#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O43924	uniprotkb:Q92834	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860493|rcsb pdb:4JHP|imex:IM-20908-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1	-	-	-	figure legend:Fig. 2c, Fig. 2d, Fig. 2f, Suppl. table 1|3d-resolution:1.90A|3d-r-factors:working 19.9%, free 22.1%|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606	intact-crc:A4656AB53F3974C6|rigid:FP1LJfc+evIJHBp5pg/CkAGzsyQ	false	-	sufficient binding region:7-368(IPR000408)	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43924	uniprotkb:Q92834	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860514|imex:IM-20908-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1	-	-	-	figure legend:Fig. 2f, Fig. 3b, Suppl. Fig. 3b, Suppl. Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606	intact-crc:1E7F5E6614F359DF|rigid:FP1LJfc+evIJHBp5pg/CkAGzsyQ	false	glutathione s tranferase tag:?-?|mutation disrupting interaction:48-48	sufficient binding region:1-392(IPR000408)|mutation disrupting interaction:216-216	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q15382-PRO_0000082708	uniprotkb:O43924	intact:EBI-6860739	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	psi-mi:q15382-pro_0000082708(display_long)|uniprotkb:RHEB(gene name)|psi-mi:RHEB(display_short)|uniprotkb:RHEB2(gene name synonym)|uniprotkb:Ras homolog enriched in brain(gene name synonym)	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860733|imex:IM-20908-3|rcsb pdb:3T5G	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055287(chain-parent)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	-	chain-seq-start:1|chain-seq-end:181	-	figure legend:Fig 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:Z54T37or+ZuVKOWDKC5VrePHbik9606	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	intact-crc:F12AF49BA6F7282F|rigid:5JhnLDtVuhjnv0wa050LxR7KWBg	false	S-farnesyl-L-cysteine methyl ester:181-181	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:O43924	uniprotkb:Q92834	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860752|imex:IM-20908-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1	-	-	-	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606	intact-crc:B2098C433C7196FC|rigid:bHY0EBCQoyEjmoPHMF+E5XStvrc	false	glutathione s tranferase tag:?-?	sufficient binding region:1-392(IPR000408)	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:O43924	uniprotkb:Q15382-PRO_0000082708	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-6860739	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:q15382-pro_0000082708(display_long)|uniprotkb:RHEB(gene name)|psi-mi:RHEB(display_short)|uniprotkb:RHEB2(gene name synonym)|uniprotkb:Ras homolog enriched in brain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860752|imex:IM-20908-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	intact:EBI-1055287(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:181	figure legend:Fig. 3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:Z54T37or+ZuVKOWDKC5VrePHbik9606	intact-crc:B2098C433C7196FC|rigid:bHY0EBCQoyEjmoPHMF+E5XStvrc	false	glutathione s tranferase tag:?-?	S-farnesyl-L-cysteine methyl ester:181-181	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q9WUL7	uniprotkb:O43924	intact:EBI-6860857|ensembl:ENSMUSP00000026009	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	psi-mi:arl3_mouse(display_long)|uniprotkb:Arl3(gene name)|psi-mi:Arl3(display_short)	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860925|imex:IM-20908-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:Q9WUL7|rcsb pdb:1FZQ|rcsb pdb:3BH6|rcsb pdb:3BH7|rcsb pdb:4GOJ|rcsb pdb:4ZI2|rcsb pdb:4ZI3|rcsb pdb:7OK7|reactome:R-MMU-5624138|ensembl:ENSMUSG00000025035(gene)|ensembl:ENSMUST00000026009(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|refseq:NP_062692.1|dip:DIP-29025N	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	-	-	-	figure legend:Suppl. Fig. 6c|comment:The authors claim that a ternary Pde6d-RPGR-Arl3 complex could not be identified in pull down experiments using His-tagged Arl3 as bait with RPGR and wild type Pde6d as prey.