#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
chebi:"CHEBI:34159"	uniprotkb:Q9H900	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1001239|uniprotkb:Q6N049|uniprotkb:Q96SY7|uniprotkb:Q9NWG7|uniprotkb:Q8N404|uniprotkb:B3KVB8|ensembl:ENSP00000311429	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:zwilc_human(display_long)|uniprotkb:ZWILCH(gene name)|psi-mi:ZWILCH(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060445.3|refseq:NP_001274750.1|refseq:NP_001274751.1|refseq:NP_001274752.1|dip:DIP-36478N|ensembl:ENSG00000174442(gene)|ensembl:ENST00000307897(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:1990423"(RZZ complex)|interpro:IPR018630|rcsb pdb:3IF8|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:pIk5I4Y9Qk7AxO0KhWURdlvUu/Y9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P17612	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-476586|uniprotkb:Q32P54|uniprotkb:Q9H2Y0|uniprotkb:Q9NRB4|uniprotkb:Q9NRH9|ensembl:ENSP00000309591|ensembl:ENSP00000499940	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:kapca_human(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)|uniprotkb:PKACA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002721.1|refseq:NP_997401.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|ensembl:ENSG00000072062(gene)|ensembl:ENSG00000288516(gene)|ensembl:ENST00000308677(transcript)|ensembl:ENST00000673550(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:0046827"(positive regulation of protein export from nucleus)|rcsb pdb:5IZJ|rcsb pdb:5J5X|rcsb pdb:5N23|rcsb pdb:5UZK|rcsb pdb:6BYR|rcsb pdb:6BYS|rcsb pdb:6C0U|rcsb pdb:6FRX|rcsb pdb:6NO7|rcsb pdb:6QJ7|rcsb pdb:6WJF|rcsb pdb:6WJG|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|rcsb pdb:3MVJ|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3NX8|interpro:IPR044109|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|mint:P17612|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:4AE6|rcsb pdb:2GU8|rcsb pdb:4AE9|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:3AGL|rcsb pdb:3AGM|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:4WB8|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5IZF|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-512988|reactome:R-HSA-5578775|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8854518|reactome:R-HSA-380320|reactome:R-HSA-8963896|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9010642|refseq:NP_001291278.1|dip:DIP-33878N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:7yhAi67qjSKPIff2dwqjScPXEYM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9UQ16	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1111783|uniprotkb:A9Z1Y1|uniprotkb:O14982|uniprotkb:O95555|uniprotkb:Q1MTM8|uniprotkb:Q5W129|uniprotkb:Q9H0P3|uniprotkb:Q9H548|uniprotkb:Q9NQ68|uniprotkb:Q9NQN6|uniprotkb:Q6P2G1|ensembl:ENSP00000347457	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dyn3_human(display_long)|uniprotkb:KIAA0820(gene name synonym)|uniprotkb:DNM3(gene name)|psi-mi:DNM3(display_short)|uniprotkb:Dynamin, testicular(gene name synonym)|uniprotkb:T-dynamin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001265181.1|refseq:NP_001129599.1|refseq:NP_056384.2|refseq:XP_005245136.1|refseq:XP_005245137.1|ensembl:ENSG00000197959(gene)|ensembl:ENST00000355305(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0006897"(endocytosis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031798"(type 1 metabotropic glutamate receptor binding)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043197"(dendritic spine)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0061828"(apical tubulobulbar complex)|go:"GO:0061829"(basal tubulobulbar complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|rcsb pdb:3L43|rcsb pdb:5A3F|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-2132295|go:"GO:0050803"(regulation of synapse structure or activity)|reactome:R-HSA-8856828|reactome:R-HSA-437239|dip:DIP-36244N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:t1g0cjVLI4Bf0hbMJvoM4zKkVYk9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q6DD88	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6165882|ensembl:ENSP00000381844|uniprotkb:Q8N7W5|uniprotkb:Q9H8Q5|uniprotkb:Q9UFL1	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:atla3_human(display_long)|uniprotkb:ATL3(gene name)|psi-mi:ATL3(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6DD88|rcsb pdb:5VGR|rcsb pdb:6XJO|go:"GO:0007030"(Golgi organization)|ensembl:ENSG00000184743(gene)|ensembl:ENST00000398868(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001276977.1|refseq:NP_056274.3	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:9vgpZvUg5aFAZyNiZ2pdEPn/J7o9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15349	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1384149|uniprotkb:Q15419|uniprotkb:Q59GJ3|uniprotkb:Q5TI68|uniprotkb:Q96J38|uniprotkb:Q9UJN5|uniprotkb:B3KTK9|ensembl:ENSP00000265678	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ks6a2_human(display_long)|uniprotkb:RPS6KA2(gene name)|psi-mi:RPS6KA2(display_short)|uniprotkb:RSK3(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 2(gene name synonym)|uniprotkb:MAPKAPK1C(gene name synonym)|uniprotkb:Ribosomal S6 kinase 3(gene name synonym)|uniprotkb:pp90RSK3(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1c(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001006933.2|refseq:NP_001305865.1|refseq:NP_001305866.1|refseq:NP_001305867.1|refseq:NP_066958.2|dip:DIP-295N|ensembl:ENSG00000071242(gene)|ensembl:ENST00000265678(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001556"(oocyte maturation)|go:"GO:0002035"(brain renin-angiotensin system)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0060047"(heart contraction)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0072687"(meiotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR041906|interpro:IPR042766|mint:Q15349|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-2559582|reactome:R-HSA-437239|reactome:R-HSA-442742|reactome:R-HSA-444257|reactome:R-HSA-881907	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:990LeSQ83sti7xG5qGEoFLDkubs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q07065	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006816.2|ensembl:ENSG00000136026(gene)|ensembl:ENST00000378026(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042599"(lamellar body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028428|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P13637	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-948169|uniprotkb:Q16732|uniprotkb:Q16735|uniprotkb:Q969K5|ensembl:ENSP00000498113|uniprotkb:B7Z2T0|uniprotkb:B7Z401|uniprotkb:F5H6J6	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:at1a3_human(display_long)|uniprotkb:Sodium pump subunit alpha-3(gene name synonym)|uniprotkb:"Na(+)/K(+) ATPase alpha(III) subunit"(gene name synonym)|uniprotkb:ATP1A3(gene name)|psi-mi:ATP1A3(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_689509.1|ensembl:ENSG00000105409(gene)|ensembl:ENST00000648268(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030424"(axon)|go:"GO:0031090"(organelle membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0099520"(ion antiporter activity involved in regulation of presynaptic membrane potential)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P13637|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|refseq:NP_001243142.1|refseq:NP_001243143.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:iDlxP7yaZPX85GQKmHOe0KvnS2w9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P54886	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1210304|ensembl:ENSP00000360268|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000059573(gene)|ensembl:ENST00000371224(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0006592"(ornithine biosynthetic process)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|refseq:NP_001017423.1|refseq:NP_002851.2|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q8NBU5	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2511886|ensembl:ENSP00000339016|ensembl:ENSP00000339017|ensembl:ENSP00000489353|ensembl:ENSP00000489455|ensembl:ENSP00000506333|uniprotkb:Q6P4B9|uniprotkb:Q969Y3|uniprotkb:Q8WYR9|uniprotkb:Q8N3G1|uniprotkb:Q6DKG1|uniprotkb:D3DR26	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:atad1_human(display_long)|uniprotkb:ATAD1(gene name)|psi-mi:ATAD1(display_short)|uniprotkb:Thorase(gene name synonym)|uniprotkb:FNP001(orf name)|uniprotkb:ATPase family AAA domain-containing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000138138(gene)|ensembl:ENSG00000283024(gene)|ensembl:ENST00000308448(transcript)|ensembl:ENST00000328142(transcript)|ensembl:ENST00000634773(transcript)|ensembl:ENST00000634970(transcript)|ensembl:ENST00000680024(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|reactome:R-HSA-9603798|refseq:NP_116199.2|refseq:NP_001308896.1|refseq:XP_005270309.1|refseq:XP_016872336.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:IGkIH4udjuFoshP9hMDDK0ARNOg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15155	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-373107|uniprotkb:P78421|uniprotkb:Q8IW21|uniprotkb:Q96DG0|ensembl:ENSP00000287667|ensembl:ENSP00000482008	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:nomo1_human(display_long)|uniprotkb:PM5(gene name synonym)|uniprotkb:NOMO1(gene name)|psi-mi:NOMO1(display_short)|uniprotkb:pM5 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_055102.3|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000103512(gene)|ensembl:ENSG00000274779(gene)|ensembl:ENST00000287667(transcript)|ensembl:ENST00000619292(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR041033|mint:Q15155	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Dvi85VHhwmSC8qfJp1ufqUqPLdE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P50454	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q14240	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-73473|intact:EBI-1058347|uniprotkb:Q96B90|uniprotkb:Q96EA8|intact:EBI-2831835|uniprotkb:Q53XJ6|uniprotkb:D3DNU9|ensembl:ENSP00000326381	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:if4a2_human(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short)|uniprotkb:DDX2B(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001958.2|ensembl:ENSG00000156976(gene)|ensembl:ENST00000323963(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900260"(negative regulation of RNA-directed 5'-3' RNA polymerase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q14240|rcsb pdb:3BOR|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:m9i/jWfsbU+6kQvj1h06x31+awg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O00429	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	crc64:F9521A376B785B71	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P23921	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14744	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-351098|uniprotkb:Q6IBR1|uniprotkb:A8MZ91|uniprotkb:Q9UKH1|uniprotkb:B5BU10|uniprotkb:D3DS33|ensembl:ENSP00000319169|uniprotkb:A8MTP3|uniprotkb:B4DX49|uniprotkb:B4DY30|uniprotkb:E2QRE7	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:anm5_human(display_long)|uniprotkb:PRMT5(gene name)|psi-mi:PRMT5(display_short)|uniprotkb:IBP72(gene name synonym)|uniprotkb:JBP1(gene name synonym)|uniprotkb:HRMT1L5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)|uniprotkb:72 kDa ICln-binding protein(gene name synonym)|uniprotkb:SKB1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001034708.1|refseq:NP_006100.2|refseq:NP_001269882.1|refseq:NP_001269884.1|refseq:NP_001269885.1|ensembl:ENSG00000100462(gene)|ensembl:ENST00000324366(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0097421"(liver regeneration)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR025799|interpro:IPR029063|interpro:IPR035075|interpro:IPR035247|interpro:IPR035248|mint:O14744|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|reactome:R-HSA-6804760|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|dip:DIP-33172N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:EwePjCDiU/fiuKOO+wnoYQ8I57I9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P52272	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-486809|uniprotkb:Q9Y492|uniprotkb:Q15584|uniprotkb:Q8WZ44|uniprotkb:Q96H56|uniprotkb:Q9BWL9|intact:EBI-28985795|ensembl:ENSP00000325376	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:hnrpm_human(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)|uniprotkb:HNRPM(gene name synonym)|uniprotkb:NAGR1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005959.2|refseq:NP_112480.2|ensembl:ENSG00000099783(gene)|ensembl:ENST00000325495(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:P52272|rcsb pdb:2DGV|rcsb pdb:2DH9|rcsb pdb:2DO0|rcsb pdb:2OT8|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|dip:DIP-29336N|ensembl:ENSP00000325376|ensembl:ENST00000348943|ensembl:ENSP00000325732	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:5FnCgrz0xltEkgw3yh70KP2jz5g9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q01518	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2808398|ensembl:ENSP00000361878|ensembl:ENSP00000361883|ensembl:ENSP00000361891|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000131236(gene)|ensembl:ENST00000372792(transcript)|ensembl:ENST00000372797(transcript)|ensembl:ENST00000372805(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028415|interpro:IPR028417|go:"GO:0001667"(ameboidal-type cell migration)|interpro:IPR036222|interpro:IPR036223|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|refseq:XP_005270425.1|dip:DIP-62063N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	crc64:7789D1FAC0D1AB7B	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P49736	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P26641	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15758	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903803"(L-glutamine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|go:"GO:0042470"(melanosome)|ensembl:ENSG00000105281(gene)|ensembl:ENST00000542575(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P50416	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2817330|uniprotkb:Q9BWK0|uniprotkb:Q8TCU0|ensembl:ENSP00000265641|ensembl:ENSP00000446108	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cpt1a_human(display_long)|uniprotkb:CPT1A(gene name)|psi-mi:CPT1A(display_short)|uniprotkb:CPT1(gene name synonym)|uniprotkb:Carnitine O-palmitoyltransferase I, liver isoform(gene name synonym)|uniprotkb:Carnitine palmitoyltransferase 1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001027017.1|refseq:NP_001867.2|refseq:XP_016872709.1|ensembl:ENSG00000110090(gene)|ensembl:ENST00000265641(transcript)|ensembl:ENST00000539743(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006853"(carnitine shuttle)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0045471"(response to ethanol)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0097421"(liver regeneration)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990698"(palmitoleoyltransferase activity)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR032476|interpro:IPR039551|interpro:IPR042231|mint:P50416|rcsb pdb:2LE3|reactome:R-HSA-1368082|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-5362517	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:fmB4d9VHyWPyV0uTf00NkOr/fM49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P49368	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O95373	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-286735|uniprotkb:A6NNM5|uniprotkb:Q1RMF7|uniprotkb:Q9H177|uniprotkb:Q9NTE3|uniprotkb:B2R786|intact:EBI-28976968|ensembl:ENSP00000369042	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ipo7_human(display_long)|uniprotkb:Ran-binding protein 7(gene name synonym)|uniprotkb:IPO7(gene name)|psi-mi:IPO7(display_short)|uniprotkb:RANBP7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000369042|refseq:NP_006382.1|dip:DIP-32574N|ensembl:ENSG00000205339(gene)|ensembl:ENST00000379719(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O95373	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:aaTn9E3/dTUETnNBYr38fk4ZtDo9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P43686	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P28482	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-959949|ensembl:ENSP00000215832|ensembl:ENSP00000381803|uniprotkb:A8CZ64	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-HSA-112411|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|refseq:NP_002736.3|refseq:NP_620407.1|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P28482|rcsb pdb:1PME|go:"GO:0072686"(mitotic spindle)|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|reactome:R-HSA-111995|reactome:R-HSA-112409|ensembl:ENSG00000100030(gene)|ensembl:ENST00000215832(transcript)|ensembl:ENST00000398822(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|dip:DIP-519N|ensembl:ENSP00000215832|ensembl:ENSP00000381803|ensembl:ENST00000544786|ensembl:ENSP00000440842	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O15260	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O00471	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-949824|ensembl:ENSP00000484855|uniprotkb:B2R6C5|intact:EBI-10171392|uniprotkb:Q8IW24	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:exoc5_human(display_long)|uniprotkb:Exocyst complex component Sec10(gene name synonym)|uniprotkb:EXOC5(gene name)|psi-mi:EXOC5(display_short)|uniprotkb:SEC10(gene name synonym)|uniprotkb:SEC10L1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000070367(gene)|ensembl:ENST00000621441(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904019"(epithelial cell apoptotic process)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR009976(Exocyst complex component Sec10)|interpro:IPR033960|mint:O00471|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|refseq:NP_006535.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:UaEk0DAH+boE9+hl8z3VUUI78dM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P56192	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355848|uniprotkb:Q14895|uniprotkb:Q53H14|uniprotkb:Q96A15|uniprotkb:Q96BZ0|uniprotkb:Q9NSE0|uniprotkb:B3KVK7|ensembl:ENSP00000262027	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:symc_human(display_long)|uniprotkb:MARS1(gene name)|psi-mi:MARS1(display_short)|uniprotkb:MARS(gene name synonym)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR000738(WHEP-TRS)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009068(S15/NS1, RNA-binding)|reactome:R-HSA-379716|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR023458|interpro:IPR029038|interpro:IPR033911|interpro:IPR036282|interpro:IPR041598|interpro:IPR041872|mint:P56192|rcsb pdb:2DJV|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5GL7|rcsb pdb:5GOY|rcsb pdb:5Y6L|reactome:R-HSA-2408522|refseq:NP_004981.2|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000166986(gene)|ensembl:ENST00000262027(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004825"(methionine-tRNA ligase activity)|dip:DIP-38164N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:qNZ6XqndlF5KRn/TWFDb5T1GjEc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q13557	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-351018|intact:EBI-1642546|uniprotkb:Q52PK4|uniprotkb:Q59G21|uniprotkb:Q8N553|uniprotkb:Q9UGH6|uniprotkb:Q9UQE9|uniprotkb:A8MVS8|ensembl:ENSP00000339740|ensembl:ENSP00000507073	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:kcc2d_human(display_long)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)|uniprotkb:CAMKD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001212.2|refseq:NP_742112.1|refseq:NP_742113.1|refseq:NP_742125.1|refseq:NP_742126.1|refseq:NP_742127.1|refseq:NP_001308495.1|refseq:NP_001308502.1|refseq:NP_001308509.1|refseq:NP_001308518.1|ensembl:ENSG00000145349(gene)|ensembl:ENST00000342666(transcript)|ensembl:ENST00000683023(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031432"(titin binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901725"(regulation of histone deacetylase activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13557|rcsb pdb:2VN9|rcsb pdb:2W2C|rcsb pdb:2WEL|rcsb pdb:3GP2|rcsb pdb:5VLO|rcsb pdb:6AYW|reactome:R-HSA-111932|reactome:R-HSA-3371571|reactome:R-HSA-399719|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6802946|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-877300|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|interpro:IPR032710|refseq:XP_011530591.1|refseq:XP_011530593.1|dip:DIP-33129N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P38606	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1054757|intact:EBI-10982175|uniprotkb:Q53YD9|uniprotkb:Q96DY6|uniprotkb:Q9UHY3|uniprotkb:B2RBR8|uniprotkb:B7Z1R5|uniprotkb:D3DN75|ensembl:ENSP00000273398	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:vata_human(display_long)|uniprotkb:Vacuolar proton pump subunit alpha(gene name synonym)|uniprotkb:V-ATPase 69 kDa subunit(gene name synonym)|uniprotkb:Vacuolar ATPase isoform VA68(gene name synonym)|uniprotkb:ATP6V1A(gene name)|psi-mi:ATP6V1A(display_short)|uniprotkb:ATP6A1(gene name synonym)|uniprotkb:ATP6V1A1(gene name synonym)|uniprotkb:VPP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001681.2|ensembl:ENSG00000114573(gene)|ensembl:ENST00000273398(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0030133"(transport vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:P38606|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:GqPRFwsl5tDH83kpE8Al7NiYWrI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9NUQ2	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916385|ensembl:ENSP00000285518|ensembl:ENSP00000495562|uniprotkb:Q8IZ47|uniprotkb:Q9BQG4	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:plce_human(display_long)|uniprotkb:AGPAT5(gene name)|psi-mi:AGPAT5(display_short)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 5(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000155189(gene)|ensembl:ENSG00000284980(gene)|ensembl:ENST00000285518(transcript)|ensembl:ENST00000646327(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006639"(acylglycerol metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0016746"(acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR032098|reactome:R-HSA-1483166|refseq:NP_060831.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Osmz6W9W0rS+khEYpiVNvL14S/I9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P51812	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1046616|ensembl:ENSP00000368884|uniprotkb:Q4VAP3|uniprotkb:Q59H26|uniprotkb:Q5JPK8|uniprotkb:Q7Z3Z7|uniprotkb:B2R9V4	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ks6a3_human(display_long)|uniprotkb:Insulin-stimulated protein kinase 1(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1b(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 3(gene name synonym)|uniprotkb:MAPKAPK1B(gene name synonym)|uniprotkb:Ribosomal S6 kinase 2(gene name synonym)|uniprotkb:pp90RSK2(gene name synonym)|uniprotkb:RPS6KA3(gene name)|psi-mi:RPS6KA3(display_short)|uniprotkb:ISPK1(gene name synonym)|uniprotkb:RSK2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007417"(central nervous system development)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043555"(regulation of translation in response to stress)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0045202"(synapse)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|ensembl:ENSG00000177189(gene)|ensembl:ENST00000379565(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_004577.1|interpro:IPR041905|interpro:IPR041906|mint:P51812|rcsb pdb:4D9T|rcsb pdb:4D9U|rcsb pdb:4JG6|rcsb pdb:4JG7|rcsb pdb:4JG8|rcsb pdb:4NUS|rcsb pdb:4NW5|rcsb pdb:4NW6|rcsb pdb:5D9K|rcsb pdb:5D9L|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-2559582|reactome:R-HSA-437239|reactome:R-HSA-442742|reactome:R-HSA-444257|reactome:R-HSA-881907|dip:DIP-38247N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:zkX8NPvSEjVEap7TxboH2SKy9zg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P35609	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P22695	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O43175	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-350495|uniprotkb:Q5SZU3|uniprotkb:Q9BQ01|ensembl:ENSP00000493175|ensembl:ENSP00000493382|uniprotkb:B2RD08	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sera_human(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)|uniprotkb:PGDH3(gene name synonym)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:Malate dehydrogenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006614.2|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:O43175|rcsb pdb:2G76|rcsb pdb:5N53|rcsb pdb:5N6C|rcsb pdb:5NZO|rcsb pdb:5NZP|rcsb pdb:5NZQ|rcsb pdb:5OFM|rcsb pdb:5OFV|ensembl:ENSG00000092621(gene)|ensembl:ENST00000641023(transcript)|ensembl:ENST00000641597(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|rcsb pdb:5OFW|rcsb pdb:6CWA|rcsb pdb:6PLF|rcsb pdb:6PLG|rcsb pdb:6RIH|rcsb pdb:6RJ2|rcsb pdb:6RJ3|rcsb pdb:6RJ5|rcsb pdb:6RJ6|rcsb pdb:7CVP|reactome:R-HSA-977347	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:uzg4EVysd7/zLXBurqwTCFMvqiA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P50993	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2952691|ensembl:ENSP00000354490|uniprotkb:Q9UQ25|uniprotkb:Q86UZ5|uniprotkb:Q5JW74|uniprotkb:Q07059|uniprotkb:D3DVE4	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:at1a2_human(display_long)|uniprotkb:ATP1A2(gene name)|psi-mi:ATP1A2(display_short)|uniprotkb:KIAA0778(gene name synonym)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P50993|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0040011"(locomotion)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0071260"(cellular response to mechanical stimulus)|ensembl:ENST00000361216(transcript)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|go:"GO:0071383"(cellular response to steroid hormone stimulus)|ensembl:ENSG00000018625(gene)|refseq:NP_000693.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:ynyskooKgMdrxv5wwLQ1CFKQ8HE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P60842	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15233	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q14103	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-299674|ensembl:ENSP00000313199|uniprotkb:P07029|uniprotkb:Q01858|uniprotkb:Q14100|uniprotkb:Q14101|uniprotkb:Q14102|uniprotkb:Q4W5A1|uniprotkb:A8K9J2|uniprotkb:Q9UCE8|uniprotkb:Q9UCE9	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:hnrpd_human(display_long)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000138668(gene)|ensembl:ENST00000313899(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q14103|rcsb pdb:1HD0|rcsb pdb:1HD1|rcsb pdb:1IQT|rcsb pdb:1WTB|rcsb pdb:1X0F|rcsb pdb:2Z5N|rcsb pdb:5IM0|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|reactome:R-HSA-450408|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001003810.1|refseq:NP_002129.2|refseq:NP_112737.1|refseq:NP_112738.1|dip:DIP-31163N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q86VP6	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q99873	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q96F07	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2433893|uniprotkb:A6NLT2|uniprotkb:Q53EN5|uniprotkb:Q9NTK4|uniprotkb:Q9ULQ2|uniprotkb:Q9UN29|uniprotkb:D3DQJ3|ensembl:ENSP00000479719	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cyfp2_human(display_long)|uniprotkb:CYFIP2(gene name)|psi-mi:CYFIP2(display_short)|uniprotkb:KIAA1168(gene name synonym)|uniprotkb:PIR121(gene name synonym)|uniprotkb:p53-inducible protein 121(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011532818.1|refseq:NP_001032410.1|refseq:NP_055191.2|refseq:NP_001278650.1|refseq:NP_001278651.1|refseq:XP_016864830.1|ensembl:ENSG00000055163(gene)|ensembl:ENST00000616178(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0031209"(SCAR complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097484"(dendrite extension)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q96F07|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9664422	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:EjzXClJ8fIqHFNSPrDRAjLT8bOM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P13489	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P33991	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-374938|uniprotkb:Q8NEH1|uniprotkb:Q99658|ensembl:ENSP00000262105|ensembl:ENSP00000496964	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:mcm4_human(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:CDC21(gene name synonym)|uniprotkb:CDC21 homolog(gene name synonym)|uniprotkb:P1-CDC21(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005905.2|refseq:NP_877423.1|ensembl:ENSG00000104738(gene)|ensembl:ENST00000262105(transcript)|ensembl:ENST00000649973(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33991|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31729N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:emFkamsHmwBPzoJnPcaL4SaqAlU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	intact:EBI-6916734	intact:EBI-6915594|chebi:"CHEBI:616370"	-	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:yi016_human(display_short)|psi-mi:EBI-6916734(display_long)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	uniprotkb:A6NKZ8(uniprot-removed-ac)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:w1EqXX2OJHNG6/01Uj08aQ+KtXU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P54619	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1181439|ensembl:ENSP00000447433|uniprotkb:B4DDT7|uniprotkb:Q8N7V9	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:aakg1_human(display_long)|uniprotkb:PRKAG1(gene name)|psi-mi:PRKAG1(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001193638.1|refseq:NP_001193639.1|refseq:NP_002724.1|refseq:XP_011536864.1|reactome:R-HSA-9619483|reactome:R-HSA-9613354|ensembl:ENSG00000181929(gene)|ensembl:ENST00000548065(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043531"(ADP binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051170"(import into nucleus)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR039166|mint:P54619|rcsb pdb:2UV4|rcsb pdb:2UV5|rcsb pdb:2UV6|rcsb pdb:2UV7|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|refseq:XP_006719562.1|dip:DIP-39974N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:JNBzPdCbcgr37RKb2sk6yVL+7649606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q14566	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P29692	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-358607|uniprotkb:Q969J1|uniprotkb:D3DWK3|intact:EBI-748782|uniprotkb:Q96I38|ensembl:ENSP00000317399|ensembl:ENSP00000378551|ensembl:ENSP00000388261|ensembl:ENSP00000433412|ensembl:ENSP00000433611|ensembl:ENSP00000434448|ensembl:ENSP00000434872|ensembl:ENSP00000436542|ensembl:ENSP00000436933|ensembl:ENSP00000478340|ensembl:ENSP00000479653|ensembl:ENSP00000483527|ensembl:ENSP00000487680|intact:EBI-11048966|uniprotkb:Q4VBZ6|uniprotkb:B4DDU4|uniprotkb:E9PBQ9	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ef1d_human(display_long)|uniprotkb:EEF1D(gene name)|psi-mi:EEF1D(display_short)|uniprotkb:EF1D(gene name synonym)|uniprotkb:Antigen NY-CO-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001123528.1|refseq:NP_001123527.1|refseq:NP_001123529.1|refseq:NP_001951.2|refseq:XP_011515207.1|refseq:XP_011515208.1|ensembl:ENST00000419152(transcript)|ensembl:ENST00000529272(transcript)|ensembl:ENST00000530191(transcript)|ensembl:ENST00000530445(transcript)|ensembl:ENST00000531218(transcript)|ensembl:ENST00000533494(transcript)|ensembl:ENST00000534380(transcript)|ensembl:ENST00000614575(transcript)|ensembl:ENST00000615067(transcript)|ensembl:ENST00000615698(transcript)|ensembl:ENST00000632587(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0009299"(mRNA transcription)|go:"GO:0010941"(regulation of cell death)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|mint:P29692|rcsb pdb:2MVM|rcsb pdb:2MVN|rcsb pdb:2N51|rcsb pdb:5JPO|reactome:R-HSA-156842|ensembl:ENSG00000104529(gene)|ensembl:ENSG00000273594(gene)|ensembl:ENST00000317198(transcript)|ensembl:ENST00000395119(transcript)|refseq:NP_001304672.1|refseq:NP_001182132.1|refseq:NP_001276879.1|refseq:XP_006716585.1|refseq:XP_006716586.1|refseq:XP_006716587.1|refseq:XP_006716588.1|refseq:XP_005250880.1|refseq:NP_001317575.1|refseq:XP_016868659.1|refseq:NP_001123525.2|refseq:NP_115754.3	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:9Mzpfofeg2W/GQ/JfjFxcCFJnKg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q16630	