#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6NT76	uniprotkb:P38432	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801033|imex:IM-21643-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	go:"GO:0005634"(nucleus)	-	-	figure legend:f5a sf6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/17	2014/10/16	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	intact-crc:3D9FDE979B3CBF52|rigid:gCgnoA8S1ux61Mg5UY7aFPuHR4U	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q6NT76	uniprotkb:P13010	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801033|imex:IM-21643-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1	refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695	go:"GO:0005634"(nucleus)	-	-	figure legend:f5a sf6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/17	2014/10/16	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606	intact-crc:3D9FDE979B3CBF52|rigid:gCgnoA8S1ux61Mg5UY7aFPuHR4U	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q6NT76	uniprotkb:P12956	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801033|imex:IM-21643-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N	go:"GO:0005634"(nucleus)	-	-	figure legend:f5a sf6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/17	2014/10/16	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	intact-crc:3D9FDE979B3CBF52|rigid:gCgnoA8S1ux61Mg5UY7aFPuHR4U	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q6NT76	uniprotkb:Q9NPE3	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-1642169|ensembl:ENSP00000332198	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:nop10_human(display_long)|uniprotkb:NOLA3(gene name synonym)|uniprotkb:NOP10(gene name)|psi-mi:NOP10(display_short)|uniprotkb:Nucleolar protein family A member 3(gene name synonym)|uniprotkb:snoRNP protein NOP10(gene name synonym)|uniprotkb:Nucleolar protein 10(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801033|imex:IM-21643-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1	refseq:NP_061118.1|dip:DIP-40092N|ensembl:ENSG00000182117(gene)|ensembl:ENST00000328848(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016604"(nuclear body)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR036756|mint:Q9NPE3|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901	go:"GO:0005634"(nucleus)	-	-	figure legend:f5a sf6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/17	2014/10/16	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:gBAwyGcfJTBMf8Q+fQZ/fDcPEBc9606	intact-crc:3D9FDE979B3CBF52|rigid:gCgnoA8S1ux61Mg5UY7aFPuHR4U	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q6NT76	uniprotkb:Q9NX24	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-1050064|uniprotkb:Q9P095|uniprotkb:A6NKY8|intact:EBI-5774108|ensembl:ENSP00000274606	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:nhp2_human(display_long)|uniprotkb:Nucleolar protein family A member 2(gene name synonym)|uniprotkb:snoRNP protein NHP2(gene name synonym)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:NOLA2(gene name synonym)|uniprotkb:HSPC286(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801033|imex:IM-21643-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1	refseq:NP_060308.1|refseq:NP_001030005.1|ensembl:ENSG00000145912(gene)|ensembl:ENST00000274606(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:Q9NX24|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901	go:"GO:0005634"(nucleus)	-	-	figure legend:f5a sf6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/17	2014/10/16	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:ZZchZSzrw15BqMfddUMcaxZRF0w9606	intact-crc:3D9FDE979B3CBF52|rigid:gCgnoA8S1ux61Mg5UY7aFPuHR4U	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q6NT76	uniprotkb:Q9NY12	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-2510382|ensembl:ENSP00000226796|ensembl:ENSP00000378127|uniprotkb:Q5MJQ2	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:gar1_human(display_long)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:NOLA1(gene name synonym)|uniprotkb:snoRNP protein GAR1(gene name synonym)|uniprotkb:Nucleolar protein family A