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:Pv4G4Y6wahs2lvrFtlxPhmF23ew10090	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	intact-crc:4D2E3834BE4FFFF9|rigid:g5UKzltxQNxWibfyVsmzyKXDGOQ	false	his tag:c-c	mutation:94-94,98-98	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q9WUL7	uniprotkb:Q92834	intact:EBI-6860857|ensembl:ENSMUSP00000026009	intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503	psi-mi:arl3_mouse(display_long)|uniprotkb:Arl3(gene name)|psi-mi:Arl3(display_short)	psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860925|imex:IM-20908-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:Q9WUL7|rcsb pdb:1FZQ|rcsb pdb:3BH6|rcsb pdb:3BH7|rcsb pdb:4GOJ|rcsb pdb:4ZI2|rcsb pdb:4ZI3|rcsb pdb:7OK7|reactome:R-MMU-5624138|ensembl:ENSMUSG00000025035(gene)|ensembl:ENSMUST00000026009(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|refseq:NP_062692.1|dip:DIP-29025N	refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1	-	-	-	figure legend:Suppl. Fig. 6c|comment:The authors claim that a ternary Pde6d-RPGR-Arl3 complex could not be identified in pull down experiments using His-tagged Arl3 as bait with RPGR and wild type Pde6d as prey.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:Pv4G4Y6wahs2lvrFtlxPhmF23ew10090	rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606	intact-crc:4D2E3834BE4FFFF9|rigid:g5UKzltxQNxWibfyVsmzyKXDGOQ	false	his tag:c-c	sufficient binding region:1-392(IPR000408)	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:O43924	uniprotkb:Q9D0J4	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-1033319|uniprotkb:Q9WUM1|ensembl:ENSMUSP00000025893	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:arl2_mouse(display_long)|uniprotkb:Arl2(gene name)|psi-mi:Arl2(display_short)	psi-mi:"MI:0096"(pull down)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6861459|imex:IM-20908-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	refseq:NP_062696.2|ensembl:ENSMUSG00000024944(gene)|ensembl:ENSMUST00000025893(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:4GOK|reactome:R-MMU-83936|reactome:R-MMU-9648002|dip:DIP-36659N	-	-	-	figure legend:Suppl. Fig. 6a|comment:Arl2 is bound to non-hydrolysable GTP analogue GppNHp.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:zb6s8gL3Fr5kyys6iB/rrgsj7qI10090	intact-crc:D8415060EF77F542|rigid:/esqfiF18/LIjEsHL8RUYPEmuyQ	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:O43924	uniprotkb:Q92834	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6861459|imex:IM-20908-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1	-	-	-	figure legend:Suppl. Fig. 6a|comment:Arl2 is bound to non-hydrolysable GTP analogue GppNHp.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606	intact-crc:D8415060EF77F542|rigid:/esqfiF18/LIjEsHL8RUYPEmuyQ	false	glutathione s tranferase tag:?-?	sufficient binding region:1-392(IPR000408)	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:O43924	uniprotkb:Q9WUL7	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-6860857|ensembl:ENSMUSP00000026009	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:arl3_mouse(display_long)|uniprotkb:Arl3(gene name)|psi-mi:Arl3(display_short)	psi-mi:"MI:0096"(pull down)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6861470|imex:IM-20908-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:Q9WUL7|rcsb pdb:1FZQ|rcsb pdb:3BH6|rcsb pdb:3BH7|rcsb pdb:4GOJ|rcsb pdb:4ZI2|rcsb pdb:4ZI3|rcsb pdb:7OK7|reactome:R-MMU-5624138|ensembl:ENSMUSG00000025035(gene)|ensembl:ENSMUST00000026009(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|refseq:NP_062692.1|dip:DIP-29025N	-	-	-	figure legend:Suppl. Fig. 6b|comment:Arl3 is bound to non-hydrolysable GTP analogue GppNHp.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:Pv4G4Y6wahs2lvrFtlxPhmF23ew10090	intact-crc:4C2011964FEE15B9|rigid:g5UKzltxQNxWibfyVsmzyKXDGOQ	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:O43924	uniprotkb:Q92834	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6861470|imex:IM-20908-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1	-	-	-	figure legend:Suppl. Fig. 6b|comment:Arl3 is bound to non-hydrolysable GTP analogue GppNHp.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606	intact-crc:4C2011964FEE15B9|rigid:g5UKzltxQNxWibfyVsmzyKXDGOQ	false	glutathione s tranferase tag:?-?	