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-358410|uniprotkb:Q53ES1|uniprotkb:Q9BSJ7|uniprotkb:Q9BW18|intact:EBI-740029|uniprotkb:A8K7K9|ensembl:ENSP00000391774	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cpsf6_human(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_008938.2|refseq:NP_001287876.1|ensembl:ENSG00000111605(gene)|ensembl:ENST00000435070(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042382"(paraspeckles)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990448"(exon-exon junction complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034769|interpro:IPR034772|interpro:IPR035979|mint:Q16630|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:4B4N|rcsb pdb:4U0A|rcsb pdb:4U0B|rcsb pdb:4WYM|rcsb pdb:6AY9|rcsb pdb:6GX9|reactome:R-HSA-1839117|reactome:R-HSA-5655302|dip:DIP-34501N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:nvZBuI+X/m+5MGIsfh2ToVe5nFs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q13724	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-720141|uniprotkb:Q17RN9|uniprotkb:Q8TCT5|uniprotkb:A8K938|ensembl:ENSP00000410992|uniprotkb:F5H6D0	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:mogs_human(display_long)|uniprotkb:Processing A-glucosidase I(gene name synonym)|uniprotkb:MOGS(gene name)|psi-mi:MOGS(display_short)|uniprotkb:GCS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001139630.1|refseq:NP_006293.2|ensembl:ENSG00000115275(gene)|ensembl:ENST00000448666(transcript)|go:"GO:0004573"(Glc3Man9GlcNAc2 oligosaccharide glucosidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0015926"(glucosidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004888(Glycoside hydrolase, family 63)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR031335|interpro:IPR031631|interpro:IPR038518|mint:Q13724|reactome:R-HSA-4793954|reactome:R-HSA-532668|reactome:R-HSA-9683686|reactome:R-HSA-9694548	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:odbL3NUcP483ilKg/CMVn2GtdVs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15833	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-4401015|uniprotkb:Q9BU65|uniprotkb:B4E175|uniprotkb:E7EQD5|ensembl:ENSP00000221283	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:stxb2_human(display_long)|uniprotkb:STXBP2(gene name)|psi-mi:STXBP2(display_short)|uniprotkb:UNC18B(gene name synonym)|uniprotkb:Protein unc-18 homolog 2(gene name synonym)|uniprotkb:Protein unc-18 homolog B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001120868.1|refseq:NP_008880.2|refseq:NP_001258963.1|ensembl:ENSG00000076944(gene)|ensembl:ENST00000221283(transcript)|go:"GO:0001909"(leukocyte mediated cytotoxicity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030348"(syntaxin-3 binding)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0044194"(cytolytic granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070820"(tertiary granule)|go:"GO:0098793"(presynapse)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|rcsb pdb:4CCA|reactome:R-HSA-114608|reactome:R-HSA-449836	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:KNJQ1UD62S+WDYG1zWW0NOjVmLc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q99832	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O00410	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219|ensembl:ENSP00000418393|ensembl:ENSP00000499125	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002262.3|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|ensembl:ENSG00000065150(gene)|ensembl:ENST00000357602(transcript)|ensembl:ENST00000490680(transcript)|ensembl:ENST00000651721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|refseq:XP_005254109.1|refseq:XP_005254110.1|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_016876051.1|dip:DIP-41042N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P62195	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	crc64:29C6410C4A85A7F7	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P22694	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2679622|uniprotkb:Q14VH1|uniprotkb:Q5BNF3|uniprotkb:Q96B09|uniprotkb:Q59GC0|uniprotkb:Q5BNF2|uniprotkb:Q8IYR5|uniprotkb:Q8IZQ0|uniprotkb:Q5BNE9|uniprotkb:B4E2Q1|uniprotkb:Q7Z3M1|uniprotkb:Q5BNF1|uniprotkb:Q5CZ92|uniprotkb:Q5T1K3|uniprotkb:Q5BNF0|uniprotkb:B4DKB0|uniprotkb:B1APG4|ensembl:ENSP00000359723	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:kapcb_human(display_long)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001229786.1|refseq:NP_001229787.1|refseq:NP_001229788.1|refseq:NP_001229789.1|refseq:NP_001229790.1|refseq:NP_001229791.1|refseq:NP_002722.1|refseq:NP_891993.1|refseq:NP_997461.1|refseq:XP_005271076.1|refseq:XP_006710821.1|refseq:NP_001287844.1|refseq:NP_001287845.1|refseq:NP_001287846.1|ensembl:ENSG00000142875(gene)|ensembl:ENST00000370689(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P22694|interpro:IPR044109|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8963896|reactome:R-HSA-9010642|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:FEzsjRJZlkFu5+KK4abzu7oAY9E9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9Y4E8	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:A0FGR8	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q8NF50	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2548605|uniprotkb:B7ZLP0|uniprotkb:E9PH09|ensembl:ENSP00000394888|uniprotkb:A2A350|uniprotkb:A2BDF2|uniprotkb:A4FU78|uniprotkb:Q3MV16|uniprotkb:Q5JPJ1|uniprotkb:Q8TEP1|uniprotkb:Q8WUY2|uniprotkb:Q9BYJ5|uniprotkb:Q9H1Q2|uniprotkb:Q9H1Q3|uniprotkb:Q9H308|uniprotkb:Q9H7P2|intact:EBI-11070681	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dock8_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011516347.1|refseq:XP_011516349.1|ensembl:ENSG00000107099(gene)|ensembl:ENST00000432829(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061485"(memory T cell proliferation)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-983231|refseq:XP_011516350.1|refseq:NP_001177387.1|refseq:NP_001180465.1|refseq:NP_982272.2|refseq:XP_016870662.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:4ENO+3IOKfCUicfg8fxFQbwf4fg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P47897	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-347462|uniprotkb:B4DWJ2|ensembl:ENSP00000307567	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:syq_human(display_long)|uniprotkb:QARS1(gene name)|psi-mi:QARS1(display_short)|uniprotkb:Glutaminyl-tRNA synthetase(gene name synonym)|uniprotkb:QARS(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005042.1|ensembl:ENSG00000172053(gene)|ensembl:ENST00000306125(transcript)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004514(Glutaminyl-tRNA synthetase, class Ic)|interpro:IPR007638(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 2)|interpro:IPR007639(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 1)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR042558|interpro:IPR042559|mint:P47897|rcsb pdb:4R3Z|rcsb pdb:4YE6|rcsb pdb:4YE8|rcsb pdb:4YE9|reactome:R-HSA-2408522|go:"GO:0006469"(negative regulation of protein kinase activity)|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0007420"(brain development)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001259002.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:3Q8LR+aWJJue/ixtD3ZYDpC/D3o9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q86UP2	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|ensembl:ENSP00000378725|ensembl:ENSP00000432149|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001072989.1|refseq:NP_004977.2|ensembl:ENSG00000126777(gene)|ensembl:ENST00000395314(transcript)|ensembl:ENST00000459737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|refseq:XP_011535053.1|refseq:XP_011535055.1|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P12814	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:guTURyt26f1ort4NAlYyabNc+WE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O60664	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-725795|uniprotkb:Q53G77|uniprotkb:Q9BS03|uniprotkb:Q9UBD7|uniprotkb:Q9UP92|uniprotkb:A8K4Y9|intact:EBI-11103673|uniprotkb:K7EQF4|ensembl:ENSP00000221957	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:plin3_human(display_long)|uniprotkb:Cargo selection protein TIP47(gene name synonym)|uniprotkb:47 kDa mannose 6-phosphate receptor-binding protein(gene name synonym)|uniprotkb:Placental protein 17(gene name synonym)|uniprotkb:PLIN3(gene name)|psi-mi:PLIN3(display_short)|uniprotkb:TIP47(gene name synonym)|uniprotkb:M6PRBP1(gene name synonym)|uniprotkb:Mannose-6-phosphate receptor-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001157666.1|refseq:NP_001157661.1|refseq:NP_005808.3|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019915"(lipid storage)|go:"GO:0030133"(transport vesicle)|ensembl:ENSG00000105355(gene)|go:"GO:0045296"(cadherin binding)|interpro:IPR004279(Perilipin)|reactome:R-HSA-163560|reactome:R-HSA-6811440|reactome:R-HSA-9613354|ensembl:ENST00000221957(transcript)|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9706019|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:U+skqZ/oQtQscaEvfdh+AVnCCKA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O60884	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14983	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-359186|uniprotkb:O14984|uniprotkb:A8K5J9|ensembl:ENSP00000349595|uniprotkb:B3KY17	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:at2a1_human(display_long)|uniprotkb:ATP2A1(gene name)|psi-mi:ATP2A1(display_short)|uniprotkb:Calcium pump 1(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004311.1|refseq:NP_775293.1|ensembl:ENSG00000196296(gene)|ensembl:ENST00000357084(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0031673"(H zone)|go:"GO:0031674"(I band)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034704"(calcium channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:0106134"(positive regulation of cardiac muscle cell contraction)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902082"(positive regulation of calcium ion import into sarcoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:O14983|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001273004.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:3cHH/E8HuaFCoTd7hO/0SFTnqtg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q5T2N8	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2880061|ensembl:ENSP00000368062|uniprotkb:Q8N1Z5	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:atd3c_human(display_long)|uniprotkb:ATAD3C(gene name)|psi-mi:ATAD3C(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000215915(gene)|ensembl:ENST00000378785(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T2N8|refseq:NP_001034300.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:JP1/f7Mg8jNYnXeYRsoIxhk6t+s9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O43847	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2371631|uniprotkb:O15241|uniprotkb:O15242|uniprotkb:Q5VUL0|uniprotkb:Q96HB2|uniprotkb:Q9NU57|uniprotkb:A6NI41|ensembl:ENSP00000262679|intact:EBI-6137671	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:nrdc_human(display_long)|uniprotkb:NRDC(gene name)|psi-mi:NRDC(display_short)|uniprotkb:N-arginine dibasic convertase(gene name synonym)|uniprotkb:NRD1(gene name synonym)|uniprotkb:Nardilysin convertase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001095132.1|refseq:NP_001229290.1|refseq:NP_002516.2|ensembl:ENSG00000078618(gene)|ensembl:ENST00000352171(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0009986"(cell surface)|go:"GO:0046872"(metal ion binding)|go:"GO:0048408"(epidermal growth factor binding)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR032632|mint:O43847	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:zvZTk2Q799M8nsREOYmuYPF/x1U9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9BWM7	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1171999|uniprotkb:Q8NCJ0|uniprotkb:Q9NTP4|ensembl:ENSP00000377103	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sfxn3_human(display_long)|uniprotkb:SFXN3(gene name)|psi-mi:SFXN3(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_112233.2|ensembl:ENST00000393459(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)|interpro:IPR004686(Tricarboxylate/iron carrier)|mint:Q9BWM7|ensembl:ENSG00000107819(gene)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Fbem/nUN4NlpIECvuMoF8SjB7ys9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q05655	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-704279|uniprotkb:B2R834|uniprotkb:Q86XJ6|uniprotkb:Q15144|uniprotkb:B0KZ81|ensembl:ENSP00000331602|ensembl:ENSP00000378217|ensembl:ENSP00000498400|ensembl:ENSP00000498623|ensembl:ENSP00000499558	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:kpcd_human(display_long)|uniprotkb:nPKC-delta(gene name synonym)|uniprotkb:PRKCD(gene name)|psi-mi:PRKCD(display_short)|uniprotkb:Tyrosine-protein kinase PRKCD(gene name synonym)|uniprotkb:PKCD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006245.2|refseq:NP_997704.1|refseq:NP_001303256.1|refseq:XP_016862344.1|refseq:XP_016862345.1|refseq:XP_006713322.1|dip:DIP-29954N|ensembl:ENSG00000163932(gene)|ensembl:ENST00000330452(transcript)|ensembl:ENST00000394729(transcript)|ensembl:ENST00000650739(transcript)|ensembl:ENST00000652449(transcript)|ensembl:ENST00000654719(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023021"(termination of signal transduction)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036019"(endolysosome)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0090398"(cellular senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900163"(positive regulation of phospholipid scramblase activity)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:2000303"(regulation of ceramide biosynthetic process)|go:"GO:2000304"(positive regulation of ceramide biosynthetic process)|go:"GO:2000753"(positive regulation of glucosylceramide catabolic process)|go:"GO:2000755"(positive regulation of sphingomyelin catabolic process)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027436|interpro:IPR034667|interpro:IPR035892|mint:Q05655|rcsb pdb:1YRK|reactome:R-HSA-111465|reactome:R-HSA-111933|reactome:R-HSA-114508|reactome:R-HSA-1250196|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-418597|reactome:R-HSA-450520|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5668599|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-8932339|rcsb pdb:2YUU	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:BR/lNGg6f55rGP91akTf8BLkX449606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P31943	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P46379	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P98171	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2796462|uniprotkb:Q14144|uniprotkb:Q86UY3|ensembl:ENSP00000203786	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:rhg04_human(display_long)|uniprotkb:KIAA0131(gene name synonym)|uniprotkb:RGC1(gene name synonym)|uniprotkb:RHOGAP4(gene name synonym)|uniprotkb:Rho-GAP hematopoietic protein C1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 4(gene name synonym)|uniprotkb:p115(gene name synonym)|uniprotkb:ARHGAP4(gene name)|psi-mi:ARHGAP4(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001158213.1|refseq:NP_001657.3|ensembl:ENSG00000089820(gene)|ensembl:ENST00000350060(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|interpro:IPR035678|interpro:IPR036028|mint:P98171|rcsb pdb:2EPD|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|dip:DIP-41592N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:WVlgmfAiXK06tLaxc8utjbtRa2Y9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9H4A4	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916228|ensembl:ENSP00000295640|uniprotkb:Q9BVM9|uniprotkb:Q9H1D4|uniprotkb:Q9NPT7	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ampb_human(display_long)|uniprotkb:RNPEP(gene name)|psi-mi:RNPEP(display_short)|uniprotkb:APB(gene name synonym)|uniprotkb:Arginine aminopeptidase(gene name synonym)|uniprotkb:Arginyl aminopeptidase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_016857511.1|ensembl:ENSG00000176393(gene)|ensembl:ENST00000295640(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR015211(Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal)|interpro:IPR015571(Peptidase M1, aminopeptidase B)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR034015|interpro:IPR038502|interpro:IPR042097|refseq:NP_001306111.1|refseq:NP_001306112.1|refseq:NP_001306113.1|refseq:NP_064601.3|refseq:XP_005245478.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:N2FXWAmyuXPERWM/Xvy+KWtC5YY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P17655	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1028956|uniprotkb:Q16738|uniprotkb:Q6PJT3|uniprotkb:Q8WU26|uniprotkb:Q9HBB1|uniprotkb:A6NDG7|ensembl:ENSP00000295006|uniprotkb:B7ZA96|uniprotkb:E7ES58	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:can2_human(display_long)|uniprotkb:CAPN2(gene name)|psi-mi:CAPN2(display_short)|uniprotkb:CANPL2(gene name synonym)|uniprotkb:Calpain-2 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 2(gene name synonym)|uniprotkb:Calpain M-type(gene name synonym)|uniprotkb:Millimolar-calpain(gene name synonym)|uniprotkb:Calpain large polypeptide L2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001139540.1|refseq:NP_001739.2|ensembl:ENSG00000162909(gene)|ensembl:ENST00000295006(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001824"(blastocyst development)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007565"(female pregnancy)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0005634"(nucleus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029539|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|interpro:IPR042736|mint:P17655|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:2NQA|reactome:R-HSA-1474228|reactome:R-HSA-8862803|interpro:IPR002048(Calcium-binding EF-hand)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:r60XX66kihGVLaa9888soeXjc0M9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q13409	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-742998|ensembl:ENSP00000380308|ensembl:ENSP00000386415|uniprotkb:Q96NG7|uniprotkb:Q96S87|uniprotkb:Q9BXZ5|uniprotkb:Q9NT58|uniprotkb:Q32LY9|uniprotkb:Q53S84|uniprotkb:Q5BJF8|uniprotkb:Q7Z4X1|uniprotkb:D3DPD4|uniprotkb:D3DPD5|uniprotkb:D3DPD6|uniprotkb:B7ZA04	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dc1i2_human(display_long)|uniprotkb:Cytoplasmic dynein intermediate chain 2(gene name synonym)|uniprotkb:Dynein intermediate chain 2, cytosolic(gene name synonym)|uniprotkb:DYNC1I2(gene name)|psi-mi:DYNC1I2(display_short)|uniprotkb:DNCIC2(gene name synonym)|uniprotkb:DNCI2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000077380(gene)|ensembl:ENST00000397119(transcript)|ensembl:ENST00000409773(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0010970"(transport along microtubule)|go:"GO:0031982"(vesicle)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045504"(dynein heavy chain binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR025956|interpro:IPR036322|mint:Q13409|reactome:R-HSA-380270|rcsb pdb:5JPW|reactome:R-HSA-380284|rcsb pdb:6F1T|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|rcsb pdb:6F1U|rcsb pdb:6F1Z|rcsb pdb:6F38|rcsb pdb:6F3A|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|refseq:NP_001369.1|refseq:NP_001258714.1|refseq:NP_001258717.1|refseq:NP_001258718.1|refseq:NP_001258719.1|refseq:NP_001258715.1|refseq:NP_001307811.1|refseq:NP_001307812.1|refseq:NP_001307813.1|refseq:NP_001258716.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:dTj7k9h8BQ+etwfwsE2MEY2nXRM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14841	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-3938544|uniprotkb:Q9Y4Q0|uniprotkb:Q75W65|uniprotkb:A5PKY8|ensembl:ENSP00000480476	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:opla_human(display_long)|uniprotkb:OPLAH(gene name)|psi-mi:OPLAH(display_short)|uniprotkb:5-oxo-L-prolinase(gene name synonym)|uniprotkb:Pyroglutamase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000178814(gene)|ensembl:ENST00000618853(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0017168"("5-oxoprolinase (ATP-hydrolyzing) activity")|go:"GO:0042802"(identical protein binding)|interpro:IPR002821(Hydantoinase/oxoprolinase)|interpro:IPR003692(Hydantoinase B/oxoprolinase)|interpro:IPR008040(Hydantoinaseoxoprolinase, N-terminal)|mint:O14841|reactome:R-HSA-174403|reactome:R-HSA-5578998|refseq:NP_060040.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:9Y4toRkLUqqb+G4+sCVzpeBZe8c9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P33897	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-81045|uniprotkb:Q6GTZ2|ensembl:ENSP00000218104	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:abcd1_human(display_long)|uniprotkb:ABCD1(gene name)|psi-mi:ABCD1(display_short)|uniprotkb:Adrenoleukodystrophy protein(gene name synonym)|uniprotkb:ALD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000024.2|ensembl:ENSG00000101986(gene)|ensembl:ENST00000218104(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0015607"(ABC-type fatty-acyl-CoA transporter activity)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0015919"(peroxisomal membrane transport)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0036113"(very long-chain fatty-acyl-CoA catabolic process)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042758"(long-chain fatty acid catabolic process)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043217"(myelin maintenance)|go:"GO:0043531"(ADP binding)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2001280"(positive regulation of unsaturated fatty acid biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR031237|interpro:IPR036640|reactome:R-HSA-1369062|reactome:R-HSA-2046105|reactome:R-HSA-2046106|reactome:R-HSA-390247|reactome:R-HSA-5684045|reactome:R-HSA-9603798	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:OOgLhjmsfUUUVc5QaFxFk2LRBEA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O00231	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357816|uniprotkb:O00495|uniprotkb:A8K3I7|uniprotkb:E1P663|uniprotkb:Q53FT5|ensembl:ENSP00000261712|ensembl:ENSP00000393185|ensembl:ENSP00000497128	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:psd11_human(display_long)|uniprotkb:PSMD11(gene name)|psi-mi:PSMD11(display_short)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002806.2|refseq:NP_001257411.1|ensembl:ENSG00000108671(gene)|ensembl:ENST00000261712(transcript)|ensembl:ENST00000457654(transcript)|ensembl:ENST00000649012(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|mint:O00231|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5M32|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:BgQKXK7gMMihacRCI+g/pBnRN309606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q12768	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2563794|uniprotkb:A8K4R7|uniprotkb:Q3KQX5|uniprotkb:Q8TBQ2|ensembl:ENSP00000318016	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:wasc5_human(display_long)|uniprotkb:WASHC5(gene name)|psi-mi:WASHC5(display_short)|uniprotkb:KIAA0196(gene name synonym)|uniprotkb:Strumpellin(gene name synonym)|uniprotkb:WASH complex subunit strumpellin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_055661.3|ensembl:ENSG00000164961(gene)|ensembl:ENST00000318410(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034629"|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0071203"(WASH complex)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0140285"(endosome fission)|interpro:IPR019393|mint:Q12768|refseq:XP_016869602.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:9QEw0Z7NIOvpVJtWXcLp67ApJdk9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P50990	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q16891	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P49411	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O43707	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-351526|uniprotkb:O76048|uniprotkb:D6PXK4|ensembl:ENSP00000252699|ensembl:ENSP00000489220|uniprotkb:A4K467	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:actn4_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004915.2|ensembl:ENSG00000130402(gene)|ensembl:ENSG00000282844(gene)|ensembl:ENST00000252699(transcript)|ensembl:ENST00000634960(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:O43707|rcsb pdb:1WLX|rcsb pdb:1YDI|rcsb pdb:2R0O|rcsb pdb:6O31|rcsb pdb:6OA6|reactome:R-HSA-114608|reactome:R-HSA-373753|dip:DIP-33179N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P57737	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916167|uniprotkb:B4DFD6|uniprotkb:B4DL18|uniprotkb:I3L416|uniprotkb:Q17RK4|intact:EBI-10981974|ensembl:ENSP00000251166|ensembl:ENSP00000482646	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:coro7_human(display_long)|uniprotkb:CORO7(gene name)|psi-mi:CORO7(display_short)|uniprotkb:70 kDa WD repeat tumor rejection antigen homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001188401.1|refseq:NP_001188402.1|refseq:NP_078811.3|ensembl:ENSG00000282725(gene)|ensembl:ENST00000251166(transcript)|ensembl:ENST00000614702(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003779"(actin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027331|interpro:IPR036322|ensembl:ENSG00000262246(gene)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:+SqObkzP4+y0Hq7oMaZqyNOKUKs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q00610	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15046	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356367|uniprotkb:A8MSK1|uniprotkb:Q9HB23|uniprotkb:O14946|uniprotkb:Q96J25|ensembl:ENSP00000303043|uniprotkb:D3DUK4	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:syk_human(display_long)|uniprotkb:KARS1(gene name)|psi-mi:KARS1(display_short)|uniprotkb:KARS(gene name synonym)|uniprotkb:KIAA0070(gene name synonym)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001123561.1|refseq:NP_005539.1|go:"GO:0016597"(amino acid binding)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0005739"(mitochondrion)|go:"GO:0070371"(ERK1 and ERK2 cascade)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018149|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR034762|interpro:IPR044136|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:Q15046|go:"GO:0006430"(lysyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|rcsb pdb:3BJU|rcsb pdb:4DPG|go:"GO:0010165"(response to X-ray)|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:6CHD|rcsb pdb:6ILD|rcsb pdb:6ILH|rcsb pdb:7EA9|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|ensembl:ENSG00000065427(gene)|ensembl:ENST00000302445(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002276"(basophil activation involved in immune response)|go:"GO:0002863"(positive regulation of inflammatory response to antigenic stimulus)|go:"GO:0003877"(ATP adenylyltransferase activity)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|dip:DIP-29725N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:YLjIdoUW7DiNp+Pj1OPg8jhnC5w9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15645	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P17812	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1042983|uniprotkb:Q5VW67|uniprotkb:Q96GK6|ensembl:ENSP00000361699|ensembl:ENSP00000497602|ensembl:ENSP00000497744|uniprotkb:D3DPW1|uniprotkb:B4DR64	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pyrg1_human(display_long)|uniprotkb:CTPS1(gene name)|psi-mi:CTPS1(display_short)|uniprotkb:CTP synthetase 1(gene name synonym)|uniprotkb:CTPS(gene name synonym)|uniprotkb:UTP--ammonia ligase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000171793(gene)|ensembl:ENST00000372616(transcript)|ensembl:ENST00000649124(transcript)|ensembl:ENST00000650070(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|mint:P17812|rcsb pdb:2VO1|rcsb pdb:5U03|reactome:R-HSA-499943|refseq:NP_001288166.1|refseq:NP_001896.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:0QkxA3YRejXU0X7dk7zf1XeAMt89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9BSJ8	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9NVI7	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-352007|ensembl:ENSP00000368030|uniprotkb:Q5SV23|uniprotkb:Q8N275|uniprotkb:Q96A50|uniprotkb:B3KPB3|uniprotkb:D2K8Q1|uniprotkb:G3V1I6	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:atd3a_human(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001164006.1|refseq:NP_001164007.1|refseq:NP_060658.3|ensembl:ENSG00000197785(gene)|ensembl:ENST00000378755(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q9NVI7|dip:DIP-33194N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:IZKJEVLLS/DFINgBgO5frizN1P49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q8WXX5	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2349100|uniprotkb:B2RMW6|ensembl:ENSP00000362041	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dnjc9_human(display_long)|uniprotkb:DNAJC9(gene name)|psi-mi:DNAJC9(display_short)|uniprotkb:DnaJ protein SB73(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_056005.1|ensembl:ENSG00000213551(gene)|ensembl:ENST00000372950(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:Q8WXX5|rcsb pdb:7CIZ|rcsb pdb:7CJ0|go:"GO:0005829"(cytosol)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:K1fhi/D2XXu0PXipEvxGKWyDMMI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15459	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1054743|uniprotkb:E9PAW1|ensembl:ENSP00000215793	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sf3a1_human(display_long)|uniprotkb:Spliceosome-associated protein 114(gene name synonym)|uniprotkb:SF3a120(gene name synonym)|uniprotkb:SF3A1(gene name)|psi-mi:SF3A1(display_short)|uniprotkb:SAP114(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005868.1|ensembl:ENSG00000099995(gene)|ensembl:ENST00000215793(transcript)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|rcsb pdb:2DT6|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6QX9|go:"GO:0071005"(U2-type precatalytic spliceosome)|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|interpro:IPR029071|interpro:IPR035563|interpro:IPR035967|mint:Q15459|rcsb pdb:1ZKH|dip:DIP-29164N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:YrIs3RwfjUcDsHCJDgTLMnOUJZM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q13733	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1045632|uniprotkb:Q504T2|uniprotkb:Q8TBN8|uniprotkb:Q8WXA7|uniprotkb:Q8WXH7|uniprotkb:Q8WY13|uniprotkb:Q7Z4I9|ensembl:ENSP00000357060	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:at1a4_human(display_long)|uniprotkb:ATP1A4(gene name)|psi-mi:ATP1A4(display_short)|uniprotkb:ATP1AL2(gene name synonym)|uniprotkb:Sodium pump subunit alpha-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001001734.1|refseq:NP_653300.2|ensembl:ENSG00000132681(gene)|ensembl:ENST00000368081(transcript)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006811"(ion transport)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019900"(kinase binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097733"(photoreceptor cell cilium)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q13733|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:ura8uAZTi5kbS6QnR4X3K8C+gl09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15418	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-963034|uniprotkb:A6NGG4|intact:EBI-1383804|uniprotkb:A8K9K7|uniprotkb:B7Z5J0|ensembl:ENSP00000363283|ensembl:ENSP00000486881|uniprotkb:Q5SVM5|uniprotkb:Q5SVM8|uniprotkb:Q5SVM9|uniprotkb:Q96C05|uniprotkb:Q9BQK2|uniprotkb:B2RDY8|uniprotkb:E9PRI4	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ks6a1_human(display_long)|uniprotkb:RPS6KA1(gene name)|psi-mi:RPS6KA1(display_short)|uniprotkb:RSK1(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:MAPKAPK1A(gene name synonym)|uniprotkb:Ribosomal S6 kinase 1(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000117676(gene)|ensembl:ENSG00000281877(gene)|ensembl:ENST00000374168(transcript)|ensembl:ENST00000629832(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004711"(ribosomal protein S6 kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0106311"|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|interpro:IPR000719(Protein kinase, core)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016239(Ribosomal protein S6 kinase II)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR041906|mint:Q15418|rcsb pdb:2WNT|go:"GO:0043555"(regulation of translation in response to stress)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|rcsb pdb:2Z7Q|rcsb pdb:2Z7R|rcsb pdb:2Z7S|rcsb pdb:3RNY|go:"GO:0045202"(synapse)|rcsb pdb:3TEI|go:"GO:0045597"(positive regulation of cell differentiation)|rcsb pdb:4H3P|rcsb pdb:4NIF|rcsb pdb:5CSF|rcsb pdb:5CSI|rcsb pdb:5CSJ|rcsb pdb:5CSN|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:6TWY|reactome:R-HSA-198753|reactome:R-HSA-199920|reactome:R-HSA-2559582|reactome:R-HSA-437239|reactome:R-HSA-442742|reactome:R-HSA-444257|reactome:R-HSA-881907|refseq:NP_001006666.1|refseq:NP_002944.2|refseq:NP_001317370.1|dip:DIP-29987N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:kx+9PwIH4KR0iTxpv6epDKNqHBE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9UBF2	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1045840|uniprotkb:A6NH74|uniprotkb:Q54AC3|uniprotkb:Q8WVW8|ensembl:ENSP00000402346|uniprotkb:Q2NLA0	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:copg2_human(display_long)|uniprotkb:Gamma-2-coat protein(gene name synonym)|uniprotkb:COPG2(gene name)|psi-mi:COPG2(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001276962.1|refseq:NP_036265.3|ensembl:ENSG00000158623(gene)|ensembl:ENST00000425248(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9UBF2|reactome:R-HSA-6807878|reactome:R-HSA-6811434|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:VEvct8z8lwNWbLs2GFPrKwk1GpE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q09028	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q7Z4Q2	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1051903|uniprotkb:Q8N525|uniprotkb:Q8WV56|uniprotkb:Q96CC9|uniprotkb:Q9NWN7|uniprotkb:A8K1N4|ensembl:ENSP00000299192	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:heat3_human(display_long)|uniprotkb:HEATR3(gene name)|psi-mi:HEATR3(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_891552.1|ensembl:ENSG00000155393(gene)|ensembl:ENST00000299192(transcript)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR016024(Armadillo-type fold)|mint:Q7Z4Q2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:CjdYLKIHc/A29+XYy4VjNNHJSRU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9UKZ1	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O43237	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-715294|uniprotkb:Q8TAT3|uniprotkb:A8K6V1|uniprotkb:B4DZP4|ensembl:ENSP00000258198	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dc1l2_human(display_long)|uniprotkb:Dynein light intermediate chain 2, cytosolic(gene name synonym)|uniprotkb:LIC53/55(gene name synonym)|uniprotkb:DYNC1LI2(gene name)|psi-mi:DYNC1LI2(display_short)|uniprotkb:LIC2(gene name synonym)|uniprotkb:DNCLI2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006132.1|refseq:NP_001273086.1|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0051642"(centrosome localization)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR008467(Dynein light intermediate chain)|interpro:IPR022780|go:"GO:0000776"(kinetochore)|go:"GO:0005524"(ATP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR027417|rcsb pdb:6F1T|rcsb pdb:6F1Y|rcsb pdb:6F38|rcsb pdb:6F3A|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|ensembl:ENSG00000135720(gene)|ensembl:ENST00000258198(transcript)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:WUEd3zgPhcKEe10gtoJ+okX8Zps9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P39656	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457|uniprotkb:B4DJE3|uniprotkb:B4DLI2	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005207.2|ensembl:ENSG00000244038(gene)|ensembl:ENST00000415136(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034097"(response to cytokine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042110"(T cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P46459	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q14974	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P27824	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P13639	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P40227	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P12268	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9BQA1	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:0q4wunYtHalObC8r1wphhelIpr49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P40763	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	crc64:6C00632211C8012D	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P53396	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1042794|uniprotkb:Q13037|uniprotkb:Q9BRL0|uniprotkb:B4E3P0|uniprotkb:B4DIM0|ensembl:ENSP00000253792|ensembl:ENSP00000466259	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:acly_human(display_long)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001087.2|refseq:NP_942127.