member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801033|imex:IM-21643-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1	ensembl:ENSG00000109534(gene)|ensembl:ENST00000226796(transcript)|ensembl:ENST00000394631(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|mint:Q9NY12|rcsb pdb:7BGB|reactome:R-HSA-171319|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|reactome:R-HSA-6790901|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|refseq:NP_061856.1|refseq:NP_127460.1	go:"GO:0005634"(nucleus)	-	-	figure legend:f5a sf6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/17	2014/10/16	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:voLJvYfWyMWtTf0VSd7XeY3psC09606	intact-crc:3D9FDE979B3CBF52|rigid:gCgnoA8S1ux61Mg5UY7aFPuHR4U	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q6NT76	uniprotkb:O60832	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-713091|ensembl:ENSP00000358563|uniprotkb:O43845|uniprotkb:Q96G67|uniprotkb:Q9Y505|uniprotkb:F5BSB3	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:dkc1_human(display_long)|uniprotkb:Dyskerin(gene name synonym)|uniprotkb:Nucleolar protein family A member 4(gene name synonym)|uniprotkb:snoRNP protein DKC1(gene name synonym)|uniprotkb:Nopp140-associated protein of 57 kDa(gene name synonym)|uniprotkb:Nucleolar protein NAP57(gene name synonym)|uniprotkb:CBF5 homolog(gene name synonym)|uniprotkb:DKC1(gene name)|psi-mi:DKC1(display_short)|uniprotkb:NOLA4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801033|imex:IM-21643-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1	interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR032819|interpro:IPR036974|mint:O60832|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901|interpro:IPR002478(PUA)|ensembl:ENSG00000130826(gene)|ensembl:ENST00000369550(transcript)|go:"GO:0000455"(enzyme-directed rRNA pseudouridine synthesis)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003720"(telomerase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990481"(mRNA pseudouridine synthesis)|go:"GO:0006396"(RNA processing)|refseq:NP_001354.1|refseq:NP_001135935.1|refseq:NP_001275676.1|dip:DIP-40645N	go:"GO:0005634"(nucleus)	-	-	figure legend:f5a sf6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/17	2014/10/16	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:njIdhtX9m37BslwxyAAV/JoRrHo9606	intact-crc:3D9FDE979B3CBF52|rigid:gCgnoA8S1ux61Mg5UY7aFPuHR4U	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P38432	uniprotkb:Q6NT76	intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym)	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801081|imex:IM-21643-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1	go:"GO:0000781"(chromosome, telomeric region)	-	-	figure legend:f5e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/17	2014/10/16	rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	intact-crc:6829CBDBFCAA6314|rigid:KUZKt4py/KWOC/QMXqL0EpPW4Nk	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q8BJA3	uniprotkb:Q9ESX5	intact:EBI-8339554|uniprotkb:Q8BWE7|intact:MINT-4124350|uniprotkb:Q80WC2|uniprotkb:Q99LV1|ensembl:ENSMUSP00000066905	intact:EBI-8339277|uniprotkb:Q3UWE5|intact:MINT-1854010|ensembl:ENSMUSP00000033776	psi-mi:hmbx1_mouse(display_long)|uniprotkb:Hmbox1(gene name)|psi-mi:Hmbox1(display_short)	psi-mi:dkc1_mouse(display_long)|uniprotkb:Dkc1(gene name)|psi-mi:Dkc1(display_short)|uniprotkb:Dyskerin(gene name synonym)|uniprotkb:Nucleolar protein family A member 4(gene name synonym)|uniprotkb:snoRNP protein DKC1(gene name synonym)|uniprotkb:Nopp140-associated protein of 57 kDa(gene name synonym)|uniprotkb:Nucleolar protein NAP57(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801200|imex:IM-21643-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001334555.1|refseq:NP_001334556.1|refseq:XP_011243336.1|refseq:XP_011243337.1|refseq:XP_011243338.1|refseq:NP_796312.2|ensembl:ENSMUSG00000021972(gene)|ensembl:ENSMUST00000067843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q8BJA3	refseq:NP_001025478.1|ensembl:ENSMUSG00000031403(gene)|ensembl:ENSMUST00000033776(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0000455"(enzyme-directed