase activity)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR001633(EAL)|interpro:IPR029787|interpro:IPR035919|interpro:IPR035965|interpro:IPR043128 - - - figure legend:f3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2013/10/21 2014/10/16 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 rogid:gf9v5Cxr6btjEHOYbChUilJJQ/083333 intact-crc:29D1D2F525F0D18D|rigid:jylK/pTv4FJ0ECpho+GT9c+x9aQ false fusion protein:?-?|binding-associated region:3-198 fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P77334 uniprotkb:P33358 intact:EBI-548149|ensemblbacteria:AAC74367|ensemblbacteria:BAA14839 intact:EBI-1127668|uniprotkb:Q2MAV3|ensemblbacteria:AAC75188|ensemblbacteria:BAE76603 psi-mi:pder_ecoli(display_long)|uniprotkb:pdeR(gene name)|psi-mi:pdeR(display_short)|uniprotkb:gmr(gene name synonym)|uniprotkb:yciR(gene name synonym)|uniprotkb:JW1278(locus name)|uniprotkb:b1285(locus name) psi-mi:mlra_ecoli(display_long)|uniprotkb:yehV(gene name synonym)|uniprotkb:MerR-like regulator A(gene name synonym)|uniprotkb:mlrA(gene name)|psi-mi:mlrA(display_short)|uniprotkb:b2127(locus name)|uniprotkb:JW2115(locus name) psi-mi:"MI:0096"(pull down) Lindenberg et al. (2013) pubmed:23708798|imex:IM-22038 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9096477|imex:IM-22038-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415801.1|refseq:WP_000859945.1|mint:P77334|dip:DIP-11590N|ensemblbacteria:AAC74367(transcript)|ensemblbacteria:b1285(gene)|ensemblbacteria:BAA14839(gene)|ensemblbacteria:BAA14839(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0031280"(negative regulation of cyclase activity)|go:"GO:0071111"(cyclic-guanylate-specific phosphodiesterase activity)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR001633(EAL)|interpro:IPR029787|interpro:IPR035919|interpro:IPR035965|interpro:IPR043128 refseq:NP_416631.1|interpro:IPR009061(Putative DNA binding)|interpro:IPR000551(Bacterial regulatory protein, MerR)|refseq:WP_001240401.1|ensemblbacteria:b2127(gene)|ensemblbacteria:BAE76603(gene)|ensemblbacteria:BAE76603(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|ensemblbacteria:AAC75188(transcript)|mint:P33358 - - - figure legend:f2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/21 2014/10/16 rogid:gf9v5Cxr6btjEHOYbChUilJJQ/083333 rogid:gzJgKnruazPYG9CIb46TIMYA9pg83333 intact-crc:678F56D6AE11F0F2|rigid:PEyvhBv5J8meQM05DzwMD9+SXnU false his tag:?-? s tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P77334 uniprotkb:P77302 intact:EBI-548149|ensemblbacteria:AAC74367|ensemblbacteria:BAA14839 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 psi-mi:pder_ecoli(display_long)|uniprotkb:pdeR(gene name)|psi-mi:pdeR(display_short)|uniprotkb:gmr(gene name synonym)|uniprotkb:yciR(gene name synonym)|uniprotkb:JW1278(locus name)|uniprotkb:b1285(locus name) psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:"MI:0096"(pull down) Lindenberg et al. (2013) pubmed:23708798|imex:IM-22038 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9096464|imex:IM-22038-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415801.1|refseq:WP_000859945.1|mint:P77334|dip:DIP-11590N|ensemblbacteria:AAC74367(transcript)|ensemblbacteria:b1285(gene)|ensemblbacteria:BAA14839(gene)|ensemblbacteria:BAA14839(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0031280"(negative regulation of cyclase activity)|go:"GO:0071111"(cyclic-guanylate-specific phosphodiesterase activity)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR001633(EAL)|interpro:IPR029787|interpro:IPR035919|interpro:IPR035965|interpro:IPR043128 refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N - - - figure legend:f2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/21 2014/10/16 rogid:gf9v5Cxr6btjEHOYbChUilJJQ/083333 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 intact-crc:ECCC4F6EB04E1C37|rigid:jylK/pTv4FJ0ECpho+GT9c+x9aQ false his tag:?