#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A5A8Q6 uniprotkb:Q17865 intact:EBI-6530664|ensemblmetazoa:F57C9.4c.1 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:a5a8q6_caeel(display_long)|uniprotkb:CELE_F57C9.4(orf name)|uniprotkb:F57C9.4(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530666|imex:IM-18681-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F57C9.4c.1(transcript)|ensemblmetazoa:WBGene00019011(gene)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001122489.1|wormbase:F57C9.4c|interpro:IPR036236|uniprotkb:A5A8Q6(identity)|wormbase:WBGene00019011(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:gweOlBfcxlVKCgsQwAeX60L9hGY6239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:8812459FF281F61D|rigid:S5Wd+YQ9vID0M3tFZ4JycLGiM3g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 uniprotkb:C7IVR4-3 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 intact:EBI-10943090|ensemblmetazoa:F53A3.4c.1 psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:c7ivr4-3(display_long)|uniprotkb:pqn-41(gene name)|psi-mi:pqn-41(display_short)|uniprotkb:"Prion-like-(Q/N-rich)-domain-bearing protein 41"(gene name synonym)|uniprotkb:F53A3.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530634|imex:IM-18681-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) ensemblmetazoa:F53A3.4c.1(transcript)|ensemblmetazoa:WBGene00004128(gene)|intact:EBI-6530632(isoform-parent)|uniprotkb:C7IVR6(identity)|wormbase:WBGene00018722(identity) - - isoform-comment:No experimental confirmation available. figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/07/27 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:46eoZcoTJaSfxYjTrDrL3AcFGus6239 intact-crc:C25CBD27D6FD5DD3|rigid:Z045Uj9MB1q7rx91vMZkVWORwUg false sufficient binding region:430-486 sufficient binding region:1186-1478 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17865 uniprotkb:Q17865 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530651|imex:IM-18681-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:1727D74D22C331AF|rigid:mLQjBMX9gRHiT0/nCsuPGQi2UsU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39055 uniprotkb:P55853 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530705|imex:IM-18681-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933|uniprotkb:P55853(identity)|wormbase:WBGene00004888(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 intact-crc:8852C5FC0E2CA63A|rigid:wSqZRszgDgGzw+8yKjx9MPOkifA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39055 uniprotkb:Q9N2Z7 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 intact:EBI-317369|uniprotkb:Q95XU3|uniprotkb:V6CJJ8|uniprotkb:V6CLY4|ensemblmetazoa:Y65B4BR.4a.1 psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:wwp1_caeel(display_long)|uniprotkb:wwp-1(gene name)|psi-mi:wwp-1(display_short)|uniprotkb:Y65B4BR.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530733|imex:IM-18681-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) wormbase:Y65B4BR.4b|wormbase:Y65B4BR.4c|wormbase:Y65B4BR.4d|refseq:NP_740775.1|wormbase:Y65B4BR.4a|ensemblmetazoa:WBGene00007009(gene)|ensemblmetazoa:Y65B4BR.4a.1(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|reactome:R-CEL-1253288|reactome:R-CEL-983168|reactome:R-CEL-9013406|reactome:R-CEL-9013420|refseq:NP_001293271.1|refseq:NP_001293272.1|refseq:NP_740776.1|dip:DIP-25758N|reactome:R-CEL-2672351|reactome:R-CEL-8948751|reactome:R-CEL-5610780|reactome:R-CEL-5632684|uniprotkb:Q95XU3(identity)|wormbase:WBGene00007009(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2021/06/18 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 rogid:PlZNO3kcb422riUzp2aLH7Xaz3E6239 intact-crc:4731935ED4F41B58|rigid:wRC9SajUL6FTJordhQ/rR5Nw7T4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62203 uniprotkb:G5ED33 intact:EBI-320780|ensemblmetazoa:F32B4.4a.1|intact:EBI-6530763|uniprotkb:F5GUF6|uniprotkb:Q7Z0X2 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:phm2_caeel(display_long)|uniprotkb:phm-2(gene name)|psi-mi:phm-2(display_short)|uniprotkb:F32B4.4(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530759|imex:IM-18681-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F32B4.4a|ensemblmetazoa:F32B4.4a.1(transcript)|ensemblmetazoa:WBGene00009314(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007586"(digestion)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036361|refseq:NP_001021441.1|refseq:NP_001251667.1|refseq:NP_001021440.2|dip:DIP-25849N|reactome:R-CEL-3899300|wormbase:F32B4.4b|wormbase:F32B4.4c|uniprotkb:F5GUF6(identity)|wormbase:WBGene00009314(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/03/02 rogid:69Kg/RUbe1gThWpe8yrWyt9o0bQ6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:6EFB6EFB296DD39D|rigid:A4z/M6Gby3cZiWqv/Fgsen7CRAs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:Q8MNT0 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-324442|ensemblmetazoa:F28F5.3c.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:q8mnt0_caeel(display_long)|uniprotkb:lim-8(gene name)|psi-mi:lim-8(display_short)|uniprotkb:F28F5.3(orf name)|uniprotkb:CELE_F28F5.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530746|imex:IM-18681-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_741201.1|wormbase:F28F5.3c|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|ensemblmetazoa:F28F5.3c.1(transcript)|ensemblmetazoa:WBGene00017904(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031430"(M band)|go:"GO:0032034"(myosin II head/neck binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|interpro:IPR036034|interpro:IPR041489|interpro:IPR029980|uniprotkb:Q8MNT0(identity)|wormbase:WBGene00017904(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:Prm6YPAZkkBApz/l8EwwI2JDZvk6239 intact-crc:F6298052E54236FB|rigid:mw/bj/IDUU0mdgORx3BavD6Ph2Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39055 uniprotkb:P39055 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530692|imex:IM-18681-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:ACA48FD40CBE3C73|rigid:OrISFsB5oxnVW9Tkc8cDWdIwY7M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17865 uniprotkb:G5EGG0 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 intact:EBI-311986|ensemblmetazoa:K09B11.9a.1 psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:g5egg0_caeel(display_long)|uniprotkb:uso-1(gene name)|psi-mi:uso-1(display_short)|uniprotkb:K09B11.9(orf name)|uniprotkb:CELE_K09B11.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530679|imex:IM-18681-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) uniprotkb:Q9XU77(uniprot-removed-ac)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR011989(Armadillo-like helical)|reactome:R-CEL-6807878|ensemblmetazoa:K09B11.9a.1(transcript)|ensemblmetazoa:WBGene00010713(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0061025"(membrane fusion)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001040973.1|wormbase:K09B11.9a|interpro:IPR041209|reactome:R-CEL-204005|uniprotkb:G5EGG0(identity)|wormbase:WBGene00010713(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 rogid:zWbAI5mawzzlFIZP4rcR6seLYn86239 intact-crc:5FBBC973720BD5F9|rigid:m0xUoJi8PgNp0tXrL2o+Yqmte2k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39055 uniprotkb:G8JYB2 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 intact:EBI-6530722|ensemblmetazoa:Y23H5A.5d.1 psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:g8jyb2_caeel(display_long)|uniprotkb:Y23H5A.5(orf name)|uniprotkb:ctn-1(gene name)|psi-mi:ctn-1(display_short)|uniprotkb:CELE_Y23H5A.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530718|imex:IM-18681-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) interpro:IPR030045|ensemblmetazoa:WBGene00000832(gene)|ensemblmetazoa:Y23H5A.5d.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|refseq:NP_740813.2|wormbase:Y23H5A.5d|interpro:IPR036723|uniprotkb:G8JYB2(identity)|wormbase:WBGene00000832(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 rogid:Vi3tH7mbD/nDGfvpd5acMGXv7Qw6239 intact-crc:5B0A7A636F32D7B8|rigid:JiBwNbQH2qcg7RyWj8SFScHNI4Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ13 uniprotkb:G5ED33 intact:EBI-6530841|ensemblmetazoa:F59F3.6.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:q8mq13_caeel(display_long)|uniprotkb:CELE_F59F3.6(orf name)|uniprotkb:F59F3.6(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530843|imex:IM-18681-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F59F3.6.1(transcript)|ensemblmetazoa:WBGene00010335(gene)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_741899.1|wormbase:F59F3.6|uniprotkb:Q8MQ13(identity)|wormbase:WBGene00010335(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:cWBLR2mBejFpPZRal6w69itlyRw6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:71687A1A1283B026|rigid:K79GduiN8nCJ5lIDTE0kqTbiqWA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XUW7 uniprotkb:G5ED33 intact:EBI-2416134|ensemblmetazoa:F58E10.5.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:q9xuw7_caeel(display_long)|uniprotkb:end-3(gene name)|psi-mi:end-3(display_short)|uniprotkb:CELE_F58E10.5(orf name)|uniprotkb:F58E10.5(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530828|imex:IM-18681-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506480.1|wormbase:F58E10.5|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|reactome:R-CEL-9018519|interpro:IPR039355|ensemblmetazoa:F58E10.5.1(transcript)|ensemblmetazoa:WBGene00001311(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007369"(gastrulation)|go:"GO:0007501"(mesodermal cell fate specification)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045165"(cell fate commitment)|uniprotkb:Q9XUW7(identity)|wormbase:WBGene00001311(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:rZwScfOEvg1otEOcWVCCmp2fD/06239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:8E910CC86660C9D2|rigid:FUYgsFFhyh7qj9MfKCZMOqOp+Vk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:Q20759 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-312110|ensemblmetazoa:F54C9.11.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:q20759_caeel(display_long)|uniprotkb:F54C9.11(orf name)|uniprotkb:CELE_F54C9.11(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530800|imex:IM-18681-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_495817.3|ensemblmetazoa:F54C9.11.1(transcript)|ensemblmetazoa:WBGene00010045(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0006887"(exocytosis)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|interpro:IPR040351|wormbase:F54C9.11|reactome:R-CEL-5620912|reactome:R-CEL-5620916|reactome:R-CEL-5620922|dip:DIP-24444N|reactome:R-CEL-8876198|uniprotkb:Q20759(identity)|wormbase:WBGene00010045(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:sPGvGy3w4P+cRRYy3dUghqx/A8w6239 intact-crc:D0791DCD24825878|rigid:uTcSyIjVQolsE97mX3UubW8IvGA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:Q20712 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-325968|ensemblmetazoa:F53B3.3.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:q20712_caeel(display_long)|uniprotkb:F53B3.3(orf name)|uniprotkb:CELE_F53B3.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530787|imex:IM-18681-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_508497.3|wormbase:F53B3.3|ensemblmetazoa:F53B3.3.1(transcript)|ensemblmetazoa:WBGene00018742(gene)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|dip:DIP-25066N|uniprotkb:Q20712(identity)|wormbase:WBGene00018742(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:DVUtviRrC9eQgxhAF1NqxTYlHe86239 intact-crc:A4C5B3BBEB84C7BD|rigid:cAXAC94eU8pwESIy4uoPWC5tyJw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20476 uniprotkb:G5ED33 intact:EBI-320925|ensemblmetazoa:F46G10.1a.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:q20476_caeel(display_long)|uniprotkb:F46G10.1(orf name)|uniprotkb:CELE_F46G10.1(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530774|imex:IM-18681-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123145.1|wormbase:F46G10.1a|ensemblmetazoa:F46G10.1a.1(transcript)|ensemblmetazoa:WBGene00009796(gene)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|dip:DIP-26144N|uniprotkb:Q20476(identity)|wormbase:WBGene00009796(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:PrgXqEkZMuGaOENxnt+7wvX959k6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:F941B9F57918334F|rigid:AIH/oOqnqeQjYhCWj2HHmKWNFcM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:Q20769 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-6530817|ensemblmetazoa:F54D5.3.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:q20769_caeel(display_long)|uniprotkb:CELE_F54D5.3(orf name)|uniprotkb:F54D5.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530813|imex:IM-18681-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) ensemblmetazoa:F54D5.3.1(transcript)|ensemblmetazoa:WBGene00010049(gene)|refseq:NP_496473.1|wormbase:F54D5.3|interpro:IPR035274|uniprotkb:Q20769(identity)|wormbase:WBGene00010049(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:NuBoNA2X+HhejRoXTON2zN6RMno6239 intact-crc:6CF2DB2188E25194|rigid:TLdkklmaVKSE6iQ0eNG1llJ64jU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21882 uniprotkb:G5ED33 intact:EBI-311857|uniprotkb:Q1NZ16|ensemblmetazoa:R09H10.3a.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:hiuh1_caeel(display_long)|uniprotkb:R09H10.3(orf name)|uniprotkb:Transthyretin-like protein R09H10.3(gene name synonym) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530871|imex:IM-18681-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0033971"(hydroxyisourate hydrolase activity)|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:R09H10.3a.1(transcript)|ensemblmetazoa:WBGene00011181(gene)|refseq:NP_001040980.1|refseq:NP_001040981.1|wormbase:R09H10.3a|wormbase:R09H10.3b|interpro:IPR014306(Hydroxyisourate hydrolase)|interpro:IPR023418|interpro:IPR000895(Transthyretin)|interpro:IPR023416|interpro:IPR023419|reactome:R-CEL-6798695|interpro:IPR036817|reactome:R-CEL-975634|uniprotkb:Q21882(identity)|wormbase:WBGene00011181(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:u3JiggHOXSoy1ClJeGbiWPwZ2c46239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:DEEFEC0BD6B4753A|rigid:iED0E3mtKXOzruT2z4rral4sov4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:Q9NET8 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-314841|ensemblmetazoa:Y39B6A.11.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:q9net8_caeel(display_long)|uniprotkb:CELE_Y39B6A.11(orf name)|uniprotkb:dyf-17(gene name)|psi-mi:dyf-17(display_short)|uniprotkb:Y39B6A.11(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530966|imex:IM-18681-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_741687.1|wormbase:Y39B6A.11|ensemblmetazoa:WBGene00012673(gene)|ensemblmetazoa:Y39B6A.11.1(transcript)|go:"GO:0035869"(ciliary transition zone)|dip:DIP-24948N|uniprotkb:Q9NET8(identity)|wormbase:WBGene00012673(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:riiV5wEHQR3fxvWwwfMg31/zi+U6239 intact-crc:E94FB47544C68069|rigid:9W3U8kTAc88e0u9dNqta2DQvrj4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:O16638 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-6530951|ensemblmetazoa:W09G10.3.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:o16638_caeel(display_long)|uniprotkb:CELE_W09G10.3(orf name)|uniprotkb:ncs-6(gene name)|psi-mi:ncs-6(display_short)|uniprotkb:W09G10.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530953|imex:IM-18681-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) ensemblmetazoa:W09G10.3.1(transcript)|ensemblmetazoa:WBGene00021116(gene)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_494569.1|wormbase:W09G10.3|interpro:IPR028846|reactome:R-CEL-5576894|uniprotkb:O16638(identity)|wormbase:WBGene00021116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:PcmCg6FfCDBBtkQU1ik81LAOIlg6239 intact-crc:2D1D153032CC39DE|rigid:pA+cd0jKr3y0dYFztnEaogdny7E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:O02174 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-2315779|ensemblmetazoa:W05H7.4a.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:o02174_caeel(display_long)|uniprotkb:zfp-3(gene name)|psi-mi:zfp-3(display_short)|uniprotkb:CELE_W05H7.4(orf name)|uniprotkb:W05H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530938|imex:IM-18681-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_741720.2|wormbase:W05H7.4a|dip:DIP-24700N|ensemblmetazoa:W05H7.4a.1(transcript)|ensemblmetazoa:WBGene00021047(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|uniprotkb:O02174(identity)|wormbase:WBGene00021047(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:R0h2ws5KoHLO1xjsdYiNFhPwqWM6239 intact-crc:2AD52AA50D77BB17|rigid:D7NO0+GsciIQ48hBUCXWU9buIck false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XTW8 uniprotkb:G5ED33 intact:EBI-6530860|ensemblmetazoa:H12D21.6.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:q9xtw8_caeel(display_long)|uniprotkb:CELE_H12D21.6(orf name)|uniprotkb:H12D21.6(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530856|imex:IM-18681-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:H12D21.6.1(transcript)|ensemblmetazoa:WBGene00010382(gene)|refseq:NP_506673.1|wormbase:H12D21.6|uniprotkb:Q9XTW8(identity)|wormbase:WBGene00010382(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JYHf3Js7/LToOz5I8cieOuH/gMQ6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:853B6B30F1130692|rigid:i3kVjDOzm/gKsQfDo+6tEdhb+XA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:Q22387 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530910|imex:IM-18681-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 intact-crc:C056B131EBC39D14|rigid:vMBQkxZcVVKp6KvHia+ff2GGZVo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:P45972 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-319208|ensemblmetazoa:T09A5.12.1|ensemblmetazoa:T09A5.12.2 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:ztf17_caeel(display_long)|uniprotkb:T09A5.12(orf name)|uniprotkb:ztf-17(gene name)|psi-mi:ztf-17(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530897|imex:IM-18681-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_495656.2|ensemblmetazoa:T09A5.12.1(transcript)|ensemblmetazoa:T09A5.12.2(transcript)|ensemblmetazoa:WBGene00011639(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|reactome:R-CEL-9018519|wormbase:T09A5.12|mint:P45972|dip:DIP-25547N|uniprotkb:P45972(identity)|wormbase:WBGene00011639(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:Jbr7OzyYPx/MQ5pGf0AbCedU0BU6239 intact-crc:33DB9D03C0ABCCBE|rigid:a4u6oxhXz7wWYy3b80HpCtzvT1k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22227 uniprotkb:G5ED33 intact:EBI-316403|ensemblmetazoa:T05C12.6a.1|intact:EBI-2315994|intact:EBI-2924320|uniprotkb:G5EC49|uniprotkb:O76471|uniprotkb:Q95ZQ0 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:mig5_caeel(display_long)|uniprotkb:Abnormal cell migration protein 5(gene name synonym)|uniprotkb:T05C12.6(orf name)|uniprotkb:mig-5(gene name)|psi-mi:mig-5(display_short) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530884|imex:IM-18681-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-5663220|refseq:NP_001022316.1|wormbase:T05C12.6a|ensemblmetazoa:T05C12.6a.1(transcript)|ensemblmetazoa:WBGene00003241(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001709"(cell fate determination)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0016477"(cell migration)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030054"(cell junction)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040039"(inductive cell migration)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060069"(Wnt signaling pathway, regulating spindle positioning)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060573"(cell fate specification involved in pattern specification)|go:"GO:0070986"(left/right axis specification)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|go:"GO:0048730"(epidermis morphogenesis)|refseq:NP_001022317.1|refseq:NP_001022318.1|wormbase:T05C12.6b|wormbase:T05C12.6c|dip:DIP-27038N|reactome:R-CEL-201688|reactome:R-CEL-4086400|reactome:R-CEL-4641258|reactome:R-CEL-5099900|reactome:R-CEL-2028269|reactome:R-CEL-4641262|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:G5EC49(identity)|wormbase:WBGene00003241(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:Pp8SAvLL8oifjCuQDA+XKc3EON86239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:F39F37484E99AF8C|rigid:sBxAYRU5TOzpaoP3M06Msp6oSto false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:A0PD34 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-6530923|ensemblmetazoa:VM106R.1.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:a0pd34_caeel(display_long)|uniprotkb:CELE_VM106R.1(orf name)|uniprotkb:VM106R.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530925|imex:IM-18681-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) reactome:R-CEL-8951664|reactome:R-CEL-983168|ensemblmetazoa:VM106R.1.1(transcript)|ensemblmetazoa:WBGene00014848(gene)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0043235"(receptor complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|wormbase:VM106R.1|refseq:NP_001076634.1|uniprotkb:A0PD34(identity)|wormbase:WBGene00014848(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/04/25 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:sDo88x3C6U8uNtCCNcGd2TgVKU86239 intact-crc:A593DA3D207923F4|rigid:pyRUm2MWKiIM9Z6JvK64dWbceKU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:G5ECG0 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530994|imex:IM-18681-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3|uniprotkb:G5ECG0(identity)|wormbase:WBGene00006381(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 intact-crc:2B03C3C07CBAF2F1|rigid:RA74My7kFLI55wqPQKCZfQRgWSE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:G5ED33 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531007|imex:IM-18681-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:A1A3BC21879C4BA8|rigid:ztw7FDm+lvUM8EBvK1K7/ew+Jlk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:Q9N2Z7 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-317369|uniprotkb:Q95XU3|uniprotkb:V6CJJ8|uniprotkb:V6CLY4|ensemblmetazoa:Y65B4BR.4a.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:wwp1_caeel(display_long)|uniprotkb:wwp-1(gene name)|psi-mi:wwp-1(display_short)|uniprotkb:Y65B4BR.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531020|imex:IM-18681-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) wormbase:Y65B4BR.4b|wormbase:Y65B4BR.4c|wormbase:Y65B4BR.4d|refseq:NP_740775.1|wormbase:Y65B4BR.4a|ensemblmetazoa:WBGene00007009(gene)|ensemblmetazoa:Y65B4BR.4a.1(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|reactome:R-CEL-1253288|reactome:R-CEL-983168|reactome:R-CEL-9013406|reactome:R-CEL-9013420|refseq:NP_001293271.1|refseq:NP_001293272.1|refseq:NP_740776.1|dip:DIP-25758N|reactome:R-CEL-2672351|reactome:R-CEL-8948751|reactome:R-CEL-5610780|reactome:R-CEL-5632684|uniprotkb:Q95XU3(identity)|wormbase:WBGene00007009(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2021/06/18 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:PlZNO3kcb422riUzp2aLH7Xaz3E6239 intact-crc:13B343F3705CE5FC|rigid:zR2wNd4YeSi5VECB8Zpp3WcxB4U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q4VNJ8 uniprotkb:G5ED33 intact:EBI-2918529 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531033|imex:IM-18681-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:299FB6861888E70A|rigid:SEmKs1BqNyDOOZ/6WYEA/bH1Fl8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q94398 uniprotkb:G5ED33 intact:EBI-2421006|ensemblmetazoa:ZK265.4a.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:hm08_caeel(display_long)|uniprotkb:ZK265.4(orf name)|uniprotkb:ceh-8(gene name)|psi-mi:ceh-8(display_short) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531046|imex:IM-18681-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492246.2|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|wormbase:ZK265.4a|interpro:IPR032967|ensemblmetazoa:WBGene00000433(gene)|ensemblmetazoa:ZK265.4a.1(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|uniprotkb:Q94398(identity)|wormbase:WBGene00000433(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:UWuIIAYSxjfjYVl9sYxRRHlWeL46239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:1B2CA33FEB682BA2|rigid:jNLj5FFsAmtGEjmhMlnPrUEPmVQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16299 uniprotkb:O16299 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531059|imex:IM-18681-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 intact-crc:9703AE56FA60ED19|rigid:C8RRGtC3/hQoIrEcUYrthSvxMmI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16299 uniprotkb:P55853 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531072|imex:IM-18681-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933|uniprotkb:P55853(identity)|wormbase:WBGene00004888(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 intact-crc:C7502B86DEB41C9E|rigid:M/o9O7XCun3PI9r1dbGd0FAHFjc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q11088 uniprotkb:Q1XFY2 intact:EBI-6531085|ensemblmetazoa:C01C4.1.1|ensemblmetazoa:C01C4.1.2 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 psi-mi:nlp1_caeel(display_long)|uniprotkb:nlp-1(gene name)|psi-mi:nlp-1(display_short)|uniprotkb:C01C4.1(orf name) psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531087|imex:IM-18681-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C01C4.1.1(transcript)|ensemblmetazoa:C01C4.1.2(transcript)|ensemblmetazoa:WBGene00003739(gene)|go:"GO:0001966"(thigmotaxis)|go:"GO:0071244"(cellular response to carbon dioxide)|go:"GO:1903745"(negative regulation of pharyngeal pumping)|refseq:NP_508640.1|wormbase:C01C4.1|uniprotkb:Q11088(identity)|wormbase:WBGene00003739(identity) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MrQt5LxzwpRxugcN6gtlxY/JvWg6239 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 intact-crc:1CD98E9D30B81757|rigid:W2vcn1fiMHrjIJHw1h7Am37j0Is false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:Q9N4V4 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-6530979|ensemblmetazoa:Y47D9A.2a.1|uniprotkb:Q86S75 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:scpl3_caeel(display_long)|uniprotkb:scpl-3(gene name)|psi-mi:scpl-3(display_short)|uniprotkb:Y47D9A.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6530981|imex:IM-18681-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) ensemblmetazoa:WBGene00021629(gene)|ensemblmetazoa:Y47D9A.2a.1(transcript)|go:"GO:0004721"(phosphoprotein phosphatase activity)|interpro:IPR004274(NLI interacting factor)|interpro:IPR011948(Dullard-like phosphatase domain)|interpro:IPR023214|refseq:NP_491348.1|wormbase:Y47D9A.2a|interpro:IPR036412|uniprotkb:Q9N4V4(identity)|wormbase:WBGene00021629(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:dtYQ3sdHJ99+0fTJcuHW6h5Alls6239 intact-crc:F516008AA4A0FA34|rigid:ch+LIuCPlay2NvWOGfWfld5k+qY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1XFY2 uniprotkb:Q22752 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 intact:EBI-328280|ensemblmetazoa:T24H10.6.1 psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:q22752_caeel(display_long)|uniprotkb:dyrb-1(gene name)|psi-mi:dyrb-1(display_short)|uniprotkb:T24H10.6(orf name)|uniprotkb:CELE_T24H10.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531115|imex:IM-18681-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) refseq:NP_495943.1|wormbase:T24H10.6|reactome:R-CEL-5620924|dip:DIP-24279N|ensemblmetazoa:T24H10.6.1(transcript)|ensemblmetazoa:WBGene00012004(gene)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR004942(Dynein light chain-related)|interpro:IPR016561(Dynein light chain, roadblock-type)|go:"GO:0005813"(centrosome)|uniprotkb:Q22752(identity)|wormbase:WBGene00012004(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 rogid:hSEbK1Z9HGIG7/GWt6ajVc4zadI6239 intact-crc:A8E313D782C6C274|rigid:gBkl8AffkQaFdL0mnrJ1PqCeR9I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18060 uniprotkb:Q95QA6 intact:EBI-6531207|ensemblmetazoa:C17C3.4.1 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 psi-mi:ilg1_caeel(display_long)|uniprotkb:ins-11(gene name)|psi-mi:ins-11(display_short)|uniprotkb:Ceinsulin-3(gene name synonym)|uniprotkb:C17C3.4(orf name) psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531203|imex:IM-18681-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C17C3.4.1(transcript)|ensemblmetazoa:WBGene00002094(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0045087"(innate immune response)|interpro:IPR022353|refseq:NP_495071.1|wormbase:C17C3.4|interpro:IPR036438|uniprotkb:Q18060(identity)|wormbase:WBGene00002094(identity) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:xJE5zCK9nhoq/j6PUC35jci38L46239 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 intact-crc:45394069D4A28B6B|rigid:P6sNmCDSLCDgQCpaVyvdeeKm808 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17956 uniprotkb:Q95QA6 intact:EBI-6531192|ensemblmetazoa:C14A4.9.1 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 psi-mi:q17956_caeel(display_long)|uniprotkb:CELE_C14A4.9(orf name)|uniprotkb:C14A4.9(orf name) psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531188|imex:IM-18681-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C14A4.9.1(transcript)|ensemblmetazoa:WBGene00007560(gene)|refseq:NP_496288.1|wormbase:C14A4.9|uniprotkb:Q17956(identity)|wormbase:WBGene00007560(identity) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:uIwEaRqh8BSNtJjOEv7OgNPpUHA6239 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 intact-crc:4FAA23300897BD6A|rigid:mhjgfLdhhbC0aOmWlzdbqOjF02o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U3Q7 uniprotkb:Q95QA6 intact:EBI-6531171|ensemblmetazoa:C08F11.7.1 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 psi-mi:q9u3q7_caeel(display_long)|uniprotkb:CELE_C08F11.7(orf name)|uniprotkb:C08F11.7(orf name) psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531175|imex:IM-18681-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C08F11.7.1(transcript)|ensemblmetazoa:WBGene00007454(gene)|interpro:IPR006570(SPK)|refseq:NP_502632.1|wormbase:C08F11.7|uniprotkb:Q9U3Q7(identity)|wormbase:WBGene00007454(identity) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:b70Lobuu/prLNyPHw72Q9R6esEo6239 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 intact-crc:34291CB4C507BB77|rigid:DSr0o17S9xzEkSjDR6o5wk5tyXc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U1N6 uniprotkb:Q1XFY2 intact:EBI-6531156|ensemblmetazoa:ZK792.8.1 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 psi-mi:atg42_caeel(display_long)|uniprotkb:atg-4.2(gene name)|psi-mi:atg-4.2(display_short)|uniprotkb:Autophagy-related protein 4 homolog 2(gene name synonym)|uniprotkb:ZK792.8(orf name) psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531158|imex:IM-18681-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00014080(gene)|ensemblmetazoa:ZK792.8.1(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006508"(proteolysis)|go:"GO:0006914"(autophagy)|go:"GO:0015031"(protein transport)|interpro:IPR005078(Peptidase C54)|refseq:NP_502208.1|wormbase:ZK792.8|interpro:IPR038765|reactome:R-CEL-1632852|uniprotkb:Q9U1N6(identity)|wormbase:WBGene00014080(identity) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:PUcNJVsqVd35dVUZS6rQo33j1Sg6239 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 intact-crc:DD1C31A03974058A|rigid:fo+ozV3DwqnWFQoua+YqintRnag false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1XFY2 uniprotkb:Q9XWP7 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 intact:EBI-2421234|ensemblmetazoa:Y40B1B.5.1 psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:q9xwp7_caeel(display_long)|uniprotkb:eif-3.J(gene name synonym)|uniprotkb:eif-3.j(gene name)|psi-mi:eif-3.j(display_short)|uniprotkb:CELE_Y40B1B.5(orf name)|uniprotkb:Y40B1B.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531143|imex:IM-18681-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) interpro:IPR013906(Translation initiation factor eIF3 subunit)|refseq:NP_493365.1|wormbase:Y40B1B.5|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|interpro:IPR023194|ensemblmetazoa:WBGene00012738(gene)|ensemblmetazoa:Y40B1B.5.1(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|uniprotkb:Q9XWP7(identity)|wormbase:WBGene00012738(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 rogid:3FaI0PqKq4WKDoEa7yoJ7NMvxkE6239 intact-crc:0DE0DD31228182BC|rigid:yWUf0Kwlv5v9pVF5m7AMk8Ay9hQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A5PEW5 uniprotkb:Q1XFY2 intact:EBI-6531128|ensemblmetazoa:Y22F5A.3b.1 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 psi-mi:a5pew5_caeel(display_long)|uniprotkb:Y22F5A.3(orf name)|uniprotkb:ric-4(gene name)|psi-mi:ric-4(display_short)|uniprotkb:CELE_Y22F5A.3(orf name) psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531130|imex:IM-18681-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-8980692|reactome:R-CEL-9013149|reactome:R-CEL-9013406|reactome:R-CEL-9035034|reactome:R-CEL-6798695|ensemblmetazoa:WBGene00004364(gene)|ensemblmetazoa:Y22F5A.3b.1(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0098793"(presynapse)|reactome:R-CEL-449836|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|refseq:NP_001123033.1|wormbase:Y22F5A.3b|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|reactome:R-CEL-888590|wormbase:WBGene00004364(identity)|uniprotkb:A5PEW5(identity) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:9C0tYmnF6vDSpob3U0C6hMHSluU6239 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 intact-crc:DE58E7A733F9A79D|rigid:YUXJOLKbwRPTFWSlzCQMNFgTwZs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q38G52 uniprotkb:Q1XFY2 intact:EBI-6531104|ensemblmetazoa:F23A7.8.1 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 psi-mi:q38g52_caeel(display_long)|uniprotkb:CELE_F23A7.8(orf name)|uniprotkb:F23A7.8(orf name) psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531100|imex:IM-18681-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F23A7.8.1(transcript)|ensemblmetazoa:WBGene00044638(gene)|refseq:NP_001033542.1|wormbase:F23A7.8|uniprotkb:Q38G52(identity)|wormbase:WBGene00044638(identity) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:08t8o1HdfdDqVXYcNmLYU8i4gzY6239 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 intact-crc:F045CD100677C662|rigid:lfhspU27PyN8KF05HNoh1Hy5ItU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:Q9XUJ5 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-6531330|ensemblmetazoa:W09D6.4.1 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:q9xuj5_caeel(display_long)|uniprotkb:CELE_W09D6.4(orf name)|uniprotkb:W09D6.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531332|imex:IM-18681-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) ensemblmetazoa:W09D6.4.1(transcript)|ensemblmetazoa:WBGene00012357(gene)|refseq:NP_499427.1|wormbase:W09D6.4|uniprotkb:Q9XUJ5(identity)|wormbase:WBGene00012357(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:rl4JgpQHuIkjc8i8u6krfy4o3nE6239 intact-crc:1890C0897E0618A0|rigid:VUaDl3oKAxMWoNdlJbIxVBdi+RQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:Q94071 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-2418600|uniprotkb:A0A131MBC5|uniprotkb:A0A131MBE2|uniprotkb:A0A131MBV4|uniprotkb:A0A131MBW2|uniprotkb:A0A131MBW4|uniprotkb:A0A131MBY3|uniprotkb:A0A131MBZ3|uniprotkb:A0A131MC19|uniprotkb:A0A131MC32|uniprotkb:A0A131MCT0|uniprotkb:A0A131MD42|uniprotkb:A0A131MD54|uniprotkb:A0A131MD98|uniprotkb:A0A131MDA8|uniprotkb:A0A131MDI4|uniprotkb:A0A131MDJ4|uniprotkb:A7LPI2|uniprotkb:Q94075|ensemblmetazoa:T21H8.1h.1 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:lipb_caeel(display_long)|uniprotkb:hlb-1(gene name)|psi-mi:hlb-1(display_short)|uniprotkb:LAR-interacting protein beta(gene name synonym)|uniprotkb:T21H8.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531317|imex:IM-18681-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) refseq:NP_001309707.1|refseq:NP_001309708.1|refseq:NP_001309709.1|refseq:NP_001309710.1|refseq:NP_001309711.1|refseq:NP_001309712.1|refseq:NP_001309713.1|wormbase:T21H8.1p|refseq:NP_001309714.1|refseq:NP_001309705.1|interpro:IPR037619|refseq:NP_001123185.1|refseq:NP_001309703.1|refseq:NP_001309704.1|refseq:NP_001309706.1|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030444|interpro:IPR037617|interpro:IPR037618|reactome:R-CEL-388844|refseq:NP_510311.2|wormbase:T21H8.1a|wormbase:T21H8.1b|wormbase:T21H8.1c|wormbase:T21H8.1d|wormbase:T21H8.1e|wormbase:T21H8.1f|wormbase:T21H8.1g|wormbase:T21H8.1h|wormbase:T21H8.1i|wormbase:T21H8.1j|wormbase:T21H8.1k|wormbase:T21H8.1l|wormbase:T21H8.1m|wormbase:T21H8.1n|wormbase:T21H8.1o|wormbase:T21H8.1q|wormbase:T21H8.1r|wormbase:T21H8.1s|refseq:NP_001309715.1|refseq:NP_001309716.1|refseq:NP_001309717.1|refseq:NP_001309718.1|refseq:NP_510312.1|ensemblmetazoa:T21H8.1h.1(transcript)|ensemblmetazoa:WBGene00011904(gene)|go:"GO:0000003"(reproduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0043051"(regulation of pharyngeal pumping)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|uniprotkb:Q94075(identity)|wormbase:WBGene00011905(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/09/20 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:Al9kmnFuVtUlSZ9hmmnI/tB8suA6239 intact-crc:2DF4BFF83DFA83DD|rigid:/EWJofxHkN3DZGmaHkfP9o8SS9s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:P91485 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-6531302|ensemblmetazoa:T21E12.5.1 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:p91485_caeel(display_long)|uniprotkb:CELE_T21E12.5(orf name)|uniprotkb:T21E12.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531304|imex:IM-18681-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) ensemblmetazoa:T21E12.5.1(transcript)|ensemblmetazoa:WBGene00020656(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_491366.1|wormbase:T21E12.5|uniprotkb:P91485(identity)|wormbase:WBGene00020656(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:dVpHzxEa7JfkJS/mCxwHCYg/ACQ6239 intact-crc:089D6815711E8DD2|rigid:1XrOYNP2FHKsfenog7uJtUbQVec false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:Q22159 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-6531291|ensemblmetazoa:T04F3.4.1 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:q22159_caeel(display_long)|uniprotkb:CELE_T04F3.4(orf name)|uniprotkb:T04F3.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531287|imex:IM-18681-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) ensemblmetazoa:T04F3.4.1(transcript)|ensemblmetazoa:WBGene00011439(gene)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_505966.1|wormbase:T04F3.4|uniprotkb:Q22159(identity)|wormbase:WBGene00011439(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:NkFsFIDZEDKVXJkus7K+tchsi6w6239 intact-crc:4213D81BF056D985|rigid:EB2opDlfyPaW6r3cOH5YHZKpMiU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:Q21648 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531274|imex:IM-18681-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 intact-crc:89DF99CE0CC45308|rigid:9TVCsIDJD+xjt0dFDJ9q6Gs3L0Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ13 uniprotkb:Q95QA6 intact:EBI-6530841|ensemblmetazoa:F59F3.6.1 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 psi-mi:q8mq13_caeel(display_long)|uniprotkb:CELE_F59F3.6(orf name)|uniprotkb:F59F3.6(orf name) psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531261|imex:IM-18681-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F59F3.6.1(transcript)|ensemblmetazoa:WBGene00010335(gene)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_741899.1|wormbase:F59F3.6|uniprotkb:Q8MQ13(identity)|wormbase:WBGene00010335(identity) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:cWBLR2mBejFpPZRal6w69itlyRw6239 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 intact-crc:34E52D701A5ED058|rigid:Y43f/PDMmQ40kLht0+ovg08Gnh8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20027 uniprotkb:Q95QA6 intact:EBI-323456|ensemblmetazoa:F35C8.5.1 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 psi-mi:c25hl_caeel(display_long)|uniprotkb:F35C8.5(orf name) psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531248|imex:IM-18681-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508912.1|wormbase:F35C8.5|reactome:R-CEL-192105|ensemblmetazoa:F35C8.5.1(transcript)|ensemblmetazoa:WBGene00018036(gene)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|dip:DIP-27397N|uniprotkb:Q20027(identity)|wormbase:WBGene00018036(identity) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:PKSrSr8R4zZ4Ri1cLVIvK3tgeLA6239 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 intact-crc:5B33676F87EAD8F7|rigid:02dpqiC2gFVCHCXPXAQZbM+jgu0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P90754 uniprotkb:Q95QA6 intact:EBI-6531218|ensemblmetazoa:C27A7.1a.1|uniprotkb:Q2PJ70 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 psi-mi:enpp1_caeel(display_long)|uniprotkb:C27A7.1(orf name) psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531220|imex:IM-18681-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029897|ensemblmetazoa:C27A7.1a.1(transcript)|ensemblmetazoa:WBGene00007753(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|refseq:NP_001041085.1|refseq:NP_001041086.1|wormbase:C27A7.1a|wormbase:C27A7.1b|reactome:R-CEL-196843|uniprotkb:P90754(identity)|wormbase:WBGene00007753(identity) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:yyW68PKP5DW3LH7Q87o5ZFJ/UpU6239 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 intact-crc:D75664715E97726F|rigid:l2uIry6b9mFnFR/p5HnQojOxd5I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:Q19065 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-6531237|ensemblmetazoa:E04F6.10.1 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:q19065_caeel(display_long)|uniprotkb:CELE_E04F6.10(orf name)|uniprotkb:E04F6.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531233|imex:IM-18681-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) ensemblmetazoa:E04F6.10.1(transcript)|ensemblmetazoa:WBGene00017129(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_495504.2|wormbase:E04F6.10|uniprotkb:Q19065(identity)|wormbase:WBGene00017129(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:xuG/sojspue3Jt8hLsGYXn6Ev/86239 intact-crc:7EF71382A9748FD7|rigid:V55WF1nGZJ3UDzwteA29x2v3HY0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22463 uniprotkb:Q22387 intact:EBI-6531416|ensemblmetazoa:T13H2.5b.1 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 psi-mi:q22463_caeel(display_long)|uniprotkb:CELE_T13H2.5(orf name)|uniprotkb:spat-3(gene name)|psi-mi:spat-3(display_short)|uniprotkb:T13H2.5(orf name) psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531418|imex:IM-18681-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T13H2.5b.1(transcript)|ensemblmetazoa:WBGene00020496(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|refseq:NP_001024905.1|wormbase:T13H2.5b|interpro:IPR043540|uniprotkb:Q22463(identity)|wormbase:WBGene00020496(identity) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:OPfFXv1tgjbu1IQuLdxOB8/zDoM6239 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 intact-crc:6FCEE9F166D5EC02|rigid:WPMjIyLMzbFUqy9Aw3aYiwKXto4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22387 uniprotkb:Q22387 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531403|imex:IM-18681-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 intact-crc:C9DE50F54F575A02|rigid:tmI7C0hq2DfUy+CdcR4puGu0VgY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22387 intact:EBI-322747 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 - psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:q21036_caeel(display_short)|psi-mi:EBI-322747(display_long)|uniprotkb:F59C12.3(orf name)|uniprotkb:CELE_F59C12.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531390|imex:IM-18681-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) uniprotkb:Q21036(uniprot-removed-ac)|uniprotkb:Q21036(identity)|wormbase:WBGene00019102(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 rogid:dVWt++lLXz7Z38h7fgnXA+5nlP06239 intact-crc:3003036F4213FA94|rigid:P4tvVIUY/B/wOnrsq/RSKd2/qJE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:H2KZH8 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-6531379|ensemblmetazoa:ZC416.1.1 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:h2kzh8_caeel(display_long)|uniprotkb:ZC416.1(orf name)|uniprotkb:madf-9(gene name)|psi-mi:madf-9(display_short)|uniprotkb:CELE_ZC416.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531375|imex:IM-18681-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) ensemblmetazoa:WBGene00022608(gene)|ensemblmetazoa:ZC416.1.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_500389.2|interpro:IPR006578(MADF)|wormbase:ZC416.1|interpro:IPR039353|uniprotkb:H2KZH8(identity)|wormbase:WBGene00022608(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:KZiXM27C0hGZIoAya1lL79G/7ak6239 intact-crc:6C0C9721794742D3|rigid:NZ/tiq3pXYOK8ltzmpPNfZYx76g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NA26 uniprotkb:Q95QA6 intact:EBI-6531360|ensemblmetazoa:Y87G2A.10a.1 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 psi-mi:vps28_caeel(display_long)|uniprotkb:vps-28(gene name)|psi-mi:vps-28(display_short)|uniprotkb:ESCRT-I complex subunit VPS28(gene name synonym)|uniprotkb:Y87G2A.10(orf name) psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531362|imex:IM-18681-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00013598(gene)|ensemblmetazoa:Y87G2A.10a.1(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|reactome:R-CEL-917729|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017898|interpro:IPR017899|refseq:NP_493382.1|wormbase:Y87G2A.10a|interpro:IPR038358|interpro:IPR037202|interpro:IPR037206|uniprotkb:Q9NA26(identity)|wormbase:WBGene00013598(identity) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:8uSxCutdQa7RTy5oxo29IPuSDCw6239 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 intact-crc:CEE5F4B285151854|rigid:7mNwtGQhWqv6PUr21RTk0Gy7o5w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:Q86FN8 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-6531349|ensemblmetazoa:Y54G2A.11b.1 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:q86fn8_caeel(display_long)|uniprotkb:CELE_Y54G2A.11(orf name)|uniprotkb:Y54G2A.11(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531345|imex:IM-18681-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) ensemblmetazoa:WBGene00021876(gene)|ensemblmetazoa:Y54G2A.11b.1(transcript)|refseq:NP_001023489.1|wormbase:Y54G2A.11b|uniprotkb:Q86FN8(identity)|wormbase:WBGene00021876(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:eu78pNpejPEDiNFF8/tkIbin6Z06239 intact-crc:3EE9DD0AE6B4E858|rigid:MX3MdMS7dpOgmZnCKalFl9iwXAg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q11181 uniprotkb:G5EC72 intact:EBI-2316016|uniprotkb:Q8T3F3|uniprotkb:Q8T3F4|uniprotkb:Q8T3F5|ensemblmetazoa:C05D10.4b.1 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:ypc4_caeel(display_long)|uniprotkb:C05D10.4(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531446|imex:IM-18681-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498323.2|refseq:NP_498324.2|refseq:NP_741170.1|wormbase:C05D10.4a|wormbase:C05D10.4b|wormbase:C05D10.4c|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|ensemblmetazoa:C05D10.4b.1(transcript)|ensemblmetazoa:WBGene00015480(gene)|uniprotkb:Q11181(identity)|wormbase:WBGene00015480(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:msS16ZOpmue9+9+to7VFLPE1TM86239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:33C4BD6F276809E2|rigid:Rf/KGcUGG+6D6zhwlNyVoreIn+E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22387 uniprotkb:Q23600 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 intact:EBI-6531431|ensemblmetazoa:ZK809.5a.1 psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:q23600_caeel(display_long)|uniprotkb:CELE_ZK809.5(orf name)|uniprotkb:ZK809.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531433|imex:IM-18681-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) ensemblmetazoa:WBGene00014087(gene)|ensemblmetazoa:ZK809.5a.1(transcript)|refseq:NP_001023624.1|wormbase:ZK809.5a|uniprotkb:Q23600(identity)|wormbase:WBGene00014087(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 rogid:hP1vMQ0F5lMHzWCF6SBDYUrhT6c6239 intact-crc:75A213D778C14BBB|rigid:ntnLOxQISXL84E+r8h7k9TSkGaE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEG1 uniprotkb:G5EC72 intact:EBI-318121|ensemblmetazoa:T08D10.1.1 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:nfya1_caeel(display_long)|uniprotkb:nfya-1(gene name)|psi-mi:nfya-1(display_short)|uniprotkb:CAAT box DNA-binding protein subunit nfya-1(gene name synonym)|uniprotkb:T08D10.1(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531554|imex:IM-18681-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q20858(uniprot-removed-ac)|interpro:IPR001289(CCAAT-binding transcription factor, subunit B)|refseq:NP_509999.1|wormbase:T08D10.1|ensemblmetazoa:T08D10.1.1(transcript)|ensemblmetazoa:WBGene00011614(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|uniprotkb:G5EEG1(identity)|wormbase:WBGene00011614(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:dekljPhnw70StLHUZ6AXDDbi9ms6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:AD419EA358995AFA|rigid:zB9Kz1H+saT8xZ6TqCJE7Y2kAM4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q17865 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531461|imex:IM-18681-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:34B957674E4867BD|rigid:71/toJJYfhupLJax/P8e5ahuds8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22227 uniprotkb:G5EC72 intact:EBI-316403|ensemblmetazoa:T05C12.6a.1|intact:EBI-2315994|intact:EBI-2924320|uniprotkb:G5EC49|uniprotkb:O76471|uniprotkb:Q95ZQ0 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:mig5_caeel(display_long)|uniprotkb:Abnormal cell migration protein 5(gene name synonym)|uniprotkb:T05C12.6(orf name)|uniprotkb:mig-5(gene name)|psi-mi:mig-5(display_short) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531541|imex:IM-18681-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-5663220|refseq:NP_001022316.1|wormbase:T05C12.6a|ensemblmetazoa:T05C12.6a.1(transcript)|ensemblmetazoa:WBGene00003241(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001709"(cell fate determination)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0016477"(cell migration)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030054"(cell junction)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040039"(inductive cell migration)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060069"(Wnt signaling pathway, regulating spindle positioning)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060573"(cell fate specification involved in pattern specification)|go:"GO:0070986"(left/right axis specification)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|go:"GO:0048730"(epidermis morphogenesis)|refseq:NP_001022317.1|refseq:NP_001022318.1|wormbase:T05C12.6b|wormbase:T05C12.6c|dip:DIP-27038N|reactome:R-CEL-201688|reactome:R-CEL-4086400|reactome:R-CEL-4641258|reactome:R-CEL-5099900|reactome:R-CEL-2028269|reactome:R-CEL-4641262|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:G5EC49(identity)|wormbase:WBGene00003241(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:Pp8SAvLL8oifjCuQDA+XKc3EON86239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:EC21702733217A00|rigid:NtfJhf2c9akraIYU3agGGyuzmSo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q20712 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-325968|ensemblmetazoa:F53B3.3.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:q20712_caeel(display_long)|uniprotkb:F53B3.3(orf name)|uniprotkb:CELE_F53B3.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531528|imex:IM-18681-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) refseq:NP_508497.3|wormbase:F53B3.3|ensemblmetazoa:F53B3.3.1(transcript)|ensemblmetazoa:WBGene00018742(gene)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|dip:DIP-25066N|uniprotkb:Q20712(identity)|wormbase:WBGene00018742(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:DVUtviRrC9eQgxhAF1NqxTYlHe86239 intact-crc:8645187F6C6E4CD0|rigid:RC7GGcp7Y+Khzq1DFIVc63QMMxU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q20398 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-322716|ensemblmetazoa:F44D12.1a.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:q20398_caeel(display_long)|uniprotkb:magu-4(gene name)|psi-mi:magu-4(display_short)|uniprotkb:F44D12.1(orf name)|uniprotkb:CELE_F44D12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531515|imex:IM-18681-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) ensemblmetazoa:F44D12.1a.1(transcript)|ensemblmetazoa:WBGene00009678(gene)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR027417|interpro:IPR035537|interpro:IPR036028|interpro:IPR036034|wormbase:F44D12.1a|dip:DIP-26684N|reactome:R-CEL-9013420|reactome:R-CEL-9013424|uniprotkb:Q20398(identity)|wormbase:WBGene00009678(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:yKOYpRav6wvmreffAp7m8Igoz7w6239 intact-crc:4207764491F60C16|rigid:6GvdR6O262QBUJ3FxAYOQ1lL2yw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E3W743 uniprotkb:G5EC72 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531500|imex:IM-18681-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:F52D3A1E08349E77|rigid:irM/OSiVhoRiq/U0mAWIUY94pDA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q8MNT0 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-324442|ensemblmetazoa:F28F5.3c.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:q8mnt0_caeel(display_long)|uniprotkb:lim-8(gene name)|psi-mi:lim-8(display_short)|uniprotkb:F28F5.3(orf name)|uniprotkb:CELE_F28F5.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531487|imex:IM-18681-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) refseq:NP_741201.1|wormbase:F28F5.3c|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|ensemblmetazoa:F28F5.3c.1(transcript)|ensemblmetazoa:WBGene00017904(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031430"(M band)|go:"GO:0032034"(myosin II head/neck binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|interpro:IPR036034|interpro:IPR041489|interpro:IPR029980|uniprotkb:Q8MNT0(identity)|wormbase:WBGene00017904(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:Prm6YPAZkkBApz/l8EwwI2JDZvk6239 intact-crc:74BC65A0125156C0|rigid:5trdRXnQiF7Ts7buGthVqqtT0dE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95ZV9 uniprotkb:G5EC72 intact:EBI-327570|ensemblmetazoa:F08F8.9a.2|ensemblmetazoa:F08F8.9a.1 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:q95zv9_caeel(display_long)|uniprotkb:F08F8.9(orf name)|uniprotkb:CELE_F08F8.9(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531474|imex:IM-18681-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498622.1|wormbase:F08F8.9a|ensemblmetazoa:F08F8.9a.2(transcript)|ensemblmetazoa:WBGene00017274(gene)|ensemblmetazoa:F08F8.9a.1(transcript)|dip:DIP-26979N|uniprotkb:Q95ZV9(identity)|wormbase:WBGene00017274(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:jwJXPQX/V2YFHWszVFrYOrcvLCU6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:10BA54496DE486DF|rigid:cHQmn/d7JdH6PfuReegssA+WeNk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q4VNJ8 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-2918529 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531658|imex:IM-18681-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 intact-crc:204782AE1DFAC694|rigid:uAEQ99lChafTuoVxWIcr6gvOpxw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:G5EC72 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531632|imex:IM-18681-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:B5CFB29766E07D54|rigid:mXo0lUt+AMXdvJSVujP7x/wYqs8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O18218 uniprotkb:G5EC72 intact:EBI-2429037|uniprotkb:O18217|ensemblmetazoa:Y53C12B.3a.1|ensemblmetazoa:Y53C12B.3a.2 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:o18218_caeel(display_long)|uniprotkb:nos-3(gene name)|psi-mi:nos-3(display_short)|uniprotkb:CELE_Y53C12B.3(orf name)|uniprotkb:Y53C12B.3(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531619|imex:IM-18681-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496102.1|wormbase:Y53C12B.3a|dip:DIP-26678N|ensemblmetazoa:WBGene00003785(gene)|ensemblmetazoa:Y53C12B.3a.1(transcript)|ensemblmetazoa:Y53C12B.3a.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|interpro:IPR024161|interpro:IPR038129|uniprotkb:O18218(identity)|wormbase:WBGene00003785(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:XPPh+BPm8Kf/DvBBydou2aG/brA6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:BE573EBEB016ED56|rigid:EF7kOsVaEGiSwF6pq1PNLsGzDkY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:O02174 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-2315779|ensemblmetazoa:W05H7.4a.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:o02174_caeel(display_long)|uniprotkb:zfp-3(gene name)|psi-mi:zfp-3(display_short)|uniprotkb:CELE_W05H7.4(orf name)|uniprotkb:W05H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531606|imex:IM-18681-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) refseq:NP_741720.2|wormbase:W05H7.4a|dip:DIP-24700N|ensemblmetazoa:W05H7.4a.1(transcript)|ensemblmetazoa:WBGene00021047(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|uniprotkb:O02174(identity)|wormbase:WBGene00021047(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:R0h2ws5KoHLO1xjsdYiNFhPwqWM6239 intact-crc:5D8752314F309200|rigid:lg7iZPNu6TEyQF0YwWSt7zbj8Mw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q23158 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-314014|ensemblmetazoa:W04D2.1a.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:q23158_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:CELE_W04D2.1(orf name)|uniprotkb:W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531593|imex:IM-18681-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) reactome:R-CEL-114608|reactome:R-CEL-446388|reactome:R-CEL-438066|reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_506127.1|wormbase:W04D2.1a|ensemblmetazoa:W04D2.1a.1(transcript)|ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0097433"(dense body)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|dip:DIP-25407N|uniprotkb:Q23158(identity)|wormbase:WBGene00000228(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:Iy6/ip1Rm3/Yb1HK7rHlSeScT006239 intact-crc:32D726422356B2C5|rigid:D8krAV1lGh2KGnewji0OA2V0NZU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:G5EC72 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531580|imex:IM-18681-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:F563F2680DA679F8|rigid:evdSEZFwq86bhVIgjE133IICiGs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:P45972 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-319208|ensemblmetazoa:T09A5.12.1|ensemblmetazoa:T09A5.12.2 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:ztf17_caeel(display_long)|uniprotkb:T09A5.12(orf name)|uniprotkb:ztf-17(gene name)|psi-mi:ztf-17(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531567|imex:IM-18681-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) refseq:NP_495656.2|ensemblmetazoa:T09A5.12.1(transcript)|ensemblmetazoa:T09A5.12.2(transcript)|ensemblmetazoa:WBGene00011639(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|reactome:R-CEL-9018519|wormbase:T09A5.12|mint:P45972|dip:DIP-25547N|uniprotkb:P45972(identity)|wormbase:WBGene00011639(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:Jbr7OzyYPx/MQ5pGf0AbCedU0BU6239 intact-crc:1D41300DA5C69187|rigid:5kQ4+Ryw+qvI876FDqQbegM/g+o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q9N312 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-2413781|ensemblmetazoa:Y61A9LA.9.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:q9n312_caeel(display_long)|uniprotkb:Y61A9LA.9(orf name)|uniprotkb:hpo-39(gene name)|psi-mi:hpo-39(display_short)|uniprotkb:CELE_Y61A9LA.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531645|imex:IM-18681-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) refseq:NP_504242.1|wormbase:Y61A9LA.9|ensemblmetazoa:WBGene00022020(gene)|ensemblmetazoa:Y61A9LA.9.1(transcript)|uniprotkb:Q9N312(identity)|wormbase:WBGene00022020(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:NPuTeMuvgJ9vwkhsdY8Tr3I2z4M6239 intact-crc:150D8544F90579D8|rigid:eHOPGcT7N44wgMhv1qHWDHfdwAg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q22866 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-329542|uniprotkb:Q22865|uniprotkb:Q27284|uniprotkb:Q7K6W7|uniprotkb:Q95Q31|ensemblmetazoa:Y105E8B.1a.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:tpm1_caeel(display_long)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:Y105E8B.1(orf name)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:tmy-1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531746|imex:IM-18681-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_001021695.1|refseq:NP_001021696.1|refseq:NP_001021698.1|refseq:NP_001021700.1|wormbase:Y105E8B.1a|wormbase:Y105E8B.1b|wormbase:Y105E8B.1d|wormbase:Y105E8B.1f|dip:DIP-27403N|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1a.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0034609"(spicule insertion)|go:"GO:0040011"(locomotion)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR000533(Tropomyosin)|reactome:R-CEL-445355|reactome:R-CEL-9013424|uniprotkb:Q22866(identity)|wormbase:WBGene00002978(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 22|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:4drvPtSXJSMiNn321+BRDOziZlE6239 intact-crc:CD873F175C0354FF|rigid:kFgjo16gufMqDx7PQFUVCLdiRMY false sufficient binding region:269-663 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q22257 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-321002|ensemblmetazoa:T06E4.1.1|ensemblmetazoa:T06E4.1.2 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:q22257_caeel(display_long)|uniprotkb:hcp-2(gene name)|psi-mi:hcp-2(display_short)|uniprotkb:CELE_T06E4.1(orf name)|uniprotkb:T06E4.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531731|imex:IM-18681-80 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_505489.1|wormbase:T06E4.1|ensemblmetazoa:T06E4.1.1(transcript)|ensemblmetazoa:T06E4.1.2(transcript)|ensemblmetazoa:WBGene00001830(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000776"(kinetochore)|go:"GO:0008104"(protein localization)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0051316"(attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation)|dip:DIP-24942N|uniprotkb:Q22257(identity)|wormbase:WBGene00001830(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:rpFN7NBLYg3MDFOByHIzSgrYQMw6239 intact-crc:365041AF32A1AEBA|rigid:s+npF4zQhuaLEMXbe+wzYL/GAcI false sufficient binding region:269-663 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P90901 uniprotkb:Q9U2T9 intact:EBI-322010|uniprotkb:G5ECT5|uniprotkb:Q17599|uniprotkb:Q20141|uniprotkb:Q8MLX8|uniprotkb:Q0G822|ensemblmetazoa:F38B2.1a.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:ifa1_caeel(display_long)|uniprotkb:ifa-1(gene name)|psi-mi:ifa-1(display_short)|uniprotkb:F38B2.1(orf name)|uniprotkb:Intermediate filament protein A1(gene name synonym)|uniprotkb:Cel IF A1(gene name synonym) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531716|imex:IM-18681-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F38B2.1d|refseq:NP_001076764.1|refseq:NP_741902.1|refseq:NP_741903.1|wormbase:F38B2.1a|wormbase:F38B2.1b|wormbase:F38B2.1c|ensemblmetazoa:F38B2.1a.1(transcript)|ensemblmetazoa:WBGene00002050(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|refseq:NP_001257139.1|dip:DIP-25729N|reactome:R-CEL-4419969|uniprotkb:P90901(identity)|wormbase:WBGene00002050(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 27|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:EkJ72CqvuJGe6NMmIhQ0GyyNZvM6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:B89AF29AE7708514|rigid:87JIzsqBkti8+KwY12UYqhP6jic false - sufficient binding region:269-663 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q17828 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-6531703|ensemblmetazoa:C08F8.2b.1|ensemblmetazoa:C08F8.2b.2|uniprotkb:Q2XN00|uniprotkb:E9P872 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:suv3_caeel(display_long)|uniprotkb:C08F8.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531699|imex:IM-18681-78 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) interpro:IPR044774|refseq:NP_001255542.1|ensemblmetazoa:C08F8.2b.1(transcript)|ensemblmetazoa:C08F8.2b.2(transcript)|ensemblmetazoa:WBGene00007444(gene)|go:"GO:0000965"(mitochondrial RNA 3'-end processing)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0045025"(mitochondrial degradosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR022192|refseq:NP_001040911.1|wormbase:C08F8.2b|interpro:IPR027417|interpro:IPR041082|interpro:IPR041453|refseq:NP_001040912.1|wormbase:C08F8.2c|uniprotkb:Q17828(identity)|wormbase:WBGene00007444(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/12/11 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:wecONsAlj/DrS25rL3K3p4a086E6239 intact-crc:065D85E2A173FAC6|rigid:OfIX7RMD97/6q17DBdUZl8G3xnc false sufficient binding region:269-663 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q09651 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-327687|ensemblmetazoa:ZK1307.9.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:cc130_caeel(display_long)|uniprotkb:ZK1307.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531684|imex:IM-18681-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) refseq:NP_496077.1|wormbase:ZK1307.9|ensemblmetazoa:WBGene00014250(gene)|ensemblmetazoa:ZK1307.9.1(transcript)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR007590(Protein of unknown function DUF572)|dip:DIP-24831N|uniprotkb:Q09651(identity)|wormbase:WBGene00014250(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 20|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:JCJk2zdUQwefTU5cCEKDyCmseUI6239 intact-crc:CD438FA5A1B62A1A|rigid:hIoeWPRsa7tljwL9xo4HAfYpfos false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4P3 uniprotkb:G5EC72 intact:EBI-317902|ensemblmetazoa:ZK121.2.1 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:q9n4p3_caeel(display_long)|uniprotkb:ZK121.2(orf name)|uniprotkb:CELE_ZK121.2(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531671|imex:IM-18681-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498142.1|wormbase:ZK121.2|ensemblmetazoa:WBGene00022664(gene)|go:"GO:0003676"(nucleic acid binding)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR036867|ensemblmetazoa:ZK121.2.1(transcript)|dip:DIP-25955N|uniprotkb:Q9N4P3(identity)|wormbase:WBGene00022664(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:1Rk77pcZ9juaD/8zbG1In+q+txE6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:2916B44369775CE5|rigid:qkdfD4ivWi6av9hgSUIKRZkHHis false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ70 uniprotkb:Q9U2T9 intact:EBI-6531842|ensemblmetazoa:F20B6.8b.1|uniprotkb:Q19632|uniprotkb:Q8MQ69 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:hipk_caeel(display_long)|uniprotkb:F20B6.8(orf name)|uniprotkb:hpk-1(gene name)|psi-mi:hpk-1(display_short) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531844|imex:IM-18681-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F20B6.8b.1(transcript)|ensemblmetazoa:WBGene00001994(gene)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009408"(response to heat)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0008340"(determination of adult lifespan)|refseq:NP_741761.1|refseq:NP_741763.1|wormbase:F20B6.8b|wormbase:F20B6.8c|reactome:R-CEL-3899300|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_741762.1|wormbase:F20B6.8a|reactome:R-CEL-8939243|uniprotkb:Q19632(identity)|wormbase:WBGene00001994(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/06/10 rogid:6efSd2oZvJzAMT7k7nEiclFAJm86239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:2308A1295B84123E|rigid:YUPL5qmli3iKjAc5L9HQHRLIIco false - sufficient binding region:1-275 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFF7 uniprotkb:Q9U2T9 intact:EBI-2416240|intact:EBI-6531829|uniprotkb:G5EC78|uniprotkb:G5EG66|ensemblmetazoa:F15C11.2a.1|ensemblmetazoa:F15C11.2a.2 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:ubql_caeel(display_long)|uniprotkb:ubql-1(gene name)|psi-mi:ubql-1(display_short)|uniprotkb:F15C11.2(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531825|imex:IM-18681-86 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q7JK76(uniprot-removed-ac)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|refseq:NP_740883.1|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|wormbase:F15C11.2b|wormbase:F15C11.2c|wormbase:F15C11.2a|interpro:IPR029071|reactome:R-CEL-8856825|interpro:IPR036353|refseq:NP_740884.1|refseq:NP_740885.1|ensemblmetazoa:F15C11.2a.1(transcript)|ensemblmetazoa:F15C11.2a.2(transcript)|ensemblmetazoa:WBGene00008852(gene)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|uniprotkb:G5EC78(identity)|wormbase:WBGene00008852(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 36|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/06/01 rogid:majcP8L4Ms62+PSs9xG8Lq1WfKk6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:116B7E21B43CB029|rigid:zoqGVd4CfKUplVk2mc7Q82qCe8g false - sufficient binding region:1-275 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XZI6 uniprotkb:Q9U2T9 intact:EBI-311866|uniprotkb:Q95Q72|uniprotkb:Q95Q73|uniprotkb:Q95Q74|uniprotkb:Q95Q75|uniprotkb:Q9UA04|uniprotkb:Q9UA05|uniprotkb:Q9XZI7|uniprotkb:Q9XZI8|uniprotkb:Q9XZI9|ensemblmetazoa:C32E8.10a.