rRNA pseudouridine synthesis)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003720"(telomerase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0033979"(box H/ACA RNA metabolic process)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR032819|interpro:IPR036974|mint:Q9ESX5|reactome:R-MMU-171319	go:"GO:0005634"(nucleus)	function:Putative transcription factor|comment:mint	comment:mint|comment:homomint|function:"Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme"	figure legend:sf6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/10/17	2014/10/16	rogid:xDfQucW3lfyfrqlk5cuHcStfihM10090	rogid:V39Ua6xsNuT1LC5AZN1ZojNyASE10090	intact-crc:83AF7532980B1143|rigid:boP3NsUVTijWA1hzWf2XEuCLs3Y	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q8BJA3	uniprotkb:Q9CRB2	intact:EBI-8339554|uniprotkb:Q8BWE7|intact:MINT-4124350|uniprotkb:Q80WC2|uniprotkb:Q99LV1|ensembl:ENSMUSP00000066905	intact:EBI-8340718|intact:MINT-4125123|ensembl:ENSMUSP00000120014	psi-mi:hmbx1_mouse(display_long)|uniprotkb:Hmbox1(gene name)|psi-mi:Hmbox1(display_short)	psi-mi:nhp2_mouse(display_long)|uniprotkb:Nhp2(gene name)|psi-mi:Nhp2(display_short)|uniprotkb:Nola2(gene name synonym)|uniprotkb:snoRNP protein NHP2(gene name synonym)|uniprotkb:Nucleolar protein family A member 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801200|imex:IM-21643-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001334555.1|refseq:NP_001334556.1|refseq:XP_011243336.1|refseq:XP_011243337.1|refseq:XP_011243338.1|refseq:NP_796312.2|ensembl:ENSMUSG00000021972(gene)|ensembl:ENSMUST00000067843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q8BJA3	refseq:NP_080907.1|ensembl:ENSMUSG00000001056(gene)|ensembl:ENSMUST00000127405(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:Q9CRB2|reactome:R-MMU-171319	go:"GO:0005634"(nucleus)	function:Putative transcription factor|comment:mint	function:"Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (\"psi\") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme"|comment:mint	figure legend:sf6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/10/17	2014/10/16	rogid:xDfQucW3lfyfrqlk5cuHcStfihM10090	rogid:8GeIJuNENgcWIOXcOlRz+wdVujQ10090	intact-crc:83AF7532980B1143|rigid:boP3NsUVTijWA1hzWf2XEuCLs3Y	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q8BJA3	uniprotkb:Q9CQS2	intact:EBI-8339554|uniprotkb:Q8BWE7|intact:MINT-4124350|uniprotkb:Q80WC2|uniprotkb:Q99LV1|ensembl:ENSMUSP00000066905	intact:EBI-8340560|ensembl:ENSMUSP00000028553|intact:MINT-1854127	psi-mi:hmbx1_mouse(display_long)|uniprotkb:Hmbox1(gene name)|psi-mi:Hmbox1(display_short)	psi-mi:nop10_mouse(display_long)|uniprotkb:Nop10(gene name)|psi-mi:Nop10(display_short)|uniprotkb:Nola3(gene name synonym)|uniprotkb:snoRNP protein NOP10(gene name synonym)|uniprotkb:Nucleolar protein 10(gene name synonym)|uniprotkb:Nucleolar protein family A member 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801200|imex:IM-21643-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001334555.1|refseq:NP_001334556.1|refseq:XP_011243336.1|refseq:XP_011243337.1|refseq:XP_011243338.1|refseq:NP_796312.2|ensembl:ENSMUSG00000021972(gene)|ensembl:ENSMUST00000067843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q8BJA3	ensembl:ENSMUSG00000027133(gene)|ensembl:ENSMUST00000028553(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR036756|refseq:NP_079679.1|mint:Q9CQS2|reactome:R-MMU-171319	go:"GO:0005634"(nucleus)	function:Putative transcription factor|comment:mint	function:"Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (\"psi\") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme"|comment:mint	figure legend:sf6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/10/17	2014/10/16	rogid:xDfQucW3lfyfrqlk5cuHcStfihM10090	rogid:gBAwyGcfJTBMf8Q+fQZ/fDcPEBc10090	intact-crc:83AF7532980B1143|rigid:boP3NsUVTijWA1hzWf2XEuCLs3Y	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q8BJA3	uniprotkb:Q5SU73	intact:EBI-8339554|uniprotkb:Q8BWE7|intact:MINT-4124350|uniprotkb:Q80WC2|uniprotkb:Q99LV1|ensembl:ENSMUSP00000066905	