#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9VFS8 uniprotkb:Q9V637 intact:EBI-166054|ensemblmetazoa:FBpp0082314 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 psi-mi:psmd9_drome(display_long)|uniprotkb:26S proteasome regulatory subunit p27(gene name synonym)|uniprotkb:CG9588(orf name) psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924349|imex:IM-21136-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-174154|reactome:R-DME-5687128|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-5689603|reactome:R-DME-187577|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-68949|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-69017|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8941858|ensemblmetazoa:FBgn0038166(gene)|ensemblmetazoa:FBtr0082849(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR035269|interpro:IPR036034|interpro:IPR040815|interpro:IPR041489|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|refseq:NP_650301.1|flybase:FBgn0038166 refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2013/08/09 2014/10/16 rogid:SFzf/k/TXFChCQl5mDl95jUGtrM7227 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 intact-crc:05052807805FAB07|rigid:d8sAmscqYUM11GMcugPrQBJEOw8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V637 uniprotkb:Q9VBP3 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 intact:EBI-124451|intact:EBI-500617|uniprotkb:Q9XZ37|ensemblmetazoa:FBpp0084264 psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:tnks_drome(display_long)|uniprotkb:Tnks(gene name)|psi-mi:Tnks(display_short)|uniprotkb:tankyrase(gene name synonym)|uniprotkb:CG4719(orf name)|uniprotkb:Poly [ADP-ribose] polymerase(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924253|imex:IM-21136-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_651410.1|flybase:FBgn0027508|ensemblmetazoa:FBgn0027508(gene)|ensemblmetazoa:FBtr0084890(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR028731|interpro:IPR036770|reactome:R-DME-201681|reactome:R-DME-4641257|reactome:R-DME-5689880|reactome:R-DME-8948751 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2013/08/09 2014/10/16 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 rogid:zB4n+X29JqPu6nif4ym9jnzWGZ47227 intact-crc:6A33CDC50DDBA6BA|rigid:kOU1GMWwoBvUU33LzWB6PTGux7c false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V637 uniprotkb:Q9VYG1 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 intact:EBI-129453|uniprotkb:Q8SZZ0|uniprotkb:A9UNC9|uniprotkb:Q7K0M3|ensemblmetazoa:FBpp0309260|ensemblmetazoa:FBpp0309259|ensemblmetazoa:FBpp0073558 psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:psmd5_drome(display_long)|uniprotkb:26S proteasome subunit S5B(gene name synonym)|uniprotkb:CG12096(orf name) psi-mi:"MI:0047"(far western blotting) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924421|imex:IM-21136-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_572862.2|flybase:FBgn0030457|refseq:NP_001285190.1|refseq:NP_001285191.1|ensemblmetazoa:FBtr0073727(transcript)|ensemblmetazoa:FBtr0340298(transcript)|ensemblmetazoa:FBtr0340299(transcript)|go:"GO:0043248"(proteasome assembly)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019538|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8932339|ensemblmetazoa:FBgn0030457(gene) - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2013/08/09 2014/10/16 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 rogid:FbJcUI8W3A40tX788M/B9WKmWqc7227 intact-crc:A8D6C8D88B21668F|rigid:lKTzAgy7Hcjy9Clmw8wDQNI1Xuk false tag:?-?|32p radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9V637 uniprotkb:Q9VBP3 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 intact:EBI-124451|intact:EBI-500617|uniprotkb:Q9XZ37|ensemblmetazoa:FBpp0084264 psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:tnks_drome(display_long)|uniprotkb:Tnks(gene name)|psi-mi:Tnks(display_short)|uniprotkb:tankyrase(gene name synonym)|uniprotkb:CG4719(orf name)|uniprotkb:Poly [ADP-ribose] polymerase(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase(gene name synonym) psi-mi:"MI:0047"(far western blotting) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924222|imex:IM-21136-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_651410.1|flybase:FBgn0027508|ensemblmetazoa:FBgn0027508(gene)|ensemblmetazoa:FBtr0084890(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR028731|interpro:IPR036770|reactome:R-DME-201681|reactome:R-DME-4641257|reactome:R-DME-5689880|reactome:R-DME-8948751 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2013/08/09 2014/10/16 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 rogid:zB4n+X29JqPu6nif4ym9jnzWGZ47227 intact-crc:936726587350D476|rigid:kOU1GMWwoBvUU33LzWB6PTGux7c false tag:?