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR003781(CoA-binding)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR014608(ATP-citrate synthase)|ensembl:ENSG00000131473(gene)|ensembl:ENST00000352035(transcript)|ensembl:ENST00000590151(transcript)|go:"GO:0003878"(ATP citrate synthase activity)|interpro:IPR016102(Succinyl-CoA synthetase-like)|go:"GO:0005524"(ATP binding)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR017866|interpro:IPR032263|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0046872"(metal ion binding)|interpro:IPR033847|rcsb pdb:6O0H|interpro:IPR036291|rcsb pdb:6POE|interpro:IPR036969|rcsb pdb:6POF|rcsb pdb:6QFB|mint:P53396|rcsb pdb:6UI9|rcsb pdb:6UIA|rcsb pdb:3MWD|rcsb pdb:6UUW|rcsb pdb:6UUZ|rcsb pdb:6UV5|rcsb pdb:6Z2H|rcsb pdb:7LIW|rcsb pdb:7LJ9|rcsb pdb:7LLA|reactome:R-HSA-163765|rcsb pdb:3MWE|reactome:R-HSA-6798695|reactome:R-HSA-75105|rcsb pdb:3PFF|rcsb pdb:5TDE|rcsb pdb:5TDF|rcsb pdb:5TDM|rcsb pdb:5TDZ|rcsb pdb:5TE1|rcsb pdb:5TEQ|rcsb pdb:5TES|rcsb pdb:5TET|rcsb pdb:6HXH|rcsb pdb:6HXK|rcsb pdb:6HXL|rcsb pdb:6HXM|refseq:XP_005257452.1|refseq:NP_001290203.1|refseq:NP_001290204.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:NaxO5aRi08GTrEV9aIboUdTlpAs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O00232	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|ensembl:ENSP00000348442|uniprotkb:A6NP15	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002807.1|refseq:NP_001303270.1|ensembl:ENSG00000197170(gene)|ensembl:ENST00000356126(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|rcsb pdb:5VFS|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-5687128|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_777360.1|dip:DIP-27549N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q08043	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2880652|ensembl:ENSP00000426797|uniprotkb:Q4KKV2|uniprotkb:A6NP77	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:actn3_human(display_long)|uniprotkb:ACTN3(gene name)|psi-mi:ACTN3(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 3(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051015"(actin filament binding)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904025"(positive regulation of glucose catabolic process to lactate via pyruvate)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|ensembl:ENSG00000248746(gene)|ensembl:ENST00000513398(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014728"(regulation of the force of skeletal muscle contraction)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0030018"(Z disc)|go:"GO:0031143"(pseudopodium)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0042802"(identical protein binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1TJT|rcsb pdb:1WKU|rcsb pdb:3LUE|reactome:R-HSA-373753|reactome:R-HSA-390522|refseq:NP_001245300.2|refseq:NP_001095.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:ihTlyeKGYaTOZTmd5oP5FeFmo089606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9P2J5	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356077|uniprotkb:Q9NSE1|uniprotkb:A2RRR4|uniprotkb:B4DJ10|uniprotkb:Q2TU79|uniprotkb:A7E266|ensembl:ENSP00000377954	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sylc_human(display_long)|uniprotkb:LARS1(gene name)|psi-mi:LARS1(display_short)|uniprotkb:KIAA1352(gene name synonym)|uniprotkb:LARS(gene name synonym)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_064502.9|refseq:NP_001304893.1|refseq:NP_001304894.1|refseq:NP_057544.2|refseq:XP_011535958.1|ensembl:ENSG00000133706(gene)|ensembl:ENST00000394434(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0012505"(endomembrane system)|go:"GO:0016604"(nuclear body)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR004493(Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|mint:Q9P2J5|rcsb pdb:2WFD|rcsb pdb:6KID|rcsb pdb:6KIE|rcsb pdb:6KQY|rcsb pdb:6KR7|rcsb pdb:6LPF|rcsb pdb:6LR6|reactome:R-HSA-2408522|reactome:R-HSA-379716	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:nlK4kRCik2LLC3VNl0sryrLLnqA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9UH99	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O94905	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14967	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699|ensembl:ENSP00000392782	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132(gene)|ensembl:ENST00000325617(transcript)|ensembl:ENST00000414773(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007338"(single fertilization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Akb2XoiNjob34njC2erE11yg80w9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9NRF8	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-740874|ensembl:ENSP00000352222|ensembl:ENSP00000369590|ensembl:ENSP00000401264|uniprotkb:Q9BRI0|uniprotkb:Q9H809|uniprotkb:Q9H8K9|uniprotkb:B3KWM2	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pyrg2_human(display_long)|uniprotkb:UTP--ammonia ligase 2(gene name synonym)|uniprotkb:CTP synthetase 2(gene name synonym)|uniprotkb:CTPS2(gene name)|psi-mi:CTPS2(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000047230(gene)|refseq:NP_001137474.1|refseq:NP_062831.3|refseq:NP_787055.1|ensembl:ENST00000359276(transcript)|ensembl:ENST00000380241(transcript)|ensembl:ENST00000443824(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|rcsb pdb:2V4U|rcsb pdb:2VKT|rcsb pdb:3IHL|rcsb pdb:6PK4|rcsb pdb:6PK7|reactome:R-HSA-499943|refseq:XP_006724566.1|refseq:XP_005274619.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:BU/tvZTUS1d42+j0qSGAg7ND25Y9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q93084	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1046185|uniprotkb:O60900|uniprotkb:O60901|uniprotkb:O75501|uniprotkb:O75502|uniprotkb:Q16115|uniprotkb:Q8TEX5|uniprotkb:Q8TEX6|uniprotkb:D3DTJ8|uniprotkb:A8MZG0|uniprotkb:Q6JHX1|ensembl:ENSP00000380234	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:at2a3_human(display_long)|uniprotkb:Calcium pump 3(gene name synonym)|uniprotkb:ATP2A3(gene name)|psi-mi:ATP2A3(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_777618.1|refseq:NP_005164.2|refseq:NP_777615.1|refseq:NP_777616.1|refseq:NP_777617.1|refseq:NP_777613.1|refseq:NP_777614.1|ensembl:ENSG00000074370(gene)|ensembl:ENST00000397041(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Nvh6pdcL5m05Wgu5rINDl8bhvDM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9Y6E2	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1051021|uniprotkb:Q3B779|uniprotkb:Q9H3F7|uniprotkb:A4D123|uniprotkb:Q96JW5|ensembl:ENSP00000258761|ensembl:ENSP00000397249	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:bzw2_human(display_long)|uniprotkb:BZW2(gene name)|psi-mi:BZW2(display_short)|uniprotkb:HSPC028(orf name)|uniprotkb:MSTP017(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001153239.1|refseq:NP_054757.1|ensembl:ENSG00000136261(gene)|ensembl:ENST00000258761(transcript)|ensembl:ENST00000433922(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|refseq:XP_006715769.1|refseq:XP_006715770.1|refseq:XP_006715771.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:+z22Ykb6e3IM9zk51m6tjuhiEcU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q01650	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6138761|uniprotkb:Q8IV97|uniprotkb:Q9UBN8|uniprotkb:Q9UP15|uniprotkb:Q9UQC0|ensembl:ENSP00000261622	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:lat1_human(display_long)|uniprotkb:SLC7A5(gene name)|psi-mi:SLC7A5(display_short)|uniprotkb:CD98LC(gene name synonym)|uniprotkb:LAT1(gene name synonym)|uniprotkb:MPE16(gene name synonym)|uniprotkb:4F2 light chain(gene name synonym)|uniprotkb:CD98 light chain(gene name synonym)|uniprotkb:Integral membrane protein E16(gene name synonym)|uniprotkb:L-type amino acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 7 member 5(gene name synonym)|uniprotkb:y+ system cationic amino acid transporter(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003477.4|ensembl:ENSG00000103257(gene)|ensembl:ENST00000261622(transcript)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015196"(L-tryptophan transmembrane transporter activity)|go:"GO:0015349"(thyroid hormone transmembrane transporter activity)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070327"(thyroid hormone transport)|go:"GO:0089718"(amino acid import across plasma membrane)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904556"(L-tryptophan transmembrane transport)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004760(L-type amino acid transporter)|mint:Q01650|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-71240|go:"GO:0015804"(neutral amino acid transport)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:GrXTCUhrHMNCnvscgx1ink2opoU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9ULD0	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-3940481|uniprotkb:A8K2G1|uniprotkb:Q9NVA0|uniprotkb:Q8TAN9|uniprotkb:B4DKG2|uniprotkb:B4E193|ensembl:ENSP00000363216	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ogdhl_human(display_long)|uniprotkb:OGDHL(gene name)|psi-mi:OGDHL(display_short)|uniprotkb:KIAA1290(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1-like(gene name synonym)|uniprotkb:Alpha-ketoglutarate dehydrogenase-like(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011538248.1|ensembl:ENSG00000197444(gene)|ensembl:ENST00000374103(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|mint:Q9ULD0|refseq:NP_001137468.1|refseq:NP_001137469.1|refseq:NP_060715.2|refseq:NP_001334748.1|refseq:NP_001334749.1|refseq:NP_001334751.1|refseq:NP_001334750.1|dip:DIP-61552N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:EDiWt3/TMGuamJ6FgN8l1/whN5g9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P50897	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1237011|intact:EBI-2859371|uniprotkb:Q6FGQ4|uniprotkb:B4DY24|ensembl:ENSP00000432053|ensembl:ENSP00000493153	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ppt1_human(display_long)|uniprotkb:PPT1(gene name)|psi-mi:PPT1(display_short)|uniprotkb:PPT(gene name synonym)|uniprotkb:Palmitoyl-protein hydrolase 1(gene name synonym)|uniprotkb:CLN1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000301.1|refseq:NP_001136076.1|ensembl:ENSG00000131238(gene)|ensembl:ENST00000529905(transcript)|ensembl:ENST00000642050(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007601"(visual perception)|go:"GO:0007625"(grooming behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0016790"(thiolester hydrolase activity)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031579"(membrane raft organization)|go:"GO:0032429"(regulation of phospholipase A2 activity)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0048666"(neuron development)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050896"(response to stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120146"(sulfatide binding)|interpro:IPR002472(Palmitoyl protein thioesterase)|interpro:IPR029058|interpro:IPR030294|mint:P50897|rcsb pdb:3GRO|reactome:R-HSA-75105|go:"GO:0043524"(negative regulation of neuron apoptotic process)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:2G1ae6m4OZsMiRzro/2JmWiOOMA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P12081	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1057566|uniprotkb:B4DY73|uniprotkb:B4DHQ1|uniprotkb:D6REN6|uniprotkb:J3KNE5|ensembl:ENSP00000425634	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:hars1_human(display_long)|uniprotkb:HARS1(gene name)|psi-mi:HARS1(display_short)|uniprotkb:HARS(gene name synonym)|uniprotkb:HRS(gene name synonym)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001244969.1|refseq:NP_002100.2|refseq:NP_001244970.1|refseq:NP_001244971.1|ensembl:ENSG00000170445(gene)|ensembl:ENST00000504156(transcript)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000738(WHEP-TRS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR033656|interpro:IPR036621|interpro:IPR041715|mint:P12081|rcsb pdb:1X59|rcsb pdb:2LW7|rcsb pdb:4G84|rcsb pdb:4G85|rcsb pdb:4PHC|rcsb pdb:4X5O|rcsb pdb:5W6M|rcsb pdb:6O76|reactome:R-HSA-379716|dip:DIP-37596N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:7o34bzWC+/C+mlCDTcvUOHbaCxE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14929	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q14318	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q8TD19	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1044009|uniprotkb:Q52LK6|uniprotkb:Q8NCN0|uniprotkb:Q8TCY4|uniprotkb:Q9UPI4|uniprotkb:Q9Y6S4|uniprotkb:Q9Y6S5|uniprotkb:Q9Y6S6|intact:EBI-28978800|ensembl:ENSP00000238616	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:nek9_human(display_long)|uniprotkb:NEK9(gene name)|psi-mi:NEK9(display_short)|uniprotkb:KIAA1995(gene name synonym)|uniprotkb:NEK8(gene name synonym)|uniprotkb:NERCC(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 9(gene name synonym)|uniprotkb:Nercc1 kinase(gene name synonym)|uniprotkb:NimA-related kinase 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_149107.4|ensembl:ENSG00000119638(gene)|ensembl:ENST00000238616(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011009(Protein kinase-like)|interpro:IPR042767|mint:Q8TD19|rcsb pdb:3ZKE|rcsb pdb:3ZKF|reactome:R-HSA-2980767|reactome:R-HSA-3301854|reactome:R-HSA-9648025|ensembl:ENSP00000238616|refseq:NP_001316166.1|refseq:NP_001316167.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:nH92Hku490dDttw5Akug+NjXRNY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P13797	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-698052|uniprotkb:B1AQ09|uniprotkb:Q86YI6|uniprotkb:A8K579|uniprotkb:B4DGB4|uniprotkb:B7Z6M1|ensembl:ENSP00000348163|ensembl:ENSP00000445339	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:plst_human(display_long)|uniprotkb:T-plastin(gene name synonym)|uniprotkb:PLS3(gene name)|psi-mi:PLS3(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001129497.1|refseq:NP_005023.2|refseq:XP_011535836.1|refseq:NP_001165806.1|refseq:NP_001269266.1|refseq:NP_001269267.1|ensembl:ENSG00000102024(gene)|ensembl:ENST00000355899(transcript)|ensembl:ENST00000539310(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0032432"(actin filament bundle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060348"(bone development)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|mint:P13797|rcsb pdb:1AOA|rcsb pdb:1WJO	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:RWAS8uhDHEtqdDd1gfsqDDyvvsE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P08238	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:wOsW7C10v2oMsM+REE38K6PAan09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P33176	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004512.1|ensembl:ENSG00000170759(gene)|ensembl:ENST00000302418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-29244N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P25098	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-3904795|uniprotkb:Q6GTT3|uniprotkb:B0ZBE1|uniprotkb:Q13837|ensembl:ENSP00000312262	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:arbk1_human(display_long)|uniprotkb:GRK2(gene name)|psi-mi:GRK2(display_short)|uniprotkb:ADRBK1(gene name synonym)|uniprotkb:BARK(gene name synonym)|uniprotkb:BARK1(gene name synonym)|uniprotkb:G-protein coupled receptor kinase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001610.2|dip:DIP-42429N|ensembl:ENSG00000173020(gene)|ensembl:ENST00000308595(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0003108"(negative regulation of the force of heart contraction by chemical signal)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007217"(tachykinin receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019079"(viral genome replication)|go:"GO:0031623"(receptor internalization)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0031755"(Edg-2 lysophosphatidic acid receptor binding)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0005737"(cytoplasm)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1901081"(negative regulation of relaxation of smooth muscle)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|mint:P25098|rcsb pdb:1BAK|rcsb pdb:3CIK|rcsb pdb:3KRW|rcsb pdb:3KRX|rcsb pdb:3V5W|rcsb pdb:4MK0|rcsb pdb:4PNK|rcsb pdb:5HE1|rcsb pdb:5UKK|rcsb pdb:5UKL|rcsb pdb:5UUU|rcsb pdb:5UVC|rcsb pdb:5WG3|rcsb pdb:5WG4|rcsb pdb:5WG5|rcsb pdb:6C2Y|rcsb pdb:6U7C|rcsb pdb:7K7L|rcsb pdb:7K7Z|reactome:R-HSA-111933|reactome:R-HSA-416476|reactome:R-HSA-418555|reactome:R-HSA-5635838|reactome:R-HSA-8856825|go:"GO:0045202"(synapse)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:iAd5kj9koCtmmVivrWfgN4y0YMc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15008	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P22102	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356297|ensembl:ENSP00000371236|ensembl:ENSP00000371253|ensembl:ENSP00000371261|ensembl:ENSP00000459391|ensembl:ENSP00000459532|ensembl:ENSP00000461700|uniprotkb:D3DSF3|uniprotkb:D3DSF4|uniprotkb:O14659|uniprotkb:A8KA32|uniprotkb:A8K945|uniprotkb:Q52M77	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pur2_human(display_long)|uniprotkb:GART(gene name)|psi-mi:GART(display_short)|uniprotkb:PRGS(gene name synonym)|uniprotkb:PGFT(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0046084"(adenine biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR004607(Phosphoribosylglycinamide formyltransferase)|interpro:IPR004733(Phosphoribosylformylglycinamidine cyclo-ligase)|interpro:IPR010918(AIR synthase related protein, C-terminal)|ensembl:ENST00000571089(transcript)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|ensembl:ENST00000573055(transcript)|ensembl:ENST00000575273(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0004637"(phosphoribosylamine-glycine ligase activity)|go:"GO:0004641"(phosphoribosylformylglycinamidine cyclo-ligase activity)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|go:"GO:0004644"(phosphoribosylglycinamide formyltransferase activity)|interpro:IPR016185(PreATP-grasp-like fold)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|interpro:IPR016188(PurM, N-terminal-like)|ensembl:ENSG00000159131(gene)|ensembl:ENSG00000262473(gene)|ensembl:ENST00000381815(transcript)|ensembl:ENST00000381831(transcript)|ensembl:ENST00000381839(transcript)|interpro:IPR020560|interpro:IPR020561|interpro:IPR020562|interpro:IPR036477|interpro:IPR036676|interpro:IPR036921|interpro:IPR037123|mint:P22102|rcsb pdb:1MEJ|rcsb pdb:1MEN|rcsb pdb:1MEO|rcsb pdb:1NJS|rcsb pdb:1RBM|rcsb pdb:1RBQ|rcsb pdb:1RBY|rcsb pdb:1RBZ|rcsb pdb:1RC0|rcsb pdb:1RC1|rcsb pdb:1ZLX|rcsb pdb:1ZLY|rcsb pdb:2QK4|rcsb pdb:2V9Y|rcsb pdb:4EW1|rcsb pdb:4EW2|rcsb pdb:4EW3|rcsb pdb:4ZYT|interpro:IPR020559|rcsb pdb:4ZYU|rcsb pdb:4ZYV|rcsb pdb:4ZYW|rcsb pdb:4ZYX|rcsb pdb:4ZYY|rcsb pdb:4ZYZ|rcsb pdb:4ZZ0|rcsb pdb:4ZZ1|rcsb pdb:4ZZ2|rcsb pdb:5J9F|rcsb pdb:7JG0|rcsb pdb:4ZZ3|refseq:NP_000810.1|refseq:NP_001129477.1|refseq:NP_001129478.1|refseq:NP_780294.1|rcsb pdb:7JG4|reactome:R-HSA-73817|rcsb pdb:7JG3|refseq:XP_011527828.1|refseq:XP_006724052.1|refseq:XP_006724053.1|refseq:XP_005260998.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:7Iy33CtBsB8LHZFDP5mZ3eRX8pU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P07900	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9UJS0	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1222503|uniprotkb:O14566|uniprotkb:O14575|uniprotkb:Q9NZW1|uniprotkb:Q9UNI7|uniprotkb:Q546F9|ensembl:ENSP00000265631	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cmc2_human(display_long)|uniprotkb:SLC25A13(gene name)|psi-mi:SLC25A13(display_short)|uniprotkb:ARALAR2(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_055066.1|refseq:NP_001153682.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9UJS0|rcsb pdb:4P5W|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693|ensembl:ENSG00000004864(gene)|ensembl:ENST00000265631(transcript)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:YtrKzkRujsJ/hzl2bJaLgJAAswI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P11940	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:XudTSPq2h9ckKAc48X88RVafPRU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O94776	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1783035|uniprotkb:Q68DB1|uniprotkb:Q9UQB5|ensembl:ENSP00000278823	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:mta2_human(display_long)|uniprotkb:MTA2(gene name)|psi-mi:MTA2(display_short)|uniprotkb:MTA1L1(gene name synonym)|uniprotkb:PID(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym)|uniprotkb:p53 target protein in deacetylase complex(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004730.2|refseq:NP_001317221.1|dip:DIP-46519N|ensembl:ENSG00000149480(gene)|ensembl:ENST00000278823(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:O94776|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:D4wOsdMJYhY/ltvcnnuMHqNrFkc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P41250	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-724143|uniprotkb:B3KQA2|uniprotkb:B4DIA0|ensembl:ENSP00000373918|uniprotkb:Q969Y1|intact:EBI-25629666|uniprotkb:A0A090N8G0	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:gars_human(display_long)|uniprotkb:GARS1(gene name)|psi-mi:GARS1(display_short)|uniprotkb:Diadenosine tetraphosphate synthetase(gene name synonym)|uniprotkb:GARS(gene name synonym)|uniprotkb:Glycyl-tRNA synthetase(gene name synonym)|uniprotkb:Glycyl-tRNA synthetase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002038.2|rcsb pdb:4KQE|rcsb pdb:4KR2|rcsb pdb:2ZT6|rcsb pdb:4KR3|rcsb pdb:4QEI|rcsb pdb:5E6M|reactome:R-HSA-379716|rcsb pdb:2ZT7|reactome:R-HSA-379726|rcsb pdb:2ZT8|rcsb pdb:2ZXF|ensembl:ENSG00000106105(gene)|ensembl:ENST00000389266(transcript)|go:"GO:0004081"("bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity")|go:"GO:0004820"(glycine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006426"(glycyl-tRNA aminoacylation)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0016740"(transferase activity)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070150"(mitochondrial glycyl-tRNA aminoacylation)|interpro:IPR000738(WHEP-TRS)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002315(Glycyl-tRNA synthetase, alpha2 dimer)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR027031|interpro:IPR033731|interpro:IPR036621|mint:P41250|rcsb pdb:2PME|rcsb pdb:2PMF|rcsb pdb:2Q5H|rcsb pdb:2Q5I|rcsb pdb:2ZT5|refseq:NP_001303701.1|dip:DIP-50471N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:bBlAPOMGXKsEvu0DxGKJJLjDI1s9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O15371	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-353818|uniprotkb:Q3MJD9|uniprotkb:Q5M9Q6|uniprotkb:B2R7D4|intact:EBI-10969985|ensembl:ENSP00000216190|ensembl:ENSP00000385812|uniprotkb:A8MWD3|uniprotkb:B4DTF8|uniprotkb:B4DVY1	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:eif3d_human(display_long)|uniprotkb:EIF3D(gene name)|psi-mi:EIF3D(display_short)|uniprotkb:EIF3S7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003744.1|ensembl:ENSG00000100353(gene)|ensembl:ENST00000216190(transcript)|ensembl:ENST00000405442(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O15371|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32870N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:hw2nyiDfdecEhLmKA5U9+46bBag9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q13620	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P78527	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q12907	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-3915406|uniprotkb:Q53HH1|ensembl:ENSP00000303366	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:lman2_human(display_long)|uniprotkb:LMAN2(gene name)|psi-mi:LMAN2(display_short)|uniprotkb:C5orf8(gene name synonym)|uniprotkb:Glycoprotein GP36b(gene name synonym)|uniprotkb:Lectin mannose-binding 2(gene name synonym)|uniprotkb:Vesicular integral-membrane protein 36(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006807.1|ensembl:ENSG00000169223(gene)|ensembl:ENST00000303127(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035664|mint:Q12907|reactome:R-HSA-204005|reactome:R-HSA-5694530	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:goqUZGW9/lvVMWDAZS9csH3TqWY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9NTK5	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-766468|uniprotkb:Q5BJD7|uniprotkb:Q8NCI8|uniprotkb:Q96CU1|uniprotkb:Q96SV2|uniprotkb:Q9P1D3|uniprotkb:Q9UNY9|uniprotkb:Q9Y6G4|uniprotkb:D7EHM2|ensembl:ENSP00000284719	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ola1_human(display_long)|uniprotkb:GTPBP9(gene name synonym)|uniprotkb:GTP-binding protein 9(gene name synonym)|uniprotkb:OLA1(gene name)|psi-mi:OLA1(display_short)|uniprotkb:PTD004(orf name)|uniprotkb:PRO2455(orf name)|uniprotkb:DNA damage-regulated overexpressed in cancer 45(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001011708.1|refseq:NP_037473.3|dip:DIP-34591N|ensembl:ENST00000284719(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004095(TGS)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR023192|interpro:IPR027417|interpro:IPR031167|interpro:IPR041706|mint:Q9NTK5|rcsb pdb:2OHF|reactome:R-HSA-114608|ensembl:ENSG00000138430(gene)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:aQk5XBcKpx1YSW4mHtyRsTpimvk9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P37268	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-714550|intact:EBI-1058542|uniprotkb:Q96GT0|ensembl:ENSP00000220584|ensembl:ENSP00000480828|ensembl:ENSP00000481481|uniprotkb:B3KQ95|uniprotkb:B4DJE5|uniprotkb:B4DT56|uniprotkb:B7Z1J3	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:fdft_human(display_long)|uniprotkb:Farnesyl-diphosphate farnesyltransferase(gene name synonym)|uniprotkb:"FPP:FPP farnesyltransferase"(gene name synonym)|uniprotkb:FDFT1(gene name)|psi-mi:FDFT1(display_short)|uniprotkb:Farnesyl-diphosphate farnesyltransferase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENST00000618539(transcript)|refseq:NP_004453.3|ensembl:ENSG00000079459(gene)|ensembl:ENST00000220584(transcript)|ensembl:ENST00000615631(transcript)|rcsb pdb:3LEE|rcsb pdb:3Q2Z|rcsb pdb:3Q30|rcsb pdb:3V66|rcsb pdb:3VJ8|rcsb pdb:3VJ9|rcsb pdb:3VJA|rcsb pdb:3VJB|rcsb pdb:3VJC|rcsb pdb:3WC9|rcsb pdb:3WCD|rcsb pdb:3WCF|rcsb pdb:3WCH|rcsb pdb:3WCI|rcsb pdb:3WCJ|rcsb pdb:3WCL|rcsb pdb:3WCM|rcsb pdb:3WEF|rcsb pdb:3WEG|rcsb pdb:3WEH|rcsb pdb:3WEI|rcsb pdb:3WEJ|rcsb pdb:3WEK|rcsb pdb:3WSA|rcsb pdb:6PYJ|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|rcsb pdb:3ASX|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0004310"(farnesyl-diphosphate farnesyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045338"(farnesyl diphosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051996"(squalene synthase activity)|interpro:IPR002060(Squalene/phytoene synthase)|interpro:IPR006449(Farnesyl-diphosphate farnesyltransferase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR019845|interpro:IPR033904|interpro:IPR044844|mint:P37268|rcsb pdb:1EZF|refseq:NP_001274671.1|refseq:NP_001274672.1|refseq:NP_001274673.1|refseq:NP_001274674.1|refseq:NP_001274676.1|refseq:NP_001274677.1|refseq:NP_001274678.1|refseq:NP_001274679.1|refseq:NP_001274680.1|refseq:NP_001274685.1|refseq:XP_016868706.