intact:EBI-8338103|uniprotkb:Q8VIQ2|uniprotkb:Q9QXI1|uniprotkb:Q8K0K5|intact:MINT-4116771|uniprotkb:Q3TK39|ensembl:ENSMUSP00000103530	psi-mi:hmbx1_mouse(display_long)|uniprotkb:Hmbox1(gene name)|psi-mi:Hmbox1(display_short)	psi-mi:coil_mouse(display_long)|uniprotkb:p80-coilin(gene name synonym)|uniprotkb:Coil(gene name)|psi-mi:Coil(display_short)|uniprotkb:CLN80(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801200|imex:IM-21643-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001334555.1|refseq:NP_001334556.1|refseq:XP_011243336.1|refseq:XP_011243337.1|refseq:XP_011243338.1|refseq:NP_796312.2|ensembl:ENSMUSG00000021972(gene)|ensembl:ENSMUST00000067843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q8BJA3	ensembl:ENSMUSG00000033983(gene)|ensembl:ENSMUST00000107898(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:Q5SU73	go:"GO:0005634"(nucleus)	function:Putative transcription factor|comment:mint	comment:mint	figure legend:sf6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/10/17	2014/10/16	rogid:xDfQucW3lfyfrqlk5cuHcStfihM10090	rogid:Y9k/v3ISMDrvoXbqypGJdEQgzME10090	intact-crc:83AF7532980B1143|rigid:boP3NsUVTijWA1hzWf2XEuCLs3Y	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q8BJA3	uniprotkb:P27641	intact:EBI-8339554|uniprotkb:Q8BWE7|intact:MINT-4124350|uniprotkb:Q80WC2|uniprotkb:Q99LV1|ensembl:ENSMUSP00000066905	intact:EBI-822749|intact:EBI-1216334|uniprotkb:Q3TE46|uniprotkb:Q3TJT0|uniprotkb:Q3TN82|uniprotkb:Q80UT1|uniprotkb:Q8C4N6|uniprotkb:Q8K1K7|uniprotkb:Q9R169|ensembl:ENSMUSP00000027379	psi-mi:hmbx1_mouse(display_long)|uniprotkb:Hmbox1(gene name)|psi-mi:Hmbox1(display_short)	psi-mi:xrcc5_mouse(display_long)|uniprotkb:Xrcc5(gene name)|psi-mi:Xrcc5(display_short)|uniprotkb:G22p2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Ku autoantigen protein p86 homolog(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801200|imex:IM-21643-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001334555.1|refseq:NP_001334556.1|refseq:XP_011243336.1|refseq:XP_011243337.1|refseq:XP_011243338.1|refseq:NP_796312.2|ensembl:ENSMUSG00000021972(gene)|ensembl:ENSMUST00000067843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q8BJA3	refseq:NP_033559.2|ensembl:ENSMUSG00000026187(gene)|ensembl:ENSMUST00000027379(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P27641|reactome:R-MMU-5693571|reactome:R-MMU-6798695	go:"GO:0005634"(nucleus)	function:Putative transcription factor|comment:mint	-	figure legend:sf6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/10/17	2014/10/16	rogid:xDfQucW3lfyfrqlk5cuHcStfihM10090	rogid:481Y2f/7RfAolsvjFd4PhQpJD9810090	intact-crc:83AF7532980B1143|rigid:boP3NsUVTijWA1hzWf2XEuCLs3Y	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q8BJA3	uniprotkb:P23475	intact:EBI-8339554|uniprotkb:Q8BWE7|intact:MINT-4124350|uniprotkb:Q80WC2|uniprotkb:Q99LV1|ensembl:ENSMUSP00000066905	intact:EBI-822760|uniprotkb:Q3UJL8|uniprotkb:Q6GTV8|uniprotkb:Q8QZX7|uniprotkb:O88212|uniprotkb:Q62027|uniprotkb:Q62382|uniprotkb:Q62453	psi-mi:hmbx1_mouse(display_long)|uniprotkb:Hmbox1(gene name)|psi-mi:Hmbox1(display_short)	psi-mi:xrcc6_mouse(display_long)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Ku autoantigen protein p70 homolog(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:Xrcc6(gene name)|psi-mi:Xrcc6(display_short)|uniprotkb:G22p1(gene name synonym)|uniprotkb:Ku70(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801200|imex:IM-21643-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001334555.1|refseq:NP_001334556.1|refseq:XP_011243336.1|refseq:XP_011243337.1|refseq:XP_011243338.1|refseq:NP_796312.2|ensembl:ENSMUSG00000021972(gene)|ensembl:ENSMUST00000067843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q8BJA3	mint:P23475|refseq:NP_034377.2|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|refseq:XP_006520505.1|refseq:XP_006520506.1|refseq:XP_011243758.1|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|go:"GO:0000723"(telomere maintenance)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|reactome:R-MMU-5693571|reactome:R-MMU-6798695	go:"GO:0005634"(nucleus)	function:Putative