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:pical_caeel(display_long)|uniprotkb:C32E8.10(orf name)|uniprotkb:unc-11(gene name)|psi-mi:unc-11(display_short)|uniprotkb:AP180-like adaptor protein(gene name synonym)|uniprotkb:Uncoordinated protein 11(gene name synonym) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531810|imex:IM-18681-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C32E8.10a.1(transcript)|ensemblmetazoa:WBGene00006751(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0040011"(locomotion)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:1902683"(regulation of receptor localization to synapse)|go:"GO:1903539"(protein localization to postsynaptic membrane)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|refseq:NP_001021014.1|refseq:NP_001021015.1|refseq:NP_001021016.1|refseq:NP_491227.1|refseq:NP_491228.1|refseq:NP_491229.1|refseq:NP_491230.1|wormbase:C32E8.10a|wormbase:C32E8.10b|wormbase:C32E8.10c|wormbase:C32E8.10d|wormbase:C32E8.10e|wormbase:C32E8.10f|wormbase:C32E8.10h|reactome:R-CEL-432722|reactome:R-CEL-8856825|reactome:R-CEL-8856828|dip:DIP-25315N|uniprotkb:Q9XZI6(identity)|wormbase:WBGene00006751(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 35|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4JQIZTgKSv8kTdP9aYTzoTQp6L06239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:45B24D871568771A|rigid:hpGHUsUroJWgOxFADD60KZ5LmUE false - sufficient binding region:1-275 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q17935 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-2422875|ensemblmetazoa:C12D8.1a.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:q17935_caeel(display_long)|uniprotkb:fubl-1(gene name)|psi-mi:fubl-1(display_short)|uniprotkb:fubp-3.1(gene name synonym)|uniprotkb:C12D8.1(orf name)|uniprotkb:CELE_C12D8.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531795|imex:IM-18681-84 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_505632.1|wormbase:C12D8.1a|dip:DIP-26408N|ensemblmetazoa:C12D8.1a.1(transcript)|ensemblmetazoa:WBGene00007534(gene)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|uniprotkb:Q17935(identity)|wormbase:WBGene00007534(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:WPFhXTUsPVCUTMvGkJbIhfWB5ZU6239 intact-crc:DD21C31F14F30337|rigid:iuDigCB8Fmt+kiWc+YUsN68NbTI false sufficient binding region:1-275 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q9BIF4 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531780|imex:IM-18681-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 77|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/09 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 intact-crc:728BB1BEAF0A0A25|rigid:NotdZv8HV0ha4Mbrf59P8vlPz2E false sufficient binding region:269-663 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 intact:EBI-6531761 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 - psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:q45ej8_caeel(display_short)|psi-mi:EBI-6531761(display_long)|uniprotkb:ZC8.4(orf name)|uniprotkb:lfi-1(gene name)|psi-mi:lfi-1(display_short)|uniprotkb:CELE_ZC8.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531763|imex:IM-18681-82 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) uniprotkb:Q45EJ8(uniprot-removed-ac)|uniprotkb:Q45EJ8(identity)|wormbase:WBGene00022500(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:pYShjPnDAaWgY+24Sb9DCK7Ol8U6239 intact-crc:A6A9F5E0F2D3A291|rigid:nKajQiJFkXNhxRvObj2HQ52zg5o false sufficient binding region:269-663 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:G5EFY6 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-317770|ensemblmetazoa:T01G1.3.1|ensemblmetazoa:T01G1.3.2|ensemblmetazoa:T01G1.3.3 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:g5efy6_caeel(display_long)|uniprotkb:T01G1.3(orf name)|uniprotkb:sec-31(gene name)|psi-mi:sec-31(display_short)|uniprotkb:CELE_T01G1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531906|imex:IM-18681-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) uniprotkb:O45604(uniprot-removed-ac)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_502144.1|interpro:IPR040251|reactome:R-CEL-204005|wormbase:T01G1.3|ensemblmetazoa:T01G1.3.1(transcript)|ensemblmetazoa:T01G1.3.2(transcript)|ensemblmetazoa:T01G1.3.3(transcript)|ensemblmetazoa:WBGene00011338(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR036322|uniprotkb:G5EFY6(identity)|wormbase:WBGene00011338(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:FVZWQhc6ZjDGweaz8DeSFuMo9Zg6239 intact-crc:481C5C9005B877A1|rigid:Jufr0ynb1ek8rat3NsF2e5lv9QU false sufficient binding region:1-275 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q8MQ42 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-321247|ensemblmetazoa:F46H5.7b.1|ensemblmetazoa:F46H5.7b.2 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:q8mq42_caeel(display_long)|uniprotkb:F46H5.7(orf name)|uniprotkb:CELE_F46H5.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531859|imex:IM-18681-88 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) interpro:IPR014756(Immunoglobulin E-set)|refseq:NP_741830.1|wormbase:F46H5.7b|interpro:IPR032640|interpro:IPR013783(Immunoglobulin-like fold)|ensemblmetazoa:F46H5.7b.1(transcript)|ensemblmetazoa:F46H5.7b.2(transcript)|ensemblmetazoa:WBGene00018522(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0008380"(RNA splicing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0080090"(regulation of primary metabolic process)|interpro:IPR041105|interpro:IPR030077|uniprotkb:Q8MQ42(identity)|wormbase:WBGene00018522(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 28|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:4Bdt5s4xuKr9HfuaJg4vQ3kykZM6239 intact-crc:BDE4DF03F58E8039|rigid:N2FGYgWfEsCiQG2zTu4wWCwLH/s false sufficient binding region:1-275 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:A5JYR4 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-6531878|ensemblmetazoa:M110.5d.1|ensemblmetazoa:M110.5d.2 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:a5jyr4_caeel(display_long)|uniprotkb:M110.5(orf name)|uniprotkb:dab-1(gene name)|psi-mi:dab-1(display_short)|uniprotkb:CELE_M110.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531874|imex:IM-18681-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) ensemblmetazoa:M110.5d.1(transcript)|ensemblmetazoa:M110.5d.2(transcript)|ensemblmetazoa:WBGene00000894(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005938"(cell cortex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009306"(protein secretion)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0042395"(ecdysis, collagen and cuticulin-based cuticle)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR028761|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:M110.5d|refseq:NP_001122626.2|uniprotkb:A5JYR4(identity)|wormbase:WBGene00000894(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 87|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:GadYUGQwHYwYDpLsSMfrqqdgzRA6239 intact-crc:9FF7CBA3B24C0B93|rigid:2LqCuyv07IFPwtqLIGVIt70USYQ false sufficient binding region:1-275 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34552 uniprotkb:Q9U2T9 intact:EBI-322767|uniprotkb:Q7YXC7|uniprotkb:Q8I114|uniprotkb:Q8I115|uniprotkb:Q94159|ensemblmetazoa:R10E12.1b.1|ensemblmetazoa:R10E12.1b.2 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:alxa_caeel(display_long)|uniprotkb:alx-1(gene name)|psi-mi:alx-1(display_short)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 58"(gene name synonym)|uniprotkb:Protein YNK1(gene name synonym)|uniprotkb:pqn-58(gene name synonym)|uniprotkb:R10E12.1(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531891|imex:IM-18681-90 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022713.1|refseq:NP_001022714.1|refseq:NP_001022715.1|refseq:NP_499213.1|wormbase:R10E12.1a|wormbase:R10E12.1b|wormbase:R10E12.1c|wormbase:R10E12.1d|interpro:IPR004328(BRO1)|interpro:IPR025304|ensemblmetazoa:R10E12.1b.1(transcript)|ensemblmetazoa:R10E12.1b.2(transcript)|ensemblmetazoa:WBGene00007010(gene)|go:"GO:0005112"(Notch binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0007032"(endosome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043226"(organelle)|go:"GO:0055037"(recycling endosome)|interpro:IPR038499|uniprotkb:P34552(identity)|wormbase:WBGene00007010(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:xedXAHU8Ms6VcKj1w9YZDHURHHg6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:1F288E56CFC14226|rigid:PIdf77vJQ+09Zw74CV3s9zZcks8 false - sufficient binding region:1-275 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BI71 uniprotkb:Q9U2T9 intact:EBI-313770|ensemblmetazoa:T04C10.2b.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:q9bi71_caeel(display_long)|uniprotkb:epn-1(gene name)|psi-mi:epn-1(display_short)|uniprotkb:CELE_T04C10.2(orf name)|uniprotkb:T04C10.2(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531921|imex:IM-18681-92 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_510458.1|wormbase:T04C10.2b|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR003903(Ubiquitin interacting motif)|ensemblmetazoa:T04C10.2b.1(transcript)|ensemblmetazoa:WBGene00001329(gene)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|interpro:IPR027318|uniprotkb:Q9BI71(identity)|wormbase:WBGene00001329(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 19|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Aw70F0klLj4qD37NLNN8fD54oz06239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:CA2B24765E888E54|rigid:EL0EnhPXQVP/xCuG+hpKw7F2Q0A false - sufficient binding region:1-275 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BIF4 uniprotkb:Q9U2T9 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531966|imex:IM-18681-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 77|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/09 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:EA0C8C9D32016F97|rigid:NotdZv8HV0ha4Mbrf59P8vlPz2E false - sufficient binding region:1-275 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q09442 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531996|imex:IM-18681-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 20|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 intact-crc:4B1906182EA098F4|rigid:h7HyHn3MnBu31ZgEVDsgNQeAhYY false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:P39055 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531981|imex:IM-18681-96 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:3174556954D0C997|rigid:ywRBWRuRKHf0txogtfkUOnlKSRg false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q9U1W1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-315106|ensemblmetazoa:Y63D3A.5.1|ensemblmetazoa:Y63D3A.5.2 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:tfg_caeel(display_long)|uniprotkb:tfg-1(gene name)|psi-mi:tfg-1(display_short)|uniprotkb:Y63D3A.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531951|imex:IM-18681-94 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_493462.1|wormbase:Y63D3A.5|ensemblmetazoa:WBGene00006565(gene)|ensemblmetazoa:Y63D3A.5.1(transcript)|ensemblmetazoa:Y63D3A.5.2(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009306"(protein secretion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072595"(maintenance of protein localization in organelle)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|dip:DIP-26017N|reactome:R-CEL-204005|uniprotkb:Q9U1W1(identity)|wormbase:WBGene00006565(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:nqyc7+EyDkiVah2+12hsLFWeNdA6239 intact-crc:A89231E86BCA218C|rigid:DekU/mDI0dlluCVEKOjMFJKXM7s false sufficient binding region:1-275 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:G5ED84 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-312469|ensemblmetazoa:W02G9.2a.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:klhl8_caeel(display_long)|uniprotkb:kel-8(gene name)|psi-mi:kel-8(display_short)|uniprotkb:W02G9.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6531936|imex:IM-18681-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) uniprotkb:O61899(uniprot-removed-ac)|reactome:R-CEL-8951664|ensemblmetazoa:W02G9.2a.1(transcript)|ensemblmetazoa:WBGene00020952(gene)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|reactome:R-CEL-983168|wormbase:W02G9.2a|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|refseq:NP_503729.4|uniprotkb:G5ED84(identity)|wormbase:WBGene00020952(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:U6YpxxZM4gZixpdvsBb0hGIph9E6239 intact-crc:5246386881FEEE00|rigid:2/CXi43ngEilBTi1bmsCNa9Y0q4 false sufficient binding region:1-275 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q6BER5 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-313339|uniprotkb:B1Q274|uniprotkb:Q9NLC1|uniprotkb:O45407|uniprotkb:O45409|uniprotkb:O45410|uniprotkb:Q5WRM3|uniprotkb:Q95ZU8|ensemblmetazoa:F26H11.2c.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:nu301_caeel(display_long)|uniprotkb:nurf-1(gene name)|psi-mi:nurf-1(display_short)|uniprotkb:F26H11.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532073|imex:IM-18681-102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_001022117.2|refseq:NP_496994.3|refseq:NP_496995.3|refseq:NP_001022118.2|refseq:NP_001022119.1|refseq:NP_001022120.1|refseq:NP_001022121.1|refseq:NP_001122607.1|wormbase:F26H11.2a|wormbase:F26H11.2b|wormbase:F26H11.2c|wormbase:F26H11.2d|wormbase:F26H11.2e|wormbase:F26H11.2f|wormbase:F26H11.2g|wormbase:F26H11.2h|ensemblmetazoa:F26H11.2c.1(transcript)|ensemblmetazoa:WBGene00009180(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016589"(NURF complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR038028|dip:DIP-25937N|uniprotkb:Q6BER5(identity)|wormbase:WBGene00009180(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:rCyOD4/LtZMOytkoi61fcmGer/A6239 intact-crc:8D8455F6A619EEF1|rigid:WowHlS25sXnhArV3bM5lkCqdE8Y false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:P34397 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-321990|ensemblmetazoa:F10E9.3.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:ylu3_caeel(display_long)|uniprotkb:F10E9.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532058|imex:IM-18681-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_498826.2|wormbase:F10E9.3|ensemblmetazoa:F10E9.3.1(transcript)|ensemblmetazoa:WBGene00017355(gene)|interpro:IPR040437|dip:DIP-26529N|uniprotkb:P34397(identity)|wormbase:WBGene00017355(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:rI7gLX2TWTqguT53dk5CTySk7to6239 intact-crc:2D51072AE367D30A|rigid:TGB3xlq0OuMomESAXT2AcHKRSgs false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7JP65 uniprotkb:Q9U2T9 intact:EBI-6532045|ensemblmetazoa:F10D7.5b.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:q7jp65_caeel(display_long)|uniprotkb:CELE_F10D7.5(orf name)|uniprotkb:F10D7.5(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532041|imex:IM-18681-100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F10D7.5b.1(transcript)|ensemblmetazoa:WBGene00017342(gene)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006573(NEUZ)|refseq:NP_510817.3|wormbase:F10D7.5b|interpro:IPR037962|interpro:IPR043136|uniprotkb:Q7JP65(identity)|wormbase:WBGene00017342(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:dmeTGxA1egh7S0o5roMacNRvJzA6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:1947D9579CAE4F8A|rigid:lYV5caOQtXH6E1lvRZjUW9xvCEg false - sufficient binding region:657-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:P46582 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-319789|ensemblmetazoa:C34E10.8.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:sumv1_caeel(display_long)|uniprotkb:sumv-1(gene name)|psi-mi:sumv-1(display_short)|uniprotkb:Suppressor of synthetic multivulva protein 1(gene name synonym)|uniprotkb:C34E10.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532026|imex:IM-18681-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_498116.2|wormbase:C34E10.8|interpro:IPR025927|ensemblmetazoa:C34E10.8.1(transcript)|ensemblmetazoa:WBGene00016409(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|uniprotkb:P46582(identity)|wormbase:WBGene00016409(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:TfmDnsXbiby7iv1VQ3Zmg0TM5uA6239 intact-crc:425CE99CC543624D|rigid:/UbX2EEHBKjrMeUU0BcxoP83qEw false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93203 uniprotkb:Q9U2T9 intact:EBI-315294|ensemblmetazoa:C11E4.6.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:q93203_caeel(display_long)|uniprotkb:C11E4.6(orf name)|uniprotkb:CELE_C11E4.6(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532011|imex:IM-18681-98 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509620.2|wormbase:C11E4.6|ensemblmetazoa:C11E4.6.1(transcript)|ensemblmetazoa:WBGene00007520(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|dip:DIP-25879N|uniprotkb:Q93203(identity)|wormbase:WBGene00007520(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4lnus3cgxAI4dQDe0XjYAgmH2us6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:B16F0889902A7C12|rigid:UznG7unHWYOck4ib1ckZOqcJYiw false - sufficient binding region:657-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20010 uniprotkb:Q9U2T9 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532118|imex:IM-18681-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N|uniprotkb:Q20010(identity)|wormbase:WBGene00009385(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:11935935119D72FE|rigid:F3WKxyfqRcprZrmMBUwtR+269sg false - sufficient binding region:657-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ54 uniprotkb:Q9U2T9 intact:EBI-6532137|ensemblmetazoa:F41H10.3b.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:q8mq54_caeel(display_long)|uniprotkb:CELE_F41H10.3(orf name)|uniprotkb:F41H10.3(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532133|imex:IM-18681-106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F41H10.3b.1(transcript)|ensemblmetazoa:WBGene00018316(gene)|refseq:NP_741399.1|wormbase:F41H10.3b|uniprotkb:Q8MQ54(identity)|wormbase:WBGene00018316(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Ei30ijucb5I3E1KJNrxLkV6L4ow6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:3F65D28A1C3C7DEF|rigid:49hMum20FUWnjjYr3ol1AgFiHog false - sufficient binding region:657-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:G5ECW9 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-315316|ensemblmetazoa:F46F6.1a.1|ensemblmetazoa:F46F6.1a.2 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:g5ecw9_caeel(display_long)|uniprotkb:rme-4(gene name)|psi-mi:rme-4(display_short)|uniprotkb:F46F6.1(orf name)|uniprotkb:CELE_F46F6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532150|imex:IM-18681-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) uniprotkb:Q20473(uniprot-removed-ac)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|refseq:NP_509739.1|wormbase:F46F6.1a|mint:G5ECW9|ensemblmetazoa:F46F6.1a.1(transcript)|ensemblmetazoa:F46F6.1a.2(transcript)|ensemblmetazoa:WBGene00004375(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR043153|interpro:IPR040032|interpro:IPR037516|uniprotkb:G5ECW9(identity)|wormbase:WBGene00004375(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:3FE5ecvvghPRxJTDrlb8Ij9Vzx46239 intact-crc:BDE1AEC882030489|rigid:VUszMLTWYxLRo+SCAwtgTzhQonQ false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:E3W743 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532088|imex:IM-18681-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 intact-crc:E9997BF0DFB19E20|rigid:i3YnE2qDKpV6K+vEnZ083q3GOqM false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16299 uniprotkb:Q9U2T9 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532103|imex:IM-18681-104 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:6C71026A86E3D22F|rigid:bcJqmzHKDVV1D0O4nEKf+8kLjjA false - sufficient binding region:657-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:H2L045 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-325972|ensemblmetazoa:M01E11.7a.1|intact:EBI-2914896|uniprotkb:A0A0S4XR26|uniprotkb:A0A0S4XR31|uniprotkb:A0A0S4XR51|uniprotkb:A0A0S4XR69|uniprotkb:H2L046|uniprotkb:H2L047|uniprotkb:P92160 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:tensh_caeel(display_long)|uniprotkb:tag-163(gene name synonym)|uniprotkb:tns-1(gene name)|psi-mi:tns-1(display_short)|uniprotkb:M01E11.7(orf name)|uniprotkb:svh-6(gene name synonym)|uniprotkb:C1 domain-containing phosphatase and tensin homolog(gene name synonym)|uniprotkb:Suppressor of vhp-1 deletion lethality protein svh-6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532229|imex:IM-18681-112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) uniprotkb:Q95ZL4(uniprot-removed-ac)|wormbase:M01E11.7a|interpro:IPR000980(SH2 motif)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|refseq:NP_001305199.1|refseq:NP_001305202.1|refseq:NP_001305203.1|refseq:NP_001305204.1|ensemblmetazoa:M01E11.7a.1(transcript)|ensemblmetazoa:WBGene00006508(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0030054"(cell junction)|go:"GO:0030424"(axon)|go:"GO:0031430"(M band)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0055120"(striated muscle dense body)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|refseq:NP_491637.2|interpro:IPR033929|interpro:IPR035012|interpro:IPR036860|refseq:NP_491636.1|wormbase:M01E11.7b|wormbase:M01E11.7c|wormbase:M01E11.7d|wormbase:M01E11.7e|wormbase:M01E11.7f|wormbase:M01E11.7g|wormbase:M01E11.7h|refseq:NP_491638.1|refseq:NP_740854.1|interpro:IPR035892|uniprotkb:P92160(identity)|wormbase:WBGene00006508(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/03/02 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:RSgRFHcjsdUjIFspYSZicQHRRA06239 intact-crc:1E392B74A9BD7B96|rigid:PZRXVYQEDWuW3ADjKvHX5Q2bcPE false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL2 uniprotkb:Q9U2T9 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532212|imex:IM-18681-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 35|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:16167DAAD8060938|rigid:JEN4TFfXBtCrP4UkXvaAZnvCJ6E false - sufficient binding region:657-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:O01900 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532197|imex:IM-18681-110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 13|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 intact-crc:B4B59209C65804CE|rigid:2VTuYTqplNxQG/RjJiltr2ji6HU false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76337 uniprotkb:Q9U2T9 intact:EBI-6532169|ensemblmetazoa:F56D2.7.1|uniprotkb:O01421 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:ced6_caeel(display_long)|uniprotkb:ced-6(gene name)|psi-mi:ced-6(display_short)|uniprotkb:Candidate adapter protein ced-6(gene name synonym)|uniprotkb:F56D2.7(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532165|imex:IM-18681-108 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F56D2.7.1(transcript)|ensemblmetazoa:WBGene00000420(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012501"(programmed cell death)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0070986"(left/right axis specification)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|go:"GO:1904747"(positive regulation of apoptotic process involved in development)|go:"GO:0045335"(phagocytic vesicle)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_498203.2|wormbase:F56D2.7|uniprotkb:O76337(identity)|wormbase:WBGene00000420(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|wormbase:WBGene00006405(identity)|uniprotkb:E6N0W0(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VjlyH911QZCg4QZbyWiJu1i01cg6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:8C03CD9329D166A7|rigid:ek0SFsmnYUPMw7qtCasmFTSG+kY false - sufficient binding region:657-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20877 uniprotkb:Q9U2T9 intact:EBI-315480|ensemblmetazoa:F56D3.1.1|ensemblmetazoa:F56D3.1.2 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:q20877_caeel(display_long)|uniprotkb:F56D3.1(orf name)|uniprotkb:CELE_F56D3.1(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532182|imex:IM-18681-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494727.1|wormbase:F56D3.1|ensemblmetazoa:F56D3.1.1(transcript)|ensemblmetazoa:F56D3.1.2(transcript)|ensemblmetazoa:WBGene00018969(gene)|dip:DIP-24648N|uniprotkb:Q20877(identity)|wormbase:WBGene00018969(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:AUv5Clc1XXnuucrO63ViEf7UQV46239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:00A36EB52DF82CEB|rigid:cm5JV62UurlMYYjbz63IvIhOrJg false - sufficient binding region:657-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q6A573 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532304|imex:IM-18681-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:56D771D734703013|rigid:9cy3AybhwTqigG5/UL7YT5RCCeg false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWN1 uniprotkb:Q9U2T9 intact:EBI-324865|ensemblmetazoa:Y43F8C.6a.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:q9xwn1_caeel(display_long)|uniprotkb:Y43F8C.6(orf name)|uniprotkb:CELE_Y43F8C.6(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532289|imex:IM-18681-116 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256880.1|wormbase:Y43F8C.6a|ensemblmetazoa:WBGene00012828(gene)|ensemblmetazoa:Y43F8C.6a.1(transcript)|go:"GO:0016589"(NURF complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR037931|dip:DIP-27198N|uniprotkb:Q9XWN1(identity)|wormbase:WBGene00012828(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BnRBxnWaRRWRCAx+LGlNwRaOcOU6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:40432C1B7BBB83D1|rigid:s2F7G31SQYfl3vw5JCB39Hco6K0 false - sufficient binding region:657-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q9U304 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-329038|ensemblmetazoa:Y106G6D.7.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:q9u304_caeel(display_long)|uniprotkb:rbm-12(gene name)|psi-mi:rbm-12(display_short)|uniprotkb:CELE_Y106G6D.7(orf name)|uniprotkb:Y106G6D.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532274|imex:IM-18681-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_492671.1|wormbase:Y106G6D.7|dip:DIP-26480N|ensemblmetazoa:WBGene00013703(gene)|ensemblmetazoa:Y106G6D.7.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-CEL-72163|uniprotkb:Q9U304(identity)|wormbase:WBGene00013703(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:/8MJkmHgCyjvgK0ZmDnklHVfJrw6239 intact-crc:301D1B57255D37B5|rigid:5yh2PPNpjkIVdf7FyfNvBvZG5LA false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q09345 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-2006279|ensemblmetazoa:R144.2a.1|ensemblmetazoa:R144.2a.2 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:pcf11_caeel(display_long)|uniprotkb:R144.2(orf name)|uniprotkb:pcf-11(gene name)|psi-mi:pcf-11(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532244|imex:IM-18681-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_498068.1|wormbase:R144.2a|interpro:IPR008942(ENTH/VHS)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|reactome:R-CEL-6807505|reactome:R-CEL-73856|ensemblmetazoa:R144.2a.1(transcript)|ensemblmetazoa:R144.2a.2(transcript)|ensemblmetazoa:WBGene00020092(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|uniprotkb:Q09345(identity)|wormbase:WBGene00020092(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:XTyRR+k9dN5uoxwUXnAuM34SSUA6239 intact-crc:0D82C8ED8C05DCBC|rigid:rd/9bnSvotxX8DQ45Yb9RJYPSIM false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XTY6 uniprotkb:Q9U2T9 intact:EBI-495781|uniprotkb:Q9BKB5|uniprotkb:Q9XTY4|ensemblmetazoa:T03D8.1a.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:numb1_caeel(display_long)|uniprotkb:Protein kinase C adapter 1(gene name synonym)|uniprotkb:CKA1(gene name synonym)|uniprotkb:num-1(gene name)|psi-mi:num-1(display_short)|uniprotkb:cka-1(gene name synonym)|uniprotkb:T03D8.1(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532259|imex:IM-18681-114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024097.1|refseq:NP_001024098.1|refseq:NP_508021.1|wormbase:T03D8.1a|wormbase:T03D8.1b|wormbase:T03D8.1c|interpro:IPR016698(Numb/numb-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|reactome:R-CEL-437239|reactome:R-CEL-5610780|reactome:R-CEL-5632684|ensemblmetazoa:T03D8.1a.1(transcript)|ensemblmetazoa:WBGene00003830(gene)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0051117"(ATPase binding)|uniprotkb:Q9XTY6(identity)|wormbase:WBGene00003830(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 88|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qO+DFvMBt2DE+ZS7l8axk5DMOFQ6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:FAB6A395D99297F3|rigid:n/cdSAKvhrrEcwawI0/J07caUBM false - sufficient binding region:657-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q4VNJ8 uniprotkb:Q9U2T9 intact:EBI-2918529 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532368|imex:IM-18681-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:F56943DD548D25BD|rigid:lohDnsTbudB7eRV/W8jB30MixYE false - sufficient binding region:657-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:A5PEX6 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-6532321|ensemblmetazoa:Y57A10A.18b.1|ensemblmetazoa:Y57A10A.18b.2 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:a5pex6_caeel(display_long)|uniprotkb:Y57A10A.18(orf name)|uniprotkb:pqn-87(gene name)|psi-mi:pqn-87(display_short)|uniprotkb:CELE_Y57A10A.18(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532323|imex:IM-18681-118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) ensemblmetazoa:WBGene00004167(gene)|ensemblmetazoa:Y57A10A.18b.1(transcript)|ensemblmetazoa:Y57A10A.18b.2(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|refseq:NP_001122665.1|wormbase:Y57A10A.18b|uniprotkb:A5PEX6(identity)|wormbase:WBGene00004167(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:U79ecDJtHc4bqHRcr6eBglpyv5k6239 intact-crc:7A45D1E2D270877B|rigid:4RbwFTLUBrWQhYOdp66os2qG6nM false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U1W1 uniprotkb:Q9U2T9 intact:EBI-315106|ensemblmetazoa:Y63D3A.5.1|ensemblmetazoa:Y63D3A.5.2 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:tfg_caeel(display_long)|uniprotkb:tfg-1(gene name)|psi-mi:tfg-1(display_short)|uniprotkb:Y63D3A.5(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532353|imex:IM-18681-120 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493462.1|wormbase:Y63D3A.5|ensemblmetazoa:WBGene00006565(gene)|ensemblmetazoa:Y63D3A.5.1(transcript)|ensemblmetazoa:Y63D3A.5.2(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009306"(protein secretion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072595"(maintenance of protein localization in organelle)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|dip:DIP-26017N|reactome:R-CEL-204005|uniprotkb:Q9U1W1(identity)|wormbase:WBGene00006565(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:nqyc7+EyDkiVah2+12hsLFWeNdA6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:8E7C3BC284659DB4|rigid:DekU/mDI0dlluCVEKOjMFJKXM7s false - sufficient binding region:657-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q9N4A9 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-324656|ensemblmetazoa:Y77E11A.2.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:q9n4a9_caeel(display_long)|uniprotkb:nadk-1(gene name)|psi-mi:nadk-1(display_short)|uniprotkb:CELE_Y77E11A.2(orf name)|uniprotkb:Y77E11A.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532383|imex:IM-18681-122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_500084.2|wormbase:Y77E11A.2|ensemblmetazoa:WBGene00022307(gene)|ensemblmetazoa:Y77E11A.2.1(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|dip:DIP-24720N|uniprotkb:Q9N4A9(identity)|wormbase:WBGene00022307(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:eKOdyVxVm1LzYJrijR/u4sVqYk86239 intact-crc:89B05413D08995F0|rigid:qIPu9UFWE5ll1Xs/EGDiZZ5L8CI false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:G5ED33 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532338|imex:IM-18681-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:86E3153EB525F7AD|rigid:IbVKO/xQ9SFAuRnV1cg0HydwkcM false sufficient binding region:657-1085 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:P39055 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532443|imex:IM-18681-126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 13|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:2A72157E1EDE4251|rigid:KGIlbaGM1p6K/buAocDcDMtI8Wo false sufficient binding region:274-329 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:G5EDW5 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-2411899|ensemblmetazoa:C04A11.4a.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:g5edw5_caeel(display_long)|uniprotkb:adm-2(gene name)|psi-mi:adm-2(display_short)|uniprotkb:C04A11.4(orf name)|uniprotkb:CELE_C04A11.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532398|imex:IM-18681-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) uniprotkb:O17569(uniprot-removed-ac)|wormbase:C04A11.4a|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR024079|refseq:NP_510291.1|reactome:R-CEL-6798695|interpro:IPR034027|interpro:IPR036436|reactome:R-CEL-1474228|ensemblmetazoa:C04A11.4a.1(transcript)|ensemblmetazoa:WBGene00000074(gene)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|uniprotkb:G5EDW5(identity)|wormbase:WBGene00000074(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:iJQB3mLYJDHdG8uP+O5Uuvcv+SQ6239 intact-crc:E5A9000E6FF36EB8|rigid:fYNSeww2gHL0vcgC6TmBribvpOg false sufficient binding region:194-251 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:O16299 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532413|imex:IM-18681-124 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 130|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 intact-crc:7A10EBBC35F25420|rigid:32JGSdLSKDGh/tKt9mWlGfCxVAs false sufficient binding region:194-251 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:P34552 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-322767|uniprotkb:Q7YXC7|uniprotkb:Q8I114|uniprotkb:Q8I115|uniprotkb:Q94159|ensemblmetazoa:R10E12.1b.1|ensemblmetazoa:R10E12.1b.2 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:alxa_caeel(display_long)|uniprotkb:alx-1(gene name)|psi-mi:alx-1(display_short)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 58"(gene name synonym)|uniprotkb:Protein YNK1(gene name synonym)|uniprotkb:pqn-58(gene name synonym)|uniprotkb:R10E12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532428|imex:IM-18681-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) refseq:NP_001022713.1|refseq:NP_001022714.1|refseq:NP_001022715.1|refseq:NP_499213.1|wormbase:R10E12.1a|wormbase:R10E12.1b|wormbase:R10E12.1c|wormbase:R10E12.1d|interpro:IPR004328(BRO1)|interpro:IPR025304|ensemblmetazoa:R10E12.1b.1(transcript)|ensemblmetazoa:R10E12.1b.2(transcript)|ensemblmetazoa:WBGene00007010(gene)|go:"GO:0005112"(Notch binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0007032"(endosome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043226"(organelle)|go:"GO:0055037"(recycling endosome)|interpro:IPR038499|uniprotkb:P34552(identity)|wormbase:WBGene00007010(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:xedXAHU8Ms6VcKj1w9YZDHURHHg6239 intact-crc:4C6C68F6A2618E0B|rigid:cuLlVAfn3RZQB6JMOeWqviMu348 false sufficient binding region:194-251 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45603 uniprotkb:P34258 intact:EBI-313357|ensemblmetazoa:H02I12.5.1 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 psi-mi:o45603_caeel(display_long)|uniprotkb:memi-3(gene name)|psi-mi:memi-3(display_short)|uniprotkb:CELE_H02I12.5(orf name)|uniprotkb:H02I12.5(orf name) psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532503|imex:IM-18681-130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502151.1|wormbase:H02I12.5|ensemblmetazoa:H02I12.5.1(transcript)|ensemblmetazoa:WBGene00010353(gene)|dip:DIP-26445N|uniprotkb:O45603(identity)|wormbase:WBGene00010353(identity) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:6JI27ecswA6ONqSDNzvGxXYr52Y6239 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 intact-crc:9082EFB27D36951F|rigid:Q0Aq+bbtf8Gbw/5ZpA1qDF9Fgpk false - sufficient binding region:274-329 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:E3W743 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532458|imex:IM-18681-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 29|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 intact-crc:BFDE304F44BE2FD5|rigid:XaRJGbnDT80kU+dvNvvmDjxeUho false sufficient binding region:274-329 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:Q20330 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-322042|ensemblmetazoa:F42C5.10.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:q20330_caeel(display_long)|uniprotkb:ifo-1(gene name)|psi-mi:ifo-1(display_short)|uniprotkb:ttm-4(gene name synonym)|uniprotkb:CELE_F42C5.10(orf name)|uniprotkb:F42C5.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532473|imex:IM-18681-128 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) refseq:NP_501170.1|wormbase:F42C5.10|ensemblmetazoa:F42C5.10.1(transcript)|ensemblmetazoa:WBGene00018350(gene)|dip:DIP-27375N|uniprotkb:Q20330(identity)|wormbase:WBGene00018350(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:G/TdIwuOTGQMqaW/I1aJ4GvrtlU6239 intact-crc:86B21FDD44743229|rigid:mxAe3GOs5U7gQBOl/sPjRXlSxeU false sufficient binding region:274-329 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:Q20745 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-313630|uniprotkb:Q9U475|uniprotkb:Q9U476|ensemblmetazoa:F54B11.3a.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:unc84_caeel(display_long)|uniprotkb:unc-84(gene name)|psi-mi:unc-84(display_short)|uniprotkb:F54B11.3(orf name)|uniprotkb:Uncoordinated protein 84(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532488|imex:IM-18681-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) refseq:NP_001024707.1|refseq:NP_001024708.1|wormbase:F54B11.3a|wormbase:F54B11.3b|interpro:IPR012919(Sad1/UNC-like, C-terminal)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|ensemblmetazoa:F54B11.3a.1(transcript)|ensemblmetazoa:WBGene00006816(gene)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018991"(oviposition)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030473"(nuclear migration along microtubule)|uniprotkb:Q20745(identity)|wormbase:WBGene00006816(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:E2787KAIlfqsfhAVj50VELMPMeU6239 intact-crc:7062C68BCF5FE9B1|rigid:gIzMjYJcygWNXtbbCr/f+L+1D5A false sufficient binding region:274-329 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19246 uniprotkb:P34258 intact:EBI-6532578|ensemblmetazoa:F09E10.3.1 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 psi-mi:q19246_caeel(display_long)|uniprotkb:F09E10.3(orf name)|uniprotkb:dhs-25(gene name)|psi-mi:dhs-25(display_short)|uniprotkb:CELE_F09E10.3(orf name) psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532580|imex:IM-18681-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F09E10.3.1(transcript)|ensemblmetazoa:WBGene00000988(gene)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0048038"(quinone binding)|wormbase:F09E10.3|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|refseq:NP_508282.2|interpro:IPR036291|uniprotkb:Q19246(identity)|wormbase:WBGene00000988(identity) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:/9OXoN4g7Wmomnj4Ui7NHZDn1T86239 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 intact-crc:285CF12258E456AE|rigid:1Bdj7amk/UajKVCm9/pD1ncVs8Y false - sufficient binding region:434-493 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:Q21648 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532563|imex:IM-18681-134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 intact-crc:2D2479884494E1F7|rigid:gOKAyIa6wGAa1JQRaDzcC0GDrd0 false sufficient binding region:358-413 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:Q21648 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532518|imex:IM-18681-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 intact-crc:060B21C1CCA99136|rigid:gOKAyIa6wGAa1JQRaDzcC0GDrd0 false sufficient binding region:274-329 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:Q23356 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-326940|uniprotkb:Q8I4B5|uniprotkb:Q8T8M3|uniprotkb:Q95ZI7|uniprotkb:Q9UAN7|uniprotkb:Q9XYC3|uniprotkb:Q9XYC4|ensemblmetazoa:ZC504.4c.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:mig15_caeel(display_long)|uniprotkb:mig-15(gene name)|psi-mi:mig-15(display_short)|uniprotkb:Abnormal cell migration protein 15(gene name synonym)|uniprotkb:ZC504.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532533|imex:IM-18681-132 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) refseq:NP_001024971.1|refseq:NP_001024972.1|refseq:NP_001024973.1|refseq:NP_001024974.1|wormbase:ZC504.4a|wormbase:ZC504.4b|wormbase:ZC504.4c|wormbase:ZC504.4d|ensemblmetazoa:WBGene00003247(gene)|ensemblmetazoa:ZC504.4c.1(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010171"(body morphogenesis)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0000165"(MAPK cascade)|dip:DIP-25874N|reactome:R-CEL-2559580|uniprotkb:Q23356(identity)|wormbase:WBGene00003247(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 22|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:JAFUfFZU8Ja8JtrvD7VNrXOpZCI6239 intact-crc:C1DAD733F16481E3|rigid:0qo5HCXi82F7Yau8IqojsnJBMik false sufficient binding region:274-329 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:Q19749 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532548|imex:IM-18681-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N|uniprotkb:Q19749(identity)|wormbase:WBGene00009082(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 intact-crc:82AAE4C0BBB6C395|rigid:n5ScYfl/xTZkRnMjH+z6txTMWfo false sufficient binding region:358-413 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:P34400 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-2315872|uniprotkb:P34386|uniprotkb:P34403|uniprotkb:Q7JQ80|uniprotkb:Q8WT53|ensemblmetazoa:F10E9.6c.1|ensemblmetazoa:F10E9.6c.2 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:mig10_caeel(display_long)|uniprotkb:mig-10(gene name)|psi-mi:mig-10(display_short)|uniprotkb:F10E9.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532642|imex:IM-18681-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) refseq:NP_001021248.1|refseq:NP_498821.2|refseq:NP_498822.2|wormbase:F10E9.6a|wormbase:F10E9.6b|wormbase:F10E9.6c|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000159(Ras-association)|interpro:IPR029071|reactome:R-CEL-354192|interpro:IPR039664|interpro:IPR039665|reactome:R-CEL-354194|reactome:R-CEL-5674135|ensemblmetazoa:F10E9.6c.1(transcript)|ensemblmetazoa:F10E9.6c.2(transcript)|ensemblmetazoa:WBGene00003243(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0007165"(signal transduction)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018991"(oviposition)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031941"(filamentous actin)|go:"GO:0032584"(growth cone membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0043204"(perikaryon)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099523"(presynaptic cytosol)|uniprotkb:P34400(identity)|wormbase:WBGene00003243(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:qni0Ph9hE7m4FAxHa2yRYfjO0qY6239 intact-crc:E99BA36FF3F62766|rigid:sGHrRol5Jaj0wKlr/fXcfJO/YEw false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:Q02328 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-6532599|ensemblmetazoa:ZK370.3a.2|ensemblmetazoa:ZK370.3a.1|uniprotkb:Q95PX2 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:slap2_caeel(display_long)|uniprotkb:hipr-1(gene name)|psi-mi:hipr-1(display_short)|uniprotkb:Actin-binding protein SLA2 homolog(gene name synonym)|uniprotkb:ZK370.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532595|imex:IM-18681-136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) ensemblmetazoa:ZK370.3a.2(transcript)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007624"(ultradian rhythm)|go:"GO:0008104"(protein localization)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030421"(defecation)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032502"(developmental process)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098793"(presynapse)|ensemblmetazoa:WBGene00022717(gene)|ensemblmetazoa:ZK370.3a.1(transcript)|interpro:IPR030224|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|refseq:NP_498925.1|refseq:NP_741253.1|wormbase:ZK370.3a|wormbase:ZK370.3b|interpro:IPR035964|reactome:R-CEL-432722|reactome:R-CEL-8856828|uniprotkb:Q02328(identity)|wormbase:WBGene00022717(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:usXHq5sLzi57I/psS1rV+pgbQZI6239 intact-crc:8AC5BB7AA2C338D0|rigid:ckuYggim0NPaGEHSXqH6lFER+wE false sufficient binding region:434-493 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:P34258 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532612|imex:IM-18681-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 intact-crc:FFE38B42FC12B12C|rigid:MHABivgwMsjQC427auI1F65HgYI false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:Q10929 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532627|imex:IM-18681-138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 intact-crc:619A86EE31286936|rigid:HeJ+9ii+YyiWPCBMn75uo3AsaUM false - sufficient binding region:415-469 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:G5ECQ3 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-6532702|ensemblmetazoa:F35G12.3a.1|ensemblmetazoa:F35G12.3a.2|uniprotkb:G5EFY9 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:sel5_caeel(display_long)|uniprotkb:Suppressor/enhancer of lin-12 protein 5(gene name synonym)|uniprotkb:F35G12.3(orf name)|uniprotkb:sel-5(gene name)|psi-mi:sel-5(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532704|imex:IM-18681-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) ensemblmetazoa:F35G12.3a.1(transcript)|ensemblmetazoa:F35G12.3a.2(transcript)|ensemblmetazoa:WBGene00004762(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|wormbase:F35G12.3b|refseq:NP_001022563.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_001022562.1|wormbase:F35G12.3a|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:G5ECQ3(identity)|wormbase:WBGene00004762(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:kVuctoNz+qN024pUQQNNP3RnU2A6239 intact-crc:87A7F7984E6FBB84|rigid:G0CdUsvdocMCu50Vmmd4BnyOT6w false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:Q19905 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532657|imex:IM-18681-140 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N|uniprotkb:Q19905(identity)|wormbase:WBGene00005022(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 intact-crc:B92C39DBE952DDAF|rigid:OgzZDnppp2bBoSsygYDTL0NGo8Q false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:O62203 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-320780|ensemblmetazoa:F32B4.4a.1|intact:EBI-6530763|uniprotkb:F5GUF6|uniprotkb:Q7Z0X2 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:phm2_caeel(display_long)|uniprotkb:phm-2(gene name)|psi-mi:phm-2(display_short)|uniprotkb:F32B4.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532672|imex:IM-18681-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) wormbase:F32B4.4a|ensemblmetazoa:F32B4.4a.1(transcript)|ensemblmetazoa:WBGene00009314(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007586"(digestion)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036361|refseq:NP_001021441.1|refseq:NP_001251667.1|refseq:NP_001021440.2|dip:DIP-25849N|reactome:R-CEL-3899300|wormbase:F32B4.4b|wormbase:F32B4.4c|uniprotkb:F5GUF6(identity)|wormbase:WBGene00009314(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/03/02 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:69Kg/RUbe1gThWpe8yrWyt9o0bQ6239 intact-crc:9DD41E02121F82EA|rigid:wI5oIK6VCsTjdra3yDcAI7kkrIU false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:O16299 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532687|imex:IM-18681-142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 intact-crc:5A9ED7CBDC5F185D|rigid:J33PVMNIPsr3qu+0cytlCz1bhxk false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:H2L045 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-325972|ensemblmetazoa:M01E11.7a.1|intact:EBI-2914896|uniprotkb:A0A0S4XR26|uniprotkb:A0A0S4XR31|uniprotkb:A0A0S4XR51|uniprotkb:A0A0S4XR69|uniprotkb:H2L046|uniprotkb:H2L047|uniprotkb:P92160 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:tensh_caeel(display_long)|uniprotkb:tag-163(gene name synonym)|uniprotkb:tns-1(gene name)|psi-mi:tns-1(display_short)|uniprotkb:M01E11.7(orf name)|uniprotkb:svh-6(gene name synonym)|uniprotkb:C1 domain-containing phosphatase and tensin homolog(gene name synonym)|uniprotkb:Suppressor of vhp-1 deletion lethality protein svh-6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532766|imex:IM-18681-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) uniprotkb:Q95ZL4(uniprot-removed-ac)|wormbase:M01E11.7a|interpro:IPR000980(SH2 motif)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|refseq:NP_001305199.1|refseq:NP_001305202.1|refseq:NP_001305203.1|refseq:NP_001305204.1|ensemblmetazoa:M01E11.7a.1(transcript)|ensemblmetazoa:WBGene00006508(gene)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0030054"(cell junction)|go:"GO:0030424"(axon)|go:"GO:0031430"(M band)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0055120"(striated muscle dense body)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|refseq:NP_491637.2|interpro:IPR033929|interpro:IPR035012|interpro:IPR036860|refseq:NP_491636.1|wormbase:M01E11.7b|wormbase:M01E11.7c|wormbase:M01E11.7d|wormbase:M01E11.7e|wormbase:M01E11.7f|wormbase:M01E11.7g|wormbase:M01E11.7h|refseq:NP_491638.1|refseq:NP_740854.1|interpro:IPR035892|uniprotkb:P92160(identity)|wormbase:WBGene00006508(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/03/02 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:RSgRFHcjsdUjIFspYSZicQHRRA06239 intact-crc:C4D582520BA67958|rigid:F6qVFoRk6+nHlgPYrGZPJMkkm1M false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q966J6 uniprotkb:Q10929 intact:EBI-327612|ensemblmetazoa:F41B4.1.1 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 psi-mi:q966j6_caeel(display_long)|uniprotkb:F41B4.1(orf name)|uniprotkb:CELE_F41B4.1(orf name) psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532719|imex:IM-18681-144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509148.2|wormbase:F41B4.1|ensemblmetazoa:F41B4.1.1(transcript)|ensemblmetazoa:WBGene00018257(gene)|dip:DIP-26336N|uniprotkb:Q966J6(identity)|wormbase:WBGene00018257(identity) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 40|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:daBFAeewQ1vhaxj4tlw0watbWpw6239 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 intact-crc:E3F2A3A9DD40C698|rigid:zBvjz+fr9wsrSljQsPapdNjhKrE false - sufficient binding region:415-469 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:B6VQ68 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-6532738|ensemblmetazoa:F47B10.8b.1 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:b6vq68_caeel(display_long)|uniprotkb:CELE_F47B10.8(orf name)|uniprotkb:F47B10.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532734|imex:IM-18681-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) ensemblmetazoa:F47B10.8b.1(transcript)|ensemblmetazoa:WBGene00009819(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_001257121.1|wormbase:F47B10.8b|uniprotkb:B6VQ68(identity)|wormbase:WBGene00009819(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:u492AiFUjfw+KPWgcXieweG6l5A6239 intact-crc:95EC0D42716E4EB7|rigid:bkaJ8EsuiKdbc8PuFbfYeBqMLQA false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL2 uniprotkb:Q10929 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532751|imex:IM-18681-146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 intact-crc:42040117AC118CB8|rigid:EZ3zel3kAD1x3wmkTgsMZnfiYYc false - sufficient binding region:415-469 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4A9 uniprotkb:G5EBZ8 intact:EBI-324656|ensemblmetazoa:Y77E11A.2.1 intact:EBI-6532845|ensemblmetazoa:C01C7.1a.1|uniprotkb:C6KRP0 psi-mi:q9n4a9_caeel(display_long)|uniprotkb:nadk-1(gene name)|psi-mi:nadk-1(display_short)|uniprotkb:CELE_Y77E11A.2(orf name)|uniprotkb:Y77E11A.2(orf name) psi-mi:ark1_caeel(display_long)|uniprotkb:ark-1(gene name)|psi-mi:ark-1(display_short)|uniprotkb:Ras-regulating kinase ark-1(gene name synonym)|uniprotkb:C01C7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532841|imex:IM-18681-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500084.2|wormbase:Y77E11A.2|ensemblmetazoa:WBGene00022307(gene)|ensemblmetazoa:Y77E11A.2.1(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|dip:DIP-24720N|uniprotkb:Q9N4A9(identity)|wormbase:WBGene00022307(identity) ensemblmetazoa:C01C7.1a.1(transcript)|ensemblmetazoa:WBGene00000186(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_001255653.1|refseq:NP_001255654.1|wormbase:C01C7.1a|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|wormbase:C01C7.1b|interpro:IPR036028|uniprotkb:C6KRP0(identity)|wormbase:WBGene00000186(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/09/24 rogid:eKOdyVxVm1LzYJrijR/u4sVqYk86239 rogid:3y4DKCGtK0UAmuo7wGZIoULkmis6239 intact-crc:3DA747C17824E0A9|rigid:okZeNCFBs8eBL/Y5yUj6FnwjTzU false - sufficient binding region:382-443 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:G5ED33 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532826|imex:IM-18681-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:E64B45BCB25738FE|rigid:A50+82KtX8npklosFvsvrvxZhY4 false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:Q95Y95 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-2315841|ensemblmetazoa:M04F3.5b.1 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:q95y95_caeel(display_long)|uniprotkb:CELE_M04F3.5(orf name)|uniprotkb:M04F3.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532781|imex:IM-18681-148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) refseq:NP_491448.2|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR030127|wormbase:M04F3.5b|ensemblmetazoa:M04F3.5b.1(transcript)|ensemblmetazoa:WBGene00019771(gene)|go:"GO:0003779"(actin binding)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030175"(filopodium)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0061024"(membrane organization)|uniprotkb:Q95Y95(identity)|wormbase:WBGene00019771(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 124|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:bMOvoO4LBVIjnKdrG/YFcgmXUCE6239 intact-crc:DEA41790923FF143|rigid:RqleB4ocXVbZGaDrvqpdVAmrGbI false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91820 uniprotkb:Q10929 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532796|imex:IM-18681-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N|uniprotkb:P91820(identity)|wormbase:WBGene00003083(identity) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 intact-crc:AB969053E4AB5088|rigid:29SiLb+no/qq28TQZZXmberX1uw false - sufficient binding region:415-469 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWN1 uniprotkb:Q10929 intact:EBI-324865|ensemblmetazoa:Y43F8C.6a.1 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 psi-mi:q9xwn1_caeel(display_long)|uniprotkb:Y43F8C.6(orf name)|uniprotkb:CELE_Y43F8C.6(orf name) psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532811|imex:IM-18681-150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256880.1|wormbase:Y43F8C.6a|ensemblmetazoa:WBGene00012828(gene)|ensemblmetazoa:Y43F8C.6a.1(transcript)|go:"GO:0016589"(NURF complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR037931|dip:DIP-27198N|uniprotkb:Q9XWN1(identity)|wormbase:WBGene00012828(identity) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BnRBxnWaRRWRCAx+LGlNwRaOcOU6239 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 intact-crc:AC3B42D4E1B8B551|rigid:Id7Fwd49Cw2/kKbkGp8FuigRcLA false - sufficient binding region:415-469 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01761 uniprotkb:Q9BKP3 intact:EBI-314725|uniprotkb:Q17362|uniprotkb:Q5W614|uniprotkb:Q5W615|uniprotkb:Q5W616|uniprotkb:Q5W617|uniprotkb:Q646H5|uniprotkb:Q64EQ8|uniprotkb:Q7Z119|uniprotkb:Q7Z120|ensemblmetazoa:C09D1.1b.1|ensemblmetazoa:C09D1.1g.1 intact:EBI-6532905|ensemblmetazoa:H19M22.2c.1 psi-mi:unc89_caeel(display_long)|uniprotkb:C09D1.1(orf name)|uniprotkb:Uncoordinated protein 89(gene name synonym)|uniprotkb:unc-89(gene name)|psi-mi:unc-89(display_short)|uniprotkb:Obscurin(gene name synonym)|uniprotkb:Inactive serine/threonine-protein kinase unc-89(gene name synonym) psi-mi:q9bkp3_caeel(display_long)|uniprotkb:H19M22.2(orf name)|uniprotkb:let-805(gene name)|psi-mi:let-805(display_short)|uniprotkb:CELE_H19M22.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532907|imex:IM-18681-156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|refseq:NP_001020984.1|refseq:NP_001020985.1|refseq:NP_001020988.1|refseq:NP_001020989.1|refseq:NP_001020990.1|wormbase:C09D1.1a|wormbase:C09D1.1b|wormbase:C09D1.1c|wormbase:C09D1.1d|wormbase:C09D1.1e|wormbase:C09D1.1f|wormbase:C09D1.1g|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007850(RCSD)|interpro:IPR001452(Src homology-3)|rcsb pdb:1FHO|refseq:NP_001293453.1|refseq:NP_001293454.1|ensemblmetazoa:C09D1.1b.1(transcript)|ensemblmetazoa:C09D1.1g.1(transcript)|ensemblmetazoa:WBGene00006820(gene)|ensemblmetazoa:WBGene00006820(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0014722"(regulation of skeletal muscle contraction by calcium ion signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0090736"(MATH domain binding)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905905"(pharyngeal gland morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR013106(Immunoglobulin V-set)|ensemblmetazoa:WBGene00006820(gene)|uniprotkb:O01761(identity)|wormbase:WBGene00006820(identity) ensemblmetazoa:H19M22.2c.1(transcript)|ensemblmetazoa:WBGene00002915(gene)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0043235"(receptor complex)|refseq:NP_001293642.1|wormbase:H19M22.2c|uniprotkb:Q9BKP3(identity)|wormbase:WBGene00002915(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:84zR3QKMivdFjveSZ43aBEGX/CM6239 rogid:SjkoY4LhauaQpAj37X8Ore+almU6239 intact-crc:1224D85B240CFBF6|rigid:eNcTXS5l+jB1/rT6/wh6XJ/QXKk false sufficient binding region:66-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01960 uniprotkb:O01761 intact:EBI-6532858|ensemblmetazoa:C27A12.3.1 intact:EBI-314725|uniprotkb:Q17362|uniprotkb:Q5W614|uniprotkb:Q5W615|uniprotkb:Q5W616|uniprotkb:Q5W617|uniprotkb:Q646H5|uniprotkb:Q64EQ8|uniprotkb:Q7Z119|uniprotkb:Q7Z120|ensemblmetazoa:C09D1.1b.1|ensemblmetazoa:C09D1.1g.1 psi-mi:o01960_caeel(display_long)|uniprotkb:let-391(gene name)|psi-mi:let-391(display_short)|uniprotkb:tag-146(gene name synonym)|uniprotkb:C27A12.3(orf name)|uniprotkb:CELE_C27A12.3(orf name) psi-mi:unc89_caeel(display_long)|uniprotkb:C09D1.1(orf name)|uniprotkb:Uncoordinated protein 89(gene name synonym)|uniprotkb:unc-89(gene name)|psi-mi:unc-89(display_short)|uniprotkb:Obscurin(gene name synonym)|uniprotkb:Inactive serine/threonine-protein kinase unc-89(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532860|imex:IM-18681-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C27A12.3.1(transcript)|ensemblmetazoa:WBGene00006492(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_491744.3|wormbase:C27A12.3|interpro:IPR036236|uniprotkb:O01960(identity)|wormbase:WBGene00006492(identity) interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|refseq:NP_001020984.1|refseq:NP_001020985.1|refseq:NP_001020988.1|refseq:NP_001020989.1|refseq:NP_001020990.1|wormbase:C09D1.1a|wormbase:C09D1.1b|wormbase:C09D1.1c|wormbase:C09D1.1d|wormbase:C09D1.1e|wormbase:C09D1.1f|wormbase:C09D1.1g|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007850(RCSD)|interpro:IPR001452(Src homology-3)|rcsb pdb:1FHO|refseq:NP_001293453.1|refseq:NP_001293454.1|ensemblmetazoa:C09D1.1b.1(transcript)|ensemblmetazoa:C09D1.1g.1(transcript)|ensemblmetazoa:WBGene00006820(gene)|ensemblmetazoa:WBGene00006820(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0014722"(regulation of skeletal muscle contraction by calcium ion signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0090736"(MATH domain binding)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905905"(pharyngeal gland morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR013106(Immunoglobulin V-set)|ensemblmetazoa:WBGene00006820(gene)|uniprotkb:O01761(identity)|wormbase:WBGene00006820(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 54|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4XW4eoq2smGQYzFRNpCQivWZwkU6239 rogid:84zR3QKMivdFjveSZ43aBEGX/CM6239 intact-crc:C9C13989FB478AAF|rigid:RuSPyTyB8yBH7A5zSTFCaPWL8Dg false - sufficient binding region:66-126 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01761 uniprotkb:Q19749 intact:EBI-314725|uniprotkb:Q17362|uniprotkb:Q5W614|uniprotkb:Q5W615|uniprotkb:Q5W616|uniprotkb:Q5W617|uniprotkb:Q646H5|uniprotkb:Q64EQ8|uniprotkb:Q7Z119|uniprotkb:Q7Z120|ensemblmetazoa:C09D1.1b.1|ensemblmetazoa:C09D1.1g.1 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 psi-mi:unc89_caeel(display_long)|uniprotkb:C09D1.1(orf name)|uniprotkb:Uncoordinated protein 89(gene name synonym)|uniprotkb:unc-89(gene name)|psi-mi:unc-89(display_short)|uniprotkb:Obscurin(gene name synonym)|uniprotkb:Inactive serine/threonine-protein kinase unc-89(gene name synonym) psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532875|imex:IM-18681-154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|refseq:NP_001020984.1|refseq:NP_001020985.1|refseq:NP_001020988.1|refseq:NP_001020989.1|refseq:NP_001020990.1|wormbase:C09D1.1a|wormbase:C09D1.1b|wormbase:C09D1.1c|wormbase:C09D1.1d|wormbase:C09D1.1e|wormbase:C09D1.1f|wormbase:C09D1.1g|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007850(RCSD)|interpro:IPR001452(Src homology-3)|rcsb pdb:1FHO|refseq:NP_001293453.1|refseq:NP_001293454.1|ensemblmetazoa:C09D1.1b.1(transcript)|ensemblmetazoa:C09D1.1g.1(transcript)|ensemblmetazoa:WBGene00006820(gene)|ensemblmetazoa:WBGene00006820(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0014722"(regulation of skeletal muscle contraction by calcium ion signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0090736"(MATH domain binding)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905905"(pharyngeal gland morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR013106(Immunoglobulin V-set)|ensemblmetazoa:WBGene00006820(gene)|uniprotkb:O01761(identity)|wormbase:WBGene00006820(identity) refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N|uniprotkb:Q19749(identity)|wormbase:WBGene00009082(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:84zR3QKMivdFjveSZ43aBEGX/CM6239 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 intact-crc:DCBE6F711F9CD0E9|rigid:usNo3YxMCeI3s1U2onSMo4Mjlo8 false sufficient binding region:66-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49595 uniprotkb:O01761 intact:EBI-1771731|uniprotkb:Q8MNS3|ensemblmetazoa:F42G9.1a.1 intact:EBI-314725|uniprotkb:Q17362|uniprotkb:Q5W614|uniprotkb:Q5W615|uniprotkb:Q5W616|uniprotkb:Q5W617|uniprotkb:Q646H5|uniprotkb:Q64EQ8|uniprotkb:Q7Z119|uniprotkb:Q7Z120|ensemblmetazoa:C09D1.1b.1|ensemblmetazoa:C09D1.1g.1 psi-mi:ppm1g_caeel(display_long)|uniprotkb:ppm-1.G(gene name)|psi-mi:ppm-1.G(display_short)|uniprotkb:Protein phosphatase 2C isoform gamma homolog(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma homolog(gene name synonym)|uniprotkb:F42G9.1(orf name) psi-mi:unc89_caeel(display_long)|uniprotkb:C09D1.1(orf name)|uniprotkb:Uncoordinated protein 89(gene name synonym)|uniprotkb:unc-89(gene name)|psi-mi:unc-89(display_short)|uniprotkb:Obscurin(gene name synonym)|uniprotkb:Inactive serine/threonine-protein kinase unc-89(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532890|imex:IM-18681-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741086.1|wormbase:F42G9.1a|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR015655(Protein phosphatase 2C)|wormbase:F42G9.1b|interpro:IPR036457|refseq:NP_741087.1|ensemblmetazoa:F42G9.1a.1(transcript)|ensemblmetazoa:WBGene00018362(gene)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|uniprotkb:P49595(identity)|wormbase:WBGene00018362(identity) interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|refseq:NP_001020984.1|refseq:NP_001020985.1|refseq:NP_001020988.1|refseq:NP_001020989.1|refseq:NP_001020990.1|wormbase:C09D1.1a|wormbase:C09D1.1b|wormbase:C09D1.1c|wormbase:C09D1.1d|wormbase:C09D1.1e|wormbase:C09D1.1f|wormbase:C09D1.1g|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007850(RCSD)|interpro:IPR001452(Src homology-3)|rcsb pdb:1FHO|refseq:NP_001293453.1|refseq:NP_001293454.1|ensemblmetazoa:C09D1.1b.1(transcript)|ensemblmetazoa:C09D1.1g.1(transcript)|ensemblmetazoa:WBGene00006820(gene)|ensemblmetazoa:WBGene00006820(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0014722"(regulation of skeletal muscle contraction by calcium ion signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0090736"(MATH domain binding)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905905"(pharyngeal gland morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR013106(Immunoglobulin V-set)|ensemblmetazoa:WBGene00006820(gene)|uniprotkb:O01761(identity)|wormbase:WBGene00006820(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:M0woJ8tH2TDR0e6/NYL3F1jMvAE6239 rogid:84zR3QKMivdFjveSZ43aBEGX/CM6239 intact-crc:6329CD830203BDDE|rigid:sVSDp3XfZJ0CwYubybJXsg04a5k false - sufficient binding region:66-126 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29355 uniprotkb:Q65ZB4 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 intact:EBI-6532971|ensemblmetazoa:F54D5.15b.1|ensemblmetazoa:F54D5.15b.2 psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:q65zb4_caeel(display_long)|uniprotkb:CELE_F54D5.15(orf name)|uniprotkb:F54D5.15(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532967|imex:IM-18681-160 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) ensemblmetazoa:F54D5.15b.1(transcript)|ensemblmetazoa:F54D5.15b.2(transcript)|ensemblmetazoa:WBGene00010057(gene)|refseq:NP_001022200.1|wormbase:F54D5.15b|uniprotkb:Q65ZB4(identity)|wormbase:WBGene00010057(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 rogid:HNrF4GLN9SQWi6CrHUP8geHepb06239 intact-crc:617C837CBCE45AD7|rigid:OTheGpc+0IZXjkq+FpGo5/QLf6A false sufficient binding region:157-212 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6BEV5 uniprotkb:O01761 intact:EBI-2002318|intact:EBI-2923757|intact:EBI-2924015|ensemblmetazoa:R06F6.12.1 intact:EBI-314725|uniprotkb:Q17362|uniprotkb:Q5W614|uniprotkb:Q5W615|uniprotkb:Q5W616|uniprotkb:Q5W617|uniprotkb:Q646H5|uniprotkb:Q64EQ8|uniprotkb:Q7Z119|uniprotkb:Q7Z120|ensemblmetazoa:C09D1.1b.1|ensemblmetazoa:C09D1.1g.1 psi-mi:yrmc_caeel(display_long)|uniprotkb:R06F6.12(orf name) psi-mi:unc89_caeel(display_long)|uniprotkb:C09D1.1(orf name)|uniprotkb:Uncoordinated protein 89(gene name synonym)|uniprotkb:unc-89(gene name)|psi-mi:unc-89(display_short)|uniprotkb:Obscurin(gene name synonym)|uniprotkb:Inactive serine/threonine-protein kinase unc-89(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532922|imex:IM-18681-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022277.1|wormbase:R06F6.12|ensemblmetazoa:R06F6.12.1(transcript)|ensemblmetazoa:WBGene00023418(gene)|uniprotkb:Q6BEV5(identity)|wormbase:WBGene00023418(identity) interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|refseq:NP_001020984.1|refseq:NP_001020985.1|refseq:NP_001020988.1|refseq:NP_001020989.1|refseq:NP_001020990.1|wormbase:C09D1.1a|wormbase:C09D1.1b|wormbase:C09D1.1c|wormbase:C09D1.1d|wormbase:C09D1.1e|wormbase:C09D1.1f|wormbase:C09D1.1g|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007850(RCSD)|interpro:IPR001452(Src homology-3)|rcsb pdb:1FHO|refseq:NP_001293453.1|refseq:NP_001293454.1|ensemblmetazoa:C09D1.1b.1(transcript)|ensemblmetazoa:C09D1.1g.1(transcript)|ensemblmetazoa:WBGene00006820(gene)|ensemblmetazoa:WBGene00006820(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0014722"(regulation of skeletal muscle contraction by calcium ion signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0090736"(MATH domain binding)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905905"(pharyngeal gland morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR013106(Immunoglobulin V-set)|ensemblmetazoa:WBGene00006820(gene)|uniprotkb:O01761(identity)|wormbase:WBGene00006820(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:jP7TZCce2muoY78Ruk/qCSELK5M6239 rogid:84zR3QKMivdFjveSZ43aBEGX/CM6239 intact-crc:92A3425FEB74DEB5|rigid:TkrNzQhRTQsU3tPR6XmxfZJNcjo false - sufficient binding region:66-126 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E0R7K7 uniprotkb:O01761 intact:EBI-6457956|ensemblmetazoa:Y59A8B.10b.1 intact:EBI-314725|uniprotkb:Q17362|uniprotkb:Q5W614|uniprotkb:Q5W615|uniprotkb:Q5W616|uniprotkb:Q5W617|uniprotkb:Q646H5|uniprotkb:Q64EQ8|uniprotkb:Q7Z119|uniprotkb:Q7Z120|ensemblmetazoa:C09D1.1b.1|ensemblmetazoa:C09D1.1g.1 psi-mi:e0r7k7_caeel(display_long)|uniprotkb:nova-1(gene name)|psi-mi:nova-1(display_short)|uniprotkb:CELE_Y59A8B.10(orf name)|uniprotkb:Y59A8B.10(orf name) psi-mi:unc89_caeel(display_long)|uniprotkb:C09D1.1(orf name)|uniprotkb:Uncoordinated protein 89(gene name synonym)|uniprotkb:unc-89(gene name)|psi-mi:unc-89(display_short)|uniprotkb:Obscurin(gene name synonym)|uniprotkb:Inactive serine/threonine-protein kinase unc-89(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532937|imex:IM-18681-158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00013347(gene)|ensemblmetazoa:Y59A8B.10b.1(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|refseq:NP_001256770.1|wormbase:Y59A8B.10b|interpro:IPR036612|uniprotkb:E0R7K7(identity)|wormbase:WBGene00013347(identity) interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|refseq:NP_001020984.1|refseq:NP_001020985.1|refseq:NP_001020988.1|refseq:NP_001020989.1|refseq:NP_001020990.1|wormbase:C09D1.1a|wormbase:C09D1.1b|wormbase:C09D1.1c|wormbase:C09D1.1d|wormbase:C09D1.1e|wormbase:C09D1.1f|wormbase:C09D1.1g|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007850(RCSD)|interpro:IPR001452(Src homology-3)|rcsb pdb:1FHO|refseq:NP_001293453.1|refseq:NP_001293454.1|ensemblmetazoa:C09D1.1b.1(transcript)|ensemblmetazoa:C09D1.1g.1(transcript)|ensemblmetazoa:WBGene00006820(gene)|ensemblmetazoa:WBGene00006820(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0014722"(regulation of skeletal muscle contraction by calcium ion signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0090736"(MATH domain binding)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905905"(pharyngeal gland morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR013106(Immunoglobulin V-set)|ensemblmetazoa:WBGene00006820(gene)|uniprotkb:O01761(identity)|wormbase:WBGene00006820(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:QVaBd4MSeHKx8oQFDhK9MhOhdTA6239 rogid:84zR3QKMivdFjveSZ43aBEGX/CM6239 intact-crc:7DF5C1D42E7B1E28|rigid:sHuqYtGu5e0/7dTRp6+tk4EcQaU false - sufficient binding region:66-126 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4A9 uniprotkb:O01761 intact:EBI-324656|ensemblmetazoa:Y77E11A.2.1 intact:EBI-314725|uniprotkb:Q17362|uniprotkb:Q5W614|uniprotkb:Q5W615|uniprotkb:Q5W616|uniprotkb:Q5W617|uniprotkb:Q646H5|uniprotkb:Q64EQ8|uniprotkb:Q7Z119|uniprotkb:Q7Z120|ensemblmetazoa:C09D1.1b.1|ensemblmetazoa:C09D1.1g.1 psi-mi:q9n4a9_caeel(display_long)|uniprotkb:nadk-1(gene name)|psi-mi:nadk-1(display_short)|uniprotkb:CELE_Y77E11A.2(orf name)|uniprotkb:Y77E11A.2(orf name) psi-mi:unc89_caeel(display_long)|uniprotkb:C09D1.1(orf name)|uniprotkb:Uncoordinated protein 89(gene name synonym)|uniprotkb:unc-89(gene name)|psi-mi:unc-89(display_short)|uniprotkb:Obscurin(gene name synonym)|uniprotkb:Inactive serine/threonine-protein kinase unc-89(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532952|imex:IM-18681-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500084.2|wormbase:Y77E11A.2|ensemblmetazoa:WBGene00022307(gene)|ensemblmetazoa:Y77E11A.2.1(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|dip:DIP-24720N|uniprotkb:Q9N4A9(identity)|wormbase:WBGene00022307(identity) interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|refseq:NP_001020984.1|refseq:NP_001020985.1|refseq:NP_001020988.1|refseq:NP_001020989.1|refseq:NP_001020990.1|wormbase:C09D1.1a|wormbase:C09D1.1b|wormbase:C09D1.1c|wormbase:C09D1.1d|wormbase:C09D1.1e|wormbase:C09D1.1f|wormbase:C09D1.1g|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007850(RCSD)|interpro:IPR001452(Src homology-3)|rcsb pdb:1FHO|refseq:NP_001293453.1|refseq:NP_001293454.1|ensemblmetazoa:C09D1.1b.1(transcript)|ensemblmetazoa:C09D1.1g.1(transcript)|ensemblmetazoa:WBGene00006820(gene)|ensemblmetazoa:WBGene00006820(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0014722"(regulation of skeletal muscle contraction by calcium ion signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0090736"(MATH domain binding)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905905"(pharyngeal gland morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR013106(Immunoglobulin V-set)|ensemblmetazoa:WBGene00006820(gene)|uniprotkb:O01761(identity)|wormbase:WBGene00006820(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eKOdyVxVm1LzYJrijR/u4sVqYk86239 rogid:84zR3QKMivdFjveSZ43aBEGX/CM6239 intact-crc:02B788DD51313A5A|rigid:zAB7wX5qwHEN9nZzD9yns2vlDbY false - sufficient binding region:66-126 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29355 uniprotkb:P34559 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 intact:EBI-329772|ensemblmetazoa:T05G5.6.1|ensemblmetazoa:T05G5.6.2 psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:echm_caeel(display_long)|uniprotkb:T05G5.6(orf name)|uniprotkb:ech-6(gene name)|psi-mi:ech-6(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533014|imex:IM-18681-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) reactome:R-CEL-70895|refseq:NP_499156.1|wormbase:T05G5.6|reactome:R-CEL-77310|dip:DIP-26850N|ensemblmetazoa:T05G5.6.1(transcript)|ensemblmetazoa:T05G5.6.2(transcript)|ensemblmetazoa:WBGene00001155(gene)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|reactome:R-CEL-77346|reactome:R-CEL-77348|reactome:R-CEL-77350|reactome:R-CEL-77352|uniprotkb:P34559(identity)|wormbase:WBGene00001155(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 rogid:YI9W2EHH9wnNijR35cIE3uWkI3E6239 intact-crc:8420F3056E03FE69|rigid:kKyO+qYaIQQ2vyCKdEzmLOrjdJI false sufficient binding region:157-212 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BKP3 uniprotkb:P29355 intact:EBI-6532905|ensemblmetazoa:H19M22.2c.1 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 psi-mi:q9bkp3_caeel(display_long)|uniprotkb:H19M22.2(orf name)|uniprotkb:let-805(gene name)|psi-mi:let-805(display_short)|uniprotkb:CELE_H19M22.2(orf name) psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532984|imex:IM-18681-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:H19M22.2c.1(transcript)|ensemblmetazoa:WBGene00002915(gene)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0043235"(receptor complex)|refseq:NP_001293642.1|wormbase:H19M22.2c|uniprotkb:Q9BKP3(identity)|wormbase:WBGene00002915(identity) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:SjkoY4LhauaQpAj37X8Ore+almU6239 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 intact-crc:709D697F1B72AD58|rigid:z4dzzlGQK1ICBUD+6JVzVYw4nCY false - sufficient binding region:157-212 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29355 uniprotkb:P34552 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 intact:EBI-322767|uniprotkb:Q7YXC7|uniprotkb:Q8I114|uniprotkb:Q8I115|uniprotkb:Q94159|ensemblmetazoa:R10E12.1b.1|ensemblmetazoa:R10E12.1b.2 psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:alxa_caeel(display_long)|uniprotkb:alx-1(gene name)|psi-mi:alx-1(display_short)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 58"(gene name synonym)|uniprotkb:Protein YNK1(gene name synonym)|uniprotkb:pqn-58(gene name synonym)|uniprotkb:R10E12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6532999|imex:IM-18681-162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) refseq:NP_001022713.1|refseq:NP_001022714.1|refseq:NP_001022715.1|refseq:NP_499213.1|wormbase:R10E12.1a|wormbase:R10E12.1b|wormbase:R10E12.1c|wormbase:R10E12.1d|interpro:IPR004328(BRO1)|interpro:IPR025304|ensemblmetazoa:R10E12.1b.1(transcript)|ensemblmetazoa:R10E12.1b.2(transcript)|ensemblmetazoa:WBGene00007010(gene)|go:"GO:0005112"(Notch binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0007032"(endosome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043226"(organelle)|go:"GO:0055037"(recycling endosome)|interpro:IPR038499|uniprotkb:P34552(identity)|wormbase:WBGene00007010(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 rogid:xedXAHU8Ms6VcKj1w9YZDHURHHg6239 intact-crc:A6EA00844039E829|rigid:xR+WKS7soXFukKHV+McsRmpggtI false sufficient binding region:157-212 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29355 uniprotkb:P34708 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 intact:EBI-367204|uniprotkb:Q95Q22|uniprotkb:Q9U2C0|ensemblmetazoa:Y47D3A.6a.1 psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:tra1_caeel(display_long)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533078|imex:IM-18681-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) wormbase:Y47D3A.6a|wormbase:Y47D3A.6b|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008406"(gonad development)|go:"GO:0019099"(female germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0019101"(female somatic sex determination)|interpro:IPR036236|uniprotkb:P34708(identity)|wormbase:WBGene00006604(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239 intact-crc:16BC8145C21E3096|rigid:SeFFF82k5Gwl18TVTskh5oefhZI false sufficient binding region:157-212 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29355 uniprotkb:A7DT37 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 intact:EBI-6533029|ensemblmetazoa:T06D4.1b.1|ensemblmetazoa:T06D4.1b.2|ensemblmetazoa:T06D4.1b.3 psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:a7dt37_caeel(display_long)|uniprotkb:CELE_T06D4.1(orf name)|uniprotkb:T06D4.