-?|32p radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9VFS8 uniprotkb:Q9V637 intact:EBI-166054|ensemblmetazoa:FBpp0082314 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 psi-mi:psmd9_drome(display_long)|uniprotkb:26S proteasome regulatory subunit p27(gene name synonym)|uniprotkb:CG9588(orf name) psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:"MI:0047"(far western blotting) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924414|imex:IM-21136-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-174154|reactome:R-DME-5687128|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-5689603|reactome:R-DME-187577|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-68949|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-69017|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8941858|ensemblmetazoa:FBgn0038166(gene)|ensemblmetazoa:FBtr0082849(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR035269|interpro:IPR036034|interpro:IPR040815|interpro:IPR041489|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|refseq:NP_650301.1|flybase:FBgn0038166 refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2013/08/09 2014/10/16 rogid:SFzf/k/TXFChCQl5mDl95jUGtrM7227 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 intact-crc:4351FD492622C821|rigid:d8sAmscqYUM11GMcugPrQBJEOw8 false - tag:?-?|32p radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9VYG1 uniprotkb:Q9XZC3 intact:EBI-129453|uniprotkb:Q8SZZ0|uniprotkb:A9UNC9|uniprotkb:Q7K0M3|ensemblmetazoa:FBpp0309260|ensemblmetazoa:FBpp0309259|ensemblmetazoa:FBpp0073558 intact:EBI-6924616 psi-mi:psmd5_drome(display_long)|uniprotkb:26S proteasome subunit S5B(gene name synonym)|uniprotkb:CG12096(orf name) psi-mi:q9xzc3_drome(display_long)|uniprotkb:Rpt5(gene name)|psi-mi:Rpt5(display_short)|uniprotkb:Tbp-1(gene name synonym)|uniprotkb:CG10370(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924708|imex:IM-21136-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_572862.2|flybase:FBgn0030457|refseq:NP_001285190.1|refseq:NP_001285191.1|ensemblmetazoa:FBtr0073727(transcript)|ensemblmetazoa:FBtr0340298(transcript)|ensemblmetazoa:FBtr0340299(transcript)|go:"GO:0043248"(proteasome assembly)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019538|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8932339|ensemblmetazoa:FBgn0030457(gene) go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|flybase:FBgn0028684 - - - figure legend:Supp. Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/09 2014/10/16 rogid:FbJcUI8W3A40tX788M/B9WKmWqc7227 rogid:rXzKA2nULw2KQV/UaDkcjv/jmP07227 intact-crc:9359CCCAF08199D1|rigid:d5XowBbfgTL2RHSgvsBzGsKZ0Os false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9VFS8 uniprotkb:Q9XZC3 intact:EBI-166054|ensemblmetazoa:FBpp0082314 intact:EBI-6924616 psi-mi:psmd9_drome(display_long)|uniprotkb:26S proteasome regulatory subunit p27(gene name synonym)|uniprotkb:CG9588(orf name) psi-mi:q9xzc3_drome(display_long)|uniprotkb:Rpt5(gene name)|psi-mi:Rpt5(display_short)|uniprotkb:Tbp-1(gene name synonym)|uniprotkb:CG10370(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924632|imex:IM-21136-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-174154|reactome:R-DME-5687128|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-5689603|reactome:R-DME-187577|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-68949|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-69017|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8941858|ensemblmetazoa:FBgn0038166(gene)|ensemblmetazoa:FBtr0082849(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR035269|interpro:IPR036034|interpro:IPR040815|interpro:IPR041489|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|refseq:NP_650301.1|flybase:FBgn0038166 go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|flybase:FBgn0028684 - - - figure legend:Fig. 7A, 7B|comment:ADP-ribosylation considerably increased the ability of PI31 to recruit the assembly chaperones when compared to its unmodified version, sequestering them away from the Rpt base subunits in a dose-dependent manner|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/09 2014/10/16 rogid:SFzf/k/TXFChCQl5mDl95jUGtrM7227 rogid:rXzKA2nULw2KQV/UaDkcjv/jmP07227 intact-crc:4729A4A0EB9CB62F|rigid:LaGBhJtH9t8mmNAJe+2nnfmjqzY false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P18053 uniprotkb:Q9V637 