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:3TjanjXw3X58/ZOEsB1xczV0/qQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q58FF6	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916503	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:h90b4_human(display_long)|uniprotkb:HSP90AB4P(gene name)|psi-mi:HSP90AB4P(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|interpro:IPR036890|interpro:IPR037196	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:QbdOQ7fRCkzGfLHJOXN+54+Qb/g9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q13310	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q07866	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-721019|uniprotkb:F8VTM4|uniprotkb:Q7RTQ3|uniprotkb:Q86V77|uniprotkb:Q86V78|uniprotkb:Q86V79|uniprotkb:Q7RTM2|uniprotkb:Q7RTM3|uniprotkb:Q7RTM5|uniprotkb:Q7RTP9|uniprotkb:Q7RTQ5|uniprotkb:Q7RTQ6|uniprotkb:Q86SF5|uniprotkb:Q86TF5|uniprotkb:Q86V74|uniprotkb:Q86V75|uniprotkb:Q86V76|uniprotkb:Q96H62|uniprotkb:A6NF62|intact:EBI-28976313|ensembl:ENSP00000341154	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:klc1_human(display_long)|uniprotkb:KLC1(gene name)|psi-mi:KLC1(display_short)|uniprotkb:KLC(gene name synonym)|uniprotkb:KNS2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001123579.1|refseq:NP_005543.2|refseq:NP_891553.2|ensembl:ENST00000452929|ensembl:ENSP00000414982|ensembl:ENST00000553286|ensembl:ENSP00000452487|ensembl:ENST00000246489|ensembl:ENSP00000246489|ensembl:ENST00000334553|ensembl:ENST00000554228|ensembl:ENSP00000450616|ensembl:ENST00000557450|ensembl:ENSP00000450648|ensembl:ENST00000634686|ensembl:ENSP00000488938|ensembl:ENSP00000334523|ensembl:ENST00000347839|ensembl:ENSP00000334618|ensembl:ENSP00000341154|ensembl:ENST00000389744|ensembl:ENSP00000374394|dip:DIP-40371N|ensembl:ENSG00000126214(gene)|ensembl:ENST00000348520(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035617"(stress granule disassembly)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:Q07866|rcsb pdb:3NF1|rcsb pdb:5OJ8|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|go:"GO:0030426"(growth cone)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:T7SJbB/PScRqj74O/NH4q1KU0YM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9Y6K9	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P62136	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P16615	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P21281	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-4290814|uniprotkb:Q14544|uniprotkb:Q15859|uniprotkb:B2R5Z3|uniprotkb:D3DSQ5|uniprotkb:Q96IR0|ensembl:ENSP00000276390	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:vatb2_human(display_long)|uniprotkb:ATP6V1B2(gene name)|psi-mi:ATP6V1B2(display_short)|uniprotkb:ATP6B2(gene name synonym)|uniprotkb:VPP3(gene name synonym)|uniprotkb:Endomembrane proton pump 58 kDa subunit(gene name synonym)|uniprotkb:HO57(gene name synonym)|uniprotkb:Vacuolar proton pump subunit B 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001684.2|ensembl:ENSG00000147416(gene)|ensembl:ENST00000276390(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR020003|interpro:IPR022879|interpro:IPR027417|mint:P21281|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|dip:DIP-47433N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:CikZS+29TqYLiADRWgVESqCpg689606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O00203	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1044383|ensembl:ENSP00000255194|uniprotkb:O00580|uniprotkb:Q7Z393|uniprotkb:Q9HD66|uniprotkb:E5RJ68|intact:EBI-10969499	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ap3b1_human(display_long)|uniprotkb:Adaptor protein complex AP-3 subunit beta-1(gene name synonym)|uniprotkb:Beta-3A-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta-1 large chain(gene name synonym)|uniprotkb:AP3B1(gene name)|psi-mi:AP3B1(display_short)|uniprotkb:ADTB3A(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0006464"(cellular protein modification process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007040"(lysosome organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016020"(membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032438"(melanosome organization)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0090152"(establishment of protein localization to mitochondrial membrane involved in mitochondrial fission)|go:"GO:0098773"(skin epidermis development)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|interpro:IPR029390|interpro:IPR029394|mint:O00203|reactome:R-HSA-432722|reactome:R-HSA-6802952|refseq:NP_003655.3|ensembl:ENSG00000132842(gene)|ensembl:ENST00000255194(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003016"(respiratory system process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|refseq:NP_001258698.1|dip:DIP-24208N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:+06UuQo62p9ALS7DiX+yKg7YRyg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P31689	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P22234	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9UI12	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-724719|uniprotkb:Q6PK44|uniprotkb:Q9H3E3|uniprotkb:Q9Y300|uniprotkb:B3KMR0|ensembl:ENSP00000352522|ensembl:ENSP00000379995	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:vath_human(display_long)|uniprotkb:Vacuolar proton pump subunit H(gene name synonym)|uniprotkb:V-ATPase 50/57 kDa subunits(gene name synonym)|uniprotkb:Vacuolar proton pump subunit SFD(gene name synonym)|uniprotkb:Protein VMA13 homolog(gene name synonym)|uniprotkb:Nef-binding protein 1(gene name synonym)|uniprotkb:ATP6V1H(gene name)|psi-mi:ATP6V1H(display_short)|uniprotkb:CGI-11(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_057025.2|refseq:NP_998784.1|refseq:NP_998785.1|ensembl:ENSG00000047249(gene)|ensembl:ENST00000359530(transcript)|ensembl:ENST00000396774(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004908(ATPase, V1 complex, subunit H)|interpro:IPR011987(ATPase, V1 complex, subunit H, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038497|mint:Q9UI12|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-167590|reactome:R-HSA-182218|reactome:R-HSA-917977|reactome:R-HSA-9636467|reactome:R-HSA-9639288|reactome:R-HSA-983712|reactome:R-HSA-77387|refseq:XP_006716518.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:n2fyA8m4qnlSmS3R1xBBE3RRV9A9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O75746	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1047585|uniprotkb:Q96AM8|intact:EBI-2802067|uniprotkb:B3KR64|ensembl:ENSP00000388658	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cmc1_human(display_long)|uniprotkb:SLC25A12(gene name)|psi-mi:SLC25A12(display_short)|uniprotkb:ARALAR1(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 12(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003696.2|ensembl:ENSG00000115840(gene)|ensembl:ENST00000422440(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0051592"(response to calcium ion)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR018247|interpro:IPR023395|mint:O75746|rcsb pdb:4P5X|rcsb pdb:4P60|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:NMohxjKtV1fhusocdkdQYZ/ng3I9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q58FG1	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916562	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:hs904_human(display_long)|uniprotkb:HSP90AA4P(gene name)|psi-mi:HSP90AA4P(display_short)|uniprotkb:HSP90AD(gene name synonym)|uniprotkb:HSPCAL2(gene name synonym)|uniprotkb:Heat shock 90 kDa protein 1 alpha-like 2(gene name synonym)|uniprotkb:Heat shock protein 90-alpha D(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|interpro:IPR036890|interpro:IPR037196	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:ikTrrPpUeO74Iq6mjoTSomMVqsg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:A6NNZ2	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6149104|ensembl:ENSP00000496713	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tbb8b_human(display_long)|uniprotkb:TUBB8B(gene name)|psi-mi:TUBB8B(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000173213(gene)|ensembl:ENST00000308911(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:ZnXdFJO1ou4waHhr2FQtj3RFb4g9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P35579	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P14868	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-358730|uniprotkb:Q2TNI3|uniprotkb:Q32Q69|uniprotkb:Q53HV4|uniprotkb:Q53YC5|uniprotkb:Q9BW52|uniprotkb:Q68CR9|uniprotkb:A8K3J2|uniprotkb:D3DP77|ensembl:ENSP00000264161	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sydc_human(display_long)|uniprotkb:DARS1(gene name)|psi-mi:DARS1(display_short)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 40 protein(gene name synonym)|uniprotkb:DARS(gene name synonym)|uniprotkb:PIG40(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001340.2|refseq:NP_001280241.1|ensembl:ENSG00000115866(gene)|ensembl:ENST00000264161(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0045202"(synapse)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004523(Aspartyl-tRNA synthetase, class IIb, archea/euk type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P14868|rcsb pdb:4J15|rcsb pdb:5Y6L|rcsb pdb:6IY6|reactome:R-HSA-2408522|reactome:R-HSA-379716	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Yzpil/THkSHGR/ixVyQbV3RZz/E9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q58FF8	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2961708	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:h90b2_human(display_long)|uniprotkb:HSP90AB2P(gene name)|psi-mi:HSP90AB2P(display_short)|uniprotkb:HSP90BB(gene name synonym)|uniprotkb:Heat shock protein 90-beta b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|interpro:IPR036890|interpro:IPR037196	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:SntF/u+V170yoKZScA9O/5BL3Ps9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9H361	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1055272|uniprotkb:Q8NHV0|uniprotkb:Q9H086|ensembl:ENSP00000281589	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pabp3_human(display_long)|uniprotkb:"Testis-specific poly(A)-binding protein"(gene name synonym)|uniprotkb:PABPC3(gene name)|psi-mi:PABPC3(display_short)|uniprotkb:PABP3(gene name synonym)|uniprotkb:PABPL3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_112241.2|ensembl:ENSG00000151846(gene)|ensembl:ENST00000281589(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q9H361|rcsb pdb:2D9P|rcsb pdb:4IVE	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:g/tDJDBcBC+s8P6LGDIwgZO8HHY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P55884	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-366696|uniprotkb:Q2NL77|uniprotkb:Q9UMF9|uniprotkb:A4D208|ensembl:ENSP00000354125|ensembl:ENSP00000380206	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:eif3b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:eIF-3-eta(gene name synonym)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:Prt1 homolog(gene name synonym)|uniprotkb:EIF3B(gene name)|psi-mi:EIF3B(display_short)|uniprotkb:EIF3S9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001032360.1|refseq:NP_003742.2|refseq:XP_011513901.1|refseq:XP_011513902.1|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|ensembl:ENSG00000106263(gene)|ensembl:ENST00000360876(transcript)|ensembl:ENST00000397011(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045202"(synapse)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|mint:P55884|rcsb pdb:2KRB|rcsb pdb:2NLW|rcsb pdb:5K1H|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:XP_016868241.1|dip:DIP-31113N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:MxQFPvmuOcO/S+4NqzToozWr8K89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q13619	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-456106|uniprotkb:O75834|uniprotkb:Q589T6|uniprotkb:Q5TC62|uniprotkb:Q6UP08|uniprotkb:Q9UP17|uniprotkb:A2A2W2|ensembl:ENSP00000364589	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cul4a_human(display_long)|uniprotkb:CUL4A(gene name)|psi-mi:CUL4A(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001008895.1|refseq:NP_003580.1|refseq:NP_001265442.1|refseq:XP_011535825.1|dip:DIP-31610N|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13619|rcsb pdb:2HYE|rcsb pdb:4A0K|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|ensembl:ENSG00000139842(gene)|ensembl:ENST00000375440(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:xYRRxjpO/9qqeXtq9dfACAdqyM89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P51570	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2269932|uniprotkb:B2RC07|intact:EBI-6190170|uniprotkb:B4E1G6|ensembl:ENSP00000225614|ensembl:ENSP00000465930	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:galk1_human(display_long)|uniprotkb:GALK1(gene name)|psi-mi:GALK1(display_short)|uniprotkb:GALK(gene name synonym)|uniprotkb:Galactose kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0019388"(galactose catabolic process)|go:"GO:0019402"(galactitol metabolic process)|go:"GO:0061623"(glycolytic process from galactose)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|mint:P51570|ensembl:ENSG00000108479(gene)|ensembl:ENST00000225614(transcript)|ensembl:ENST00000588479(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0016020"(membrane)|rcsb pdb:1WUU|rcsb pdb:1YH7|rcsb pdb:6GR2|rcsb pdb:6Q3W|rcsb pdb:6Q3X|rcsb pdb:6Q8Z|rcsb pdb:6Q90|rcsb pdb:6Q91|rcsb pdb:6QJE|rcsb pdb:6ZFH|rcsb pdb:6ZGV|rcsb pdb:6ZGW|rcsb pdb:6ZGX|rcsb pdb:6ZGY|rcsb pdb:6ZGZ|reactome:R-HSA-5609976|reactome:R-HSA-70370	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:TtFcTQq+nspsst+xInA/huo/ZbU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q8NF37	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-922595|uniprotkb:Q1HAQ1|uniprotkb:Q7Z4G6|uniprotkb:Q8N3U7|uniprotkb:Q8WUL8|uniprotkb:Q9GZW6|ensembl:ENSP00000283415|ensembl:ENSP00000423472	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pcat1_human(display_long)|uniprotkb:1-alkylglycerophosphocholine O-acetyltransferase(gene name synonym)|uniprotkb:Acyltransferase-like 2(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 3(gene name synonym)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase(gene name synonym)|uniprotkb:1-alkenylglycerophosphocholine O-acyltransferase(gene name synonym)|uniprotkb:LPCAT1(gene name)|psi-mi:LPCAT1(display_short)|uniprotkb:AYTL2(gene name synonym)|uniprotkb:PFAAP3(gene name synonym)|uniprotkb:"Acetyl-CoA:lyso-platelet-activating factor acetyltransferase"(gene name synonym)|uniprotkb:1-acylglycerophosphocholine O-acyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_079106.3|ensembl:ENSG00000153395(gene)|ensembl:ENST00000283415(transcript)|ensembl:ENST00000475622(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0036148"(phosphatidylglycerol acyl-chain remodeling)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047144"(2-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0047159"(1-alkenylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047191"(1-alkylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047192"(1-alkylglycerophosphocholine O-acetyltransferase activity)|go:"GO:0050200"(plasmalogen synthase activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2001246"(negative regulation of phosphatidylcholine biosynthetic process)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR011992(EF-Hand type)|reactome:R-HSA-1482788|reactome:R-HSA-1482925|reactome:R-HSA-1483166|reactome:R-HSA-1483191|reactome:R-HSA-6798695	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:sJPdIAauFmV71N/KwIUH75hTHv09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P63151	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:evS6klM2alZXtMthVsshKkrNgiA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P42704	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P08559	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-715747|uniprotkb:Q9NP12|uniprotkb:Q9UBJ8|uniprotkb:Q9UBU0|uniprotkb:Q9UNG4|uniprotkb:Q9UNG5|uniprotkb:Q5JPT8|uniprotkb:Q53H41|uniprotkb:B2R5P7|uniprotkb:B7Z3T7|uniprotkb:B7Z3X5|uniprotkb:A5YVE9|ensembl:ENSP00000394382	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:odpa_human(display_long)|uniprotkb:PDHE1-A type I(gene name synonym)|uniprotkb:PDHA1(gene name)|psi-mi:PDHA1(display_short)|uniprotkb:PHE1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001166926.1|refseq:NP_001166927.1|refseq:NP_000275.1|refseq:NP_001166925.1|ensembl:ENSG00000131828(gene)|ensembl:ENST00000422285(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017597("Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y")|interpro:IPR029061|rcsb pdb:1NI4|rcsb pdb:2OZL|rcsb pdb:3EXE|rcsb pdb:3EXF|rcsb pdb:3EXG|rcsb pdb:3EXH|rcsb pdb:3EXI|rcsb pdb:6CER|rcsb pdb:6CFO|reactome:R-HSA-204174|reactome:R-HSA-389661|reactome:R-HSA-5362517|reactome:R-HSA-70268|dip:DIP-37652N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:p4PObFZ4cxJW6ICug+jhlgKlEYY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q16378	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-738624|uniprotkb:Q8NFB3|uniprotkb:A8KA69|uniprotkb:F5H0D7|ensembl:ENSP00000228811|ensembl:ENSP00000459468|ensembl:ENSP00000477689	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:prol4_human(display_long)|uniprotkb:PRR4(gene name)|psi-mi:PRR4(display_short)|uniprotkb:LPRP(gene name synonym)|uniprotkb:PROL4(gene name synonym)|uniprotkb:Lacrimal proline-rich protein(gene name synonym)|uniprotkb:Nasopharyngeal carcinoma-associated proline-rich protein 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001092008.2|refseq:NP_009175.2|ensembl:ENSG00000111215(gene)|ensembl:ENSG00000263247(gene)|ensembl:ENSG00000282269(gene)|ensembl:ENST00000228811(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0007601"(visual perception)|interpro:IPR026086|mint:Q16378|ensembl:ENST00000574424(transcript)|ensembl:ENST00000614435(transcript)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:wkkslTDK+a/17dqz+iL0yadicwY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P63010	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-432924|uniprotkb:A6NJP3|uniprotkb:P21851|uniprotkb:Q96J19|intact:EBI-28970775|ensembl:ENSP00000482315|intact:EBI-8011909|intact:MINT-8395045|uniprotkb:Q7Z451	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ap2b1_human(display_long)|uniprotkb:AP2B1(gene name)|psi-mi:AP2B1(display_short)|uniprotkb:CLAPB1(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:ADTB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001025177.1|refseq:NP_001273.1|ensembl:ENST00000610402|ensembl:ENSP00000483185|ensembl:ENST00000618940|ensembl:ENSP00000482835|ensembl:ENSP00000482315|go:"GO:0005048"(signal sequence binding)|go:"GO:0005829"(cytosol)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR000225(Armadillo)|ensembl:ENSG00000006125(gene)|ensembl:ENST00000621914(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003281"(ventricular septum development)|refseq:XP_011522757.1|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0035904"(aorta development)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0005886"(plasma membrane)|refseq:XP_005257994.1|refseq:XP_005257995.1|refseq:XP_016879773.1|refseq:XP_016879775.1|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|rcsb pdb:1E42|rcsb pdb:2G30|rcsb pdb:2IV8|rcsb pdb:2IV9|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VGL|rcsb pdb:2XA7|rcsb pdb:4UQI|rcsb pdb:5M5R|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6QH7|rcsb pdb:6URI|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|rcsb pdb:6YAI|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|dip:DIP-33098N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Q5oFhdE1hcmqu7xLG3MteCu0Zcg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q01814	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1174243|uniprotkb:O00766|uniprotkb:Q12994|uniprotkb:Q16818|ensembl:ENSP00000353414|ensembl:ENSP00000494716	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:at2b2_human(display_long)|uniprotkb:ATP2B2(gene name)|psi-mi:ATP2B2(display_short)|uniprotkb:PMCA2(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 2(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001001331.1|refseq:XP_005265236.1|refseq:XP_011532054.1|refseq:XP_006713238.1|ensembl:ENSG00000157087(gene)|ensembl:ENST00000360273(transcript)|ensembl:ENST00000645850(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1905059"(P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030322|interpro:IPR036412|interpro:IPR044492|mint:Q01814|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_001317540.1|refseq:XP_016861970.1|refseq:XP_016861971.1|refseq:XP_016861972.1|refseq:XP_016861973.1|refseq:XP_016861975.1|refseq:XP_016861978.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:bCD7j13UJUgWoSHShHLKJBiVGJM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q12840	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-713468|uniprotkb:Q4LE26|ensembl:ENSP00000408979|uniprotkb:A6H8M5	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:kif5a_human(display_long)|uniprotkb:Neuronal kinesin heavy chain(gene name synonym)|uniprotkb:Kinesin heavy chain neuron-specific 1(gene name synonym)|uniprotkb:KIF5A(gene name)|psi-mi:KIF5A(display_short)|uniprotkb:NKHC1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENST00000455537(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q12840|rcsb pdb:4UXT|rcsb pdb:4UXY|rcsb pdb:4UY0|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|ensembl:ENSG00000155980(gene)|refseq:NP_004975.2|dip:DIP-37584N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:fvhe2vZFe1vN8SS4IPCMA5Nr7j09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q13200	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:A8MTJ3	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2562716|uniprotkb:B9EJG5|uniprotkb:A4D1B3|uniprotkb:A4D1B2|ensembl:ENSP00000381339	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:gnat3_human(display_long)|uniprotkb:GNAT3(gene name)|psi-mi:GNAT3(display_short)|uniprotkb:Gustducin alpha-3 chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001095856.1|ensembl:ENSG00000214415(gene)|ensembl:ENST00000398291(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0046872"(metal ion binding)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-HSA-170670|reactome:R-HSA-381771|reactome:R-HSA-392170|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-9009391|reactome:R-HSA-9660821	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:cOrLHKxFrfls1U5hJnzva77E2CY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P48735	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-3931130|uniprotkb:Q96GT3|uniprotkb:B2R6L6|ensembl:ENSP00000331897|uniprotkb:B4DFL2	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:idhp_human(display_long)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:ICD-M(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000182054(gene)|ensembl:ENST00000330062(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:P48735|rcsb pdb:4JA8|rcsb pdb:5GIS|rcsb pdb:5I95|rcsb pdb:5I96|rcsb pdb:5SVN|rcsb pdb:5SVO|rcsb pdb:6ADI|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VFZ|reactome:R-HSA-2151201|reactome:R-HSA-71403|refseq:NP_002159.2|refseq:NP_001276839.1|refseq:NP_001277043.1|dip:DIP-61416N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:CeuTM4HmOk3+OKkWlOt9JfNlCIM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9BZQ8	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916466|ensembl:ENSP00000356481|uniprotkb:Q2TTR2|uniprotkb:Q5TEM8|uniprotkb:Q8TEI5|uniprotkb:Q9H593|uniprotkb:Q9H9Y8|uniprotkb:Q9HCB9	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:niba1_human(display_long)|uniprotkb:NIBAN1(gene name)|psi-mi:NIBAN1(display_short)|uniprotkb:C1orf24(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 39 protein(gene name synonym)|uniprotkb:FAM129A(gene name synonym)|uniprotkb:NIBAN(gene name synonym)|uniprotkb:Protein FAM129A(gene name synonym)|uniprotkb:GIG39(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000135842(gene)|ensembl:ENST00000367511(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026088|go:"GO:0001933"(negative regulation of protein phosphorylation)|refseq:NP_443198.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:eCwv2j3CX9GWsxpQ26le50jOjAE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9UGP8	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1045560|uniprotkb:O95380|uniprotkb:Q5THN4|uniprotkb:Q86VS9|uniprotkb:Q8IWL0|uniprotkb:Q9NTE0|ensembl:ENSP00000357998	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sec63_human(display_long)|uniprotkb:SEC63(gene name)|psi-mi:SEC63(display_short)|uniprotkb:SEC63L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000025796(gene)|ensembl:ENST00000369002(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031207"(Sec62/Sec63 complex)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004179(Sec63)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027137|interpro:IPR035892|interpro:IPR036869|refseq:NP_009145.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:QXVh3v6bLcCJJxrLPU5drIj1K2c9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q14651	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1047196|uniprotkb:D3DNG3|uniprotkb:A8K2Q1|uniprotkb:Q8NEG6|ensembl:ENSP00000336831|ensembl:ENSP00000387890|ensembl:ENSP00000418700	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:plsi_human(display_long)|uniprotkb:Intestine-specific plastin(gene name synonym)|uniprotkb:PLS1(gene name)|psi-mi:PLS1(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR018247|interpro:IPR011992(EF-Hand type)|interpro:IPR030235|interpro:IPR036872|interpro:IPR039959|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_001138791.1|refseq:NP_001165783.1|refseq:NP_002661.2|refseq:XP_011511202.1|refseq:XP_011511203.1|refseq:XP_011511205.1|ensembl:ENSG00000120756(gene)|ensembl:ENST00000337777(transcript)|ensembl:ENST00000457734(transcript)|ensembl:ENST00000497002(transcript)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005903"(brush border)|go:"GO:0032420"(stereocilium)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060121"(vestibular receptor cell stereocilium organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990357"(terminal web)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|refseq:XP_006713723.1|refseq:XP_016862115.1|refseq:XP_016862116.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:jDBbZOh8WmNZbAhnOmxcqb6fGvc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P63267	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q02809	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357174|ensembl:ENSP00000196061|uniprotkb:Q96AV9|uniprotkb:Q9H132|uniprotkb:B4DR87|intact:EBI-21357524	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:plod1_human(display_long)|uniprotkb:PLOD(gene name synonym)|uniprotkb:PLOD1(gene name)|psi-mi:PLOD1(display_short)|uniprotkb:LLH(gene name synonym)|uniprotkb:Lysyl hydroxylase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000083444(gene)|ensembl:ENST00000196061(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0008544"(epidermis development)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902494"(catalytic complex)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:Q02809|reactome:R-HSA-1650814|refseq:NP_000293.2|refseq:NP_001303249.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:q0eJHb8L3qTbN1PnjQ8L0PcpOLw9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O75175	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-743073|ensembl:ENSP00000221232|ensembl:ENSP00000351159|ensembl:ENSP00000478280|ensembl:ENSP00000478956|ensembl:ENSP00000479987|ensembl:ENSP00000480258|ensembl:ENSP00000480585|ensembl:ENSP00000480697|ensembl:ENSP00000480876|ensembl:ENSP00000480988|ensembl:ENSP00000481681|ensembl:ENSP00000481924|ensembl:ENSP00000483036|ensembl:ENSP00000483431|ensembl:ENSP00000483604|ensembl:ENSP00000483692|ensembl:ENSP00000483882|ensembl:ENSP00000483968|ensembl:ENSP00000484040|ensembl:ENSP00000484794|uniprotkb:Q9NZN7|uniprotkb:Q9UF76|intact:EBI-6504867	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cnot3_human(display_long)|uniprotkb:CCR4-associated factor 3(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 2(gene name synonym)|uniprotkb:CNOT3(gene name)|psi-mi:CNOT3(display_short)|uniprotkb:KIAA0691(gene name synonym)|uniprotkb:NOT3(gene name synonym)|uniprotkb:LENG2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000088038(gene)|ensembl:ENSG00000273943(gene)|ensembl:ENSG00000274176(gene)|ensembl:ENSG00000274616(gene)|ensembl:ENSG00000274941(gene)|ensembl:ENSG00000275979(gene)|ensembl:ENSG00000276082(gene)|ensembl:ENSG00000277114(gene)|ensembl:ENSG00000277600(gene)|ensembl:ENSG00000277615(gene)|ensembl:ENST00000221232(transcript)|ensembl:ENST00000358389(transcript)|ensembl:ENST00000610883(transcript)|ensembl:ENST00000611252(transcript)|ensembl:ENST00000612924(transcript)|ensembl:ENST00000613528(transcript)|ensembl:ENST00000613752(transcript)|ensembl:ENST00000614649(transcript)|ensembl:ENST00000615030(transcript)|ensembl:ENST00000616359(transcript)|ensembl:ENST00000616910(transcript)|ensembl:ENST00000617982(transcript)|ensembl:ENST00000618405(transcript)|ensembl:ENST00000619567(transcript)|ensembl:ENST00000619854(transcript)|ensembl:ENST00000620060(transcript)|ensembl:ENST00000620419(transcript)|ensembl:ENST00000620573(transcript)|ensembl:ENST00000620970(transcript)|ensembl:ENST00000622131(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|mint:O75175|rcsb pdb:4C0D|rcsb pdb:4C0G|rcsb pdb:5FU6|rcsb pdb:5FU7|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_055331.1|dip:DIP-40297N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Qm4YvclCLIfpgmygrSHtkxn/H9E9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O15372	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-709735|ensembl:ENSP00000429931	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003747.1|ensembl:ENSG00000147677(gene)|ensembl:ENST00000521861(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:O15372|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-33689N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q12996	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1056775|uniprotkb:Q32P22|uniprotkb:Q96FQ8|uniprotkb:Q96QD6|uniprotkb:E9PB40|uniprotkb:A8K471|uniprotkb:D3DR04|uniprotkb:Q96QK4|ensembl:ENSP00000315791	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cstf3_human(display_long)|uniprotkb:CSTF3(gene name)|psi-mi:CSTF3(display_short)|uniprotkb:CF-1 77 kDa subunit(gene name synonym)|uniprotkb:Cleavage stimulation factor 77 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001317.1|refseq:NP_001028677.1|refseq:NP_001028678.1|ensembl:ENSG00000176102(gene)|ensembl:ENST00000323959(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0031123"(RNA 3'-end processing)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008847(Suppressor of forked)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:6B3X|rcsb pdb:6URO|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-48674N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:B6WHmPlQvL07k0cOxithA+x6xKY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9H0Q0	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916407|uniprotkb:B3KNZ1|uniprotkb:Q53QW2|ensembl:ENSP00000370724|ensembl:ENSP00000384771	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cyria_human(display_long)|uniprotkb:CYRIA(gene name)|psi-mi:CYRIA(display_short)|uniprotkb:FAM49A(gene name synonym)|uniprotkb:Protein CYRIA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000197872(gene)|ensembl:ENST00000381323(transcript)|ensembl:ENST00000406434(transcript)|go:"GO:0016020"(membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|interpro:IPR009828(Protein of unknown function DUF1394)|interpro:IPR039789|refseq:XP_006712171.1|refseq:NP_110424.1|refseq:XP_005262687.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:HGaoDXY4qi/AZMdrg/aQBCKJoKI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P49915	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1050289|uniprotkb:A8K639|uniprotkb:B4DXV7|uniprotkb:F8W720|ensembl:ENSP00000419851	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:guaa_human(display_long)|uniprotkb:GMP synthetase(gene name synonym)|uniprotkb:Glutamine amidotransferase(gene name synonym)|uniprotkb:GMPS(gene name)|psi-mi:GMPS(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003866.1|ensembl:ENSG00000163655(gene)|ensembl:ENST00000496455(transcript)|go:"GO:0003921"(GMP synthase activity)|go:"GO:0003922"("GMP synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0016462"(pyrophosphatase activity)|interpro:IPR001674(GMP synthase, C-terminal)|interpro:IPR004739(GMP synthase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017926|interpro:IPR022310|interpro:IPR025777|interpro:IPR029062|mint:P49915|rcsb pdb:2VPI|rcsb pdb:2VXO|reactome:R-HSA-73817	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:LYs65bPoqjVG/ZxA6v+yJo3HsLI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P20645	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2907262|ensembl:ENSP00000000412|uniprotkb:A8K528|uniprotkb:D3DUV5	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:mprd_human(display_long)|uniprotkb:M6PR(gene name)|psi-mi:M6PR(display_short)|uniprotkb:MPR46(gene name synonym)|uniprotkb:MPRD(gene name synonym)|uniprotkb:46 kDa mannose 6-phosphate receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000003056(gene)|ensembl:ENST00000000412(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007041"(lysosomal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000296(Cation-dependent mannose-6-phosphate receptor)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR028927|interpro:IPR044865|mint:P20645|rcsb pdb:1JUQ|reactome:R-HSA-432720|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|refseq:NP_002346.1|refseq:XP_005253433.