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533031|imex:IM-18681-164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) ensemblmetazoa:T06D4.1b.1(transcript)|ensemblmetazoa:T06D4.1b.2(transcript)|ensemblmetazoa:T06D4.1b.3(transcript)|ensemblmetazoa:WBGene00020290(gene)|refseq:NP_001122633.1|wormbase:T06D4.1b|uniprotkb:A7DT37(identity)|wormbase:WBGene00020290(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 rogid:mndl4HVZH7alOmV1/dUcYbG+f1o6239 intact-crc:CBB1C97FFC20AFEA|rigid:fdw+UHkZwV0/8qrWBTRF6ZVo88I false sufficient binding region:157-212 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N5D3 uniprotkb:P29355 intact:EBI-315377|uniprotkb:Q9NBD3|ensemblmetazoa:T28F12.3.1 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 psi-mi:sos_caeel(display_long)|uniprotkb:sos-1(gene name)|psi-mi:sos-1(display_short)|uniprotkb:Guanine nucleotide exchange factor for RAS(gene name synonym)|uniprotkb:let-341(gene name synonym)|uniprotkb:T28F12.3(orf name) psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533046|imex:IM-18681-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504235.2|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR009072(Histone-fold)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR023578|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-186763|reactome:R-CEL-354194|reactome:R-CEL-9013149|reactome:R-CEL-9607240|wormbase:T28F12.3a|ensemblmetazoa:T28F12.3.1(transcript)|ensemblmetazoa:WBGene00004947(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007292"(female gamete generation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016477"(cell migration)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR035899|interpro:IPR036964|reactome:R-CEL-179812|reactome:R-CEL-193648|reactome:R-CEL-1963640|reactome:R-CEL-2179392|reactome:R-CEL-375165|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5673001|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-416482|uniprotkb:Q9N5D3(identity)|wormbase:WBGene00004947(identity) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:oK9Np48YGS1YCmBVWJNZ5NM2osA6239 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 intact-crc:8229B15A77BE2B12|rigid:xkyQ4hodGSPq4NvaqxK9ztqdigI false - sufficient binding region:157-212 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17350 uniprotkb:P29355 intact:EBI-6533065 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 psi-mi:q17350_caeel(display_long) psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533061|imex:IM-18681-166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|uniprotkb:Q17350(identity)|wormbase:WBGene00003902(identity) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:WMhX/u/7thd5HOTeDmBBv136pPY6239 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 intact-crc:786E22EC54AA4289|rigid:MbyHbZufR5DonQ2l3JIsTS3v7Js false - sufficient binding region:157-212 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECY0 uniprotkb:O01961 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 intact:EBI-318544|ensemblmetazoa:C27A12.2.1 psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:o01961_caeel(display_long)|uniprotkb:szy-5(gene name)|psi-mi:szy-5(display_short)|uniprotkb:C27A12.2(orf name)|uniprotkb:CELE_C27A12.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533140|imex:IM-18681-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b|uniprotkb:G5ECY0(identity)|wormbase:WBGene00001006(identity) wormbase:C27A12.2|refseq:NP_491745.2|ensemblmetazoa:C27A12.2.1(transcript)|ensemblmetazoa:WBGene00016154(gene)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|dip:DIP-25195N|uniprotkb:O01961(identity)|wormbase:WBGene00016154(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 rogid:oKG7rQp8lRBUClrjoe9v3IshZ0w6239 intact-crc:DCBC10DF11CB68C5|rigid:DRxjrF6SbMw+hzOa1Q40LcjtyaU false sufficient binding region:622-689 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29355 uniprotkb:E0R7K7 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 intact:EBI-6457956|ensemblmetazoa:Y59A8B.10b.1 psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:e0r7k7_caeel(display_long)|uniprotkb:nova-1(gene name)|psi-mi:nova-1(display_short)|uniprotkb:CELE_Y59A8B.10(orf name)|uniprotkb:Y59A8B.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533093|imex:IM-18681-168 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) ensemblmetazoa:WBGene00013347(gene)|ensemblmetazoa:Y59A8B.10b.1(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|refseq:NP_001256770.1|wormbase:Y59A8B.10b|interpro:IPR036612|uniprotkb:E0R7K7(identity)|wormbase:WBGene00013347(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 58|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 rogid:QVaBd4MSeHKx8oQFDhK9MhOhdTA6239 intact-crc:AA1AE315BBB39639|rigid:u22iFo29znQSAx3OEw24iYOQooo false sufficient binding region:157-212 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29355 uniprotkb:Q9N4A9 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 intact:EBI-324656|ensemblmetazoa:Y77E11A.2.1 psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:q9n4a9_caeel(display_long)|uniprotkb:nadk-1(gene name)|psi-mi:nadk-1(display_short)|uniprotkb:CELE_Y77E11A.2(orf name)|uniprotkb:Y77E11A.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533108|imex:IM-18681-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) refseq:NP_500084.2|wormbase:Y77E11A.2|ensemblmetazoa:WBGene00022307(gene)|ensemblmetazoa:Y77E11A.2.1(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|dip:DIP-24720N|uniprotkb:Q9N4A9(identity)|wormbase:WBGene00022307(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 rogid:eKOdyVxVm1LzYJrijR/u4sVqYk86239 intact-crc:C2937C951C9BEE8B|rigid:6BRrBJkVb9JxdFSic2p+VMo3qPA false sufficient binding region:157-212 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBP4 uniprotkb:P29355 intact:EBI-6533123|ensemblmetazoa:ZK270.2e.1 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 psi-mi:g5ebp4_caeel(display_long)|uniprotkb:ZK270.2(orf name)|uniprotkb:frm-1(gene name)|psi-mi:frm-1(display_short)|uniprotkb:CELE_ZK270.2(orf name) psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533125|imex:IM-18681-170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00001488(gene)|ensemblmetazoa:ZK270.2e.1(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0031032"(actomyosin structure organization)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|refseq:NP_001021866.1|wormbase:ZK270.2e|interpro:IPR029071|interpro:IPR035963|uniprotkb:G5EBP4(identity)|wormbase:WBGene00001488(identity) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 20|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:icCNtsa9axw3hWuvhmT4WH+2pAQ6239 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 intact-crc:55EC2CB90310E6B0|rigid:oOLaWkFmATG5KBQvoDwWd2TEAjM false - sufficient binding region:157-212 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E0R7K7 uniprotkb:Q18204 intact:EBI-6457956|ensemblmetazoa:Y59A8B.10b.1 intact:EBI-6533174|ensemblmetazoa:C26C6.8.1 psi-mi:e0r7k7_caeel(display_long)|uniprotkb:nova-1(gene name)|psi-mi:nova-1(display_short)|uniprotkb:CELE_Y59A8B.10(orf name)|uniprotkb:Y59A8B.10(orf name) psi-mi:q18204_caeel(display_long)|uniprotkb:CELE_C26C6.8(orf name)|uniprotkb:C26C6.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533202|imex:IM-18681-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00013347(gene)|ensemblmetazoa:Y59A8B.10b.1(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|refseq:NP_001256770.1|wormbase:Y59A8B.10b|interpro:IPR036612|uniprotkb:E0R7K7(identity)|wormbase:WBGene00013347(identity) ensemblmetazoa:C26C6.8.1(transcript)|ensemblmetazoa:WBGene00007742(gene)|interpro:IPR001452(Src homology-3)|wormbase:C26C6.8|interpro:IPR036028|refseq:NP_492105.3|uniprotkb:Q18204(identity)|wormbase:WBGene00007742(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/01/08 rogid:QVaBd4MSeHKx8oQFDhK9MhOhdTA6239 rogid:IPbqqIA5kvCzWAWePaVprEo4Hpw6239 intact-crc:F550D640EC636188|rigid:g+p/olnWOAXN2bArLzR1haOjuWc false - sufficient binding region:138-194 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECY0 uniprotkb:Q9GYG1 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 intact:EBI-314846|ensemblmetazoa:ZC395.8.1 psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:q9gyg1_caeel(display_long)|uniprotkb:ztf-8(gene name)|psi-mi:ztf-8(display_short)|uniprotkb:CELE_ZC395.8(orf name)|uniprotkb:ZC395.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533155|imex:IM-18681-172 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b|uniprotkb:G5ECY0(identity)|wormbase:WBGene00001006(identity) refseq:NP_498124.2|wormbase:ZC395.8|ensemblmetazoa:WBGene00022598(gene)|ensemblmetazoa:ZC395.8.1(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|dip:DIP-24679N|uniprotkb:Q9GYG1(identity)|wormbase:WBGene00022598(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 41|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 rogid:wsZC5q+nCfg+Qz99e0wmwQZxK4A6239 intact-crc:624805FB4A13E88A|rigid:VHdexSHQ24Jn9EV3fkst9rorqk0 false sufficient binding region:622-689 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65ZB4 uniprotkb:Q18204 intact:EBI-6532971|ensemblmetazoa:F54D5.15b.1|ensemblmetazoa:F54D5.15b.2 intact:EBI-6533174|ensemblmetazoa:C26C6.8.1 psi-mi:q65zb4_caeel(display_long)|uniprotkb:CELE_F54D5.15(orf name)|uniprotkb:F54D5.15(orf name) psi-mi:q18204_caeel(display_long)|uniprotkb:CELE_C26C6.8(orf name)|uniprotkb:C26C6.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533170|imex:IM-18681-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F54D5.15b.1(transcript)|ensemblmetazoa:F54D5.15b.2(transcript)|ensemblmetazoa:WBGene00010057(gene)|refseq:NP_001022200.1|wormbase:F54D5.15b|uniprotkb:Q65ZB4(identity)|wormbase:WBGene00010057(identity) ensemblmetazoa:C26C6.8.1(transcript)|ensemblmetazoa:WBGene00007742(gene)|interpro:IPR001452(Src homology-3)|wormbase:C26C6.8|interpro:IPR036028|refseq:NP_492105.3|uniprotkb:Q18204(identity)|wormbase:WBGene00007742(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/01/08 rogid:HNrF4GLN9SQWi6CrHUP8geHepb06239 rogid:IPbqqIA5kvCzWAWePaVprEo4Hpw6239 intact-crc:2A1067E37A86591A|rigid:/gSyktEytVksKuCAjxwNNsKDLRk false - sufficient binding region:138-194 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34552 uniprotkb:Q18204 intact:EBI-322767|uniprotkb:Q7YXC7|uniprotkb:Q8I114|uniprotkb:Q8I115|uniprotkb:Q94159|ensemblmetazoa:R10E12.1b.1|ensemblmetazoa:R10E12.1b.2 intact:EBI-6533174|ensemblmetazoa:C26C6.8.1 psi-mi:alxa_caeel(display_long)|uniprotkb:alx-1(gene name)|psi-mi:alx-1(display_short)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 58"(gene name synonym)|uniprotkb:Protein YNK1(gene name synonym)|uniprotkb:pqn-58(gene name synonym)|uniprotkb:R10E12.1(orf name) psi-mi:q18204_caeel(display_long)|uniprotkb:CELE_C26C6.8(orf name)|uniprotkb:C26C6.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533187|imex:IM-18681-174 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022713.1|refseq:NP_001022714.1|refseq:NP_001022715.1|refseq:NP_499213.1|wormbase:R10E12.1a|wormbase:R10E12.1b|wormbase:R10E12.1c|wormbase:R10E12.1d|interpro:IPR004328(BRO1)|interpro:IPR025304|ensemblmetazoa:R10E12.1b.1(transcript)|ensemblmetazoa:R10E12.1b.2(transcript)|ensemblmetazoa:WBGene00007010(gene)|go:"GO:0005112"(Notch binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0007032"(endosome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043226"(organelle)|go:"GO:0055037"(recycling endosome)|interpro:IPR038499|uniprotkb:P34552(identity)|wormbase:WBGene00007010(identity) ensemblmetazoa:C26C6.8.1(transcript)|ensemblmetazoa:WBGene00007742(gene)|interpro:IPR001452(Src homology-3)|wormbase:C26C6.8|interpro:IPR036028|refseq:NP_492105.3|uniprotkb:Q18204(identity)|wormbase:WBGene00007742(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/01/08 rogid:xedXAHU8Ms6VcKj1w9YZDHURHHg6239 rogid:IPbqqIA5kvCzWAWePaVprEo4Hpw6239 intact-crc:382BB58866D2721A|rigid:3V5fTUFBwfW07sI6St2qWvtFOP0 false - sufficient binding region:138-194 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17796 uniprotkb:O01498 intact:EBI-319625|ensemblmetazoa:C07G1.5.1|ensemblmetazoa:C07G1.5.2 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 psi-mi:q17796_caeel(display_long)|uniprotkb:hgrs-1(gene name)|psi-mi:hgrs-1(display_short)|uniprotkb:CELE_C07G1.5(orf name)|uniprotkb:C07G1.5(orf name) psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533262|imex:IM-18681-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501375.2|wormbase:C07G1.5|interpro:IPR024641|ensemblmetazoa:C07G1.5.1(transcript)|ensemblmetazoa:C07G1.5.2(transcript)|ensemblmetazoa:WBGene00004101(gene)|go:"GO:0005769"(early endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|reactome:R-CEL-182971|reactome:R-CEL-432720|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|reactome:R-CEL-6807004|dip:DIP-24324N|reactome:R-CEL-9013420|reactome:R-CEL-9706019|uniprotkb:Q17796(identity)|wormbase:WBGene00004101(identity) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Vt+AmRCoka4jybu2GN4eRvLo+6U6239 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 intact-crc:7CC4633F05322BC5|rigid:957Ha2g0b2jwOZ/KBlXP2p+JW6Q false - sufficient binding region:222-277 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4A9 uniprotkb:Q18204 intact:EBI-324656|ensemblmetazoa:Y77E11A.2.1 intact:EBI-6533174|ensemblmetazoa:C26C6.8.1 psi-mi:q9n4a9_caeel(display_long)|uniprotkb:nadk-1(gene name)|psi-mi:nadk-1(display_short)|uniprotkb:CELE_Y77E11A.2(orf name)|uniprotkb:Y77E11A.2(orf name) psi-mi:q18204_caeel(display_long)|uniprotkb:CELE_C26C6.8(orf name)|uniprotkb:C26C6.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533217|imex:IM-18681-176 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500084.2|wormbase:Y77E11A.2|ensemblmetazoa:WBGene00022307(gene)|ensemblmetazoa:Y77E11A.2.1(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|dip:DIP-24720N|uniprotkb:Q9N4A9(identity)|wormbase:WBGene00022307(identity) ensemblmetazoa:C26C6.8.1(transcript)|ensemblmetazoa:WBGene00007742(gene)|interpro:IPR001452(Src homology-3)|wormbase:C26C6.8|interpro:IPR036028|refseq:NP_492105.3|uniprotkb:Q18204(identity)|wormbase:WBGene00007742(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/01/08 rogid:eKOdyVxVm1LzYJrijR/u4sVqYk86239 rogid:IPbqqIA5kvCzWAWePaVprEo4Hpw6239 intact-crc:B987504A4B9E2723|rigid:QxuRv4utl9FOOJAxg1MG26X4NGE false - sufficient binding region:138-194 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBP4 uniprotkb:Q18204 intact:EBI-6533123|ensemblmetazoa:ZK270.2e.1 intact:EBI-6533174|ensemblmetazoa:C26C6.8.1 psi-mi:g5ebp4_caeel(display_long)|uniprotkb:ZK270.2(orf name)|uniprotkb:frm-1(gene name)|psi-mi:frm-1(display_short)|uniprotkb:CELE_ZK270.2(orf name) psi-mi:q18204_caeel(display_long)|uniprotkb:CELE_C26C6.8(orf name)|uniprotkb:C26C6.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533232|imex:IM-18681-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00001488(gene)|ensemblmetazoa:ZK270.2e.1(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0031032"(actomyosin structure organization)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|refseq:NP_001021866.1|wormbase:ZK270.2e|interpro:IPR029071|interpro:IPR035963|uniprotkb:G5EBP4(identity)|wormbase:WBGene00001488(identity) ensemblmetazoa:C26C6.8.1(transcript)|ensemblmetazoa:WBGene00007742(gene)|interpro:IPR001452(Src homology-3)|wormbase:C26C6.8|interpro:IPR036028|refseq:NP_492105.3|uniprotkb:Q18204(identity)|wormbase:WBGene00007742(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/01/08 rogid:icCNtsa9axw3hWuvhmT4WH+2pAQ6239 rogid:IPbqqIA5kvCzWAWePaVprEo4Hpw6239 intact-crc:367965AAE76EE23A|rigid:2meHFc1QwUfC8GneudUqRBTgvxU false - sufficient binding region:138-194 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01498 uniprotkb:P91001 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 intact:EBI-313007|ensemblmetazoa:B0547.1.1 psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533247|imex:IM-18681-178 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394|uniprotkb:P91001(identity)|wormbase:WBGene00000817(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 intact-crc:DD152218F368AE15|rigid:C8i7czIQ63PpTYEbxB8M+C+nAxE false sufficient binding region:222-277 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20950 uniprotkb:O01498 intact:EBI-312868|ensemblmetazoa:F57F5.1.1 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 psi-mi:q20950_caeel(display_long)|uniprotkb:cpr-9(gene name)|psi-mi:cpr-9(display_short)|uniprotkb:CELE_F57F5.1(orf name)|uniprotkb:F57F5.1(orf name) psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533307|imex:IM-18681-182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506011.2|wormbase:F57F5.1|ensemblmetazoa:F57F5.1.1(transcript)|ensemblmetazoa:WBGene00010204(gene)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|dip:DIP-24447N|uniprotkb:Q20950(identity)|wormbase:WBGene00010204(identity) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:8sXE02/TDt7bidRsEagvVGJS3eE6239 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 intact-crc:6F6477C2ABE6DEDE|rigid:UkLO9Py9huNuUsqu0ZVCXsxv+y0 false - sufficient binding region:222-277 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVE1 uniprotkb:O01498 intact:EBI-2413096|ensemblmetazoa:C14A6.1.1 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 psi-mi:q9xve1_caeel(display_long)|uniprotkb:clec-48(gene name)|psi-mi:clec-48(display_short)|uniprotkb:CELE_C14A6.1(orf name)|uniprotkb:C14A6.1(orf name) psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533277|imex:IM-18681-180 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_507547.1|wormbase:C14A6.1|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|ensemblmetazoa:C14A6.1.1(transcript)|ensemblmetazoa:WBGene00007565(gene)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0038023"(signaling receptor activity)|uniprotkb:Q9XVE1(identity)|wormbase:WBGene00007565(identity) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:SY8RTP6AUv2xVyF7IKlFE4kLvEw6239 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 intact-crc:D4DEE21F1F3F2C8E|rigid:9jd7uI99Zx5sFtxk4ItI7aNlZmA false - sufficient binding region:222-277 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19905 uniprotkb:O01498 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533292|imex:IM-18681-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N|uniprotkb:Q19905(identity)|wormbase:WBGene00005022(identity) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 intact-crc:79988E438EC5D23F|rigid:lme2kVH+DZHeGSQZSi4pTR5vEGQ false - sufficient binding region:222-277 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6533373 uniprotkb:O01498 - intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 psi-mi:g3mu69_caeel(display_short)|psi-mi:EBI-6533373(display_long)|uniprotkb:T27E9.1(orf name)|uniprotkb:ant-1.1(gene name)|psi-mi:ant-1.1(display_short)|uniprotkb:CELE_T27E9.1(orf name) psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533369|imex:IM-18681-186 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:G3MU69(uniprot-removed-ac)|uniprotkb:G3MU69(identity)|wormbase:WBGene00006439(identity) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:haVkJWSnhAa5irdfMD7lj2O3KY46239 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 intact-crc:F77F9FD77BE2E947|rigid:4qRzWbSUe7iGUoH/mpBd82/dwZA false - sufficient binding region:222-277 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01498 uniprotkb:O44624 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 intact:EBI-325383|ensemblmetazoa:K11D12.9.1 psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:o44624_caeel(display_long)|uniprotkb:exc-14(gene name)|psi-mi:exc-14(display_short)|uniprotkb:CELE_K11D12.9(orf name)|uniprotkb:K11D12.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533322|imex:IM-18681-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) refseq:NP_504354.1|wormbase:K11D12.9|ensemblmetazoa:K11D12.9.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|ensemblmetazoa:WBGene00019649(gene)|dip:DIP-26254N|uniprotkb:O44624(identity)|wormbase:WBGene00019649(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 rogid:rvFCmUxObeE9SRUnQ1Ko+x/iUeo6239 intact-crc:F90A62A7A1104EEF|rigid:L8rBFTleicyq+zmuuMMu4q9VU/0 false sufficient binding region:222-277 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01498 uniprotkb:B2D6P5 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 intact:EBI-2919829|ensemblmetazoa:M04G12.1c.1|ensemblmetazoa:M04G12.1c.2 psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:b2d6p5_caeel(display_long)|uniprotkb:tag-260(gene name)|psi-mi:tag-260(display_short)|uniprotkb:ifbp-1(gene name synonym)|uniprotkb:CELE_M04G12.1(orf name)|uniprotkb:M04G12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533337|imex:IM-18681-184 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) ensemblmetazoa:M04G12.1c.1(transcript)|ensemblmetazoa:M04G12.1c.2(transcript)|ensemblmetazoa:WBGene00010867(gene)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR022750|refseq:NP_001122980.1|wormbase:M04G12.1c|interpro:IPR044882|uniprotkb:B2D6P5(identity)|wormbase:WBGene00010867(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 rogid:MBUav8DZj3WeqUqpxjtet5cli/w6239 intact-crc:CA8013F5ADF5CE42|rigid:NAHcpl5uue2sKZyQYca40CWWOLY false sufficient binding region:222-277 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22648 uniprotkb:O01498 intact:EBI-6533352|ensemblmetazoa:T21C9.13.1 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 psi-mi:q22648_caeel(display_long)|uniprotkb:CELE_T21C9.13(orf name)|uniprotkb:T21C9.13(orf name) psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533354|imex:IM-18681-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T21C9.13.1(transcript)|ensemblmetazoa:WBGene00011898(gene)|go:"GO:0016021"(integral component of membrane)|refseq:NP_505721.2|wormbase:T21C9.13|uniprotkb:Q22648(identity)|wormbase:WBGene00011898(identity) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:hg6jtCPI/8OHvlzuEnD7hdEK1Y86239 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 intact-crc:55729E4456CF2128|rigid:pQOpkGMcth0Xts2Eh7g8ND5LrC4 false - sufficient binding region:222-277 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:A0A1C3NSL9 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-327553|ensemblmetazoa:C25A11.4k.1|intact:EBI-11468732|uniprotkb:A0A1C3NSK1|uniprotkb:A0A1C3NSK9|uniprotkb:A0A1C3NSL1|uniprotkb:A0A1C3NSL6|uniprotkb:A0A1C3NSM8|uniprotkb:A0A1C3NSP2|uniprotkb:A0A1C3NSQ2|uniprotkb:G4RTG4|uniprotkb:H2KYC4|uniprotkb:H2KYC6 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:ajm1_caeel(display_long)|uniprotkb:ajm-1(gene name)|psi-mi:ajm-1(display_short)|uniprotkb:CELE_C25A11.4(orf name)|uniprotkb:C25A11.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533416|imex:IM-18681-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) uniprotkb:Q18138(uniprot-removed-ac)|interpro:IPR038825|wormbase:C25A11.4e|interpro:IPR002893(Zinc finger, MYND-type)|ensemblmetazoa:C25A11.4k.1(transcript)|ensemblmetazoa:WBGene00000100(gene)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044292"(dendrite terminus)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046872"(metal ion binding)|refseq:NP_001317735.1|refseq:NP_001317736.1|refseq:NP_001317888.1|refseq:NP_001317890.1|refseq:NP_001317891.1|refseq:NP_001317897.1|refseq:NP_001317898.1|refseq:NP_001317899.1|refseq:NP_509536.1|refseq:NP_001317887.1|refseq:NP_001317889.1|wormbase:C25A11.4a|wormbase:C25A11.4d|wormbase:C25A11.4f|wormbase:C25A11.4g|wormbase:C25A11.4h|wormbase:C25A11.4i|wormbase:C25A11.4j|wormbase:C25A11.4k|wormbase:C25A11.4l|wormbase:C25A11.4m|uniprotkb:G4RTG4(identity)|wormbase:WBGene00000100(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/26 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:r7BJygBJ3u4aJy/4+mWnsMDUgLo6239 intact-crc:8B3E306BC3F35E90|rigid:HDZ/ipIiA+W3+CoKb/wpfOwdwhg false sufficient binding region:857-918 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XQ1 uniprotkb:O01498 intact:EBI-313459|ensemblmetazoa:Y39G10AR.17.1 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 psi-mi:sydn_caeel(display_long)|uniprotkb:Y39G10AR.17(orf name)|uniprotkb:sydn-1(gene name)|psi-mi:sydn-1(display_short) psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533386|imex:IM-18681-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y39G10AR.17|ensemblmetazoa:WBGene00021473(gene)|ensemblmetazoa:Y39G10AR.17.1(transcript)|go:"GO:0016607"(nuclear speck)|go:"GO:0006397"(mRNA processing)|mint:Q95XQ1|refseq:NP_490969.4|dip:DIP-24383N|uniprotkb:Q95XQ1(identity)|wormbase:WBGene00021473(identity) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:aoAMOcrfpjxDHg+8smQRjOT8yz46239 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 intact-crc:0F3927E59E839A14|rigid:fkY1GnYZKbUXdnCdMBJO1sympnc false - sufficient binding region:222-277 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01761 uniprotkb:Q45FX5 intact:EBI-314725|uniprotkb:Q17362|uniprotkb:Q5W614|uniprotkb:Q5W615|uniprotkb:Q5W616|uniprotkb:Q5W617|uniprotkb:Q646H5|uniprotkb:Q64EQ8|uniprotkb:Q7Z119|uniprotkb:Q7Z120|ensemblmetazoa:C09D1.1b.1|ensemblmetazoa:C09D1.1g.1 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 psi-mi:unc89_caeel(display_long)|uniprotkb:C09D1.1(orf name)|uniprotkb:Uncoordinated protein 89(gene name synonym)|uniprotkb:unc-89(gene name)|psi-mi:unc-89(display_short)|uniprotkb:Obscurin(gene name synonym)|uniprotkb:Inactive serine/threonine-protein kinase unc-89(gene name synonym) psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533401|imex:IM-18681-188 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|refseq:NP_001020984.1|refseq:NP_001020985.1|refseq:NP_001020988.1|refseq:NP_001020989.1|refseq:NP_001020990.1|wormbase:C09D1.1a|wormbase:C09D1.1b|wormbase:C09D1.1c|wormbase:C09D1.1d|wormbase:C09D1.1e|wormbase:C09D1.1f|wormbase:C09D1.1g|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007850(RCSD)|interpro:IPR001452(Src homology-3)|rcsb pdb:1FHO|refseq:NP_001293453.1|refseq:NP_001293454.1|ensemblmetazoa:C09D1.1b.1(transcript)|ensemblmetazoa:C09D1.1g.1(transcript)|ensemblmetazoa:WBGene00006820(gene)|ensemblmetazoa:WBGene00006820(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0014722"(regulation of skeletal muscle contraction by calcium ion signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0090736"(MATH domain binding)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905905"(pharyngeal gland morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR013106(Immunoglobulin V-set)|ensemblmetazoa:WBGene00006820(gene)|uniprotkb:O01761(identity)|wormbase:WBGene00006820(identity) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:84zR3QKMivdFjveSZ43aBEGX/CM6239 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 intact-crc:29357A2E474C36B9|rigid:0T0uGn+sp8cc0rVbG4FklNINjbE false - sufficient binding region:857-918 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:A0A0K3AV08 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-322350|uniprotkb:A0A0K3AS83|uniprotkb:H2KYR3|uniprotkb:Q8T7Z0|ensemblmetazoa:K11D12.10c.1 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:mlk1_caeel(display_long)|uniprotkb:mlk-1(gene name)|psi-mi:mlk-1(display_short)|uniprotkb:Mixed lineage kinase homolog 1(gene name synonym)|uniprotkb:K11D12.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533476|imex:IM-18681-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) wormbase:K11D12.10a|refseq:NP_001300151.1|wormbase:K11D12.10b|wormbase:K11D12.10c|wormbase:K11D12.10d|refseq:NP_001300152.1|refseq:NP_741536.1|refseq:NP_741537.1|ensemblmetazoa:K11D12.10c.1(transcript)|ensemblmetazoa:WBGene00003374(gene)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031103"(axon regeneration)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0046688"(response to copper ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036028|dip:DIP-25180N|uniprotkb:Q8T7Z0(identity)|wormbase:WBGene00003374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/03/30 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:v6Obv6pOk7skWee5xEaNZkz9csw6239 intact-crc:6A68B2791A1DA60D|rigid:2dvk+NLOVzj2X3RPdPIHcjYr8rU false sufficient binding region:857-918 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:O76840 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-312512|uniprotkb:Q22911|uniprotkb:Q8I7I0|uniprotkb:Q8MPV5|ensemblmetazoa:C37C3.6b.1|ensemblmetazoa:C37C3.6b.2 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:ppn1_caeel(display_long)|uniprotkb:mig-6(gene name)|psi-mi:mig-6(display_short)|uniprotkb:C37C3.6(orf name)|uniprotkb:ppn-1(gene name synonym)|uniprotkb:Abnormal cell migration protein 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533431|imex:IM-18681-190 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) ensemblmetazoa:C37C3.6b.1(transcript)|ensemblmetazoa:C37C3.6b.2(transcript)|ensemblmetazoa:WBGene00003242(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002119"(nematode larval development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032504"(multicellular organism reproduction)|go:"GO:0048598"(embryonic morphogenesis)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013273(Peptidase M12B, ADAM-TS)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR020901|interpro:IPR036179|interpro:IPR036383|interpro:IPR036880|reactome:R-CEL-1650814|refseq:NP_505017.1|refseq:NP_505018.1|refseq:NP_741569.1|wormbase:C37C3.6a|wormbase:C37C3.6b|wormbase:C37C3.6c|dip:DIP-24457N|reactome:R-CEL-5173214|uniprotkb:O76840(identity)|wormbase:WBGene00016498(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 68|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:zjt0I9jxT9TLMn1mYen6KEUB/4Y6239 intact-crc:11605434BA232B03|rigid:tAWhtc4YuvDCD6rRhGoaZpSodyA false sufficient binding region:857-918 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:Q19275 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-315168|ensemblmetazoa:F09F7.5a.1|ensemblmetazoa:F09F7.5a.2|ensemblmetazoa:F09F7.5a.3 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:q19275_caeel(display_long)|uniprotkb:CELE_F09F7.5(orf name)|uniprotkb:F09F7.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533446|imex:IM-18681-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) refseq:NP_498186.1|wormbase:F09F7.5a|go:"GO:0005886"(plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035023"(regulation of Rho protein signal transduction)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR036936|interpro:IPR039056|ensemblmetazoa:WBGene00017302(gene)|ensemblmetazoa:F09F7.5a.1(transcript)|ensemblmetazoa:F09F7.5a.2(transcript)|ensemblmetazoa:F09F7.5a.3(transcript)|dip:DIP-25885N|uniprotkb:Q19275(identity)|wormbase:WBGene00017302(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:dRcTzChc6E57GiyrC46iYMLP5Tg6239 intact-crc:08896D3EA2BEBCAB|rigid:T2TnMTUD8uh6nd0qi000vv+BcFE false sufficient binding region:857-918 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:O76337 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-6532169|ensemblmetazoa:F56D2.7.1|uniprotkb:O01421 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:ced6_caeel(display_long)|uniprotkb:ced-6(gene name)|psi-mi:ced-6(display_short)|uniprotkb:Candidate adapter protein ced-6(gene name synonym)|uniprotkb:F56D2.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533461|imex:IM-18681-192 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) ensemblmetazoa:F56D2.7.1(transcript)|ensemblmetazoa:WBGene00000420(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012501"(programmed cell death)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0070986"(left/right axis specification)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|go:"GO:1904747"(positive regulation of apoptotic process involved in development)|go:"GO:0045335"(phagocytic vesicle)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_498203.2|wormbase:F56D2.7|uniprotkb:O76337(identity)|wormbase:WBGene00000420(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 50|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:VjlyH911QZCg4QZbyWiJu1i01cg6239 intact-crc:2589FE91A851F261|rigid:X9x+UeFPT7kFnhebUq+DZxCA+7s false sufficient binding region:857-918 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:O17286 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-325152|ensemblmetazoa:W10D9.4a.1|uniprotkb:A0A0M7RFF4 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:nfyb1_caeel(display_long)|uniprotkb:nfyb-1(gene name)|psi-mi:nfyb-1(display_short)|uniprotkb:CAAT box DNA-binding protein subunit nfyb-1(gene name synonym)|uniprotkb:W10D9.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533523|imex:IM-18681-196 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) refseq:NP_493740.1|ensemblmetazoa:W10D9.4a.1(transcript)|ensemblmetazoa:WBGene00021132(gene)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0043204"(perikaryon)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR027113|wormbase:W10D9.4a|dip:DIP-25261N|wormbase:W10D9.4b|refseq:NP_001303801.1|uniprotkb:O17286(identity)|wormbase:WBGene00021132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:lw5h4Vt6TTJTiU8Bsf29pumUufM6239 intact-crc:B725BB4534D70847|rigid:sw0LYZaiIsUGriOJuyckbHqatUE false sufficient binding region:857-918 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22505 uniprotkb:Q45FX5 intact:EBI-6533495|ensemblmetazoa:T14G11.3.1 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 psi-mi:immt1_caeel(display_long)|uniprotkb:Inner mitochondrial membrane protein 1(gene name synonym)|uniprotkb:Mitofilin homolog 1(gene name synonym)|uniprotkb:T14G11.3(orf name)|uniprotkb:immt-1(gene name)|psi-mi:immt-1(display_short) psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533491|imex:IM-18681-194 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T14G11.3.1(transcript)|ensemblmetazoa:WBGene00020511(gene)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|go:"GO:0070584"(mitochondrion morphogenesis)|interpro:IPR019133|refseq:NP_508475.2|wormbase:T14G11.3|uniprotkb:Q22505(identity)|wormbase:WBGene00020511(identity) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:9pb76nnYSIzJopmTs8VQ5AZIbkE6239 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 intact-crc:E3E592763A9F84DB|rigid:9IQkqYa6JiV/fcxS/jeHjIYjmiA false - sufficient binding region:857-918 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:Q9N5D3 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-315377|uniprotkb:Q9NBD3|ensemblmetazoa:T28F12.3.1 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:sos_caeel(display_long)|uniprotkb:sos-1(gene name)|psi-mi:sos-1(display_short)|uniprotkb:Guanine nucleotide exchange factor for RAS(gene name synonym)|uniprotkb:let-341(gene name synonym)|uniprotkb:T28F12.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533508|imex:IM-18681-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) refseq:NP_504235.2|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR009072(Histone-fold)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR023578|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-186763|reactome:R-CEL-354194|reactome:R-CEL-9013149|reactome:R-CEL-9607240|wormbase:T28F12.3a|ensemblmetazoa:T28F12.3.1(transcript)|ensemblmetazoa:WBGene00004947(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007292"(female gamete generation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016477"(cell migration)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR035899|interpro:IPR036964|reactome:R-CEL-179812|reactome:R-CEL-193648|reactome:R-CEL-1963640|reactome:R-CEL-2179392|reactome:R-CEL-375165|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5673001|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-416482|uniprotkb:Q9N5D3(identity)|wormbase:WBGene00004947(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:oK9Np48YGS1YCmBVWJNZ5NM2osA6239 intact-crc:67CEA2D58C5E0CEE|rigid:jmRn0fe94meldSG8KIZUalG9kDM false sufficient binding region:857-918 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34708 uniprotkb:Q45FX5 intact:EBI-367204|uniprotkb:Q95Q22|uniprotkb:Q9U2C0|ensemblmetazoa:Y47D3A.6a.1 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 psi-mi:tra1_caeel(display_long)|uniprotkb:tra-1(gene name)|psi-mi:tra-1(display_short)|uniprotkb:her-2(gene name synonym)|uniprotkb:Y47D3A.6(orf name)|uniprotkb:Hermaphrodization of XO animals protein 2(gene name synonym) psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533570|imex:IM-18681-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y47D3A.6a|wormbase:Y47D3A.6b|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensemblmetazoa:WBGene00006604(gene)|ensemblmetazoa:Y47D3A.6a.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008406"(gonad development)|go:"GO:0019099"(female germ-line sex determination)|go:"GO:0030154"(cell differentiation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0019101"(female somatic sex determination)|interpro:IPR036236|uniprotkb:P34708(identity)|wormbase:WBGene00006604(identity) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:68IEYezaTV2jJDkpyyxTmNIzA6w6239 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 intact-crc:7D036995FD166864|rigid:r8lsmv9bg6nCv+GjqneoC8rOd6U false - sufficient binding region:857-918 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q45FX5 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533540|imex:IM-18681-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 intact-crc:067D6BCCE99C8FBE|rigid:xuHARaVfVgfPyl5lU0KH+nmcdtU false - sufficient binding region:857-918 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6A573 uniprotkb:Q45FX5 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533555|imex:IM-18681-198 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 intact-crc:3BDB566D7408BA48|rigid:KpxuZpe2xWFrfxhZwdtv7hY0+UY false - sufficient binding region:857-918 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:P39055 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533636|imex:IM-18681-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 26|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:3807192CEF4ED693|rigid:XZzYueX7jfKhetDylaffWuDKYLA false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:Q9UB01 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-6533589|ensemblmetazoa:Y4C6B.1.1 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:q9ub01_caeel(display_long)|uniprotkb:CELE_Y4C6B.1(orf name)|uniprotkb:Y4C6B.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533585|imex:IM-18681-200 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) ensemblmetazoa:WBGene00021155(gene)|ensemblmetazoa:Y4C6B.1.1(transcript)|refseq:NP_500786.1|wormbase:Y4C6B.1|uniprotkb:Q9UB01(identity)|wormbase:WBGene00021155(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 13|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:z00tk6D2d6frL+hGJ2HSZ72CNcs6239 intact-crc:C8FB8009C19EE743|rigid:nyOeOTgDez2idO//ei/GOEVBg+Q false sufficient binding region:857-918 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:G5EGT7 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-6533606|ensemblmetazoa:Y54F10BM.2.1 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:g5egt7_caeel(display_long)|uniprotkb:iffb-1(gene name)|psi-mi:iffb-1(display_short)|uniprotkb:Translation initiation factor IF-2(gene name synonym)|uniprotkb:CELE_Y54F10BM.2(orf name)|uniprotkb:Y54F10BM.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533602|imex:IM-18681-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) ensemblmetazoa:WBGene00021857(gene)|ensemblmetazoa:Y54F10BM.2.1(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR023115|refseq:NP_497536.2|wormbase:Y54F10BM.2|reactome:R-CEL-72706|interpro:IPR027417|interpro:IPR036925|uniprotkb:G5EGT7(identity)|wormbase:WBGene00021857(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:2LL01AMSoVweWZyC8uB10ime8ko6239 intact-crc:68B19E370A9731B6|rigid:Wi7Sri7IEUgSdsp2stHhDjz0Ge4 false sufficient binding region:857-918 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:Q9U1W1 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-315106|ensemblmetazoa:Y63D3A.5.1|ensemblmetazoa:Y63D3A.5.2 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:tfg_caeel(display_long)|uniprotkb:tfg-1(gene name)|psi-mi:tfg-1(display_short)|uniprotkb:Y63D3A.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533619|imex:IM-18681-202 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) refseq:NP_493462.1|wormbase:Y63D3A.5|ensemblmetazoa:WBGene00006565(gene)|ensemblmetazoa:Y63D3A.5.1(transcript)|ensemblmetazoa:Y63D3A.5.2(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009306"(protein secretion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072595"(maintenance of protein localization in organelle)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|dip:DIP-26017N|reactome:R-CEL-204005|uniprotkb:Q9U1W1(identity)|wormbase:WBGene00006565(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:nqyc7+EyDkiVah2+12hsLFWeNdA6239 intact-crc:41C0D5A8973476F5|rigid:iXNdZOx64x9j7jmWDm8ehL+m2cU false sufficient binding region:857-918 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A1C3NSL9 uniprotkb:Q19253 intact:EBI-327553|ensemblmetazoa:C25A11.4k.1|intact:EBI-11468732|uniprotkb:A0A1C3NSK1|uniprotkb:A0A1C3NSK9|uniprotkb:A0A1C3NSL1|uniprotkb:A0A1C3NSL6|uniprotkb:A0A1C3NSM8|uniprotkb:A0A1C3NSP2|uniprotkb:A0A1C3NSQ2|uniprotkb:G4RTG4|uniprotkb:H2KYC4|uniprotkb:H2KYC6 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:ajm1_caeel(display_long)|uniprotkb:ajm-1(gene name)|psi-mi:ajm-1(display_short)|uniprotkb:CELE_C25A11.4(orf name)|uniprotkb:C25A11.4(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533681|imex:IM-18681-206 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q18138(uniprot-removed-ac)|interpro:IPR038825|wormbase:C25A11.4e|interpro:IPR002893(Zinc finger, MYND-type)|ensemblmetazoa:C25A11.4k.1(transcript)|ensemblmetazoa:WBGene00000100(gene)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044292"(dendrite terminus)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046872"(metal ion binding)|refseq:NP_001317735.1|refseq:NP_001317736.1|refseq:NP_001317888.1|refseq:NP_001317890.1|refseq:NP_001317891.1|refseq:NP_001317897.1|refseq:NP_001317898.1|refseq:NP_001317899.1|refseq:NP_509536.1|refseq:NP_001317887.1|refseq:NP_001317889.1|wormbase:C25A11.4a|wormbase:C25A11.4d|wormbase:C25A11.4f|wormbase:C25A11.4g|wormbase:C25A11.4h|wormbase:C25A11.4i|wormbase:C25A11.4j|wormbase:C25A11.4k|wormbase:C25A11.4l|wormbase:C25A11.4m|uniprotkb:G4RTG4(identity)|wormbase:WBGene00000100(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/26 rogid:r7BJygBJ3u4aJy/4+mWnsMDUgLo6239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:0A0630DF049DE582|rigid:C+wLQQnYYe2jYnm4CybJTPXsN/U false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:O17578 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-2412885|ensemblmetazoa:C06H5.2.1 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:o17578_caeel(display_long)|uniprotkb:fbxa-157(gene name)|psi-mi:fbxa-157(display_short)|uniprotkb:CELE_C06H5.2(orf name)|uniprotkb:C06H5.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533651|imex:IM-18681-204 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) interpro:IPR002900(Protein of unknown function DUF38, Caenorhabditis species)|interpro:IPR001810(Cyclin-like F-box)|refseq:NP_507510.2|wormbase:C06H5.2|interpro:IPR040161|interpro:IPR041426|ensemblmetazoa:C06H5.2.1(transcript)|ensemblmetazoa:WBGene00007393(gene)|uniprotkb:O17578(identity)|wormbase:WBGene00007393(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:PlA69aJK2lvnlHqJSwsVMZojJFU6239 intact-crc:B5E853E7EA512539|rigid:NaY8i8vpnM0QIYY7G2wQ7CEj4CI false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:Q19253 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533666|imex:IM-18681-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 33|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:10CEE304E8DF8580|rigid:u61EiF9EUYnp4Tl1xgvr4UrrkhQ false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED57 uniprotkb:Q19253 intact:EBI-327853|ensemblmetazoa:F22E12.1.1 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:g5ed57_caeel(display_long)|uniprotkb:F22E12.1(orf name)|uniprotkb:CELE_F22E12.1(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533743|imex:IM-18681-210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O45916(uniprot-removed-ac)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR020901|refseq:NP_505684.2|wormbase:F22E12.1|ensemblmetazoa:F22E12.1.1(transcript)|ensemblmetazoa:WBGene00009058(gene)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036880|uniprotkb:G5ED57(identity)|wormbase:WBGene00009058(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 27|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:+Rdyx7pnykvpAExFI2L56AHfbIc6239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:EABCEE314B26CB9B|rigid:kiUbTash6eFDTpeMqNVMIcyuxBk false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:Q9XZI6 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-311866|uniprotkb:Q95Q72|uniprotkb:Q95Q73|uniprotkb:Q95Q74|uniprotkb:Q95Q75|uniprotkb:Q9UA04|uniprotkb:Q9UA05|uniprotkb:Q9XZI7|uniprotkb:Q9XZI8|uniprotkb:Q9XZI9|ensemblmetazoa:C32E8.10a.1 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:pical_caeel(display_long)|uniprotkb:C32E8.10(orf name)|uniprotkb:unc-11(gene name)|psi-mi:unc-11(display_short)|uniprotkb:AP180-like adaptor protein(gene name synonym)|uniprotkb:Uncoordinated protein 11(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533696|imex:IM-18681-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) ensemblmetazoa:C32E8.10a.1(transcript)|ensemblmetazoa:WBGene00006751(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0040011"(locomotion)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:1902683"(regulation of receptor localization to synapse)|go:"GO:1903539"(protein localization to postsynaptic membrane)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|refseq:NP_001021014.1|refseq:NP_001021015.1|refseq:NP_001021016.1|refseq:NP_491227.1|refseq:NP_491228.1|refseq:NP_491229.1|refseq:NP_491230.1|wormbase:C32E8.10a|wormbase:C32E8.10b|wormbase:C32E8.10c|wormbase:C32E8.10d|wormbase:C32E8.10e|wormbase:C32E8.10f|wormbase:C32E8.10h|reactome:R-CEL-432722|reactome:R-CEL-8856825|reactome:R-CEL-8856828|dip:DIP-25315N|uniprotkb:Q9XZI6(identity)|wormbase:WBGene00006751(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:4JQIZTgKSv8kTdP9aYTzoTQp6L06239 intact-crc:672111BA8E78FF82|rigid:SQ8AZhX5VhsQW63KCbOqy5scGZQ false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B7WN72 uniprotkb:Q19253 intact:EBI-2914750|ensemblmetazoa:C33B4.3c.1|uniprotkb:Q09493|uniprotkb:Q7JMK1 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:shank_caeel(display_long)|uniprotkb:shn-1(gene name)|psi-mi:shn-1(display_short)|uniprotkb:C33B4.3(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533711|imex:IM-18681-208 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C33B4.3c.1(transcript)|ensemblmetazoa:WBGene00006444(gene)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030421"(defecation)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043197"(dendritic spine)|reactome:R-CEL-6794361|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|wormbase:C33B4.3c|wormbase:C33B4.3a|wormbase:C33B4.3b|refseq:NP_001254297.1|interpro:IPR036034|interpro:IPR036770|refseq:NP_001022006.1|refseq:NP_001022007.1|uniprotkb:B7WN72(identity)|wormbase:WBGene00006444(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MxlKCcp7iFWP6a9kDPFIvqKhOlY6239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:937F78690EAEA9E8|rigid:VETTUo7aHKFEkttVhGwyRjHj6kI false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:Q93343 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-6533726|ensemblmetazoa:C36B1.9.1 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:q93343_caeel(display_long)|uniprotkb:CELE_C36B1.9(orf name)|uniprotkb:C36B1.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533728|imex:IM-18681-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) ensemblmetazoa:C36B1.9.1(transcript)|ensemblmetazoa:WBGene00007976(gene)|go:"GO:0046872"(metal ion binding)|interpro:IPR027370|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|refseq:NP_492366.1|wormbase:C36B1.9|mint:Q93343|uniprotkb:Q93343(identity)|wormbase:WBGene00007976(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:FVJcmVuzj4ods6Sk6Zqy92a5EAs6239 intact-crc:E7E20A6EB2A0A392|rigid:c1m85VfO8d/mswI+SOH3vn5gokk false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20877 uniprotkb:Q19253 intact:EBI-315480|ensemblmetazoa:F56D3.1.1|ensemblmetazoa:F56D3.1.2 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:q20877_caeel(display_long)|uniprotkb:F56D3.1(orf name)|uniprotkb:CELE_F56D3.1(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533788|imex:IM-18681-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494727.1|wormbase:F56D3.1|ensemblmetazoa:F56D3.1.1(transcript)|ensemblmetazoa:F56D3.1.2(transcript)|ensemblmetazoa:WBGene00018969(gene)|dip:DIP-24648N|uniprotkb:Q20877(identity)|wormbase:WBGene00018969(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:AUv5Clc1XXnuucrO63ViEf7UQV46239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:960815CDF4FD13FB|rigid:dy64WGfe49mVDcQm4fHOzs8yA7k false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:Q19782 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-320224|ensemblmetazoa:F25E2.4.1 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:ifd2_caeel(display_long)|uniprotkb:ifd-2(gene name)|psi-mi:ifd-2(display_short)|uniprotkb:F25E2.4(orf name)|uniprotkb:Intermediate filament protein D2(gene name synonym)|uniprotkb:Cel IF D2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533758|imex:IM-18681-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) refseq:NP_508160.1|wormbase:F25E2.4|ensemblmetazoa:F25E2.4.1(transcript)|ensemblmetazoa:WBGene00002058(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-24353N|uniprotkb:Q19782(identity)|wormbase:WBGene00002058(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:88VvVnae9HlEVXvOcl3pryPLe5g6239 intact-crc:FFBFADB9845633BD|rigid:YCSMyDzbs3cASXTJ88S5RQ/rk2A false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:Q20010 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533773|imex:IM-18681-212 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N|uniprotkb:Q20010(identity)|wormbase:WBGene00009385(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 intact-crc:B96B9870E82B0D90|rigid:beTrXM1Ve8zdNLyUgT3KsbhC71w false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:G5EFY6 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-317770|ensemblmetazoa:T01G1.3.1|ensemblmetazoa:T01G1.3.2|ensemblmetazoa:T01G1.3.3 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:g5efy6_caeel(display_long)|uniprotkb:T01G1.3(orf name)|uniprotkb:sec-31(gene name)|psi-mi:sec-31(display_short)|uniprotkb:CELE_T01G1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533833|imex:IM-18681-216 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) uniprotkb:O45604(uniprot-removed-ac)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_502144.1|interpro:IPR040251|reactome:R-CEL-204005|wormbase:T01G1.3|ensemblmetazoa:T01G1.3.1(transcript)|ensemblmetazoa:T01G1.3.2(transcript)|ensemblmetazoa:T01G1.3.3(transcript)|ensemblmetazoa:WBGene00011338(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR036322|uniprotkb:G5EFY6(identity)|wormbase:WBGene00011338(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:FVZWQhc6ZjDGweaz8DeSFuMo9Zg6239 intact-crc:47CD22E1183EAADB|rigid:kMnBRXrXRUHHBNNyUDZoAxuqW+c false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:Q94246 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-6461124|ensemblmetazoa:F57F4.3.1 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:q94246_caeel(display_long)|uniprotkb:F57F4.3(orf name)|uniprotkb:gfi-1(gene name)|psi-mi:gfi-1(display_short)|uniprotkb:CELE_F57F4.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533803|imex:IM-18681-214 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) ensemblmetazoa:F57F4.3.1(transcript)|ensemblmetazoa:WBGene00001581(gene)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0045121"(membrane raft)|interpro:IPR002603(Protein of unknown function ET)|refseq:NP_504626.1|wormbase:F57F4.3|uniprotkb:Q94246(identity)|wormbase:WBGene00001581(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:Dap7huO6cWZv2f48TbdB1CMIcdg6239 intact-crc:593B1929DA5C597E|rigid:mxjVg4yvAbuKXpOOJ5dJanYiGcE false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01900 uniprotkb:Q19253 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533818|imex:IM-18681-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:459159F39AC07672|rigid:+D2AFwORQvxRoxqUSNwu0uim/Ok false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:G5EF97 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-6533878|ensemblmetazoa:Y116A8C.32a.1 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:g5ef97_caeel(display_long)|uniprotkb:CELE_Y116A8C.32(orf name)|uniprotkb:sfa-1(gene name)|psi-mi:sfa-1(display_short)|uniprotkb:sf1(gene name synonym)|uniprotkb:Y116A8C.32(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533880|imex:IM-18681-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) ensemblmetazoa:WBGene00013808(gene)|ensemblmetazoa:Y116A8C.32a.1(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR031150|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|refseq:NP_503033.1|interpro:IPR032570|wormbase:Y116A8C.32a|interpro:IPR036612|interpro:IPR036875|uniprotkb:G5EF97(identity)|wormbase:WBGene00013808(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:xmmvcePSQn9wlfICddQs3ghsr9s6239 intact-crc:2323DDD7CFF5C7B7|rigid:Bq5ZwbkhQwl/GGPp/UFpuYJ5luI false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:Q9U304 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-329038|ensemblmetazoa:Y106G6D.7.1 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:q9u304_caeel(display_long)|uniprotkb:rbm-12(gene name)|psi-mi:rbm-12(display_short)|uniprotkb:CELE_Y106G6D.7(orf name)|uniprotkb:Y106G6D.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533863|imex:IM-18681-218 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) refseq:NP_492671.1|wormbase:Y106G6D.7|dip:DIP-26480N|ensemblmetazoa:WBGene00013703(gene)|ensemblmetazoa:Y106G6D.7.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-CEL-72163|uniprotkb:Q9U304(identity)|wormbase:WBGene00013703(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:/8MJkmHgCyjvgK0ZmDnklHVfJrw6239 intact-crc:0009B75CCE6D986A|rigid:CiSm6/UmEdZepSDvO9EEygIcaYQ false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q19253 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533848|imex:IM-18681-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 19|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:B67C05C8DD2FADA0|rigid:gzWfLPZ3aKuZTGnATAXDUC/5WU0 false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A8WFL0 uniprotkb:Q19253 intact:EBI-6533929|ensemblmetazoa:ZK381.5b.1 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:a8wfl0_caeel(display_long)|uniprotkb:ZK381.5(orf name)|uniprotkb:prkl-1(gene name)|psi-mi:prkl-1(display_short)|uniprotkb:CELE_ZK381.5(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533925|imex:IM-18681-222 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00022727(gene)|ensemblmetazoa:ZK381.5b.1(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_741436.2|wormbase:ZK381.5b|uniprotkb:A8WFL0(identity)|wormbase:WBGene00022727(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:fcmrkFYkH8buNRyUpTMTG+NeuoM6239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:E7CD7A41BBF8EE22|rigid:wOJ5spG+rW+/Tp3zIMIk4k2/ShM false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A5PEX6 uniprotkb:Q19253 intact:EBI-6532321|ensemblmetazoa:Y57A10A.18b.1|ensemblmetazoa:Y57A10A.18b.2 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:a5pex6_caeel(display_long)|uniprotkb:Y57A10A.18(orf name)|uniprotkb:pqn-87(gene name)|psi-mi:pqn-87(display_short)|uniprotkb:CELE_Y57A10A.18(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533895|imex:IM-18681-220 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004167(gene)|ensemblmetazoa:Y57A10A.18b.1(transcript)|ensemblmetazoa:Y57A10A.18b.2(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|refseq:NP_001122665.1|wormbase:Y57A10A.18b|uniprotkb:A5PEX6(identity)|wormbase:WBGene00004167(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:U79ecDJtHc4bqHRcr6eBglpyv5k6239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:A0E1DACF76CB4C19|rigid:jjaUgenMSi7O6RKxYBOBIKkrmqQ false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q4VNJ8 uniprotkb:Q19253 intact:EBI-2918529 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533910|imex:IM-18681-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 15|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:5B71125C78F1FA83|rigid:PwXAPhJku0YGfSyqfrSGz2pDOWo false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54936 uniprotkb:O76840 intact:EBI-315019|ensemblmetazoa:F17E5.1a.1 intact:EBI-312512|uniprotkb:Q22911|uniprotkb:Q8I7I0|uniprotkb:Q8MPV5|ensemblmetazoa:C37C3.6b.1|ensemblmetazoa:C37C3.6b.2 psi-mi:lin2_caeel(display_long)|uniprotkb:lin-2(gene name)|psi-mi:lin-2(display_short)|uniprotkb:F17E5.1(orf name)|uniprotkb:Abnormal cell lineage protein 2(gene name synonym) psi-mi:ppn1_caeel(display_long)|uniprotkb:mig-6(gene name)|psi-mi:mig-6(display_short)|uniprotkb:C37C3.6(orf name)|uniprotkb:ppn-1(gene name synonym)|uniprotkb:Abnormal cell migration protein 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533972|imex:IM-18681-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024587.1|refseq:NP_001024588.1|wormbase:F17E5.1a|wormbase:F17E5.1b|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|mint:P54936|interpro:IPR027417|go:"GO:0005886"(plasma membrane)|ensemblmetazoa:F17E5.1a.1(transcript)|ensemblmetazoa:WBGene00002991(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0018991"(oviposition)|go:"GO:0030054"(cell junction)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|reactome:R-CEL-212676|reactome:R-CEL-6794361|go:"GO:0009791"(post-embryonic development)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036034|uniprotkb:P54936(identity)|wormbase:WBGene00002991(identity) ensemblmetazoa:C37C3.6b.1(transcript)|ensemblmetazoa:C37C3.6b.2(transcript)|ensemblmetazoa:WBGene00003242(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002119"(nematode larval development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032504"(multicellular organism reproduction)|go:"GO:0048598"(embryonic morphogenesis)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR010909(PLAC)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013273(Peptidase M12B, ADAM-TS)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR020901|interpro:IPR036179|interpro:IPR036383|interpro:IPR036880|reactome:R-CEL-1650814|refseq:NP_505017.1|refseq:NP_505018.1|refseq:NP_741569.1|wormbase:C37C3.6a|wormbase:C37C3.6b|wormbase:C37C3.6c|dip:DIP-24457N|reactome:R-CEL-5173214|uniprotkb:O76840(identity)|wormbase:WBGene00016498(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:j61SyO9dClve7AUT9ljEmQrMwvk6239 rogid:zjt0I9jxT9TLMn1mYen6KEUB/4Y6239 intact-crc:B482984085A5BA40|rigid:WujIVRIeHcPO4slQ0xbWEo8ldRE false sufficient binding region:636-716 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:Q23571 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-330837|ensemblmetazoa:ZK669.4.1 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:odb2_caeel(display_long)|uniprotkb:dbt-1(gene name)|psi-mi:dbt-1(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase complex component E2(gene name synonym)|uniprotkb:Dihydrolipoamide branched-chain transacylase E2(gene name synonym)|uniprotkb:ZK669.