intact:EBI-138951|uniprotkb:Q9W2N9|ensemblmetazoa:FBpp0071451 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 psi-mi:psa4_drome(display_long)|uniprotkb:Prosalpha3(gene name)|psi-mi:Prosalpha3(display_short)|uniprotkb:PROS-29(gene name synonym)|uniprotkb:PROS-Dm29(gene name synonym)|uniprotkb:Pros29(gene name synonym)|uniprotkb:Proteasome 29 kDa subunit(gene name synonym)|uniprotkb:CG9327(orf name) psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924338|imex:IM-21136-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476691.1|flybase:FBgn0261394|dip:DIP-19125N|ensemblmetazoa:FBgn0261394(gene)|ensemblmetazoa:FBtr0071522(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 - - - figure legend:Fig. 4B|comment:Unmodified His-PI31 strongly interacted with alpha-4, whereas binding of the ADP-ribosylated version was significantly diminished|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/09 2014/10/16 rogid:QkNTZwxV/igXkyshRfhWJ5xruyU7227 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 intact-crc:F121C88719D6D660|rigid:LFThtUtUpSQWWf8FpZtFgyxdh54 false flag tag:?-? his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9VFS8 uniprotkb:Q9V637 intact:EBI-166054|ensemblmetazoa:FBpp0082314 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 psi-mi:psmd9_drome(display_long)|uniprotkb:26S proteasome regulatory subunit p27(gene name synonym)|uniprotkb:CG9588(orf name) psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924429|imex:IM-21136-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-174154|reactome:R-DME-5687128|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-5689603|reactome:R-DME-187577|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-68949|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-69017|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8941858|ensemblmetazoa:FBgn0038166(gene)|ensemblmetazoa:FBtr0082849(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR035269|interpro:IPR036034|interpro:IPR040815|interpro:IPR041489|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|refseq:NP_650301.1|flybase:FBgn0038166 refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 - - - figure legend:Fig. 6C, 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/09 2014/10/16 rogid:SFzf/k/TXFChCQl5mDl95jUGtrM7227 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 intact-crc:0955CD22C4B6E28F|rigid:d8sAmscqYUM11GMcugPrQBJEOw8 false mutation disrupting interaction strength:187-187|mutation disrupting interaction strength:9-9|flag tag:?-? ha tag:?-?|necessary binding region:268-270|mutation disrupting interaction strength:241-241|mutation disrupting interaction strength:210-210 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9V637 uniprotkb:P18053 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 intact:EBI-138951|uniprotkb:Q9W2N9|ensemblmetazoa:FBpp0071451 psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:psa4_drome(display_long)|uniprotkb:Prosalpha3(gene name)|psi-mi:Prosalpha3(display_short)|uniprotkb:PROS-29(gene name synonym)|uniprotkb:PROS-Dm29(gene name synonym)|uniprotkb:Pros29(gene name synonym)|uniprotkb:Proteasome 29 kDa subunit(gene name synonym)|uniprotkb:CG9327(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924321|imex:IM-21136-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_476691.1|flybase:FBgn0261394|dip:DIP-19125N|ensemblmetazoa:FBgn0261394(gene)|ensemblmetazoa:FBtr0071522(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-5676590 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/09 2014/10/16 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 rogid:QkNTZwxV/igXkyshRfhWJ5xruyU7227 intact-crc:C57B7ABE49B1E872|rigid:LFThtUtUpSQWWf8FpZtFgyxdh54 false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9VYG1 uniprotkb:Q9XZC3 intact:EBI-129453|uniprotkb:Q8SZZ0|uniprotkb:A9UNC9|uniprotkb:Q7K0M3|ensemblmetazoa:FBpp0309260|ensemblmetazoa:FBpp0309259|ensemblmetazoa:FBpp0073558 intact:EBI-6924616 psi-mi:psmd5_drome(display_long)|uniprotkb:26S proteasome subunit S5B(gene name synonym)|uniprotkb:CG12096(orf name) psi-mi:q9xzc3_drome(display_long)|uniprotkb:Rpt5(gene name)|psi-mi:Rpt5(display_short)|uniprotkb:Tbp-1(gene name synonym)|uniprotkb:CG10370(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924698|imex:IM-21136-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_572862.2|flybase:FBgn0030457|refseq:NP_001285190.1|refseq:NP_001285191.1|ensemblmetazoa:FBtr0073727(transcript)|ensemblmetazoa:FBtr0340298(transcript)|ensemblmetazoa:FBtr0340299(transcript)|go:"GO:0043248"(proteasome