sufficient binding region:1-392(IPR000408)	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:O43924	uniprotkb:Q92834	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860805|imex:IM-20908-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1	-	-	-	figure legend:Fig. 3c, Suppl. Fig. 3a|kinetic_conditions:Temp = 20C; pH = 7.5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:500.0x10^-9(molar)	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606	intact-crc:18CDDB15CDE7939C|rigid:FP1LJfc+evIJHBp5pg/CkAGzsyQ	false	cy5 label:?-?	sufficient binding region:1-392(IPR000408)	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O43924	uniprotkb:Q15382-PRO_0000082708	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-6860739	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:q15382-pro_0000082708(display_long)|uniprotkb:RHEB(gene name)|psi-mi:RHEB(display_short)|uniprotkb:RHEB2(gene name synonym)|uniprotkb:Ras homolog enriched in brain(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860828|imex:IM-20908-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	intact:EBI-1055287(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:181	figure legend:Fig. 3c|kinetic_conditions:Temp = 20C; pH = 7.5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:Z54T37or+ZuVKOWDKC5VrePHbik9606	intact-crc:F637B3FC1E3A04C9|rigid:bHY0EBCQoyEjmoPHMF+E5XStvrc	false	cy5 label:?-?	S-farnesyl-L-cysteine methyl ester:181-181|sufficient binding region:174-181	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O43924	uniprotkb:Q92834	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860828|imex:IM-20908-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1	-	-	-	figure legend:Fig. 3c|kinetic_conditions:Temp = 20C; pH = 7.5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606	intact-crc:F637B3FC1E3A04C9|rigid:bHY0EBCQoyEjmoPHMF+E5XStvrc	false	cy5 label:?-?	sufficient binding region:1-392(IPR000408)	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q15382-PRO_0000082708	uniprotkb:O43924	intact:EBI-6860739	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	psi-mi:q15382-pro_0000082708(display_long)|uniprotkb:RHEB(gene name)|psi-mi:RHEB(display_short)|uniprotkb:RHEB2(gene name synonym)|uniprotkb:Ras homolog enriched in brain(gene name synonym)	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6861384|rcsb pdb:3T5G|imex:IM-20908-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1055287(chain-parent)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	-	chain-seq-start:1|chain-seq-end:181	-	figure legend:Fig. 4b, Suppl. Fig. 5|kinetic_conditions:Temp = 20C; pH = 7.5|comment:The presence of RPGR had no effect on the association or dissociation rate constants of the Rheb-Pde6d interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kon:2.0(second -1)|koff:2.0(second -1)	2013/06/13	2014/10/16	rogid:Z54T37or+ZuVKOWDKC5VrePHbik9606	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	intact-crc:AB40013EF5F8484B|rigid:5JhnLDtVuhjnv0wa050LxR7KWBg	false	fluorescein label:174-174|S-farnesyl-L-cysteine methyl ester:181-181|mutation:174-174|sufficient binding region:174-181	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O43924	uniprotkb:Q15382-PRO_0000082708	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-6860739	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:q15382-pro_0000082708(display_long)|uniprotkb:RHEB(gene name)|psi-mi:RHEB(display_short)|uniprotkb:RHEB2(gene name synonym)|uniprotkb:Ras homolog enriched in brain(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6861442|imex:IM-20908-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	intact:EBI-1055287(chain-parent)	-	-	chain-seq-start:1|chain-seq-end:181	figure legend:Fig 4b|kinetic_conditions:Temp = 20C; pH = 7.5|comment:Addition of non-hydrolysable GTP analogue GppNHp-bound Arl3 resulted in dissociation of the complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:Z54T37or+ZuVKOWDKC5VrePHbik9606	intact-crc:48D8D826568F253B|rigid:bHY0EBCQoyEjmoPHMF+E5XStvrc	false	-	S-farnesyl-L-cysteine methyl ester:181-181|fluorescein label:174-174|mutation:174-174|sufficient binding region:174-181	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O43924	uniprotkb:Q92834	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6861442|imex:IM-20908-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1	-	-	-	figure legend:Fig 4b|kinetic_conditions:Temp = 