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Nx1pgku9M1SjHH42s5ZAY7c7eDc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P49589	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2691328|uniprotkb:Q53XI8|uniprotkb:Q9HD24|uniprotkb:Q9HD25|uniprotkb:Q5HYE4|ensembl:ENSP00000380300|ensembl:ENSP00000488657	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sycc_human(display_long)|uniprotkb:CARS1(gene name)|psi-mi:CARS1(display_short)|uniprotkb:CARS(gene name synonym)|uniprotkb:Cysteinyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001742.1|refseq:NP_644802.1|refseq:NP_001014437.1|ensembl:ENSG00000110619(gene)|ensembl:ENSG00000278191(gene)|ensembl:ENST00000397111(transcript)|ensembl:ENST00000633248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004817"(cysteine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006423"(cysteinyl-tRNA aminoacylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR015803(Cysteinyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR024909|interpro:IPR032678|reactome:R-HSA-379716	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:x6XOxU90AlAudm/b3atmp4xahZE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P78371	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9Y3L3	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-346869|uniprotkb:Q5R3N0|uniprotkb:Q6IBZ2|uniprotkb:Q6ZVL9|uniprotkb:Q96HQ5|uniprotkb:Q9NSQ9|ensembl:ENSP00000497104	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:3bp1_human(display_long)|uniprotkb:SH3BP1(gene name)|psi-mi:SH3BP1(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_061830.3|ensembl:ENSG00000100092(gene)|ensembl:ENST00000649765(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030834"(regulation of actin filament depolymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043535"(regulation of blood vessel endothelial cell migration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|interpro:IPR000198(RhoGAP)|interpro:IPR004148(BAR)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|mint:Q9Y3L3|rcsb pdb:4J9D|rcsb pdb:4J9F|reactome:R-HSA-9013149	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:FLnCGJhsS+syrKyjVQG4Q6UcZeU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q8TDW0	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916516|ensembl:ENSP00000359483|uniprotkb:B3KXS9|uniprotkb:Q29RV6|uniprotkb:Q9H075	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:lrc8c_human(display_long)|uniprotkb:LRRC8C(gene name)|psi-mi:LRRC8C(display_short)|uniprotkb:AD158(gene name synonym)|uniprotkb:FAD158(gene name synonym)|uniprotkb:Factor for adipocyte differentiation 158(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011540584.1|refseq:XP_016857992.1|ensembl:ENSG00000171488(gene)|ensembl:ENST00000370454(transcript)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR026906|interpro:IPR032675|reactome:R-HSA-5223345|refseq:NP_115646.2|dip:DIP-61362N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:NFBpNm8lOZCjVt4H1a4CW91G3rU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P11177	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1035872|uniprotkb:B2R7L0|uniprotkb:Q6FH45|uniprotkb:Q9BQ27|uniprotkb:Q9UFK3|ensembl:ENSP00000307241|uniprotkb:B4DDD7	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:odpb_human(display_long)|uniprotkb:PDHB(gene name)|psi-mi:PDHB(display_short)|uniprotkb:PHE1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000168291(gene)|ensembl:ENST00000302746(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR027110|interpro:IPR029061|interpro:IPR033248|mint:P11177|rcsb pdb:1NI4|rcsb pdb:2OZL|rcsb pdb:3EXE|rcsb pdb:3EXF|rcsb pdb:3EXG|rcsb pdb:3EXH|rcsb pdb:3EXI|rcsb pdb:6CER|rcsb pdb:6CFO|reactome:R-HSA-204174|reactome:R-HSA-389661|reactome:R-HSA-5362517|reactome:R-HSA-70268|refseq:NP_000916.2|refseq:NP_001166939.1|refseq:NP_001302465.1|dip:DIP-37651N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:VnabVXgFi4b43Wl37PzUX3+j4A89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q92945	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1049099|uniprotkb:O00301|uniprotkb:Q59EZ9|uniprotkb:Q5U4P6|uniprotkb:Q9UNT5|uniprotkb:Q9UQH5|intact:EBI-5455671|ensembl:ENSP00000381216	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:fubp2_human(display_long)|uniprotkb:KH type-splicing regulatory protein(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:KHSRP(gene name)|psi-mi:KHSRP(display_short)|uniprotkb:FUBP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003676.2|ensembl:ENSG00000088247(gene)|ensembl:ENST00000398148(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0051028"(mRNA transport)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q92945|rcsb pdb:2HH2|rcsb pdb:2HH3|rcsb pdb:2JVZ|rcsb pdb:2OPU|rcsb pdb:2OPV|rcsb pdb:4B8T|reactome:R-HSA-380994|reactome:R-HSA-450604|dip:DIP-48484N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:hlybJllTqSgPgtwwz3kc12zDYh49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q7L5N7	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-4280011|uniprotkb:A3KBM1|uniprotkb:Q6MZJ6|uniprotkb:Q9NX23|ensembl:ENSP00000262134	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pcat2_human(display_long)|uniprotkb:LPCAT2(gene name)|psi-mi:LPCAT2(display_short)|uniprotkb:AYTL1(gene name synonym)|uniprotkb:1-acylglycerophosphocholine O-acyltransferase(gene name synonym)|uniprotkb:1-alkylglycerophosphocholine O-acetyltransferase(gene name synonym)|uniprotkb:"Acetyl-CoA:lyso-platelet-activating factor acetyltransferase"(gene name synonym)|uniprotkb:Acyltransferase-like 1(gene name synonym)|uniprotkb:1-alkenylglycerophosphocholine O-acyltransferase(gene name synonym)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 11(gene name synonym)|uniprotkb:AGPAT11(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011521471.1|refseq:NP_060309.2|go:"GO:0047159"(1-alkenylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047192"(1-alkylglycerophosphocholine O-acetyltransferase activity)|go:"GO:0050200"(plasmalogen synthase activity)|go:"GO:0061024"(membrane organization)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|reactome:R-HSA-1482788|ensembl:ENSG00000087253(gene)|ensembl:ENST00000262134(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0047144"(2-acylglycerol-3-phosphate O-acyltransferase activity)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:7kcizNpGgOtfpMwKgx9kv6Hn7+s9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q10567	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1171303|uniprotkb:P78436|uniprotkb:C9JRD1|uniprotkb:Q20WL3|intact:EBI-11577132|uniprotkb:F8WDL0|uniprotkb:Q86X54|ensembl:ENSP00000319361|ensembl:ENSP00000350199|ensembl:ENSP00000384194|ensembl:ENSP00000400065	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ap1b1_human(display_long)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001118.3|refseq:NP_663782.2|refseq:NP_001159491.1|ensembl:ENSG00000100280(gene)|ensembl:ENST00000317368(transcript)|ensembl:ENST00000357586(transcript)|ensembl:ENST00000405198(transcript)|ensembl:ENST00000432560(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q10567|rcsb pdb:4HMY|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|rcsb pdb:6CRI|dip:DIP-24207N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:D0i+5PXwzbBmOSyeCOSFKZx8fQk9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P20020	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-5279998|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|ensembl:ENSP00000261173|ensembl:ENSP00000392043	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011536709.1|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_016874847.1|reactome:R-HSA-9662360|ensembl:ENSG00000070961(gene)|ensembl:ENST00000261173(transcript)|ensembl:ENST00000428670(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009409"(response to cold)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030320|interpro:IPR036412|interpro:IPR044492|mint:P20020|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990034"(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:kCpUNLYDF38hciXj32D8rXbXULg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P62333	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O60282	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-717170|uniprotkb:O95079|uniprotkb:Q2YDC5|ensembl:ENSP00000393379|ensembl:ENSP00000503013	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:kif5c_human(display_long)|uniprotkb:Kinesin heavy chain neuron-specific 2(gene name synonym)|uniprotkb:KIF5C(gene name)|psi-mi:KIF5C(display_short)|uniprotkb:KIAA0531(gene name synonym)|uniprotkb:NKHC2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004513.1|refseq:XP_011509459.1|refseq:XP_016859551.1|ensembl:ENSG00000168280(gene)|ensembl:ENST00000435030(transcript)|ensembl:ENST00000677891(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006996"(organelle organization)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0150034"(distal axon)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|mint:O60282|reactome:R-HSA-264876|interpro:IPR036961	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:4TqyBBhm1/nyaCSyz66oisPiwpA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q96CX2	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-358358|ensembl:ENSP00000366694	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:kcd12_human(display_long)|uniprotkb:KCTD12(gene name)|psi-mi:KCTD12(display_short)|uniprotkb:C13orf2(gene name synonym)|uniprotkb:KIAA1778(gene name synonym)|uniprotkb:PFET1(gene name synonym)|uniprotkb:Pfetin(gene name synonym)|uniprotkb:Predominantly fetal expressed T1 domain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_612453.1|ensembl:ENSG00000178695(gene)|ensembl:ENST00000377474(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q96CX2|rcsb pdb:6M8S|rcsb pdb:6QZL	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Xxp3in+fgJzZXJaorHFWXTbyKKQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q92542	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-998440|uniprotkb:Q86VV5|uniprotkb:Q5T207|ensembl:ENSP00000294785|uniprotkb:Q5T208	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:nica_human(display_long)|uniprotkb:NCSTN(gene name)|psi-mi:NCSTN(display_short)|uniprotkb:KIAA0253(gene name synonym)|uniprotkb:UNQ1874/PRO4317(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:6LR4|rcsb pdb:7C9I|rcsb pdb:7D8X|reactome:R-HSA-1251985|reactome:R-HSA-1474228|reactome:R-HSA-193692|reactome:R-HSA-205043|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3928665|reactome:R-HSA-6798695|reactome:R-HSA-9013507|reactome:R-HSA-9013700|reactome:R-HSA-9017802|rcsb pdb:6LQG|reactome:R-HSA-977225|ensembl:ENSG00000162736(gene)|ensembl:ENST00000294785(transcript)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0007611"(learning or memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0021549"(cerebellum development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042500"(aspartic endopeptidase activity, intramembrane cleaving)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0042983"(amyloid precursor protein biosynthetic process)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1990926"(short-term synaptic potentiation)|interpro:IPR008710(Nicastrin)|interpro:IPR041084|mint:Q92542|rcsb pdb:2N7Q|rcsb pdb:2N7R|rcsb pdb:4UIS|rcsb pdb:5A63|rcsb pdb:5FN2|rcsb pdb:5FN3|rcsb pdb:5FN4|rcsb pdb:5FN5|rcsb pdb:6IDF|rcsb pdb:6IYC|refseq:NP_056146.1|refseq:NP_001277113.1|refseq:NP_001277115.1|dip:DIP-36336N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Lf6xGDVDkOQXMUuG3Yn0tayAjF89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O43242	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O75874	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-715695|uniprotkb:Q567U4|uniprotkb:Q6FHQ6|uniprotkb:Q7Z3V0|uniprotkb:Q93090|uniprotkb:Q9NTJ9|uniprotkb:Q9UKW8|ensembl:ENSP00000260985|ensembl:ENSP00000390265|ensembl:ENSP00000410513	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:idhc_human(display_long)|uniprotkb:Cytosolic NADP-isocitrate dehydrogenase(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:PICD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005887.2|refseq:NP_001269315.1|refseq:NP_001269316.1|ensembl:ENSG00000138413(gene)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:1T09|rcsb pdb:1T0L|rcsb pdb:3INM|rcsb pdb:3MAP|rcsb pdb:3MAR|rcsb pdb:3MAS|rcsb pdb:4I3K|go:"GO:0060696"(regulation of phospholipid catabolic process)|rcsb pdb:4I3L|rcsb pdb:4KZO|rcsb pdb:4L03|rcsb pdb:4L04|rcsb pdb:4L06|rcsb pdb:4UMX|rcsb pdb:4UMY|rcsb pdb:4XRX|rcsb pdb:4XS3|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008585"(female gonad development)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000345146(transcript)|go:"GO:0045296"(cadherin binding)|ensembl:ENST00000415913(transcript)|ensembl:ENST00000446179(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|rcsb pdb:5DE1|rcsb pdb:5GIR|rcsb pdb:5K10|rcsb pdb:5K11|rcsb pdb:5L57|rcsb pdb:5L58|rcsb pdb:5LGE|rcsb pdb:5SUN|rcsb pdb:5SVF|rcsb pdb:5TQH|rcsb pdb:5YFM|rcsb pdb:5YFN|rcsb pdb:6ADG|rcsb pdb:6B0Z|rcsb pdb:6BKX|rcsb pdb:6BKY|rcsb pdb:6BKZ|rcsb pdb:6BL0|rcsb pdb:6BL1|rcsb pdb:6BL2|rcsb pdb:6IO0|rcsb pdb:6VEI|rcsb pdb:6VG0|reactome:R-HSA-389542|reactome:R-HSA-6798695|reactome:R-HSA-2978092|rcsb pdb:6O2Y|rcsb pdb:6O2Z|rcsb pdb:6PAY|rcsb pdb:6Q6F|rcsb pdb:6U4J|reactome:R-HSA-9033241|dip:DIP-59311N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:RFBziMEb70PKCzUCJm2jd40y44M9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P13796	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-698036|uniprotkb:Q5TBN4|uniprotkb:B2R613|uniprotkb:B4DUA0|ensembl:ENSP00000315757|ensembl:ENSP00000381581	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:plsl_human(display_long)|uniprotkb:L-plastin(gene name synonym)|uniprotkb:Lymphocyte cytosolic protein 1(gene name synonym)|uniprotkb:LC64P(gene name synonym)|uniprotkb:LCP1(gene name)|psi-mi:LCP1(display_short)|uniprotkb:PLS2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002289.2|refseq:XP_005266431.1|dip:DIP-34767N|ensembl:ENSG00000136167(gene)|ensembl:ENST00000323076(transcript)|ensembl:ENST00000398576(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002102"(podosome)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051639"(actin filament network formation)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|rcsb pdb:2D85|rcsb pdb:5JOJ|rcsb pdb:5JOL|reactome:R-HSA-8950505	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:1uy1zhroB3GHUiAwLjEdP5Rz1xM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q5JWF2	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-4400880|uniprotkb:A2A2S3|uniprotkb:E1P5G3|uniprotkb:O75684|uniprotkb:O75685|uniprotkb:Q5JW67|uniprotkb:Q5JWF1|uniprotkb:Q9NY42|ensembl:ENSP00000360141	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:gnas1_human(display_long)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:Extra large alphas protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001296812.1|refseq:NP_536350.2|refseq:XP_016883302.1|ensembl:ENSG00000087460(gene)|ensembl:ENST00000371100(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007606"(sensory perception of chemical stimulus)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048589"(developmental growth)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0060348"(bone development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:Q5JWF2|reactome:R-HSA-163359|reactome:R-HSA-164378|reactome:R-HSA-381676|reactome:R-HSA-392851|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9660821	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:UmsO2DSEM3LmGMPwxSdkmlrKMLc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q6NUK1	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-4289949|uniprotkb:Q705K4|uniprotkb:B7ZAI9|uniprotkb:Q5T331|uniprotkb:Q9P129|uniprotkb:Q5T485|uniprotkb:Q6PJJ9|ensembl:ENSP00000457733|ensembl:ENSP00000491572	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:scmc1_human(display_long)|uniprotkb:SLC25A24(gene name)|psi-mi:SLC25A24(display_short)|uniprotkb:APC1(gene name synonym)|uniprotkb:MCSC1(gene name synonym)|uniprotkb:SCAMC1(gene name synonym)|uniprotkb:Mitochondrial ATP-Mg/Pi carrier protein 1(gene name synonym)|uniprotkb:"Mitochondrial Ca(2+)-dependent solute carrier protein 1"(gene name synonym)|uniprotkb:Small calcium-binding mitochondrial carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 24(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_037518.3|refseq:NP_998816.1|ensembl:ENSG00000085491(gene)|ensembl:ENSG00000284468(gene)|ensembl:ENST00000565488(transcript)|ensembl:ENST00000640416(transcript)|go:"GO:0005347"(ATP transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0010941"(regulation of cell death)|go:"GO:0015867"(ATP transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002167(Graves disease carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR018247|interpro:IPR023395|mint:Q6NUK1|rcsb pdb:4N5X|rcsb pdb:4ZCU|rcsb pdb:4ZCV	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:2zVynZiDVY5UzziL6TAmqK/fkB09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O00303	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9NUU6	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916492|ensembl:ENSP00000274217|uniprotkb:Q53H50|uniprotkb:Q9H037	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:otull_human(display_long)|uniprotkb:OTULINL(gene name)|psi-mi:OTULINL(display_short)|uniprotkb:FAM105A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000145569(gene)|ensembl:ENST00000274217(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0006508"(proteolysis)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|interpro:IPR023235|interpro:IPR023236|rcsb pdb:6DRM|refseq:NP_061891.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:1T3mFQObV1rSXW0PAY8KQu87ucQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9BPX3	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-970214|uniprotkb:Q9HBI9|ensembl:ENSP00000251496|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000109805(gene)|ensembl:ENST00000251496(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_071741.2|dip:DIP-34891N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:G45XQBcnTeSunRz57s6lJErxvjo9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P17980	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-359720|uniprotkb:Q3B757|ensembl:ENSP00000298852|ensembl:ENSP00000481029|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002795.2|ensembl:ENSG00000165916(gene)|ensembl:ENST00000298852(transcript)|ensembl:ENST00000619920(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043921"(modulation by host of viral transcription)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|go:"GO:0036402"(proteasome-activating activity)|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-1236978|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27555N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q8NBJ5	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1057068|uniprotkb:Q8NC64|ensembl:ENSP00000252599	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:gt251_human(display_long)|uniprotkb:COLGALT1(gene name)|psi-mi:COLGALT1(display_short)|uniprotkb:"Collagen beta(1-O)galactosyltransferase 1"(gene name synonym)|uniprotkb:GLT25D1(gene name synonym)|uniprotkb:Glycosyltransferase 25 family member 1(gene name synonym)|uniprotkb:Hydroxylysine galactosyltransferase 1(gene name synonym)|uniprotkb:PSEC0241(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_078932.2|ensembl:ENSG00000130309(gene)|ensembl:ENST00000252599(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0050211"(procollagen galactosyltransferase activity)|go:"GO:1904028"(positive regulation of collagen fibril organization)|interpro:IPR002654(Glycosyl transferase, family 25)|interpro:IPR029044|mint:Q8NBJ5|reactome:R-HSA-1650814	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:nB7wFmsUKfA2+PrPaqw08fQpJRs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O75534	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-719186|uniprotkb:O94961|uniprotkb:Q5TF04|uniprotkb:Q5TF05|uniprotkb:Q68DI9|uniprotkb:Q9Y2S4|uniprotkb:E9PGZ0|uniprotkb:Q68DF1|intact:EBI-1059183|ensembl:ENSP00000351329|ensembl:ENSP00000432958|uniprotkb:A8K281|uniprotkb:G5E9Q2	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:csde1_human(display_long)|uniprotkb:Protein UNR(gene name synonym)|uniprotkb:N-ras upstream gene protein(gene name synonym)|uniprotkb:CSDE1(gene name)|psi-mi:CSDE1(display_short)|uniprotkb:D1S155E(gene name synonym)|uniprotkb:KIAA0885(gene name synonym)|uniprotkb:NRU(gene name synonym)|uniprotkb:UNR(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001007554.1|refseq:NP_001123995.1|refseq:NP_001229820.1|refseq:NP_001229821.1|refseq:NP_001229822.1|refseq:NP_009089.4|ensembl:ENSG00000009307(gene)|ensembl:ENST00000358528(transcript)|ensembl:ENST00000534699(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008584"(male gonad development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR019844|interpro:IPR024642|mint:O75534|rcsb pdb:1WFQ|rcsb pdb:1X65|rcsb pdb:2YTV|rcsb pdb:2YTX|rcsb pdb:2YTY|interpro:IPR012340(Nucleic acid-binding, OB-fold)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:fpL1bONjNXyXjIO/akUIIoeEGTc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P48643	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P08195	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P43246	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P49588	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-709710|uniprotkb:A6NF14|uniprotkb:Q53GV7|uniprotkb:Q96FA0|uniprotkb:B4DR45|ensembl:ENSP00000261772|ensembl:ENSP00000501924|ensembl:ENSP00000502247|ensembl:ENSP00000502797	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:syac_human(display_long)|uniprotkb:AARS1(gene name)|psi-mi:AARS1(display_short)|uniprotkb:AARS(gene name synonym)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-42(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001596.2|ensembl:ENSG00000090861(gene)|ensembl:ENST00000261772(transcript)|ensembl:ENST00000674691(transcript)|ensembl:ENST00000674963(transcript)|ensembl:ENST00000675643(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0002196"("Ser-tRNA(Ala) hydrolase activity")|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016597"(amino acid binding)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140018"(regulation of cytoplasmic translational fidelity)|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018162|interpro:IPR018163|interpro:IPR018164|interpro:IPR018165|interpro:IPR023033|mint:P49588|rcsb pdb:4XEM|rcsb pdb:4XEO|rcsb pdb:5KNN|rcsb pdb:5T5S|rcsb pdb:5T76|rcsb pdb:5V59|reactome:R-HSA-379716	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:e9+gLroLXvK8li0wiPBGbZhQqP49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P38646	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O75844	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1056377|uniprotkb:Q8NDZ8|uniprotkb:Q9UBQ2|uniprotkb:B3KQI7|uniprotkb:D3DPU7|ensembl:ENSP00000361845	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:face1_human(display_long)|uniprotkb:ZMPSTE24(gene name)|psi-mi:ZMPSTE24(display_short)|uniprotkb:FACE1(gene name synonym)|uniprotkb:STE24(gene name synonym)|uniprotkb:Prenyl protein-specific endoprotease 1(gene name synonym)|uniprotkb:Farnesylated proteins-converting enzyme 1(gene name synonym)|uniprotkb:Zinc metalloproteinase Ste24 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005848.2|ensembl:ENSG00000084073(gene)|ensembl:ENST00000372759(transcript)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030282"(bone mineralization)|go:"GO:0030327"(prenylated protein catabolic process)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043979"(histone H2B-K5 acetylation)|go:"GO:0044029"(hypomethylation of CpG island)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048538"(thymus development)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0050905"(neuromuscular process)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061762"(CAMKK-AMPK signaling cascade)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070302"(regulation of stress-activated protein kinase signaling cascade)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071586"(CAAX-box protein processing)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:1903025"(regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1903463"(regulation of mitotic cell cycle DNA replication)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990164"(histone H2A phosphorylation)|go:"GO:2000618"(regulation of histone H4-K16 acetylation)|go:"GO:2000730"(regulation of termination of RNA polymerase I transcription)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR001915(Peptidase M48, Ste24p)|interpro:IPR027057|interpro:IPR032456|rcsb pdb:2YPT|rcsb pdb:4AW6|rcsb pdb:5SYT|rcsb pdb:6BH8|dip:DIP-39641N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:OPwBYiVhnltoUrmk2Jtj07QDSCg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14787	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-431907|uniprotkb:O14655|intact:EBI-1053477|uniprotkb:Q6IN77|ensembl:ENSP00000407182|ensembl:ENSP00000468434	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tnpo2_human(display_long)|uniprotkb:Karyopherin beta-2b(gene name synonym)|uniprotkb:TNPO2(gene name)|psi-mi:TNPO2(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001129668.1|refseq:NP_001129667.1|refseq:NP_038461.2|ensembl:ENSG00000105576(gene)|ensembl:ENST00000425528(transcript)|ensembl:ENST00000592287(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:B+ZqD5TWiP/J6/ZwiM+39lO9E749606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P31040	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P55060	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O60506	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P55160	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916418|ensembl:ENSP00000293373|uniprotkb:B4DUT5|uniprotkb:Q52LW0	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:nckpl_human(display_long)|uniprotkb:NCKAP1L(gene name)|psi-mi:NCKAP1L(display_short)|uniprotkb:HEM1(gene name synonym)|uniprotkb:Hematopoietic protein 1(gene name synonym)|uniprotkb:Membrane-associated protein HEM-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000123338(gene)|ensembl:ENST00000293373(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031209"(SCAR complex)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043318"(negative regulation of cytotoxic T cell degranulation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1904515"(positive regulation of TORC2 signaling)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR019137|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171905.1|refseq:NP_005328.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:vP30ryoYJl7bNK49EYpsoWplZ4Q9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P53621	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P38405	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2512639|ensembl:ENSP00000269162|ensembl:ENSP00000408489|ensembl:ENSP00000439023|uniprotkb:Q86XU3|uniprotkb:B7ZA26	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:gnal_human(display_long)|uniprotkb:GNAL(gene name)|psi-mi:GNAL(display_short)|uniprotkb:Adenylate cyclase-stimulating G alpha protein, olfactory type(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000141404(gene)|ensembl:ENST00000269162(transcript)|ensembl:ENST00000423027(transcript)|ensembl:ENST00000535121(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007606"(sensory perception of chemical stimulus)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-HSA-170660|reactome:R-HSA-170670|reactome:R-HSA-381753|refseq:NP_001135811.1|refseq:NP_892023.1|refseq:NP_001248372.1|refseq:NP_001248373.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:IC+CI3TYQdbioxaPBNu/cSGn7TQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O15397	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-358808|intact:EBI-28976929|ensembl:ENSP00000256079|uniprotkb:B7Z7M3	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006381.2|ensembl:ENSP00000256079|ensembl:ENST00000544829|ensembl:ENSP00000444520|ensembl:ENSG00000133704(gene)|ensembl:ENST00000256079(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|dip:DIP-44186N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P42167	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-455283|uniprotkb:Q14861|ensembl:ENSP00000450627|uniprotkb:A2T926	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:lap2b_human(display_long)|uniprotkb:Thymopoietin-related peptide isoforms beta/gamma(gene name synonym)|uniprotkb:Thymopoietin, isoforms beta/gamma(gene name synonym)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001294904.1|refseq:NP_001027454.1|refseq:NP_001027455.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000556029(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:P42167|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|dip:DIP-43686N|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:S2mYrSugx0Ms4vhw/vYYH/SthOw9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O00487	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-722193|uniprotkb:O00176|uniprotkb:B3KNW2|ensembl:ENSP00000386541	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:psde_human(display_long)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)|uniprotkb:26S proteasome-associated PAD1 homolog 1(gene name synonym)|uniprotkb:PSMD14(gene name)|psi-mi:PSMD14(display_short)|uniprotkb:POH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005796.1|ensembl:ENSG00000115233(gene)|ensembl:ENST00000409682(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|mint:O00487|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:pSM+755ZbQisR5S0ZivcYBu9Bc49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9UBB4	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-702390|uniprotkb:O14998|uniprotkb:O15009|uniprotkb:Q6I9X4|uniprotkb:A6NLC4|uniprotkb:B4DG05|ensembl:ENSP00000252934	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:atx10_human(display_long)|uniprotkb:Spinocerebellar ataxia type 10 protein(gene name synonym)|uniprotkb:Brain protein E46 homolog(gene name synonym)|uniprotkb:ATXN10(gene name)|psi-mi:ATXN10(display_short)|uniprotkb:SCA10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001161093.1|refseq:NP_037368.1|ensembl:ENSG00000130638(gene)|ensembl:ENST00000252934(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060271"(cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019156|mint:Q9UBB4	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:kQ+1aM5ZEzIlpH2lKWFGVSrCDww9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q16543	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:iajhitd2iEmd17KfpU/nMaKc4049606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q12824	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P54136	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355482|uniprotkb:Q9BWA1|uniprotkb:B2RBS9|uniprotkb:Q53GY4|intact:EBI-28985219|ensembl:ENSP00000231572	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:syrc_human(display_long)|uniprotkb:RARS1(gene name)|psi-mi:RARS1(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:RARS(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002878.2|ensembl:ENSG00000113643(gene)|ensembl:ENST00000231572(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0034618"(arginine binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:P54136|rcsb pdb:4Q2T|rcsb pdb:4Q2X|rcsb pdb:4Q2Y|rcsb pdb:4R3Z|rcsb pdb:4ZAJ|reactome:R-HSA-2408522|reactome:R-HSA-379716|ensembl:ENSP00000231572	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:oM9gWF1NucjgVjBFm4DcjmnQNCE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q13263	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P63261	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P28340	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-716569|uniprotkb:Q8NER3|uniprotkb:Q96H98|ensembl:ENSP00000406046|ensembl:ENSP00000472600|ensembl:ENSP00000473052	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dpod1_human(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNA polymerase subunit delta p125(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short)|uniprotkb:POLD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002682.2|refseq:XP_011525340.1|refseq:NP_001243778.1|ensembl:ENSG00000062822(gene)|ensembl:ENST00000599857(transcript)|ensembl:ENST00000601098(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0009411"(response to UV)|ensembl:ENST00000440232(transcript)|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-5358606|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019899"(enzyme binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017964|interpro:IPR023211|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|mint:P28340|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-2564830|reactome:R-HSA-5358565|refseq:XP_016882370.