assembly)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019538|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8932339|ensemblmetazoa:FBgn0030457(gene) go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|flybase:FBgn0028684 - - - figure legend:Supp. Fig. 6A|comment:ADP-ribosylation considerably increased the ability of PI31 to recruit the assembly chaperones when compared to its unmodified version, sequestering them away from the Rpt base subunits in a dose-dependent manner|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/09 2014/10/16 rogid:FbJcUI8W3A40tX788M/B9WKmWqc7227 rogid:rXzKA2nULw2KQV/UaDkcjv/jmP07227 intact-crc:0A6C98449D11363A|rigid:d5XowBbfgTL2RHSgvsBzGsKZ0Os false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P12881 uniprotkb:Q9V637 intact:EBI-183209|uniprotkb:Q9VL23|uniprotkb:Q8SZ22|ensemblmetazoa:FBpp0079538|ensemblmetazoa:FBpp0310201 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 psi-mi:psa1_drome(display_long)|uniprotkb:Prosalpha6(gene name)|psi-mi:Prosalpha6(display_short)|uniprotkb:PROS-35(gene name synonym)|uniprotkb:PROS-Dm35(gene name synonym)|uniprotkb:Pros35(gene name synonym)|uniprotkb:Proteasome 35 kDa subunit(gene name synonym)|uniprotkb:CG4904(orf name) psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924298|imex:IM-21136-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523532.1|flybase:FBgn0250843|refseq:NP_001285798.1|dip:DIP-22159N|ensemblmetazoa:FBgn0250843(gene)|ensemblmetazoa:FBtr0079948(transcript)|ensemblmetazoa:FBtr0343606(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/09 2014/10/16 rogid:7Bo+D3A0i8CgWm7JEFq/4mPLaNI7227 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 intact-crc:BFA6937BA2BE466C|rigid:xbPJU5cmGhpe9EL6k2h2all8HPk false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9V637 uniprotkb:Q9VBP3 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 intact:EBI-124451|intact:EBI-500617|uniprotkb:Q9XZ37|ensemblmetazoa:FBpp0084264 psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:tnks_drome(display_long)|uniprotkb:Tnks(gene name)|psi-mi:Tnks(display_short)|uniprotkb:tankyrase(gene name synonym)|uniprotkb:CG4719(orf name)|uniprotkb:Poly [ADP-ribose] polymerase(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924268|imex:IM-21136-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_651410.1|flybase:FBgn0027508|ensemblmetazoa:FBgn0027508(gene)|ensemblmetazoa:FBtr0084890(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR028731|interpro:IPR036770|reactome:R-DME-201681|reactome:R-DME-4641257|reactome:R-DME-5689880|reactome:R-DME-8948751 - - - figure legend:Fig. 1C-G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/09 2014/10/16 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 rogid:zB4n+X29JqPu6nif4ym9jnzWGZ47227 intact-crc:665E7DC83A0ECA0B|rigid:kOU1GMWwoBvUU33LzWB6PTGux7c false mutation disrupting interaction strength:210-210|ha tag:?-?|mutation disrupting interaction strength:49-49,54-54|mutation disrupting interaction strength:241-241|necessary binding region:268-270 flag tag:?-?|necessary binding region:1-780(IPR020683) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9XZJ4 uniprotkb:Q9V637 intact:EBI-3416638|uniprotkb:Q0E9G1|uniprotkb:Q9V324|ensemblmetazoa:FBpp0087968|ensemblmetazoa:FBpp0087969|ensemblmetazoa:FBpp0087970|ensemblmetazoa:FBpp0291433 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 psi-mi:psa6_drome(display_long)|uniprotkb:Prosalpha1(gene name)|psi-mi:Prosalpha1(display_short)|uniprotkb:Prosalpha6(gene name synonym)|uniprotkb:20S proteasome subunit alpha-1(gene name synonym)|uniprotkb:CG18495(orf name) psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924329|imex:IM-21136-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163078.1|refseq:NP_524837.2|refseq:NP_724614.1|refseq:NP_724616.1|flybase:FBgn0263121|ensemblmetazoa:FBgn0050382(gene)|ensemblmetazoa:FBgn0263121(gene)|ensemblmetazoa:FBtr0088894(transcript)|ensemblmetazoa:FBtr0088895(transcript)|ensemblmetazoa:FBtr0088896(transcript)|ensemblmetazoa:FBtr0302223(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|reactome:R-DME-1169091|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|go:"GO:0005829"(cytosol)|reactome:R-DME-174184|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|interpro:IPR029055|interpro:IPR034642|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/09 2014/10/16 rogid:2thPE+QOQrQqpSIqormvJVImGB87227 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 intact-crc:408EE8276DDC6E50|rigid:/GE/uIyHSetCwdYl1Ezb9qtFP4U false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9VYG1 