-? s tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P77302 uniprotkb:P33358 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 intact:EBI-1127668|uniprotkb:Q2MAV3|ensemblbacteria:AAC75188|ensemblbacteria:BAE76603 psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:mlra_ecoli(display_long)|uniprotkb:yehV(gene name synonym)|uniprotkb:MerR-like regulator A(gene name synonym)|uniprotkb:mlrA(gene name)|psi-mi:mlrA(display_short)|uniprotkb:b2127(locus name)|uniprotkb:JW2115(locus name) psi-mi:"MI:0096"(pull down) Lindenberg et al. (2013) pubmed:23708798|imex:IM-22038 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-9096489|imex:IM-22038-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N refseq:NP_416631.1|interpro:IPR009061(Putative DNA binding)|interpro:IPR000551(Bacterial regulatory protein, MerR)|refseq:WP_001240401.1|ensemblbacteria:b2127(gene)|ensemblbacteria:BAE76603(gene)|ensemblbacteria:BAE76603(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|ensemblbacteria:AAC75188(transcript)|mint:P33358 - - - figure legend:f2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/21 2014/10/16 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 rogid:gzJgKnruazPYG9CIb46TIMYA9pg83333 intact-crc:4B7CE8050D53C223|rigid:VcIiYYvkxI2xa7ISIm0HCjMKKm8 false his tag:?-? s tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P77302 uniprotkb:P77302 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:"MI:0030"(cross-linking study) Lindenberg et al. (2013) pubmed:23708798|imex:IM-22038 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9096509|imex:IM-22038-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N - - - figure legend:sf4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/21 2014/10/16 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 intact-crc:DF1818CD94BAF825|rigid:nO4O5kiz3RZqPXq/cKU+RpmiTCA false binding-associated region:3-198|his tag:?-? binding-associated region:3-198|his tag:?-? 4 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P77302 uniprotkb:P77302 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 intact:EBI-544662|uniprotkb:P76846|ensemblbacteria:AAC74423|ensemblbacteria:BAA14945 psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:dgcm_ecoli(display_long)|uniprotkb:dgcM(gene name)|psi-mi:dgcM(display_short)|uniprotkb:ydaM(gene name synonym)|uniprotkb:JW5206(locus name)|uniprotkb:b1341(locus name) psi-mi:"MI:0030"(cross-linking study) Lindenberg et al. (2013) pubmed:23708798|imex:IM-22038 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9096517|imex:IM-22038-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N refseq:NP_415857.2|refseq:WP_000628058.1|ensemblbacteria:AAC74423(transcript)|ensemblbacteria:b1341(gene)|ensemblbacteria:BAA14945(gene)|ensemblbacteria:BAA14945(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0052621"(diguanylate cyclase activity)|go:"GO:1900233"(positive regulation of single-species biofilm formation on inanimate substrate)|go:"GO:1902201"(negative regulation of bacterial-type flagellum-dependent cell motility)|interpro:IPR000014(PAS)|interpro:IPR000160(GGDEF)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR013656(PAS fold-4)|interpro:IPR029787|interpro:IPR035965|interpro:IPR043128|mint:P77302|dip:DIP-28053N - - - figure legend:sf4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/21 2014/10/16 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 rogid:k2eeUyiq/kPj7zxC0IxVBRcadQk83333 intact-crc:2CC4FC833DA58EA8|rigid:nO4O5kiz3RZqPXq/cKU+RpmiTCA false binding-associated region:283-410|his tag:?-? binding-associated region:283-410|his tag:?-? 2 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)