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:bJ5Q0xOzHga/zxMOBHkuXaFXeLw9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9UIA9	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-286668|uniprotkb:O94846|uniprotkb:Q6PJK9|uniprotkb:Q8NEK7|ensembl:ENSP00000252512	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:xpo7_human(display_long)|uniprotkb:Ran-binding protein 16(gene name synonym)|uniprotkb:XPO7(gene name)|psi-mi:XPO7(display_short)|uniprotkb:KIAA0745(gene name synonym)|uniprotkb:RANBP16(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_055839.3|ensembl:ENSG00000130227(gene)|ensembl:ENST00000252512(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|mint:Q9UIA9	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:v+DQUTgId55XuRlCPZ4tq7fIing9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15392	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-5457558|uniprotkb:B7Z817|ensembl:ENSP00000360316|ensembl:ENSP00000416585|uniprotkb:D3DQ51|uniprotkb:Q9HBA8|intact:EBI-10964490	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dhc24_human(display_long)|uniprotkb:DHCR24(gene name)|psi-mi:DHCR24(display_short)|uniprotkb:KIAA0018(gene name synonym)|uniprotkb:24-dehydrocholesterol reductase(gene name synonym)|uniprotkb:Diminuto/dwarf1 homolog(gene name synonym)|uniprotkb:Seladin-1(gene name synonym)|uniprotkb:3-beta-hydroxysterol Delta-24-reductase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000116133(gene)|ensembl:ENST00000371269(transcript)|ensembl:ENST00000436604(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000246"("delta24(24-1) sterol reductase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0009888"(tissue development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016628"(oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0030539"(male genitalia development)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0050614"(delta24-sterol reductase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061024"(membrane organization)|go:"GO:0071949"(FAD binding)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318|interpro:IPR040165|go:"GO:0005737"(cytoplasm)|mint:Q15392|reactome:R-HSA-6807047|reactome:R-HSA-6807062|refseq:NP_055577.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:kg8bxZHxFFTUmvP9UQMeVFRNWQM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q3SY69	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916128|ensembl:ENSP00000258494|uniprotkb:Q3SY68|uniprotkb:Q68D62|uniprotkb:Q6AI55|uniprotkb:Q8N922	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:al1l2_human(display_long)|uniprotkb:ALDH1L2(gene name)|psi-mi:ALDH1L2(display_short)|uniprotkb:Aldehyde dehydrogenase family 1 member L2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011536291.1|ensembl:ENST00000258494(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009258"(10-formyltetrahydrofolate catabolic process)|go:"GO:0016155"(formyltetrahydrofolate dehydrogenase activity)|go:"GO:0016742"(hydroxymethyl-, formyl- and related transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR011407(10-formyltetrahydrofolate dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|ensembl:ENSG00000136010(gene)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|interpro:IPR036477|interpro:IPR036736|interpro:IPR037022|mint:Q3SY69|reactome:R-HSA-196757|refseq:NP_001029345.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Tfg9TJwXfyRvVxezABcOGaJrcas9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15386	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1058871|uniprotkb:A4D235|uniprotkb:A6NCP3|uniprotkb:Q8TC15|uniprotkb:Q96CR4|uniprotkb:Q9UDU3|intact:EBI-1237492|ensembl:ENSP00000309198	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ube3c_human(display_long)|uniprotkb:UBE3C(gene name)|psi-mi:UBE3C(display_short)|uniprotkb:KIAA0010(gene name synonym)|uniprotkb:KIAA10(gene name synonym)|uniprotkb:HectH2(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_055486.2|ensembl:ENSG00000009335(gene)|ensembl:ENST00000348165(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000569(HECT)|interpro:IPR035983|interpro:IPR044611|rcsb pdb:6K2C|reactome:R-HSA-983168|go:"GO:0000502"(proteasome complex)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:dgGb2MVtbVnFuuUAnlX4YIT39lE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P40939	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15020	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-308619|uniprotkb:Q2M2H0|uniprotkb:Q58F06|uniprotkb:Q8IUS1|uniprotkb:Q96J95|uniprotkb:A8K2E4|uniprotkb:B7ZKM0|ensembl:ENSP00000449386|intact:EBI-11138149	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sart3_human(display_long)|uniprotkb:KIAA0156(gene name synonym)|uniprotkb:SART3(gene name)|psi-mi:SART3(display_short)|uniprotkb:TIP110(gene name synonym)|uniprotkb:Tat-interacting protein of 110 kDa(gene name synonym)|uniprotkb:p110 nuclear RNA-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000075856(gene)|ensembl:ENST00000546815(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030624"(U6atac snRNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0061574"(ASAP complex)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903586"(positive regulation of histone deubiquitination)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008669(Lsm interaction)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034217|interpro:IPR034218|interpro:IPR035979|mint:Q15020|rcsb pdb:2DO4|rcsb pdb:5CTQ|rcsb pdb:5CTR|rcsb pdb:5CTT|rcsb pdb:5JJW|rcsb pdb:5JJX|rcsb pdb:5JPZ|refseq:NP_055521.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:/71mWOMJti/LCvNo2WjCAmIYUCk9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P13010	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9H257	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-751319|uniprotkb:Q5SXM6|uniprotkb:Q9H854|uniprotkb:Q5SXM5|ensembl:ENSP00000360797	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:card9_human(display_long)|uniprotkb:CARD9(gene name)|psi-mi:CARD9(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_434700.2|refseq:NP_434701.1|ensembl:ENSG00000187796(gene)|ensembl:ENST00000371732(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0032449"(CBM complex)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0048874"(host-mediated regulation of intestinal microbiota composition)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:2000318"(positive regulation of T-helper 17 type immune response)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR042142|rcsb pdb:6E25|rcsb pdb:6E26|rcsb pdb:6E27|rcsb pdb:6E28|rcsb pdb:6N2M|rcsb pdb:6N2P|reactome:R-HSA-168638|reactome:R-HSA-5607764|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032663"(regulation of interleukin-2 production)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043621"(protein self-association)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:GdIGj/zy8i6nOYzprgAjkAVOLKY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q70UQ0	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2557212|uniprotkb:Q96ND2|uniprotkb:Q86V91|uniprotkb:Q6ZWH4|uniprotkb:Q70UP9|ensembl:ENSP00000343471	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ikip_human(display_long)|uniprotkb:IKIP(gene name synonym)|uniprotkb:IKBIP(gene name)|psi-mi:IKBIP(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000166130(gene)|ensembl:ENST00000342502(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010165"(response to X-ray)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR024152|mint:Q70UQ0|refseq:NP_710154.1|refseq:NP_963906.1|refseq:NP_963907.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:wUhuKhwmOyjUTYSF8or1Tc0Iu189606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P23526	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1053240|uniprotkb:Q96A36|ensembl:ENSP00000217426|uniprotkb:B3KUN3|uniprotkb:F5H737|uniprotkb:A8K307|uniprotkb:E1P5P2	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sahh_human(display_long)|uniprotkb:S-adenosyl-L-homocysteine hydrolase(gene name synonym)|uniprotkb:AHCY(gene name)|psi-mi:AHCY(display_short)|uniprotkb:SAHH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000678.1|refseq:NP_001155238.1|ensembl:ENSG00000101444(gene)|ensembl:ENST00000217426(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002439"(chronic inflammatory response to antigenic stimulus)|go:"GO:0004013"(adenosylhomocysteinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0019510"(S-adenosylhomocysteine catabolic process)|go:"GO:0030554"(adenyl nucleotide binding)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0042470"(melanosome)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:P23526|rcsb pdb:1A7A|rcsb pdb:1LI4|refseq:XP_011526961.1|refseq:XP_005260374.1|refseq:NP_001309013.1|refseq:NP_001309014.1|rcsb pdb:3NJ4|rcsb pdb:4PFJ|rcsb pdb:4PGF|rcsb pdb:4YVF|rcsb pdb:5W49|rcsb pdb:5W4B|reactome:R-HSA-156581|reactome:R-HSA-1614635|reactome:R-HSA-2408508|reactome:R-HSA-5578997|refseq:XP_016883197.1|refseq:XP_016883198.1|dip:DIP-50557N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:+y7rwgw9EIMaVrkt4/9kbZM44sg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q01813	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-359022|uniprotkb:B3KS15|uniprotkb:Q5VSR7|uniprotkb:Q5VSR8|ensembl:ENSP00000370517	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pfkap_human(display_long)|uniprotkb:PFKP(gene name)|psi-mi:PFKP(display_short)|uniprotkb:PFKF(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme C(gene name synonym)|uniprotkb:6-phosphofructokinase type C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002618.1|ensembl:ENSG00000067057(gene)|ensembl:ENST00000381125(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:Q01813|rcsb pdb:4RH3|rcsb pdb:4U1R|rcsb pdb:4WL0|rcsb pdb:4XYJ|rcsb pdb:4XYK|rcsb pdb:4XZ2|reactome:R-HSA-70171|refseq:NP_001229268.1|dip:DIP-45850N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:GNmWbFrQsTMRdVphWG+3DK3wxaA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P20648	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916197|ensembl:ENSP00000262623|uniprotkb:O00738	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:atp4a_human(display_long)|uniprotkb:ATP4A(gene name)|psi-mi:ATP4A(display_short)|uniprotkb:"Gastric H(+)/K(+) ATPase subunit alpha"(gene name synonym)|uniprotkb:Proton pump(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000105675(gene)|ensembl:ENST00000262623(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008900"("P-type potassium:proton transporter activity")|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030955"(potassium ion binding)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR015127(Gastric H+/K+-ATPase, N terminal)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P20648|reactome:R-HSA-936837|refseq:NP_000695.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:nMruHDqjaCmOuGtZh3ViVzlMqYo9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q06210	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1055540|uniprotkb:Q9BXF8|uniprotkb:Q53QE6|ensembl:ENSP00000349860	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:gfpt1_human(display_long)|uniprotkb:D-fructose-6-phosphate amidotransferase 1(gene name synonym)|uniprotkb:Hexosephosphate aminotransferase 1(gene name synonym)|uniprotkb:GFPT1(gene name)|psi-mi:GFPT1(display_short)|uniprotkb:GFAT(gene name synonym)|uniprotkb:GFPT(gene name synonym)|uniprotkb:"Glutamine:fructose-6-phosphate amidotransferase 1"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002047.2|refseq:NP_001231639.1|ensembl:ENSG00000198380(gene)|ensembl:ENST00000357308(transcript)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR017932|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490|mint:Q06210|rcsb pdb:2V4M|rcsb pdb:2ZJ3|rcsb pdb:2ZJ4|rcsb pdb:6R4E|rcsb pdb:6R4F|rcsb pdb:6R4G|rcsb pdb:6R4H|rcsb pdb:6R4I|rcsb pdb:6R4J|rcsb pdb:6SVM|rcsb pdb:6SVO|rcsb pdb:6SVP|rcsb pdb:6SVQ|rcsb pdb:6ZMJ|rcsb pdb:6ZMK|rcsb pdb:7NDL|reactome:R-HSA-381038|reactome:R-HSA-4085023|reactome:R-HSA-446210	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:fP9V7Qv/Wv8EaxMa0lrY4icjCno9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P14625	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q16555	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P26639	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1042683|uniprotkb:Q96FP5|uniprotkb:Q9BWA6|uniprotkb:A8K8I1|ensembl:ENSP00000265112|ensembl:ENSP00000424387|uniprotkb:B4DEG8	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sytc_human(display_long)|uniprotkb:TARS1(gene name)|psi-mi:TARS1(display_short)|uniprotkb:TARS(gene name synonym)|uniprotkb:Threonyl-tRNA synthetase(gene name synonym)|uniprotkb:Threonyl-tRNA synthetase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_689508.3|refseq:NP_001245367.1|rcsb pdb:4HWT|rcsb pdb:4P3N|rcsb pdb:4TTV|rcsb pdb:5XLN|reactome:R-HSA-379716|refseq:NP_001245366.1|go:"GO:0005829"(cytosol)|go:"GO:0006435"(threonyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002320(Threonyl-tRNA synthetase, class IIa)|interpro:IPR004095(TGS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensembl:ENSG00000113407(gene)|interpro:IPR012676(TGS-like)|ensembl:ENST00000265112(transcript)|ensembl:ENST00000502553(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004829"(threonine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018163|interpro:IPR033728|interpro:IPR036621|mint:P26639|rcsb pdb:1WWT	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Z+rOaI1ZO1TQftfkRn1HhXUqDAk9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9C0E2	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1044855|uniprotkb:Q5VUZ5|uniprotkb:Q9H934|uniprotkb:Q8N3V6|ensembl:ENSP00000255305	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:xpo4_human(display_long)|uniprotkb:XPO4(gene name)|psi-mi:XPO4(display_short)|uniprotkb:KIAA1721(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_071904.4|ensembl:ENSG00000132953(gene)|ensembl:ENST00000255305(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|mint:Q9C0E2|go:"GO:0005643"(nuclear pore)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:+7lQFg9CBnDLFt9rqjLb//HPJnQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P08240	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-726981|ensembl:ENSP00000328023|uniprotkb:Q9BVJ4|uniprotkb:A6NIB3|uniprotkb:B2R5Z8|uniprotkb:B4E0H3|uniprotkb:E9PJS4	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:srpra_human(display_long)|uniprotkb:SRPRA(gene name)|psi-mi:SRPRA(display_short)|uniprotkb:Docking protein alpha(gene name synonym)|uniprotkb:SRPR(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:2FH5|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|rcsb pdb:2GO5|go:"GO:0045047"(protein targeting to ER)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|rcsb pdb:5L3Q|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007222(Signal recognition particle receptor, alpha subunit, N-terminal)|interpro:IPR011012(Longin-like)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101|mint:P08240|rcsb pdb:6Y32|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|ensembl:ENSG00000182934(gene)|ensembl:ENST00000332118(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005785"(signal recognition particle receptor complex)|refseq:NP_001171313.1|refseq:NP_003130.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:4ag/lxPfDGSDWhpnuwQynTvCpuU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q3ZCQ8	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P55084	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P41226	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-751921|uniprotkb:Q9BRB2|ensembl:ENSP00000333266	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:uba7_human(display_long)|uniprotkb:UBE1L(gene name synonym)|uniprotkb:UBE2(gene name synonym)|uniprotkb:UBA7(gene name)|psi-mi:UBA7(display_short)|uniprotkb:Ubiquitin-activating enzyme E1 homolog(gene name synonym)|uniprotkb:D8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003326.2|dip:DIP-60526N|ensembl:ENSG00000182179(gene)|ensembl:ENST00000333486(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019782"(ISG15 activating enzyme activity)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0032446"(protein modification by small protein conjugation)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-936440|reactome:R-HSA-983168|go:"GO:0005524"(ATP binding)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:SQ25p6ScP5T89S0GtIhukmWjQGQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9UBM7	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1054468|uniprotkb:O60492|uniprotkb:O60717|uniprotkb:B2R6Z2|ensembl:ENSP00000347717|ensembl:ENSP00000384739	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dhcr7_human(display_long)|uniprotkb:"Sterol Delta(7)-reductase"(gene name synonym)|uniprotkb:DHCR7(gene name)|psi-mi:DHCR7(display_short)|uniprotkb:D7SR(gene name synonym)|uniprotkb:Delta7-sterol reductase(gene name synonym)|uniprotkb:Sterol reductase SR-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001157289.1|refseq:NP_001351.2|mint:Q9UBM7|reactome:R-HSA-2426168|reactome:R-HSA-6807047|reactome:R-HSA-6807062|interpro:IPR018083|ensembl:ENSG00000172893(gene)|ensembl:ENST00000355527(transcript)|ensembl:ENST00000407721(transcript)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0009918"(sterol delta7 reductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016132"(brassinosteroid biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0047598"(7-dehydrocholesterol reductase activity)|go:"GO:0050661"(NADP binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:op53bBpGaOM0Ysy4Bn5q6qXcKgI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9NUQ9	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1055930|uniprotkb:Q96AZ5|uniprotkb:Q9NZE7|uniprotkb:Q9NW21|ensembl:ENSP00000384880|ensembl:ENSP00000428117|ensembl:ENSP00000429078|ensembl:ENSP00000429150|ensembl:ENSP00000429499|ensembl:ENSP00000429802|ensembl:ENSP00000430674	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cyrib_human(display_long)|uniprotkb:CYRIB(gene name)|psi-mi:CYRIB(display_short)|uniprotkb:CYRI(gene name synonym)|uniprotkb:FAM49B(gene name synonym)|uniprotkb:L1(gene name synonym)|uniprotkb:BM-009(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011515410.1|refseq:XP_011515411.1|refseq:XP_011515412.1|refseq:XP_011515413.1|refseq:XP_011515415.1|refseq:XP_011515414.1|refseq:NP_001243692.1|refseq:XP_011515416.1|refseq:XP_011515417.1|refseq:XP_011515423.1|refseq:XP_011515424.1|refseq:XP_011515425.1|refseq:XP_011515426.1|refseq:XP_011515427.1|refseq:NP_057707.3|ensembl:ENSG00000153310(gene)|ensembl:ENST00000401979(transcript)|ensembl:ENST00000517654(transcript)|ensembl:ENST00000519110(transcript)|ensembl:ENST00000519540(transcript)|ensembl:ENST00000519824(transcript)|ensembl:ENST00000522746(transcript)|ensembl:ENST00000523509(transcript)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0023030"(MHC class Ib protein binding, via antigen binding groove)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000568"(positive regulation of memory T cell activation)|interpro:IPR009828(Protein of unknown function DUF1394)|interpro:IPR039789|rcsb pdb:7AJK|reactome:R-HSA-114608|refseq:NP_001317541.1|refseq:XP_016869028.1|refseq:XP_016869029.1|refseq:XP_016869030.1|refseq:XP_016869031.1|refseq:XP_016869032.1|refseq:XP_016869033.1|refseq:XP_016869034.1|refseq:XP_016869035.1|refseq:XP_016869036.1|refseq:XP_016869037.1|refseq:XP_016869038.1|refseq:XP_016869039.1|refseq:XP_016869040.1|refseq:XP_016869047.1|refseq:XP_016869048.1|refseq:XP_016869049.1|refseq:XP_016869050.1|refseq:XP_016869051.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:x123Rh78yRGOGEgYIBIm/a+45ss9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q12904	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1045802|uniprotkb:Q6FG28|uniprotkb:Q96CQ9|uniprotkb:B4E1S7|uniprotkb:B3KTR2|ensembl:ENSP00000350699|ensembl:ENSP00000499850|ensembl:ENSP00000499921|ensembl:ENSP00000500025|ensembl:ENSP00000500159|ensembl:ENSP00000500170|ensembl:ENSP00000500620|ensembl:ENSP00000500668|ensembl:ENSP00000500732|ensembl:ENSP00000500794	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:aimp1_human(display_long)|uniprotkb:AIMP1(gene name)|psi-mi:AIMP1(display_short)|uniprotkb:EMAP2(gene name synonym)|uniprotkb:SCYE1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001135887.1|refseq:NP_001135888.1|refseq:NP_004748.2|ensembl:ENSG00000164022(gene)|ensembl:ENST00000358008(transcript)|ensembl:ENST00000671868(transcript)|ensembl:ENST00000671960(transcript)|ensembl:ENST00000672285(transcript)|ensembl:ENST00000672328(transcript)|ensembl:ENST00000672337(transcript)|ensembl:ENST00000672341(transcript)|ensembl:ENST00000672911(transcript)|ensembl:ENST00000673018(transcript)|ensembl:ENST00000673123(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051020"(GTPase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070094"(positive regulation of glucagon secretion)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q12904|rcsb pdb:1E7Z|rcsb pdb:1EUJ|rcsb pdb:1FL0|rcsb pdb:4R3Z|reactome:R-HSA-2408522|reactome:R-HSA-379716|refseq:XP_016864324.1|refseq:XP_016864325.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:UtCeSRjFyuuEHUxVF2HkG9RA55k9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O43432	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-464766|uniprotkb:Q5SWC3|ensembl:ENSP00000264211|uniprotkb:Q15597|uniprotkb:Q8NEN1|uniprotkb:Q504Z1|uniprotkb:B9EGQ7	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:if4g3_human(display_long)|uniprotkb:EIF4G3(gene name)|psi-mi:EIF4G3(display_short)|uniprotkb:eIF-4-gamma II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENST00000264211(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037585|mint:O43432|rcsb pdb:1HU3|reactome:R-HSA-1169408|ensembl:ENSG00000075151(gene)|refseq:NP_001185732.1|refseq:NP_003751.2|ensembl:ENSP00000264211|ensembl:ENST00000356916|ensembl:ENSP00000349386|ensembl:ENST00000374935|ensembl:ENSP00000364071|ensembl:ENST00000602326|ensembl:ENSP00000473510|ensembl:ENST00000682284|ensembl:ENSP00000507819|refseq:NP_001185731.1|refseq:NP_001185730.1|refseq:XP_016858189.1|refseq:XP_016858197.1|refseq:XP_016858201.1|dip:DIP-33245N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:dN5046U5kz1WfBJD0+NWYMMU6RY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P12956	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P04040	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2432181|uniprotkb:A8K6C0|uniprotkb:B2RCZ9|uniprotkb:Q9UC85|uniprotkb:Q2M1U4|uniprotkb:Q4VXX5|uniprotkb:Q9BWT9|uniprotkb:D3DR07|ensembl:ENSP00000241052	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cata_human(display_long)|uniprotkb:CAT(gene name)|psi-mi:CAT(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001743.1|ensembl:ENSG00000121691(gene)|ensembl:ENST00000241052(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0004096"(catalase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009642"(response to light intensity)|go:"GO:0009650"(UV protection)|go:"GO:0010193"(response to ozone)|go:"GO:0010288"(response to lead ion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0016020"(membrane)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0080184"(response to phenylpropanoid)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P04040|rcsb pdb:1DGB|rcsb pdb:1DGF|rcsb pdb:1DGG|rcsb pdb:1DGH|rcsb pdb:1F4J|rcsb pdb:1QQW|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9615017	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:IWdPQIuCq9vCj8I0HmshkJwAAqg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P05388	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P06576	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P17858	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-487243|uniprotkb:Q96A64|uniprotkb:Q96IH4|uniprotkb:Q9BR91|ensembl:ENSP00000269848	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pfkal_human(display_long)|uniprotkb:PFKL(gene name)|psi-mi:PFKL(display_short)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme B(gene name synonym)|uniprotkb:6-phosphofructokinase type B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001002021.2|refseq:NP_002617.3|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P17858|reactome:R-HSA-6798695|reactome:R-HSA-70171|ensembl:ENSG00000141959(gene)|ensembl:ENST00000349048(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:lP9/V5WcCl5rLpy4QEZnWkLCCcQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P05023	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q96JJ3	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-3959230|ensembl:ENSP00000290246|ensembl:ENSP00000379673|uniprotkb:Q9NQQ6|uniprotkb:Q5JVZ6|uniprotkb:E1P5T3|uniprotkb:Q9HAH0|uniprotkb:Q9H9L5|uniprotkb:Q9H938|uniprotkb:Q96PA9|uniprotkb:Q96CJ2|uniprotkb:Q96ME5|uniprotkb:Q7Z5G9	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:elmo2_human(display_long)|uniprotkb:ELMO2(gene name)|psi-mi:ELMO2(display_short)|uniprotkb:CED12A(gene name synonym)|uniprotkb:KIAA1834(gene name synonym)|uniprotkb:Protein ced-12 homolog A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000062598(gene)|ensembl:ENST00000290246(transcript)|ensembl:ENST00000396391(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0048870"(cell motility)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006816(Engulfment and cell motility, ELM)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024574|interpro:IPR030713|rcsb pdb:6IDX|rcsb pdb:6IE1|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9013408|reactome:R-HSA-9664422|refseq:NP_001305182.1|refseq:NP_573403.1|refseq:NP_877496.1|refseq:XP_005260553.1|refseq:XP_006723917.1|refseq:XP_005260555.1|refseq:XP_005260556.1|refseq:XP_005260557.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:dXWjmEDxNMqr2k3/jdmSPB35MM49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P36957	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-351007|uniprotkb:Q9BQ32|uniprotkb:Q7LDY7|intact:EBI-2511564|uniprotkb:B7Z5W8|uniprotkb:E7ESY5|ensembl:ENSP00000335304	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:odo2_human(display_long)|uniprotkb:DLST(gene name)|psi-mi:DLST(display_short)|uniprotkb:DLTS(gene name synonym)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001924.2|ensembl:ENSG00000119689(gene)|ensembl:ENST00000334220(transcript)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0034451"(centriolar satellite)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0106077"(histone succinylation)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|mint:P36957|rcsb pdb:6H05|reactome:R-HSA-389661|reactome:R-HSA-71064|reactome:R-HSA-71403	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:lZLUcTHB/dxXBTI/IXnSjyuVmBo9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q04637	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15366	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q8NBX0	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-4289902|uniprotkb:Q9Y363|uniprotkb:Q8TAR0|ensembl:ENSP00000355467	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:scpdl_human(display_long)|uniprotkb:SCCPDH(gene name)|psi-mi:SCCPDH(display_short)|uniprotkb:CGI-49(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000143653(gene)|ensembl:ENST00000366510(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030496"(midbody)|go:"GO:0031093"(platelet alpha granule lumen)|interpro:IPR005097(Saccharopine dehydrogenase)|interpro:IPR032095|interpro:IPR036291|reactome:R-HSA-114608|refseq:NP_057086.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:3dd8OvU7odCDI/f4Ouk7CJYoxnI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q8WVX9	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1045879|uniprotkb:Q5CZA3|uniprotkb:D3DQW8|ensembl:ENSP00000346874	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:facr1_human(display_long)|uniprotkb:Male sterility domain-containing protein 2(gene name synonym)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short)|uniprotkb:MLSTD2(gene name synonym)|uniprotkb:UNQ2423/PRO4981(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_115604.1|ensembl:ENSG00000197601(gene)|ensembl:ENST00000354817(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0010025"(wax biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0080019"("fatty-acyl-CoA reductase (alcohol-forming) activity")|go:"GO:0102965"(alcohol-forming fatty acyl-CoA reductase activity)|interpro:IPR013120(Male sterility, NAD-binding)|interpro:IPR026055|interpro:IPR033640|interpro:IPR036291|mint:Q8WVX9|reactome:R-HSA-9640463	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:YKZzt4lpIwBaWwckb0ZP9Wh8Q8k9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O43143	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q92973	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-286693|intact:EBI-1760498|uniprotkb:Q92957|uniprotkb:Q92975|intact:EBI-1965561|uniprotkb:B4DVC6|ensembl:ENSP00000336712	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tnpo1_human(display_long)|uniprotkb:TRN(gene name synonym)|uniprotkb:TNPO1(gene name)|psi-mi:TNPO1(display_short)|uniprotkb:KPNB2(gene name synonym)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Importin beta-2(gene name synonym)|uniprotkb:Karyopherin beta-2(gene name synonym)|uniprotkb:M9 region interaction protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002261.3|refseq:NP_694858.1|refseq:XP_005248557.1|dip:DIP-29335N|ensembl:ENSG00000083312(gene)|ensembl:ENST00000337273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q92973|rcsb pdb:1QBK|rcsb pdb:2H4M|rcsb pdb:2OT8|rcsb pdb:2QMR|rcsb pdb:2Z5J|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:2Z5N|rcsb pdb:2Z5O|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:4JLQ|rcsb pdb:4OO6|rcsb pdb:5J3V|rcsb pdb:5TQC|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:7CYL|reactome:R-HSA-450513|reactome:R-HSA-5620924|reactome:R-HSA-9615933	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:n8Q3n1rmTiJAp6f8DBcBV6j6lac9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P05091	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-711703|uniprotkb:Q03639|uniprotkb:Q6IB13|uniprotkb:Q6IV71|uniprotkb:B4DW54|uniprotkb:E7EUE5|ensembl:ENSP00000261733	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:aldh2_human(display_long)|uniprotkb:ALDH class 2(gene name synonym)|uniprotkb:ALDHI(gene name synonym)|uniprotkb:ALDH-E2(gene name synonym)|uniprotkb:ALDH2(gene name)|psi-mi:ALDH2(display_short)|uniprotkb:ALDM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000681.2|refseq:NP_001191818.1|dip:DIP-40262N|ensembl:ENSG00000111275(gene)|ensembl:ENST00000261733(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0004030"("aldehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P05091|rcsb pdb:1CW3|rcsb pdb:1NZW|rcsb pdb:1NZX|rcsb pdb:1NZZ|rcsb pdb:1O00|rcsb pdb:1O01|rcsb pdb:1O02|rcsb pdb:1O04|rcsb pdb:1O05|rcsb pdb:1ZUM|rcsb pdb:2ONM|rcsb pdb:2ONN|rcsb pdb:2ONO|rcsb pdb:2ONP|rcsb pdb:2VLE|rcsb pdb:3INJ|rcsb pdb:3INL|rcsb pdb:3N80|rcsb pdb:3N81|rcsb pdb:3N82|rcsb pdb:3N83|rcsb pdb:3SZ9|rcsb pdb:4FQF|rcsb pdb:4FR8|rcsb pdb:4KWF|rcsb pdb:4KWG|rcsb pdb:5L13|reactome:R-HSA-380612|reactome:R-HSA-71384	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:XvszkFUJP4cXHCYokY16c+LeDEI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P19338	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P53618	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14980	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P42166	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003267.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000266732(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045296"(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q14155	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-717515|uniprotkb:B1ALK6|uniprotkb:B1ALK8|uniprotkb:Q3LIA4|uniprotkb:Q5W9H0|uniprotkb:Q6P9G3|uniprotkb:Q6PII2|uniprotkb:Q86W63|uniprotkb:Q8N3M1|ensembl:ENSP00000364893	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:arhg7_human(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001307782.1|refseq:NP_663788.1|refseq:NP_001106983.1|refseq:NP_001106984.1|refseq:NP_001106985.1|refseq:NP_001307780.1|refseq:NP_001307783.1|refseq:NP_001317526.1|refseq:NP_001317527.1|ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0005925"(focal adhesion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:Q14155|rcsb pdb:1BY1|rcsb pdb:1ZSG|rcsb pdb:2L3G|rcsb pdb:5SXP|reactome:R-HSA-182971|reactome:R-HSA-193648|reactome:R-HSA-3928664|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9619229|dip:DIP-40794N|refseq:NP_003890.1|refseq:XP_016876313.1|refseq:XP_016876314.