20C; pH = 7.5|comment:Addition of non-hydrolysable GTP analogue GppNHp-bound Arl3 resulted in dissociation of the complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606	intact-crc:48D8D826568F253B|rigid:bHY0EBCQoyEjmoPHMF+E5XStvrc	false	-	sufficient binding region:1-392(IPR000408)	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9WUL7	uniprotkb:O43924	intact:EBI-6860857|ensembl:ENSMUSP00000026009	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	psi-mi:arl3_mouse(display_long)|uniprotkb:Arl3(gene name)|psi-mi:Arl3(display_short)	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860855|imex:IM-20908-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:Q9WUL7|rcsb pdb:1FZQ|rcsb pdb:3BH6|rcsb pdb:3BH7|rcsb pdb:4GOJ|rcsb pdb:4ZI2|rcsb pdb:4ZI3|rcsb pdb:7OK7|reactome:R-MMU-5624138|ensembl:ENSMUSG00000025035(gene)|ensembl:ENSMUST00000026009(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|refseq:NP_062692.1|dip:DIP-29025N	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	-	-	-	figure legend:Fig. 3e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:Pv4G4Y6wahs2lvrFtlxPhmF23ew10090	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	intact-crc:67C6CC4CB05696A5|rigid:g5UKzltxQNxWibfyVsmzyKXDGOQ	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q9WUL7	uniprotkb:Q92834	intact:EBI-6860857|ensembl:ENSMUSP00000026009	intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503	psi-mi:arl3_mouse(display_long)|uniprotkb:Arl3(gene name)|psi-mi:Arl3(display_short)	psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860855|imex:IM-20908-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:Q9WUL7|rcsb pdb:1FZQ|rcsb pdb:3BH6|rcsb pdb:3BH7|rcsb pdb:4GOJ|rcsb pdb:4ZI2|rcsb pdb:4ZI3|rcsb pdb:7OK7|reactome:R-MMU-5624138|ensembl:ENSMUSG00000025035(gene)|ensembl:ENSMUST00000026009(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|refseq:NP_062692.1|dip:DIP-29025N	refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1	-	-	-	figure legend:Fig. 3e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:Pv4G4Y6wahs2lvrFtlxPhmF23ew10090	rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606	intact-crc:67C6CC4CB05696A5|rigid:g5UKzltxQNxWibfyVsmzyKXDGOQ	false	-	sufficient binding region:1-392(IPR000408)	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q92834	uniprotkb:O43924	intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym)	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860902|imex:IM-20908-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	-	-	-	figure legend:Fig. 3f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	intact-crc:FA4F44A6DAFB6992|rigid:FP1LJfc+evIJHBp5pg/CkAGzsyQ	false	sufficient binding region:1-392(IPR000408)	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:O43924	uniprotkb:Q9D0J4	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	intact:EBI-1033319|uniprotkb:Q9WUM1|ensembl:ENSMUSP00000025893	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:arl2_mouse(display_long)|uniprotkb:Arl2(gene name)|psi-mi:Arl2(display_short)	psi-mi:"MI:0071"(molecular sieving)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860909|imex:IM-20908-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	refseq:NP_062696.2|ensembl:ENSMUSG00000024944(gene)|ensembl:ENSMUST00000025893(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:4GOK|reactome:R-MMU-83936|reactome:R-MMU-9648002|dip:DIP-36659N	-	-	-	figure legend:Fig. 3f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	rogid:zb6s8gL3Fr5kyys6iB/rrgsj7qI10090	intact-crc:EDC566D325E0287A|rigid:8IB9ZXjbTXtrmErMVoLM+DnbIVo	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q9D0J4	uniprotkb:O43924	intact:EBI-1033319|uniprotkb:Q9WUM1|ensembl:ENSMUSP00000025893	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	psi-mi:arl2_mouse(display_long)|uniprotkb:Arl2(gene name)|psi-mi:Arl2(display_short)	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860913|imex:IM-20908-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062696.2|ensembl:ENSMUSG00000024944(gene)|ensembl:ENSMUST00000025893(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:4GOK|reactome:R-MMU-83936|reactome:R-MMU-9648002|dip:DIP-36659N	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	-	-	-	figure legend:Fig. 3g|comment:The phe94ala-ile98ala