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533942|imex:IM-18681-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) reactome:R-CEL-70895|refseq:NP_495670.1|wormbase:ZK669.4|reactome:R-CEL-389661|dip:DIP-26430N|ensemblmetazoa:WBGene00014054(gene)|ensemblmetazoa:ZK669.4.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031405"(lipoic acid binding)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043005"(neuron projection)|go:"GO:0043754"("dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity")|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0061063"(positive regulation of nematode larval development)|go:"GO:1901046"(positive regulation of oviposition)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|reactome:R-CEL-9013407|uniprotkb:Q23571(identity)|wormbase:WBGene00014054(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:HWZBiffVN9j8rIxCNlge5bQBwGs6239 intact-crc:ECF7702458D9E19C|rigid:nKx7seBf56UwKXzDxhaOc7uAEf4 false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06125 uniprotkb:P54936 intact:EBI-324126|ensemblmetazoa:C04F6.1.1 intact:EBI-315019|ensemblmetazoa:F17E5.1a.1 psi-mi:vit5_caeel(display_long)|uniprotkb:vit-5(gene name)|psi-mi:vit-5(display_short)|uniprotkb:C04F6.1(orf name) psi-mi:lin2_caeel(display_long)|uniprotkb:lin-2(gene name)|psi-mi:lin-2(display_short)|uniprotkb:F17E5.1(orf name)|uniprotkb:Abnormal cell lineage protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533957|imex:IM-18681-224 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508589.1|wormbase:C04F6.1|ensemblmetazoa:C04F6.1.1(transcript)|ensemblmetazoa:WBGene00006929(gene)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0045735"(nutrient reservoir activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|dip:DIP-25459N|uniprotkb:P06125(identity)|wormbase:WBGene00006929(identity) refseq:NP_001024587.1|refseq:NP_001024588.1|wormbase:F17E5.1a|wormbase:F17E5.1b|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|mint:P54936|interpro:IPR027417|go:"GO:0005886"(plasma membrane)|ensemblmetazoa:F17E5.1a.1(transcript)|ensemblmetazoa:WBGene00002991(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0018991"(oviposition)|go:"GO:0030054"(cell junction)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|reactome:R-CEL-212676|reactome:R-CEL-6794361|go:"GO:0009791"(post-embryonic development)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036034|uniprotkb:P54936(identity)|wormbase:WBGene00002991(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:pT6TLFplGNUDnnOPPZwpVh49wms6239 rogid:j61SyO9dClve7AUT9ljEmQrMwvk6239 intact-crc:E27C7C01FF2B2B22|rigid:Wb+OmlplxvCwBZQ1taOGhztpBv4 false - sufficient binding region:636-716 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91820 uniprotkb:P54936 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 intact:EBI-315019|ensemblmetazoa:F17E5.1a.1 psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:lin2_caeel(display_long)|uniprotkb:lin-2(gene name)|psi-mi:lin-2(display_short)|uniprotkb:F17E5.1(orf name)|uniprotkb:Abnormal cell lineage protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534021|imex:IM-18681-228 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N|uniprotkb:P91820(identity)|wormbase:WBGene00003083(identity) refseq:NP_001024587.1|refseq:NP_001024588.1|wormbase:F17E5.1a|wormbase:F17E5.1b|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|mint:P54936|interpro:IPR027417|go:"GO:0005886"(plasma membrane)|ensemblmetazoa:F17E5.1a.1(transcript)|ensemblmetazoa:WBGene00002991(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0018991"(oviposition)|go:"GO:0030054"(cell junction)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|reactome:R-CEL-212676|reactome:R-CEL-6794361|go:"GO:0009791"(post-embryonic development)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036034|uniprotkb:P54936(identity)|wormbase:WBGene00002991(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 rogid:j61SyO9dClve7AUT9ljEmQrMwvk6239 intact-crc:095247B87379016A|rigid:H1rabCViGFgf6gFopkNLk3cezKI false - sufficient binding region:636-716 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6533991 uniprotkb:P54936 - intact:EBI-315019|ensemblmetazoa:F17E5.1a.1 psi-mi:q8mnx8_caeel(display_short)|psi-mi:EBI-6533991(display_long)|uniprotkb:F56D12.5(orf name)|uniprotkb:vig-1(gene name)|psi-mi:vig-1(display_short)|uniprotkb:CELE_F56D12.5(orf name) psi-mi:lin2_caeel(display_long)|uniprotkb:lin-2(gene name)|psi-mi:lin-2(display_short)|uniprotkb:F17E5.1(orf name)|uniprotkb:Abnormal cell lineage protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6533987|imex:IM-18681-226 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8MNX8(uniprot-removed-ac)|uniprotkb:Q8MNX8(identity)|wormbase:WBGene00006924(identity) refseq:NP_001024587.1|refseq:NP_001024588.1|wormbase:F17E5.1a|wormbase:F17E5.1b|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|mint:P54936|interpro:IPR027417|go:"GO:0005886"(plasma membrane)|ensemblmetazoa:F17E5.1a.1(transcript)|ensemblmetazoa:WBGene00002991(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0018991"(oviposition)|go:"GO:0030054"(cell junction)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|reactome:R-CEL-212676|reactome:R-CEL-6794361|go:"GO:0009791"(post-embryonic development)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036034|uniprotkb:P54936(identity)|wormbase:WBGene00002991(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:fel9LIN7E6kt9hmPvZTvidYco1c6239 rogid:j61SyO9dClve7AUT9ljEmQrMwvk6239 intact-crc:1BEE0C0821917FB1|rigid:prghczOzVft0sVZb+Ue2qfUdODo false - sufficient binding region:636-716 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54936 uniprotkb:Q1ZXS5 intact:EBI-315019|ensemblmetazoa:F17E5.1a.1 intact:EBI-318975|uniprotkb:Q9XUQ4|uniprotkb:A8JJR1|ensemblmetazoa:T08G5.5b.1|intact:EBI-14973910|intact:EBI-6534008 psi-mi:lin2_caeel(display_long)|uniprotkb:lin-2(gene name)|psi-mi:lin-2(display_short)|uniprotkb:F17E5.1(orf name)|uniprotkb:Abnormal cell lineage protein 2(gene name synonym) psi-mi:vps39_caeel(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534004|imex:IM-18681-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024587.1|refseq:NP_001024588.1|wormbase:F17E5.1a|wormbase:F17E5.1b|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|mint:P54936|interpro:IPR027417|go:"GO:0005886"(plasma membrane)|ensemblmetazoa:F17E5.1a.1(transcript)|ensemblmetazoa:WBGene00002991(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0018991"(oviposition)|go:"GO:0030054"(cell junction)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|reactome:R-CEL-212676|reactome:R-CEL-6794361|go:"GO:0009791"(post-embryonic development)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036034|uniprotkb:P54936(identity)|wormbase:WBGene00002991(identity) refseq:NP_001041163.1|wormbase:T08G5.5a|refseq:NP_001041164.1|refseq:NP_001123010.1|wormbase:T08G5.5b|wormbase:T08G5.5c|ensemblmetazoa:T08G5.5b.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|interpro:IPR001180(Citron-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019452|interpro:IPR019453|interpro:IPR032914|interpro:IPR036322|dip:DIP-24817N|uniprotkb:A8JJR1(identity)|wormbase:WBGene00011625(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2017/10/20 rogid:j61SyO9dClve7AUT9ljEmQrMwvk6239 rogid:OY+zb1zby7cfHD+BQwKt56yw7HY6239 intact-crc:891430FD2085323C|rigid:I0+VB5u46HCtH4idiDf8FVDu2p4 false sufficient binding region:636-716 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19275 uniprotkb:Q19901 intact:EBI-315168|ensemblmetazoa:F09F7.5a.1|ensemblmetazoa:F09F7.5a.2|ensemblmetazoa:F09F7.5a.3 intact:EBI-326658|ensemblmetazoa:F29D10.4.1 psi-mi:q19275_caeel(display_long)|uniprotkb:CELE_F09F7.5(orf name)|uniprotkb:F09F7.5(orf name) psi-mi:q19901_caeel(display_long)|uniprotkb:hum-1(gene name)|psi-mi:hum-1(display_short)|uniprotkb:CELE_F29D10.4(orf name)|uniprotkb:F29D10.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534070|imex:IM-18681-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498186.1|wormbase:F09F7.5a|go:"GO:0005886"(plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035023"(regulation of Rho protein signal transduction)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR036936|interpro:IPR039056|ensemblmetazoa:WBGene00017302(gene)|ensemblmetazoa:F09F7.5a.1(transcript)|ensemblmetazoa:F09F7.5a.2(transcript)|ensemblmetazoa:F09F7.5a.3(transcript)|dip:DIP-25885N|uniprotkb:Q19275(identity)|wormbase:WBGene00017302(identity) refseq:NP_492393.1|wormbase:F29D10.4|ensemblmetazoa:F29D10.4.1(transcript)|ensemblmetazoa:WBGene00002035(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR025660|interpro:IPR027417|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|dip:DIP-24485N|uniprotkb:Q17382(identity)|wormbase:WBGene00002035(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 127|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:dRcTzChc6E57GiyrC46iYMLP5Tg6239 rogid:COaNIVxftB8ggxM7ESkx2eOU3Q06239 intact-crc:9BEFBA636FB1F377|rigid:jKsSCq8PaP2pj9tEoAGgZ1QB/o0 false - sufficient binding region:1047-1100 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54936 uniprotkb:D0IMZ5 intact:EBI-315019|ensemblmetazoa:F17E5.1a.1 intact:EBI-6534036|ensemblmetazoa:Y66H1B.2a.1 psi-mi:lin2_caeel(display_long)|uniprotkb:lin-2(gene name)|psi-mi:lin-2(display_short)|uniprotkb:F17E5.1(orf name)|uniprotkb:Abnormal cell lineage protein 2(gene name synonym) psi-mi:d0imz5_caeel(display_long)|uniprotkb:Y66H1B.2(orf name)|uniprotkb:fln-1(gene name)|psi-mi:fln-1(display_short)|uniprotkb:CELE_Y66H1B.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534038|imex:IM-18681-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024587.1|refseq:NP_001024588.1|wormbase:F17E5.1a|wormbase:F17E5.1b|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|mint:P54936|interpro:IPR027417|go:"GO:0005886"(plasma membrane)|ensemblmetazoa:F17E5.1a.1(transcript)|ensemblmetazoa:WBGene00002991(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0018991"(oviposition)|go:"GO:0030054"(cell junction)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|reactome:R-CEL-212676|reactome:R-CEL-6794361|go:"GO:0009791"(post-embryonic development)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036034|uniprotkb:P54936(identity)|wormbase:WBGene00002991(identity) ensemblmetazoa:WBGene00022048(gene)|ensemblmetazoa:Y66H1B.2a.1(transcript)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0061038"(uterus morphogenesis)|interpro:IPR044801|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|refseq:NP_001023550.2|wormbase:Y66H1B.2a|interpro:IPR036872|uniprotkb:D0IMZ5(identity)|wormbase:WBGene00022048(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:j61SyO9dClve7AUT9ljEmQrMwvk6239 rogid:9hCmcqWxWSY2QYeg05bDz4qoY/U6239 intact-crc:540185523A5BE02C|rigid:IJK9EjELOwkn/MiKp4lmUnaroXA false sufficient binding region:636-716 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDW5 uniprotkb:Q19901 intact:EBI-2411899|ensemblmetazoa:C04A11.4a.1 intact:EBI-326658|ensemblmetazoa:F29D10.4.1 psi-mi:g5edw5_caeel(display_long)|uniprotkb:adm-2(gene name)|psi-mi:adm-2(display_short)|uniprotkb:C04A11.4(orf name)|uniprotkb:CELE_C04A11.4(orf name) psi-mi:q19901_caeel(display_long)|uniprotkb:hum-1(gene name)|psi-mi:hum-1(display_short)|uniprotkb:CELE_F29D10.4(orf name)|uniprotkb:F29D10.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534053|imex:IM-18681-230 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O17569(uniprot-removed-ac)|wormbase:C04A11.4a|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR024079|refseq:NP_510291.1|reactome:R-CEL-6798695|interpro:IPR034027|interpro:IPR036436|reactome:R-CEL-1474228|ensemblmetazoa:C04A11.4a.1(transcript)|ensemblmetazoa:WBGene00000074(gene)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|uniprotkb:G5EDW5(identity)|wormbase:WBGene00000074(identity) refseq:NP_492393.1|wormbase:F29D10.4|ensemblmetazoa:F29D10.4.1(transcript)|ensemblmetazoa:WBGene00002035(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR025660|interpro:IPR027417|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|dip:DIP-24485N|uniprotkb:Q17382(identity)|wormbase:WBGene00002035(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:iJQB3mLYJDHdG8uP+O5Uuvcv+SQ6239 rogid:COaNIVxftB8ggxM7ESkx2eOU3Q06239 intact-crc:75C76043862CDCCA|rigid:cTdvAqImsWj9vGbnw7XZ/8e0OdA false - sufficient binding region:1047-1100 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:Q10929 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534132|imex:IM-18681-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 intact-crc:C0150F383D965F9E|rigid:LMu43ivWaR5rEdxT248iErBXeos false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19901 uniprotkb:P91482 intact:EBI-326658|ensemblmetazoa:F29D10.4.1 intact:EBI-315371|ensemblmetazoa:T20F5.6.1 psi-mi:q19901_caeel(display_long)|uniprotkb:hum-1(gene name)|psi-mi:hum-1(display_short)|uniprotkb:CELE_F29D10.4(orf name)|uniprotkb:F29D10.4(orf name) psi-mi:p91482_caeel(display_long)|uniprotkb:T20F5.6(orf name)|uniprotkb:CELE_T20F5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534085|imex:IM-18681-232 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492393.1|wormbase:F29D10.4|ensemblmetazoa:F29D10.4.1(transcript)|ensemblmetazoa:WBGene00002035(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR025660|interpro:IPR027417|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|dip:DIP-24485N|uniprotkb:Q17382(identity)|wormbase:WBGene00002035(identity) refseq:NP_491266.1|wormbase:T20F5.6|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|ensemblmetazoa:T20F5.6.1(transcript)|ensemblmetazoa:WBGene00020628(gene)|go:"GO:0046872"(metal ion binding)|uniprotkb:P91482(identity)|wormbase:WBGene00020628(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 217|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:COaNIVxftB8ggxM7ESkx2eOU3Q06239 rogid:XgUfhY6bbYdTU31B8yVQiDR2+KA6239 intact-crc:215C69F86C3EC495|rigid:MnJlcDoD4vRQ0+tNEWHKoaNYkRM false sufficient binding region:1047-1100 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19901 uniprotkb:Q6A573 intact:EBI-326658|ensemblmetazoa:F29D10.4.1 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:q19901_caeel(display_long)|uniprotkb:hum-1(gene name)|psi-mi:hum-1(display_short)|uniprotkb:CELE_F29D10.4(orf name)|uniprotkb:F29D10.4(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534100|imex:IM-18681-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492393.1|wormbase:F29D10.4|ensemblmetazoa:F29D10.4.1(transcript)|ensemblmetazoa:WBGene00002035(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR025660|interpro:IPR027417|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|dip:DIP-24485N|uniprotkb:Q17382(identity)|wormbase:WBGene00002035(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 118|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:COaNIVxftB8ggxM7ESkx2eOU3Q06239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:67C00AC12AB46016|rigid:maITphDLK74Nk9OiBw2135skfNc false sufficient binding region:1047-1100 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O18218 uniprotkb:Q19901 intact:EBI-2429037|uniprotkb:O18217|ensemblmetazoa:Y53C12B.3a.1|ensemblmetazoa:Y53C12B.3a.2 intact:EBI-326658|ensemblmetazoa:F29D10.4.1 psi-mi:o18218_caeel(display_long)|uniprotkb:nos-3(gene name)|psi-mi:nos-3(display_short)|uniprotkb:CELE_Y53C12B.3(orf name)|uniprotkb:Y53C12B.3(orf name) psi-mi:q19901_caeel(display_long)|uniprotkb:hum-1(gene name)|psi-mi:hum-1(display_short)|uniprotkb:CELE_F29D10.4(orf name)|uniprotkb:F29D10.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534115|imex:IM-18681-234 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496102.1|wormbase:Y53C12B.3a|dip:DIP-26678N|ensemblmetazoa:WBGene00003785(gene)|ensemblmetazoa:Y53C12B.3a.1(transcript)|ensemblmetazoa:Y53C12B.3a.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|interpro:IPR024161|interpro:IPR038129|uniprotkb:O18218(identity)|wormbase:WBGene00003785(identity) refseq:NP_492393.1|wormbase:F29D10.4|ensemblmetazoa:F29D10.4.1(transcript)|ensemblmetazoa:WBGene00002035(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR025660|interpro:IPR027417|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|dip:DIP-24485N|uniprotkb:Q17382(identity)|wormbase:WBGene00002035(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:XPPh+BPm8Kf/DvBBydou2aG/brA6239 rogid:COaNIVxftB8ggxM7ESkx2eOU3Q06239 intact-crc:A6DAA044F519EC39|rigid:aDYWoy1+uW8fs8uIewdxJXL8Sq0 false - sufficient binding region:1047-1100 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:Q18426 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-316187|ensemblmetazoa:C34C6.6a.1 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:q18426_caeel(display_long)|uniprotkb:prx-5(gene name)|psi-mi:prx-5(display_short)|uniprotkb:CELE_C34C6.6(orf name)|uniprotkb:C34C6.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534177|imex:IM-18681-238 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) refseq:NP_001022019.1|wormbase:C34C6.6a|ensemblmetazoa:C34C6.6a.1(transcript)|ensemblmetazoa:WBGene00004194(gene)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0002119"(nematode larval development)|go:"GO:0005052"(peroxisome matrix targeting signal-1 binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR024111|reactome:R-CEL-9033241|dip:DIP-25678N|reactome:R-CEL-8866654|uniprotkb:Q18426(identity)|wormbase:WBGene00004194(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:Nvy/XtOzTeJz6x3QzA44G3lm+Io6239 intact-crc:00E80B4F74E4A53C|rigid:RxY0M+KntrEcxXXKH7jy68gJbOs false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:G5ECD7 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-321964|ensemblmetazoa:C06C3.1c.1 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:g5ecd7_caeel(display_long)|uniprotkb:mel-11(gene name)|psi-mi:mel-11(display_short)|uniprotkb:C06C3.1(orf name)|uniprotkb:CELE_C06C3.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534147|imex:IM-18681-236 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) reactome:R-CEL-2565942|reactome:R-CEL-5627123|wormbase:C06C3.1c|uniprotkb:Q8I0N9(uniprot-removed-ac)|interpro:IPR031775|interpro:IPR002110(Ankyrin)|interpro:IPR020683|refseq:NP_001021928.1|ensemblmetazoa:C06C3.1c.1(transcript)|ensemblmetazoa:WBGene00003196(gene)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0048598"(embryonic morphogenesis)|reactome:R-CEL-5625740|interpro:IPR036770|uniprotkb:G5ECD7(identity)|wormbase:WBGene00003196(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:bGFxgXOiEstHHLok9wqg0GnsMJU6239 intact-crc:3DBBACE4BF15A9C6|rigid:StSnlbwdfkRiWrLf8Xa2yybpi0k false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:Q19951 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534162|imex:IM-18681-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:EC24AB681250184D|rigid:dkTQ6n8o1lw38TTdtkvH51OdXA8 false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:E3W743 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534224|imex:IM-18681-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 intact-crc:1533976EC83FD586|rigid:+jQaJo/eZUeHInZzFx+h4TvYrw0 false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:Q18605 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-331810|ensemblmetazoa:C44B9.4.1 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:q18605_caeel(display_long)|uniprotkb:athp-1(gene name)|psi-mi:athp-1(display_short)|uniprotkb:CELE_C44B9.4(orf name)|uniprotkb:C44B9.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534192|imex:IM-18681-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) refseq:NP_499397.2|wormbase:C44B9.4|dip:DIP-27259N|ensemblmetazoa:C44B9.4.1(transcript)|ensemblmetazoa:WBGene00008081(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR042163|uniprotkb:Q18605(identity)|wormbase:WBGene00008081(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:H5ZuRoDCv1AIMpTM9EehO/NyVd86239 intact-crc:61BE87862A6C226F|rigid:adQnAlxyVv0MvVTs2Q30gTs0yDc false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:B3GWA0 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-6534207|ensemblmetazoa:F25B5.7c.1 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:b3gwa0_caeel(display_long)|uniprotkb:nono-1(gene name)|psi-mi:nono-1(display_short)|uniprotkb:CELE_F25B5.7(orf name)|uniprotkb:F25B5.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534209|imex:IM-18681-240 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) ensemblmetazoa:F25B5.7c.1(transcript)|ensemblmetazoa:WBGene00017778(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR012975(NOPS)|refseq:NP_498296.3|wormbase:F25B5.7c|uniprotkb:B3GWA0(identity)|wormbase:WBGene00017778(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:lWJ7KO5EiJ5HtKHW+fGsAOn5RhU6239 intact-crc:A0A2960648AF9545|rigid:PO5JIChdBi0x8OYD1d5kFNTXFX8 false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21747 uniprotkb:Q19951 intact:EBI-324374|ensemblmetazoa:R05F9.1b.1|ensemblmetazoa:R05F9.1b.2 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:q21747_caeel(display_long)|uniprotkb:btbd-10(gene name)|psi-mi:btbd-10(display_short)|uniprotkb:snpc-1.4(gene name synonym)|uniprotkb:CELE_R05F9.1(orf name)|uniprotkb:R05F9.1(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534269|imex:IM-18681-244 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_740981.1|wormbase:R05F9.1b|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR039885|interpro:IPR039886|ensemblmetazoa:R05F9.1b.1(transcript)|ensemblmetazoa:R05F9.1b.2(transcript)|ensemblmetazoa:WBGene00019888(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0042327"(positive regulation of phosphorylation)|uniprotkb:Q21747(identity)|wormbase:WBGene00019888(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qXxgPBZ73WKhACkMLgbuhQ0ksrM6239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:38092E67116B3ECD|rigid:Yy5bENeQ6gWZQyPbwbw8ULvr8xc false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20010 uniprotkb:Q19951 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534239|imex:IM-18681-242 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N|uniprotkb:Q20010(identity)|wormbase:WBGene00009385(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:56787DDFDF11556F|rigid:0dtLkuqmHAQdrL7ekxPp9wQq8S4 false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:O01900 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534254|imex:IM-18681-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 15|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 intact-crc:CE0DABB66FE2D2F6|rigid:e5ymCunVKyT1esIpRRoTwb6x/9Y false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34552 uniprotkb:Q19951 intact:EBI-322767|uniprotkb:Q7YXC7|uniprotkb:Q8I114|uniprotkb:Q8I115|uniprotkb:Q94159|ensemblmetazoa:R10E12.1b.1|ensemblmetazoa:R10E12.1b.2 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:alxa_caeel(display_long)|uniprotkb:alx-1(gene name)|psi-mi:alx-1(display_short)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 58"(gene name synonym)|uniprotkb:Protein YNK1(gene name synonym)|uniprotkb:pqn-58(gene name synonym)|uniprotkb:R10E12.1(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534284|imex:IM-18681-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022713.1|refseq:NP_001022714.1|refseq:NP_001022715.1|refseq:NP_499213.1|wormbase:R10E12.1a|wormbase:R10E12.1b|wormbase:R10E12.1c|wormbase:R10E12.1d|interpro:IPR004328(BRO1)|interpro:IPR025304|ensemblmetazoa:R10E12.1b.1(transcript)|ensemblmetazoa:R10E12.1b.2(transcript)|ensemblmetazoa:WBGene00007010(gene)|go:"GO:0005112"(Notch binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0007032"(endosome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043226"(organelle)|go:"GO:0055037"(recycling endosome)|interpro:IPR038499|uniprotkb:P34552(identity)|wormbase:WBGene00007010(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:xedXAHU8Ms6VcKj1w9YZDHURHHg6239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:6362A09A157D0356|rigid:0n6vKd7t2bJ94mEDA4mpnVxjBfY false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:Q22631 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-312663|ensemblmetazoa:T21B6.3.1 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:q22631_caeel(display_long)|uniprotkb:T21B6.3(orf name)|uniprotkb:CELE_T21B6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534299|imex:IM-18681-246 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) refseq:NP_509829.2|wormbase:T21B6.3|ensemblmetazoa:T21B6.3.1(transcript)|ensemblmetazoa:WBGene00011880(gene)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR003609(Apple-like)|interpro:IPR036383|dip:DIP-24494N|uniprotkb:Q22631(identity)|wormbase:WBGene00011880(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:shfOWwt8+Ciel8Pd2b+UP69q1eI6239 intact-crc:CDDBA3C433B3C5A9|rigid:u8yvyY12nDbnseNjxAe28zirozI false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N490 uniprotkb:Q19951 intact:EBI-2316362|ensemblmetazoa:Y110A2AR.2a.1 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:q9n490_caeel(display_long)|uniprotkb:ubc-15(gene name)|psi-mi:ubc-15(display_short)|uniprotkb:CELE_Y110A2AR.2(orf name)|uniprotkb:Y110A2AR.2(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534346|imex:IM-18681-249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y110A2AR.2a|refseq:NP_494397.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|ensemblmetazoa:WBGene00006710(gene)|ensemblmetazoa:Y110A2AR.2a.1(transcript)|go:"GO:0031625"(ubiquitin protein ligase binding)|uniprotkb:Q9N490(identity)|wormbase:WBGene00006710(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:AD/8DQEwt8jeIhW+sRDlvEZGyPs6239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:800BB97633579026|rigid:n3zy1u2A7IFgIGj8nKGqpxnm46s false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:P91820 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534314|imex:IM-18681-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N|uniprotkb:P91820(identity)|wormbase:WBGene00003083(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 52|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 intact-crc:96C7D557DE3ECB81|rigid:nd9/v5TpeaTqMnxMdVisoZHUhe0 false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6534333 uniprotkb:Q19951 - intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:q965y4_caeel(display_short)|psi-mi:EBI-6534333(display_long)|uniprotkb:Y110A2AM.1(gene name)|psi-mi:Y110A2AM.1(display_short)|uniprotkb:CELE_Y110A2AM.1(orf name)|uniprotkb:Y110A2AM.1(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534329|imex:IM-18681-248 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q965Y4(uniprot-removed-ac)|uniprotkb:Q965Y4(identity)|wormbase:WBGene00022449(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zqy/LYo1vjSCTC0G4hp+sZ4vti06239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:E672DFA93100A092|rigid:NCPoJxBq7cQs+bFUkNq/CHJs4TY false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:Q8IAA7 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-326917|ensemblmetazoa:Y43H11AL.1a.1|ensemblmetazoa:Y43H11AL.1a.2|ensemblmetazoa:Y43H11AL.1a.3 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:q8iaa7_caeel(display_long)|uniprotkb:CELE_Y43H11AL.1(orf name)|uniprotkb:Y43H11AL.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534361|imex:IM-18681-250 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) wormbase:Y43H11AL.1a|refseq:NP_001254008.1|ensemblmetazoa:WBGene00021545(gene)|ensemblmetazoa:Y43H11AL.1a.1(transcript)|ensemblmetazoa:Y43H11AL.1a.2(transcript)|ensemblmetazoa:Y43H11AL.1a.3(transcript)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR028651|dip:DIP-25986N|uniprotkb:Q8IAA7(identity)|wormbase:WBGene00021545(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:uxIfUO3WtbnO6LpXcFhjoa2U0fI6239 intact-crc:D1A33EE58BE6A0E8|rigid:wTU/CNdVh19rO7vwHiHov/xXx/Y false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:G5EC32 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534376|imex:IM-18681-251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:B573B5C3630DB80A|rigid:U5m+QRTF4ZzZR0Y5LmKNOjeD2Sw false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A5PEX6 uniprotkb:Q19951 intact:EBI-6532321|ensemblmetazoa:Y57A10A.18b.1|ensemblmetazoa:Y57A10A.18b.2 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:a5pex6_caeel(display_long)|uniprotkb:Y57A10A.18(orf name)|uniprotkb:pqn-87(gene name)|psi-mi:pqn-87(display_short)|uniprotkb:CELE_Y57A10A.18(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534393|imex:IM-18681-252 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004167(gene)|ensemblmetazoa:Y57A10A.18b.1(transcript)|ensemblmetazoa:Y57A10A.18b.2(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|refseq:NP_001122665.1|wormbase:Y57A10A.18b|uniprotkb:A5PEX6(identity)|wormbase:WBGene00004167(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:U79ecDJtHc4bqHRcr6eBglpyv5k6239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:FA089F01752906BE|rigid:/9ltO/kiWCoyB64HOLTZXHKM02k false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBP4 uniprotkb:Q20005 intact:EBI-6533123|ensemblmetazoa:ZK270.2e.1 intact:EBI-2915449|ensemblmetazoa:F35A5.8a.1 psi-mi:g5ebp4_caeel(display_long)|uniprotkb:ZK270.2(orf name)|uniprotkb:frm-1(gene name)|psi-mi:frm-1(display_short)|uniprotkb:CELE_ZK270.2(orf name) psi-mi:q20005_caeel(display_long)|uniprotkb:F35A5.8(orf name)|uniprotkb:CELE_F35A5.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534440|imex:IM-18681-255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00001488(gene)|ensemblmetazoa:ZK270.2e.1(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0031032"(actomyosin structure organization)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|refseq:NP_001021866.1|wormbase:ZK270.2e|interpro:IPR029071|interpro:IPR035963|uniprotkb:G5EBP4(identity)|wormbase:WBGene00001488(identity) ensemblmetazoa:F35A5.8a.1(transcript)|ensemblmetazoa:WBGene00001335(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR027267|refseq:NP_741756.1|wormbase:F35A5.8a|interpro:IPR004148(BAR)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:Q20005(identity)|wormbase:WBGene00001335(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:icCNtsa9axw3hWuvhmT4WH+2pAQ6239 rogid:HwODK9IV3CjSSkfAa0vHHfzI1MM6239 intact-crc:CC049678AECA31A6|rigid:K5QiX6AnDk6yKj62pzliiOwA0Xo false - sufficient binding region:310-366 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:G5ED33 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534408|imex:IM-18681-253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 28|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:B7B929CDD940FC65|rigid:GGMPlf/i5S1fJVec0YQYi9D5IZk false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7K705 uniprotkb:Q19951 intact:EBI-6534423|ensemblmetazoa:Y79H2A.3b.1 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:q7k705_caeel(display_long)|uniprotkb:CELE_Y79H2A.3(orf name)|uniprotkb:Y79H2A.3(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534425|imex:IM-18681-254 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00013580(gene)|ensemblmetazoa:Y79H2A.3b.1(transcript)|refseq:NP_001022956.2|wormbase:Y79H2A.3b|uniprotkb:Q7K705(identity)|wormbase:WBGene00013580(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:019BBGCwtZ7E1FIsBbmMSZl+WKE6239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:EE281669517E70E2|rigid:lXYTgfguBaP8FIQp5uZhE63ufsU false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWR1 uniprotkb:Q94222 intact:EBI-2002612|intact:EBI-6534487|uniprotkb:A7DTF1|uniprotkb:D3NQA3|ensemblmetazoa:Y11D7A.12a.1 intact:EBI-6534455|ensemblmetazoa:F41D9.1.1 psi-mi:flh1_caeel(display_long)|uniprotkb:flh-1(gene name)|psi-mi:flh-1(display_short)|uniprotkb:Y11D7A.12(orf name) psi-mi:q94222_caeel(display_long)|uniprotkb:F41D9.1(orf name)|uniprotkb:tbc-18(gene name)|psi-mi:tbc-18(display_short)|uniprotkb:CELE_F41D9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534489|imex:IM-18681-258 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501618.2|wormbase:Y11D7A.12a|wormbase:Y11D7A.12b|wormbase:Y11D7A.12c|dip:DIP-24849N|ensemblmetazoa:WBGene00012435(gene)|ensemblmetazoa:Y11D7A.12a.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR007588(Zinc finger, FLYWCH-type)|uniprotkb:A7DTF1(identity)|wormbase:WBGene00012435(identity) ensemblmetazoa:F41D9.1.1(transcript)|ensemblmetazoa:WBGene00018281(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR035833|interpro:IPR000195(RabGAP/TBC)|interpro:IPR001452(Src homology-3)|interpro:IPR004012(RUN)|refseq:NP_509421.2|wormbase:F41D9.1|interpro:IPR035969|interpro:IPR036028|interpro:IPR037213|uniprotkb:Q94222(identity)|wormbase:WBGene00018281(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2021/11/30 rogid:BUwEONwxmU5dE1HyJh2inla8obA6239 rogid:ftXmjV0D2pNfj99fNaLg290vCRg6239 intact-crc:3CEA40DBC46AB95F|rigid:JCBxDsoGLMkNFk6lvMBVlt4QjuI false - sufficient binding region:527-582 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q94222 uniprotkb:P20271 intact:EBI-6534455|ensemblmetazoa:F41D9.1.1 intact:EBI-2411837|uniprotkb:Q9NBV6|ensemblmetazoa:F46C8.5.1 psi-mi:q94222_caeel(display_long)|uniprotkb:F41D9.1(orf name)|uniprotkb:tbc-18(gene name)|psi-mi:tbc-18(display_short)|uniprotkb:CELE_F41D9.1(orf name) psi-mi:hm14_caeel(display_long)|uniprotkb:F46C8.5(orf name)|uniprotkb:ceh-14(gene name)|psi-mi:ceh-14(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534457|imex:IM-18681-256 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F41D9.1.1(transcript)|ensemblmetazoa:WBGene00018281(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR035833|interpro:IPR000195(RabGAP/TBC)|interpro:IPR001452(Src homology-3)|interpro:IPR004012(RUN)|refseq:NP_509421.2|wormbase:F41D9.1|interpro:IPR035969|interpro:IPR036028|interpro:IPR037213|uniprotkb:Q94222(identity)|wormbase:WBGene00018281(identity) refseq:NP_509273.1|wormbase:F46C8.5|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|interpro:IPR001781(Zinc finger, LIM-type)|ensemblmetazoa:F46C8.5.1(transcript)|ensemblmetazoa:WBGene00000438(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030182"(neuron differentiation)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048666"(neuron development)|uniprotkb:P20271(identity)|wormbase:WBGene00000438(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ftXmjV0D2pNfj99fNaLg290vCRg6239 rogid:fmXWGXQZGrTRlVC7uS0ca3SR3C46239 intact-crc:9FEABA8C5D2150DF|rigid:DqDqN3L0w/pPqfVgER3X3o5yvUg false sufficient binding region:527-582 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21502 uniprotkb:Q94222 intact:EBI-319858|uniprotkb:Q95VF1|ensemblmetazoa:M04B2.1.1 intact:EBI-6534455|ensemblmetazoa:F41D9.1.1 psi-mi:mep1_caeel(display_long)|uniprotkb:M04B2.1(orf name)|uniprotkb:Nuclear zinc finger protein(gene name synonym)|uniprotkb:mep-1(gene name)|psi-mi:mep-1(display_short) psi-mi:q94222_caeel(display_long)|uniprotkb:F41D9.1(orf name)|uniprotkb:tbc-18(gene name)|psi-mi:tbc-18(display_short)|uniprotkb:CELE_F41D9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534472|imex:IM-18681-257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502173.2|wormbase:M04B2.1|ensemblmetazoa:M04B2.1.1(transcript)|ensemblmetazoa:WBGene00003218(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008406"(gonad development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0040025"(vulval development)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048599"(oocyte development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|uniprotkb:Q21502(identity)|wormbase:WBGene00003218(identity) ensemblmetazoa:F41D9.1.1(transcript)|ensemblmetazoa:WBGene00018281(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR035833|interpro:IPR000195(RabGAP/TBC)|interpro:IPR001452(Src homology-3)|interpro:IPR004012(RUN)|refseq:NP_509421.2|wormbase:F41D9.1|interpro:IPR035969|interpro:IPR036028|interpro:IPR037213|uniprotkb:Q94222(identity)|wormbase:WBGene00018281(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:5BfQpmdZPLVYpnz8eRO3Ubzxqbg6239 rogid:ftXmjV0D2pNfj99fNaLg290vCRg6239 intact-crc:BB1F43CD818BB22A|rigid:3vqFsANxIJMSkjyPS9ftCuFvBZ0 false - sufficient binding region:527-582 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20010 uniprotkb:P34416 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534536|imex:IM-18681-261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N|uniprotkb:Q20010(identity)|wormbase:WBGene00009385(identity) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 intact-crc:0429134B26BB1ECB|rigid:a5YzTw3cVWAnL+J+DW1ZL8jsSN8 false - sufficient binding region:269-326 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10956 uniprotkb:P34416 intact:EBI-6534508|ensemblmetazoa:B0336.11a.1 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 psi-mi:q10956_caeel(display_long)|uniprotkb:CELE_B0336.11(orf name)|uniprotkb:hpo-28(gene name)|psi-mi:hpo-28(display_short)|uniprotkb:B0336.11(orf name) psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534504|imex:IM-18681-259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:B0336.11a.1(transcript)|ensemblmetazoa:WBGene00015148(gene)|go:"GO:0016021"(integral component of membrane)|interpro:IPR013783(Immunoglobulin-like fold)|reactome:R-CEL-9013405|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|refseq:NP_498232.3|wormbase:B0336.11a|interpro:IPR036273|interpro:IPR036865|uniprotkb:Q10956(identity)|wormbase:WBGene00015148(identity) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:XmcWjzXtZlng2eZf3MXQuh+dfzI6239 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 intact-crc:B2128CED7A98638A|rigid:KGGSy2iutY5El/ttFmCLPBcaAKI false - sufficient binding region:269-326 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34416 uniprotkb:Q10958 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 intact:EBI-6455901|ensemblmetazoa:B0353.1a.1 psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:yt31_caeel(display_long)|uniprotkb:B0353.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534521|imex:IM-18681-260 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) ensemblmetazoa:B0353.1a.1(transcript)|ensemblmetazoa:WBGene00015155(gene)|refseq:NP_497210.1|wormbase:B0353.1a|uniprotkb:Q10958(identity)|wormbase:WBGene00015155(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 46|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 rogid:VCgUbqnsBVsBTT1q7xZcvyXVk1Y6239 intact-crc:CF3EBCDE32ABEC64|rigid:9wezey/fOvLmY/yEMDlzQOtgqMM false sufficient binding region:269-326 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34416 uniprotkb:Q6A573 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534585|imex:IM-18681-264 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:5A82A8541C0C8A91|rigid:aP0p1gilV5JtPbKohLI08t2Zk/Q false sufficient binding region:269-326 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17905 uniprotkb:P34416 intact:EBI-6534551|ensemblmetazoa:H05G16.1a.1 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 psi-mi:o17905_caeel(display_long)|uniprotkb:H05G16.1(orf name)|uniprotkb:frm-3(gene name)|psi-mi:frm-3(display_short)|uniprotkb:CELE_H05G16.1(orf name) psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534553|imex:IM-18681-262 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-399955|wormbase:H05G16.1a|ensemblmetazoa:H05G16.1a.1(transcript)|ensemblmetazoa:WBGene00001490(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9035034|reactome:R-CEL-8980692|interpro:IPR000299(Band 4.1, N-terminal)|refseq:NP_509934.2|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041788|uniprotkb:O17905(identity)|wormbase:WBGene00001490(identity) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DqAi5bwjB+PKV7pDJe28/eBDS6Y6239 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 intact-crc:F7A5E6AF5A8C3AD2|rigid:V0jbzoCa4j9dYI13KvPsvYjnLS8 false - sufficient binding region:269-326 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34416 uniprotkb:Q7JP60 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 intact:EBI-6534568|ensemblmetazoa:R08E3.3b.1 psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:q7jp60_caeel(display_long)|uniprotkb:CELE_R08E3.3(orf name)|uniprotkb:R08E3.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534570|imex:IM-18681-263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) ensemblmetazoa:R08E3.3b.1(transcript)|ensemblmetazoa:WBGene00019959(gene)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|refseq:NP_001024849.1|wormbase:R08E3.3b|reactome:R-CEL-8951664|uniprotkb:Q7JP60(identity)|wormbase:WBGene00019959(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 rogid:HfBZf7yrrXcSNeQmWUPq7B2XOCk6239 intact-crc:BDC08D778A5016E9|rigid:jm3KR8Yr+3DRe/+RCsm4PPvEE3I false sufficient binding region:269-326 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N391 uniprotkb:P34416 intact:EBI-6534604|ensemblmetazoa:B0353.1e.1|ensemblmetazoa:B0353.1e.2 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 psi-mi:q9n391_caeel(display_long)|uniprotkb:B0353.1(orf name)|uniprotkb:CELE_B0353.1(orf name) psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534600|imex:IM-18681-265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:B0353.1e.1(transcript)|ensemblmetazoa:B0353.1e.2(transcript)|ensemblmetazoa:WBGene00015155(gene)|wormbase:B0353.1e|refseq:NP_497211.1|uniprotkb:Q9N391(identity)|wormbase:WBGene00021903(identity) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:HhI5rfkjyI1HbDMfObC3ynnwdTg6239 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 intact-crc:45306F1C23A1E3E4|rigid:XqWbDv2ChpcqmbUUzSBvtTXdl/I false - sufficient binding region:269-326 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:P34416 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534617|imex:IM-18681-266 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 intact-crc:39F2D367377B2EBA|rigid:Kp1MLO2TX16IX6XLlm+6XJ0XO6E false - sufficient binding region:269-326 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16299 uniprotkb:Q09989 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534662|imex:IM-18681-269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 39|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:0B9A412E305A6EE4|rigid:H1AfBxM8oqL3Hf6nljNtF6Bi9wM false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19275 uniprotkb:Q09989 intact:EBI-315168|ensemblmetazoa:F09F7.5a.1|ensemblmetazoa:F09F7.5a.2|ensemblmetazoa:F09F7.5a.3 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:q19275_caeel(display_long)|uniprotkb:CELE_F09F7.5(orf name)|uniprotkb:F09F7.5(orf name) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534632|imex:IM-18681-267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498186.1|wormbase:F09F7.5a|go:"GO:0005886"(plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035023"(regulation of Rho protein signal transduction)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR036936|interpro:IPR039056|ensemblmetazoa:WBGene00017302(gene)|ensemblmetazoa:F09F7.5a.1(transcript)|ensemblmetazoa:F09F7.5a.2(transcript)|ensemblmetazoa:F09F7.5a.3(transcript)|dip:DIP-25885N|uniprotkb:Q19275(identity)|wormbase:WBGene00017302(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 124|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:dRcTzChc6E57GiyrC46iYMLP5Tg6239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:D2E3D6BC13EFA9F8|rigid:pqCHEq8VWRZL/4zY4GuyomJNNEc false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 uniprotkb:B3GWA0 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 intact:EBI-6534207|ensemblmetazoa:F25B5.7c.1 psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:b3gwa0_caeel(display_long)|uniprotkb:nono-1(gene name)|psi-mi:nono-1(display_short)|uniprotkb:CELE_F25B5.7(orf name)|uniprotkb:F25B5.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534647|imex:IM-18681-268 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) ensemblmetazoa:F25B5.7c.1(transcript)|ensemblmetazoa:WBGene00017778(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR012975(NOPS)|refseq:NP_498296.3|wormbase:F25B5.7c|uniprotkb:B3GWA0(identity)|wormbase:WBGene00017778(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:lWJ7KO5EiJ5HtKHW+fGsAOn5RhU6239 intact-crc:298C8C83C93CFB6A|rigid:qHUdMb4XToK2vl7Men/zHQthh/c false sufficient binding region:430-486 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 uniprotkb:Q21225 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 intact:EBI-314174|ensemblmetazoa:K04G2.6.1 psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:q21225_caeel(display_long)|uniprotkb:vacl-14(gene name)|psi-mi:vacl-14(display_short)|uniprotkb:K04G2.6(orf name)|uniprotkb:CELE_K04G2.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534709|imex:IM-18681-272 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) refseq:NP_492215.1|wormbase:K04G2.6|ensemblmetazoa:K04G2.6.1(transcript)|ensemblmetazoa:WBGene00010565(gene)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0070772"(PAS complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|dip:DIP-24602N|uniprotkb:Q21225(identity)|wormbase:WBGene00010565(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:MeQDLdLkRT0gm1ctftVBr4XIUiA6239 intact-crc:72778FB792F49B14|rigid:FRq8yg+HUSx8n+IBdHF/ePUus70 false sufficient binding region:430-486 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:C7IVR4 uniprotkb:Q09989 intact:EBI-6530632|ensemblmetazoa:F53A3.4b.1|intact:EBI-6534681|uniprotkb:C7IVR5|uniprotkb:C7IVR6|uniprotkb:G4RT57|uniprotkb:G4RT58|uniprotkb:S6FMX9|uniprotkb:G4RT56 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:pqn41_caeel(display_long)|uniprotkb:pqn-41(gene name)|psi-mi:pqn-41(display_short)|uniprotkb:"Prion-like-(Q/N-rich)-domain-bearing protein 41"(gene name synonym)|uniprotkb:F53A3.4(orf name) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534677|imex:IM-18681-270 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F53A3.4b.1(transcript)|ensemblmetazoa:WBGene00004128(gene)|go:"GO:0005737"(cytoplasm)|refseq:NP_001254849.1|refseq:NP_001293605.1|refseq:NP_497478.2|refseq:NP_001122699.2|wormbase:F53A3.4a|wormbase:F53A3.4b|wormbase:F53A3.4d|wormbase:F53A3.4c|uniprotkb:C7IVR4(identity)|wormbase:WBGene00004128(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/07/27 rogid:4TZHkc+tLknBLkttfphB00oNkd06239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:AE13232E0A33F30F|rigid:huXIqpv7WGszNa6CuGr9VOPpLn8 false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O77469 uniprotkb:Q09989 intact:EBI-321052|uniprotkb:Q50JF9|uniprotkb:Q5I5Q9|uniprotkb:O18026|uniprotkb:O77474|uniprotkb:Q20903|uniprotkb:Q95NZ3|uniprotkb:Q9TZS1|ensemblmetazoa:F56H11.1c.1 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:fbln1_caeel(display_long)|uniprotkb:F56H11.1(orf name)|uniprotkb:fbl-1(gene name)|psi-mi:fbl-1(display_short)|uniprotkb:fbln1(gene name synonym) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534694|imex:IM-18681-271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023236.1|refseq:NP_001023237.1|refseq:NP_501694.2|wormbase:F56H11.1a|wormbase:F56H11.1b|wormbase:F56H11.1c|ensemblmetazoa:F56H11.1c.1(transcript)|ensemblmetazoa:WBGene00001403(gene)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0008104"(protein localization)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0040017"(positive regulation of locomotion)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR017048(Fibulin-1)|interpro:IPR018097|interpro:IPR026823|dip:DIP-26629N|uniprotkb:O77469(identity)|wormbase:WBGene00001403(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Lw7QPEDcS+u0cxNDZB52AmTXFE86239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:2BC6C17CF8C3F9B9|rigid:OHkRt4avZP35r4d7dr6Ffvd0CxU false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 intact:EBI-6534333 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 - psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:q965y4_caeel(display_short)|psi-mi:EBI-6534333(display_long)|uniprotkb:Y110A2AM.1(gene name)|psi-mi:Y110A2AM.1(display_short)|uniprotkb:CELE_Y110A2AM.1(orf name)|uniprotkb:Y110A2AM.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534754|imex:IM-18681-275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) uniprotkb:Q965Y4(uniprot-removed-ac)|uniprotkb:Q965Y4(identity)|wormbase:WBGene00022449(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:zqy/LYo1vjSCTC0G4hp+sZ4vti06239 intact-crc:26BAE38B464443A3|rigid:6KKNRp8pMUMzhspb3wsUryD5DKs false sufficient binding region:430-486 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 uniprotkb:O45797 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 intact:EBI-317435|ensemblmetazoa:T20F10.1.1 psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:warts_caeel(display_long)|uniprotkb:LATS kinase homolog(gene name synonym)|uniprotkb:T20F10.1(orf name)|uniprotkb:wts-1(gene name)|psi-mi:wts-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534724|imex:IM-18681-273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) reactome:R-CEL-2028269|refseq:NP_492699.1|wormbase:T20F10.1|ensemblmetazoa:T20F10.1.1(transcript)|ensemblmetazoa:WBGene00007047(gene)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002119"(nematode larval development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030421"(defecation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045176"(apical protein localization)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048621"(post-embryonic digestive tract morphogenesis)|go:"GO:0060465"(pharynx development)|go:"GO:0061067"(negative regulation of dauer larval development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028742|dip:DIP-26953N|uniprotkb:O45797(identity)|wormbase:WBGene00007047(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:QoC2FtrGdcw7T2ruGNvLPwYj3XE6239 intact-crc:0F3E499B1C5EE4EA|rigid:UIVdD4HoT2rnRDr08WaWzGbxsxk false sufficient binding region:430-486 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91820 uniprotkb:Q09989 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534739|imex:IM-18681-274 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N|uniprotkb:P91820(identity)|wormbase:WBGene00003083(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:958B72E932982999|rigid:sAWfHBq91KzEFErYbjrjDokhv70 false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93203 uniprotkb:Q9XVN3 intact:EBI-315294|ensemblmetazoa:C11E4.6.1 intact:EBI-6534803|ensemblmetazoa:F46F3.4a.1|uniprotkb:E0AHC9|uniprotkb:E0AHD0|uniprotkb:E0AHD1 psi-mi:q93203_caeel(display_long)|uniprotkb:C11E4.6(orf name)|uniprotkb:CELE_C11E4.6(orf name) psi-mi:iaspp_caeel(display_long)|uniprotkb:ape-1(gene name)|psi-mi:ape-1(display_short)|uniprotkb:Ce-iASPP(gene name synonym)|uniprotkb:Inhibitor member of the ASPP family(gene name synonym)|uniprotkb:F46F3.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534799|imex:IM-18681-278 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509620.2|wormbase:C11E4.6|ensemblmetazoa:C11E4.6.1(transcript)|ensemblmetazoa:WBGene00007520(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|dip:DIP-25879N|uniprotkb:Q93203(identity)|wormbase:WBGene00007520(identity) ensemblmetazoa:F46F3.4a.1(transcript)|ensemblmetazoa:WBGene00000146(gene)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:NP_001256353.1|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|wormbase:F46F3.4a|interpro:IPR036028|interpro:IPR036770|refseq:NP_001256354.1|refseq:NP_001256355.1|refseq:NP_001256356.1|wormbase:F46F3.4b|wormbase:F46F3.4c|wormbase:F46F3.4d|uniprotkb:Q9XVN3(identity)|wormbase:WBGene00000146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 24|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4lnus3cgxAI4dQDe0XjYAgmH2us6239 rogid:Y7YswK3q0/HwOelbHJOIgFi08AA6239 intact-crc:5349EC6DE50064C2|rigid:K0EfR4CrUc0L3Rnw7QIiJDeuGgA false - sufficient binding region:687-745 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XQ1 uniprotkb:Q09989 intact:EBI-313459|ensemblmetazoa:Y39G10AR.17.1 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:sydn_caeel(display_long)|uniprotkb:Y39G10AR.17(orf name)|uniprotkb:sydn-1(gene name)|psi-mi:sydn-1(display_short) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534769|imex:IM-18681-276 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y39G10AR.17|ensemblmetazoa:WBGene00021473(gene)|ensemblmetazoa:Y39G10AR.17.1(transcript)|go:"GO:0016607"(nuclear speck)|go:"GO:0006397"(mRNA processing)|mint:Q95XQ1|refseq:NP_490969.4|dip:DIP-24383N|uniprotkb:Q95XQ1(identity)|wormbase:WBGene00021473(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:aoAMOcrfpjxDHg+8smQRjOT8yz46239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:DC6DA429FF02E3C7|rigid:nPhNdYGFAyeI7Z945do2/kIhvhY false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WTJ8 uniprotkb:Q09989 intact:EBI-321112|ensemblmetazoa:Y51F10.2a.1|ensemblmetazoa:Y51F10.2a.2 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:q8wtj8_caeel(display_long)|uniprotkb:Y51F10.2(orf name)|uniprotkb:CELE_Y51F10.2(orf name) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534784|imex:IM-18681-277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_740796.1|ensemblmetazoa:WBGene00021763(gene)|ensemblmetazoa:Y51F10.2a.1(transcript)|ensemblmetazoa:Y51F10.2a.2(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|wormbase:Y51F10.2a|dip:DIP-26335N|uniprotkb:Q8WTJ8(identity)|wormbase:WBGene00021763(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ecYf0rK4DGesDNxewp2Vg2bxK/Y6239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:8F8DC1AD2C5BE5F7|rigid:11c4r6SkHmCQfTRvipGLL4+HLa4 false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:V6CJ04 uniprotkb:Q9XVN3 intact:EBI-2006416|uniprotkb:V6CK55|ensemblmetazoa:C43G2.2a.1 intact:EBI-6534803|ensemblmetazoa:F46F3.4a.1|uniprotkb:E0AHC9|uniprotkb:E0AHD0|uniprotkb:E0AHD1 psi-mi:bicd_caeel(display_long)|uniprotkb:bicd-1(gene name)|psi-mi:bicd-1(display_short)|uniprotkb:C43G2.2(orf name) psi-mi:iaspp_caeel(display_long)|uniprotkb:ape-1(gene name)|psi-mi:ape-1(display_short)|uniprotkb:Ce-iASPP(gene name synonym)|uniprotkb:Inhibitor member of the ASPP family(gene name synonym)|uniprotkb:F46F3.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534816|imex:IM-18681-279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293734.1|reactome:R-CEL-6811436|refseq:NP_001293735.1|wormbase:C43G2.2a|interpro:IPR018477|wormbase:C43G2.2b|ensemblmetazoa:C43G2.2a.1(transcript)|ensemblmetazoa:WBGene00016611(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0030425"(dendrite)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034452"(dynactin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072393"(microtubule anchoring at microtubule organizing center)|uniprotkb:Q94174(identity)|wormbase:WBGene00016611(identity) ensemblmetazoa:F46F3.4a.1(transcript)|ensemblmetazoa:WBGene00000146(gene)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:NP_001256353.1|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|wormbase:F46F3.4a|interpro:IPR036028|interpro:IPR036770|refseq:NP_001256354.1|refseq:NP_001256355.1|refseq:NP_001256356.1|wormbase:F46F3.4b|wormbase:F46F3.4c|wormbase:F46F3.4d|uniprotkb:Q9XVN3(identity)|wormbase:WBGene00000146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GKxa/6aMKacxpHsFwY9PqHjwIBw6239 rogid:Y7YswK3q0/HwOelbHJOIgFi08AA6239 intact-crc:14E7360480C4A550|rigid:cNetJTaevWdfuP2cNhMewsi+UWE false - sufficient binding region:687-745 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19246 uniprotkb:Q9XVN3 intact:EBI-6532578|ensemblmetazoa:F09E10.3.1 intact:EBI-6534803|ensemblmetazoa:F46F3.4a.1|uniprotkb:E0AHC9|uniprotkb:E0AHD0|uniprotkb:E0AHD1 psi-mi:q19246_caeel(display_long)|uniprotkb:F09E10.3(orf name)|uniprotkb:dhs-25(gene name)|psi-mi:dhs-25(display_short)|uniprotkb:CELE_F09E10.3(orf name) psi-mi:iaspp_caeel(display_long)|uniprotkb:ape-1(gene name)|psi-mi:ape-1(display_short)|uniprotkb:Ce-iASPP(gene name synonym)|uniprotkb:Inhibitor member of the ASPP family(gene name synonym)|uniprotkb:F46F3.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534831|imex:IM-18681-280 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F09E10.3.1(transcript)|ensemblmetazoa:WBGene00000988(gene)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0048038"(quinone binding)|wormbase:F09E10.3|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|refseq:NP_508282.2|interpro:IPR036291|uniprotkb:Q19246(identity)|wormbase:WBGene00000988(identity) ensemblmetazoa:F46F3.4a.1(transcript)|ensemblmetazoa:WBGene00000146(gene)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:NP_001256353.1|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|wormbase:F46F3.4a|interpro:IPR036028|interpro:IPR036770|refseq:NP_001256354.1|refseq:NP_001256355.1|refseq:NP_001256356.1|wormbase:F46F3.4b|wormbase:F46F3.4c|wormbase:F46F3.4d|uniprotkb:Q9XVN3(identity)|wormbase:WBGene00000146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:/9OXoN4g7Wmomnj4Ui7NHZDn1T86239 rogid:Y7YswK3q0/HwOelbHJOIgFi08AA6239 intact-crc:7253AFB425AED080|rigid:Dhv9bQUfPenwmyR4BhJ6Jfg6d1U false - sufficient binding region:687-745 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVN3 uniprotkb:P34552 intact:EBI-6534803|ensemblmetazoa:F46F3.4a.1|uniprotkb:E0AHC9|uniprotkb:E0AHD0|uniprotkb:E0AHD1 intact:EBI-322767|uniprotkb:Q7YXC7|uniprotkb:Q8I114|uniprotkb:Q8I115|uniprotkb:Q94159|ensemblmetazoa:R10E12.1b.1|ensemblmetazoa:R10E12.1b.2 psi-mi:iaspp_caeel(display_long)|uniprotkb:ape-1(gene name)|psi-mi:ape-1(display_short)|uniprotkb:Ce-iASPP(gene name synonym)|uniprotkb:Inhibitor member of the ASPP family(gene name synonym)|uniprotkb:F46F3.4(orf name) psi-mi:alxa_caeel(display_long)|uniprotkb:alx-1(gene name)|psi-mi:alx-1(display_short)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 58"(gene name synonym)|uniprotkb:Protein YNK1(gene name synonym)|uniprotkb:pqn-58(gene name synonym)|uniprotkb:R10E12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534876|imex:IM-18681-283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F46F3.4a.1(transcript)|ensemblmetazoa:WBGene00000146(gene)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:NP_001256353.1|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|wormbase:F46F3.4a|interpro:IPR036028|interpro:IPR036770|refseq:NP_001256354.1|refseq:NP_001256355.1|refseq:NP_001256356.1|wormbase:F46F3.4b|wormbase:F46F3.4c|wormbase:F46F3.4d|uniprotkb:Q9XVN3(identity)|wormbase:WBGene00000146(identity) refseq:NP_001022713.1|refseq:NP_001022714.1|refseq:NP_001022715.1|refseq:NP_499213.1|wormbase:R10E12.1a|wormbase:R10E12.1b|wormbase:R10E12.1c|wormbase:R10E12.1d|interpro:IPR004328(BRO1)|interpro:IPR025304|ensemblmetazoa:R10E12.1b.1(transcript)|ensemblmetazoa:R10E12.1b.2(transcript)|ensemblmetazoa:WBGene00007010(gene)|go:"GO:0005112"(Notch binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0007032"(endosome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043226"(organelle)|go:"GO:0055037"(recycling endosome)|interpro:IPR038499|uniprotkb:P34552(identity)|wormbase:WBGene00007010(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 32|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Y7YswK3q0/HwOelbHJOIgFi08AA6239 rogid:xedXAHU8Ms6VcKj1w9YZDHURHHg6239 intact-crc:E1C54AE12FDB199A|rigid:ERXDN2KpuBEPQJF/z2VVrvl0ZOE false sufficient binding region:687-745 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16299 uniprotkb:Q9XVN3 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 intact:EBI-6534803|ensemblmetazoa:F46F3.4a.1|uniprotkb:E0AHC9|uniprotkb:E0AHD0|uniprotkb:E0AHD1 psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:iaspp_caeel(display_long)|uniprotkb:ape-1(gene name)|psi-mi:ape-1(display_short)|uniprotkb:Ce-iASPP(gene name synonym)|uniprotkb:Inhibitor member of the ASPP family(gene name synonym)|uniprotkb:F46F3.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534846|imex:IM-18681-281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) ensemblmetazoa:F46F3.4a.1(transcript)|ensemblmetazoa:WBGene00000146(gene)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:NP_001256353.1|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|wormbase:F46F3.4a|interpro:IPR036028|interpro:IPR036770|refseq:NP_001256354.1|refseq:NP_001256355.1|refseq:NP_001256356.1|wormbase:F46F3.4b|wormbase:F46F3.4c|wormbase:F46F3.4d|uniprotkb:Q9XVN3(identity)|wormbase:WBGene00000146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 43|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 rogid:Y7YswK3q0/HwOelbHJOIgFi08AA6239 intact-crc:3E6175BCD32C94B5|rigid:Y+mnbLZOBrUbnEKWin6cqpHll54 false - sufficient binding region:687-745 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20177 uniprotkb:Q9XVN3 intact:EBI-325747|ensemblmetazoa:F38E9.1.1 intact:EBI-6534803|ensemblmetazoa:F46F3.4a.1|uniprotkb:E0AHC9|uniprotkb:E0AHD0|uniprotkb:E0AHD1 psi-mi:q20177_caeel(display_long)|uniprotkb:F38E9.1(orf name)|uniprotkb:CELE_F38E9.1(orf name) psi-mi:iaspp_caeel(display_long)|uniprotkb:ape-1(gene name)|psi-mi:ape-1(display_short)|uniprotkb:Ce-iASPP(gene name synonym)|uniprotkb:Inhibitor member of the ASPP family(gene name synonym)|uniprotkb:F46F3.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534861|imex:IM-18681-282 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_510673.1|wormbase:F38E9.1|ensemblmetazoa:F38E9.1.1(transcript)|ensemblmetazoa:WBGene00018184(gene)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008081"(phosphoric diester hydrolase activity)|interpro:IPR017946|interpro:IPR042158|dip:DIP-25899N|uniprotkb:Q20177(identity)|wormbase:WBGene00018184(identity) ensemblmetazoa:F46F3.4a.1(transcript)|ensemblmetazoa:WBGene00000146(gene)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:NP_001256353.1|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|wormbase:F46F3.4a|interpro:IPR036028|interpro:IPR036770|refseq:NP_001256354.1|refseq:NP_001256355.1|refseq:NP_001256356.1|wormbase:F46F3.4b|wormbase:F46F3.4c|wormbase:F46F3.4d|uniprotkb:Q9XVN3(identity)|wormbase:WBGene00000146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:0365vrSc61A665R4aWQd0t/XHNA6239 rogid:Y7YswK3q0/HwOelbHJOIgFi08AA6239 intact-crc:0374793683B928B0|rigid:OPEjyXx/mDoojQMF1rq4xMpwIaA false - sufficient binding region:687-745 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45812 uniprotkb:Q9XVN3 intact:EBI-6534925|ensemblmetazoa:T23G11.7b.1 intact:EBI-6534803|ensemblmetazoa:F46F3.4a.1|uniprotkb:E0AHC9|uniprotkb:E0AHD0|uniprotkb:E0AHD1 psi-mi:o45812_caeel(display_long)|uniprotkb:CELE_T23G11.7(orf name)|uniprotkb:T23G11.7(orf name) psi-mi:iaspp_caeel(display_long)|uniprotkb:ape-1(gene name)|psi-mi:ape-1(display_short)|uniprotkb:Ce-iASPP(gene name synonym)|uniprotkb:Inhibitor member of the ASPP family(gene name synonym)|uniprotkb:F46F3.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534921|imex:IM-18681-286 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T23G11.7b.1(transcript)|ensemblmetazoa:WBGene00011972(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0035493"(SNARE complex assembly)|interpro:IPR044538|interpro:IPR023175|refseq:NP_492139.3|wormbase:T23G11.7b|interpro:IPR039431|interpro:IPR041212|uniprotkb:O45812(identity)|wormbase:WBGene00011972(identity) ensemblmetazoa:F46F3.4a.1(transcript)|ensemblmetazoa:WBGene00000146(gene)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:NP_001256353.1|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|wormbase:F46F3.4a|interpro:IPR036028|interpro:IPR036770|refseq:NP_001256354.1|refseq:NP_001256355.1|refseq:NP_001256356.1|wormbase:F46F3.4b|wormbase:F46F3.4c|wormbase:F46F3.4d|uniprotkb:Q9XVN3(identity)|wormbase:WBGene00000146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 35|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:us8aG+qHhgBqqdlUEMIme1essQQ6239 rogid:Y7YswK3q0/HwOelbHJOIgFi08AA6239 intact-crc:474CCA3F0D90598D|rigid:JZNLiNc9sal+jBoU3P811UXbpuE false - sufficient binding region:687-745 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09345 uniprotkb:Q9XVN3 intact:EBI-2006279|ensemblmetazoa:R144.2a.1|ensemblmetazoa:R144.2a.2 intact:EBI-6534803|ensemblmetazoa:F46F3.4a.1|uniprotkb:E0AHC9|uniprotkb:E0AHD0|uniprotkb:E0AHD1 psi-mi:pcf11_caeel(display_long)|uniprotkb:R144.2(orf name)|uniprotkb:pcf-11(gene name)|psi-mi:pcf-11(display_short) psi-mi:iaspp_caeel(display_long)|uniprotkb:ape-1(gene name)|psi-mi:ape-1(display_short)|uniprotkb:Ce-iASPP(gene name synonym)|uniprotkb:Inhibitor member of the ASPP family(gene name synonym)|uniprotkb:F46F3.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534891|imex:IM-18681-284 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498068.1|wormbase:R144.2a|interpro:IPR008942(ENTH/VHS)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|reactome:R-CEL-6807505|reactome:R-CEL-73856|ensemblmetazoa:R144.2a.1(transcript)|ensemblmetazoa:R144.2a.2(transcript)|ensemblmetazoa:WBGene00020092(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|uniprotkb:Q09345(identity)|wormbase:WBGene00020092(identity) ensemblmetazoa:F46F3.4a.1(transcript)|ensemblmetazoa:WBGene00000146(gene)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:NP_001256353.1|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|wormbase:F46F3.4a|interpro:IPR036028|interpro:IPR036770|refseq:NP_001256354.1|refseq:NP_001256355.1|refseq:NP_001256356.1|wormbase:F46F3.4b|wormbase:F46F3.4c|wormbase:F46F3.4d|uniprotkb:Q9XVN3(identity)|wormbase:WBGene00000146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:XTyRR+k9dN5uoxwUXnAuM34SSUA6239 rogid:Y7YswK3q0/HwOelbHJOIgFi08AA6239 intact-crc:6B0650FA9237A335|rigid:SEp3PkTT78G1+Sr6+1D+074+uo0 false - sufficient binding region:687-745 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1ZXS5 uniprotkb:Q9XVN3 intact:EBI-318975|uniprotkb:Q9XUQ4|uniprotkb:A8JJR1|ensemblmetazoa:T08G5.5b.1|intact:EBI-14973910|intact:EBI-6534008 intact:EBI-6534803|ensemblmetazoa:F46F3.4a.1|uniprotkb:E0AHC9|uniprotkb:E0AHD0|uniprotkb:E0AHD1 psi-mi:vps39_caeel(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:iaspp_caeel(display_long)|uniprotkb:ape-1(gene name)|psi-mi:ape-1(display_short)|uniprotkb:Ce-iASPP(gene name synonym)|uniprotkb:Inhibitor member of the ASPP family(gene name synonym)|uniprotkb:F46F3.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534906|imex:IM-18681-285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041163.1|wormbase:T08G5.5a|refseq:NP_001041164.1|refseq:NP_001123010.1|wormbase:T08G5.5b|wormbase:T08G5.5c|ensemblmetazoa:T08G5.5b.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|interpro:IPR001180(Citron-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019452|interpro:IPR019453|interpro:IPR032914|interpro:IPR036322|dip:DIP-24817N|uniprotkb:A8JJR1(identity)|wormbase:WBGene00011625(identity) ensemblmetazoa:F46F3.4a.1(transcript)|ensemblmetazoa:WBGene00000146(gene)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:NP_001256353.1|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|wormbase:F46F3.4a|interpro:IPR036028|interpro:IPR036770|refseq:NP_001256354.1|refseq:NP_001256355.1|refseq:NP_001256356.1|wormbase:F46F3.4b|wormbase:F46F3.4c|wormbase:F46F3.4d|uniprotkb:Q9XVN3(identity)|wormbase:WBGene00000146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 19|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2017/10/20 rogid:OY+zb1zby7cfHD+BQwKt56yw7HY6239 rogid:Y7YswK3q0/HwOelbHJOIgFi08AA6239 intact-crc:98EF473DFB8698C4|rigid:X5BXKqQIXNFEqh0cIkGQ3TwjXRQ false - sufficient binding region:687-745 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:P39055 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534938|imex:IM-18681-287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 26|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:3127340B836DCF99|rigid:N98o9RGxYw7RG11wpJnmOwOBARk false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q09442 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534955|imex:IM-18681-288 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 intact-crc:512039A09AB0AEE6|rigid:ngmNj5aPzhcXg33DYJF+LKvBKes false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:G5ED57 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-327853|ensemblmetazoa:F22E12.1.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:g5ed57_caeel(display_long)|uniprotkb:F22E12.1(orf name)|uniprotkb:CELE_F22E12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535000|imex:IM-18681-291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) uniprotkb:O45916(uniprot-removed-ac)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR020901|refseq:NP_505684.2|wormbase:F22E12.1|ensemblmetazoa:F22E12.1.1(transcript)|ensemblmetazoa:WBGene00009058(gene)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036880|uniprotkb:G5ED57(identity)|wormbase:WBGene00009058(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:+Rdyx7pnykvpAExFI2L56AHfbIc6239 intact-crc:10813A9A3DF9850C|rigid:NBVAfL8xdRjlt9SKpVwGT7Pl3Fo false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93203 uniprotkb:O45539 intact:EBI-315294|ensemblmetazoa:C11E4.6.