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P62714	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P09471	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-715087|uniprotkb:P29777|uniprotkb:Q8TD72|uniprotkb:Q9UMV4|intact:EBI-2558210|ensembl:ENSP00000262493|ensembl:ENSP00000491223	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:gnao_human(display_long)|uniprotkb:GNAO1(gene name)|psi-mi:GNAO1(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_066268.1|refseq:NP_620073.2|ensembl:ENSG00000087258(gene)|ensembl:ENST00000262493(transcript)|ensembl:ENST00000638705(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043209"(myelin sheath)|go:"GO:0043278"(response to morphine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044297"(cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0051926"(negative regulation of calcium ion transport)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P09471|rcsb pdb:6FUF|rcsb pdb:6G79|rcsb pdb:6K41|rcsb pdb:6OIK|rcsb pdb:6WWZ|rcsb pdb:7D76|rcsb pdb:7D77|reactome:R-HSA-4086398	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:z55dsHfgpwFC/q0mtQHF3HkBMJo9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q99460	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357874|uniprotkb:Q24JU0|uniprotkb:Q53TI2|uniprotkb:Q6GMU5|uniprotkb:Q6P2P4|uniprotkb:Q6PJM7|uniprotkb:Q6PKG9|uniprotkb:B8ZZH9|uniprotkb:Q86VU1|uniprotkb:Q8IV79|ensembl:ENSP00000309474|ensembl:ENSP00000503068	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:psmd1_human(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001177966.1|refseq:NP_002798.2|dip:DIP-27548N|ensembl:ENSG00000173692(gene)|ensembl:ENST00000308696(transcript)|ensembl:ENST00000677230(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|mint:Q99460|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6CO4|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6OI4|rcsb pdb:6UYI|rcsb pdb:6UYJ|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-382556|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:aGYxoT30PhzvF/CiurQLDb8Ewrs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q02218	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-747213|intact:EBI-1210683|uniprotkb:Q9UDX0|uniprotkb:D3DVL0|uniprotkb:B4E2U9|uniprotkb:E9PBM1|uniprotkb:Q96DD3|ensembl:ENSP00000222673	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:odo1_human(display_long)|uniprotkb:OGDH(gene name)|psi-mi:OGDH(display_short)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002532.2|refseq:NP_001003941.1|refseq:NP_001158508.1|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0021756"(striatum development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034602"("oxoglutarate dehydrogenase (NAD+) activity")|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0106077"(histone succinylation)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|rcsb pdb:3ERY|reactome:R-HSA-389661|reactome:R-HSA-71064|reactome:R-HSA-71403|ensembl:ENSG00000105953(gene)|ensembl:ENST00000222673(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0021695"(cerebellar cortex development)|dip:DIP-39353N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:B9CSRCmhDYg7n5jSpuDlr2mrxDg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P23634	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1174388|uniprotkb:Q13450|uniprotkb:Q13452|uniprotkb:Q13455|uniprotkb:Q16817|uniprotkb:Q7Z3S1|uniprotkb:B1APW6|uniprotkb:B1APW5	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:at2b4_human(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 4(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 4(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 1(gene name synonym)|uniprotkb:ATP2B4(gene name)|psi-mi:ATP2B4(display_short)|uniprotkb:ATP2B2(gene name synonym)|uniprotkb:MXRA1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001001396.1|refseq:NP_001675.3|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097228"(sperm principal piece)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|rcsb pdb:1CFF|rcsb pdb:2KNE|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|mint:P23634|dip:DIP-6128N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:XAjzRea7vq4vsbCVKdZRYIWvfBM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9NXR7	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-949389|ensembl:ENSP00000339371|ensembl:ENSP00000368945|uniprotkb:Q13880|uniprotkb:Q96P06|uniprotkb:A8K4X1|uniprotkb:Q4ZFX8|uniprotkb:Q53SD0|uniprotkb:Q969X9|uniprotkb:D6W562|uniprotkb:D6W563	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:baba2_human(display_long)|uniprotkb:BABAM2(gene name)|psi-mi:BABAM2(display_short)|uniprotkb:BRCA1-A complex subunit BRE(gene name synonym)|uniprotkb:BRCA1/BRCA2-containing complex subunit 45(gene name synonym)|uniprotkb:BRCC45(gene name synonym)|uniprotkb:BRE(gene name synonym)|uniprotkb:Brain and reproductive organ-expressed protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000158019(gene)|ensembl:ENST00000342045(transcript)|ensembl:ENST00000379624(transcript)|go:"GO:0000152"(nuclear ubiquitin ligase complex)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051301"(cell division)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|interpro:IPR010358(Brain and reproductive organ-expressed)|rcsb pdb:6H3C|rcsb pdb:6R8F|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|go:"GO:0006302"(double-strand break repair)|refseq:NP_004890.2|refseq:NP_954661.1|refseq:NP_954662.1|refseq:NP_954663.1|refseq:NP_954664.1|refseq:NP_001248769.1|refseq:NP_001316041.1|refseq:NP_001316042.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:ULbrw0O7e5M0Hzho3d05OlUnEGM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15365	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q96CS3	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P51665	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9H4B7	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2949748|ensembl:ENSP00000217133	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tbb1_human(display_long)|uniprotkb:TUBB1(gene name)|psi-mi:TUBB1(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000101162(gene)|ensembl:ENST00000217133(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0051225"(spindle assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9H4B7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-983189|reactome:R-HSA-9668328|refseq:NP_110400.1|dip:DIP-42487N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:6bCGUsGUoUdlvvDkLH2G+2V3cdc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P35606	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1056534|uniprotkb:B4DZI8|intact:EBI-11019844|ensembl:ENSP00000329419	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:copb2_human(display_long)|uniprotkb:COPB2(gene name)|psi-mi:COPB2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:p102(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004757.1|ensembl:ENSG00000184432(gene)|ensembl:ENST00000333188(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:1901998"(toxin transport)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|mint:P35606|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_016863001.1|dip:DIP-27603N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:zkd7lOeV+OvHglnAJg6cXoMhgbg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q08211	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q7L576	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1048143|uniprotkb:Q14467|uniprotkb:Q5IED0|uniprotkb:Q6ZSX1|uniprotkb:Q9BSD9|uniprotkb:Q9BVC7|uniprotkb:A8K6D9|ensembl:ENSP00000478779|ensembl:ENSP00000481038|ensembl:ENSP00000499947|ensembl:ENSP00000500331	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cyfp1_human(display_long)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym)|uniprotkb:p140sra-1(gene name synonym)|uniprotkb:CYFIP1(gene name)|psi-mi:CYFIP1(display_short)|uniprotkb:KIAA0068(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001028200.1|refseq:NP_055423.1|refseq:NP_001274739.1|ensembl:ENSG00000273749(gene)|ensembl:ENSG00000288461(gene)|ensembl:ENST00000610365(transcript)|ensembl:ENST00000617928(transcript)|ensembl:ENST00000671714(transcript)|ensembl:ENST00000672091(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0006417"(regulation of translation)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031209"(SCAR complex)|go:"GO:0005576"(extracellular region)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032433"(filopodium tip)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0005829"(cytosol)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050890"(cognition)|go:"GO:0051015"(actin filament binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060076"(excitatory synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090724"(central region of growth cone)|go:"GO:0090725"(peripheral region of growth cone)|go:"GO:0097484"(dendrite extension)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1903422"(negative regulation of synaptic vesicle recycling)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q7L576|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001311049.1|refseq:NP_001311052.1|dip:DIP-38873N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:cEF+RA9JRXz8Mbsl/s89Up2ONRc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q12931	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1055869|uniprotkb:O43642|uniprotkb:O75235|uniprotkb:Q9UHL5|uniprotkb:B4DR68|uniprotkb:F5H897|uniprotkb:D3DUC8|ensembl:ENSP00000246957	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:trap1_human(display_long)|uniprotkb:TRAP1(gene name)|psi-mi:TRAP1(display_short)|uniprotkb:HSP75(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_057376.2|refseq:NP_001258978.1|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q12931|rcsb pdb:4Z1F|rcsb pdb:4Z1G|rcsb pdb:4Z1H|rcsb pdb:4Z1I|rcsb pdb:5F3K|rcsb pdb:5F5R|rcsb pdb:5HPH|rcsb pdb:5Y3N|rcsb pdb:5Y3O|rcsb pdb:6XG6|rcsb pdb:7C04|rcsb pdb:7C05|rcsb pdb:7C7B|rcsb pdb:7C7C|reactome:R-HSA-611105|ensembl:ENSG00000126602(gene)|ensembl:ENST00000246957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|dip:DIP-6250N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:O/i+7vgZQcDQF3xJTeqNLbWiQ8U9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q14568	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2826582	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:hs902_human(display_long)|uniprotkb:HSP90AA2P(gene name)|psi-mi:HSP90AA2P(display_short)|uniprotkb:HSP90AA2(gene name synonym)|uniprotkb:HSPCAL3(gene name synonym)|uniprotkb:Heat shock 90 kDa protein 1 alpha-like 3(gene name synonym)|uniprotkb:Heat shock protein HSP 90-alpha A2 pseudogene(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR036890|mint:Q14568	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:HN+Hui0dI60DoXKDmTqZRgIEyK49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q96QK1	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:EXkMduDQKNCdp876vGF5vna9t389606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q12965	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-4279548|uniprotkb:Q14778|ensembl:ENSP00000288235	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:myo1e_human(display_long)|uniprotkb:Myosin-Ic(gene name synonym)|uniprotkb:MYO1E(gene name)|psi-mi:MYO1E(display_short)|uniprotkb:MYO1C(gene name synonym)|uniprotkb:Unconventional myosin 1E(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004989.2|ensembl:ENSG00000157483(gene)|ensembl:ENST00000288235(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035507|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|mint:Q12965|ensembl:ENSP00000288235|dip:DIP-884N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:UyG3wKoRwL2Eaw9CM6561vld+PU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P28331	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q92974	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-302405|intact:EBI-1045693|uniprotkb:O75142|uniprotkb:Q15079|uniprotkb:Q5VY92|uniprotkb:Q8TDA3|uniprotkb:Q8WUG4|uniprotkb:Q9H023|ensembl:ENSP00000354837|uniprotkb:D3DVA6	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:arhg2_human(display_long)|uniprotkb:ARHGEF2(gene name)|psi-mi:ARHGEF2(display_short)|uniprotkb:KIAA0651(gene name synonym)|uniprotkb:LFP40(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor H1(gene name synonym)|uniprotkb:Microtubule-regulated Rho-GEF(gene name synonym)|uniprotkb:Proliferating cell nucleolar antigen p40(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001155855.1|refseq:NP_001155856.1|refseq:NP_004714.2|ensembl:ENSG00000116584(gene)|ensembl:ENST00000361247(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR037806|interpro:IPR041020|mint:Q92974|rcsb pdb:5EFX|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045087"(innate immune response)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:GljUl7uzMi3HaFQsMybfT6KrW089606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P10809	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P04899	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-353997|uniprotkb:Q8IZ71|intact:EBI-2563889|uniprotkb:B4DYA0|intact:EBI-4404691|uniprotkb:Q6B6N3|uniprotkb:B3KTZ0|uniprotkb:B4E2X5|ensembl:ENSP00000312999	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:gnai2_human(display_long)|uniprotkb:GNAI2(gene name)|psi-mi:GNAI2(display_short)|uniprotkb:GNAI2B(gene name synonym)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002061.1|refseq:NP_001269546.1|refseq:NP_001269549.1|refseq:NP_001269547.1|refseq:NP_001269548.1|refseq:NP_001159897.1|dip:DIP-602N|ensembl:ENSG00000114353(gene)|ensembl:ENST00000313601(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:0030425"(dendrite)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6D9H|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|mint:P04899	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Mi3PAXudkdPb375bOi7luNAmUaU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9H2U2	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-3957115|uniprotkb:B4DLP7|uniprotkb:Q4W5E9|uniprotkb:Q6PG51|uniprotkb:Q8TBW0|uniprotkb:Q96E55|uniprotkb:Q9H0T0|uniprotkb:Q9NX37|uniprotkb:Q9P033|uniprotkb:Q9ULX0|uniprotkb:I6L9B6|uniprotkb:F8WDN9|ensembl:ENSP00000343885	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ipyr2_human(display_long)|uniprotkb:PPA2(gene name)|psi-mi:PPA2(display_short)|uniprotkb:Pyrophosphatase SID6-306(gene name synonym)|uniprotkb:Pyrophosphate phospho-hydrolase 2(gene name synonym)|uniprotkb:HSPC124(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_008834.3|refseq:NP_789842.2|refseq:NP_789843.2|refseq:NP_789845.1|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0071344"(diphosphate metabolic process)|interpro:IPR008162(Inorganic pyrophosphatase)|interpro:IPR036649|mint:Q9H2U2|reactome:R-HSA-379726|reactome:R-HSA-71737|ensembl:ENSG00000138777(gene)|ensembl:ENST00000341695(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004427"(inorganic diphosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:KrPc55Mf6MjN5tgxFagI03miOwY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P36873	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356283|ensembl:ENSP00000335084	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15084	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1043087|uniprotkb:Q6ZSH5|ensembl:ENSP00000272227|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|interpro:IPR036249|interpro:IPR044569|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|interpro:IPR017937|ensembl:ENSG00000143870(gene)|ensembl:ENST00000272227(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005733.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:411bo7TdfeCtMvUqyBb7bofi5To9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O43813	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-3046631|ensembl:ENSP00000233714|ensembl:ENSP00000388713|ensembl:ENSP00000393323|ensembl:ENSP00000393597|ensembl:ENSP00000397646	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:lanc1_human(display_long)|uniprotkb:LANCL1(gene name)|psi-mi:LANCL1(display_short)|uniprotkb:GPR69A(gene name synonym)|uniprotkb:40 kDa erythrocyte membrane protein(gene name synonym)|uniprotkb:LanC-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000115365(gene)|ensembl:ENST00000233714(transcript)|ensembl:ENST00000431941(transcript)|ensembl:ENST00000441020(transcript)|ensembl:ENST00000443314(transcript)|ensembl:ENST00000450366(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043295"(glutathione binding)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:1903203"(regulation of oxidative stress-induced neuron death)|interpro:IPR007822(Lanthionine synthetase C-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR020464|mint:O43813|rcsb pdb:3E6U|rcsb pdb:3E73|refseq:NP_001130046.1|refseq:NP_001130047.1|refseq:NP_006046.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:em3J/MvBGB1LZ0X1QFagwWBk5FQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q14289	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-298640|uniprotkb:Q13475|uniprotkb:Q14290|uniprotkb:Q16709|intact:EBI-2211226|uniprotkb:Q6PID4|ensembl:ENSP00000332816|ensembl:ENSP00000380638|uniprotkb:D3DST0	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:fak2_human(display_long)|uniprotkb:PTK2B(gene name)|psi-mi:PTK2B(display_short)|uniprotkb:FAK2(gene name synonym)|uniprotkb:PYK2(gene name synonym)|uniprotkb:RAFTK(gene name synonym)|uniprotkb:Focal adhesion kinase 2(gene name synonym)|uniprotkb:Proline-rich tyrosine kinase 2(gene name synonym)|uniprotkb:Cell adhesion kinase beta(gene name synonym)|uniprotkb:Calcium-dependent tyrosine kinase(gene name synonym)|uniprotkb:Related adhesion focal tyrosine kinase(gene name synonym)|uniprotkb:Calcium-regulated non-receptor proline-rich tyrosine kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004094.3|refseq:NP_775266.1|refseq:NP_775267.1|refseq:NP_775268.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032960"(regulation of inositol trisphosphate biosynthetic process)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006968"(cellular defense response)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051591"(response to cAMP)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097440"(apical dendrite)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR020635|interpro:IPR029071|interpro:IPR030610|interpro:IPR035963|interpro:IPR036137|interpro:IPR041390|interpro:IPR041784|rcsb pdb:2FO6|rcsb pdb:2LK4|rcsb pdb:3CC6|rcsb pdb:3ET7|rcsb pdb:3FZO|rcsb pdb:3FZP|rcsb pdb:3FZR|rcsb pdb:3FZS|rcsb pdb:3FZT|rcsb pdb:3GM1|rcsb pdb:3GM2|rcsb pdb:3GM3|rcsb pdb:3H3C|rcsb pdb:3U3F|rcsb pdb:4EKU|rcsb pdb:4H1J|rcsb pdb:4H1M|rcsb pdb:4R32|rcsb pdb:4XEF|rcsb pdb:4XEK|rcsb pdb:4XEV|rcsb pdb:5TO8|rcsb pdb:5TOB|rcsb pdb:6LF3|reactome:R-HSA-391160|reactome:R-HSA-4420097|reactome:R-HSA-9020558|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043423"(3-phosphoinositide-dependent protein kinase binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0045453"(bone resorption)|go:"GO:0045471"(response to ethanol)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000538"(positive regulation of B cell chemotaxis)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009725"(response to hormone)|go:"GO:0009749"(response to glucose)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010752"(regulation of cGMP-mediated signaling)|go:"GO:0010758"(regulation of macrophage chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|ensembl:ENSG00000120899(gene)|ensembl:ENST00000346049(transcript)|ensembl:ENST00000397501(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001525"(angiogenesis)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002250"(adaptive immune response)|refseq:XP_011542743.1|refseq:XP_005273504.1|refseq:XP_016868703.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:rpqjaDBbtx7BK+JiIR/sBlyPLvY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O43684	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1050987|uniprotkb:O43685|uniprotkb:B2R6E7|uniprotkb:A6NJ42|uniprotkb:D3DRE9|ensembl:ENSP00000357858	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:bub3_human(display_long)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001007794.1|refseq:NP_004716.1|ensembl:ENSG00000154473(gene)|ensembl:ENST00000368865(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR020472|interpro:IPR036322|mint:O43684|reactome:R-HSA-141430|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|dip:DIP-24205N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:nqzARPql2cThSUpxSb6PuTRn51E9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q8WU76	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2561361|ensembl:ENSP00000384182|uniprotkb:Q8N5F3|uniprotkb:Q96ED3|uniprotkb:Q8N8H0	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:scfd2_human(display_long)|uniprotkb:SCFD2(gene name)|psi-mi:SCFD2(display_short)|uniprotkb:STXBP1L1(gene name synonym)|uniprotkb:Syntaxin-binding protein 1-like 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000184178(gene)|ensembl:ENST00000401642(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|refseq:NP_689753.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:TaNn58iCMGPAhs6k76eLY0BuGKM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q3ZCM7	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-302558|ensembl:ENSP00000456206|intact:EBI-1390656|uniprotkb:Q5SQX9|uniprotkb:Q8WZ78	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tbb8_human(display_long)|uniprotkb:TUBB8(gene name)|psi-mi:TUBB8(display_short)|uniprotkb:Tubulin beta 8 class VIII(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9619483|ensembl:ENSG00000261456(gene)|ensembl:ENST00000568584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072687"(meiotic spindle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q3ZCM7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|refseq:NP_817124.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:bTJnhl0qEm2ACoHQ7IOcn5Rx7xM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14773	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O00160	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-741792|uniprotkb:Q8WWN7|ensembl:ENSP00000481682|ensembl:ENSP00000494550	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:myo1f_human(display_long)|uniprotkb:Myosin-Ie(gene name synonym)|uniprotkb:MYO1F(gene name)|psi-mi:MYO1F(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_036467.2|ensembl:ENSG00000142347(gene)|ensembl:ENST00000613525(transcript)|ensembl:ENST00000644032(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035507|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:k11A+oPM3i3NjaFa80A73soCqCE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O43390	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P45880	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-354022|ensembl:ENSP00000361686|ensembl:ENSP00000443092|uniprotkb:Q5VWK1|uniprotkb:Q5VWK3|uniprotkb:Q6IB40|uniprotkb:Q7L3J5|uniprotkb:Q9BWK8|uniprotkb:Q9Y5I6	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:vdac2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000165637(gene)|ensembl:ENST00000332211(transcript)|ensembl:ENST00000543351(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|refseq:NP_001171712.1|refseq:NP_001171752.1|refseq:NP_003366.2|refseq:NP_001311017.1|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:P45880|reactome:R-HSA-5689880|reactome:R-HSA-8949215	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:seQxCd19Z2HmpXcwb48osAuuafA9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P35626	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2875868|ensembl:ENSP00000317578|uniprotkb:Q9UGW9	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:arbk2_human(display_long)|uniprotkb:GRK3(gene name)|psi-mi:GRK3(display_short)|uniprotkb:ADRBK2(gene name synonym)|uniprotkb:BARK2(gene name synonym)|uniprotkb:G-protein-coupled receptor kinase 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0031623"(receptor internalization)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0005886"(plasma membrane)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|reactome:R-HSA-418555|reactome:R-HSA-8856825|ensembl:ENSG00000100077(gene)|ensembl:ENST00000324198(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|refseq:NP_005151.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:IXh7IeKOJ35sBT4TzFHPNB1xhnE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q96P70	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P62140	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P08754	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357563|uniprotkb:Q5TZX1|uniprotkb:P17539|ensembl:ENSP00000358867	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:gnai3_human(display_long)|uniprotkb:GNAI3(gene name)|psi-mi:GNAI3(display_short)|uniprotkb:"G(i) alpha-3"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006487.1|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|ensembl:ENSG00000065135(gene)|ensembl:ENST00000369851(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007049"(cell cycle)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0042588"(zymogen granule)|go:"GO:0045121"(membrane raft)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:2IHB|rcsb pdb:2ODE|rcsb pdb:2V4Z|rcsb pdb:4G5O|rcsb pdb:4G5R|rcsb pdb:4G5S|rcsb pdb:7E9H|rcsb pdb:7KH0|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-9009391|reactome:R-HSA-9660821	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:npLeIXVzrV8y0trCCII5rivIRYQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P41252	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355303|uniprotkb:Q5TCD0|uniprotkb:Q9H588|uniprotkb:A8KAE9|uniprotkb:Q7Z3T4|ensembl:ENSP00000364794|ensembl:ENSP00000406448|ensembl:ENSP00000507144	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:syic_human(display_long)|uniprotkb:IARS1(gene name)|psi-mi:IARS1(display_short)|uniprotkb:IARS(gene name synonym)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002152.2|refseq:NP_038203.2|ensembl:ENSG00000196305(gene)|ensembl:ENST00000375643(transcript)|ensembl:ENST00000443024(transcript)|ensembl:ENST00000683565(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023586|interpro:IPR033709|mint:P41252|reactome:R-HSA-2408522|reactome:R-HSA-379716	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:maAJX/O1Ryxr5NVFQEWvXNgHXyY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q8WUM4	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P49327	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q05193	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-713135|uniprotkb:A6NLM6|uniprotkb:Q5SYX0|uniprotkb:Q5SYX2|uniprotkb:Q6P3T6|uniprotkb:Q86VD2|ensembl:ENSP00000362014	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dyn1_human(display_long)|uniprotkb:DNM1(gene name)|psi-mi:DNM1(display_short)|uniprotkb:DNM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001005336.1|refseq:NP_004399.2|refseq:NP_001275666.1|refseq:NP_001275667.1|refseq:NP_001275668.1|refseq:XP_005251825.1|refseq:XP_005251826.1|refseq:XP_016869860.1|dip:DIP-36242N|ensembl:ENSG00000106976(gene)|ensembl:ENST00000372923(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:Q05193|rcsb pdb:1DYN|rcsb pdb:2DYN|rcsb pdb:2X2E|rcsb pdb:2X2F|rcsb pdb:3SNH|rcsb pdb:3ZYC|rcsb pdb:3ZYS|rcsb pdb:4UUD|rcsb pdb:4UUK|rcsb pdb:5D3Q|rcsb pdb:6DLU|rcsb pdb:6DLV|rcsb pdb:6S9A|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-437239|reactome:R-HSA-8856828|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:uiP8CXhKWQaP2GIAZULJTLqwGLs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9Y282	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-781551|uniprotkb:Q6ZWP7|uniprotkb:Q9H276|uniprotkb:Q9P1L3|uniprotkb:Q5JWS3|ensembl:ENSP00000341358	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ergi3_human(display_long)|uniprotkb:Serologically defined breast cancer antigen NY-BR-84(gene name synonym)|uniprotkb:ERGIC3(gene name)|psi-mi:ERGIC3(display_short)|uniprotkb:C20orf47(gene name synonym)|uniprotkb:CGI-54(orf name)|uniprotkb:PRO0989(orf name)|uniprotkb:ERV46(gene name synonym)|uniprotkb:SDBCAG84(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_057050.1|refseq:NP_938408.1|ensembl:ENSG00000125991(gene)|ensembl:ENST00000348547(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|mint:Q9Y282	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:LllzE6k0eaM1uUJGjkieiPARw149606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9Y6N5	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1170418|uniprotkb:Q9UQM8|ensembl:ENSP00000260324|ensembl:ENSP00000456019	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sqor_human(display_long)|uniprotkb:SQOR(gene name)|psi-mi:SQOR(display_short)|uniprotkb:SQRDL(gene name synonym)|uniprotkb:Sulfide quinone oxidoreductase(gene name synonym)|uniprotkb:CGI-44(orf name)|uniprotkb:Sulfide dehydrogenase-like(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_067022.1|refseq:NP_001258142.1|ensembl:ENSG00000137767(gene)|ensembl:ENST00000260324(transcript)|ensembl:ENST00000568606(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0048038"(quinone binding)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0070224"("sulfide:quinone oxidoreductase activity")|go:"GO:0070813"(hydrogen sulfide metabolic process)|go:"GO:0071949"(FAD binding)|interpro:IPR015904(Sulphide quinone-reductase)|interpro:IPR023753|interpro:IPR036188|mint:Q9Y6N5|rcsb pdb:6MO6|rcsb pdb:6MP5|rcsb pdb:6OI5|rcsb pdb:6OI6|rcsb pdb:6OIB|rcsb pdb:6OIC|rcsb pdb:6WH6|reactome:R-HSA-1614517	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:bjOY0YAzon+joBQnCx3q9YvSHh49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O94808	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916534|ensembl:ENSP00000253778|uniprotkb:Q53XM2|uniprotkb:Q9BWS4	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:gfpt2_human(display_long)|uniprotkb:GFPT2(gene name)|psi-mi:GFPT2(display_short)|uniprotkb:D-fructose-6-phosphate amidotransferase 2(gene name synonym)|uniprotkb:"Glutamine:fructose-6-phosphate amidotransferase 2"(gene name synonym)|uniprotkb:Hexosephosphate aminotransferase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000131459(gene)|ensembl:ENST00000253778(transcript)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR017932|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490|reactome:R-HSA-446210|refseq:NP_005101.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:e0qXUjWfS1KMkEBSEES+IgoPnLI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9Y4W6	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000141385(gene)|ensembl:ENST00000269143(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|refseq:NP_006787.2|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9NZ01	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2877718|ensembl:ENSP00000215567|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000099797(gene)|ensembl:ENST00000215567(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_612510.1|refseq:NP_001308099.