transcription factor|comment:mint	-	figure legend:sf6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/10/17	2014/10/16	rogid:xDfQucW3lfyfrqlk5cuHcStfihM10090	rogid:/A6ygYkLE2FpziX/3fMu5IvG0iI10090	intact-crc:83AF7532980B1143|rigid:boP3NsUVTijWA1hzWf2XEuCLs3Y	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q8BJA3	uniprotkb:Q9CY66	intact:EBI-8339554|uniprotkb:Q8BWE7|intact:MINT-4124350|uniprotkb:Q80WC2|uniprotkb:Q99LV1|ensembl:ENSMUSP00000066905	intact:EBI-6260856|ensembl:ENSMUSP00000029643|uniprotkb:Q80X93|uniprotkb:Q8VDH0|uniprotkb:Q8C6C5	psi-mi:hmbx1_mouse(display_long)|uniprotkb:Hmbox1(gene name)|psi-mi:Hmbox1(display_short)	psi-mi:gar1_mouse(display_long)|uniprotkb:Nola1(gene name synonym)|uniprotkb:Nucleolar protein family A member 1(gene name synonym)|uniprotkb:snoRNP protein GAR1(gene name synonym)|uniprotkb:Gar1(gene name)|psi-mi:Gar1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8801200|imex:IM-21643-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001334555.1|refseq:NP_001334556.1|refseq:XP_011243336.1|refseq:XP_011243337.1|refseq:XP_011243338.1|refseq:NP_796312.2|ensembl:ENSMUSG00000021972(gene)|ensembl:ENSMUST00000067843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q8BJA3	ensembl:ENSMUSG00000028010(gene)|ensembl:ENSMUST00000029643(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0015030"(Cajal body)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|mint:Q9CY66|reactome:R-MMU-171319|refseq:XP_011238510.1|refseq:NP_080854.1	go:"GO:0005634"(nucleus)	function:Putative transcription factor|comment:mint	-	figure legend:sf6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/10/17	2014/10/16	rogid:xDfQucW3lfyfrqlk5cuHcStfihM10090	rogid:w4y7W3rVMnGQfiS3g/wM6wJtDmc10090	intact-crc:83AF7532980B1143|rigid:boP3NsUVTijWA1hzWf2XEuCLs3Y	false	-	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:Q8BJA3	uniprotkb:P70371	intact:EBI-8339554|uniprotkb:Q8BWE7|intact:MINT-4124350|uniprotkb:Q80WC2|uniprotkb:Q99LV1|ensembl:ENSMUSP00000066905	intact:EBI-6919183|ensembl:ENSMUSP00000140744|uniprotkb:Q9CY71	psi-mi:hmbx1_mouse(display_long)|uniprotkb:Hmbox1(gene name)|psi-mi:Hmbox1(display_short)	psi-mi:terf1_mouse(display_long)|uniprotkb:Terf1(gene name)|psi-mi:Terf1(display_short)|uniprotkb:Trf1(gene name synonym)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8817526|imex:IM-21643-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001334555.1|refseq:NP_001334556.1|refseq:XP_011243336.1|refseq:XP_011243337.1|refseq:XP_011243338.1|refseq:NP_796312.2|ensembl:ENSMUSG00000021972(gene)|ensembl:ENSMUST00000067843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q8BJA3	ensembl:ENSMUSG00000025925(gene)|ensembl:ENSMUST00000188371(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0051301"(cell division)|go:"GO:0005654"(nucleoplasm)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P70371|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-171319|reactome:R-MMU-174411|reactome:R-MMU-174414|reactome:R-MMU-174417|reactome:R-MMU-174430|reactome:R-MMU-174437|reactome:R-MMU-2559586|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|reactome:R-MMU-9670095|refseq:NP_033378.1|dip:DIP-44231N	go:"GO:0000781"(chromosome, telomeric region)	function:Putative transcription factor|comment:mint	-	figure legend:f4b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/10/17	2014/10/16	rogid:xDfQucW3lfyfrqlk5cuHcStfihM10090	rogid:jpK0DXdrNcuBqR96dkp45t/W5+M10090	intact-crc:B86E12249A05DAF9|rigid:xa4+YX79nBKsTC+RHhXXIClOtkE	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q8BJA3	uniprotkb:P70281	intact:EBI-8339554|uniprotkb:Q8BWE7|intact:MINT-4124350|uniprotkb:Q80WC2|uniprotkb:Q99LV1|ensembl:ENSMUSP00000066905	intact:EBI-309380|uniprotkb:Q3V2A4|uniprotkb:Q549A7	psi-mi:hmbx1_mouse(display_long)|uniprotkb:Hmbox1(gene name)|psi-mi:Hmbox1(display_short)	psi-mi:sycp3_mouse(display_long)|uniprotkb:Sycp3(gene name)|psi-mi:Sycp3(display_short)|uniprotkb:Scp3(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8817552|imex:IM-21643-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001334555.1|refseq:NP_001334556.1|refseq:XP_011243336.1|refseq:XP_011243337.1|refseq:XP_011243338.1|refseq:NP_796312.2|ensembl:ENSMUSG00000021972(gene)|ensembl:ENSMUST00000067843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q8BJA3	