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:q93203_caeel(display_long)|uniprotkb:C11E4.6(orf name)|uniprotkb:CELE_C11E4.6(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534970|imex:IM-18681-289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509620.2|wormbase:C11E4.6|ensemblmetazoa:C11E4.6.1(transcript)|ensemblmetazoa:WBGene00007520(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|dip:DIP-25879N|uniprotkb:Q93203(identity)|wormbase:WBGene00007520(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 23|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4lnus3cgxAI4dQDe0XjYAgmH2us6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:C607805ECE16CA92|rigid:buCQduaeUnnCJDBnWNG7Tr2VuBk false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A1C3NSL9 uniprotkb:O45539 intact:EBI-327553|ensemblmetazoa:C25A11.4k.1|intact:EBI-11468732|uniprotkb:A0A1C3NSK1|uniprotkb:A0A1C3NSK9|uniprotkb:A0A1C3NSL1|uniprotkb:A0A1C3NSL6|uniprotkb:A0A1C3NSM8|uniprotkb:A0A1C3NSP2|uniprotkb:A0A1C3NSQ2|uniprotkb:G4RTG4|uniprotkb:H2KYC4|uniprotkb:H2KYC6 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:ajm1_caeel(display_long)|uniprotkb:ajm-1(gene name)|psi-mi:ajm-1(display_short)|uniprotkb:CELE_C25A11.4(orf name)|uniprotkb:C25A11.4(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6534985|imex:IM-18681-290 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q18138(uniprot-removed-ac)|interpro:IPR038825|wormbase:C25A11.4e|interpro:IPR002893(Zinc finger, MYND-type)|ensemblmetazoa:C25A11.4k.1(transcript)|ensemblmetazoa:WBGene00000100(gene)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044292"(dendrite terminus)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046872"(metal ion binding)|refseq:NP_001317735.1|refseq:NP_001317736.1|refseq:NP_001317888.1|refseq:NP_001317890.1|refseq:NP_001317891.1|refseq:NP_001317897.1|refseq:NP_001317898.1|refseq:NP_001317899.1|refseq:NP_509536.1|refseq:NP_001317887.1|refseq:NP_001317889.1|wormbase:C25A11.4a|wormbase:C25A11.4d|wormbase:C25A11.4f|wormbase:C25A11.4g|wormbase:C25A11.4h|wormbase:C25A11.4i|wormbase:C25A11.4j|wormbase:C25A11.4k|wormbase:C25A11.4l|wormbase:C25A11.4m|uniprotkb:G4RTG4(identity)|wormbase:WBGene00000100(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/26 rogid:r7BJygBJ3u4aJy/4+mWnsMDUgLo6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:54E2895A920FA529|rigid:ruB4im+zbQYlMuGOzXD/ZsQRU/k false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65ZB4 uniprotkb:O45539 intact:EBI-6532971|ensemblmetazoa:F54D5.15b.1|ensemblmetazoa:F54D5.15b.2 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:q65zb4_caeel(display_long)|uniprotkb:CELE_F54D5.15(orf name)|uniprotkb:F54D5.15(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535045|imex:IM-18681-294 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F54D5.15b.1(transcript)|ensemblmetazoa:F54D5.15b.2(transcript)|ensemblmetazoa:WBGene00010057(gene)|refseq:NP_001022200.1|wormbase:F54D5.15b|uniprotkb:Q65ZB4(identity)|wormbase:WBGene00010057(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:HNrF4GLN9SQWi6CrHUP8geHepb06239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:B0D6308D37779D33|rigid:FJo3/dg6Ar0dpI7FGYBDekYcU0A false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:E3W743 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535015|imex:IM-18681-292 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 intact-crc:079AF9D344A9DA38|rigid:DUxfmooj+Ub4mOe9U4m5LxU/Oic false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:G5ECW9 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-315316|ensemblmetazoa:F46F6.1a.1|ensemblmetazoa:F46F6.1a.2 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:g5ecw9_caeel(display_long)|uniprotkb:rme-4(gene name)|psi-mi:rme-4(display_short)|uniprotkb:F46F6.1(orf name)|uniprotkb:CELE_F46F6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535030|imex:IM-18681-293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) uniprotkb:Q20473(uniprot-removed-ac)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|refseq:NP_509739.1|wormbase:F46F6.1a|mint:G5ECW9|ensemblmetazoa:F46F6.1a.1(transcript)|ensemblmetazoa:F46F6.1a.2(transcript)|ensemblmetazoa:WBGene00004375(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR043153|interpro:IPR040032|interpro:IPR037516|uniprotkb:G5ECW9(identity)|wormbase:WBGene00004375(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 22|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:3FE5ecvvghPRxJTDrlb8Ij9Vzx46239 intact-crc:05656ABB524C3E5C|rigid:DD7VnvRt3MYwBrUmFBPh8MmH2Mc false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:O01900 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535060|imex:IM-18681-295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 intact-crc:9F94BCD0A994AD7E|rigid:zGDrYa6B/Rwcvt21qBV+9uc92eQ false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21301 uniprotkb:O45539 intact:EBI-6535075|ensemblmetazoa:K07G5.1.1|ensemblmetazoa:K07G5.1.2 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:q21301_caeel(display_long)|uniprotkb:K07G5.1(orf name)|uniprotkb:crml-1(gene name)|psi-mi:crml-1(display_short)|uniprotkb:CELE_K07G5.1(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535077|imex:IM-18681-296 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K07G5.1.1(transcript)|ensemblmetazoa:K07G5.1.2(transcript)|ensemblmetazoa:WBGene00010641(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035021"(negative regulation of Rac protein signal transduction)|go:"GO:0040011"(locomotion)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|interpro:IPR032675|refseq:NP_001309450.1|reactome:R-CEL-983231|interpro:IPR001611(Leucine-rich repeat)|wormbase:K07G5.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR041245|uniprotkb:Q21301(identity)|wormbase:WBGene00010641(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 36|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/06/06 rogid:ueKQAU0QgvkuSQUh9ZBlF7V+uMk6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:61369F3A7584E56F|rigid:qCo9Hupw9LwneAqdleOyhf52+nQ false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:P91820 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535124|imex:IM-18681-299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N|uniprotkb:P91820(identity)|wormbase:WBGene00003083(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 intact-crc:97CB46D34E8058B8|rigid:JhEvddEdQpfy9cuEHgU0t9as5xo false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E7EM33 uniprotkb:O45539 intact:EBI-6535096|ensemblmetazoa:K11E8.1q.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:e7em33_caeel(display_long)|uniprotkb:K11E8.1(orf name)|uniprotkb:unc-43(gene name)|psi-mi:unc-43(display_short)|uniprotkb:CELE_K11E8.1(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535092|imex:IM-18681-297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K11E8.1q.1(transcript)|ensemblmetazoa:WBGene00006779(gene)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|interpro:IPR032710|refseq:NP_001255483.1|wormbase:K11E8.1q|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|uniprotkb:E7EM33(identity)|wormbase:WBGene00006779(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:wJ7Mv8XBGds/21oTfrakhpmcoUM6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:C647E892BA191982|rigid:N77HusEro3ckkyFPjUyj+OXvhZ0 false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q09345 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-2006279|ensemblmetazoa:R144.2a.1|ensemblmetazoa:R144.2a.2 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:pcf11_caeel(display_long)|uniprotkb:R144.2(orf name)|uniprotkb:pcf-11(gene name)|psi-mi:pcf-11(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535109|imex:IM-18681-298 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) refseq:NP_498068.1|wormbase:R144.2a|interpro:IPR008942(ENTH/VHS)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|reactome:R-CEL-6807505|reactome:R-CEL-73856|ensemblmetazoa:R144.2a.1(transcript)|ensemblmetazoa:R144.2a.2(transcript)|ensemblmetazoa:WBGene00020092(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|uniprotkb:Q09345(identity)|wormbase:WBGene00020092(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:XTyRR+k9dN5uoxwUXnAuM34SSUA6239 intact-crc:93426A1D7C6CC974|rigid:TN0MZ+Od2LijQhkawgT7aR5PFyY false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q9U290 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-6535173|ensemblmetazoa:Y48C3A.12.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:q9u290_caeel(display_long)|uniprotkb:CELE_Y48C3A.12(orf name)|uniprotkb:Y48C3A.12(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535169|imex:IM-18681-302 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) reactome:R-CEL-2672351|ensemblmetazoa:WBGene00012994(gene)|ensemblmetazoa:Y48C3A.12.1(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000580(TSC-22 / Dip / Bun)|refseq:NP_496820.3|wormbase:Y48C3A.12|uniprotkb:Q9U290(identity)|wormbase:WBGene00012994(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 25|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:j5mfkqYUtbsxlXm88eVGbYZKfe46239 intact-crc:5EDAC2F29FD6E339|rigid:8imefloC/oEMOrURxJEIRLqIcwE false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45812 uniprotkb:O45539 intact:EBI-6534925|ensemblmetazoa:T23G11.7b.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:o45812_caeel(display_long)|uniprotkb:CELE_T23G11.7(orf name)|uniprotkb:T23G11.7(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535139|imex:IM-18681-300 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T23G11.7b.1(transcript)|ensemblmetazoa:WBGene00011972(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0035493"(SNARE complex assembly)|interpro:IPR044538|interpro:IPR023175|refseq:NP_492139.3|wormbase:T23G11.7b|interpro:IPR039431|interpro:IPR041212|uniprotkb:O45812(identity)|wormbase:WBGene00011972(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:us8aG+qHhgBqqdlUEMIme1essQQ6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:AC803632D582980E|rigid:bZaG4V7scQ+4V8JVOmOd+Sa6MPo false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 intact:EBI-6534333 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 - psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:q965y4_caeel(display_short)|psi-mi:EBI-6534333(display_long)|uniprotkb:Y110A2AM.1(gene name)|psi-mi:Y110A2AM.1(display_short)|uniprotkb:CELE_Y110A2AM.1(orf name)|uniprotkb:Y110A2AM.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535154|imex:IM-18681-301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) uniprotkb:Q965Y4(uniprot-removed-ac)|uniprotkb:Q965Y4(identity)|wormbase:WBGene00022449(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:zqy/LYo1vjSCTC0G4hp+sZ4vti06239 intact-crc:5D12023CC8663F81|rigid:pGSWOGFrhAWhVG6wPvFQ9S0xeAc false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:A5PEX6 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-6532321|ensemblmetazoa:Y57A10A.18b.1|ensemblmetazoa:Y57A10A.18b.2 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:a5pex6_caeel(display_long)|uniprotkb:Y57A10A.18(orf name)|uniprotkb:pqn-87(gene name)|psi-mi:pqn-87(display_short)|uniprotkb:CELE_Y57A10A.18(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535186|imex:IM-18681-303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) ensemblmetazoa:WBGene00004167(gene)|ensemblmetazoa:Y57A10A.18b.1(transcript)|ensemblmetazoa:Y57A10A.18b.2(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|refseq:NP_001122665.1|wormbase:Y57A10A.18b|uniprotkb:A5PEX6(identity)|wormbase:WBGene00004167(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:U79ecDJtHc4bqHRcr6eBglpyv5k6239 intact-crc:5F5526B1975EAE88|rigid:vdMGqt3zw0MOpNvo1njKq742D0o false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:O45539 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535201|imex:IM-18681-304 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 15|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:24EE5EE7424F58FA|rigid:AsrSvdrn7C9mT2A/rElkmwhmCVM false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:Q17865 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535250|imex:IM-18681-307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 32|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:357DB1AEE08161A3|rigid:isCQZOIo50yx99c+fY5uEnFMEQs false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17173 uniprotkb:A6ZJ46 intact:EBI-6535216|ensemblmetazoa:B0454.9.1|ensemblmetazoa:B0454.9.2 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 psi-mi:o17173_caeel(display_long)|uniprotkb:lido-13(gene name)|psi-mi:lido-13(display_short)|uniprotkb:B0454.9(orf name)|uniprotkb:CELE_B0454.9(orf name) psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535218|imex:IM-18681-305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:B0454.9.1(transcript)|ensemblmetazoa:B0454.9.2(transcript)|ensemblmetazoa:WBGene00015200(gene)|go:"GO:0005634"(nucleus)|interpro:IPR005020(Protein of unknown function DUF278)|refseq:NP_494435.1|wormbase:B0454.9|uniprotkb:O17173(identity)|wormbase:WBGene00015200(identity) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:WDCkCYG2SPx9KPXAfnzKz2Xo5546239 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 intact-crc:A80CB94F22902803|rigid:Hd9rB+vF2ZIKb30uUvScxTn1WQE false - sufficient binding region:467-522 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17796 uniprotkb:A6ZJ46 intact:EBI-319625|ensemblmetazoa:C07G1.5.1|ensemblmetazoa:C07G1.5.2 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 psi-mi:q17796_caeel(display_long)|uniprotkb:hgrs-1(gene name)|psi-mi:hgrs-1(display_short)|uniprotkb:CELE_C07G1.5(orf name)|uniprotkb:C07G1.5(orf name) psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535235|imex:IM-18681-306 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501375.2|wormbase:C07G1.5|interpro:IPR024641|ensemblmetazoa:C07G1.5.1(transcript)|ensemblmetazoa:C07G1.5.2(transcript)|ensemblmetazoa:WBGene00004101(gene)|go:"GO:0005769"(early endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|reactome:R-CEL-182971|reactome:R-CEL-432720|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|reactome:R-CEL-6807004|dip:DIP-24324N|reactome:R-CEL-9013420|reactome:R-CEL-9706019|uniprotkb:Q17796(identity)|wormbase:WBGene00004101(identity) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Vt+AmRCoka4jybu2GN4eRvLo+6U6239 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 intact-crc:8ABD5ACDB83C203B|rigid:PTtvnUlq1tdEk8yLifxTzVmNZfo false - sufficient binding region:467-522 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:Q18076 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-2921846|ensemblmetazoa:C18B2.5a.1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:q18076_caeel(display_long)|uniprotkb:C18B2.5(orf name)|uniprotkb:CELE_C18B2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535265|imex:IM-18681-308 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) ensemblmetazoa:C18B2.5a.1(transcript)|ensemblmetazoa:WBGene00015956(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR027417|refseq:NP_741750.1|wormbase:C18B2.5a|dip:DIP-25136N|uniprotkb:Q18076(identity)|wormbase:WBGene00015956(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 37|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:mcd3NaSPJ6tU4fMyCuPRAuL4QOw6239 intact-crc:961BF6367778F5BA|rigid:POEKQ3lMk8Ce8hJHtat5jBtKL9I false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34402 uniprotkb:A6ZJ46 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535280|imex:IM-18681-309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location)|uniprotkb:P34402(identity)|wormbase:WBGene00004726(identity) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 intact-crc:C337E56EDC9FA2B6|rigid:lvaZfGzGzHrNLN+h4bxskXV/ch8 false - sufficient binding region:467-522 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:O62235 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-6535325|ensemblmetazoa:F36F2.3a.1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:o62235_caeel(display_long)|uniprotkb:rbpl-1(gene name)|psi-mi:rbpl-1(display_short)|uniprotkb:CELE_F36F2.3(orf name)|uniprotkb:F36F2.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535327|imex:IM-18681-312 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) ensemblmetazoa:F36F2.3a.1(transcript)|ensemblmetazoa:WBGene00009477(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR003613(U box)|reactome:R-CEL-983168|interpro:IPR025829|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014891(DWNN domain)|refseq:NP_001032975.1|wormbase:F36F2.3a|interpro:IPR036875|interpro:IPR033489|uniprotkb:O62235(identity)|wormbase:WBGene00009477(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:nSFPVut57t8msa+NubrGSmEWLqQ6239 intact-crc:B0C11F0D31548518|rigid:mxzJp0f3x4Dn/FVTSUsMg0oqP7U false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E3W743 uniprotkb:A6ZJ46 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535295|imex:IM-18681-310 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 intact-crc:CD3B0E3AF9DF1436|rigid:vSUFBdpMiio8UtuFd6PxXPWQ8jc false - sufficient binding region:467-522 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:O62203 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-320780|ensemblmetazoa:F32B4.4a.1|intact:EBI-6530763|uniprotkb:F5GUF6|uniprotkb:Q7Z0X2 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:phm2_caeel(display_long)|uniprotkb:phm-2(gene name)|psi-mi:phm-2(display_short)|uniprotkb:F32B4.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535310|imex:IM-18681-311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) wormbase:F32B4.4a|ensemblmetazoa:F32B4.4a.1(transcript)|ensemblmetazoa:WBGene00009314(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007586"(digestion)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036361|refseq:NP_001021441.1|refseq:NP_001251667.1|refseq:NP_001021440.2|dip:DIP-25849N|reactome:R-CEL-3899300|wormbase:F32B4.4b|wormbase:F32B4.4c|uniprotkb:F5GUF6(identity)|wormbase:WBGene00009314(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/03/02 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:69Kg/RUbe1gThWpe8yrWyt9o0bQ6239 intact-crc:4D450E10172FD0B4|rigid:04+Ru9mwmTkhBtDhMg5JAuFj2wM false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:Q9XVN3 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-6534803|ensemblmetazoa:F46F3.4a.1|uniprotkb:E0AHC9|uniprotkb:E0AHD0|uniprotkb:E0AHD1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:iaspp_caeel(display_long)|uniprotkb:ape-1(gene name)|psi-mi:ape-1(display_short)|uniprotkb:Ce-iASPP(gene name synonym)|uniprotkb:Inhibitor member of the ASPP family(gene name synonym)|uniprotkb:F46F3.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535342|imex:IM-18681-313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) ensemblmetazoa:F46F3.4a.1(transcript)|ensemblmetazoa:WBGene00000146(gene)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:NP_001256353.1|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|wormbase:F46F3.4a|interpro:IPR036028|interpro:IPR036770|refseq:NP_001256354.1|refseq:NP_001256355.1|refseq:NP_001256356.1|wormbase:F46F3.4b|wormbase:F46F3.4c|wormbase:F46F3.4d|uniprotkb:Q9XVN3(identity)|wormbase:WBGene00000146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 41|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:Y7YswK3q0/HwOelbHJOIgFi08AA6239 intact-crc:BFE7DC6E2C4D53EE|rigid:DSV7UeHQmh2nvIRXqM8c6jIw3CQ false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:D3YT78 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-6535361|ensemblmetazoa:F52G2.2c.1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:d3yt78_caeel(display_long)|uniprotkb:F52G2.2(orf name)|uniprotkb:rsd-2(gene name)|psi-mi:rsd-2(display_short)|uniprotkb:CELE_F52G2.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535357|imex:IM-18681-314 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) interpro:IPR040930|ensemblmetazoa:F52G2.2c.1(transcript)|ensemblmetazoa:WBGene00004681(gene)|refseq:NP_001255750.1|wormbase:F52G2.2c|uniprotkb:D3YT78(identity)|wormbase:WBGene00004681(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:960JY36NqUHRe3mTtqUwWbV6UjM6239 intact-crc:DA1FEB861B3D552F|rigid:puOUi/wSVzIEgA8h92YyleWFGM0 false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ59 uniprotkb:A6ZJ46 intact:EBI-6535378|ensemblmetazoa:T04F8.7b.1 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 psi-mi:a6zj59_caeel(display_long)|uniprotkb:CELE_T04F8.7(orf name)|uniprotkb:T04F8.7(orf name) psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535374|imex:IM-18681-315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T04F8.7b.1(transcript)|ensemblmetazoa:WBGene00011445(gene)|refseq:NP_001123178.1|wormbase:T04F8.7b|interpro:IPR036028|uniprotkb:A6ZJ59(identity)|wormbase:WBGene00011445(identity) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:uPiWv8V5lvlkGx9q4Q4Uu1lmY9I6239 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 intact-crc:8090259FB0569FC0|rigid:M1FMWW1htd+VkCw9Zbq1VOY/z/g false - sufficient binding region:467-522 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:O02174 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-2315779|ensemblmetazoa:W05H7.4a.1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:o02174_caeel(display_long)|uniprotkb:zfp-3(gene name)|psi-mi:zfp-3(display_short)|uniprotkb:CELE_W05H7.4(orf name)|uniprotkb:W05H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535401|imex:IM-18681-316 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) refseq:NP_741720.2|wormbase:W05H7.4a|dip:DIP-24700N|ensemblmetazoa:W05H7.4a.1(transcript)|ensemblmetazoa:WBGene00021047(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|uniprotkb:O02174(identity)|wormbase:WBGene00021047(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 30|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:R0h2ws5KoHLO1xjsdYiNFhPwqWM6239 intact-crc:F0424520D77F493E|rigid:vdD5zHofHZ1xU4+3mET5uhSsLxo false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91561 uniprotkb:A6ZJ46 intact:EBI-6535420|ensemblmetazoa:ZC239.14.1 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 psi-mi:p91561_caeel(display_long)|uniprotkb:CELE_ZC239.14(orf name)|uniprotkb:ZC239.14(orf name) psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535416|imex:IM-18681-317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00022572(gene)|ensemblmetazoa:ZC239.14.1(transcript)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_494479.2|wormbase:ZC239.14|uniprotkb:P91561(identity)|wormbase:WBGene00022572(identity) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:B9K5CXRQesCPQ1Yc8zTFWexS4zg6239 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 intact-crc:891F3C99AAB82AC5|rigid:8AxbM2F91BG6QXTKH+UnSoXOqAw false - sufficient binding region:467-522 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44577 uniprotkb:A6ZJ46 intact:EBI-325053|ensemblmetazoa:ZK697.2a.1 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 psi-mi:o44577_caeel(display_long)|uniprotkb:nhr-256(gene name)|psi-mi:nhr-256(display_short)|uniprotkb:CELE_ZK697.2(orf name)|uniprotkb:ZK697.2(orf name) psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535433|imex:IM-18681-318 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_503495.1|ensemblmetazoa:WBGene00022805(gene)|ensemblmetazoa:ZK697.2a.1(transcript)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|wormbase:ZK697.2a|dip:DIP-27064N|uniprotkb:O44577(identity)|wormbase:WBGene00022805(identity) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Dgjqh+ojEoFl1lqFqRfQFsJoGjI6239 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 intact-crc:B14D3799199B81BD|rigid:J8ZmPsFN8yfMVUlaUyC0VEscuA4 false - sufficient binding region:467-522 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:Q8MLZ5 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-6535448|ensemblmetazoa:ZK899.8a.1|uniprotkb:A6ZJ45|uniprotkb:K8ERX6|uniprotkb:K8ERY0|uniprotkb:K8ESF6|uniprotkb:K8ESL7|uniprotkb:K8F7Z7|uniprotkb:K8FE04|uniprotkb:M1ZJ21|uniprotkb:M1ZMJ4|uniprotkb:Q3S1K5|uniprotkb:O44242|uniprotkb:Q9TVD9|uniprotkb:O44243|uniprotkb:O44244|uniprotkb:O44245|uniprotkb:Q9TVE0|uniprotkb:Q9TVE1|uniprotkb:Q9TVE2|uniprotkb:Q9TVE3|uniprotkb:Q9TVE4|uniprotkb:Q9U991|uniprotkb:Q9UAH9|uniprotkb:Q9UAI0|uniprotkb:O44239|uniprotkb:O44240|uniprotkb:O44241 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:gap2_caeel(display_long)|uniprotkb:gap-2(gene name)|psi-mi:gap-2(display_short)|uniprotkb:ZK899.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535450|imex:IM-18681-319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) ensemblmetazoa:WBGene00001516(gene)|ensemblmetazoa:ZK899.8a.1(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008306"(associative learning)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|refseq:NP_001033580.1|refseq:NP_001123198.1|refseq:NP_001294843.1|refseq:NP_001294845.1|refseq:NP_509595.1|refseq:NP_509596.1|refseq:NP_509597.1|refseq:NP_509598.1|refseq:NP_509599.1|refseq:NP_741873.1|wormbase:ZK899.8i|wormbase:ZK899.8j|wormbase:ZK899.8k|wormbase:ZK899.8l|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|refseq:NP_509594.3|refseq:NP_741874.1|wormbase:ZK899.8a|wormbase:ZK899.8b|wormbase:ZK899.8c|wormbase:ZK899.8d|wormbase:ZK899.8e|wormbase:ZK899.8f|wormbase:ZK899.8g|wormbase:ZK899.8h|interpro:IPR035892|interpro:IPR039360|uniprotkb:Q8MLZ5(identity)|wormbase:WBGene00001516(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 73|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:uC7TVo4HBF186kUMIPx6LrNEkog6239 intact-crc:1DD52F5A518F1383|rigid:PrC7nPvfW+808WPFU54aSUV/F94 false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76572 uniprotkb:Q18320 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 intact:EBI-327120|ensemblmetazoa:C30B5.1.1 psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:q18320_caeel(display_long)|uniprotkb:szy-4(gene name)|psi-mi:szy-4(display_short)|uniprotkb:CELE_C30B5.1(orf name)|uniprotkb:C30B5.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535467|imex:IM-18681-320 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) refseq:NP_495240.3|wormbase:C30B5.1|ensemblmetazoa:C30B5.1.1(transcript)|ensemblmetazoa:WBGene00077732(gene)|go:"GO:0010824"(regulation of centrosome duplication)|dip:DIP-26627N|uniprotkb:Q18320(identity)|wormbase:WBGene00016243(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 rogid:6IqpSSIKuKFLXLTuaEL2dI5mqF06239 intact-crc:2AD40E19280473D9|rigid:/qObpbizKkP4CXu6LzmEhuCvCmI false sufficient binding region:532-589 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18529 uniprotkb:O76572 intact:EBI-314884|ensemblmetazoa:C39D10.7.2|ensemblmetazoa:C39D10.7.1 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:q18529_caeel(display_long)|uniprotkb:C39D10.7(orf name)|uniprotkb:CELE_C39D10.7(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535482|imex:IM-18681-321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509334.3|wormbase:C39D10.7|ensemblmetazoa:C39D10.7.2(transcript)|ensemblmetazoa:WBGene00016534(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008061"(chitin binding)|interpro:IPR002557(Chitin binding protein, peritrophin-A)|interpro:IPR036508|ensemblmetazoa:C39D10.7.1(transcript)|dip:DIP-27006N|uniprotkb:Q18529(identity)|wormbase:WBGene00016534(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:gnU6jSkV05zYFXSGRFYUIcPLW5Q6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:AE8A43E8FA0A78D5|rigid:QrPt5jcp5yQMjecWH389KLaSplo false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76572 uniprotkb:G5ED57 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 intact:EBI-327853|ensemblmetazoa:F22E12.1.1 psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:g5ed57_caeel(display_long)|uniprotkb:F22E12.1(orf name)|uniprotkb:CELE_F22E12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535497|imex:IM-18681-322 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) uniprotkb:O45916(uniprot-removed-ac)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR020901|refseq:NP_505684.2|wormbase:F22E12.1|ensemblmetazoa:F22E12.1.1(transcript)|ensemblmetazoa:WBGene00009058(gene)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036880|uniprotkb:G5ED57(identity)|wormbase:WBGene00009058(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 rogid:+Rdyx7pnykvpAExFI2L56AHfbIc6239 intact-crc:E5E2DD0FF30C6336|rigid:/yjm1C3Hj7nZIDNJ7id4c7odRVE false sufficient binding region:532-589 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED20 uniprotkb:O76572 intact:EBI-319647|ensemblmetazoa:F26G5.9.1 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:g5ed20_caeel(display_long)|uniprotkb:tam-1(gene name)|psi-mi:tam-1(display_short)|uniprotkb:CELE_F26G5.9(orf name)|uniprotkb:F26G5.9(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535527|imex:IM-18681-324 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O16936(uniprot-removed-ac)|interpro:IPR027370|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR017907|refseq:NP_504335.1|ensemblmetazoa:F26G5.9.1(transcript)|ensemblmetazoa:WBGene00006523(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000785"(chromatin)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0043073"(germ cell nucleus)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|wormbase:F26G5.9|reactome:R-CEL-3108214|reactome:R-CEL-8934593|reactome:R-CEL-8948747|uniprotkb:G5ED20(identity)|wormbase:WBGene00006523(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BZmiHrHEQepSGkEZzAc0jHJXnNE6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:BB5D9DF4917CED58|rigid:wnt5iIYwHA5mC6PV5SvTKbSOBHQ false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B3GWA0 uniprotkb:O76572 intact:EBI-6534207|ensemblmetazoa:F25B5.7c.1 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:b3gwa0_caeel(display_long)|uniprotkb:nono-1(gene name)|psi-mi:nono-1(display_short)|uniprotkb:CELE_F25B5.7(orf name)|uniprotkb:F25B5.7(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535512|imex:IM-18681-323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F25B5.7c.1(transcript)|ensemblmetazoa:WBGene00017778(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR012975(NOPS)|refseq:NP_498296.3|wormbase:F25B5.7c|uniprotkb:B3GWA0(identity)|wormbase:WBGene00017778(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lWJ7KO5EiJ5HtKHW+fGsAOn5RhU6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:47EEDCAE42709177|rigid:Qj0Bs6OQWvRV0kZRhlFtUd7DiaY false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E3W743 uniprotkb:O76572 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535557|imex:IM-18681-326 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:5AC51DB0F4DE45FB|rigid:BYds5vf6B1GxGXGn/vltdjxc1WA false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20010 uniprotkb:O76572 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535572|imex:IM-18681-327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N|uniprotkb:Q20010(identity)|wormbase:WBGene00009385(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:4809535E94C62730|rigid:jozXGTuu4JoajVg80bvi9iUr2ZM false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76572 uniprotkb:Q19905 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535542|imex:IM-18681-325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N|uniprotkb:Q19905(identity)|wormbase:WBGene00005022(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 intact-crc:24C4ABC7EADC1D4E|rigid:Pb6QeRk3zv5VGoA2RoYgVOLSi8c false sufficient binding region:532-589 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76572 uniprotkb:G5ECL2 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535587|imex:IM-18681-328 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 intact-crc:25857E845CC2643B|rigid:qsnJUMYvQF9tVZ8CjhXeWaGdiq4 false sufficient binding region:532-589 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17139 uniprotkb:O76572 intact:EBI-319671|uniprotkb:Q6LAD0|ensemblmetazoa:K04H4.1a.1 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:co4a1_caeel(display_long)|uniprotkb:emb-9(gene name)|psi-mi:emb-9(display_short)|uniprotkb:clb-2(gene name synonym)|uniprotkb:K04H4.1(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535602|imex:IM-18681-329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|refseq:NP_001022663.1|wormbase:K04H4.1a|wormbase:K04H4.1b|refseq:NP_001022662.2|ensemblmetazoa:K04H4.1a.1(transcript)|ensemblmetazoa:WBGene00001263(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005587"(collagen type IV trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050714"(positive regulation of protein secretion)|interpro:IPR036954|uniprotkb:P17139(identity)|wormbase:WBGene00001263(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:PAygwwh1z4+A+1x0KmF3LiN6qKw6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:9918A53DAF66B9CB|rigid:sdAfz4JKfXDI8/LPQdHL+T8Y+Co false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76572 uniprotkb:Q09345 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 intact:EBI-2006279|ensemblmetazoa:R144.2a.1|ensemblmetazoa:R144.2a.2 psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:pcf11_caeel(display_long)|uniprotkb:R144.2(orf name)|uniprotkb:pcf-11(gene name)|psi-mi:pcf-11(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535632|imex:IM-18681-331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) refseq:NP_498068.1|wormbase:R144.2a|interpro:IPR008942(ENTH/VHS)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|reactome:R-CEL-6807505|reactome:R-CEL-73856|ensemblmetazoa:R144.2a.1(transcript)|ensemblmetazoa:R144.2a.2(transcript)|ensemblmetazoa:WBGene00020092(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|uniprotkb:Q09345(identity)|wormbase:WBGene00020092(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 rogid:XTyRR+k9dN5uoxwUXnAuM34SSUA6239 intact-crc:37B32806F065175A|rigid:TPV6yk+/ri8U3TgMiLsnF0OSQEw false sufficient binding region:532-589 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21878 uniprotkb:O76572 intact:EBI-323415|uniprotkb:Q867F1|uniprotkb:Q86PL0|uniprotkb:Q86PL1|ensemblmetazoa:R09G11.2a.1|ensemblmetazoa:R09G11.2a.2 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:nhr1_caeel(display_long)|uniprotkb:nhr-1(gene name)|psi-mi:nhr-1(display_short)|uniprotkb:R09G11.2(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535617|imex:IM-18681-330 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|refseq:NP_001024853.1|refseq:NP_001024855.1|wormbase:R09G11.2a|wormbase:R09G11.2c|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|ensemblmetazoa:R09G11.2a.1(transcript)|ensemblmetazoa:R09G11.2a.2(transcript)|ensemblmetazoa:WBGene00003600(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0047484"(regulation of response to osmotic stress)|go:"GO:0048856"(anatomical structure development)|interpro:IPR035500|uniprotkb:Q21878(identity)|wormbase:WBGene00003600(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:CMwN/zd5ysV40iKyGMFPjPNMCbI6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:7F19898ADAC579E5|rigid:af4fKy3KeBDFyYQUvLXs7ODrG8Q false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76572 uniprotkb:P91482 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 intact:EBI-315371|ensemblmetazoa:T20F5.6.1 psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:p91482_caeel(display_long)|uniprotkb:T20F5.6(orf name)|uniprotkb:CELE_T20F5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535681|imex:IM-18681-334 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) refseq:NP_491266.1|wormbase:T20F5.6|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|ensemblmetazoa:T20F5.6.1(transcript)|ensemblmetazoa:WBGene00020628(gene)|go:"GO:0046872"(metal ion binding)|uniprotkb:P91482(identity)|wormbase:WBGene00020628(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 rogid:XgUfhY6bbYdTU31B8yVQiDR2+KA6239 intact-crc:787B146F844CEA25|rigid:5tRBLAgaPoYl91p3GIQWRMm0sZU false sufficient binding region:532-589 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76572 uniprotkb:Q95ZK7 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 intact:EBI-317828|uniprotkb:Q95ZK6|intact:EBI-6535651|ensemblmetazoa:T07F8.3a.1|ensemblmetazoa:T07F8.3b.1 psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:gld3_caeel(display_long)|uniprotkb:gld-3(gene name)|psi-mi:gld-3(display_short)|uniprotkb:Germline development defective 3(gene name synonym)|uniprotkb:T07F8.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535647|imex:IM-18681-332 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) wormbase:T07F8.3b|refseq:NP_495479.2|wormbase:T07F8.3a|go:"GO:0002119"(nematode larval development)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018992"(germ-line sex determination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031379"(RNA-directed RNA polymerase complex)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0040025"(vulval development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0043186"(P granule)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051100"(negative regulation of binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR041194|rcsb pdb:3N89|rcsb pdb:4ZRL|ensemblmetazoa:T07F8.3a.1(transcript)|ensemblmetazoa:T07F8.3b.1(transcript)|ensemblmetazoa:WBGene00001597(gene)|ensemblmetazoa:WBGene00001597(gene)|go:"GO:0000280"(nuclear division)|dip:DIP-25960N|ensemblmetazoa:WBGene00001597(gene)|refseq:NP_495480.1|uniprotkb:Q95ZK6(identity)|wormbase:WBGene00001597(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 rogid:oMMD8nEZ6mDnNIjvEgVPh0HXClg6239 intact-crc:C160D7FB08F2E033|rigid:BBcrC0lQIEj3ndGyJpeCzymSWOk false sufficient binding region:532-589 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EGI1 uniprotkb:O76572 intact:EBI-6535668|ensemblmetazoa:T12D8.1.1 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:g5egi1_caeel(display_long)|uniprotkb:T12D8.1(orf name)|uniprotkb:set-16(gene name)|psi-mi:set-16(display_short)|uniprotkb:CELE_T12D8.1(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535664|imex:IM-18681-333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3214841|reactome:R-CEL-8936459|ensemblmetazoa:T12D8.1.1(transcript)|ensemblmetazoa:WBGene00011729(gene)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR034732|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|refseq:NP_499819.3|wormbase:T12D8.1|interpro:IPR036910|reactome:R-CEL-201722|uniprotkb:G5EGI1(identity)|wormbase:WBGene00011729(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:80BsnXv3J14R8mQxBLm6PJYel0Q6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:4AF3D9FDB2315656|rigid:tfx9Z0dTGIISvbAdxRjtvtyiLIU false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91820 uniprotkb:O76572 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535696|imex:IM-18681-335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N|uniprotkb:P91820(identity)|wormbase:WBGene00003083(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 16|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:4F346A3542BA7984|rigid:AYpTmxdVU/l4mmM/0zodKnvj4k0 false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76572 uniprotkb:O18181 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 intact:EBI-314025|ensemblmetazoa:W09D10.1.1|ensemblmetazoa:W09D10.1.2|ensemblmetazoa:W09D10.1.3 psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:o18181_caeel(display_long)|uniprotkb:W09D10.1(orf name)|uniprotkb:CELE_W09D10.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535711|imex:IM-18681-336 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) refseq:NP_499364.1|wormbase:W09D10.1|ensemblmetazoa:W09D10.1.1(transcript)|ensemblmetazoa:W09D10.1.2(transcript)|ensemblmetazoa:W09D10.1.3(transcript)|ensemblmetazoa:WBGene00012359(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|interpro:IPR044732|dip:DIP-25493N|uniprotkb:O18181(identity)|wormbase:WBGene00012359(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 rogid:cHeZ4L5WfJqv9iJlDcYYy+cOz3k6239 intact-crc:419434739D604140|rigid:0T7nvw9Z/EU1y6TSZbvKEm8gpGk false sufficient binding region:532-589 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWN1 uniprotkb:O76572 intact:EBI-324865|ensemblmetazoa:Y43F8C.6a.1 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:q9xwn1_caeel(display_long)|uniprotkb:Y43F8C.6(orf name)|uniprotkb:CELE_Y43F8C.6(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535756|imex:IM-18681-339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256880.1|wormbase:Y43F8C.6a|ensemblmetazoa:WBGene00012828(gene)|ensemblmetazoa:Y43F8C.6a.1(transcript)|go:"GO:0016589"(NURF complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR037931|dip:DIP-27198N|uniprotkb:Q9XWN1(identity)|wormbase:WBGene00012828(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BnRBxnWaRRWRCAx+LGlNwRaOcOU6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:87C32226147D342A|rigid:DvIkXeSo/rfedn/SaKH/LWzGIH8 false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U304 uniprotkb:O76572 intact:EBI-329038|ensemblmetazoa:Y106G6D.7.1 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:q9u304_caeel(display_long)|uniprotkb:rbm-12(gene name)|psi-mi:rbm-12(display_short)|uniprotkb:CELE_Y106G6D.7(orf name)|uniprotkb:Y106G6D.7(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535726|imex:IM-18681-337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492671.1|wormbase:Y106G6D.7|dip:DIP-26480N|ensemblmetazoa:WBGene00013703(gene)|ensemblmetazoa:Y106G6D.7.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-CEL-72163|uniprotkb:Q9U304(identity)|wormbase:WBGene00013703(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:/8MJkmHgCyjvgK0ZmDnklHVfJrw6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:61ED9A8611D8A057|rigid:LZv5RNvzAMNxaDJSSNF/I7hRYew false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWR1 uniprotkb:O76572 intact:EBI-2002612|intact:EBI-6534487|uniprotkb:A7DTF1|uniprotkb:D3NQA3|ensemblmetazoa:Y11D7A.12a.1 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:flh1_caeel(display_long)|uniprotkb:flh-1(gene name)|psi-mi:flh-1(display_short)|uniprotkb:Y11D7A.12(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535741|imex:IM-18681-338 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501618.2|wormbase:Y11D7A.12a|wormbase:Y11D7A.12b|wormbase:Y11D7A.12c|dip:DIP-24849N|ensemblmetazoa:WBGene00012435(gene)|ensemblmetazoa:Y11D7A.12a.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR007588(Zinc finger, FLYWCH-type)|uniprotkb:A7DTF1(identity)|wormbase:WBGene00012435(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2021/11/30 rogid:BUwEONwxmU5dE1HyJh2inla8obA6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:0229DB1BD90B09D3|rigid:IvewbNlb4t7by9fUmfLjIsYEvA0 false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q4VNJ8 uniprotkb:O76572 intact:EBI-2918529 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535786|imex:IM-18681-341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:4DFBFDDA76F61016|rigid:FOpAn+atZ2Bti+vE3Ww9dNSPo38 false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76572 uniprotkb:Q8WTJ8 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 intact:EBI-321112|ensemblmetazoa:Y51F10.2a.1|ensemblmetazoa:Y51F10.2a.2 psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:q8wtj8_caeel(display_long)|uniprotkb:Y51F10.2(orf name)|uniprotkb:CELE_Y51F10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535771|imex:IM-18681-340 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) refseq:NP_740796.1|ensemblmetazoa:WBGene00021763(gene)|ensemblmetazoa:Y51F10.2a.1(transcript)|ensemblmetazoa:Y51F10.2a.2(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|wormbase:Y51F10.2a|dip:DIP-26335N|uniprotkb:Q8WTJ8(identity)|wormbase:WBGene00021763(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 rogid:ecYf0rK4DGesDNxewp2Vg2bxK/Y6239 intact-crc:506D4D856B6E86C2|rigid:WTjszF3ZjA0Be5dkIR5mRH5AcII false sufficient binding region:532-589 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32085 uniprotkb:Q9XUS7-2 intact:EBI-313377|ensemblmetazoa:T20B12.2.1 intact:EBI-12629275|ensemblmetazoa:K08E3.3a.1 psi-mi:tbp_caeel(display_long)|uniprotkb:tbp-1(gene name)|psi-mi:tbp-1(display_short)|uniprotkb:tbp(gene name synonym)|uniprotkb:T20B12.2(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:q9xus7-2(display_long)|uniprotkb:toca-2(gene name)|psi-mi:toca-2(display_short)|uniprotkb:K08E3.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535803|imex:IM-18681-342 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498635.1|wormbase:T20B12.2|ensemblmetazoa:T20B12.2.1(transcript)|ensemblmetazoa:WBGene00006542(gene)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|go:"GO:0006352"(DNA-templated transcription, initiation)|reactome:R-CEL-6807505|reactome:R-CEL-674695|reactome:R-CEL-73776|reactome:R-CEL-73779|reactome:R-CEL-75953|reactome:R-CEL-76042|reactome:R-CEL-9018519|dip:DIP-26447N|reactome:R-CEL-73772|uniprotkb:P32085(identity)|wormbase:WBGene00006542(identity) intact:EBI-6535801(isoform-parent)|ensemblmetazoa:K08E3.3a.1(transcript)|ensemblmetazoa:WBGene00010663(gene)|uniprotkb:Q9U3B8(identity)|wormbase:WBGene00010663(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:o7s313h1WbgESEEeKW35tAqWX2k6239 rogid:q8SSrrDQKHiHNPSBWBHPUrgGZjg6239 intact-crc:AA7A73C5276FEF30|rigid:44JfJV20A63Q0aYIfjEnVScQKe4 false - sufficient binding region:550-608 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4S034 uniprotkb:O45233 intact:EBI-6535822|ensemblmetazoa:K10B3.10a.1 intact:EBI-330100|ensemblmetazoa:C01G12.1.1 psi-mi:g4s034_caeel(display_long)|uniprotkb:K10B3.10(orf name)|uniprotkb:spc-1(gene name)|psi-mi:spc-1(display_short)|uniprotkb:CELE_K10B3.10(orf name) psi-mi:o45233_caeel(display_long)|uniprotkb:C01G12.1(orf name)|uniprotkb:madf-5(gene name)|psi-mi:madf-5(display_short)|uniprotkb:CELE_C01G12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535818|imex:IM-18681-343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K10B3.10a.1(transcript)|ensemblmetazoa:WBGene00004951(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051693"(actin filament capping)|interpro:IPR035825|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|wormbase:K10B3.10a|interpro:IPR018159|interpro:IPR018247|refseq:NP_001256999.1|interpro:IPR036028|uniprotkb:G4S034(identity)|wormbase:WBGene00004951(identity) refseq:NP_497028.1|wormbase:C01G12.1|dip:DIP-27356N|ensemblmetazoa:C01G12.1.1(transcript)|ensemblmetazoa:WBGene00007242(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR004210(BESS motif)|interpro:IPR006578(MADF)|interpro:IPR039353|uniprotkb:O45233(identity)|wormbase:WBGene00007242(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 25|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:98NuGykSfInnIVkxQiACjB/V5r06239 rogid:Jl0eRKrcRF0Blr+KcjsW5mWaBaU6239 intact-crc:06700C2264ECE515|rigid:rBskYHONSpWTTq3jZ7VSd+v70jU false sufficient binding region:986-1041 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20502 uniprotkb:G4S034 intact:EBI-322047|ensemblmetazoa:F47B10.2.1 intact:EBI-6535822|ensemblmetazoa:K10B3.10a.1 psi-mi:huth1_caeel(display_long)|uniprotkb:haly-1(gene name)|psi-mi:haly-1(display_short)|uniprotkb:F47B10.2(orf name) psi-mi:g4s034_caeel(display_long)|uniprotkb:K10B3.10(orf name)|uniprotkb:spc-1(gene name)|psi-mi:spc-1(display_short)|uniprotkb:CELE_K10B3.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535865|imex:IM-18681-346 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509820.1|wormbase:F47B10.2|reactome:R-CEL-70921|ensemblmetazoa:F47B10.2.1(transcript)|ensemblmetazoa:WBGene00009813(gene)|go:"GO:0004397"(histidine ammonia-lyase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006548"(histidine catabolic process)|go:"GO:0016841"(ammonia-lyase activity)|go:"GO:0019556"(histidine catabolic process to glutamate and formamide)|go:"GO:0019557"(histidine catabolic process to glutamate and formate)|go:"GO:0055069"(zinc ion homeostasis)|go:"GO:1990359"(stress response to zinc ion)|interpro:IPR001106(Phenylalanine/histidine ammonia-lyase)|interpro:IPR005921(Histidine ammonia-lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR021922|interpro:IPR022313|interpro:IPR024083|dip:DIP-27218N|uniprotkb:Q20502(identity)|wormbase:WBGene00009813(identity) ensemblmetazoa:K10B3.10a.1(transcript)|ensemblmetazoa:WBGene00004951(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051693"(actin filament capping)|interpro:IPR035825|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|wormbase:K10B3.10a|interpro:IPR018159|interpro:IPR018247|refseq:NP_001256999.1|interpro:IPR036028|uniprotkb:G4S034(identity)|wormbase:WBGene00004951(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DLmqFMQ42XX9heCd3pqz8FQXznk6239 rogid:98NuGykSfInnIVkxQiACjB/V5r06239 intact-crc:727CB113E2D96191|rigid:kt/qxRuR82PIR2mT/7xFLCJy+Tw false - sufficient binding region:986-1041 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4S034 uniprotkb:Q09442 intact:EBI-6535822|ensemblmetazoa:K10B3.10a.1 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 psi-mi:g4s034_caeel(display_long)|uniprotkb:K10B3.10(orf name)|uniprotkb:spc-1(gene name)|psi-mi:spc-1(display_short)|uniprotkb:CELE_K10B3.10(orf name) psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535835|imex:IM-18681-344 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K10B3.10a.1(transcript)|ensemblmetazoa:WBGene00004951(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051693"(actin filament capping)|interpro:IPR035825|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|wormbase:K10B3.10a|interpro:IPR018159|interpro:IPR018247|refseq:NP_001256999.1|interpro:IPR036028|uniprotkb:G4S034(identity)|wormbase:WBGene00004951(identity) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:98NuGykSfInnIVkxQiACjB/V5r06239 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 intact-crc:A5BE9CF30C5607B1|rigid:nHrVh6kmi7yn2oumblzztlWcVx0 false sufficient binding region:986-1041 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4S034 uniprotkb:Q19905 intact:EBI-6535822|ensemblmetazoa:K10B3.10a.1 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 psi-mi:g4s034_caeel(display_long)|uniprotkb:K10B3.10(orf name)|uniprotkb:spc-1(gene name)|psi-mi:spc-1(display_short)|uniprotkb:CELE_K10B3.10(orf name) psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535850|imex:IM-18681-345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K10B3.10a.1(transcript)|ensemblmetazoa:WBGene00004951(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051693"(actin filament capping)|interpro:IPR035825|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|wormbase:K10B3.10a|interpro:IPR018159|interpro:IPR018247|refseq:NP_001256999.1|interpro:IPR036028|uniprotkb:G4S034(identity)|wormbase:WBGene00004951(identity) refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N|uniprotkb:Q19905(identity)|wormbase:WBGene00005022(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:98NuGykSfInnIVkxQiACjB/V5r06239 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 intact-crc:E97F7BF3E7ACA72F|rigid:nykAUDuy9EvL/h1zfNJnqy/fSuY false sufficient binding region:986-1041 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4S034 uniprotkb:O01900 intact:EBI-6535822|ensemblmetazoa:K10B3.10a.1 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 psi-mi:g4s034_caeel(display_long)|uniprotkb:K10B3.10(orf name)|uniprotkb:spc-1(gene name)|psi-mi:spc-1(display_short)|uniprotkb:CELE_K10B3.10(orf name) psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535897|imex:IM-18681-348 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K10B3.10a.1(transcript)|ensemblmetazoa:WBGene00004951(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051693"(actin filament capping)|interpro:IPR035825|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|wormbase:K10B3.10a|interpro:IPR018159|interpro:IPR018247|refseq:NP_001256999.1|interpro:IPR036028|uniprotkb:G4S034(identity)|wormbase:WBGene00004951(identity) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:98NuGykSfInnIVkxQiACjB/V5r06239 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 intact-crc:DC9EA44DCE2C2A98|rigid:9j9bgvFQsRTi0BgTQ2j1PwkpWus false sufficient binding region:986-1041 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GPA4 uniprotkb:G4S034 intact:EBI-6535884|ensemblmetazoa:F48E3.9.1|uniprotkb:G4RTT5 intact:EBI-6535822|ensemblmetazoa:K10B3.10a.1 psi-mi:q9gpa4_caeel(display_long)|uniprotkb:CELE_F48E3.9(orf name)|uniprotkb:F48E3.9(orf name) psi-mi:g4s034_caeel(display_long)|uniprotkb:K10B3.10(orf name)|uniprotkb:spc-1(gene name)|psi-mi:spc-1(display_short)|uniprotkb:CELE_K10B3.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535880|imex:IM-18681-347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F48E3.9.1(transcript)|ensemblmetazoa:WBGene00018608(gene)|refseq:NP_509264.3|wormbase:F48E3.9|uniprotkb:Q9GPA4(identity)|wormbase:WBGene00018608(identity) ensemblmetazoa:K10B3.10a.1(transcript)|ensemblmetazoa:WBGene00004951(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051693"(actin filament capping)|interpro:IPR035825|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|wormbase:K10B3.10a|interpro:IPR018159|interpro:IPR018247|refseq:NP_001256999.1|interpro:IPR036028|uniprotkb:G4S034(identity)|wormbase:WBGene00004951(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 35|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:HMaTpKdGVV+8j1L8Kb+ngOfgyUs6239 rogid:98NuGykSfInnIVkxQiACjB/V5r06239 intact-crc:A2BADD2AE2748A73|rigid:7JhsyMHy5aSSlT+rC5AKDHt97vA false - sufficient binding region:986-1041 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4S034 uniprotkb:Q9BKP3 intact:EBI-6535822|ensemblmetazoa:K10B3.10a.1 intact:EBI-6532905|ensemblmetazoa:H19M22.2c.1 psi-mi:g4s034_caeel(display_long)|uniprotkb:K10B3.10(orf name)|uniprotkb:spc-1(gene name)|psi-mi:spc-1(display_short)|uniprotkb:CELE_K10B3.10(orf name) psi-mi:q9bkp3_caeel(display_long)|uniprotkb:H19M22.2(orf name)|uniprotkb:let-805(gene name)|psi-mi:let-805(display_short)|uniprotkb:CELE_H19M22.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535912|imex:IM-18681-349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K10B3.10a.1(transcript)|ensemblmetazoa:WBGene00004951(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051693"(actin filament capping)|interpro:IPR035825|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|wormbase:K10B3.10a|interpro:IPR018159|interpro:IPR018247|refseq:NP_001256999.1|interpro:IPR036028|uniprotkb:G4S034(identity)|wormbase:WBGene00004951(identity) ensemblmetazoa:H19M22.2c.1(transcript)|ensemblmetazoa:WBGene00002915(gene)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0043235"(receptor complex)|refseq:NP_001293642.1|wormbase:H19M22.2c|uniprotkb:Q9BKP3(identity)|wormbase:WBGene00002915(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:98NuGykSfInnIVkxQiACjB/V5r06239 rogid:SjkoY4LhauaQpAj37X8Ore+almU6239 intact-crc:A551FACB8250777D|rigid:oBsSXW9/Kj4si76RDq4N074I988 false sufficient binding region:986-1041 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32085 uniprotkb:G4S034 intact:EBI-313377|ensemblmetazoa:T20B12.2.1 intact:EBI-6535822|ensemblmetazoa:K10B3.10a.1 psi-mi:tbp_caeel(display_long)|uniprotkb:tbp-1(gene name)|psi-mi:tbp-1(display_short)|uniprotkb:tbp(gene name synonym)|uniprotkb:T20B12.2(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:g4s034_caeel(display_long)|uniprotkb:K10B3.10(orf name)|uniprotkb:spc-1(gene name)|psi-mi:spc-1(display_short)|uniprotkb:CELE_K10B3.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535927|imex:IM-18681-350 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498635.1|wormbase:T20B12.2|ensemblmetazoa:T20B12.2.1(transcript)|ensemblmetazoa:WBGene00006542(gene)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|go:"GO:0006352"(DNA-templated transcription, initiation)|reactome:R-CEL-6807505|reactome:R-CEL-674695|reactome:R-CEL-73776|reactome:R-CEL-73779|reactome:R-CEL-75953|reactome:R-CEL-76042|reactome:R-CEL-9018519|dip:DIP-26447N|reactome:R-CEL-73772|uniprotkb:P32085(identity)|wormbase:WBGene00006542(identity) ensemblmetazoa:K10B3.10a.1(transcript)|ensemblmetazoa:WBGene00004951(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051693"(actin filament capping)|interpro:IPR035825|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|wormbase:K10B3.10a|interpro:IPR018159|interpro:IPR018247|refseq:NP_001256999.1|interpro:IPR036028|uniprotkb:G4S034(identity)|wormbase:WBGene00004951(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 28|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:o7s313h1WbgESEEeKW35tAqWX2k6239 rogid:98NuGykSfInnIVkxQiACjB/V5r06239 intact-crc:2D3FCC35441FD47E|rigid:Kr5KEJHqeXWxFaNXP89AqwZN6Cs false - sufficient binding region:986-1041 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N582 uniprotkb:G4S034 intact:EBI-315836|uniprotkb:G4RQM4|ensemblmetazoa:Y119C1A.1.1 intact:EBI-6535822|ensemblmetazoa:K10B3.10a.1 psi-mi:q9n582_caeel(display_long)|uniprotkb:Y119C1A.1(orf name)|uniprotkb:CELE_Y119C1A.1(orf name) psi-mi:g4s034_caeel(display_long)|uniprotkb:K10B3.10(orf name)|uniprotkb:spc-1(gene name)|psi-mi:spc-1(display_short)|uniprotkb:CELE_K10B3.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535942|imex:IM-18681-351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491414.3|wormbase:Y119C1A.1|ensemblmetazoa:WBGene00022466(gene)|ensemblmetazoa:Y119C1A.1.1(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|dip:DIP-25664N|uniprotkb:Q9N582(identity)|wormbase:WBGene00022466(identity) ensemblmetazoa:K10B3.10a.1(transcript)|ensemblmetazoa:WBGene00004951(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051693"(actin filament capping)|interpro:IPR035825|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|wormbase:K10B3.10a|interpro:IPR018159|interpro:IPR018247|refseq:NP_001256999.1|interpro:IPR036028|uniprotkb:G4S034(identity)|wormbase:WBGene00004951(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:R1myvfwl3fRTxYXIBadj+zdG1lM6239 rogid:98NuGykSfInnIVkxQiACjB/V5r06239 intact-crc:70844255CCCDF702|rigid:lZ7wyinNy+yoyXRd3sAmc/3kCTI false - sufficient binding region:986-1041 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A8WFL0 uniprotkb:G4S034 intact:EBI-6533929|ensemblmetazoa:ZK381.5b.1 intact:EBI-6535822|ensemblmetazoa:K10B3.10a.1 psi-mi:a8wfl0_caeel(display_long)|uniprotkb:ZK381.5(orf name)|uniprotkb:prkl-1(gene name)|psi-mi:prkl-1(display_short)|uniprotkb:CELE_ZK381.5(orf name) psi-mi:g4s034_caeel(display_long)|uniprotkb:K10B3.10(orf name)|uniprotkb:spc-1(gene name)|psi-mi:spc-1(display_short)|uniprotkb:CELE_K10B3.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535957|imex:IM-18681-352 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00022727(gene)|ensemblmetazoa:ZK381.5b.1(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_741436.2|wormbase:ZK381.5b|uniprotkb:A8WFL0(identity)|wormbase:WBGene00022727(identity) ensemblmetazoa:K10B3.10a.1(transcript)|ensemblmetazoa:WBGene00004951(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051693"(actin filament capping)|interpro:IPR035825|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|wormbase:K10B3.10a|interpro:IPR018159|interpro:IPR018247|refseq:NP_001256999.1|interpro:IPR036028|uniprotkb:G4S034(identity)|wormbase:WBGene00004951(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 18|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:fcmrkFYkH8buNRyUpTMTG+NeuoM6239 rogid:98NuGykSfInnIVkxQiACjB/V5r06239 intact-crc:DC96E635A8151BEF|rigid:PEwpQ0Xc7TBH0iXyX45IA5NxU+A false - sufficient binding region:986-1041 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45233 uniprotkb:Q18501 intact:EBI-330100|ensemblmetazoa:C01G12.1.1 intact:EBI-6535972|ensemblmetazoa:C36E8.4.1 psi-mi:o45233_caeel(display_long)|uniprotkb:C01G12.1(orf name)|uniprotkb:madf-5(gene name)|psi-mi:madf-5(display_short)|uniprotkb:CELE_C01G12.1(orf name) psi-mi:q18501_caeel(display_long)|uniprotkb:CELE_C36E8.4(orf name)|uniprotkb:C36E8.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535974|imex:IM-18681-353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497028.1|wormbase:C01G12.1|dip:DIP-27356N|ensemblmetazoa:C01G12.1.1(transcript)|ensemblmetazoa:WBGene00007242(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR004210(BESS motif)|interpro:IPR006578(MADF)|interpro:IPR039353|uniprotkb:O45233(identity)|wormbase:WBGene00007242(identity) ensemblmetazoa:C36E8.4.1(transcript)|ensemblmetazoa:WBGene00007983(gene)|interpro:IPR027267|interpro:IPR031160|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_497805.2|wormbase:C36E8.4|interpro:IPR036028|uniprotkb:Q18501(identity)|wormbase:WBGene00007983(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Jl0eRKrcRF0Blr+KcjsW5mWaBaU6239 rogid:7ad27IrJILlSTyYLMCV6AMEp1IA6239 intact-crc:0EC131408D518BB5|rigid:MWNoCqFhuEyHgGqs617x3RtKhAc false - sufficient binding region:484-548 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32085 uniprotkb:Q18501 intact:EBI-313377|ensemblmetazoa:T20B12.2.1 intact:EBI-6535972|ensemblmetazoa:C36E8.4.1 psi-mi:tbp_caeel(display_long)|uniprotkb:tbp-1(gene name)|psi-mi:tbp-1(display_short)|uniprotkb:tbp(gene name synonym)|uniprotkb:T20B12.2(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:q18501_caeel(display_long)|uniprotkb:CELE_C36E8.4(orf name)|uniprotkb:C36E8.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6535990|imex:IM-18681-354 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498635.1|wormbase:T20B12.2|ensemblmetazoa:T20B12.2.1(transcript)|ensemblmetazoa:WBGene00006542(gene)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|go:"GO:0006352"(DNA-templated transcription, initiation)|reactome:R-CEL-6807505|reactome:R-CEL-674695|reactome:R-CEL-73776|reactome:R-CEL-73779|reactome:R-CEL-75953|reactome:R-CEL-76042|reactome:R-CEL-9018519|dip:DIP-26447N|reactome:R-CEL-73772|uniprotkb:P32085(identity)|wormbase:WBGene00006542(identity) ensemblmetazoa:C36E8.4.1(transcript)|ensemblmetazoa:WBGene00007983(gene)|interpro:IPR027267|interpro:IPR031160|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_497805.2|wormbase:C36E8.4|interpro:IPR036028|uniprotkb:Q18501(identity)|wormbase:WBGene00007983(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:o7s313h1WbgESEEeKW35tAqWX2k6239 rogid:7ad27IrJILlSTyYLMCV6AMEp1IA6239 intact-crc:3E973A2064B0A141|rigid:kKuhI/mNC5z4+tMrWZN9M77b0e0 false - sufficient binding region:484-548 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E3W735 uniprotkb:O45233 intact:EBI-6536005|ensemblmetazoa:K11E4.4b.1 intact:EBI-330100|ensemblmetazoa:C01G12.1.1 psi-mi:e3w735_caeel(display_long)|uniprotkb:K11E4.4(orf name)|uniprotkb:pix-1(gene name)|psi-mi:pix-1(display_short)|uniprotkb:CELE_K11E4.4(orf name) psi-mi:o45233_caeel(display_long)|uniprotkb:C01G12.1(orf name)|uniprotkb:madf-5(gene name)|psi-mi:madf-5(display_short)|uniprotkb:CELE_C01G12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536007|imex:IM-18681-355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040039"(inductive cell migration)|ensemblmetazoa:K11E4.4b.1(transcript)|ensemblmetazoa:WBGene00010776(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0016301"(kinase activity)|go:"GO:0030056"(hemidesmosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001257228.1|wormbase:K11E4.4b|interpro:IPR035899|interpro:IPR036028|uniprotkb:E3W735(identity)|wormbase:WBGene00010776(identity) refseq:NP_497028.1|wormbase:C01G12.1|dip:DIP-27356N|ensemblmetazoa:C01G12.1.1(transcript)|ensemblmetazoa:WBGene00007242(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR004210(BESS motif)|interpro:IPR006578(MADF)|interpro:IPR039353|uniprotkb:O45233(identity)|wormbase:WBGene00007242(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ZkXL8YaZ0pnMS0ZZJIQv3V//uSE6239 rogid:Jl0eRKrcRF0Blr+KcjsW5mWaBaU6239 intact-crc:2C6A5DC967A7962C|rigid:NSZOgt6xNcIDbKic6aWzKRJ+QU4 false sufficient binding region:188-243 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01900 uniprotkb:E3W735 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 intact:EBI-6536005|ensemblmetazoa:K11E4.4b.1 psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:e3w735_caeel(display_long)|uniprotkb:K11E4.4(orf name)|uniprotkb:pix-1(gene name)|psi-mi:pix-1(display_short)|uniprotkb:CELE_K11E4.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536037|imex:IM-18681-357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040039"(inductive cell migration)|ensemblmetazoa:K11E4.4b.1(transcript)|ensemblmetazoa:WBGene00010776(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0016301"(kinase activity)|go:"GO:0030056"(hemidesmosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001257228.1|wormbase:K11E4.4b|interpro:IPR035899|interpro:IPR036028|uniprotkb:E3W735(identity)|wormbase:WBGene00010776(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 rogid:ZkXL8YaZ0pnMS0ZZJIQv3V//uSE6239 intact-crc:BFE0AA9CE8EC4021|rigid:g/6GAjdUsvB24c8/3vYJDx38pX0 false - sufficient binding region:188-243 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:E3W735 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-6536005|ensemblmetazoa:K11E4.4b.1 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:e3w735_caeel(display_long)|uniprotkb:K11E4.4(orf name)|uniprotkb:pix-1(gene name)|psi-mi:pix-1(display_short)|uniprotkb:CELE_K11E4.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536022|imex:IM-18681-356 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040039"(inductive cell migration)|ensemblmetazoa:K11E4.4b.1(transcript)|ensemblmetazoa:WBGene00010776(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0016301"(kinase activity)|go:"GO:0030056"(hemidesmosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001257228.1|wormbase:K11E4.4b|interpro:IPR035899|interpro:IPR036028|uniprotkb:E3W735(identity)|wormbase:WBGene00010776(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:ZkXL8YaZ0pnMS0ZZJIQv3V//uSE6239 intact-crc:9E7BD77E5683AABC|rigid:jmzH0RRdDVuIO4EXz7waicQcjEY false - sufficient binding region:188-243 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E3W735 uniprotkb:P32085 intact:EBI-6536005|ensemblmetazoa:K11E4.4b.1 intact:EBI-313377|ensemblmetazoa:T20B12.2.1 psi-mi:e3w735_caeel(display_long)|uniprotkb:K11E4.4(orf name)|uniprotkb:pix-1(gene name)|psi-mi:pix-1(display_short)|uniprotkb:CELE_K11E4.4(orf name) psi-mi:tbp_caeel(display_long)|uniprotkb:tbp-1(gene name)|psi-mi:tbp-1(display_short)|uniprotkb:tbp(gene name synonym)|uniprotkb:T20B12.2(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536052|imex:IM-18681-358 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040039"(inductive cell migration)|ensemblmetazoa:K11E4.4b.1(transcript)|ensemblmetazoa:WBGene00010776(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0016301"(kinase activity)|go:"GO:0030056"(hemidesmosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001257228.1|wormbase:K11E4.4b|interpro:IPR035899|interpro:IPR036028|uniprotkb:E3W735(identity)|wormbase:WBGene00010776(identity) refseq:NP_498635.1|wormbase:T20B12.2|ensemblmetazoa:T20B12.2.1(transcript)|ensemblmetazoa:WBGene00006542(gene)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|go:"GO:0006352"(DNA-templated transcription, initiation)|reactome:R-CEL-6807505|reactome:R-CEL-674695|reactome:R-CEL-73776|reactome:R-CEL-73779|reactome:R-CEL-75953|reactome:R-CEL-76042|reactome:R-CEL-9018519|dip:DIP-26447N|reactome:R-CEL-73772|uniprotkb:P32085(identity)|wormbase:WBGene00006542(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 18|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ZkXL8YaZ0pnMS0ZZJIQv3V//uSE6239 rogid:o7s313h1WbgESEEeKW35tAqWX2k6239 intact-crc:B40B4AA204554B18|rigid:UMU1rCXJAURzwPQWiPz1HfmJWEA false sufficient binding region:188-243 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XQ1 uniprotkb:E3W735 intact:EBI-313459|ensemblmetazoa:Y39G10AR.17.1 intact:EBI-6536005|ensemblmetazoa:K11E4.4b.1 psi-mi:sydn_caeel(display_long)|uniprotkb:Y39G10AR.17(orf name)|uniprotkb:sydn-1(gene name)|psi-mi:sydn-1(display_short) psi-mi:e3w735_caeel(display_long)|uniprotkb:K11E4.4(orf name)|uniprotkb:pix-1(gene name)|psi-mi:pix-1(display_short)|uniprotkb:CELE_K11E4.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536067|imex:IM-18681-359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y39G10AR.17|ensemblmetazoa:WBGene00021473(gene)|ensemblmetazoa:Y39G10AR.17.1(transcript)|go:"GO:0016607"(nuclear speck)|go:"GO:0006397"(mRNA processing)|mint:Q95XQ1|refseq:NP_490969.4|dip:DIP-24383N|uniprotkb:Q95XQ1(identity)|wormbase:WBGene00021473(identity) go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040039"(inductive cell migration)|ensemblmetazoa:K11E4.4b.1(transcript)|ensemblmetazoa:WBGene00010776(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0016301"(kinase activity)|go:"GO:0030056"(hemidesmosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001257228.1|wormbase:K11E4.4b|interpro:IPR035899|interpro:IPR036028|uniprotkb:E3W735(identity)|wormbase:WBGene00010776(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:aoAMOcrfpjxDHg+8smQRjOT8yz46239 rogid:ZkXL8YaZ0pnMS0ZZJIQv3V//uSE6239 intact-crc:41DCD2557F3A0158|rigid:X2zYNuJEyYtVNyMHPHszhsQ4MW0 false - sufficient binding region:188-243 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EG53 uniprotkb:E3W735 intact:EBI-6536086|ensemblmetazoa:Y50D4C.1a.1 intact:EBI-6536005|ensemblmetazoa:K11E4.4b.1 psi-mi:g5eg53_caeel(display_long)|uniprotkb:Y50D4C.1(orf name)|uniprotkb:unc-34(gene name)|psi-mi:unc-34(display_short)|uniprotkb:CELE_Y50D4C.1(orf name) psi-mi:e3w735_caeel(display_long)|uniprotkb:K11E4.4(orf name)|uniprotkb:pix-1(gene name)|psi-mi:pix-1(display_short)|uniprotkb:CELE_K11E4.