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P22314	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14734	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1237371|uniprotkb:O15261|uniprotkb:Q17RX4|ensembl:ENSP00000217455	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:acot8_human(display_long)|uniprotkb:ACOT8(gene name)|psi-mi:ACOT8(display_short)|uniprotkb:ACTEIII(gene name synonym)|uniprotkb:PTE1(gene name synonym)|uniprotkb:Choloyl-coenzyme A thioesterase(gene name synonym)|uniprotkb:Peroxisomal acyl-coenzyme A thioester hydrolase 1(gene name synonym)|uniprotkb:Peroxisomal long-chain acyl-CoA thioesterase 1(gene name synonym)|uniprotkb:HIV-Nef-associated acyl-CoA thioesterase(gene name synonym)|uniprotkb:Thioesterase II(gene name synonym)|uniprotkb:Peroxisomal acyl-CoA thioesterase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005460.2|dip:DIP-38179N|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0043649"(dicarboxylic acid catabolic process)|go:"GO:0044466"(glutaryl-CoA hydrolase activity)|go:"GO:0045225"(negative regulation of CD4 production)|go:"GO:0047603"(acetoacetyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0047994"(hydroxymethylglutaryl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0052815"(medium-chain acyl-CoA hydrolase activity)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|interpro:IPR003703(Acyl-CoA thioesterase)|interpro:IPR029069|interpro:IPR042171|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|ensembl:ENSG00000101473(gene)|ensembl:ENST00000217455(transcript)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0004778"(succinyl-CoA hydrolase activity)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016289"(CoA hydrolase activity)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0016559"(peroxisome fission)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0033882"(choloyl-CoA hydrolase activity)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Q8Y3l4ysgKPMi3mJU2/g8mVxWE09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14828	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-4401333|ensembl:ENSP00000307275|ensembl:ENSP00000461521|uniprotkb:A9Z1W6|uniprotkb:B1AVS6|uniprotkb:O15128|uniprotkb:Q96FR8|uniprotkb:Q9BPY0	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:scam3_human(display_long)|uniprotkb:SCAMP3(gene name)|psi-mi:SCAMP3(display_short)|uniprotkb:C1orf3(gene name synonym)|uniprotkb:PROPIN1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000116521(gene)|ensembl:ENSG00000263290(gene)|ensembl:ENST00000302631(transcript)|ensembl:ENST00000570831(transcript)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007273(SCAMP)|mint:O14828|ensembl:ENSP00000307275|ensembl:ENST00000355379|ensembl:ENSP00000347540|ensembl:ENSP00000461521|ensembl:ENST00000573013|ensembl:ENSP00000458542|refseq:NP_005689.2|refseq:NP_443069.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:q1GaoVa7cLS2hGHVUM5Nv2oX4x09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q13426	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-717592|uniprotkb:Q9BS72|uniprotkb:Q9UP94|uniprotkb:A8K3X4|ensembl:ENSP00000342011|ensembl:ENSP00000421491	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:xrcc4_human(display_long)|uniprotkb:X-ray repair cross-complementing protein 4(gene name synonym)|uniprotkb:XRCC4(gene name)|psi-mi:XRCC4(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003392.1|refseq:NP_071801.1|refseq:NP_072044.1|refseq:NP_001304941.1|refseq:NP_001304942.1|refseq:XP_011541928.1|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010165"(response to X-ray)|go:"GO:0032807"(DNA ligase IV complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0070975"(FHA domain binding)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1990166"(protein localization to site of double-strand break)|interpro:IPR009089(DNA double-strand break repair and VJ recombination XRCC4, N-terminal)|interpro:IPR010585(DNA double-strand break repair and VJ recombination XRCC4)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR038051|mint:Q13426|rcsb pdb:1FU1|rcsb pdb:1IK9|rcsb pdb:3II6|rcsb pdb:3MUD|rcsb pdb:3Q4F|rcsb pdb:3RWR|rcsb pdb:3SR2|go:"GO:0005737"(cytoplasm)|rcsb pdb:3W03|rcsb pdb:4XA4|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ4|rcsb pdb:5E50|rcsb pdb:5WJ7|rcsb pdb:5WLZ|rcsb pdb:6ABO|rcsb pdb:7LSY|rcsb pdb:7LT3|rcsb pdb:7M3P|reactome:R-HSA-164843|reactome:R-HSA-3108214|reactome:R-HSA-5693571|ensembl:ENSG00000152422(gene)|ensembl:ENST00000338635(transcript)|ensembl:ENST00000511817(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-37957N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:qWdX2yBKXcwYG7vQpss9MIaFWU89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q13561	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-715074|uniprotkb:Q86YN2|uniprotkb:Q9BW17|uniprotkb:B2RBK5|ensembl:ENSP00000447824	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dctn2_human(display_long)|uniprotkb:Dynactin complex 50 kDa subunit(gene name synonym)|uniprotkb:50 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:p50 dynamitin(gene name synonym)|uniprotkb:DCTN2(gene name)|psi-mi:DCTN2(display_short)|uniprotkb:DCTN50(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006391.1|refseq:NP_001248341.1|refseq:NP_001248342.1|dip:DIP-37545N|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|ensembl:ENSG00000175203(gene)|ensembl:ENST00000548249(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030426"(growth cone)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0032402"(melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR028133|mint:Q13561|reactome:R-HSA-2132295	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:JrL5jUtArek+zqmCkPKomnjuSf09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P26640	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355765|uniprotkb:Q5JQ90|uniprotkb:Q96E77|uniprotkb:Q9UQM2|uniprotkb:B4DZ61|uniprotkb:B0V1N1|ensembl:ENSP00000211402|ensembl:ENSP00000364815|ensembl:ENSP00000401121|ensembl:ENSP00000403359|ensembl:ENSP00000415316	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:syvc_human(display_long)|uniprotkb:VARS1(gene name)|psi-mi:VARS1(display_short)|uniprotkb:G7A(gene name synonym)|uniprotkb:Protein G7a(gene name synonym)|uniprotkb:VARS(gene name synonym)|uniprotkb:VARS2(gene name synonym)|uniprotkb:Valyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006286.1|ensembl:ENSG00000096171(gene)|ensembl:ENSG00000204394(gene)|ensembl:ENSG00000224264(gene)|ensembl:ENSG00000226589(gene)|ensembl:ENSG00000231116(gene)|ensembl:ENST00000211402(transcript)|ensembl:ENST00000375663(transcript)|ensembl:ENST00000422694(transcript)|ensembl:ENST00000435657(transcript)|ensembl:ENST00000457796(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004832"(valine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006438"(valyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033705|interpro:IPR036282|interpro:IPR037118|mint:P26640|reactome:R-HSA-379716	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:aPfpK0/C2KpCsMOI0sjCreufI509606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P52907	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q96KG9	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-949287|intact:EBI-28972634|ensembl:ENSP00000270176|uniprotkb:A6NJF1|uniprotkb:Q96G50|uniprotkb:Q96KG8|uniprotkb:Q96KH1|uniprotkb:Q9HAW5|uniprotkb:Q9HBL3|uniprotkb:Q9NR53	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:scyl1_human(display_long)|uniprotkb:SCY1-like protein 1(gene name synonym)|uniprotkb:Teratoma-associated tyrosine kinase(gene name synonym)|uniprotkb:Telomerase transcriptional element-interacting factor(gene name synonym)|uniprotkb:Telomerase regulation-associated protein(gene name synonym)|uniprotkb:SCYL1(gene name)|psi-mi:SCYL1(display_short)|uniprotkb:Coated vesicle-associated kinase of 90 kDa(gene name synonym)|uniprotkb:CVAK90(gene name synonym)|uniprotkb:GKLP(gene name synonym)|uniprotkb:NTKL(gene name synonym)|uniprotkb:TAPK(gene name synonym)|uniprotkb:TEIF(gene name synonym)|uniprotkb:TRAP(gene name synonym)|uniprotkb:HT019(orf name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000142186(gene)|ensembl:ENST00000270176(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0048666"(neuron development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001041683.1|refseq:NP_065731.3|ensembl:ENSP00000270176|ensembl:ENST00000420247|ensembl:ENSP00000408192|ensembl:ENST00000533862|ensembl:ENSP00000437254|refseq:XP_005274177.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:qHL7to7M3sjqepd3yuU1uo4Mhy49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9H0C8	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2620298|uniprotkb:B3KM39|ensembl:ENSP00000254654	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ilkap_human(display_long)|uniprotkb:ILKAP(gene name)|psi-mi:ILKAP(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_110395.1|ensembl:ENSG00000132323(gene)|ensembl:ENST00000254654(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q9H0C8	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:iKH8FvITcNnqKYK8zIsijGhZllM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9Y678	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1049127|uniprotkb:A8K6M8|uniprotkb:B3KMF6|uniprotkb:Q54AC4|ensembl:ENSP00000325002	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:copg1_human(display_long)|uniprotkb:COPG1(gene name)|psi-mi:COPG1(display_short)|uniprotkb:COPG(gene name synonym)|uniprotkb:Gamma-1-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_057212.1|ensembl:ENSG00000181789(gene)|ensembl:ENST00000314797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9Y678|rcsb pdb:1R4X|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29872N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:P3wujl1rJH+o0vUUl/rLp0PEpMU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14579	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-711301|uniprotkb:O76097|ensembl:ENSP00000262812|uniprotkb:Q9UGP6|uniprotkb:Q6IBB8|uniprotkb:A6NKA3|uniprotkb:A6NE29	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cope_human(display_long)|uniprotkb:COPE(gene name)|psi-mi:COPE(display_short)|uniprotkb:Epsilon-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_009194.2|ensembl:ENSG00000105669(gene)|ensembl:ENST00000262812(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:O14579|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_955474.1|refseq:NP_955476.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:gjrR0x7iNHl/nEDtoZTjThB1dgs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q8N163	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O95352	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-987834|uniprotkb:Q7L8L0|uniprotkb:Q9BWP2|uniprotkb:Q9UFH4|ensembl:ENSP00000346437|uniprotkb:B4E170|uniprotkb:E9PB95	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:atg7_human(display_long)|uniprotkb:ATG12-activating enzyme E1 ATG7(gene name synonym)|uniprotkb:Ubiquitin-activating enzyme E1-like protein(gene name synonym)|uniprotkb:ATG7(gene name)|psi-mi:ATG7(display_short)|uniprotkb:APG7L(gene name synonym)|uniprotkb:Autophagy-related protein 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000197548(gene)|ensembl:ENST00000354449(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006497"(protein lipidation)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009749"(response to glucose)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019778"(Atg12 activating enzyme activity)|go:"GO:0019779"(Atg8 activating enzyme activity)|go:"GO:0030424"(axon)|go:"GO:0031401"(positive regulation of protein modification process)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|interpro:IPR035985|interpro:IPR042522|go:"GO:0034774"(secretory granule lumen)|interpro:IPR042523|reactome:R-HSA-1632852|reactome:R-HSA-6798695|reactome:R-HSA-6802952|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0071315"(cellular response to morphine)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0090298"(negative regulation of mitochondrial DNA replication)|go:"GO:1902617"(response to fluoride)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR006285(E1-like protein-activating enzyme Gsa7p/Apg7p)|interpro:IPR032197|reactome:R-HSA-983168|refseq:XP_011531584.1|refseq:XP_011531588.1|refseq:NP_001129503.2|refseq:NP_001138384.1|refseq:NP_006386.1|refseq:XP_016861033.1|refseq:XP_016861034.1|refseq:XP_016861035.1|dip:DIP-29759N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:myjul9H3gvlZOK/NURXIkmjXspU9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O43592	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-286683|uniprotkb:A6NLH1|uniprotkb:O43784|uniprotkb:Q8WUG2|uniprotkb:Q9BVS7|ensembl:ENSP00000327821	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:xpot_human(display_long)|uniprotkb:tRNA exportin(gene name synonym)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:XPOT(gene name)|psi-mi:XPOT(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_009166.2|refseq:XP_016874237.1|ensembl:ENSG00000184575(gene)|ensembl:ENST00000332707(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017|mint:O43592|reactome:R-HSA-6784531	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:S0p7em6zWNUHEuAYueP+ZTrKTKg9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P50452	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6916752|uniprotkb:B4DTW2|uniprotkb:Q7Z2V6|uniprotkb:Q8N178|ensembl:ENSP00000331368|ensembl:ENSP00000381072	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:spb8_human(display_long)|uniprotkb:SERPINB8(gene name)|psi-mi:SERPINB8(display_short)|uniprotkb:PI8(gene name synonym)|uniprotkb:Cytoplasmic antiproteinase 2(gene name synonym)|uniprotkb:Peptidase inhibitor 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001027018.1|refseq:NP_001263419.1|refseq:NP_002631.3|refseq:NP_942130.1|ensembl:ENSG00000166401(gene)|ensembl:ENST00000353706(transcript)|ensembl:ENST00000397985(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|reactome:R-HSA-75205	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:8zDKTATO2nW9OagEjG5BmtJcRxQ9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P55072	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O75477	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P50570	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q03113	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2833081|uniprotkb:Q2T9L1|uniprotkb:Q8TD71|uniprotkb:Q86UM8|uniprotkb:Q9UDU9|uniprotkb:A4D204|ensembl:ENSP00000275364|uniprotkb:B3KXS2|uniprotkb:B7Z3F7|uniprotkb:Q5PPR5	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:gna12_human(display_long)|uniprotkb:GNA12(gene name)|psi-mi:GNA12(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001280021.1|ensembl:ENSG00000146535(gene)|ensembl:ENST00000275364(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031752"(D5 dopamine receptor binding)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:Q03113|reactome:R-HSA-416482|reactome:R-HSA-456926|refseq:NP_031379.2|refseq:NP_001269370.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:iuIDldvBlG+r+jg59e3QSNbcvtY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P55263	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1384340|uniprotkb:B7Z800|uniprotkb:O00741|uniprotkb:O00742|uniprotkb:Q16710|uniprotkb:Q9BTN2|uniprotkb:Q5JQ11|uniprotkb:B7Z783|uniprotkb:Q5JQ10|ensembl:ENSP00000443965	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:adk_human(display_long)|uniprotkb:Adenosine 5'-phosphotransferase(gene name synonym)|uniprotkb:ADK(gene name)|psi-mi:ADK(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001114.2|refseq:NP_001189378.1|refseq:NP_006712.2|refseq:NP_001189379.1|ensembl:ENSG00000156110(gene)|ensembl:ENST00000539909(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004001"(adenosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006175"(dATP biosynthetic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0044209"(AMP salvage)|go:"GO:0046872"(metal ion binding)|interpro:IPR001805(Adenosine kinase)|interpro:IPR002173(Carbohydrate/puine kinase, PfkB, conserved site)|interpro:IPR011611(Carbohydrate/purine kinase)|interpro:IPR029056|rcsb pdb:1BX4|rcsb pdb:2I6A|rcsb pdb:2I6B|rcsb pdb:4O1L|reactome:R-HSA-74217|go:"GO:0006166"(purine ribonucleoside salvage)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:YiapVEW3Fq83fwNLkIwwnJxFYzE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15437	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:+3KZ/1jjziSgJRcr81Axquofkl49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:A6NHL2	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-2954795|uniprotkb:Q9H6Z0|uniprotkb:Q4QQJ5|uniprotkb:B4DKL2|ensembl:ENSP00000369784	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tbal3_human(display_long)|uniprotkb:TUBAL3(gene name)|psi-mi:TUBAL3(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001165335.1|refseq:NP_079079.1|ensembl:ENSG00000178462(gene)|ensembl:ENST00000380419(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Yr8HihP2hK6YdLc8Xa9edSOOrA09606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q16531	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9UNM6	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-356070|uniprotkb:O75831|uniprotkb:Q9UNV3|uniprotkb:Q53XU2|intact:EBI-1058479|uniprotkb:B3KT15|ensembl:ENSP00000436186	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:psd13_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002808.3|refseq:NP_787128.2|dip:DIP-27576N|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:6MSK|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000185627(gene)|ensembl:ENST00000532097(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007127"(meiosis I)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|mint:Q9UNM6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:iOxE62MMeGx+aqsrir/LukJqeho9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P13798	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-723792|ensembl:ENSP00000296456|uniprotkb:Q9BQ33|uniprotkb:Q9P0Y2	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:acph_human(display_long)|uniprotkb:Acyl-peptide hydrolase(gene name synonym)|uniprotkb:Acylaminoacyl-peptidase(gene name synonym)|uniprotkb:Oxidized protein hydrolase(gene name synonym)|uniprotkb:APEH(gene name)|psi-mi:APEH(display_short)|uniprotkb:D3F15S2(gene name synonym)|uniprotkb:D3S48E(gene name synonym)|uniprotkb:DNF15S2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011531962.1|refseq:NP_001631.3|ensembl:ENSG00000164062(gene)|ensembl:ENST00000296456(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0006415"(translational termination)|go:"GO:0006508"(proteolysis)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002471(Peptidase S9, serine active site)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR029058|reactome:R-HSA-6798695|reactome:R-HSA-72764	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:vkyLSLi3WpS01GRu7YwDpq+yMsI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q15029	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-357897|uniprotkb:Q9BUR0|uniprotkb:D3DX58|uniprotkb:B4DK30|ensembl:ENSP00000392094|ensembl:ENSP00000467805|uniprotkb:B4DMC0|uniprotkb:K7EJ81	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:u5s1_human(display_long)|uniprotkb:EFTUD2(gene name)|psi-mi:EFTUD2(display_short)|uniprotkb:KIAA0031(gene name synonym)|uniprotkb:SNRP116(gene name synonym)|uniprotkb:U5 snRNP-specific protein, 116 kDa(gene name synonym)|uniprotkb:Elongation factor Tu GTP-binding domain-containing protein 2(gene name synonym)|uniprotkb:SNU114 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001136077.1|refseq:NP_004238.3|refseq:NP_001245282.1|go:"GO:0042220"(response to cocaine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR041095|interpro:IPR044121|mint:Q15029|rcsb pdb:3JCR|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|go:"GO:0035690"|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000108883(gene)|ensembl:ENST00000426333(transcript)|ensembl:ENST00000591382(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030623"(U5 snRNA binding)|refseq:NP_001245283.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:/dBQ7TFnGr31AYrb5e215eQ4vfc9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9H9A5	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1054261|uniprotkb:Q9BU30|uniprotkb:Q9H5J7|uniprotkb:Q9H8X1|uniprotkb:Q9H9W0|uniprotkb:Q9HAH3|uniprotkb:Q9UFJ2|uniprotkb:B7Z7L1|uniprotkb:F8WAF2|intact:EBI-2562025|ensembl:ENSP00000330060	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:cno10_human(display_long)|uniprotkb:CNOT10(gene name)|psi-mi:CNOT10(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001243670.1|refseq:NP_056257.1|refseq:NP_001243671.1|ensembl:ENSG00000182973(gene)|ensembl:ENST00000328834(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039740|mint:Q9H9A5|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-46839N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:92BjBXGyxALldfF9AVpP+EFN38k9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14920	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-81266|uniprotkb:O75327|uniprotkb:B4E0U4|uniprotkb:B4DZ30|ensembl:ENSP00000430684	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ikkb_human(display_long)|uniprotkb:IKBKB(gene name)|psi-mi:IKBKB(display_short)|uniprotkb:IKKB(gene name synonym)|uniprotkb:I-kappa-B kinase 2(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase beta(gene name synonym)|uniprotkb:Serine/threonine protein kinase IKBKB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001177649.1|refseq:NP_001547.1|interpro:IPR000626(Ubiquitin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR022007|interpro:IPR029071|interpro:IPR041185|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1990459"(transferrin receptor binding)|mint:O14920|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:4E3C|rcsb pdb:4KIK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209543|reactome:R-HSA-209560|ensembl:ENSG00000104365(gene)|ensembl:ENST00000520810(transcript)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|reactome:R-HSA-2871837|go:"GO:0019901"(protein kinase binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903140"(regulation of establishment of endothelial barrier)|refseq:NP_001229707.1|dip:DIP-27527N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:Za/bWjmPFaKOGVvQ00rtBfikvhI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q9Y263	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-1994037|uniprotkb:Q53EU5|uniprotkb:Q5VY33|uniprotkb:Q9NUL8|uniprotkb:Q9NVE9|uniprotkb:Q9UF53|uniprotkb:Q9Y5L1|ensembl:ENSP00000380460	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:plap_human(display_long)|uniprotkb:PLAA(gene name)|psi-mi:PLAA(display_short)|uniprotkb:PLAP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001026859.1|ensembl:ENSG00000137055(gene)|ensembl:ENST00000397292(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0016005"(phospholipase A2 activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1900045"(negative regulation of protein K63-linked ubiquitination)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013535(PUL)|interpro:IPR015155("PFU (PLAA family ubiquitin binding)")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036322|interpro:IPR038122|mint:Q9Y263|rcsb pdb:2K89|rcsb pdb:2K8A|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:3EBB	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:SoClA00UzZpX9vV1cJWvefY6eY89606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q14344	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-465387|ensembl:ENSP00000400717|uniprotkb:Q8TD70|uniprotkb:B7Z7R0|uniprotkb:F5H1G8|uniprotkb:B2R977	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:gna13_human(display_long)|uniprotkb:GNA13(gene name)|psi-mi:GNA13(display_short)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000120063(gene)|ensembl:ENST00000439174(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031752"(D5 dopamine receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-428930|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-456926|refseq:NP_006563.2|refseq:NP_001269354.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:ZYmlpIogjya3/ejteQS1YC+LqKI9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P05107	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-300173|ensembl:ENSP00000303242|ensembl:ENSP00000347279|ensembl:ENSP00000380948|ensembl:ENSP00000380950|ensembl:ENSP00000380955|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008305"(integrin complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034687"(integrin alphaL-beta2 complex)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0034689"(integrin alphaX-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043113"(receptor clustering)|ensembl:ENSG00000160255(gene)|ensembl:ENST00000302347(transcript)|ensembl:ENST00000355153(transcript)|ensembl:ENST00000397850(transcript)|ensembl:ENST00000397852(transcript)|ensembl:ENST00000397857(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:0043235"(receptor complex)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:1990266"(neutrophil migration)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|go:"GO:0046872"(metal ion binding)|interpro:IPR036465|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|mint:P05107|rcsb pdb:1JX3|rcsb pdb:1L3Y|rcsb pdb:1YUK|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:2JF1|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|go:"GO:0070821"(tertiary granule membrane)|rcsb pdb:4NEH|rcsb pdb:4NEN|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:aaycm8Q/rmu01cs20dw399oJjFE9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P36222	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6917454|ensembl:ENSP00000255409|uniprotkb:B2R7B0|uniprotkb:P30923|uniprotkb:Q8IVA4|uniprotkb:Q96HI7	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:ch3l1_human(display_long)|uniprotkb:CHI3L1(gene name)|psi-mi:CHI3L1(display_short)|uniprotkb:39 kDa synovial protein(gene name synonym)|uniprotkb:Cartilage glycoprotein 39(gene name synonym)|uniprotkb:YKL-40(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000133048(gene)|ensembl:ENST00000255409(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006032"(chitin catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008061"(chitin binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030324"(lung development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051216"(cartilage development)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070741"(response to interleukin-6)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR001223(Glycoside hydrolase, family 18, catalytic domain)|interpro:IPR011583(Chitinase II)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028538|interpro:IPR029070|rcsb pdb:1HJV|rcsb pdb:1HJW|rcsb pdb:1HJX|rcsb pdb:1LA7|rcsb pdb:1NWR|rcsb pdb:1NWS|rcsb pdb:1NWT|reactome:R-HSA-6798695|rcsb pdb:1NWU|refseq:NP_001267.2	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:zZfR9p8Rzm74r9jur2r1nUoBR4M9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q16720	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6917449|uniprotkb:B7WNR8|uniprotkb:B7WNY5|uniprotkb:Q12995|uniprotkb:Q16858|intact:EBI-7695893|intact:MINT-2807671|ensembl:ENSP00000263519|ensembl:ENSP00000343886	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:at2b3_human(display_long)|uniprotkb:ATP2B3(gene name)|psi-mi:ATP2B3(display_short)|uniprotkb:Plasma membrane calcium ATPase isoform 3(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001001344.1|refseq:NP_068768.2|refseq:XP_005274747.1|refseq:XP_005274748.1|refseq:XP_005274749.1|ensembl:ENSG00000067842(gene)|ensembl:ENST00000263519(transcript)|ensembl:ENST00000349466(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990032"(parallel fiber)|go:"GO:1990034"(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q16720|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:IvqyUoRi6v8R4/VIpuiEuRhCw949606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:Q13509	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-350989|uniprotkb:Q9BTZ0|uniprotkb:Q9BW10|ensembl:ENSP00000320295|uniprotkb:A8K854	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tbb3_human(display_long)|uniprotkb:TUBB3(gene name)|psi-mi:TUBB3(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:Tubulin beta-III(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001184110.1|refseq:NP_006077.2|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-6807878|ensembl:ENSG00000258947(gene)|ensembl:ENST00000315491(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13509|rcsb pdb:5IJ9|rcsb pdb:5JCO|rcsb pdb:6E7B|rcsb pdb:6S8L|rcsb pdb:6WSL|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|rcsb pdb:5IJ0|dip:DIP-31505N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:A69G+idFQmuzkmCsGyBtGVqglSo9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P04350	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355007|uniprotkb:B3KQP4|uniprotkb:Q969E5|ensembl:ENSP00000264071	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:tbb4a_human(display_long)|uniprotkb:TUBB4A(gene name)|psi-mi:TUBB4A(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:Tubulin 5 beta(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006078.2|ensembl:ENSG00000104833(gene)|ensembl:ENST00000264071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0033269"(internode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P04350|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001276052.1|refseq:NP_001276056.1|refseq:NP_001276058.1|refseq:NP_001276059.1|refseq:NP_001276060.1	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:mMveBNZkQs2x0dyHm/ghVWBe4/49606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:P13716	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6917458|uniprotkb:A8K375|uniprotkb:B2R6F2|uniprotkb:Q16870|uniprotkb:Q16871|uniprotkb:Q9BVQ9|ensembl:ENSP00000386284	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:hem2_human(display_long)|uniprotkb:ALAD(gene name)|psi-mi:ALAD(display_short)|uniprotkb:Porphobilinogen synthase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917061|imex:IM-21247-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001003945.1|refseq:XP_011516666.1|refseq:NP_000022.3|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046689"(response to mercury ion)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051597"(response to methylmercury)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070541"(response to platinum ion)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071284"(cellular response to lead ion)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904854"(proteasome core complex binding)|interpro:IPR001731(Tetrapyrrole biosynthesis, porphobilinogen synthase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR030656|rcsb pdb:1E51|rcsb pdb:1PV8|rcsb pdb:5HMS|rcsb pdb:5HNR|reactome:R-HSA-189451|reactome:R-HSA-6798695|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000148218(gene)|ensembl:ENST00000409155(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003824"(catalytic activity)|go:"GO:0004655"(porphobilinogen synthase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009635"(response to herbicide)|go:"GO:0010039"(response to iron ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010266"(response to vitamin B1)|go:"GO:0010269"(response to selenium ion)|go:"GO:0014823"(response to activity)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043200"(response to amino acid)	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:1, suppl. table 1|comment:"The identity of 14 interacting partners (IMB1, XPO2, IPO7, PSMD2, PSD12, PSD11, XPO1, PSD7, PSMD6, PSMD3, PSD13, PSDE, XPO7, PSMD1) was verified by additional immunoaffinity and western blot."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2020/12/11	-	rogid:2545gfRH9UwPlIt863Ul/qY/2pY9606	intact-crc:63021C98B98AF968	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
chebi:"CHEBI:34159"	uniprotkb:O14980	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917616|imex:IM-21247-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:S1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/05	2014/10/16	-	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	intact-crc:D51EC58D1A0F367F	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:34159"	chebi:"CHEBI:34159"	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-6915594|chebi:"CHEBI:616370"	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917653|imex:IM-21247-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	figure legend:S1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/05	2014/10/16	-	-	intact-crc:2076DF0729FFA1B5	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:34159"	uniprotkb:O14980	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917653|imex:IM-21247-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:S1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/08/05	2014/10/16	-	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	intact-crc:2076DF0729FFA1B5	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:34159"	uniprotkb:O14980	intact:EBI-6915594|chebi:"CHEBI:616370"	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:"15-deoxy-delta(12,14"(display_short)|psi-mi:"CHEBI:34159"(display_long)|intact:15-Deoxy-delta-12,14-PGJ2(synonym)|intact:15-Deoxy-delta-12,14-prostaglandin J2(synonym)|intact:15-Deoxy-PGJ2(synonym)|intact:"(5Z,12E,14Z)-11-hydroxyprosta-5,9,12,14-tetraen-1-oic acid"(iupac name)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Marcone et al. (2013)	pubmed:23606334|imex:IM-21247	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6917713|imex:IM-21247-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	-	inchi key:VHRUMKCAEVRUBK-WKELIDJCSA-N	-	figure legend:S1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-endothelium)|taxid:9606(Homo sapiens endothelail cells/endothelium)	-	2013/08/05	2014/10/16	-	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	intact-crc:C5BF326CC744F9A9	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)