go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000711"(meiotic DNA repair synthesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0000802"(transverse filament)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|refseq:NP_035647.2|mint:P70281|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051301"(cell division)|go:"GO:0051309"(female meiosis chromosome separation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051878"(lateral element assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:6DD8|rcsb pdb:6DD9	go:"GO:0000781"(chromosome, telomeric region)	function:Putative transcription factor|comment:mint	-	figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/10/17	2014/10/16	rogid:xDfQucW3lfyfrqlk5cuHcStfihM10090	rogid:N9ZI2e0jycvVVkz5xEd63PuK2s410090	intact-crc:F9C4D2F095D1AA52|rigid:7ItZiOI2iaVGsvArcloqyjyOO2o	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9JKX3	uniprotkb:P70281	intact:EBI-8384399|intact:MINT-1857634|uniprotkb:Q99MQ9|uniprotkb:Q920I6|uniprotkb:Q9CPT2|ensembl:ENSMUSP00000031729|ensembl:ENSMUSP00000142478|ensembl:ENSMUSP00000142502|ensembl:ENSMUSP00000142720|ensembl:ENSMUSP00000142814	intact:EBI-309380|uniprotkb:Q3V2A4|uniprotkb:Q549A7	psi-mi:tfr2_mouse(display_long)|uniprotkb:Tfr2(gene name)|psi-mi:Tfr2(display_short)|uniprotkb:Trfr2(gene name synonym)	psi-mi:sycp3_mouse(display_long)|uniprotkb:Sycp3(gene name)|psi-mi:Sycp3(display_short)|uniprotkb:Scp3(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8817561|imex:IM-21643-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011239249.1|refseq:NP_056614.3|refseq:XP_006504656.1|refseq:XP_006504657.1|refseq:NP_001276436.1|refseq:NP_001276438.1|refseq:NP_001276440.1|ensembl:ENSMUSG00000029716(gene)|ensembl:ENSMUST00000031729(transcript)|ensembl:ENSMUST00000196471(transcript)|ensembl:ENSMUST00000198783(transcript)|ensembl:ENSMUST00000198866(transcript)|ensembl:ENSMUST00000199054(transcript)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006953"(acute-phase response)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010039"(response to iron ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033572"(transferrin transport)|go:"GO:0039706"(co-receptor binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0140298"(endocytic iron import into cell)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1990712"(HFE-transferrin receptor complex)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007484(Peptidase M28)|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:Q9JKX3|reactome:R-MMU-917977	go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000711"(meiotic DNA repair synthesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0000802"(transverse filament)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|interpro:IPR006888(Cor1/Xlr/Xmr conserved region)|refseq:NP_035647.2|mint:P70281|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051301"(cell division)|go:"GO:0051309"(female meiosis chromosome separation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051878"(lateral element assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:6DD8|rcsb pdb:6DD9	go:"GO:0000781"(chromosome, telomeric region)	comment:mint|function:Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation	-	figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/10/17	2014/10/16	rogid:ul4WuwejrodaWqBYm0xcLhfuCyg10090	rogid:N9ZI2e0jycvVVkz5xEd63PuK2s410090	intact-crc:8E68E9844C5EC197|rigid:+yKkB6I+Kw8nCBtMsMoNOpXoEdA	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q6NT76	uniprotkb:P70371	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-6919183|ensembl:ENSMUSP00000140744|uniprotkb:Q9CY71	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:terf1_mouse(display_long)|uniprotkb:Terf1(gene name)|psi-mi:Terf1(display_short)|uniprotkb:Trf1(gene name synonym)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8817685|imex:IM-21643-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1	