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536082|imex:IM-18681-360 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006770(gene)|ensemblmetazoa:Y50D4C.1a.1(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032433"(filopodium tip)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040017"(positive regulation of locomotion)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_503360.4|wormbase:Y50D4C.1a|reactome:R-CEL-446353|uniprotkb:G5EG53(identity)|wormbase:WBGene00006770(identity) go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040039"(inductive cell migration)|ensemblmetazoa:K11E4.4b.1(transcript)|ensemblmetazoa:WBGene00010776(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0016301"(kinase activity)|go:"GO:0030056"(hemidesmosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001257228.1|wormbase:K11E4.4b|interpro:IPR035899|interpro:IPR036028|uniprotkb:E3W735(identity)|wormbase:WBGene00010776(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:YztDB2tZk9JFqV25NJfYSwPW5Xo6239 rogid:ZkXL8YaZ0pnMS0ZZJIQv3V//uSE6239 intact-crc:8B51DB5D92A401C9|rigid:SNac3oHqWHm9mcsqHXGdkfA8d5o false - sufficient binding region:188-243 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:O62011 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-6456084|ensemblmetazoa:B0379.3a.1 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:o62011_caeel(display_long)|uniprotkb:B0379.3(orf name)|uniprotkb:mut-16(gene name)|psi-mi:mut-16(display_short)|uniprotkb:CELE_B0379.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536099|imex:IM-18681-361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) ensemblmetazoa:B0379.3a.1(transcript)|ensemblmetazoa:WBGene00003508(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016246"(RNA interference)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:1990633"(mutator focus)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_492660.3|wormbase:B0379.3a|uniprotkb:O62011(identity)|wormbase:WBGene00003508(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:gMuLdz+fFz3VGJe/rR1zhKWvqIQ6239 intact-crc:6B296A7A6743E6E0|rigid:O1uHe+clcD5YSdYpkqbefROFVGI false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:G5EDW2 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-6536114|ensemblmetazoa:B0457.1a.1|uniprotkb:G5EEH7|uniprotkb:Q7JM97 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:lplt1_caeel(display_long)|uniprotkb:lat-1(gene name)|psi-mi:lat-1(display_short)|uniprotkb:B0457.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536116|imex:IM-18681-362 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) ensemblmetazoa:B0457.1a.1(transcript)|ensemblmetazoa:WBGene00002251(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0097264"(self proteolysis)|interpro:IPR043159|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR017981|refseq:NP_495894.1|wormbase:B0457.1a|wormbase:B0457.1b|wormbase:B0457.1c|interpro:IPR032471|refseq:NP_001021897.1|refseq:NP_871949.1|interpro:IPR036445|uniprotkb:G5EDW2(identity)|wormbase:WBGene00002251(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 19|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:n+W9suq+p4Tga/9psIdazzYhZGM6239 intact-crc:6159C9F28B4B6B0B|rigid:86x9kfn+LQFgf0lTBpBehN5Snik false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18241 uniprotkb:P03949 intact:EBI-313204|uniprotkb:Q18243|ensemblmetazoa:C27B7.4a.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:q18241_caeel(display_long)|uniprotkb:rad-26(gene name)|psi-mi:rad-26(display_short)|uniprotkb:C27B7.4(orf name)|uniprotkb:CELE_C27B7.4(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536146|imex:IM-18681-364 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501545.1|ensemblmetazoa:C27B7.4a.1(transcript)|ensemblmetazoa:WBGene00007761(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|interpro:IPR044573|go:"GO:0005524"(ATP binding)|interpro:IPR044574|dip:DIP-26472N|wormbase:C27B7.4a|uniprotkb:Q18241(identity)|wormbase:WBGene00007761(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:5WdWyL8X39h3//iC/Qw+n6rZkEw6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:EB9667626B0EC8DF|rigid:HqFWYLkCjLKqgB+NTgF1XNWQWtU false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:Q09442 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536131|imex:IM-18681-363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 intact-crc:1211BC4296FA2088|rigid:M2PRrBhUg2doTTRFG3oAs9pcUtY false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:Q18529 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-314884|ensemblmetazoa:C39D10.7.2|ensemblmetazoa:C39D10.7.1 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:q18529_caeel(display_long)|uniprotkb:C39D10.7(orf name)|uniprotkb:CELE_C39D10.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536176|imex:IM-18681-366 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) refseq:NP_509334.3|wormbase:C39D10.7|ensemblmetazoa:C39D10.7.2(transcript)|ensemblmetazoa:WBGene00016534(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008061"(chitin binding)|interpro:IPR002557(Chitin binding protein, peritrophin-A)|interpro:IPR036508|ensemblmetazoa:C39D10.7.1(transcript)|dip:DIP-27006N|uniprotkb:Q18529(identity)|wormbase:WBGene00016534(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:gnU6jSkV05zYFXSGRFYUIcPLW5Q6239 intact-crc:0DE6ADD77540C5EA|rigid:t5HsLbJFeaeGS24vBYbJUFzY2Vc false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18320 uniprotkb:P03949 intact:EBI-327120|ensemblmetazoa:C30B5.1.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:q18320_caeel(display_long)|uniprotkb:szy-4(gene name)|psi-mi:szy-4(display_short)|uniprotkb:CELE_C30B5.1(orf name)|uniprotkb:C30B5.1(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536161|imex:IM-18681-365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495240.3|wormbase:C30B5.1|ensemblmetazoa:C30B5.1.1(transcript)|ensemblmetazoa:WBGene00077732(gene)|go:"GO:0010824"(regulation of centrosome duplication)|dip:DIP-26627N|uniprotkb:Q18320(identity)|wormbase:WBGene00016243(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:6IqpSSIKuKFLXLTuaEL2dI5mqF06239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:CF4C00A9F719BC30|rigid:a+Grg3JQLCa46dEt10FKflFNHuo false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18953 uniprotkb:P03949 intact:EBI-318539|uniprotkb:B5U8M4|ensemblmetazoa:D1054.13a.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:spcs_caeel(display_long)|uniprotkb:secs-1(gene name)|psi-mi:secs-1(display_short)|uniprotkb:D1054.13(orf name)|uniprotkb:"Selenocysteinyl-tRNA(Sec) synthase"(gene name synonym)|uniprotkb:"Sep-tRNA:Sec-tRNA synthase"(gene name synonym)|uniprotkb:UGA suppressor tRNA-associated protein homolog(gene name synonym)|uniprotkb:Selenocysteine synthase(gene name synonym) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536191|imex:IM-18681-367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129887.1|refseq:NP_505761.1|wormbase:D1054.13a|wormbase:D1054.13b|ensemblmetazoa:D1054.13a.1(transcript)|ensemblmetazoa:WBGene00008379(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0001514"(selenocysteine incorporation)|go:"GO:0005737"(cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process")|go:"GO:0098621"(phosphoseryl-selenocysteinyl-tRNA selenium transferase activity)|interpro:IPR008829(Soluble liver antigen/liver pancreas antigen)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019872|mint:Q18953|dip:DIP-26886N|uniprotkb:Q18953(identity)|wormbase:WBGene00008379(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 33|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:J5TkQ+CIecgTuXqiIG7tsdEntlE6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:32B42C82A296ACD1|rigid:Dz9FCKQTkPQv/G4S+LqRjDouaZQ false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19749 uniprotkb:P03949 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536206|imex:IM-18681-368 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N|uniprotkb:Q19749(identity)|wormbase:WBGene00009082(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:406FB1C134926FC2|rigid:YKMQIs33Kk/zzIIHP9vvsmjFMX0 false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B3GWA0 uniprotkb:P03949 intact:EBI-6534207|ensemblmetazoa:F25B5.7c.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:b3gwa0_caeel(display_long)|uniprotkb:nono-1(gene name)|psi-mi:nono-1(display_short)|uniprotkb:CELE_F25B5.7(orf name)|uniprotkb:F25B5.7(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536221|imex:IM-18681-369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F25B5.7c.1(transcript)|ensemblmetazoa:WBGene00017778(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR012975(NOPS)|refseq:NP_498296.3|wormbase:F25B5.7c|uniprotkb:B3GWA0(identity)|wormbase:WBGene00017778(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lWJ7KO5EiJ5HtKHW+fGsAOn5RhU6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:091A5451CC64383B|rigid:R7RZccLXE7u+gQJgohS5hBg0dKU false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:E3W743 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536236|imex:IM-18681-370 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 intact-crc:5213E23546CE5674|rigid:vFMyFZ/QKyV9KT2POGrVq7du1Qc false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A5JYT7 uniprotkb:P03949 intact:EBI-6536255|ensemblmetazoa:F32D8.7b.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:a5jyt7_caeel(display_long)|uniprotkb:CELE_F32D8.7(orf name)|uniprotkb:F32D8.7(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536251|imex:IM-18681-371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32D8.7b.1(transcript)|ensemblmetazoa:WBGene00009331(gene)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|refseq:NP_001122937.1|wormbase:F32D8.7b|interpro:IPR036880|uniprotkb:A5JYT7(identity)|wormbase:WBGene00009331(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 18|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:PQPBy2+5kZase8AL+5EcdwnU22k6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:41CB368828B89B27|rigid:A382VVbJBwHzufalxBvvSH8GsW4 false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:O01900 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536283|imex:IM-18681-373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 intact-crc:29751878BAB8DE5E|rigid:pnL4t36CGjq+5xb78v3c86hwtKI false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECW9 uniprotkb:P03949 intact:EBI-315316|ensemblmetazoa:F46F6.1a.1|ensemblmetazoa:F46F6.1a.2 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:g5ecw9_caeel(display_long)|uniprotkb:rme-4(gene name)|psi-mi:rme-4(display_short)|uniprotkb:F46F6.1(orf name)|uniprotkb:CELE_F46F6.1(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536268|imex:IM-18681-372 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q20473(uniprot-removed-ac)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|refseq:NP_509739.1|wormbase:F46F6.1a|mint:G5ECW9|ensemblmetazoa:F46F6.1a.1(transcript)|ensemblmetazoa:F46F6.1a.2(transcript)|ensemblmetazoa:WBGene00004375(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR043153|interpro:IPR040032|interpro:IPR037516|uniprotkb:G5ECW9(identity)|wormbase:WBGene00004375(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:3FE5ecvvghPRxJTDrlb8Ij9Vzx46239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:A9B3EB7FFD7A820A|rigid:CBNdWAgPzmnJYl0Z+zcnYzVRYR4 false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09345 uniprotkb:P03949 intact:EBI-2006279|ensemblmetazoa:R144.2a.1|ensemblmetazoa:R144.2a.2 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:pcf11_caeel(display_long)|uniprotkb:R144.2(orf name)|uniprotkb:pcf-11(gene name)|psi-mi:pcf-11(display_short) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536313|imex:IM-18681-375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498068.1|wormbase:R144.2a|interpro:IPR008942(ENTH/VHS)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|reactome:R-CEL-6807505|reactome:R-CEL-73856|ensemblmetazoa:R144.2a.1(transcript)|ensemblmetazoa:R144.2a.2(transcript)|ensemblmetazoa:WBGene00020092(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|uniprotkb:Q09345(identity)|wormbase:WBGene00020092(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:XTyRR+k9dN5uoxwUXnAuM34SSUA6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:1B560F09F37081B3|rigid:AcLWdoNIIsZT0U2BBTmqT8c069g false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6BEV5 uniprotkb:P03949 intact:EBI-2002318|intact:EBI-2923757|intact:EBI-2924015|ensemblmetazoa:R06F6.12.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:yrmc_caeel(display_long)|uniprotkb:R06F6.12(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536298|imex:IM-18681-374 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022277.1|wormbase:R06F6.12|ensemblmetazoa:R06F6.12.1(transcript)|ensemblmetazoa:WBGene00023418(gene)|uniprotkb:Q6BEV5(identity)|wormbase:WBGene00023418(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 18|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:jP7TZCce2muoY78Ruk/qCSELK5M6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:B95B86A27E9FDE2C|rigid:pVKFy2ztwqjxMV4A943IGR9sdG8 false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34568 uniprotkb:P03949 intact:EBI-327767|uniprotkb:Q5CZ49|ensemblmetazoa:T16H12.5a.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:bat43_caeel(display_long)|uniprotkb:T16H12.5(orf name)|uniprotkb:HIB homolog(gene name synonym)|uniprotkb:bath-43(gene name)|psi-mi:bath-43(display_short) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536343|imex:IM-18681-377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022764.1|refseq:NP_001022765.1|wormbase:T16H12.5a|wormbase:T16H12.5b|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|reactome:R-CEL-5632684|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|ensemblmetazoa:T16H12.5a.1(transcript)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|ensemblmetazoa:WBGene00011815(gene)|go:"GO:0005634"(nucleus)|uniprotkb:P34568(identity)|wormbase:WBGene00011815(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:jdL1h8z7Z9QycJYQHIVzF66EkL86239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:BA91C5462432ECA9|rigid:xRPC5J87RXdUwJ2mjIIW8OP1Nr4 false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:P03949 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536328|imex:IM-18681-376 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 20|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:FC1CC31CF12D4E02|rigid:8fJhiAeC+Q9DsvmC+nuuCmXG1TA false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:P91820 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536358|imex:IM-18681-378 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N|uniprotkb:P91820(identity)|wormbase:WBGene00003083(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 intact-crc:1500DCC7F7317FD6|rigid:1Rn6rYy29wk2IwCPsUwy999B3c8 false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U304 uniprotkb:P03949 intact:EBI-329038|ensemblmetazoa:Y106G6D.7.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:q9u304_caeel(display_long)|uniprotkb:rbm-12(gene name)|psi-mi:rbm-12(display_short)|uniprotkb:CELE_Y106G6D.7(orf name)|uniprotkb:Y106G6D.7(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536373|imex:IM-18681-379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492671.1|wormbase:Y106G6D.7|dip:DIP-26480N|ensemblmetazoa:WBGene00013703(gene)|ensemblmetazoa:Y106G6D.7.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-CEL-72163|uniprotkb:Q9U304(identity)|wormbase:WBGene00013703(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:/8MJkmHgCyjvgK0ZmDnklHVfJrw6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:1A7BFE51ECAA981E|rigid:YqvixiN9GpG93dC27BMnXXrZ604 false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:Q8T870 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-6536420|ensemblmetazoa:Y69A2AR.30b.1|ensemblmetazoa:Y69A2AR.30b.2 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:q8t870_caeel(display_long)|uniprotkb:Y69A2AR.30(orf name)|uniprotkb:mdf-2(gene name)|psi-mi:mdf-2(display_short)|uniprotkb:CELE_Y69A2AR.30(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536422|imex:IM-18681-382 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) ensemblmetazoa:WBGene00003161(gene)|ensemblmetazoa:Y69A2AR.30b.1(transcript)|ensemblmetazoa:Y69A2AR.30b.2(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0034059"(response to anoxia)|go:"GO:0045120"(pronucleus)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|refseq:NP_741342.2|wormbase:Y69A2AR.30b|interpro:IPR036570|uniprotkb:Q8T870(identity)|wormbase:WBGene00003161(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:1Ilg+XP9mCp3+U6qt6ErCDwZwjc6239 intact-crc:737FC637E2A48A0B|rigid:rDNyx+R7lCNB5Vjt2/YBBpf8QOk false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:P03949 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536405|imex:IM-18681-381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:01046D6E0716E325|rigid:Corif4Vwr0s7Uf42DZs1k1LrUgs false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:Q8I4E2 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-4325777|uniprotkb:D3NQ98|uniprotkb:J7SA60|uniprotkb:Q8I4E1|uniprotkb:Q9XXG2|uniprotkb:Q9XXG3|ensemblmetazoa:Y37A1B.2c.1 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:lst4_caeel(display_long)|uniprotkb:lst-4(gene name)|psi-mi:lst-4(display_short)|uniprotkb:Lateral signaling target protein 4(gene name synonym)|uniprotkb:Y37A1B.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536390|imex:IM-18681-380 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) interpro:IPR036871|interpro:IPR027267|interpro:IPR036028|wormbase:Y37A1B.2d|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|reactome:R-CEL-8856828|refseq:NP_502693.2|wormbase:Y37A1B.2a|wormbase:Y37A1B.2b|wormbase:Y37A1B.2c|wormbase:Y37A1B.2e|wormbase:Y37A1B.2f|refseq:NP_001255779.1|refseq:NP_001263811.1|refseq:NP_502694.1|refseq:NP_502695.2|refseq:NP_872090.1|reactome:R-CEL-432722|go:"GO:0032009"(early phagosome)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045335"(phagocytic vesicle)|ensemblmetazoa:WBGene00003086(gene)|ensemblmetazoa:Y37A1B.2c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0090389"(phagosome-lysosome fusion involved in apoptotic cell clearance)|go:"GO:0097194"(execution phase of apoptosis) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:NqGhrxQdIIT2DDOgu+/swsZFniQ6239 intact-crc:60A3AFEF192BB87A|rigid:WRS0Jkbd87Xc7hsQwR7aen2dM10 false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:Q4VNJ8 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-2918529 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536437|imex:IM-18681-383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 intact-crc:C4B7BC075A69FF48|rigid:6Ov/6Knz+KPw9xCpa0JHUyekKK0 false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:Q9BIF4 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536452|imex:IM-18681-384 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 22|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/09 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 intact-crc:2DA2DCC0A1FF5BEC|rigid:tkBtUmE/Kc/aqMw4sii+v7wdgt0 false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBH3 uniprotkb:Q09442 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536469|imex:IM-18681-385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 intact-crc:AAB138A488093F26|rigid:KdI2npIOl9UQYAUffhlDbsrdKI4 false sufficient binding region:826-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECW9 uniprotkb:G5EBH3 intact:EBI-315316|ensemblmetazoa:F46F6.1a.1|ensemblmetazoa:F46F6.1a.2 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 psi-mi:g5ecw9_caeel(display_long)|uniprotkb:rme-4(gene name)|psi-mi:rme-4(display_short)|uniprotkb:F46F6.1(orf name)|uniprotkb:CELE_F46F6.1(orf name) psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536484|imex:IM-18681-386 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q20473(uniprot-removed-ac)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|refseq:NP_509739.1|wormbase:F46F6.1a|mint:G5ECW9|ensemblmetazoa:F46F6.1a.1(transcript)|ensemblmetazoa:F46F6.1a.2(transcript)|ensemblmetazoa:WBGene00004375(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR043153|interpro:IPR040032|interpro:IPR037516|uniprotkb:G5ECW9(identity)|wormbase:WBGene00004375(identity) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 86|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:3FE5ecvvghPRxJTDrlb8Ij9Vzx46239 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 intact-crc:1D55FF662F07C55A|rigid:IwGnZVqC1B18NgIzOfJVMFgrM5k false - sufficient binding region:826-879 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBH3 uniprotkb:Q8I4H7 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 intact:EBI-6536499|ensemblmetazoa:K02C4.5.1 psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:q8i4h7_caeel(display_long)|uniprotkb:CELE_K02C4.5(orf name)|uniprotkb:K02C4.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536501|imex:IM-18681-387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) ensemblmetazoa:K02C4.5.1(transcript)|ensemblmetazoa:WBGene00010503(gene)|refseq:NP_495695.2|wormbase:K02C4.5|uniprotkb:Q8I4H7(identity)|wormbase:WBGene00010503(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 rogid:/psCM8S6y04pL8WA8ShGIWUwm4Q6239 intact-crc:D3735CA2E86944E5|rigid:vrg9Gz9RydPYjkSAA1Iw7ItRXaQ false sufficient binding region:826-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBH3 uniprotkb:E7EM33 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 intact:EBI-6535096|ensemblmetazoa:K11E8.1q.1 psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:e7em33_caeel(display_long)|uniprotkb:K11E8.1(orf name)|uniprotkb:unc-43(gene name)|psi-mi:unc-43(display_short)|uniprotkb:CELE_K11E8.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536516|imex:IM-18681-388 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) ensemblmetazoa:K11E8.1q.1(transcript)|ensemblmetazoa:WBGene00006779(gene)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|interpro:IPR032710|refseq:NP_001255483.1|wormbase:K11E8.1q|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|uniprotkb:E7EM33(identity)|wormbase:WBGene00006779(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 rogid:wJ7Mv8XBGds/21oTfrakhpmcoUM6239 intact-crc:5906711CA777949E|rigid:kpRkmegGB+56T/qS8AvqT0OIBZ0 false sufficient binding region:826-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBH3 uniprotkb:Q9XWN1 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 intact:EBI-324865|ensemblmetazoa:Y43F8C.6a.1 psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:q9xwn1_caeel(display_long)|uniprotkb:Y43F8C.6(orf name)|uniprotkb:CELE_Y43F8C.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536546|imex:IM-18681-390 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) refseq:NP_001256880.1|wormbase:Y43F8C.6a|ensemblmetazoa:WBGene00012828(gene)|ensemblmetazoa:Y43F8C.6a.1(transcript)|go:"GO:0016589"(NURF complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR037931|dip:DIP-27198N|uniprotkb:Q9XWN1(identity)|wormbase:WBGene00012828(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 rogid:BnRBxnWaRRWRCAx+LGlNwRaOcOU6239 intact-crc:C3B1A64CBA9E3896|rigid:b7bw2a4lnzta5r/XQ27UMg4oESs false sufficient binding region:826-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBH3 uniprotkb:G5EC72 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536531|imex:IM-18681-389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 28|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:A3A4B8C0F043C7D5|rigid:qbKD39kCWDSOiN560lc1sJNfmYk false sufficient binding region:826-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8I4M6 uniprotkb:Q8MPT2 intact:EBI-6536576|ensemblmetazoa:C31C9.6.1 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:q8i4m6_caeel(display_long)|uniprotkb:CELE_C31C9.6(orf name)|uniprotkb:C31C9.6(orf name) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536578|imex:IM-18681-392 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C31C9.6.1(transcript)|ensemblmetazoa:WBGene00007840(gene)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_872049.2|wormbase:C31C9.6|uniprotkb:Q8I4M6(identity)|wormbase:WBGene00007840(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:huZLaHG/E3MLyCCJa5FNBcjs4RQ6239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:578B7E9696E040FC|rigid:LVXBSrWGR+JV3Xxucp7UztyVU+U false - sufficient binding region:418-475(IPR001452) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBH3 uniprotkb:G5ED33 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536561|imex:IM-18681-391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 35|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:CF86ACAB2BCEE94C|rigid:mbteB+hYtUtrMj8hlT7GDDimzl0 false sufficient binding region:826-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MPT2 uniprotkb:Q65ZJ1 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 intact:EBI-6460396|ensemblmetazoa:C56E6.3b.1 psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:q65zj1_caeel(display_long)|uniprotkb:C56E6.3(orf name)|uniprotkb:toe-2(gene name)|psi-mi:toe-2(display_short)|uniprotkb:CELE_C56E6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536593|imex:IM-18681-393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) ensemblmetazoa:C56E6.3b.1(transcript)|ensemblmetazoa:WBGene00016971(gene)|go:"GO:0016301"(kinase activity)|refseq:NP_001022043.1|wormbase:C56E6.3b|interpro:IPR036388|uniprotkb:Q65ZJ1(identity)|wormbase:WBGene00016971(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 rogid:Bd6MaTCPnGoHXzu2IqsJGGRca7w6239 intact-crc:CC3757220EE901D2|rigid:OTGF5QV53eUvP2r8ZtuluotBszQ false sufficient binding region:418-475(IPR001452) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E3W743 uniprotkb:Q8MPT2 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536608|imex:IM-18681-394 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 93|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:D1ACF2FDD580832A|rigid:5oGfN04emZiKKP/hTzHs5gwQBJI false - sufficient binding region:418-475(IPR001452) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MPT2 uniprotkb:Q22624 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 intact:EBI-6536638|ensemblmetazoa:T21B10.3.1 psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:q22624_caeel(display_long)|uniprotkb:CELE_T21B10.3(orf name)|uniprotkb:T21B10.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536640|imex:IM-18681-396 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) ensemblmetazoa:T21B10.3.1(transcript)|ensemblmetazoa:WBGene00011885(gene)|wormbase:T21B10.3|uniprotkb:Q22624(identity)|wormbase:WBGene00011885(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/01/16 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 rogid:2lrVO10+thJ4w/DSqVqGAM4vNgs6239 intact-crc:B96379DBF544D7DA|rigid:Z6FNpxI3dqkuTghu17UQr4Na6Cs false sufficient binding region:418-475(IPR001452) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20177 uniprotkb:Q8MPT2 intact:EBI-325747|ensemblmetazoa:F38E9.1.1 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:q20177_caeel(display_long)|uniprotkb:F38E9.1(orf name)|uniprotkb:CELE_F38E9.1(orf name) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536623|imex:IM-18681-395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_510673.1|wormbase:F38E9.1|ensemblmetazoa:F38E9.1.1(transcript)|ensemblmetazoa:WBGene00018184(gene)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008081"(phosphoric diester hydrolase activity)|interpro:IPR017946|interpro:IPR042158|dip:DIP-25899N|uniprotkb:Q20177(identity)|wormbase:WBGene00018184(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:0365vrSc61A665R4aWQd0t/XHNA6239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:0EB610C1FD9E6117|rigid:f8JuZAnL0kKbgasVpZNz/3qBMFM false - sufficient binding region:418-475 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEM0 uniprotkb:Q8MPT2 intact:EBI-315855|ensemblmetazoa:Y45G5AM.1a.1|ensemblmetazoa:Y45G5AM.1a.2|uniprotkb:A0A168HAV7|uniprotkb:Q86PI7 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:nh114_caeel(display_long)|uniprotkb:Y45G5AM.1(orf name)|uniprotkb:nhr-114(gene name)|psi-mi:nhr-114(display_short) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536655|imex:IM-18681-397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9GUI3(uniprot-removed-ac)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|refseq:NP_001024242.1|refseq:NP_001317845.1|wormbase:Y45G5AM.1a|ensemblmetazoa:WBGene00003704(gene)|ensemblmetazoa:Y45G5AM.1a.1(transcript)|ensemblmetazoa:Y45G5AM.1a.2(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0048856"(anatomical structure development)|interpro:IPR035500|wormbase:Y45G5AM.1d|uniprotkb:G5EEM0(identity)|wormbase:WBGene00003704(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:r3xk9wxqtrEVL4eq4F4FzaJPtto6239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:F6D64DB93549C8BF|rigid:LGujuHT0W8WfjKC6K1xj8SO584E false - sufficient binding region:418-475(IPR001452) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEN3 uniprotkb:B1V8A0 intact:EBI-6390483|ensemblmetazoa:C02F4.1.1|ensemblmetazoa:C02F4.1.2 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:g5een3_caeel(display_long)|uniprotkb:C02F4.1(orf name)|uniprotkb:ced-5(gene name)|psi-mi:ced-5(display_short)|uniprotkb:CELE_C02F4.1(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536687|imex:IM-18681-399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501938.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR001452(Src homology-3)|wormbase:C02F4.1|ensemblmetazoa:C02F4.1.1(transcript)|ensemblmetazoa:C02F4.1.2(transcript)|ensemblmetazoa:WBGene00000419(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|reactome:R-CEL-8980692|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-8849471|interpro:IPR032376|interpro:IPR027357|interpro:IPR035892|interpro:IPR026791|interpro:IPR027007|reactome:R-CEL-6798695|reactome:R-CEL-418885|reactome:R-CEL-983231|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|uniprotkb:G5EEN3(identity)|wormbase:WBGene00000419(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:VnDRU/8V7erZT8Bd92lWDszhwGY6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:0AE04E4931484EE5|rigid:311LwC9qDaGG02Db3CZswNW9to4 false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:P91001 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-313007|ensemblmetazoa:B0547.1.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536672|imex:IM-18681-398 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394|uniprotkb:P91001(identity)|wormbase:WBGene00000817(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 intact-crc:6460423BF2FAFF5A|rigid:hUO1M74fRXp7ev3tckeRgcB3egE false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:B1V8A0 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536702|imex:IM-18681-400 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:973302280B9B187E|rigid:uZrEBbhLfl+6qSH3vOA4F0Wa9l0 false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:A0A1C3NSL9 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-327553|ensemblmetazoa:C25A11.4k.1|intact:EBI-11468732|uniprotkb:A0A1C3NSK1|uniprotkb:A0A1C3NSK9|uniprotkb:A0A1C3NSL1|uniprotkb:A0A1C3NSL6|uniprotkb:A0A1C3NSM8|uniprotkb:A0A1C3NSP2|uniprotkb:A0A1C3NSQ2|uniprotkb:G4RTG4|uniprotkb:H2KYC4|uniprotkb:H2KYC6 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:ajm1_caeel(display_long)|uniprotkb:ajm-1(gene name)|psi-mi:ajm-1(display_short)|uniprotkb:CELE_C25A11.4(orf name)|uniprotkb:C25A11.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536717|imex:IM-18681-401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) uniprotkb:Q18138(uniprot-removed-ac)|interpro:IPR038825|wormbase:C25A11.4e|interpro:IPR002893(Zinc finger, MYND-type)|ensemblmetazoa:C25A11.4k.1(transcript)|ensemblmetazoa:WBGene00000100(gene)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044292"(dendrite terminus)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046872"(metal ion binding)|refseq:NP_001317735.1|refseq:NP_001317736.1|refseq:NP_001317888.1|refseq:NP_001317890.1|refseq:NP_001317891.1|refseq:NP_001317897.1|refseq:NP_001317898.1|refseq:NP_001317899.1|refseq:NP_509536.1|refseq:NP_001317887.1|refseq:NP_001317889.1|wormbase:C25A11.4a|wormbase:C25A11.4d|wormbase:C25A11.4f|wormbase:C25A11.4g|wormbase:C25A11.4h|wormbase:C25A11.4i|wormbase:C25A11.4j|wormbase:C25A11.4k|wormbase:C25A11.4l|wormbase:C25A11.4m|uniprotkb:G4RTG4(identity)|wormbase:WBGene00000100(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/26 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:r7BJygBJ3u4aJy/4+mWnsMDUgLo6239 intact-crc:AD9B8C529F596596|rigid:noiCdfNs3ooxNwz1IRVvugLRbcs false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:Q9XZI6 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-311866|uniprotkb:Q95Q72|uniprotkb:Q95Q73|uniprotkb:Q95Q74|uniprotkb:Q95Q75|uniprotkb:Q9UA04|uniprotkb:Q9UA05|uniprotkb:Q9XZI7|uniprotkb:Q9XZI8|uniprotkb:Q9XZI9|ensemblmetazoa:C32E8.10a.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:pical_caeel(display_long)|uniprotkb:C32E8.10(orf name)|uniprotkb:unc-11(gene name)|psi-mi:unc-11(display_short)|uniprotkb:AP180-like adaptor protein(gene name synonym)|uniprotkb:Uncoordinated protein 11(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536732|imex:IM-18681-402 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) ensemblmetazoa:C32E8.10a.1(transcript)|ensemblmetazoa:WBGene00006751(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0040011"(locomotion)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:1902683"(regulation of receptor localization to synapse)|go:"GO:1903539"(protein localization to postsynaptic membrane)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|refseq:NP_001021014.1|refseq:NP_001021015.1|refseq:NP_001021016.1|refseq:NP_491227.1|refseq:NP_491228.1|refseq:NP_491229.1|refseq:NP_491230.1|wormbase:C32E8.10a|wormbase:C32E8.10b|wormbase:C32E8.10c|wormbase:C32E8.10d|wormbase:C32E8.10e|wormbase:C32E8.10f|wormbase:C32E8.10h|reactome:R-CEL-432722|reactome:R-CEL-8856825|reactome:R-CEL-8856828|dip:DIP-25315N|uniprotkb:Q9XZI6(identity)|wormbase:WBGene00006751(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:4JQIZTgKSv8kTdP9aYTzoTQp6L06239 intact-crc:6156A601198FCD0B|rigid:jo7SMMLSGzyH4dzLzAb4ULGbtOw false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18529 uniprotkb:B1V8A0 intact:EBI-314884|ensemblmetazoa:C39D10.7.2|ensemblmetazoa:C39D10.7.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:q18529_caeel(display_long)|uniprotkb:C39D10.7(orf name)|uniprotkb:CELE_C39D10.7(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536747|imex:IM-18681-403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509334.3|wormbase:C39D10.7|ensemblmetazoa:C39D10.7.2(transcript)|ensemblmetazoa:WBGene00016534(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008061"(chitin binding)|interpro:IPR002557(Chitin binding protein, peritrophin-A)|interpro:IPR036508|ensemblmetazoa:C39D10.7.1(transcript)|dip:DIP-27006N|uniprotkb:Q18529(identity)|wormbase:WBGene00016534(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:gnU6jSkV05zYFXSGRFYUIcPLW5Q6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:5EC7B0909B5B772F|rigid:41gGTtH3JbGAqiE+HNRK5M7KFX0 false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:W6RRU8 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-9510706|ensemblmetazoa:C49H3.5c.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:w6rru8_caeel(display_long)|uniprotkb:C49H3.5(orf name)|uniprotkb:ntl-4(gene name)|psi-mi:ntl-4(display_short)|uniprotkb:CELE_C49H3.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536779|imex:IM-18681-405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|refseq:NP_001294150.1|interpro:IPR034261|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|wormbase:C49H3.5c|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|ensemblmetazoa:C49H3.5c.1(transcript)|ensemblmetazoa:WBGene00003827(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0046872"(metal ion binding)|uniprotkb:Q8T3E7(identity)|wormbase:WBGene00003827(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:BLiHVWKDtmt8qFNWbfIPaJPOSwA6239 intact-crc:B2DD9B65B469A751|rigid:aPQm1yd1dxCJ4NZhOZb4PD+2AHc false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:Q18605 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-331810|ensemblmetazoa:C44B9.4.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:q18605_caeel(display_long)|uniprotkb:athp-1(gene name)|psi-mi:athp-1(display_short)|uniprotkb:CELE_C44B9.4(orf name)|uniprotkb:C44B9.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536762|imex:IM-18681-404 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) refseq:NP_499397.2|wormbase:C44B9.4|dip:DIP-27259N|ensemblmetazoa:C44B9.4.1(transcript)|ensemblmetazoa:WBGene00008081(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR042163|uniprotkb:Q18605(identity)|wormbase:WBGene00008081(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 25|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:H5ZuRoDCv1AIMpTM9EehO/NyVd86239 intact-crc:940B4775F6601E96|rigid:BIra2AvjCHhwcD44CaNNNlpJ3Z0 false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:G5ED57 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-327853|ensemblmetazoa:F22E12.1.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:g5ed57_caeel(display_long)|uniprotkb:F22E12.1(orf name)|uniprotkb:CELE_F22E12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536811|imex:IM-18681-407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) uniprotkb:O45916(uniprot-removed-ac)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR020901|refseq:NP_505684.2|wormbase:F22E12.1|ensemblmetazoa:F22E12.1.1(transcript)|ensemblmetazoa:WBGene00009058(gene)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036880|uniprotkb:G5ED57(identity)|wormbase:WBGene00009058(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 14|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:+Rdyx7pnykvpAExFI2L56AHfbIc6239 intact-crc:0EB6EAC3BC52E3D1|rigid:Hrx/hch/UGO/sOeGQq6l/zrvDzY false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A9D4E4 uniprotkb:B1V8A0 intact:EBI-6536798|ensemblmetazoa:F13H6.1b.1|ensemblmetazoa:F13H6.1b.2 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:a9d4e4_caeel(display_long)|uniprotkb:bcl-11(gene name)|psi-mi:bcl-11(display_short)|uniprotkb:CELE_F13H6.1(orf name)|uniprotkb:F13H6.1(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536794|imex:IM-18681-406 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F13H6.1b.1(transcript)|ensemblmetazoa:F13H6.1b.2(transcript)|ensemblmetazoa:WBGene00017430(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001122913.1|wormbase:F13H6.1b|interpro:IPR036236|uniprotkb:A9D4E4(identity)|wormbase:WBGene00017430(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:JvzwXvK36+TbPNFYnrUn/O65V9U6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:0D908F44DD9F3064|rigid:7JzutmViMXzg/yD5eRKChYmf2Kw false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:Q8I7N1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-6536830|ensemblmetazoa:F23H11.4b.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:q8i7n1_caeel(display_long)|uniprotkb:CELE_F23H11.4(orf name)|uniprotkb:F23H11.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536826|imex:IM-18681-408 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) ensemblmetazoa:F23H11.4b.1(transcript)|ensemblmetazoa:WBGene00017760(gene)|refseq:NP_871688.1|wormbase:F23H11.4b|uniprotkb:Q8I7N1(identity)|wormbase:WBGene00017760(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:KGpecISk4snodX96bb3rQom2kEA6239 intact-crc:39F446C26919AC77|rigid:26Ko0fIR5rnz/knhYYWSgAhP5AQ false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E3W743 uniprotkb:B1V8A0 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536843|imex:IM-18681-409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:5B0E6EF14FDDE4DC|rigid:1Cf5dmpfzo/BPZceLzZb8+tElyY false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20330 uniprotkb:B1V8A0 intact:EBI-322042|ensemblmetazoa:F42C5.10.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:q20330_caeel(display_long)|uniprotkb:ifo-1(gene name)|psi-mi:ifo-1(display_short)|uniprotkb:ttm-4(gene name synonym)|uniprotkb:CELE_F42C5.10(orf name)|uniprotkb:F42C5.10(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536875|imex:IM-18681-411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501170.1|wormbase:F42C5.10|ensemblmetazoa:F42C5.10.1(transcript)|ensemblmetazoa:WBGene00018350(gene)|dip:DIP-27375N|uniprotkb:Q20330(identity)|wormbase:WBGene00018350(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:G/TdIwuOTGQMqaW/I1aJ4GvrtlU6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:5BBF75381140307C|rigid:XYxb+7v/h4CsB/IjFY0o3N/7BJI false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95YA9 uniprotkb:B1V8A0 intact:EBI-6536858|ensemblmetazoa:F41G4.2a.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:q95ya9_caeel(display_long)|uniprotkb:F41G4.2(orf name)|uniprotkb:cas-1(gene name)|psi-mi:cas-1(display_short)|uniprotkb:CELE_F41G4.2(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536860|imex:IM-18681-410 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028417|reactome:R-CEL-6798695|ensemblmetazoa:F41G4.2a.1(transcript)|ensemblmetazoa:WBGene00000294(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR017901|wormbase:F41G4.2a|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR036222|interpro:IPR036223|interpro:IPR028419|refseq:NP_510714.1|uniprotkb:Q95YA9(identity)|wormbase:WBGene00000294(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:Wtu62Erja5FAbcy4JVr/DUWQf0w6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:308F1209A26C767D|rigid:rcpiaoXTxMIEg2ZuIKZUZum0aFQ false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:O44743 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-6536890|ensemblmetazoa:F57B10.1.1|ensemblmetazoa:F57B10.1.2 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:le607_caeel(display_long)|uniprotkb:let-607(gene name)|psi-mi:let-607(display_short)|uniprotkb:Lethal 607 protein(gene name synonym)|uniprotkb:F57B10.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536892|imex:IM-18681-412 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) ensemblmetazoa:F57B10.1.1(transcript)|ensemblmetazoa:F57B10.1.2(transcript)|ensemblmetazoa:WBGene00002783(gene)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008361"(regulation of cell size)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0090038"(negative regulation of protein kinase C signaling)|go:"GO:1903354"(regulation of distal tip cell migration)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|refseq:NP_491897.2|wormbase:F57B10.1|reactome:R-CEL-8874211|uniprotkb:O44743(identity)|wormbase:WBGene00002783(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:X2AJG1A5B8znvxnq2MEf4OqBQmM6239 intact-crc:306853D2A9E7FB15|rigid:FGJLTZcKsa843Mexx+AxGZiroOk false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q94246 uniprotkb:B1V8A0 intact:EBI-6461124|ensemblmetazoa:F57F4.3.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:q94246_caeel(display_long)|uniprotkb:F57F4.3(orf name)|uniprotkb:gfi-1(gene name)|psi-mi:gfi-1(display_short)|uniprotkb:CELE_F57F4.3(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536907|imex:IM-18681-413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F57F4.3.1(transcript)|ensemblmetazoa:WBGene00001581(gene)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0045121"(membrane raft)|interpro:IPR002603(Protein of unknown function ET)|refseq:NP_504626.1|wormbase:F57F4.3|uniprotkb:Q94246(identity)|wormbase:WBGene00001581(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 20|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:Dap7huO6cWZv2f48TbdB1CMIcdg6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:C8B3908E3D40EC11|rigid:Wd+rfr6k7e6WGVxZ9qM75WsbZA0 false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01900 uniprotkb:B1V8A0 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536922|imex:IM-18681-414 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:DBEEDEF4D22F5BF1|rigid:1l3j1wCiEoim3/aPkJbfGz7AXBw false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:O17214 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-319290|ensemblmetazoa:H14A12.2a.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:fumh_caeel(display_long)|uniprotkb:H14A12.2(orf name)|uniprotkb:fum-1(gene name)|psi-mi:fum-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536937|imex:IM-18681-415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) ensemblmetazoa:H14A12.2a.1(transcript)|ensemblmetazoa:WBGene00001503(gene)|go:"GO:0004333"(fumarate hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|interpro:IPR020557|interpro:IPR022761|interpro:IPR024083|refseq:NP_498642.1|wormbase:H14A12.2a|reactome:R-CEL-71403|dip:DIP-25418N|uniprotkb:O17214(identity)|wormbase:WBGene00001503(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:fFt+5dBFVE2bfEfITZ0ZA6MjVI46239 intact-crc:B69A794979472FFC|rigid:KhCaj9uLoVj/MWhJcfG9L7UdNzE false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL2 uniprotkb:B1V8A0 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536952|imex:IM-18681-416 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:512EEC8A8FA28EC8|rigid:kHSIUHuNrKNP2bD7U6/cxAYOgIM false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:Q09994 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-6536971|ensemblmetazoa:K10B2.5.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:ani2_caeel(display_long)|uniprotkb:ani-2(gene name)|psi-mi:ani-2(display_short)|uniprotkb:K10B2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536967|imex:IM-18681-417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) ensemblmetazoa:K10B2.5.1(transcript)|ensemblmetazoa:WBGene00019608(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0006949"(syncytium formation)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030728"(ovulation)|go:"GO:0031106"(septin ring organization)|go:"GO:0032504"(multicellular organism reproduction)|go:"GO:0048477"(oogenesis)|reactome:R-CEL-8980692|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012966(Protein of unknown function DUF1709, fungi)|refseq:NP_495282.1|wormbase:K10B2.5|interpro:IPR037840|uniprotkb:Q09994(identity)|wormbase:WBGene00019608(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:m1XIlRhuuVzO0AK6jMX3ZhYVS906239 intact-crc:1697267B6B5B72B8|rigid:2A23ICGa2AYazbvKf4Nv0G5EQY0 false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:B2D6P5 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-2919829|ensemblmetazoa:M04G12.1c.1|ensemblmetazoa:M04G12.1c.2 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:b2d6p5_caeel(display_long)|uniprotkb:tag-260(gene name)|psi-mi:tag-260(display_short)|uniprotkb:ifbp-1(gene name synonym)|uniprotkb:CELE_M04G12.1(orf name)|uniprotkb:M04G12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536999|imex:IM-18681-419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) ensemblmetazoa:M04G12.1c.1(transcript)|ensemblmetazoa:M04G12.1c.2(transcript)|ensemblmetazoa:WBGene00010867(gene)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR022750|refseq:NP_001122980.1|wormbase:M04G12.1c|interpro:IPR044882|uniprotkb:B2D6P5(identity)|wormbase:WBGene00010867(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:MBUav8DZj3WeqUqpxjtet5cli/w6239 intact-crc:D1F2B0B2AB081A49|rigid:Mq8aUDuOwhLKk3EMAX+x/oge0qs false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:P10986 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-321916|uniprotkb:Q7YSY2|ensemblmetazoa:M03F4.2a.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:act4_caeel(display_long)|uniprotkb:act-4(gene name)|psi-mi:act-4(display_short)|uniprotkb:M03F4.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6536984|imex:IM-18681-418 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) refseq:NP_508841.1|wormbase:M03F4.2a|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|ensemblmetazoa:M03F4.2a.1(transcript)|ensemblmetazoa:WBGene00000066(gene)|go:"GO:0000281"(mitotic cytokinesis)|dip:DIP-27204N|uniprotkb:P10986(identity)|wormbase:WBGene00000066(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:zehthX6Qo/gSO5k1j5Epcffr8Sc6239 intact-crc:FF13084E291A08BC|rigid:WsUxhLw6WjcCIx48U8t+UVyN1bk false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34552 uniprotkb:B1V8A0 intact:EBI-322767|uniprotkb:Q7YXC7|uniprotkb:Q8I114|uniprotkb:Q8I115|uniprotkb:Q94159|ensemblmetazoa:R10E12.1b.1|ensemblmetazoa:R10E12.1b.2 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:alxa_caeel(display_long)|uniprotkb:alx-1(gene name)|psi-mi:alx-1(display_short)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 58"(gene name synonym)|uniprotkb:Protein YNK1(gene name synonym)|uniprotkb:pqn-58(gene name synonym)|uniprotkb:R10E12.1(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537029|imex:IM-18681-421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022713.1|refseq:NP_001022714.1|refseq:NP_001022715.1|refseq:NP_499213.1|wormbase:R10E12.1a|wormbase:R10E12.1b|wormbase:R10E12.1c|wormbase:R10E12.1d|interpro:IPR004328(BRO1)|interpro:IPR025304|ensemblmetazoa:R10E12.1b.1(transcript)|ensemblmetazoa:R10E12.1b.2(transcript)|ensemblmetazoa:WBGene00007010(gene)|go:"GO:0005112"(Notch binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0007032"(endosome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043226"(organelle)|go:"GO:0055037"(recycling endosome)|interpro:IPR038499|uniprotkb:P34552(identity)|wormbase:WBGene00007010(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 24|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:xedXAHU8Ms6VcKj1w9YZDHURHHg6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:0695A092F7B7F244|rigid:jyuf3jF67C26qiX5Sjm4xddCGkk false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:Q7JP60 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-6534568|ensemblmetazoa:R08E3.3b.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:q7jp60_caeel(display_long)|uniprotkb:CELE_R08E3.3(orf name)|uniprotkb:R08E3.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537014|imex:IM-18681-420 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) ensemblmetazoa:R08E3.3b.1(transcript)|ensemblmetazoa:WBGene00019959(gene)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|refseq:NP_001024849.1|wormbase:R08E3.3b|reactome:R-CEL-8951664|uniprotkb:Q7JP60(identity)|wormbase:WBGene00019959(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:HfBZf7yrrXcSNeQmWUPq7B2XOCk6239 intact-crc:51A04A8BFA9AF7F8|rigid:3MrLvbQ280bg2LewA3rjnuP5ODM false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:O61708 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-315255|ensemblmetazoa:R119.4.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:o61708_caeel(display_long)|uniprotkb:pqn-59(gene name)|psi-mi:pqn-59(display_short)|uniprotkb:CELE_R119.4(orf name)|uniprotkb:R119.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537044|imex:IM-18681-422 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) refseq:NP_490727.1|wormbase:R119.4|ensemblmetazoa:R119.4.1(transcript)|ensemblmetazoa:WBGene00004143(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR009060(UBA-like)|dip:DIP-25020N|uniprotkb:O61708(identity)|wormbase:WBGene00004143(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:K83JJthOIli1KrkmuKJbMtYpX7I6239 intact-crc:21DC92384E6549C5|rigid:Y135zVlsF6OXPPIAILmIJC3iPTI false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:Q09345 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-2006279|ensemblmetazoa:R144.2a.1|ensemblmetazoa:R144.2a.2 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:pcf11_caeel(display_long)|uniprotkb:R144.2(orf name)|uniprotkb:pcf-11(gene name)|psi-mi:pcf-11(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537059|imex:IM-18681-423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) refseq:NP_498068.1|wormbase:R144.2a|interpro:IPR008942(ENTH/VHS)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|reactome:R-CEL-6807505|reactome:R-CEL-73856|ensemblmetazoa:R144.2a.1(transcript)|ensemblmetazoa:R144.2a.2(transcript)|ensemblmetazoa:WBGene00020092(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|uniprotkb:Q09345(identity)|wormbase:WBGene00020092(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:XTyRR+k9dN5uoxwUXnAuM34SSUA6239 intact-crc:E9A323CFDC522596|rigid:ZnulToebYmGszWR7A3sksMt0hAU false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q94046 uniprotkb:B1V8A0 intact:EBI-6537078|ensemblmetazoa:T13F2.3a.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:q94046_caeel(display_long)|uniprotkb:T13F2.3(orf name)|uniprotkb:pis-1(gene name)|psi-mi:pis-1(display_short)|uniprotkb:CELE_T13F2.3(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537074|imex:IM-18681-424 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T13F2.3a.1(transcript)|ensemblmetazoa:WBGene00004031(gene)|interpro:IPR001357(BRCT)|refseq:NP_501749.1|wormbase:T13F2.3a|interpro:IPR036420|uniprotkb:Q94046(identity)|wormbase:WBGene00004031(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:9SiUQHiuHrzrUIsXFWiO8DuOeIQ6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:2E98C02D54139F88|rigid:ektm3EaxGTjFvHLEDTJurB3LPew false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B9WRT9 uniprotkb:B1V8A0 intact:EBI-6537091|ensemblmetazoa:W01F3.3b.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:b9wrt9_caeel(display_long)|uniprotkb:W01F3.3(orf name)|uniprotkb:mlt-11(gene name)|psi-mi:mlt-11(display_short)|uniprotkb:CELE_W01F3.3(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537093|imex:IM-18681-425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:W01F3.3b.1(transcript)|ensemblmetazoa:WBGene00012186(gene)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR006150(Cysteine-rich repeat)|interpro:IPR020901|refseq:NP_001256938.1|wormbase:W01F3.3b|interpro:IPR028150|interpro:IPR036857|interpro:IPR036880|uniprotkb:B9WRT9(identity)|wormbase:WBGene00012186(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:CgK0Ngmh9vQ13OdY4piBQ52UlWI6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:E196E7F1B5A0E1EE|rigid:HMv7QUVWL/zd5RFlhG/FEVdi4CI false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17350 uniprotkb:B1V8A0 intact:EBI-6533065 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:q17350_caeel(display_long) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537123|imex:IM-18681-427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|uniprotkb:Q17350(identity)|wormbase:WBGene00003902(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:WMhX/u/7thd5HOTeDmBBv136pPY6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:7FF913E678AC5181|rigid:AZOfuXVpCd9QJBYkWv6o72a2DSM false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:Q9UA61 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-332088|ensemblmetazoa:W04B5.3a.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:q9ua61_caeel(display_long)|uniprotkb:W04B5.3(orf name)|uniprotkb:CELE_W04B5.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537108|imex:IM-18681-426 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) refseq:NP_741097.1|wormbase:W04B5.3a|dip:DIP-24301N|ensemblmetazoa:W04B5.3a.1(transcript)|ensemblmetazoa:WBGene00021020(gene)|go:"GO:0030246"(carbohydrate binding)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|uniprotkb:Q9UA61(identity)|wormbase:WBGene00021020(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:G/NFALVsz5wdyKCfC7PtqUoOL5g6239 intact-crc:501B32B40F595955|rigid:34ZlOiIvLZ5WJcjDEnq35nTmps4 false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:G5EBN5 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-6537138|ensemblmetazoa:Y53H1C.2a.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:g5ebn5_caeel(display_long)|uniprotkb:Y53H1C.2(orf name)|uniprotkb:ego-2(gene name)|psi-mi:ego-2(display_short)|uniprotkb:CELE_Y53H1C.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537140|imex:IM-18681-428 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) ensemblmetazoa:Y53H1C.2a.1(transcript)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|ensemblmetazoa:WBGene00001215(gene)|interpro:IPR004328(BRO1)|interpro:IPR025304|refseq:NP_001076622.2|wormbase:Y53H1C.2a|interpro:IPR038499|uniprotkb:G5EBN5(identity)|wormbase:WBGene00001215(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:6wX3psHuVdMf/E13BN1BLJR7Iag6239 intact-crc:19816ABFB01CC1EB|rigid:oxr+EjwwOHnFF/WHR9HSTnOIYYA false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:P19826 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-322152|ensemblmetazoa:ZC477.9d.1|uniprotkb:Q9BI32|uniprotkb:Q8MPS2|uniprotkb:Q9BI31|uniprotkb:V6CJ36|uniprotkb:V6CK82|uniprotkb:V6CLG2|uniprotkb:V6CLK1|uniprotkb:V6CLL2 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:vinc_caeel(display_long)|uniprotkb:deb-1(gene name)|psi-mi:deb-1(display_short)|uniprotkb:ZC477.9(orf name)|uniprotkb:P107B(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537155|imex:IM-18681-429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) ensemblmetazoa:WBGene00000942(gene)|ensemblmetazoa:ZC477.9d.1(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0060279"(positive regulation of ovulation)|go:"GO:0097433"(dense body)|reactome:R-CEL-445355|reactome:R-CEL-5674135|refseq:NP_501104.2|wormbase:ZC477.9a|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR000633(Vinculin, conserved site)|refseq:NP_001293743.1|refseq:NP_001293744.1|refseq:NP_001293745.1|refseq:NP_001293746.1|refseq:NP_001293747.1|refseq:NP_501105.2|refseq:NP_741437.1|reactome:R-CEL-114608|reactome:R-CEL-6798695|interpro:IPR017997|interpro:IPR036723|wormbase:ZC477.9b|wormbase:ZC477.9c|wormbase:ZC477.9d|wormbase:ZC477.9e|wormbase:ZC477.9f|wormbase:ZC477.9g|wormbase:ZC477.9h|uniprotkb:P19826(identity)|wormbase:WBGene00000942(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:AdSmuwqJNzwZuJwyZ30NpUvUdtk6239 intact-crc:212BCE2223DDCCC3|rigid:FNF+IVP3SkkDd0ofSGFtdIqo5ko false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BIF4 uniprotkb:B1V8A0 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537170|imex:IM-18681-430 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 57|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/09 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:E21D2878019FA267|rigid:mrejwrZBnmUuBtUwp70zD4QQgxA false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23158 uniprotkb:O01661 intact:EBI-314014|ensemblmetazoa:W04D2.1a.1 intact:EBI-6537185|ensemblmetazoa:T28F2.5.1 psi-mi:q23158_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:CELE_W04D2.1(orf name)|uniprotkb:W04D2.1(orf name) psi-mi:o01661_caeel(display_long)|uniprotkb:T28F2.5(orf name)|uniprotkb:ccb-1(gene name)|psi-mi:ccb-1(display_short)|uniprotkb:CELE_T28F2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537187|imex:IM-18681-431 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-114608|reactome:R-CEL-446388|reactome:R-CEL-438066|reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_506127.1|wormbase:W04D2.1a|ensemblmetazoa:W04D2.1a.1(transcript)|ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0097433"(dense body)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|dip:DIP-25407N|uniprotkb:Q23158(identity)|wormbase:WBGene00000228(identity) reactome:R-CEL-112308|ensemblmetazoa:T28F2.5.1(transcript)|ensemblmetazoa:WBGene00000368(gene)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0061199"(striated muscle contraction involved in embryonic body morphogenesis)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|refseq:NP_491193.2|wormbase:T28F2.5|interpro:IPR027417|interpro:IPR036028|reactome:R-CEL-422356|reactome:R-CEL-5576892|reactome:R-CEL-5576893|uniprotkb:O01661(identity)|wormbase:WBGene00000368(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Iy6/ip1Rm3/Yb1HK7rHlSeScT006239 rogid:Khadhwx+FsP2ztUMwxF1vFtY3XI6239 intact-crc:25DC2C53885715F3|rigid:dshw2Gc9W4JYi6yawzggU80QCH0 false - sufficient binding region:51-115 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A0A1C3NSL9 uniprotkb:Q9U2Z5 intact:EBI-327553|ensemblmetazoa:C25A11.4k.1|intact:EBI-11468732|uniprotkb:A0A1C3NSK1|uniprotkb:A0A1C3NSK9|uniprotkb:A0A1C3NSL1|uniprotkb:A0A1C3NSL6|uniprotkb:A0A1C3NSM8|uniprotkb:A0A1C3NSP2|uniprotkb:A0A1C3NSQ2|uniprotkb:G4RTG4|uniprotkb:H2KYC4|uniprotkb:H2KYC6 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:ajm1_caeel(display_long)|uniprotkb:ajm-1(gene name)|psi-mi:ajm-1(display_short)|uniprotkb:CELE_C25A11.4(orf name)|uniprotkb:C25A11.4(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537217|imex:IM-18681-433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q18138(uniprot-removed-ac)|interpro:IPR038825|wormbase:C25A11.4e|interpro:IPR002893(Zinc finger, MYND-type)|ensemblmetazoa:C25A11.4k.1(transcript)|ensemblmetazoa:WBGene00000100(gene)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044292"(dendrite terminus)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046872"(metal ion binding)|refseq:NP_001317735.1|refseq:NP_001317736.1|refseq:NP_001317888.1|refseq:NP_001317890.1|refseq:NP_001317891.1|refseq:NP_001317897.1|refseq:NP_001317898.1|refseq:NP_001317899.1|refseq:NP_509536.1|refseq:NP_001317887.1|refseq:NP_001317889.1|wormbase:C25A11.4a|wormbase:C25A11.4d|wormbase:C25A11.4f|wormbase:C25A11.4g|wormbase:C25A11.4h|wormbase:C25A11.4i|wormbase:C25A11.4j|wormbase:C25A11.4k|wormbase:C25A11.4l|wormbase:C25A11.4m|uniprotkb:G4RTG4(identity)|wormbase:WBGene00000100(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/26 rogid:r7BJygBJ3u4aJy/4+mWnsMDUgLo6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:67754652F53D8B83|rigid:zkka1N2opw+jVGJaGnm29WDFaLQ false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:Q09442 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537202|imex:IM-18681-432 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 21|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 intact-crc:14CB5FDF041D8902|rigid:4QhAAf/yD0+sRAgj3VuNgyNXP7w false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18605 uniprotkb:Q9U2Z5 intact:EBI-331810|ensemblmetazoa:C44B9.4.1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:q18605_caeel(display_long)|uniprotkb:athp-1(gene name)|psi-mi:athp-1(display_short)|uniprotkb:CELE_C44B9.4(orf name)|uniprotkb:C44B9.4(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537247|imex:IM-18681-435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499397.2|wormbase:C44B9.4|dip:DIP-27259N|ensemblmetazoa:C44B9.4.1(transcript)|ensemblmetazoa:WBGene00008081(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR042163|uniprotkb:Q18605(identity)|wormbase:WBGene00008081(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:H5ZuRoDCv1AIMpTM9EehO/NyVd86239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:74539627930F4BBE|rigid:rWOGKOLgrzUqVZC/ybsivxKE/5Q false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B7WN72 uniprotkb:Q9U2Z5 intact:EBI-2914750|ensemblmetazoa:C33B4.3c.1|uniprotkb:Q09493|uniprotkb:Q7JMK1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:shank_caeel(display_long)|uniprotkb:shn-1(gene name)|psi-mi:shn-1(display_short)|uniprotkb:C33B4.3(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537232|imex:IM-18681-434 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C33B4.3c.1(transcript)|ensemblmetazoa:WBGene00006444(gene)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030421"(defecation)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043197"(dendritic spine)|reactome:R-CEL-6794361|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|wormbase:C33B4.3c|wormbase:C33B4.3a|wormbase:C33B4.3b|refseq:NP_001254297.1|interpro:IPR036034|interpro:IPR036770|refseq:NP_001022006.1|refseq:NP_001022007.1|uniprotkb:B7WN72(identity)|wormbase:WBGene00006444(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MxlKCcp7iFWP6a9kDPFIvqKhOlY6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:17A3D4890DB55F64|rigid:xxx+w8x0X5/NFzDwY20XzohoRHA false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O61701 uniprotkb:Q9U2Z5 intact:EBI-6537266 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:o61701_caeel(display_long)|uniprotkb:cyk-1(gene name)|psi-mi:cyk-1(display_short) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537262|imex:IM-18681-436 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003779"(actin binding)|go:"GO:0016043"(cellular component organization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|uniprotkb:O61701(identity)|wormbase:WBGene00000872(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:3tZm/rdSqLAK4eIpP1J9faYAo7w6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:281085FE5A71914F|rigid:RJdhfVhyqnTCvHPCiAbstHQozW4 false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19479 uniprotkb:Q9U2Z5 intact:EBI-6537279|ensemblmetazoa:F15B9.4.1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:q19479_caeel(display_long)|uniprotkb:F15B9.4(orf name)|uniprotkb:inft-2(gene name)|psi-mi:inft-2(display_short)|uniprotkb:CELE_F15B9.4(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537281|imex:IM-18681-437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F15B9.4.1(transcript)|ensemblmetazoa:WBGene00008848(gene)|reactome:R-CEL-5663220|reactome:R-CEL-6785631|reactome:R-CEL-6798695|reactome:R-CEL-8980692|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9035034|interpro:IPR015425(Actin-binding FH2)|refseq:NP_506253.4|wormbase:F15B9.4|interpro:IPR042201|uniprotkb:Q19479(identity)|wormbase:WBGene00008848(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:hrYLHf8DOYOYmFVLXuOULN7MFcQ6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:9E0FBADB056CCB0C|rigid:Pu9KidTopiUpWOlpgWIxnAumuF8 false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3Y407 uniprotkb:Q9U2Z5 intact:EBI-2317687|uniprotkb:G4SJ35|ensemblmetazoa:F46H5.6.1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:q3y407_caeel(display_long)|uniprotkb:grd-7(gene name)|psi-mi:grd-7(display_short)|uniprotkb:CELE_F46H5.6(orf name)|uniprotkb:F46H5.6(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537311|imex:IM-18681-439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007284(Ground-like region)|wormbase:F46H5.6|interpro:IPR003882(Pistil-specific extensin-like protein)|ensemblmetazoa:F46H5.6.1(transcript)|ensemblmetazoa:WBGene00001696(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007154"(cell communication)|uniprotkb:Q3Y407(identity)|wormbase:WBGene00001696(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/01/23 rogid:77+Ww780xL2+LUmBj5htUR6eidA6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:012E9625DCF763A0|rigid:LyPSEQNsq9kNl8FlHpVGyU75caw false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95YA9 uniprotkb:Q9U2Z5 intact:EBI-6536858|ensemblmetazoa:F41G4.2a.1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:q95ya9_caeel(display_long)|uniprotkb:F41G4.2(orf name)|uniprotkb:cas-1(gene name)|psi-mi:cas-1(display_short)|uniprotkb:CELE_F41G4.2(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537296|imex:IM-18681-438 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028417|reactome:R-CEL-6798695|ensemblmetazoa:F41G4.2a.1(transcript)|ensemblmetazoa:WBGene00000294(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR017901|wormbase:F41G4.2a|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR036222|interpro:IPR036223|interpro:IPR028419|refseq:NP_510714.1|uniprotkb:Q95YA9(identity)|wormbase:WBGene00000294(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:Wtu62Erja5FAbcy4JVr/DUWQf0w6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:63309F36173194AF|rigid:unAaOIlP6sq9Zf4yNIVh8WSUyHw false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:G5ECL2 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537341|imex:IM-18681-441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 intact-crc:7567487789E8A083|rigid:HT31tHuSG0CU4st2AF+43zj/2k4 false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:O01900 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537326|imex:IM-18681-440 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 intact-crc:5192C5DA5798A930|rigid:q8PbezXx0TooRXG+BlF69r9dq+g false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:B5WWM0 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-6537371|ensemblmetazoa:Y40B1A.3b.1 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:b5wwm0_caeel(display_long)|uniprotkb:wac-1.1(gene name)|psi-mi:wac-1.1(display_short)|uniprotkb:CELE_Y40B1A.3(orf name)|uniprotkb:Y40B1A.