uniprotkb:Q9V637 intact:EBI-129453|uniprotkb:Q8SZZ0|uniprotkb:A9UNC9|uniprotkb:Q7K0M3|ensemblmetazoa:FBpp0309260|ensemblmetazoa:FBpp0309259|ensemblmetazoa:FBpp0073558 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 psi-mi:psmd5_drome(display_long)|uniprotkb:26S proteasome subunit S5B(gene name synonym)|uniprotkb:CG12096(orf name) psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924523|imex:IM-21136-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_572862.2|flybase:FBgn0030457|refseq:NP_001285190.1|refseq:NP_001285191.1|ensemblmetazoa:FBtr0073727(transcript)|ensemblmetazoa:FBtr0340298(transcript)|ensemblmetazoa:FBtr0340299(transcript)|go:"GO:0043248"(proteasome assembly)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019538|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|reactome:R-DME-8932339|ensemblmetazoa:FBgn0030457(gene) refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 - - - figure legend:Supp Fig. 5B, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/09 2014/10/16 rogid:FbJcUI8W3A40tX788M/B9WKmWqc7227 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 intact-crc:AF872AB4D84ECB97|rigid:lKTzAgy7Hcjy9Clmw8wDQNI1Xuk false flag tag:?-?|mutation disrupting interaction strength:44-44|mutation disrupting interaction strength:263-263 necessary binding region:268-270|mutation disrupting interaction strength:210-210|mutation disrupting interaction strength:241-241|ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9V5C6 uniprotkb:Q9V637 intact:EBI-131307|uniprotkb:O17313|uniprotkb:Q8MKU6|ensemblmetazoa:FBpp0089041|intact:EBI-451425 intact:EBI-144377|uniprotkb:A4UZD9|uniprotkb:Q0E9B8|ensemblmetazoa:FBpp0087157|ensemblmetazoa:FBpp0087158|ensemblmetazoa:FBpp0087159|ensemblmetazoa:FBpp0301842|ensemblmetazoa:FBpp0301844 psi-mi:psa3_drome(display_long)|uniprotkb:Prosalpha7(gene name)|psi-mi:Prosalpha7(display_short)|uniprotkb:CG1519(orf name)|uniprotkb:20S proteasome subunit alpha-7(gene name synonym) psi-mi:psmf1_drome(display_long)|uniprotkb:PI31(gene name)|psi-mi:PI31(display_short)|uniprotkb:CG8979(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cho-Park et al. (2013) pubmed:23622245|imex:IM-21136 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6924313|imex:IM-21136-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0023175|refseq:NP_724834.1|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-538864|reactome:R-DME-5607761|reactome:R-DME-4641257|reactome:R-DME-5607764|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168|ensemblmetazoa:FBgn0023175(gene)|ensemblmetazoa:FBtr0089998(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-209360|reactome:R-DME-209406|reactome:R-DME-209461|reactome:R-DME-216167|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-432395|reactome:R-DME-432524|reactome:R-DME-432626|reactome:R-DME-450408|reactome:R-DME-4608870|dip:DIP-22157N refseq:NP_610715.1|refseq:NP_725092.1|refseq:NP_725093.1|flybase:FBgn0033669|refseq:NP_001260905.1|refseq:NP_001260907.1|dip:DIP-18931N|ensemblmetazoa:FBgn0033669(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070864"(sperm individualization complex)|go:"GO:0090364"(regulation of proteasome assembly)|interpro:IPR021625|reactome:R-DME-1169091|reactome:R-DME-1234176|reactome:R-DME-1236978|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-202424|reactome:R-DME-2467813|reactome:R-DME-2871837|reactome:R-DME-350562|reactome:R-DME-382556|reactome:R-DME-450408|reactome:R-DME-4608870|reactome:R-DME-4641257|reactome:R-DME-4641258|reactome:R-DME-5358346|reactome:R-DME-5607761|ensemblmetazoa:FBtr0088051(transcript)|reactome:R-DME-5607764|reactome:R-DME-5610780|ensemblmetazoa:FBtr0088052(transcript)|ensemblmetazoa:FBtr0088053(transcript)|ensemblmetazoa:FBtr0310157(transcript)|ensemblmetazoa:FBtr0310159(transcript)|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5668541|reactome:R-DME-5676590|reactome:R-DME-5687128|reactome:R-DME-5689603|reactome:R-DME-5689880|reactome:R-DME-68827|reactome:R-DME-68949|go:"GO:0000502"(proteasome complex)|reactome:R-DME-69017|reactome:R-DME-69601|reactome:R-DME-75815|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939236|reactome:R-DME-8939902|reactome:R-DME-8941858|reactome:R-DME-8948751|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-983168 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/09 2014/10/16 rogid:UfhsRQS5heRBYuwhZfbDMLiQNtg7227 rogid:4NaOnYnaJmKAgnRHW5JpHOto1q87227 intact-crc:B98804735431D377|rigid:qNQu5VDyyXT4e0UUk6oAOWDYBiE false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)