ensembl:ENSMUSG00000025925(gene)|ensembl:ENSMUST00000188371(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0051301"(cell division)|go:"GO:0005654"(nucleoplasm)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P70371|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-171319|reactome:R-MMU-174411|reactome:R-MMU-174414|reactome:R-MMU-174417|reactome:R-MMU-174430|reactome:R-MMU-174437|reactome:R-MMU-2559586|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|reactome:R-MMU-9670095|refseq:NP_033378.1|dip:DIP-44231N	go:"GO:0000781"(chromosome, telomeric region)	-	-	figure legend:sf4b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2013/10/17	2014/10/16	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:jpK0DXdrNcuBqR96dkp45t/W5+M10090	intact-crc:780BE3FF39B1CA58|rigid:QxZ+etgT1Fl/Fr+gUs1NqIxwkWc	false	mutation disrupting interaction:339-339|binding-associated region:267-341	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q5SU73	uniprotkb:Q6NT76	intact:EBI-8338103|uniprotkb:Q8VIQ2|uniprotkb:Q9QXI1|uniprotkb:Q8K0K5|intact:MINT-4116771|uniprotkb:Q3TK39|ensembl:ENSMUSP00000103530	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	psi-mi:coil_mouse(display_long)|uniprotkb:p80-coilin(gene name synonym)|uniprotkb:Coil(gene name)|psi-mi:Coil(display_short)|uniprotkb:CLN80(gene name synonym)	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8817661|imex:IM-21643-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000033983(gene)|ensembl:ENSMUST00000107898(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:Q5SU73	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1	-	comment:mint	-	figure legend:f5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/17	2014/10/16	rogid:Y9k/v3ISMDrvoXbqypGJdEQgzME10090	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	intact-crc:3BAE40BE7555BEA4|rigid:17O1QDsc2BmTtMoQBwGZ1qkcldE	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60832	uniprotkb:Q6NT76	intact:EBI-713091|ensembl:ENSP00000358563|uniprotkb:O43845|uniprotkb:Q96G67|uniprotkb:Q9Y505|uniprotkb:F5BSB3	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	psi-mi:dkc1_human(display_long)|uniprotkb:Dyskerin(gene name synonym)|uniprotkb:Nucleolar protein family A member 4(gene name synonym)|uniprotkb:snoRNP protein DKC1(gene name synonym)|uniprotkb:Nopp140-associated protein of 57 kDa(gene name synonym)|uniprotkb:Nucleolar protein NAP57(gene name synonym)|uniprotkb:CBF5 homolog(gene name synonym)|uniprotkb:DKC1(gene name)|psi-mi:DKC1(display_short)|uniprotkb:NOLA4(gene name synonym)	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8817643|imex:IM-21643-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR032819|interpro:IPR036974|mint:O60832|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901|interpro:IPR002478(PUA)|ensembl:ENSG00000130826(gene)|ensembl:ENST00000369550(transcript)|go:"GO:0000455"(enzyme-directed rRNA pseudouridine synthesis)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003720"(telomerase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990481"(mRNA pseudouridine synthesis)|go:"GO:0006396"(RNA processing)|refseq:NP_001354.1|refseq:NP_001135935.1|refseq:NP_001275676.1|dip:DIP-40645N	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1	-	-	-	figure legend:f5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/17	2014/10/16	rogid:njIdhtX9m37BslwxyAAV/JoRrHo9606	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	intact-crc:850C0092F0FAA6B8|rigid:XvCCvLf/ktKzShkM148TkyNZdk0	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6NT76	uniprotkb:P12956	intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kappei et al. (2013)	imex:IM-21643|pubmed:23685356	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8817668|imex:IM-21643-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N	-	-	-	figure legend:f5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/10/17	2014/10/16	rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	intact-crc:7C46B866191F7109|rigid:6cgjE9UIHlVzg9cfMjXmZYypAZ4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)