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537373|imex:IM-18681-443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) ensemblmetazoa:WBGene00012734(gene)|ensemblmetazoa:Y40B1A.3b.1(transcript)|refseq:NP_001252144.1|wormbase:Y40B1A.3b|uniprotkb:B5WWM0(identity)|wormbase:WBGene00012734(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:6m5o1xEUC4gONpb0CWM5/ZmCYuY6239 intact-crc:137BDF1DD19AD47A|rigid:U7KAeOVCy1zWM/yFaIA0S3BvfVI false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:Q9U2Z5 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537356|imex:IM-18681-442 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 21|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:DB5076E9BCB589A7|rigid:K4mTgGL91PyV3jRyncyGFCLkDr0 false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EG53 uniprotkb:Q9U2Z5 intact:EBI-6536086|ensemblmetazoa:Y50D4C.1a.1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:g5eg53_caeel(display_long)|uniprotkb:Y50D4C.1(orf name)|uniprotkb:unc-34(gene name)|psi-mi:unc-34(display_short)|uniprotkb:CELE_Y50D4C.1(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537403|imex:IM-18681-445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006770(gene)|ensemblmetazoa:Y50D4C.1a.1(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032433"(filopodium tip)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040017"(positive regulation of locomotion)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_503360.4|wormbase:Y50D4C.1a|reactome:R-CEL-446353|uniprotkb:G5EG53(identity)|wormbase:WBGene00006770(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 27|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:YztDB2tZk9JFqV25NJfYSwPW5Xo6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:E7C901E467FDF3A2|rigid:x6wEeAiTtxKt1NT9DLZi7YE/0sw false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UB01 uniprotkb:Q9U2Z5 intact:EBI-6533589|ensemblmetazoa:Y4C6B.1.1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:q9ub01_caeel(display_long)|uniprotkb:CELE_Y4C6B.1(orf name)|uniprotkb:Y4C6B.1(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537388|imex:IM-18681-444 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021155(gene)|ensemblmetazoa:Y4C6B.1.1(transcript)|refseq:NP_500786.1|wormbase:Y4C6B.1|uniprotkb:Q9UB01(identity)|wormbase:WBGene00021155(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:z00tk6D2d6frL+hGJ2HSZ72CNcs6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:1A525148ABB8AF11|rigid:pi9HUB/9O7SyQ6txusyfYnxUTI0 false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91001 uniprotkb:Q9U2T9 intact:EBI-313007|ensemblmetazoa:B0547.1.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537433|imex:IM-18681-447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394|uniprotkb:P91001(identity)|wormbase:WBGene00000817(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:49AB33EBAC22E9CB|rigid:6+pHD33Wh2ksMdJY9TLinjLEJbE false - sufficient binding region:676-733 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:Q9U2Z5 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537418|imex:IM-18681-446 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 38|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:BD2FE7AF2F5AE145|rigid:jcbrKwkEbYqkmHvggxD3eHco310 false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q19905 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537448|imex:IM-18681-448 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N|uniprotkb:Q19905(identity)|wormbase:WBGene00005022(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 intact-crc:B7255471A5157C8E|rigid:A4iAhJs3tPF8FPKB4O5OQ7gyhdM false sufficient binding region:676-733 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:P91820 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537478|imex:IM-18681-450 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N|uniprotkb:P91820(identity)|wormbase:WBGene00003083(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 34|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 intact-crc:C4049A380039A196|rigid:xdZjxh+ti839T6hz2gcfG0htNZw false sufficient binding region:676-733 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16299 uniprotkb:Q9U2T9 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537463|imex:IM-18681-449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 88|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:F8B9C4165B7A7403|rigid:bcJqmzHKDVV1D0O4nEKf+8kLjjA false - sufficient binding region:676-733 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q9XWN1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-324865|ensemblmetazoa:Y43F8C.6a.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:q9xwn1_caeel(display_long)|uniprotkb:Y43F8C.6(orf name)|uniprotkb:CELE_Y43F8C.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537493|imex:IM-18681-451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_001256880.1|wormbase:Y43F8C.6a|ensemblmetazoa:WBGene00012828(gene)|ensemblmetazoa:Y43F8C.6a.1(transcript)|go:"GO:0016589"(NURF complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR037931|dip:DIP-27198N|uniprotkb:Q9XWN1(identity)|wormbase:WBGene00012828(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:BnRBxnWaRRWRCAx+LGlNwRaOcOU6239 intact-crc:4E753E76DA85EA2F|rigid:s2F7G31SQYfl3vw5JCB39Hco6K0 false sufficient binding region:676-733 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:G5ECL2 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537508|imex:IM-18681-452 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 intact-crc:679BD52EA471DAAD|rigid:JEN4TFfXBtCrP4UkXvaAZnvCJ6E false sufficient binding region:795-850 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O18181 uniprotkb:Q9U2T9 intact:EBI-314025|ensemblmetazoa:W09D10.1.1|ensemblmetazoa:W09D10.1.2|ensemblmetazoa:W09D10.1.3 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:o18181_caeel(display_long)|uniprotkb:W09D10.1(orf name)|uniprotkb:CELE_W09D10.1(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537523|imex:IM-18681-453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499364.1|wormbase:W09D10.1|ensemblmetazoa:W09D10.1.1(transcript)|ensemblmetazoa:W09D10.1.2(transcript)|ensemblmetazoa:W09D10.1.3(transcript)|ensemblmetazoa:WBGene00012359(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|interpro:IPR044732|dip:DIP-25493N|uniprotkb:O18181(identity)|wormbase:WBGene00012359(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:cHeZ4L5WfJqv9iJlDcYYy+cOz3k6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:545BB1226723DD07|rigid:JQEPSmOyoZp68iaFO7TO9vRfT4g false - sufficient binding region:897-951 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:D0IMZ5 uniprotkb:Q9U2T9 intact:EBI-6534036|ensemblmetazoa:Y66H1B.2a.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:d0imz5_caeel(display_long)|uniprotkb:Y66H1B.2(orf name)|uniprotkb:fln-1(gene name)|psi-mi:fln-1(display_short)|uniprotkb:CELE_Y66H1B.2(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537538|imex:IM-18681-454 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00022048(gene)|ensemblmetazoa:Y66H1B.2a.1(transcript)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0061038"(uterus morphogenesis)|interpro:IPR044801|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|refseq:NP_001023550.2|wormbase:Y66H1B.2a|interpro:IPR036872|uniprotkb:D0IMZ5(identity)|wormbase:WBGene00022048(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:9hCmcqWxWSY2QYeg05bDz4qoY/U6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:DFBE1B020C043290|rigid:WeRO7icHY/0MmUiol+W+Eayt89k false - sufficient binding region:897-951 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XTY6 uniprotkb:Q9U2T9 intact:EBI-495781|uniprotkb:Q9BKB5|uniprotkb:Q9XTY4|ensemblmetazoa:T03D8.1a.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:numb1_caeel(display_long)|uniprotkb:Protein kinase C adapter 1(gene name synonym)|uniprotkb:CKA1(gene name synonym)|uniprotkb:num-1(gene name)|psi-mi:num-1(display_short)|uniprotkb:cka-1(gene name synonym)|uniprotkb:T03D8.1(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537553|imex:IM-18681-455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024097.1|refseq:NP_001024098.1|refseq:NP_508021.1|wormbase:T03D8.1a|wormbase:T03D8.1b|wormbase:T03D8.1c|interpro:IPR016698(Numb/numb-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|reactome:R-CEL-437239|reactome:R-CEL-5610780|reactome:R-CEL-5632684|ensemblmetazoa:T03D8.1a.1(transcript)|ensemblmetazoa:WBGene00003830(gene)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0051117"(ATPase binding)|uniprotkb:Q9XTY6(identity)|wormbase:WBGene00003830(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 90|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qO+DFvMBt2DE+ZS7l8axk5DMOFQ6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:3B4F03FE6B380547|rigid:n/cdSAKvhrrEcwawI0/J07caUBM false - sufficient binding region:974-1033 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-324875 uniprotkb:Q9U2T9 - intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:g5edc2_caeel(display_short)|psi-mi:EBI-324875(display_long)|uniprotkb:Y57A10A.1(orf name)|uniprotkb:CELE_Y57A10A.1(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537568|imex:IM-18681-456 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:G5EDC2(uniprot-removed-ac)|uniprotkb:G5EDC2(identity)|wormbase:WBGene00013246(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:WT6UhJFiUAk07DOFIH7BHJkVnT06239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:8B23F26A8AC3F731|rigid:5gOveMA5mhwK2HbWjSafgA99Gjg false - sufficient binding region:974-1033 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:O18246 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-317099|ensemblmetazoa:Y57G11C.22a.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:o18246_caeel(display_long)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:CELE_Y57G11C.22(orf name)|uniprotkb:Y57G11C.22(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537583|imex:IM-18681-457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_001041046.1|wormbase:Y57G11C.22a|ensemblmetazoa:WBGene00013317(gene)|ensemblmetazoa:Y57G11C.22a.1(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-27078N|uniprotkb:O18246(identity)|wormbase:WBGene00013317(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 33|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:EwNg/0sCGH1I5xMzixpfij4S4Gk6239 intact-crc:46E6E63F2F1C5307|rigid:Ga9EAFdWo5QRdrPr10riR/P8n4w false sufficient binding region:974-1033 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91001 uniprotkb:Q95XA9 intact:EBI-313007|ensemblmetazoa:B0547.1.1 intact:EBI-6537613|ensemblmetazoa:Y20F4.3a.1|uniprotkb:G4SRM7 psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:q95xa9_caeel(display_long)|uniprotkb:Y20F4.3(orf name)|uniprotkb:gap-3(gene name)|psi-mi:gap-3(display_short)|uniprotkb:CELE_Y20F4.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537615|imex:IM-18681-459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394|uniprotkb:P91001(identity)|wormbase:WBGene00000817(identity) ensemblmetazoa:WBGene00021238(gene)|ensemblmetazoa:Y20F4.3a.1(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0043409"(negative regulation of MAPK cascade)|wormbase:Y20F4.3a|reactome:R-CEL-186763|reactome:R-CEL-8849471|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|refseq:NP_490916.5|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95XA9(identity)|wormbase:WBGene00021238(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 rogid:W7Klw/TiaXQdDxym/p8FIth/Gn46239 intact-crc:74EB270970053CCD|rigid:m0YVBZM4lBJHHxJld6QsrTtoLgk false - sufficient binding region:211-268 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4A9 uniprotkb:Q9U2T9 intact:EBI-324656|ensemblmetazoa:Y77E11A.2.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:q9n4a9_caeel(display_long)|uniprotkb:nadk-1(gene name)|psi-mi:nadk-1(display_short)|uniprotkb:CELE_Y77E11A.2(orf name)|uniprotkb:Y77E11A.2(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537598|imex:IM-18681-458 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500084.2|wormbase:Y77E11A.2|ensemblmetazoa:WBGene00022307(gene)|ensemblmetazoa:Y77E11A.2.1(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|dip:DIP-24720N|uniprotkb:Q9N4A9(identity)|wormbase:WBGene00022307(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eKOdyVxVm1LzYJrijR/u4sVqYk86239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:23707952A856EEC6|rigid:qIPu9UFWE5ll1Xs/EGDiZZ5L8CI false - sufficient binding region:1040-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18683 uniprotkb:Q95XA9 intact:EBI-6537634|ensemblmetazoa:C47E12.2.1|ensemblmetazoa:C47E12.2.2 intact:EBI-6537613|ensemblmetazoa:Y20F4.3a.1|uniprotkb:G4SRM7 psi-mi:q18683_caeel(display_long)|uniprotkb:ADP,ATP carrier protein(gene name synonym)|uniprotkb:C47E12.2(orf name)|uniprotkb:CELE_C47E12.2(orf name) psi-mi:q95xa9_caeel(display_long)|uniprotkb:Y20F4.3(orf name)|uniprotkb:gap-3(gene name)|psi-mi:gap-3(display_short)|uniprotkb:CELE_Y20F4.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537630|imex:IM-18681-460 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C47E12.2.1(transcript)|ensemblmetazoa:C47E12.2.2(transcript)|ensemblmetazoa:WBGene00008147(gene)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|refseq:NP_501803.1|wormbase:C47E12.2|uniprotkb:Q18683(identity)|wormbase:WBGene00008147(identity) ensemblmetazoa:WBGene00021238(gene)|ensemblmetazoa:Y20F4.3a.1(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0043409"(negative regulation of MAPK cascade)|wormbase:Y20F4.3a|reactome:R-CEL-186763|reactome:R-CEL-8849471|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|refseq:NP_490916.5|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95XA9(identity)|wormbase:WBGene00021238(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:nEgCySXfjvXRLMIfcuXq10jz4u46239 rogid:W7Klw/TiaXQdDxym/p8FIth/Gn46239 intact-crc:BE0A4C3145226801|rigid:DO+iIg8B1+81FHwdt4IyjllTvsQ false - sufficient binding region:211-268 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XA9 uniprotkb:P90783 intact:EBI-6537613|ensemblmetazoa:Y20F4.3a.1|uniprotkb:G4SRM7 intact:EBI-323546|ensemblmetazoa:C55A6.9.1 psi-mi:q95xa9_caeel(display_long)|uniprotkb:Y20F4.3(orf name)|uniprotkb:gap-3(gene name)|psi-mi:gap-3(display_short)|uniprotkb:CELE_Y20F4.3(orf name) psi-mi:paf1_caeel(display_long)|uniprotkb:pafo-1(gene name)|psi-mi:pafo-1(display_short)|uniprotkb:C55A6.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537647|imex:IM-18681-461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021238(gene)|ensemblmetazoa:Y20F4.3a.1(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0043409"(negative regulation of MAPK cascade)|wormbase:Y20F4.3a|reactome:R-CEL-186763|reactome:R-CEL-8849471|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|refseq:NP_490916.5|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95XA9(identity)|wormbase:WBGene00021238(identity) refseq:NP_505925.1|wormbase:C55A6.9|ensemblmetazoa:C55A6.9.1(transcript)|ensemblmetazoa:WBGene00008338(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|interpro:IPR007133(RNA polymerase II-associated, Paf1)|dip:DIP-27306N|reactome:R-CEL-674695|reactome:R-CEL-75955|reactome:R-CEL-112382|uniprotkb:P90783(identity)|wormbase:WBGene00008338(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W7Klw/TiaXQdDxym/p8FIth/Gn46239 rogid:v0DY8i2fXfsy3ngWMjPqXNJvvUE6239 intact-crc:8A26D6F7DCB63E46|rigid:KUXG7hM4DQ80J2uEQbMPTfh5nho false sufficient binding region:211-268 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XA9 intact:EBI-6537666 intact:EBI-6537613|ensemblmetazoa:Y20F4.3a.1|uniprotkb:G4SRM7 - psi-mi:q95xa9_caeel(display_long)|uniprotkb:Y20F4.3(orf name)|uniprotkb:gap-3(gene name)|psi-mi:gap-3(display_short)|uniprotkb:CELE_Y20F4.3(orf name) psi-mi:q4w4y4_caeel(display_short)|psi-mi:EBI-6537666(display_long)|uniprotkb:CELE_E02D9.1(orf name)|uniprotkb:E02D9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537662|imex:IM-18681-462 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021238(gene)|ensemblmetazoa:Y20F4.3a.1(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0043409"(negative regulation of MAPK cascade)|wormbase:Y20F4.3a|reactome:R-CEL-186763|reactome:R-CEL-8849471|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|refseq:NP_490916.5|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95XA9(identity)|wormbase:WBGene00021238(identity) uniprotkb:Q4W4Y4(uniprot-removed-ac)|uniprotkb:Q4W4Y4(identity)|wormbase:WBGene00017098(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W7Klw/TiaXQdDxym/p8FIth/Gn46239 rogid:NIJWXkr9ktB8W0S/AsDXQVyQEYc6239 intact-crc:3E6B012623856705|rigid:clkAldBwhXp491x4JTaHVV2mAf8 false sufficient binding region:211-268 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19764 uniprotkb:Q95XA9 intact:EBI-326810|ensemblmetazoa:F23H12.5.1 intact:EBI-6537613|ensemblmetazoa:Y20F4.3a.1|uniprotkb:G4SRM7 psi-mi:q19764_caeel(display_long)|uniprotkb:F23H12.5(orf name)|uniprotkb:CELE_F23H12.5(orf name) psi-mi:q95xa9_caeel(display_long)|uniprotkb:Y20F4.3(orf name)|uniprotkb:gap-3(gene name)|psi-mi:gap-3(display_short)|uniprotkb:CELE_Y20F4.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537679|imex:IM-18681-463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506096.1|wormbase:F23H12.5|ensemblmetazoa:F23H12.5.1(transcript)|ensemblmetazoa:WBGene00009094(gene)|go:"GO:0007411"(axon guidance)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR027231|interpro:IPR036383|dip:DIP-27050N|uniprotkb:Q19764(identity)|wormbase:WBGene00009094(identity) ensemblmetazoa:WBGene00021238(gene)|ensemblmetazoa:Y20F4.3a.1(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0043409"(negative regulation of MAPK cascade)|wormbase:Y20F4.3a|reactome:R-CEL-186763|reactome:R-CEL-8849471|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|refseq:NP_490916.5|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95XA9(identity)|wormbase:WBGene00021238(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:87bx3XRancS2PP7X6EzpK22nFa86239 rogid:W7Klw/TiaXQdDxym/p8FIth/Gn46239 intact-crc:7363A292A86B801B|rigid:cKmLSrM7XDa60FwxvEbQaMjlsas false - sufficient binding region:211-268 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17491 uniprotkb:G5ECK4 intact:EBI-319244|ensemblmetazoa:B0393.2.1|ensemblmetazoa:B0393.2.2 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:q17491_caeel(display_long)|uniprotkb:rbg-3(gene name)|psi-mi:rbg-3(display_short)|uniprotkb:B0393.2(orf name)|uniprotkb:CELE_B0393.2(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537709|imex:IM-18681-465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497979.1|wormbase:B0393.2|ensemblmetazoa:B0393.2.1(transcript)|ensemblmetazoa:B0393.2.2(transcript)|ensemblmetazoa:WBGene00007167(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|dip:DIP-25279N|uniprotkb:Q17491(identity)|wormbase:WBGene00007167(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:z4wZZ/qpeyN2g1mI7LTzeXL+Zcg6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:7FE299A22BC00DEA|rigid:ivxsq1whlcaOYuPUnegrZUWF4zM false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09345 uniprotkb:Q95XA9 intact:EBI-2006279|ensemblmetazoa:R144.2a.1|ensemblmetazoa:R144.2a.2 intact:EBI-6537613|ensemblmetazoa:Y20F4.3a.1|uniprotkb:G4SRM7 psi-mi:pcf11_caeel(display_long)|uniprotkb:R144.2(orf name)|uniprotkb:pcf-11(gene name)|psi-mi:pcf-11(display_short) psi-mi:q95xa9_caeel(display_long)|uniprotkb:Y20F4.3(orf name)|uniprotkb:gap-3(gene name)|psi-mi:gap-3(display_short)|uniprotkb:CELE_Y20F4.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537694|imex:IM-18681-464 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498068.1|wormbase:R144.2a|interpro:IPR008942(ENTH/VHS)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|reactome:R-CEL-6807505|reactome:R-CEL-73856|ensemblmetazoa:R144.2a.1(transcript)|ensemblmetazoa:R144.2a.2(transcript)|ensemblmetazoa:WBGene00020092(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|uniprotkb:Q09345(identity)|wormbase:WBGene00020092(identity) ensemblmetazoa:WBGene00021238(gene)|ensemblmetazoa:Y20F4.3a.1(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0043409"(negative regulation of MAPK cascade)|wormbase:Y20F4.3a|reactome:R-CEL-186763|reactome:R-CEL-8849471|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|refseq:NP_490916.5|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95XA9(identity)|wormbase:WBGene00021238(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:XTyRR+k9dN5uoxwUXnAuM34SSUA6239 rogid:W7Klw/TiaXQdDxym/p8FIth/Gn46239 intact-crc:34AD442425C6C9AE|rigid:cmbDiStxXH7iKFfwPdPC8l8w1Ag false - sufficient binding region:211-268 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39055 uniprotkb:G5ECK4 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537724|imex:IM-18681-466 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 42|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:20A232454F75F464|rigid:1osvjpZSpAVuMsvcfbirh6m9Trk false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:O45134 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-324693|ensemblmetazoa:C05D2.5.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:o45134_caeel(display_long)|uniprotkb:xnd-1(gene name)|psi-mi:xnd-1(display_short)|uniprotkb:C05D2.5(orf name)|uniprotkb:CELE_C05D2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537739|imex:IM-18681-467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_498207.1|wormbase:C05D2.5|ensemblmetazoa:C05D2.5.1(transcript)|ensemblmetazoa:WBGene00001514(gene)|dip:DIP-24820N|uniprotkb:O45134(identity)|wormbase:WBGene00001514(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:lHZ09WJWDID3h3TwsWRPCx7SnBM6239 intact-crc:EB30668255F2E96F|rigid:P0H7Sq6r6CCS8L2R+nuEi/9sdQo false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECD7 uniprotkb:G5ECK4 intact:EBI-321964|ensemblmetazoa:C06C3.1c.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:g5ecd7_caeel(display_long)|uniprotkb:mel-11(gene name)|psi-mi:mel-11(display_short)|uniprotkb:C06C3.1(orf name)|uniprotkb:CELE_C06C3.1(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537754|imex:IM-18681-468 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-2565942|reactome:R-CEL-5627123|wormbase:C06C3.1c|uniprotkb:Q8I0N9(uniprot-removed-ac)|interpro:IPR031775|interpro:IPR002110(Ankyrin)|interpro:IPR020683|refseq:NP_001021928.1|ensemblmetazoa:C06C3.1c.1(transcript)|ensemblmetazoa:WBGene00003196(gene)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0048598"(embryonic morphogenesis)|reactome:R-CEL-5625740|interpro:IPR036770|uniprotkb:G5ECD7(identity)|wormbase:WBGene00003196(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:bGFxgXOiEstHHLok9wqg0GnsMJU6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:B7240473BC67AF8D|rigid:PIC4BZrXqLwQ1MB2uOrVSAR8pVY false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:D3KFW7 uniprotkb:G5ECK4 intact:EBI-6537769|ensemblmetazoa:C10C6.1b.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:d3kfw7_caeel(display_long)|uniprotkb:C10C6.1(orf name)|uniprotkb:kin-4(gene name)|psi-mi:kin-4(display_short)|uniprotkb:CELE_C10C6.1(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537771|imex:IM-18681-469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C10C6.1b.1(transcript)|ensemblmetazoa:WBGene00002192(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|refseq:NP_001255558.1|wormbase:C10C6.1b|interpro:IPR000719(Protein kinase, core)|interpro:IPR037711|interpro:IPR036034|interpro:IPR041489|uniprotkb:D3KFW7(identity)|wormbase:WBGene00002192(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 13|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:mm+V+kOH2814EdqmRz6NZF4ABvE6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:95B4A5233544F03B|rigid:l6sNfkhQO8uGsbZUVxOzLRdwqY8 false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:W6RRU8 uniprotkb:G5ECK4 intact:EBI-9510706|ensemblmetazoa:C49H3.5c.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:w6rru8_caeel(display_long)|uniprotkb:C49H3.5(orf name)|uniprotkb:ntl-4(gene name)|psi-mi:ntl-4(display_short)|uniprotkb:CELE_C49H3.5(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537786|imex:IM-18681-470 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|refseq:NP_001294150.1|interpro:IPR034261|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|wormbase:C49H3.5c|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|ensemblmetazoa:C49H3.5c.1(transcript)|ensemblmetazoa:WBGene00003827(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0046872"(metal ion binding)|uniprotkb:Q8T3E7(identity)|wormbase:WBGene00003827(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BLiHVWKDtmt8qFNWbfIPaJPOSwA6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:6A07371B28137470|rigid:dDlNz5XevbzZExDCwfYgTC1YyYg false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19289 uniprotkb:G5ECK4 intact:EBI-316236|uniprotkb:Q19290|uniprotkb:Q21063|ensemblmetazoa:F10C1.2b.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:ifb1_caeel(display_long)|uniprotkb:ifb-1(gene name)|psi-mi:ifb-1(display_short)|uniprotkb:F10C1.2(orf name)|uniprotkb:Intermediate filament protein B1(gene name synonym)|uniprotkb:Cel IF B1(gene name synonym) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537801|imex:IM-18681-471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495136.1|refseq:NP_495137.1|wormbase:F10C1.2a|wormbase:F10C1.2b|reactome:R-CEL-4419969|ensemblmetazoa:F10C1.2b.1(transcript)|ensemblmetazoa:WBGene00002053(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|dip:DIP-26309N|uniprotkb:Q19289(identity)|wormbase:WBGene00002053(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tTtvjq2kBdiUk2RWhrXUHC3+hvM6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:CFB9089953F3B1F1|rigid:8YTWsXx6Tlts4bl2Iap9ib6ba8U false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q7JP65 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-6532045|ensemblmetazoa:F10D7.5b.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q7jp65_caeel(display_long)|uniprotkb:CELE_F10D7.5(orf name)|uniprotkb:F10D7.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537816|imex:IM-18681-472 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) ensemblmetazoa:F10D7.5b.1(transcript)|ensemblmetazoa:WBGene00017342(gene)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006573(NEUZ)|refseq:NP_510817.3|wormbase:F10D7.5b|interpro:IPR037962|interpro:IPR043136|uniprotkb:Q7JP65(identity)|wormbase:WBGene00017342(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:dmeTGxA1egh7S0o5roMacNRvJzA6239 intact-crc:8C3CF4CEB24F2E98|rigid:NvZwW4bIbbdOPOQeonXs6E0QhmE false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:P34397 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-321990|ensemblmetazoa:F10E9.3.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:ylu3_caeel(display_long)|uniprotkb:F10E9.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537831|imex:IM-18681-473 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_498826.2|wormbase:F10E9.3|ensemblmetazoa:F10E9.3.1(transcript)|ensemblmetazoa:WBGene00017355(gene)|interpro:IPR040437|dip:DIP-26529N|uniprotkb:P34397(identity)|wormbase:WBGene00017355(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:rI7gLX2TWTqguT53dk5CTySk7to6239 intact-crc:5715D398823F8C58|rigid:59X++4KKSEDehdxDu/kKl/hQGYQ false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:G5ED57 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-327853|ensemblmetazoa:F22E12.1.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:g5ed57_caeel(display_long)|uniprotkb:F22E12.1(orf name)|uniprotkb:CELE_F22E12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537846|imex:IM-18681-474 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) uniprotkb:O45916(uniprot-removed-ac)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR020901|refseq:NP_505684.2|wormbase:F22E12.1|ensemblmetazoa:F22E12.1.1(transcript)|ensemblmetazoa:WBGene00009058(gene)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036880|uniprotkb:G5ED57(identity)|wormbase:WBGene00009058(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:+Rdyx7pnykvpAExFI2L56AHfbIc6239 intact-crc:69B14F409B7ED5DF|rigid:6TA1+N9gqbkrWEbDUE/4vkOL8jk false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:O16299 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537876|imex:IM-18681-476 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 16|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 intact-crc:D812A1A9197CAE79|rigid:b2wQFjfZwDlnMIi4zzKDQdW8F7s false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:E3W743 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537861|imex:IM-18681-475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 intact-crc:33794E0E2436D690|rigid:4ypt53Ki7nwqFjWhfLCKWzxJDlk false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q20330 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-322042|ensemblmetazoa:F42C5.10.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q20330_caeel(display_long)|uniprotkb:ifo-1(gene name)|psi-mi:ifo-1(display_short)|uniprotkb:ttm-4(gene name synonym)|uniprotkb:CELE_F42C5.10(orf name)|uniprotkb:F42C5.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537891|imex:IM-18681-477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_501170.1|wormbase:F42C5.10|ensemblmetazoa:F42C5.10.1(transcript)|ensemblmetazoa:WBGene00018350(gene)|dip:DIP-27375N|uniprotkb:Q20330(identity)|wormbase:WBGene00018350(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:G/TdIwuOTGQMqaW/I1aJ4GvrtlU6239 intact-crc:D2526DFE649B4C89|rigid:FMqCt4yVAHxiF76aoQ55ekGuhuM false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q9U3F4 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-322208|ensemblmetazoa:F42G4.3a.1|ensemblmetazoa:F42G4.3a.2|intact:EBI-6726473|uniprotkb:H2L2F5|uniprotkb:H2L2F6|uniprotkb:H2L2F7|uniprotkb:Q9U3F5 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:zyx_caeel(display_long)|uniprotkb:zyx-1(gene name)|psi-mi:zyx-1(display_short)|uniprotkb:F42G4.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537906|imex:IM-18681-478 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_496776.1|wormbase:F42G4.3a|refseq:NP_001254364.1|refseq:NP_001254365.1|refseq:NP_001254366.1|refseq:NP_496777.2|ensemblmetazoa:F42G4.3a.1(transcript)|ensemblmetazoa:F42G4.3a.2(transcript)|ensemblmetazoa:WBGene00006999(gene)|go:"GO:0000003"(reproduction)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0030424"(axon)|go:"GO:0031430"(M band)|go:"GO:0046872"(metal ion binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0099558"(maintenance of synapse structure)|interpro:IPR001781(Zinc finger, LIM-type)|wormbase:F42G4.3b|wormbase:F42G4.3c|wormbase:F42G4.3d|wormbase:F42G4.3e|dip:DIP-25080N|reactome:R-CEL-446353|uniprotkb:Q9U3F4(identity)|wormbase:WBGene00006999(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:exwjcy8wa6wyQDjjrsMqV8rjUc86239 intact-crc:6573C2C354EF17FD|rigid:/j89ONB28wYJ0pgA9Bkud0RZQdQ false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q20877 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-315480|ensemblmetazoa:F56D3.1.1|ensemblmetazoa:F56D3.1.2 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q20877_caeel(display_long)|uniprotkb:F56D3.1(orf name)|uniprotkb:CELE_F56D3.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537921|imex:IM-18681-479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_494727.1|wormbase:F56D3.1|ensemblmetazoa:F56D3.1.1(transcript)|ensemblmetazoa:F56D3.1.2(transcript)|ensemblmetazoa:WBGene00018969(gene)|dip:DIP-24648N|uniprotkb:Q20877(identity)|wormbase:WBGene00018969(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:AUv5Clc1XXnuucrO63ViEf7UQV46239 intact-crc:4FCE703BBA9C9AB5|rigid:xMygqtv+ywq6nP4wvrWxhM69PFY false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:O01900 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537936|imex:IM-18681-480 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 intact-crc:245344C24DC8E3A4|rigid:86JuMVwIRQWQMDTElB4+US3w2So false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:O17214 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-319290|ensemblmetazoa:H14A12.2a.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:fumh_caeel(display_long)|uniprotkb:H14A12.2(orf name)|uniprotkb:fum-1(gene name)|psi-mi:fum-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537951|imex:IM-18681-481 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) ensemblmetazoa:H14A12.2a.1(transcript)|ensemblmetazoa:WBGene00001503(gene)|go:"GO:0004333"(fumarate hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|interpro:IPR020557|interpro:IPR022761|interpro:IPR024083|refseq:NP_498642.1|wormbase:H14A12.2a|reactome:R-CEL-71403|dip:DIP-25418N|uniprotkb:O17214(identity)|wormbase:WBGene00001503(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:fFt+5dBFVE2bfEfITZ0ZA6MjVI46239 intact-crc:80B2749DDD875372|rigid:jakAdsqYS8pEBUir+qkN6Vvecsc false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:G5ECL2 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537966|imex:IM-18681-482 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 intact-crc:C48FA66D7B4B594F|rigid:BoXbf6GxpIiSjRP2BdXR1gh4Aak false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6537981 uniprotkb:G5ECK4 - intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:q1nz34_caeel(display_short)|psi-mi:EBI-6537981(display_long)|uniprotkb:CELE_R07G3.3(orf name)|uniprotkb:npp-21(gene name)|psi-mi:npp-21(display_short)|uniprotkb:R07G3.3(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537983|imex:IM-18681-483 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q1NZ34(uniprot-removed-ac)|uniprotkb:Q1NZ34(identity)|wormbase:WBGene00019940(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:i4+jP7pvB7mO051qdSQnptuHhsM6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:83E6CCBBBCE08544|rigid:pOU/uV7AqXV4F3hRhhsKAFC5l1o false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:G5EFY6 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-317770|ensemblmetazoa:T01G1.3.1|ensemblmetazoa:T01G1.3.2|ensemblmetazoa:T01G1.3.3 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:g5efy6_caeel(display_long)|uniprotkb:T01G1.3(orf name)|uniprotkb:sec-31(gene name)|psi-mi:sec-31(display_short)|uniprotkb:CELE_T01G1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6537998|imex:IM-18681-484 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) uniprotkb:O45604(uniprot-removed-ac)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_502144.1|interpro:IPR040251|reactome:R-CEL-204005|wormbase:T01G1.3|ensemblmetazoa:T01G1.3.1(transcript)|ensemblmetazoa:T01G1.3.2(transcript)|ensemblmetazoa:T01G1.3.3(transcript)|ensemblmetazoa:WBGene00011338(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR036322|uniprotkb:G5EFY6(identity)|wormbase:WBGene00011338(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:FVZWQhc6ZjDGweaz8DeSFuMo9Zg6239 intact-crc:84733A8C8CDFEC2C|rigid:S3K7W6DSXU1zdNxEQBK87US31SM false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:P91482 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-315371|ensemblmetazoa:T20F5.6.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:p91482_caeel(display_long)|uniprotkb:T20F5.6(orf name)|uniprotkb:CELE_T20F5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538013|imex:IM-18681-485 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_491266.1|wormbase:T20F5.6|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|ensemblmetazoa:T20F5.6.1(transcript)|ensemblmetazoa:WBGene00020628(gene)|go:"GO:0046872"(metal ion binding)|uniprotkb:P91482(identity)|wormbase:WBGene00020628(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:XgUfhY6bbYdTU31B8yVQiDR2+KA6239 intact-crc:5D49BACC0E10AD40|rigid:0MHD909Gu6QEU2mDdHBwdNaywXQ false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91820 uniprotkb:G5ECK4 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538028|imex:IM-18681-486 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N|uniprotkb:P91820(identity)|wormbase:WBGene00003083(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:8BE37D1D537C5810|rigid:xi9IF6AOTxeyShdpGKVbyc/opTg false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 intact:EBI-6534333 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 - psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q965y4_caeel(display_short)|psi-mi:EBI-6534333(display_long)|uniprotkb:Y110A2AM.1(gene name)|psi-mi:Y110A2AM.1(display_short)|uniprotkb:CELE_Y110A2AM.1(orf name)|uniprotkb:Y110A2AM.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538043|imex:IM-18681-487 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) uniprotkb:Q965Y4(uniprot-removed-ac)|uniprotkb:Q965Y4(identity)|wormbase:WBGene00022449(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:zqy/LYo1vjSCTC0G4hp+sZ4vti06239 intact-crc:B4B1F2AF6BBC7282|rigid:IxeWD4tX3ItpJGehnuIdIZU3H2Y false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q9XWN1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-324865|ensemblmetazoa:Y43F8C.6a.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q9xwn1_caeel(display_long)|uniprotkb:Y43F8C.6(orf name)|uniprotkb:CELE_Y43F8C.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538058|imex:IM-18681-488 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_001256880.1|wormbase:Y43F8C.6a|ensemblmetazoa:WBGene00012828(gene)|ensemblmetazoa:Y43F8C.6a.1(transcript)|go:"GO:0016589"(NURF complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR037931|dip:DIP-27198N|uniprotkb:Q9XWN1(identity)|wormbase:WBGene00012828(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:BnRBxnWaRRWRCAx+LGlNwRaOcOU6239 intact-crc:87504BE23E523A47|rigid:Oth5jGe9iECQlYIQMycGqO6fInI false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q4VNJ8 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-2918529 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538090|imex:IM-18681-490 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 intact-crc:B6913AE4079392BE|rigid:yu/KpmobzXUAKwnCTrGyX6InRC8 false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:V6CKC3 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-6538077|ensemblmetazoa:Y48G8AL.10a.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:v6ckc3_caeel(display_long)|uniprotkb:znf-236(gene name)|psi-mi:znf-236(display_short)|uniprotkb:CELE_Y48G8AL.10(orf name)|uniprotkb:Y48G8AL.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538073|imex:IM-18681-489 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) reactome:R-CEL-111367|reactome:R-CEL-73856|reactome:R-CEL-77588|ensemblmetazoa:WBGene00021689(gene)|ensemblmetazoa:Y48G8AL.10a.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_001293225.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|wormbase:Y48G8AL.10a|interpro:IPR036236|uniprotkb:Q9BL20(identity)|wormbase:WBGene00021689(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:untbXZe0VJLK0UhnM5vZA+ORfyU6239 intact-crc:8CD04C93EDCF7D0F|rigid:8REszQm+mQj8Dtckeq3zwzz+oYg false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8I4E2 uniprotkb:P39055 intact:EBI-4325777|uniprotkb:D3NQ98|uniprotkb:J7SA60|uniprotkb:Q8I4E1|uniprotkb:Q9XXG2|uniprotkb:Q9XXG3|ensemblmetazoa:Y37A1B.2c.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:lst4_caeel(display_long)|uniprotkb:lst-4(gene name)|psi-mi:lst-4(display_short)|uniprotkb:Lateral signaling target protein 4(gene name synonym)|uniprotkb:Y37A1B.2(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538105|imex:IM-18681-491 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036871|interpro:IPR027267|interpro:IPR036028|wormbase:Y37A1B.2d|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|reactome:R-CEL-8856828|refseq:NP_502693.2|wormbase:Y37A1B.2a|wormbase:Y37A1B.2b|wormbase:Y37A1B.2c|wormbase:Y37A1B.2e|wormbase:Y37A1B.2f|refseq:NP_001255779.1|refseq:NP_001263811.1|refseq:NP_502694.1|refseq:NP_502695.2|refseq:NP_872090.1|reactome:R-CEL-432722|go:"GO:0032009"(early phagosome)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045335"(phagocytic vesicle)|ensemblmetazoa:WBGene00003086(gene)|ensemblmetazoa:Y37A1B.2c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0090389"(phagosome-lysosome fusion involved in apoptotic cell clearance)|go:"GO:0097194"(execution phase of apoptosis) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:NqGhrxQdIIT2DDOgu+/swsZFniQ6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:E247CE6A6AF9C39E|rigid:BznmhiVYxKJWY3voUGDupXIylo4 false sufficient binding region:2-60 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8I4E2 uniprotkb:O16299 intact:EBI-4325777|uniprotkb:D3NQ98|uniprotkb:J7SA60|uniprotkb:Q8I4E1|uniprotkb:Q9XXG2|uniprotkb:Q9XXG3|ensemblmetazoa:Y37A1B.2c.1 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 psi-mi:lst4_caeel(display_long)|uniprotkb:lst-4(gene name)|psi-mi:lst-4(display_short)|uniprotkb:Lateral signaling target protein 4(gene name synonym)|uniprotkb:Y37A1B.2(orf name) psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538120|imex:IM-18681-492 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036871|interpro:IPR027267|interpro:IPR036028|wormbase:Y37A1B.2d|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|reactome:R-CEL-8856828|refseq:NP_502693.2|wormbase:Y37A1B.2a|wormbase:Y37A1B.2b|wormbase:Y37A1B.2c|wormbase:Y37A1B.2e|wormbase:Y37A1B.2f|refseq:NP_001255779.1|refseq:NP_001263811.1|refseq:NP_502694.1|refseq:NP_502695.2|refseq:NP_872090.1|reactome:R-CEL-432722|go:"GO:0032009"(early phagosome)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045335"(phagocytic vesicle)|ensemblmetazoa:WBGene00003086(gene)|ensemblmetazoa:Y37A1B.2c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0090389"(phagosome-lysosome fusion involved in apoptotic cell clearance)|go:"GO:0097194"(execution phase of apoptosis) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 118|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:NqGhrxQdIIT2DDOgu+/swsZFniQ6239 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 intact-crc:34BB2119049FEB6B|rigid:jmrhIUnEZftAg0ZoC2Sd6c2kvzc false sufficient binding region:2-60 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL2 uniprotkb:Q8I4E2 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 intact:EBI-4325777|uniprotkb:D3NQ98|uniprotkb:J7SA60|uniprotkb:Q8I4E1|uniprotkb:Q9XXG2|uniprotkb:Q9XXG3|ensemblmetazoa:Y37A1B.2c.1 psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:lst4_caeel(display_long)|uniprotkb:lst-4(gene name)|psi-mi:lst-4(display_short)|uniprotkb:Lateral signaling target protein 4(gene name synonym)|uniprotkb:Y37A1B.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538135|imex:IM-18681-493 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) interpro:IPR036871|interpro:IPR027267|interpro:IPR036028|wormbase:Y37A1B.2d|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|reactome:R-CEL-8856828|refseq:NP_502693.2|wormbase:Y37A1B.2a|wormbase:Y37A1B.2b|wormbase:Y37A1B.2c|wormbase:Y37A1B.2e|wormbase:Y37A1B.2f|refseq:NP_001255779.1|refseq:NP_001263811.1|refseq:NP_502694.1|refseq:NP_502695.2|refseq:NP_872090.1|reactome:R-CEL-432722|go:"GO:0032009"(early phagosome)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045335"(phagocytic vesicle)|ensemblmetazoa:WBGene00003086(gene)|ensemblmetazoa:Y37A1B.2c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0090389"(phagosome-lysosome fusion involved in apoptotic cell clearance)|go:"GO:0097194"(execution phase of apoptosis) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 84|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 rogid:NqGhrxQdIIT2DDOgu+/swsZFniQ6239 intact-crc:6329763EFC9E8D70|rigid:jbu70655i4R8/whr1fkgxLvbG30 false - sufficient binding region:2-60 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:Q19749 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538167|imex:IM-18681-495 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N|uniprotkb:Q19749(identity)|wormbase:WBGene00009082(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 22|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 intact-crc:7D08DBBFAA7CBE96|rigid:LuGm4fbicSERO6C/URUlIvqop8g false sufficient binding region:62-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:Q17865 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538152|imex:IM-18681-494 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 37|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:1498B4358986B73B|rigid:RtBZNYhi8VdEOFqt3HRiwEGT0U0 false sufficient binding region:62-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21234 uniprotkb:Q9N415 intact:EBI-322058|ensemblmetazoa:K04G7.1.1|ensemblmetazoa:K04G7.1.2 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 psi-mi:q21234_caeel(display_long)|uniprotkb:K04G7.1(orf name)|uniprotkb:CELE_K04G7.1(orf name) psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538182|imex:IM-18681-496 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498567.1|wormbase:K04G7.1|ensemblmetazoa:K04G7.1.1(transcript)|ensemblmetazoa:K04G7.1.2(transcript)|ensemblmetazoa:WBGene00019400(gene)|interpro:IPR041588|dip:DIP-24838N|uniprotkb:Q21234(identity)|wormbase:WBGene00019400(identity) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:CrlqZaC+CNbM7spMqFaHku8bdRI6239 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 intact-crc:55C7D77313F640CC|rigid:zwF636mLRLb2k2CrkLpeftxVFJw false - sufficient binding region:62-126 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:Q9XX15 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-6538212|ensemblmetazoa:Y39A1A.14.1 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:nep1_caeel(display_long)|uniprotkb:Ribosome biogenesis protein nep-1(gene name synonym)|uniprotkb:Y39A1A.14(orf name)|uniprotkb:"18S rRNA (pseudouridine-N1)-methyltransferase"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538214|imex:IM-18681-498 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) ensemblmetazoa:WBGene00012652(gene)|ensemblmetazoa:Y39A1A.14.1(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0070037"("rRNA (pseudouridine) methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|wormbase:Y39A1A.14|interpro:IPR029026|interpro:IPR005304(Suppressor Mra1)|refseq:NP_499349.1|interpro:IPR029028|reactome:R-CEL-6791226|uniprotkb:Q9XX15(identity)|wormbase:WBGene00012652(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:O+XCHnpQ3yCLvffCll3+QpNoVoo6239 intact-crc:243E47C2943DF5E9|rigid:F2/Fu/udMeE/6mPvbd/KtYoBxtk false sufficient binding region:62-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 intact:EBI-329520 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 - psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:o02165_caeel(display_short)|psi-mi:EBI-329520(display_long)|uniprotkb:T20F7.5(orf name)|uniprotkb:CELE_T20F7.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538197|imex:IM-18681-497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) uniprotkb:O02165(uniprot-removed-ac)|uniprotkb:O02165(identity)|wormbase:WBGene00020632(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:Xgt15U26ozDQ6/jYEE9omKoKmQw6239 intact-crc:905D1BFDB63FB411|rigid:uhv+9gtYC/H6JOYfRB8SHYKhK6g false sufficient binding region:62-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:P10567 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-318168|uniprotkb:Q93214|uniprotkb:Q93439|ensemblmetazoa:F07A5.7a.1|ensemblmetazoa:F07A5.7a.2|ensemblmetazoa:F07A5.7a.3|ensemblmetazoa:F07A5.7a.4|intact:EBI-11465138|intact:EBI-11466975|intact:EBI-6460025|uniprotkb:B3WFV3 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:mysp_caeel(display_long)|uniprotkb:unc-15(gene name)|psi-mi:unc-15(display_short)|uniprotkb:F07A5.7(orf name)|uniprotkb:Uncoordinated protein 15(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538244|imex:IM-18681-500 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) refseq:NP_492085.1|wormbase:F07A5.7a|ensemblmetazoa:F07A5.7a.1(transcript)|ensemblmetazoa:F07A5.7a.2(transcript)|ensemblmetazoa:F07A5.7a.3(transcript)|ensemblmetazoa:F07A5.7a.4(transcript)|ensemblmetazoa:WBGene00006754(gene)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016459"(myosin complex)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032982"(myosin filament)|go:"GO:0040011"(locomotion)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0060279"(positive regulation of ovulation)|go:"GO:0060298"(positive regulation of sarcomere organization)|interpro:IPR002928(Myosin tail)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|refseq:NP_001129763.1|wormbase:F07A5.7b|dip:DIP-24443N|uniprotkb:P10567(identity)|wormbase:WBGene00006754(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2017/02/23 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:qDSWRA42Ad8ZvgnKN1TomAfe1f46239 intact-crc:9905DB67B5250571|rigid:RZdGd2VNCP6vlQYsZBdGEhi4Cw4 false sufficient binding region:816-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:Q17865 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538229|imex:IM-18681-499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 53|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:6081019247AA5F21|rigid:RtBZNYhi8VdEOFqt3HRiwEGT0U0 false sufficient binding region:816-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:Q8MQ71 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-6538263|ensemblmetazoa:F19C7.8b.1 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:q8mq71_caeel(display_long)|uniprotkb:CELE_F19C7.8(orf name)|uniprotkb:F19C7.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538259|imex:IM-18681-501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) ensemblmetazoa:F19C7.8b.1(transcript)|ensemblmetazoa:WBGene00017597(gene)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR039688|refseq:NP_741381.1|wormbase:F19C7.8b|uniprotkb:Q8MQ71(identity)|wormbase:WBGene00017597(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:mg32XU6l6Kkuon9EELwfqIpPP9o6239 intact-crc:611FEA88A74137D0|rigid:rakixZyaniafks/3iJulGRsrvXs false sufficient binding region:816-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20010 uniprotkb:Q9N415 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538276|imex:IM-18681-502 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N|uniprotkb:Q20010(identity)|wormbase:WBGene00009385(identity) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 intact-crc:BF9DEC3D40835CFF|rigid:+mo7+Id2KN8g6rjOgA+oWZ0u8tI false - sufficient binding region:816-879 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21234 uniprotkb:Q9N415 intact:EBI-322058|ensemblmetazoa:K04G7.1.1|ensemblmetazoa:K04G7.1.2 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 psi-mi:q21234_caeel(display_long)|uniprotkb:K04G7.1(orf name)|uniprotkb:CELE_K04G7.1(orf name) psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538291|imex:IM-18681-503 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498567.1|wormbase:K04G7.1|ensemblmetazoa:K04G7.1.1(transcript)|ensemblmetazoa:K04G7.1.2(transcript)|ensemblmetazoa:WBGene00019400(gene)|interpro:IPR041588|dip:DIP-24838N|uniprotkb:Q21234(identity)|wormbase:WBGene00019400(identity) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 81|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:CrlqZaC+CNbM7spMqFaHku8bdRI6239 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 intact-crc:E379622417FAC02E|rigid:zwF636mLRLb2k2CrkLpeftxVFJw false - sufficient binding region:816-879 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:Q17865 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538321|imex:IM-18681-505 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 50|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:44357D6BBC0F6EB9|rigid:RtBZNYhi8VdEOFqt3HRiwEGT0U0 false sufficient binding region:1152-1216 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-329520 uniprotkb:Q9N415 - intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 psi-mi:o02165_caeel(display_short)|psi-mi:EBI-329520(display_long)|uniprotkb:T20F7.5(orf name)|uniprotkb:CELE_T20F7.5(orf name) psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538306|imex:IM-18681-504 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O02165(uniprot-removed-ac)|uniprotkb:O02165(identity)|wormbase:WBGene00020632(identity) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:Xgt15U26ozDQ6/jYEE9omKoKmQw6239 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 intact-crc:EE7A6922A62EFDB9|rigid:uhv+9gtYC/H6JOYfRB8SHYKhK6g false - sufficient binding region:816-879 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XTF3 uniprotkb:Q9N415 intact:EBI-2005616|uniprotkb:H9G2V8|uniprotkb:H9G2V9|uniprotkb:J7SF89|uniprotkb:Q27GP3|uniprotkb:Q2EEP1|uniprotkb:Q9TVF4|uniprotkb:Q20604|intact:EBI-2476794|ensemblmetazoa:F49E11.1b.1 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 psi-mi:mbk2_caeel(display_long)|uniprotkb:mbk-2(gene name)|psi-mi:mbk-2(display_short)|uniprotkb:F49E11.1(orf name)|uniprotkb:Minibrain Kinase 2(gene name synonym)|uniprotkb:Dual specificity Yak1-related kinase mbk-2(gene name synonym) psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538336|imex:IM-18681-506 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023207.1|refseq:NP_001023208.1|refseq:NP_001040950.1|refseq:NP_001040951.1|refseq:NP_502492.2|wormbase:F49E11.1a|wormbase:F49E11.1b|wormbase:F49E11.1c|wormbase:F49E11.1d|wormbase:F49E11.1e|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|wormbase:F49E11.1f|wormbase:F49E11.1g|wormbase:F49E11.1h|refseq:NP_001255694.1|refseq:NP_001255695.1|refseq:NP_001263802.1|interpro:IPR042521|ensemblmetazoa:F49E11.1b.1(transcript)|ensemblmetazoa:WBGene00003150(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000793"(condensed chromosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903864"(P granule disassembly)|uniprotkb:Q9XTF3(identity)|wormbase:WBGene00003150(identity) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 64|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:e0FXCawkUfjiG3D8gHgm4cJMoOU6239 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 intact-crc:0842187805F7C1C3|rigid:71zWgIcyw3zlJlJomJDN8SGp/yI false - sufficient binding region:1152-1216 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 intact:EBI-329520 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 - psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:o02165_caeel(display_short)|psi-mi:EBI-329520(display_long)|uniprotkb:T20F7.5(orf name)|uniprotkb:CELE_T20F7.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538351|imex:IM-18681-507 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) uniprotkb:O02165(uniprot-removed-ac)|uniprotkb:O02165(identity)|wormbase:WBGene00020632(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:Xgt15U26ozDQ6/jYEE9omKoKmQw6239 intact-crc:A2C3BF5D775D52FB|rigid:uhv+9gtYC/H6JOYfRB8SHYKhK6g false sufficient binding region:1152-1216 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NA98 uniprotkb:Q9N415 intact:EBI-316332|ensemblmetazoa:Y53F4B.22a.1|ensemblmetazoa:Y53F4B.22a.2 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 psi-mi:q9na98_caeel(display_long)|uniprotkb:arp-1(gene name)|psi-mi:arp-1(display_short)|uniprotkb:CELE_Y53F4B.22(orf name)|uniprotkb:Y53F4B.22(orf name) psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538366|imex:IM-18681-508 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497108.2|wormbase:Y53F4B.22a|ensemblmetazoa:WBGene00013168(gene)|ensemblmetazoa:Y53F4B.22a.1(transcript)|ensemblmetazoa:Y53F4B.22a.2(transcript)|go:"GO:0005869"(dynactin complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR043129|reactome:R-CEL-6798695|dip:DIP-26378N|reactome:R-CEL-6807878|reactome:R-CEL-6811436|reactome:R-CEL-3371497|uniprotkb:Q9NA98(identity)|wormbase:WBGene00013168(identity) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:P6kXOQimRLjJCMxrPfKTcTT5ig06239 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 intact-crc:6889811B6631BECD|rigid:5+FvGAcggJ7AE20OXdvgSg0D8D0 false - sufficient binding region:1152-1216 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NHC3 uniprotkb:Q23050 intact:EBI-6390681|ensemblmetazoa:Y41D4B.13a.1 intact:EBI-326596|ensemblmetazoa:T25F10.6a.1|ensemblmetazoa:T25F10.6a.2 psi-mi:ced2_caeel(display_long)|uniprotkb:ced-2(gene name)|psi-mi:ced-2(display_short)|uniprotkb:Cell-corpse engulfment protein CED-2(gene name synonym)|uniprotkb:Y41D4B.13(orf name) psi-mi:q23050_caeel(display_long)|uniprotkb:clik-1(gene name)|psi-mi:clik-1(display_short)|uniprotkb:CELE_T25F10.6(orf name)|uniprotkb:T25F10.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538396|imex:IM-18681-510 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000416(gene)|ensemblmetazoa:Y41D4B.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0012501"(programmed cell death)|go:"GO:0016477"(cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|rcsb pdb:3QWX|rcsb pdb:3QWY|reactome:R-CEL-186763|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-8849471|reactome:R-CEL-912631|refseq:NP_500105.1|wormbase:Y41D4B.13a|dip:DIP-25408N|uniprotkb:Q9NHC3(identity)|wormbase:WBGene00000416(identity) refseq:NP_001024158.1|wormbase:T25F10.6a|ensemblmetazoa:T25F10.6a.1(transcript)|ensemblmetazoa:T25F10.6a.2(transcript)|ensemblmetazoa:WBGene00020808(gene)|interpro:IPR000557(Calponin repeat)|dip:DIP-27445N|reactome:R-CEL-114608|uniprotkb:Q23050(identity)|wormbase:WBGene00020808(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:j5cxzcKENbxLxYp0CEUCAXlsmTk6239 rogid:CJGK9iuGtzmGkvXphcPiglOyZdw6239 intact-crc:598162B58E446716|rigid:2b02UhBrwFOmyuj4X7E/lYciBRU false sufficient binding region:219-276 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34574 uniprotkb:Q9NHC3 intact:EBI-319001|ensemblmetazoa:T20G5.1.1 intact:EBI-6390681|ensemblmetazoa:Y41D4B.13a.1 psi-mi:clh_caeel(display_long)|uniprotkb:T20G5.1(orf name)|uniprotkb:chc-1(gene name)|psi-mi:chc-1(display_short) psi-mi:ced2_caeel(display_long)|uniprotkb:ced-2(gene name)|psi-mi:ced-2(display_short)|uniprotkb:Cell-corpse engulfment protein CED-2(gene name synonym)|uniprotkb:Y41D4B.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538381|imex:IM-18681-509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499260.1|wormbase:T20G5.1|ensemblmetazoa:T20G5.1.1(transcript)|ensemblmetazoa:WBGene00011867(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|reactome:R-CEL-9013420|reactome:R-CEL-9013424|mint:P34574|dip:DIP-25251N|uniprotkb:P34574(identity)|wormbase:WBGene00011867(identity) ensemblmetazoa:WBGene00000416(gene)|ensemblmetazoa:Y41D4B.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0012501"(programmed cell death)|go:"GO:0016477"(cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|rcsb pdb:3QWX|rcsb pdb:3QWY|reactome:R-CEL-186763|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-8849471|reactome:R-CEL-912631|refseq:NP_500105.1|wormbase:Y41D4B.13a|dip:DIP-25408N|uniprotkb:Q9NHC3(identity)|wormbase:WBGene00000416(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 46|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:vbsqblpJ1wK5hEo5r2k/9giBsVI6239 rogid:j5cxzcKENbxLxYp0CEUCAXlsmTk6239 intact-crc:3496258508185E24|rigid:kMHiUL2Y1i/4Fc8fk8Z5RsXhGCM false - sufficient binding region:219-276 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:G5EC32 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538426|imex:IM-18681-512 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:A7C18F839792EC81|rigid:1czevcAqxE6Xv/WTTJk2lwhehRM false - sufficient binding region:151-207 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01900 uniprotkb:G5EC32 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538411|imex:IM-18681-511 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 26|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:39C9C0837BE8787D|rigid:XrhJYxh5OnmmNiHRYrKlGYuiVNI false - sufficient binding region:89-144 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q18605 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-331810|ensemblmetazoa:C44B9.4.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:q18605_caeel(display_long)|uniprotkb:athp-1(gene name)|psi-mi:athp-1(display_short)|uniprotkb:CELE_C44B9.4(orf name)|uniprotkb:C44B9.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538441|imex:IM-18681-513 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_499397.2|wormbase:C44B9.4|dip:DIP-27259N|ensemblmetazoa:C44B9.4.1(transcript)|ensemblmetazoa:WBGene00008081(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR042163|uniprotkb:Q18605(identity)|wormbase:WBGene00008081(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 46|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:H5ZuRoDCv1AIMpTM9EehO/NyVd86239 intact-crc:C4FD788E1F5F050F|rigid:kplwlbLZFHDC0IZ4Z9AMdnqd5ts false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9TYS1 uniprotkb:G5EC32 intact:EBI-321736|ensemblmetazoa:D1037.1.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:q9tys1_caeel(display_long)|uniprotkb:D1037.1(orf name)|uniprotkb:CELE_D1037.1(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538456|imex:IM-18681-514 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491200.1|wormbase:D1037.1|ensemblmetazoa:D1037.1.1(transcript)|ensemblmetazoa:WBGene00017025(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000467(D111/G-patch)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032922|dip:DIP-25428N|uniprotkb:Q9TYS1(identity)|wormbase:WBGene00017025(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:BYcktBm9BFEexLqJMazfrDsQoMM6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:4F00BE4331DE216E|rigid:qAsdEGSq63QOCo4K43XBeQ22EZU false - sufficient binding region:151-207 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:O61701 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-6537266 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:o61701_caeel(display_long)|uniprotkb:cyk-1(gene name)|psi-mi:cyk-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538471|imex:IM-18681-515 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) go:"GO:0003779"(actin binding)|go:"GO:0016043"(cellular component organization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|uniprotkb:O61701(identity)|wormbase:WBGene00000872(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 26|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:3tZm/rdSqLAK4eIpP1J9faYAo7w6239 intact-crc:96A41DD6507AF6D2|rigid:JFCbxLBhFAulffc33nL1WjOo+uk false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:O01900 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538486|imex:IM-18681-516 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 intact-crc:9416905463CA8EFF|rigid:XrhJYxh5OnmmNiHRYrKlGYuiVNI false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:P34552 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-322767|uniprotkb:Q7YXC7|uniprotkb:Q8I114|uniprotkb:Q8I115|uniprotkb:Q94159|ensemblmetazoa:R10E12.1b.1|ensemblmetazoa:R10E12.1b.2 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:alxa_caeel(display_long)|uniprotkb:alx-1(gene name)|psi-mi:alx-1(display_short)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 58"(gene name synonym)|uniprotkb:Protein YNK1(gene name synonym)|uniprotkb:pqn-58(gene name synonym)|uniprotkb:R10E12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538501|imex:IM-18681-517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_001022713.1|refseq:NP_001022714.1|refseq:NP_001022715.1|refseq:NP_499213.1|wormbase:R10E12.1a|wormbase:R10E12.1b|wormbase:R10E12.1c|wormbase:R10E12.1d|interpro:IPR004328(BRO1)|interpro:IPR025304|ensemblmetazoa:R10E12.1b.1(transcript)|ensemblmetazoa:R10E12.1b.2(transcript)|ensemblmetazoa:WBGene00007010(gene)|go:"GO:0005112"(Notch binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0007032"(endosome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043226"(organelle)|go:"GO:0055037"(recycling endosome)|interpro:IPR038499|uniprotkb:P34552(identity)|wormbase:WBGene00007010(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 29|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:xedXAHU8Ms6VcKj1w9YZDHURHHg6239 intact-crc:B6A4135A9D05C945|rigid:f8wYPNP6Tzmn7zKr3KGqAFPo9eU false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:A5PEX6 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-6532321|ensemblmetazoa:Y57A10A.18b.1|ensemblmetazoa:Y57A10A.18b.2 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:a5pex6_caeel(display_long)|uniprotkb:Y57A10A.18(orf name)|uniprotkb:pqn-87(gene name)|psi-mi:pqn-87(display_short)|uniprotkb:CELE_Y57A10A.18(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538531|imex:IM-18681-519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) ensemblmetazoa:WBGene00004167(gene)|ensemblmetazoa:Y57A10A.18b.1(transcript)|ensemblmetazoa:Y57A10A.18b.2(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|refseq:NP_001122665.1|wormbase:Y57A10A.18b|uniprotkb:A5PEX6(identity)|wormbase:WBGene00004167(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:U79ecDJtHc4bqHRcr6eBglpyv5k6239 intact-crc:E51A15DD5400B0AF|rigid:AOnYgfmUaG7Rh+utFw1D1DHfi9g false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EG53 uniprotkb:G5EC32 intact:EBI-6536086|ensemblmetazoa:Y50D4C.1a.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:g5eg53_caeel(display_long)|uniprotkb:Y50D4C.1(orf name)|uniprotkb:unc-34(gene name)|psi-mi:unc-34(display_short)|uniprotkb:CELE_Y50D4C.1(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538516|imex:IM-18681-518 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006770(gene)|ensemblmetazoa:Y50D4C.1a.1(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032433"(filopodium tip)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040017"(positive regulation of locomotion)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_503360.4|wormbase:Y50D4C.1a|reactome:R-CEL-446353|uniprotkb:G5EG53(identity)|wormbase:WBGene00006770(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:YztDB2tZk9JFqV25NJfYSwPW5Xo6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:F6D96B271BC4AC9B|rigid:PkapsInunnpbQklXxWJvfH6Dy5M false - sufficient binding region:151-207 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:G5EC32 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538546|imex:IM-18681-520 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 15|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:9B1C85D1618284C9|rigid:LOQMtSD/YX3RvdS5uOLsfiKz9dw false - sufficient binding region:151-207 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q9BIF4 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538561|imex:IM-18681-521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 43|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 intact-crc:AF69B26AF4794FD7|rigid:KqbSdVP4/A6UzHcWUJiHy/PkTiM false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:O01481 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-2316191|ensemblmetazoa:C06A5.8a.1|ensemblmetazoa:C06A5.8a.2 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:o01481_caeel(display_long)|uniprotkb:CELE_C06A5.8(orf name)|uniprotkb:C06A5.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538576|imex:IM-18681-522 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_491737.1|wormbase:C06A5.8a|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|ensemblmetazoa:C06A5.8a.1(transcript)|ensemblmetazoa:C06A5.8a.2(transcript)|ensemblmetazoa:WBGene00015505(gene)|go:"GO:0046872"(metal ion binding)|uniprotkb:O01481(identity)|wormbase:WBGene00015505(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 34|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:Ekx0URCP9yKkM2/26XixY6l2+Oc6239 intact-crc:C371CAD442989272|rigid:GoeZee1wBqkl0qSIGiN8u4VZ8c8 false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:G5EC32 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538591|imex:IM-18681-523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 23|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:6CB2300A7D34857F|rigid:1czevcAqxE6Xv/WTTJk2lwhehRM false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16299 uniprotkb:G5EC32 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538621|imex:IM-18681-525 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 38|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:DBE683596472DF35|rigid:wMrhMqFxdsRSIJMeHvLlM1nscp8 false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:P34397 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-321990|ensemblmetazoa:F10E9.3.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:ylu3_caeel(display_long)|uniprotkb:F10E9.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538606|imex:IM-18681-524 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_498826.2|wormbase:F10E9.3|ensemblmetazoa:F10E9.3.1(transcript)|ensemblmetazoa:WBGene00017355(gene)|interpro:IPR040437|dip:DIP-26529N|uniprotkb:P34397(identity)|wormbase:WBGene00017355(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:rI7gLX2TWTqguT53dk5CTySk7to6239 intact-crc:F8BDA3C462F43D2E|rigid:baA87jvw9Ym4UI7EkCfL3XJkhGw false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q966J6 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-327612|ensemblmetazoa:F41B4.1.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:q966j6_caeel(display_long)|uniprotkb:F41B4.1(orf name)|uniprotkb:CELE_F41B4.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538651|imex:IM-18681-527 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_509148.2|wormbase:F41B4.1|ensemblmetazoa:F41B4.1.1(transcript)|ensemblmetazoa:WBGene00018257(gene)|dip:DIP-26336N|uniprotkb:Q966J6(identity)|wormbase:WBGene00018257(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:daBFAeewQ1vhaxj4tlw0watbWpw6239 intact-crc:3153EF53590B3BCD|rigid:2wlNWz/t1hpwAqnjfkfReSdew4c false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20010 uniprotkb:G5EC32 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538636|imex:IM-18681-526 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N|uniprotkb:Q20010(identity)|wormbase:WBGene00009385(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 26|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:47EEB5A224F3C7D8|rigid:ldHkXo1TxioW8tqp559PqNOJtWQ false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL2 uniprotkb:G5EC32 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538666|imex:IM-18681-528 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:76A3853737DE4FF0|rigid:8jARsY9eT55m75hQY1BX8/U6tWo false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q8I4H7 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-6536499|ensemblmetazoa:K02C4.5.