Pde6d mutant forms a stable ternary complex with RPGR and Arl2, while for wild type Pde6d only the binary Pde6d-RPGR and Pde6d-Arl2 complexes were observed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:zb6s8gL3Fr5kyys6iB/rrgsj7qI10090	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	intact-crc:1E0EACF0815F12EB|rigid:/esqfiF18/LIjEsHL8RUYPEmuyQ	false	-	mutation:94-94,98-98	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q9D0J4	uniprotkb:Q92834	intact:EBI-1033319|uniprotkb:Q9WUM1|ensembl:ENSMUSP00000025893	intact:EBI-6558417|ensembl:ENSP00000343671|uniprotkb:B1ARN3|uniprotkb:E9PE28|uniprotkb:O00702|uniprotkb:O00737|uniprotkb:Q3KN84|uniprotkb:Q8N5T6|uniprotkb:Q93039|uniprotkb:Q9HD29|uniprotkb:Q9UMR1|intact:EBI-12703128|intact:EBI-16431503	psi-mi:arl2_mouse(display_long)|uniprotkb:Arl2(gene name)|psi-mi:Arl2(display_short)	psi-mi:rpgr_human(display_long)|uniprotkb:RPGR(gene name)|psi-mi:RPGR(display_short)|uniprotkb:RP3(gene name synonym)|uniprotkb:XLRP3(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6860913|imex:IM-20908-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062696.2|ensembl:ENSMUSG00000024944(gene)|ensembl:ENSMUST00000025893(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:4GOK|reactome:R-MMU-83936|reactome:R-MMU-9648002|dip:DIP-36659N	refseq:XP_016885199.1|ensembl:ENSG00000156313(gene)|ensembl:ENST00000339363(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007601"(visual perception)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042073"(intraciliary transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060271"(cilium assembly)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|rcsb pdb:4JHN|rcsb pdb:4JHP|rcsb pdb:4QAM|refseq:NP_000319.1|refseq:NP_001030025.1	-	-	-	figure legend:Fig. 3g|comment:The phe94ala-ile98ala Pde6d mutant forms a stable ternary complex with RPGR and Arl2, while for wild type Pde6d only the binary Pde6d-RPGR and Pde6d-Arl2 complexes were observed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:zb6s8gL3Fr5kyys6iB/rrgsj7qI10090	rogid:yG3e/pDbkwML2e7J8BMMXY/EVPM9606	intact-crc:1E0EACF0815F12EB|rigid:/esqfiF18/LIjEsHL8RUYPEmuyQ	false	-	sufficient binding region:1-392(IPR000408)	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:Q9WUL7	uniprotkb:O43924	intact:EBI-6860857|ensembl:ENSMUSP00000026009	intact:EBI-712685|uniprotkb:O43250|ensembl:ENSP00000287600	psi-mi:arl3_mouse(display_long)|uniprotkb:Arl3(gene name)|psi-mi:Arl3(display_short)	psi-mi:pde6d_human(display_long)|uniprotkb:Protein p17(gene name synonym)|uniprotkb:PDE6D(gene name)|psi-mi:PDE6D(display_short)|uniprotkb:PDED(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Wätzlich et al. (2013)	pubmed:23559067|imex:IM-20908	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6869600|imex:IM-20908-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:Q9WUL7|rcsb pdb:1FZQ|rcsb pdb:3BH6|rcsb pdb:3BH7|rcsb pdb:4GOJ|rcsb pdb:4ZI2|rcsb pdb:4ZI3|rcsb pdb:7OK7|reactome:R-MMU-5624138|ensembl:ENSMUSG00000025035(gene)|ensembl:ENSMUST00000026009(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|refseq:NP_062692.1|dip:DIP-29025N	refseq:NP_001277947.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050896"(response to stimulus)|interpro:IPR008015(GMP phosphodiesterase, delta subunit)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017287(Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit)|interpro:IPR037036|mint:O43924|rcsb pdb:1KSG|rcsb pdb:1KSH|rcsb pdb:1KSJ|rcsb pdb:3T5G|rcsb pdb:3T5I|rcsb pdb:4JHP|rcsb pdb:4JV6|rcsb pdb:4JV8|rcsb pdb:4JVB|rcsb pdb:4JVF|rcsb pdb:5E80|rcsb pdb:5E8F|rcsb pdb:5F2U|rcsb pdb:5ML2|rcsb pdb:5ML3|rcsb pdb:5ML4|rcsb pdb:5ML6|rcsb pdb:5ML8|rcsb pdb:5NAL|rcsb pdb:5TAR|rcsb pdb:5TB5|rcsb pdb:5X72|rcsb pdb:5X73|rcsb pdb:5X74|rcsb pdb:5YAV|rcsb pdb:5YAW|reactome:R-HSA-5624958|ensembl:ENSG00000156973(gene)|ensembl:ENST00000287600(transcript)|go:"GO:0005095"(GTPase inhibitor activity)|reactome:R-HSA-9648002|refseq:NP_002592.1|dip:DIP-36660N	-	-	-	figure legend:Fig. 3e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/13	2014/10/16	rogid:Pv4G4Y6wahs2lvrFtlxPhmF23ew10090	rogid:dfEOckvNZPhkWSeQnKr4ugEdEmM9606	intact-crc:77343052B3F92F12|rigid:yA6MPYQvzfLEz+ZXGa95GTwfltA	false	-	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)