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:q8i4h7_caeel(display_long)|uniprotkb:CELE_K02C4.5(orf name)|uniprotkb:K02C4.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538681|imex:IM-18681-529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) ensemblmetazoa:K02C4.5.1(transcript)|ensemblmetazoa:WBGene00010503(gene)|refseq:NP_495695.2|wormbase:K02C4.5|uniprotkb:Q8I4H7(identity)|wormbase:WBGene00010503(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:/psCM8S6y04pL8WA8ShGIWUwm4Q6239 intact-crc:31B89FE7871A5892|rigid:apcfIRCLwVCBgdNaLyOTWw3UujU false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6BEV5 uniprotkb:G5EC32 intact:EBI-2002318|intact:EBI-2923757|intact:EBI-2924015|ensemblmetazoa:R06F6.12.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:yrmc_caeel(display_long)|uniprotkb:R06F6.12(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538696|imex:IM-18681-530 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022277.1|wormbase:R06F6.12|ensemblmetazoa:R06F6.12.1(transcript)|ensemblmetazoa:WBGene00023418(gene)|uniprotkb:Q6BEV5(identity)|wormbase:WBGene00023418(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:jP7TZCce2muoY78Ruk/qCSELK5M6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:608351811434AA72|rigid:ox5Hh/qn+QF+EB1H9b3Kq8JV/UE false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45812 uniprotkb:G5EC32 intact:EBI-6534925|ensemblmetazoa:T23G11.7b.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:o45812_caeel(display_long)|uniprotkb:CELE_T23G11.7(orf name)|uniprotkb:T23G11.7(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538726|imex:IM-18681-532 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T23G11.7b.1(transcript)|ensemblmetazoa:WBGene00011972(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0005768"(endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0035493"(SNARE complex assembly)|interpro:IPR044538|interpro:IPR023175|refseq:NP_492139.3|wormbase:T23G11.7b|interpro:IPR039431|interpro:IPR041212|uniprotkb:O45812(identity)|wormbase:WBGene00011972(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:us8aG+qHhgBqqdlUEMIme1essQQ6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:FED2E2D22124332F|rigid:gjv3e+MKU0ZJkUyU/aLAGIdq1KI false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:G5EC72 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538711|imex:IM-18681-531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:FFEFB16214C159F8|rigid:r/6eJHXPFJ0INDMk4+iG4XJ2vZI false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q9XWN1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-324865|ensemblmetazoa:Y43F8C.6a.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:q9xwn1_caeel(display_long)|uniprotkb:Y43F8C.6(orf name)|uniprotkb:CELE_Y43F8C.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538741|imex:IM-18681-533 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_001256880.1|wormbase:Y43F8C.6a|ensemblmetazoa:WBGene00012828(gene)|ensemblmetazoa:Y43F8C.6a.1(transcript)|go:"GO:0016589"(NURF complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR037931|dip:DIP-27198N|uniprotkb:Q9XWN1(identity)|wormbase:WBGene00012828(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:BnRBxnWaRRWRCAx+LGlNwRaOcOU6239 intact-crc:3C1DDB96F72BFF5B|rigid:tuUfsCn4JKSzxYBsnc2oD1EIJfg false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:G5EC32 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538756|imex:IM-18681-534 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:F7EA2D6DAB8BB347|rigid:LOQMtSD/YX3RvdS5uOLsfiKz9dw false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XW5 uniprotkb:P24892 intact:EBI-2317194|ensemblmetazoa:Y55B1BR.4.1 intact:EBI-6538775|ensemblmetazoa:MTCE.25.1 psi-mi:q95xw5_caeel(display_long)|uniprotkb:magu-1(gene name)|psi-mi:magu-1(display_short)|uniprotkb:Y55B1BR.4(orf name)|uniprotkb:CELE_Y55B1BR.4(orf name) psi-mi:nu4m_caeel(display_long)|uniprotkb:nduo-4(gene name)|psi-mi:nduo-4(display_short)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym)|uniprotkb:nd4(gene name synonym)|uniprotkb:MTCE.25(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538771|imex:IM-18681-535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497201.1|wormbase:Y55B1BR.4|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013406|interpro:IPR036028|interpro:IPR036034|ensemblmetazoa:WBGene00021914(gene)|ensemblmetazoa:Y55B1BR.4.1(transcript)|uniprotkb:Q95XW5(identity)|wormbase:WBGene00021914(identity) ensemblmetazoa:MTCE.25.1(transcript)|ensemblmetazoa:WBGene00010963(gene)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0048039"(ubiquinone binding)|wormbase:MTCE.25|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|refseq:NP_006960.1|uniprotkb:P24892(identity)|wormbase:WBGene00010963(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:aVqXWeyfbEeIB7tFxhAuoVNRsrM6239 rogid:hUOrQqUVeMcqRAFSLPuYObqtB3I6239 intact-crc:5A4032AA1B7B6C2D|rigid:zrmsdPZhDK7ERVDVMOd4sJCszU4 false sufficient binding region:223-305 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XW5 uniprotkb:Q23050 intact:EBI-2317194|ensemblmetazoa:Y55B1BR.4.1 intact:EBI-326596|ensemblmetazoa:T25F10.6a.1|ensemblmetazoa:T25F10.6a.2 psi-mi:q95xw5_caeel(display_long)|uniprotkb:magu-1(gene name)|psi-mi:magu-1(display_short)|uniprotkb:Y55B1BR.4(orf name)|uniprotkb:CELE_Y55B1BR.4(orf name) psi-mi:q23050_caeel(display_long)|uniprotkb:clik-1(gene name)|psi-mi:clik-1(display_short)|uniprotkb:CELE_T25F10.6(orf name)|uniprotkb:T25F10.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538788|imex:IM-18681-536 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497201.1|wormbase:Y55B1BR.4|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013406|interpro:IPR036028|interpro:IPR036034|ensemblmetazoa:WBGene00021914(gene)|ensemblmetazoa:Y55B1BR.4.1(transcript)|uniprotkb:Q95XW5(identity)|wormbase:WBGene00021914(identity) refseq:NP_001024158.1|wormbase:T25F10.6a|ensemblmetazoa:T25F10.6a.1(transcript)|ensemblmetazoa:T25F10.6a.2(transcript)|ensemblmetazoa:WBGene00020808(gene)|interpro:IPR000557(Calponin repeat)|dip:DIP-27445N|reactome:R-CEL-114608|uniprotkb:Q23050(identity)|wormbase:WBGene00020808(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:aVqXWeyfbEeIB7tFxhAuoVNRsrM6239 rogid:CJGK9iuGtzmGkvXphcPiglOyZdw6239 intact-crc:73BB89D6F8202DFE|rigid:OVr+5svbMd60bMbrEa05pmFliXU false sufficient binding region:223-305 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:O62011 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6456084|ensemblmetazoa:B0379.3a.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:o62011_caeel(display_long)|uniprotkb:B0379.3(orf name)|uniprotkb:mut-16(gene name)|psi-mi:mut-16(display_short)|uniprotkb:CELE_B0379.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538803|imex:IM-18681-537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:B0379.3a.1(transcript)|ensemblmetazoa:WBGene00003508(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016246"(RNA interference)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:1990633"(mutator focus)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_492660.3|wormbase:B0379.3a|uniprotkb:O62011(identity)|wormbase:WBGene00003508(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:gMuLdz+fFz3VGJe/rR1zhKWvqIQ6239 intact-crc:C082C244C01F4821|rigid:OWNUoYxHfm+T8xqtU8OOts9upjA false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:O45233 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-330100|ensemblmetazoa:C01G12.1.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:o45233_caeel(display_long)|uniprotkb:C01G12.1(orf name)|uniprotkb:madf-5(gene name)|psi-mi:madf-5(display_short)|uniprotkb:CELE_C01G12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538820|imex:IM-18681-538 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_497028.1|wormbase:C01G12.1|dip:DIP-27356N|ensemblmetazoa:C01G12.1.1(transcript)|ensemblmetazoa:WBGene00007242(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR004210(BESS motif)|interpro:IPR006578(MADF)|interpro:IPR039353|uniprotkb:O45233(identity)|wormbase:WBGene00007242(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:Jl0eRKrcRF0Blr+KcjsW5mWaBaU6239 intact-crc:432BA8688E953DCA|rigid:j5glj4KIzQ+4oXe5NI2Xy0wh/os false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39055 uniprotkb:G5EE56 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538835|imex:IM-18681-539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 42|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:376D3A2EB72ADD13|rigid:owBNvXGW7fWrc3Hl6/j2DOoy/PA false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:O16310 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6538854|ensemblmetazoa:C05C8.4.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:o16310_caeel(display_long)|uniprotkb:C05C8.4(orf name)|uniprotkb:gei-6(gene name)|psi-mi:gei-6(display_short)|uniprotkb:CELE_C05C8.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538850|imex:IM-18681-540 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:C05C8.4.1(transcript)|ensemblmetazoa:WBGene00001563(gene)|refseq:NP_504836.1|wormbase:C05C8.4|uniprotkb:O16310(identity)|wormbase:WBGene00001563(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:+dMc7qoYdqdALbP6h4C1DrF/Dq06239 intact-crc:F5C2337C2426E51A|rigid:AECymBMlkulp+SW6x694cM2U+qQ false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17865 uniprotkb:G5EE56 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538882|imex:IM-18681-542 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:BC2F66392F7D2CBB|rigid:VzpDNuiFHTXy4FML+O9zL/t38s0 false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q09442 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538867|imex:IM-18681-541 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 114|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 intact-crc:AD63787F5021D0BD|rigid:iYkI6l2JDY64geSkGCjk4kU30eI false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18239 uniprotkb:G5EE56 intact:EBI-314248|ensemblmetazoa:C27A2.6.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q18239_caeel(display_long)|uniprotkb:dsh-2(gene name)|psi-mi:dsh-2(display_short)|uniprotkb:CELE_C27A2.6(orf name)|uniprotkb:C27A2.6(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538897|imex:IM-18681-543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C27A2.6|reactome:R-CEL-201688|reactome:R-CEL-4086400|reactome:R-CEL-4641258|ensemblmetazoa:C27A2.6.1(transcript)|ensemblmetazoa:WBGene00001102(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060069"(Wnt signaling pathway, regulating spindle positioning)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070986"(left/right axis specification)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|reactome:R-CEL-5663220|refseq:NP_494937.4|dip:DIP-24740N|reactome:R-CEL-5099900|reactome:R-CEL-2028269|reactome:R-CEL-4641262|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:Q18239(identity)|wormbase:WBGene00001102(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:yDb25aMPWu/bsUAWs6+ZIhpWpOU6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:5003E797E3F29882|rigid:0asudtsACqvIuQs1s5M/CSz1PJw false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q18605 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-331810|ensemblmetazoa:C44B9.4.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q18605_caeel(display_long)|uniprotkb:athp-1(gene name)|psi-mi:athp-1(display_short)|uniprotkb:CELE_C44B9.4(orf name)|uniprotkb:C44B9.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538912|imex:IM-18681-544 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_499397.2|wormbase:C44B9.4|dip:DIP-27259N|ensemblmetazoa:C44B9.4.1(transcript)|ensemblmetazoa:WBGene00008081(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR042163|uniprotkb:Q18605(identity)|wormbase:WBGene00008081(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:H5ZuRoDCv1AIMpTM9EehO/NyVd86239 intact-crc:0988FB9B33FB3198|rigid:LJezVsR+jdRlsW6ZXLVgQIV7XdQ false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:G5EFZ9 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6538931|ensemblmetazoa:C46H11.11a.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:g5efz9_caeel(display_long)|uniprotkb:C46H11.11(orf name)|uniprotkb:fhod-1(gene name)|psi-mi:fhod-1(display_short)|uniprotkb:CELE_C46H11.11(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538927|imex:IM-18681-545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) wormbase:C46H11.11a|ensemblmetazoa:C46H11.11a.1(transcript)|ensemblmetazoa:WBGene00016735(gene)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_491513.2|interpro:IPR042201|interpro:IPR041387|uniprotkb:G5EFZ9(identity)|wormbase:WBGene00016735(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:igG/LeOkDoPfWLC/32q7EkQRdUA6239 intact-crc:B412EB7A1DBA631F|rigid:v5AUM9XBJcB25CS+aSpWluH7bwU false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QQ9 uniprotkb:G5EE56 intact:EBI-2317344|ensemblmetazoa:C49H3.6a.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q95qq9_caeel(display_long)|uniprotkb:C49H3.6(orf name)|uniprotkb:CELE_C49H3.6(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538944|imex:IM-18681-546 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501316.2|wormbase:C49H3.6a|interpro:IPR019131|ensemblmetazoa:C49H3.6a.1(transcript)|ensemblmetazoa:WBGene00016792(gene)|go:"GO:0005737"(cytoplasm)|uniprotkb:Q95QQ9(identity)|wormbase:WBGene00016792(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 47|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eHT6KUXkocreuSpbjuHpYT+s+tQ6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:500EF66173365D40|rigid:q4cGkthvudTrs+BGnpC7c66AaI4 false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:O01864 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6538963|ensemblmetazoa:D1007.7.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:o01864_caeel(display_long)|uniprotkb:D1007.7(orf name)|uniprotkb:nrd-1(gene name)|psi-mi:nrd-1(display_short)|uniprotkb:CELE_D1007.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538959|imex:IM-18681-547 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:D1007.7.1(transcript)|ensemblmetazoa:WBGene00017004(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|refseq:NP_491403.1|wormbase:D1007.7|interpro:IPR035979|uniprotkb:O01864(identity)|wormbase:WBGene00017004(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:ePL0xkrYQaWC4+Bf0/FZaOfPmRM6239 intact-crc:A76370C59C52BF94|rigid:uaqfrHchn++tVWjKh+0DkT50Sh8 false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9TYS1 uniprotkb:G5EE56 intact:EBI-321736|ensemblmetazoa:D1037.1.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q9tys1_caeel(display_long)|uniprotkb:D1037.1(orf name)|uniprotkb:CELE_D1037.1(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538976|imex:IM-18681-548 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491200.1|wormbase:D1037.1|ensemblmetazoa:D1037.1.1(transcript)|ensemblmetazoa:WBGene00017025(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR000467(D111/G-patch)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032922|dip:DIP-25428N|uniprotkb:Q9TYS1(identity)|wormbase:WBGene00017025(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BYcktBm9BFEexLqJMazfrDsQoMM6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:4D60AAC1D31A757C|rigid:/zIiJkPWUxlss5dT8YURzap1OkQ false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P46562 uniprotkb:G5EE56 intact:EBI-320383|ensemblmetazoa:F01F1.6.1|ensemblmetazoa:F01F1.6.2 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:al7a1_caeel(display_long)|uniprotkb:F01F1.6(orf name)|uniprotkb:alh-9(gene name)|psi-mi:alh-9(display_short)|uniprotkb:ALH-9(gene name synonym) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6538991|imex:IM-18681-549 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498263.2|wormbase:F01F1.6|reactome:R-CEL-6798163|ensemblmetazoa:F01F1.6.1(transcript)|ensemblmetazoa:F01F1.6.2(transcript)|ensemblmetazoa:WBGene00000115(gene)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|interpro:IPR044638|reactome:R-CEL-71064|dip:DIP-25437N|uniprotkb:P46562(identity)|wormbase:WBGene00000115(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Y3JXgD6adGR1ycckEpvT2oSCvKM6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:08354DE0FDA37316|rigid:3CPkjCCEGE3UehQWtvNK7VEGvug false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q7JP65 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6532045|ensemblmetazoa:F10D7.5b.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q7jp65_caeel(display_long)|uniprotkb:CELE_F10D7.5(orf name)|uniprotkb:F10D7.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539006|imex:IM-18681-550 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:F10D7.5b.1(transcript)|ensemblmetazoa:WBGene00017342(gene)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006573(NEUZ)|refseq:NP_510817.3|wormbase:F10D7.5b|interpro:IPR037962|interpro:IPR043136|uniprotkb:Q7JP65(identity)|wormbase:WBGene00017342(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:dmeTGxA1egh7S0o5roMacNRvJzA6239 intact-crc:C7B1BCD64F163CE7|rigid:chfK9pIATjOOGcxefUzMSgV3GO4 false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:A9D4E4 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6536798|ensemblmetazoa:F13H6.1b.1|ensemblmetazoa:F13H6.1b.2 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:a9d4e4_caeel(display_long)|uniprotkb:bcl-11(gene name)|psi-mi:bcl-11(display_short)|uniprotkb:CELE_F13H6.1(orf name)|uniprotkb:F13H6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539021|imex:IM-18681-551 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:F13H6.1b.1(transcript)|ensemblmetazoa:F13H6.1b.2(transcript)|ensemblmetazoa:WBGene00017430(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001122913.1|wormbase:F13H6.1b|interpro:IPR036236|uniprotkb:A9D4E4(identity)|wormbase:WBGene00017430(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:JvzwXvK36+TbPNFYnrUn/O65V9U6239 intact-crc:65F486BFD23A58F0|rigid:guuUozvv9AJELWSPiAeHiq7u3ac false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED57 uniprotkb:G5EE56 intact:EBI-327853|ensemblmetazoa:F22E12.1.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:g5ed57_caeel(display_long)|uniprotkb:F22E12.1(orf name)|uniprotkb:CELE_F22E12.1(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539036|imex:IM-18681-552 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O45916(uniprot-removed-ac)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR020901|refseq:NP_505684.2|wormbase:F22E12.1|ensemblmetazoa:F22E12.1.1(transcript)|ensemblmetazoa:WBGene00009058(gene)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036880|uniprotkb:G5ED57(identity)|wormbase:WBGene00009058(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:+Rdyx7pnykvpAExFI2L56AHfbIc6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:73AD56AD4D2DB275|rigid:plttj5WCeZW+lDssNGKt6lNuWdc false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:B3GWA0 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6534207|ensemblmetazoa:F25B5.7c.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:b3gwa0_caeel(display_long)|uniprotkb:nono-1(gene name)|psi-mi:nono-1(display_short)|uniprotkb:CELE_F25B5.7(orf name)|uniprotkb:F25B5.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539051|imex:IM-18681-553 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:F25B5.7c.1(transcript)|ensemblmetazoa:WBGene00017778(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR012975(NOPS)|refseq:NP_498296.3|wormbase:F25B5.7c|uniprotkb:B3GWA0(identity)|wormbase:WBGene00017778(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:lWJ7KO5EiJ5HtKHW+fGsAOn5RhU6239 intact-crc:5FF5ACEA397B7020|rigid:L3vdVf/8yybn8jQynRCosJDjsd8 false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19905 uniprotkb:G5EE56 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539081|imex:IM-18681-555 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N|uniprotkb:Q19905(identity)|wormbase:WBGene00005022(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:D1C9E62B74C6B7D0|rigid:8dv7AW4VKqiJ6BeI5PwGEEgSw1U false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED20 uniprotkb:G5EE56 intact:EBI-319647|ensemblmetazoa:F26G5.9.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:g5ed20_caeel(display_long)|uniprotkb:tam-1(gene name)|psi-mi:tam-1(display_short)|uniprotkb:CELE_F26G5.9(orf name)|uniprotkb:F26G5.9(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539066|imex:IM-18681-554 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O16936(uniprot-removed-ac)|interpro:IPR027370|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR017907|refseq:NP_504335.1|ensemblmetazoa:F26G5.9.1(transcript)|ensemblmetazoa:WBGene00006523(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000785"(chromatin)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0043073"(germ cell nucleus)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|wormbase:F26G5.9|reactome:R-CEL-3108214|reactome:R-CEL-8934593|reactome:R-CEL-8948747|uniprotkb:G5ED20(identity)|wormbase:WBGene00006523(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BZmiHrHEQepSGkEZzAc0jHJXnNE6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:6D68122BD8BD7121|rigid:5Xq93dCltRJuk6a0BKAUs3bcROw false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:E3W743 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539096|imex:IM-18681-556 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 21|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 intact-crc:49361D631A39EE6E|rigid:OhVG1trWo5OmNHxESLWt8PKYd0M false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:O16299 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539111|imex:IM-18681-557 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 intact-crc:311E45BCEDD101D5|rigid:LOmwaIbKLiugw9gSew6WxuBDwfw false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:A5JYT7 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6536255|ensemblmetazoa:F32D8.7b.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:a5jyt7_caeel(display_long)|uniprotkb:CELE_F32D8.7(orf name)|uniprotkb:F32D8.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539126|imex:IM-18681-558 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:F32D8.7b.1(transcript)|ensemblmetazoa:WBGene00009331(gene)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|refseq:NP_001122937.1|wormbase:F32D8.7b|interpro:IPR036880|uniprotkb:A5JYT7(identity)|wormbase:WBGene00009331(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:PQPBy2+5kZase8AL+5EcdwnU22k6239 intact-crc:BCD9FBF2F6E9E186|rigid:noqQj/WJU1FY7h2VcPc9vFoJozA false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q95YA9 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6536858|ensemblmetazoa:F41G4.2a.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q95ya9_caeel(display_long)|uniprotkb:F41G4.2(orf name)|uniprotkb:cas-1(gene name)|psi-mi:cas-1(display_short)|uniprotkb:CELE_F41G4.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539141|imex:IM-18681-559 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) interpro:IPR028417|reactome:R-CEL-6798695|ensemblmetazoa:F41G4.2a.1(transcript)|ensemblmetazoa:WBGene00000294(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR017901|wormbase:F41G4.2a|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR036222|interpro:IPR036223|interpro:IPR028419|refseq:NP_510714.1|uniprotkb:Q95YA9(identity)|wormbase:WBGene00000294(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:Wtu62Erja5FAbcy4JVr/DUWQf0w6239 intact-crc:4B1E6DD490234608|rigid:P/I7YHG5brCYSl262NGM5nxM+N0 false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:G5ECW9 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-315316|ensemblmetazoa:F46F6.1a.1|ensemblmetazoa:F46F6.1a.2 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:g5ecw9_caeel(display_long)|uniprotkb:rme-4(gene name)|psi-mi:rme-4(display_short)|uniprotkb:F46F6.1(orf name)|uniprotkb:CELE_F46F6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539171|imex:IM-18681-561 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) uniprotkb:Q20473(uniprot-removed-ac)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|refseq:NP_509739.1|wormbase:F46F6.1a|mint:G5ECW9|ensemblmetazoa:F46F6.1a.1(transcript)|ensemblmetazoa:F46F6.1a.2(transcript)|ensemblmetazoa:WBGene00004375(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR043153|interpro:IPR040032|interpro:IPR037516|uniprotkb:G5ECW9(identity)|wormbase:WBGene00004375(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 29|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:3FE5ecvvghPRxJTDrlb8Ij9Vzx46239 intact-crc:1DD9B44C48DC211F|rigid:DH74LACGOr+yW66Wl3rPTlSS9Qg false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20330 uniprotkb:G5EE56 intact:EBI-322042|ensemblmetazoa:F42C5.10.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q20330_caeel(display_long)|uniprotkb:ifo-1(gene name)|psi-mi:ifo-1(display_short)|uniprotkb:ttm-4(gene name synonym)|uniprotkb:CELE_F42C5.10(orf name)|uniprotkb:F42C5.10(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539156|imex:IM-18681-560 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501170.1|wormbase:F42C5.10|ensemblmetazoa:F42C5.10.1(transcript)|ensemblmetazoa:WBGene00018350(gene)|dip:DIP-27375N|uniprotkb:Q20330(identity)|wormbase:WBGene00018350(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G/TdIwuOTGQMqaW/I1aJ4GvrtlU6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:B4A73BBEA0E39B78|rigid:64KEKUyCkNaXdq3pezyfDLubZ8E false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q3Y407 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-2317687|uniprotkb:G4SJ35|ensemblmetazoa:F46H5.6.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q3y407_caeel(display_long)|uniprotkb:grd-7(gene name)|psi-mi:grd-7(display_short)|uniprotkb:CELE_F46H5.6(orf name)|uniprotkb:F46H5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539186|imex:IM-18681-562 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) interpro:IPR007284(Ground-like region)|wormbase:F46H5.6|interpro:IPR003882(Pistil-specific extensin-like protein)|ensemblmetazoa:F46H5.6.1(transcript)|ensemblmetazoa:WBGene00001696(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007154"(cell communication)|uniprotkb:Q3Y407(identity)|wormbase:WBGene00001696(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/01/23 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:77+Ww780xL2+LUmBj5htUR6eidA6239 intact-crc:96F69C5A852F0661|rigid:OVmAzd+hgo75fAI9Rx6qBj+IRTI false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65ZB4 uniprotkb:G5EE56 intact:EBI-6532971|ensemblmetazoa:F54D5.15b.1|ensemblmetazoa:F54D5.15b.2 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q65zb4_caeel(display_long)|uniprotkb:CELE_F54D5.15(orf name)|uniprotkb:F54D5.15(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539201|imex:IM-18681-563 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F54D5.15b.1(transcript)|ensemblmetazoa:F54D5.15b.2(transcript)|ensemblmetazoa:WBGene00010057(gene)|refseq:NP_001022200.1|wormbase:F54D5.15b|uniprotkb:Q65ZB4(identity)|wormbase:WBGene00010057(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:HNrF4GLN9SQWi6CrHUP8geHepb06239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:E5937786AE0E7EC7|rigid:h0Kd0RHmhdIEoud0MYqLgF0hawM false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20798 uniprotkb:G5EE56 intact:EBI-314927|ensemblmetazoa:F55A11.3.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:hrd1_caeel(display_long)|uniprotkb:F55A11.3(orf name)|uniprotkb:sel-11(gene name)|psi-mi:sel-11(display_short)|uniprotkb:hrd-1(gene name synonym)|uniprotkb:Suppressor/enhancer of lin-12(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase hrd-1(gene name synonym) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539216|imex:IM-18681-564 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505969.1|wormbase:F55A11.3|ensemblmetazoa:F55A11.3.1(transcript)|ensemblmetazoa:WBGene00004768(gene)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|dip:DIP-26690N|reactome:R-CEL-5358346|uniprotkb:Q20798(identity)|wormbase:WBGene00010076(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:TSaVPoe9ktpPQgjKmybrpfJYD5o6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:8763A0917045337A|rigid:x2KZyQWe5sXuqnT949SB5S8P/Ss false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76337 uniprotkb:G5EE56 intact:EBI-6532169|ensemblmetazoa:F56D2.7.1|uniprotkb:O01421 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:ced6_caeel(display_long)|uniprotkb:ced-6(gene name)|psi-mi:ced-6(display_short)|uniprotkb:Candidate adapter protein ced-6(gene name synonym)|uniprotkb:F56D2.7(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539231|imex:IM-18681-565 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F56D2.7.1(transcript)|ensemblmetazoa:WBGene00000420(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012501"(programmed cell death)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0070986"(left/right axis specification)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|go:"GO:1904747"(positive regulation of apoptotic process involved in development)|go:"GO:0045335"(phagocytic vesicle)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_498203.2|wormbase:F56D2.7|uniprotkb:O76337(identity)|wormbase:WBGene00000420(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 78|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VjlyH911QZCg4QZbyWiJu1i01cg6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:D09D9359350E3E0E|rigid:VSVawg5Mw8B2k/E1nWXtvOkvICE false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:O01900 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539246|imex:IM-18681-566 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 48|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 intact-crc:5FAF52182E9D8CA0|rigid:pmBBl5Zc2s0oPixs9H8Ee0ZivCY false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6539265 uniprotkb:G5EE56 - intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q8mxf4_caeel(display_short)|psi-mi:EBI-6539265(display_long)|uniprotkb:CELE_H28G03.2(orf name)|uniprotkb:H28G03.2(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539261|imex:IM-18681-567 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8MXF4(uniprot-removed-ac)|uniprotkb:Q8MXF4(identity)|wormbase:WBGene00019250(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:/K3lYqbEluXNvbVt9sMLGrKLw0M6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:DA57765DF0D00B39|rigid:s6g9OnskHfqPH5lV6QWYLVwugKA false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:G5ECL2 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539278|imex:IM-18681-568 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 intact-crc:056426C75C815E47|rigid:VdN4rIqG/IR8ImZQUwSgS+szDvs false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E7EM33 uniprotkb:G5EE56 intact:EBI-6535096|ensemblmetazoa:K11E8.1q.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:e7em33_caeel(display_long)|uniprotkb:K11E8.1(orf name)|uniprotkb:unc-43(gene name)|psi-mi:unc-43(display_short)|uniprotkb:CELE_K11E8.1(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539308|imex:IM-18681-570 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K11E8.1q.1(transcript)|ensemblmetazoa:WBGene00006779(gene)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|interpro:IPR032710|refseq:NP_001255483.1|wormbase:K11E8.1q|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|uniprotkb:E7EM33(identity)|wormbase:WBGene00006779(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:wJ7Mv8XBGds/21oTfrakhpmcoUM6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:897788A9E5AF5F24|rigid:w3I0a4zGDVMaqfQ1DZ2RygYoPv0 false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8I4H7 uniprotkb:G5EE56 intact:EBI-6536499|ensemblmetazoa:K02C4.5.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q8i4h7_caeel(display_long)|uniprotkb:CELE_K02C4.5(orf name)|uniprotkb:K02C4.5(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539293|imex:IM-18681-569 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K02C4.5.1(transcript)|ensemblmetazoa:WBGene00010503(gene)|refseq:NP_495695.2|wormbase:K02C4.5|uniprotkb:Q8I4H7(identity)|wormbase:WBGene00010503(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 59|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:/psCM8S6y04pL8WA8ShGIWUwm4Q6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:1BF42F3EB4C1E388|rigid:WFsy2s7dODPwXJ0zaqf91eP//Ig false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:U4PCM1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6539327|ensemblmetazoa:R06A4.9a.1|uniprotkb:A0A5S9MNP8|uniprotkb:U4PN22 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:wdr33_caeel(display_long)|uniprotkb:pfs-2(gene name)|psi-mi:pfs-2(display_short)|uniprotkb:R06A4.9(orf name)|uniprotkb:Polyadenylation factor subunit homolog 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539323|imex:IM-18681-571 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:R06A4.9a.1(transcript)|ensemblmetazoa:WBGene00011051(gene)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016607"(nuclear speck)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-73856|reactome:R-CEL-77595|refseq:NP_001293597.1|refseq:NP_001293598.1|wormbase:R06A4.9a|wormbase:R06A4.9b|wormbase:R06A4.9c|uniprotkb:Q9NAN8(uniprot-removed-ac)|uniprotkb:Q9NAN8(identity)|wormbase:WBGene00011051(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:jE6mq6J15sO/9bnrnpbAwVjU8f46239 intact-crc:29E9A9093118F441|rigid:zEkCs5RjcVPFSNik/Tk9kwYKV6M false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q21920 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-2917287|ensemblmetazoa:R11A8.7a.1|uniprotkb:A3RMT6|uniprotkb:Q9TW88|uniprotkb:Q21927|uniprotkb:A3RMT7|uniprotkb:D3YT52|uniprotkb:L8E837|uniprotkb:L8E927|uniprotkb:L8EC41 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:ankhm_caeel(display_long)|uniprotkb:mask-1(gene name)|psi-mi:mask-1(display_short)|uniprotkb:Multiple ankyrin repeats single KH domain homolog(gene name synonym)|uniprotkb:R11A8.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539340|imex:IM-18681-572 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:R11A8.7a.1(transcript)|ensemblmetazoa:WBGene00011240(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|refseq:NP_001122794.1|refseq:NP_001122795.1|wormbase:R11A8.7a|wormbase:R11A8.7b|wormbase:R11A8.7c|wormbase:R11A8.7d|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|refseq:NP_001255486.1|refseq:NP_001263772.1|refseq:NP_001263773.1|refseq:NP_001263774.1|refseq:NP_501915.2|refseq:NP_501916.2|wormbase:R11A8.7e|wormbase:R11A8.7f|wormbase:R11A8.7g|wormbase:R11A8.7h|interpro:IPR036612|interpro:IPR036770|uniprotkb:Q21920(identity)|wormbase:WBGene00011240(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:zKHGpUoL9/xlqeJg8JDUYwccRtw6239 intact-crc:2CD475F7F92FBD5E|rigid:2tppgTuoU9Btt4Tmf8fyp/H5alI false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09345 uniprotkb:G5EE56 intact:EBI-2006279|ensemblmetazoa:R144.2a.1|ensemblmetazoa:R144.2a.2 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:pcf11_caeel(display_long)|uniprotkb:R144.2(orf name)|uniprotkb:pcf-11(gene name)|psi-mi:pcf-11(display_short) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539355|imex:IM-18681-573 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498068.1|wormbase:R144.2a|interpro:IPR008942(ENTH/VHS)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|reactome:R-CEL-6807505|reactome:R-CEL-73856|ensemblmetazoa:R144.2a.1(transcript)|ensemblmetazoa:R144.2a.2(transcript)|ensemblmetazoa:WBGene00020092(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|uniprotkb:Q09345(identity)|wormbase:WBGene00020092(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:XTyRR+k9dN5uoxwUXnAuM34SSUA6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:65AED300B639F80C|rigid:XAxwhzM9gyR1IHSQAXaNfIr1BrY false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:G5EE56 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539385|imex:IM-18681-575 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 29|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:C84F13E6834B6ADA|rigid:n5o/LaiNfqAWzpbC/lYgF5veUTE false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q8ITY8 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-327939|intact:EBI-2923970|ensemblmetazoa:R148.3b.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q8ity8_caeel(display_long)|uniprotkb:R148.3(orf name)|uniprotkb:CELE_R148.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539370|imex:IM-18681-574 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_871687.1|wormbase:R148.3b|ensemblmetazoa:R148.3b.1(transcript)|ensemblmetazoa:WBGene00020102(gene)|uniprotkb:Q8ITY8(identity)|wormbase:WBGene00020102(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:ZgYiu6NLo9PJibS31GUMNYbLseo6239 intact-crc:B226F6E05A0C5581|rigid:S6ixto6OtZzC4kCliCzLqX5K7Xw false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:G5EF96 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6539400|ensemblmetazoa:T19B4.7.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:unc40_caeel(display_long)|uniprotkb:Uncoordinated protein 40(gene name synonym)|uniprotkb:T19B4.7(orf name)|uniprotkb:unc-40(gene name)|psi-mi:unc-40(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539402|imex:IM-18681-576 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:T19B4.7.1(transcript)|ensemblmetazoa:WBGene00006776(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0016020"(membrane)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031253"(cell projection membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0035545"(determination of left/right asymmetry in nervous system)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042661"(regulation of mesodermal cell fate specification)|go:"GO:0043235"(receptor complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061643"(chemorepulsion of axon)|go:"GO:0097374"(sensory neuron axon guidance)|go:"GO:0097402"(neuroblast migration)|go:"GO:0097628"(distal tip cell migration)|go:"GO:1901048"(transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth)|go:"GO:1905490"(negative regulation of sensory neuron axon guidance)|go:"GO:1905812"(regulation of motor neuron axon guidance)|go:"GO:1905815"(regulation of dorsal/ventral axon guidance)|reactome:R-CEL-418889|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_491664.1|wormbase:T19B4.7|reactome:R-CEL-418885|reactome:R-CEL-373752|interpro:IPR036116|interpro:IPR036179|uniprotkb:G5EF96(identity)|wormbase:WBGene00006776(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:1sBhPuEB/k8coiKriwx8Q+aSrsk6239 intact-crc:F248187EAEA08584|rigid:P4bSi2x0PD7AbqVkkUwNSU+gGQs false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XUK2 uniprotkb:G5EE56 intact:EBI-322774|ensemblmetazoa:W07G1.3.1|ensemblmetazoa:W07G1.3.2 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:zip3_caeel(display_long)|uniprotkb:zip-3(gene name)|psi-mi:zip-3(display_short)|uniprotkb:BZIP transcription factor family zip-3(gene name synonym)|uniprotkb:W07G1.3(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539432|imex:IM-18681-578 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496919.2|wormbase:W07G1.3|ensemblmetazoa:W07G1.3.1(transcript)|ensemblmetazoa:W07G1.3.2(transcript)|ensemblmetazoa:WBGene00012330(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|dip:DIP-26962N|uniprotkb:Q9XUK2(identity)|wormbase:WBGene00012330(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:kB4fbQderNIpDQpNBeAeRjhox3k6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:B354D1247B6385DC|rigid:CAij5IPIFJveYaGMosb+GeH1iZQ false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91820 uniprotkb:G5EE56 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539417|imex:IM-18681-577 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N|uniprotkb:P91820(identity)|wormbase:WBGene00003083(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 25|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:5697470AB9D59977|rigid:ibwLp5MwVkmits99z3W2IUbNMpc false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q9U304 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-329038|ensemblmetazoa:Y106G6D.7.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q9u304_caeel(display_long)|uniprotkb:rbm-12(gene name)|psi-mi:rbm-12(display_short)|uniprotkb:CELE_Y106G6D.7(orf name)|uniprotkb:Y106G6D.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539447|imex:IM-18681-579 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_492671.1|wormbase:Y106G6D.7|dip:DIP-26480N|ensemblmetazoa:WBGene00013703(gene)|ensemblmetazoa:Y106G6D.7.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-CEL-72163|uniprotkb:Q9U304(identity)|wormbase:WBGene00013703(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 28|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:/8MJkmHgCyjvgK0ZmDnklHVfJrw6239 intact-crc:E707E342F06DBDF7|rigid:yfx5YOY8O06oopFVolri+oG8fc0 false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6534333 uniprotkb:G5EE56 - intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q965y4_caeel(display_short)|psi-mi:EBI-6534333(display_long)|uniprotkb:Y110A2AM.1(gene name)|psi-mi:Y110A2AM.1(display_short)|uniprotkb:CELE_Y110A2AM.1(orf name)|uniprotkb:Y110A2AM.1(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539462|imex:IM-18681-580 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q965Y4(uniprot-removed-ac)|uniprotkb:Q965Y4(identity)|wormbase:WBGene00022449(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zqy/LYo1vjSCTC0G4hp+sZ4vti06239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:8F387D15795B3F74|rigid:sW9G3UMpqdKSpzeyBHVODoAxs2g false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q8I4E2 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-4325777|uniprotkb:D3NQ98|uniprotkb:J7SA60|uniprotkb:Q8I4E1|uniprotkb:Q9XXG2|uniprotkb:Q9XXG3|ensemblmetazoa:Y37A1B.2c.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:lst4_caeel(display_long)|uniprotkb:lst-4(gene name)|psi-mi:lst-4(display_short)|uniprotkb:Lateral signaling target protein 4(gene name synonym)|uniprotkb:Y37A1B.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539477|imex:IM-18681-581 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) interpro:IPR036871|interpro:IPR027267|interpro:IPR036028|wormbase:Y37A1B.2d|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|reactome:R-CEL-8856828|refseq:NP_502693.2|wormbase:Y37A1B.2a|wormbase:Y37A1B.2b|wormbase:Y37A1B.2c|wormbase:Y37A1B.2e|wormbase:Y37A1B.2f|refseq:NP_001255779.1|refseq:NP_001263811.1|refseq:NP_502694.1|refseq:NP_502695.2|refseq:NP_872090.1|reactome:R-CEL-432722|go:"GO:0032009"(early phagosome)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045335"(phagocytic vesicle)|ensemblmetazoa:WBGene00003086(gene)|ensemblmetazoa:Y37A1B.2c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0090389"(phagosome-lysosome fusion involved in apoptotic cell clearance)|go:"GO:0097194"(execution phase of apoptosis) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:NqGhrxQdIIT2DDOgu+/swsZFniQ6239 intact-crc:7D362F57AC3D85D2|rigid:TSqX75mdhoGu+WEuVj09zia4QDo false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q9XWN1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-324865|ensemblmetazoa:Y43F8C.6a.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q9xwn1_caeel(display_long)|uniprotkb:Y43F8C.6(orf name)|uniprotkb:CELE_Y43F8C.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539492|imex:IM-18681-582 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_001256880.1|wormbase:Y43F8C.6a|ensemblmetazoa:WBGene00012828(gene)|ensemblmetazoa:Y43F8C.6a.1(transcript)|go:"GO:0016589"(NURF complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR037931|dip:DIP-27198N|uniprotkb:Q9XWN1(identity)|wormbase:WBGene00012828(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:BnRBxnWaRRWRCAx+LGlNwRaOcOU6239 intact-crc:CA8FEB49E6629FF6|rigid:GEKu6UOsvYSti+t7Vwh2lH831bI false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:G5EE56 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539507|imex:IM-18681-583 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:8FC202568DDEE982|rigid:HAIoScxYbCo1P8fIFEv7HaiLryo false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q9U290 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6535173|ensemblmetazoa:Y48C3A.12.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q9u290_caeel(display_long)|uniprotkb:CELE_Y48C3A.12(orf name)|uniprotkb:Y48C3A.12(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539522|imex:IM-18681-584 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) reactome:R-CEL-2672351|ensemblmetazoa:WBGene00012994(gene)|ensemblmetazoa:Y48C3A.12.1(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000580(TSC-22 / Dip / Bun)|refseq:NP_496820.3|wormbase:Y48C3A.12|uniprotkb:Q9U290(identity)|wormbase:WBGene00012994(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 67|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:j5mfkqYUtbsxlXm88eVGbYZKfe46239 intact-crc:567FEF5AFC642AFC|rigid:HxWu33RiC23Hrzh9OwTz7LXiM/o false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BL72 uniprotkb:G5EE56 intact:EBI-6539537|ensemblmetazoa:Y48G9A.4.1|ensemblmetazoa:Y48G9A.4.2 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q9bl72_caeel(display_long)|uniprotkb:Y48G9A.4(orf name)|uniprotkb:frl-1(gene name)|psi-mi:frl-1(display_short)|uniprotkb:CELE_Y48G9A.4(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539539|imex:IM-18681-585 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043592|ensemblmetazoa:WBGene00021698(gene)|ensemblmetazoa:Y48G9A.4.1(transcript)|ensemblmetazoa:Y48G9A.4.2(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR011989(Armadillo-like helical)|reactome:R-CEL-8980692|reactome:R-CEL-9013149|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_497505.3|wormbase:Y48G9A.4|reactome:R-CEL-5663220|interpro:IPR042201|uniprotkb:Q9BL72(identity)|wormbase:WBGene00021698(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 21|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:sBa5W0OQVobjADA/+GubhvAhRqo6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:DF3E55FDDD769556|rigid:jIJyzx3meWXiE5ph6HZ5/SRvryc false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EG53 uniprotkb:G5EE56 intact:EBI-6536086|ensemblmetazoa:Y50D4C.1a.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:g5eg53_caeel(display_long)|uniprotkb:Y50D4C.1(orf name)|uniprotkb:unc-34(gene name)|psi-mi:unc-34(display_short)|uniprotkb:CELE_Y50D4C.1(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539554|imex:IM-18681-586 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006770(gene)|ensemblmetazoa:Y50D4C.1a.1(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032433"(filopodium tip)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040017"(positive regulation of locomotion)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_503360.4|wormbase:Y50D4C.1a|reactome:R-CEL-446353|uniprotkb:G5EG53(identity)|wormbase:WBGene00006770(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|wormbase:WBGene00005077(identity)|uniprotkb:G5EE56(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 18|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:YztDB2tZk9JFqV25NJfYSwPW5Xo6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:F96BC50F0B876618|rigid:lMIWCZVzt92RK3Qk1DZfe3ADbZo false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A5PEX6 uniprotkb:G5EE56 intact:EBI-6532321|ensemblmetazoa:Y57A10A.18b.1|ensemblmetazoa:Y57A10A.18b.2 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:a5pex6_caeel(display_long)|uniprotkb:Y57A10A.18(orf name)|uniprotkb:pqn-87(gene name)|psi-mi:pqn-87(display_short)|uniprotkb:CELE_Y57A10A.18(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539569|imex:IM-18681-587 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004167(gene)|ensemblmetazoa:Y57A10A.18b.1(transcript)|ensemblmetazoa:Y57A10A.18b.2(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|refseq:NP_001122665.1|wormbase:Y57A10A.18b|uniprotkb:A5PEX6(identity)|wormbase:WBGene00004167(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 39|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:U79ecDJtHc4bqHRcr6eBglpyv5k6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:EB8744AA8E54DCD0|rigid:6DAIGYfZbPHbNJ1p8Ai2znJ99QA false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:G5EE56 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539584|imex:IM-18681-588 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 93|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:A8B1F0DE9FEE0C28|rigid:jeVmRprQM1Rn0b58By1ERKPzWbw false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q4VNJ8 uniprotkb:G5EE56 intact:EBI-2918529 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539614|imex:IM-18681-590 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:F553AD97D23DC7A0|rigid:u3e/pQyAZlYqgQqOnMK5TlemI9I false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U1W1 uniprotkb:G5EE56 intact:EBI-315106|ensemblmetazoa:Y63D3A.5.1|ensemblmetazoa:Y63D3A.5.2 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:tfg_caeel(display_long)|uniprotkb:tfg-1(gene name)|psi-mi:tfg-1(display_short)|uniprotkb:Y63D3A.5(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539599|imex:IM-18681-589 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493462.1|wormbase:Y63D3A.5|ensemblmetazoa:WBGene00006565(gene)|ensemblmetazoa:Y63D3A.5.1(transcript)|ensemblmetazoa:Y63D3A.5.2(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009306"(protein secretion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072595"(maintenance of protein localization in organelle)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|dip:DIP-26017N|reactome:R-CEL-204005|uniprotkb:Q9U1W1(identity)|wormbase:WBGene00006565(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:nqyc7+EyDkiVah2+12hsLFWeNdA6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:CC2A694229640AA1|rigid:nJHYktdok1a1ebiB3ePoXszOlHY false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q9BIF4 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539629|imex:IM-18681-591 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 39|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/09 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 intact-crc:F50C3DBDC530B5D2|rigid:+MF31Eef9+zZGGD0O9klCWfPBMc false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:A8WFL0 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6533929|ensemblmetazoa:ZK381.5b.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:a8wfl0_caeel(display_long)|uniprotkb:ZK381.5(orf name)|uniprotkb:prkl-1(gene name)|psi-mi:prkl-1(display_short)|uniprotkb:CELE_ZK381.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539644|imex:IM-18681-592 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:WBGene00022727(gene)|ensemblmetazoa:ZK381.5b.1(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_741436.2|wormbase:ZK381.5b|uniprotkb:A8WFL0(identity)|wormbase:WBGene00022727(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:fcmrkFYkH8buNRyUpTMTG+NeuoM6239 intact-crc:AA924FD273F0F1B5|rigid:XR6A8/2eFmuDu4WG54f4F85Ox0E false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91001 uniprotkb:Q95PW9 intact:EBI-313007|ensemblmetazoa:B0547.1.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539659|imex:IM-18681-593 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394|uniprotkb:P91001(identity)|wormbase:WBGene00000817(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:845B923B7ED76D7B|rigid:e0Hwju7dZD5a7OwcxtLBisb6I8k false - sufficient binding region:4-59 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:Q95PW9 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539676|imex:IM-18681-594 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:4C84A12F8E79BE2F|rigid:YNs2c+M6DF/e46KXFzfuRSl96Hg false - sufficient binding region:4-59 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19905 uniprotkb:Q95PW9 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539706|imex:IM-18681-596 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N|uniprotkb:Q19905(identity)|wormbase:WBGene00005022(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:53BC75490014AB86|rigid:H/87INR4MTAuh4RXNZQn1V/CO0Y false - sufficient binding region:4-59 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:Q17865 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539691|imex:IM-18681-595 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:AE55A77F69A8CC10|rigid:3JGd8tONes62EQ4bfhRZIabJvhU false sufficient binding region:4-59 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:E3W743 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539721|imex:IM-18681-597 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 intact-crc:928611FC7F90DB87|rigid:zG5xZtd3fXbgrw+GkooYZOtZyeI false sufficient binding region:4-59 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P24892 uniprotkb:Q95PW9 intact:EBI-6538775|ensemblmetazoa:MTCE.25.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:nu4m_caeel(display_long)|uniprotkb:nduo-4(gene name)|psi-mi:nduo-4(display_short)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym)|uniprotkb:nd4(gene name synonym)|uniprotkb:MTCE.25(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539751|imex:IM-18681-599 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:MTCE.25.1(transcript)|ensemblmetazoa:WBGene00010963(gene)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0048039"(ubiquinone binding)|wormbase:MTCE.25|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|refseq:NP_006960.1|uniprotkb:P24892(identity)|wormbase:WBGene00010963(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:hUOrQqUVeMcqRAFSLPuYObqtB3I6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:A41E2AC5C9CE9D0C|rigid:5bdnQ9g+I+XGCnPJRSjDNutWM+c false - sufficient binding region:4-59 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:Q20330 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-322042|ensemblmetazoa:F42C5.10.1 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:q20330_caeel(display_long)|uniprotkb:ifo-1(gene name)|psi-mi:ifo-1(display_short)|uniprotkb:ttm-4(gene name synonym)|uniprotkb:CELE_F42C5.10(orf name)|uniprotkb:F42C5.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539736|imex:IM-18681-598 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) refseq:NP_501170.1|wormbase:F42C5.10|ensemblmetazoa:F42C5.10.1(transcript)|ensemblmetazoa:WBGene00018350(gene)|dip:DIP-27375N|uniprotkb:Q20330(identity)|wormbase:WBGene00018350(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:G/TdIwuOTGQMqaW/I1aJ4GvrtlU6239 intact-crc:B49F7849848F079E|rigid:uOc9C8t2nLCa64D4J5964JzHqjY false sufficient binding region:4-59 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91820 uniprotkb:Q95PW9 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539766|imex:IM-18681-600 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N|uniprotkb:P91820(identity)|wormbase:WBGene00003083(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:D3FF7F80DB844BD4|rigid:lk0SRvUBAWBADJsbhBJ+zbYlI/A false - sufficient binding region:4-59 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:D0IMZ5 uniprotkb:Q95PW9 intact:EBI-6534036|ensemblmetazoa:Y66H1B.2a.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:d0imz5_caeel(display_long)|uniprotkb:Y66H1B.2(orf name)|uniprotkb:fln-1(gene name)|psi-mi:fln-1(display_short)|uniprotkb:CELE_Y66H1B.2(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539781|imex:IM-18681-601 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00022048(gene)|ensemblmetazoa:Y66H1B.2a.1(transcript)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0061038"(uterus morphogenesis)|interpro:IPR044801|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|refseq:NP_001023550.2|wormbase:Y66H1B.2a|interpro:IPR036872|uniprotkb:D0IMZ5(identity)|wormbase:WBGene00022048(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:9hCmcqWxWSY2QYeg05bDz4qoY/U6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:275B72EDF5781F23|rigid:AMcTaIYLwKOVjUN/W0U+EBXO69U false - sufficient binding region:4-59 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23356 uniprotkb:Q95PW9 intact:EBI-326940|uniprotkb:Q8I4B5|uniprotkb:Q8T8M3|uniprotkb:Q95ZI7|uniprotkb:Q9UAN7|uniprotkb:Q9XYC3|uniprotkb:Q9XYC4|ensemblmetazoa:ZC504.4c.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:mig15_caeel(display_long)|uniprotkb:mig-15(gene name)|psi-mi:mig-15(display_short)|uniprotkb:Abnormal cell migration protein 15(gene name synonym)|uniprotkb:ZC504.4(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539796|imex:IM-18681-602 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024971.1|refseq:NP_001024972.1|refseq:NP_001024973.1|refseq:NP_001024974.1|wormbase:ZC504.4a|wormbase:ZC504.4b|wormbase:ZC504.4c|wormbase:ZC504.4d|ensemblmetazoa:WBGene00003247(gene)|ensemblmetazoa:ZC504.4c.1(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010171"(body morphogenesis)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0000165"(MAPK cascade)|dip:DIP-25874N|reactome:R-CEL-2559580|uniprotkb:Q23356(identity)|wormbase:WBGene00003247(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JAFUfFZU8Ja8JtrvD7VNrXOpZCI6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:D6C7BFE26F01E0D3|rigid:7ETlzKP/99Curz35L4N3FXAQZvY false - sufficient binding region:4-59 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:Q17795 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-2316131|ensemblmetazoa:C07G1.4a.1 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:q17795_caeel(display_long)|uniprotkb:wsp-1(gene name)|psi-mi:wsp-1(display_short)|uniprotkb:CELE_C07G1.4(orf name)|uniprotkb:C07G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539811|imex:IM-18681-603 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) refseq:NP_741459.2|wormbase:C07G1.4a|interpro:IPR000697(EVH1)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR033927|interpro:IPR036936|interpro:IPR030214|ensemblmetazoa:C07G1.4a.1(transcript)|ensemblmetazoa:WBGene00006957(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|uniprotkb:Q17795(identity)|wormbase:WBGene00006957(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:YBTDOwM+8a5vUAiihYM6ezASlGY6239 intact-crc:B8D3AEE1684C676A|rigid:s42/VS05eV2fHUPVykSjuh0JXxE false sufficient binding region:117-173 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:P34397 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-321990|ensemblmetazoa:F10E9.3.1 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:ylu3_caeel(display_long)|uniprotkb:F10E9.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539826|imex:IM-18681-604 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) refseq:NP_498826.2|wormbase:F10E9.3|ensemblmetazoa:F10E9.3.1(transcript)|ensemblmetazoa:WBGene00017355(gene)|interpro:IPR040437|dip:DIP-26529N|uniprotkb:P34397(identity)|wormbase:WBGene00017355(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:rI7gLX2TWTqguT53dk5CTySk7to6239 intact-crc:0F7155FFCC33EB6D|rigid:bcoD7gUGIkyXijXJmqI3ZR/vr08 false sufficient binding region:117-173 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A9D4E4 uniprotkb:Q95PW9 intact:EBI-6536798|ensemblmetazoa:F13H6.1b.1|ensemblmetazoa:F13H6.1b.2 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:a9d4e4_caeel(display_long)|uniprotkb:bcl-11(gene name)|psi-mi:bcl-11(display_short)|uniprotkb:CELE_F13H6.1(orf name)|uniprotkb:F13H6.1(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539841|imex:IM-18681-605 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F13H6.1b.1(transcript)|ensemblmetazoa:F13H6.1b.2(transcript)|ensemblmetazoa:WBGene00017430(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001122913.1|wormbase:F13H6.1b|interpro:IPR036236|uniprotkb:A9D4E4(identity)|wormbase:WBGene00017430(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JvzwXvK36+TbPNFYnrUn/O65V9U6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:A5EE51FCA6D6A744|rigid:6TrPs3Iu+QHN+h8KwBLK4f383Vk false - sufficient binding region:117-173 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:G5ECQ3 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-6532702|ensemblmetazoa:F35G12.3a.1|ensemblmetazoa:F35G12.3a.2|uniprotkb:G5EFY9 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:sel5_caeel(display_long)|uniprotkb:Suppressor/enhancer of lin-12 protein 5(gene name synonym)|uniprotkb:F35G12.3(orf name)|uniprotkb:sel-5(gene name)|psi-mi:sel-5(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539856|imex:IM-18681-606 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) ensemblmetazoa:F35G12.3a.1(transcript)|ensemblmetazoa:F35G12.3a.2(transcript)|ensemblmetazoa:WBGene00004762(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|wormbase:F35G12.3b|refseq:NP_001022563.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_001022562.1|wormbase:F35G12.3a|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:G5ECQ3(identity)|wormbase:WBGene00004762(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 50|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:kVuctoNz+qN024pUQQNNP3RnU2A6239 intact-crc:6D29FA86049F6B32|rigid:qtlkE1b4ef4HlhZCFksouF4cj0Q false sufficient binding region:117-173 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34552 uniprotkb:Q95PW9 intact:EBI-322767|uniprotkb:Q7YXC7|uniprotkb:Q8I114|uniprotkb:Q8I115|uniprotkb:Q94159|ensemblmetazoa:R10E12.1b.1|ensemblmetazoa:R10E12.1b.2 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:alxa_caeel(display_long)|uniprotkb:alx-1(gene name)|psi-mi:alx-1(display_short)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 58"(gene name synonym)|uniprotkb:Protein YNK1(gene name synonym)|uniprotkb:pqn-58(gene name synonym)|uniprotkb:R10E12.1(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539886|imex:IM-18681-608 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022713.1|refseq:NP_001022714.1|refseq:NP_001022715.1|refseq:NP_499213.1|wormbase:R10E12.1a|wormbase:R10E12.1b|wormbase:R10E12.1c|wormbase:R10E12.1d|interpro:IPR004328(BRO1)|interpro:IPR025304|ensemblmetazoa:R10E12.1b.1(transcript)|ensemblmetazoa:R10E12.1b.2(transcript)|ensemblmetazoa:WBGene00007010(gene)|go:"GO:0005112"(Notch binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0007032"(endosome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043226"(organelle)|go:"GO:0055037"(recycling endosome)|interpro:IPR038499|uniprotkb:P34552(identity)|wormbase:WBGene00007010(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:xedXAHU8Ms6VcKj1w9YZDHURHHg6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:90B434E69AACBB7F|rigid:9hEJztgOoF72UU3C9/6EMLdPpb0 false - sufficient binding region:117-173 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL2 uniprotkb:Q95PW9 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539871|imex:IM-18681-607 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 57|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:120A251CC7E4E79A|rigid:XRkK6P9VBPNpNzp+gAsCYj7XVTk false - sufficient binding region:117-173 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IAA6 uniprotkb:Q95PW9 intact:EBI-6539901|ensemblmetazoa:Y47G6A.5b.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:q8iaa6_caeel(display_long)|uniprotkb:CELE_Y47G6A.5(orf name)|uniprotkb:Y47G6A.5(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539903|imex:IM-18681-609 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021635(gene)|ensemblmetazoa:Y47G6A.5b.1(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_871806.1|wormbase:Y47G6A.5b|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q8IAA6(identity)|wormbase:WBGene00021635(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:SvM+G9pYBBl1bFy0y3N8GPbnwCk6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:5E8586AAD325B048|rigid:IN+ZNifYJ3uFOcqMiBgb+srhFWg false - sufficient binding region:117-173 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:G5ED57 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-327853|ensemblmetazoa:F22E12.1.1 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:g5ed57_caeel(display_long)|uniprotkb:F22E12.1(orf name)|uniprotkb:CELE_F22E12.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539933|imex:IM-18681-611 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) uniprotkb:O45916(uniprot-removed-ac)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR020901|refseq:NP_505684.2|wormbase:F22E12.1|ensemblmetazoa:F22E12.1.1(transcript)|ensemblmetazoa:WBGene00009058(gene)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036880|uniprotkb:G5ED57(identity)|wormbase:WBGene00009058(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:+Rdyx7pnykvpAExFI2L56AHfbIc6239 intact-crc:1A972D095784BC47|rigid:iuI1WfS5JtbU0dPWJ6voc7cK7ls false sufficient binding region:214-272 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:Q95PW9 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539918|imex:IM-18681-610 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 102|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:8DC39FC086918214|rigid:tT6aVdL97/tRCdK71tIFCeRE08A false - sufficient binding region:214-272 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:Q19319 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-6539952|ensemblmetazoa:F25F2.2.1|uniprotkb:Q19785|uniprotkb:Q21606|uniprotkb:G5EE05|uniprotkb:A0A1C3NSI5 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:cadh4_caeel(display_long)|uniprotkb:cdh-4(gene name)|psi-mi:cdh-4(display_short)|uniprotkb:F25F2.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539948|imex:IM-18681-612 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) ensemblmetazoa:F25F2.2.1(transcript)|ensemblmetazoa:WBGene00000396(gene)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007411"(axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097402"(neuroblast migration)|go:"GO:0098609"(cell-cell adhesion)|reactome:R-CEL-351906|reactome:R-CEL-9013404|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR038765|reactome:R-CEL-6798695|reactome:R-CEL-6809371|refseq:NP_001317871.1|wormbase:F25F2.2|uniprotkb:Q19319(identity)|wormbase:WBGene00000396(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 26|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/08/14 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:CtQsumWNSWGyJm22ZOmr/fk5bSo6239 intact-crc:71BAF65A78241F9C|rigid:YvF5KsejbBosfbG5/oDcRU9WvZQ false sufficient binding region:214-272 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:H2KYS8 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-895932|intact:EBI-6539969|uniprotkb:H2KYS9|uniprotkb:H2KYT0|uniprotkb:Q7JPE2|ensemblmetazoa:F31D5.3b.1|ensemblmetazoa:F31D5.3d.1 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:cpna1_caeel(display_long)|uniprotkb:cpna-1(gene name)|psi-mi:cpna-1(display_short)|uniprotkb:Atypical copine family protein 1(gene name synonym)|uniprotkb:F31D5.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539965|imex:IM-18681-613 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) ensemblmetazoa:WBGene00006495(gene)|uniprotkb:Q19929(uniprot-removed-ac)|interpro:IPR031115|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010734(Copine)|refseq:NP_494736.1|wormbase:F31D5.3b|refseq:NP_494737.1|refseq:NP_871985.1|wormbase:F31D5.3a|wormbase:F31D5.3c|interpro:IPR036465|ensemblmetazoa:F31D5.3b.1(transcript)|ensemblmetazoa:F31D5.3d.1(transcript)|ensemblmetazoa:WBGene00006495(gene)|ensemblmetazoa:WBGene00006495(gene)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031430"(M band)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0060298"(positive regulation of sarcomere organization)|uniprotkb:Q7JPE2(identity)|wormbase:WBGene00006495(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2017/01/20 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:AiwGuTGExS2r+LD+tBBtuMa1tQA6239 intact-crc:493E8871DE71E2F9|rigid:lTvgfdfEQB/ZFNZRiZGIXjS+e7s false sufficient binding region:214-272 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:Q3Y407 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-2317687|uniprotkb:G4SJ35|ensemblmetazoa:F46H5.6.1 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:q3y407_caeel(display_long)|uniprotkb:grd-7(gene name)|psi-mi:grd-7(display_short)|uniprotkb:CELE_F46H5.6(orf name)|uniprotkb:F46H5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539982|imex:IM-18681-614 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) interpro:IPR007284(Ground-like region)|wormbase:F46H5.6|interpro:IPR003882(Pistil-specific extensin-like protein)|ensemblmetazoa:F46H5.6.1(transcript)|ensemblmetazoa:WBGene00001696(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007154"(cell communication)|uniprotkb:Q3Y407(identity)|wormbase:WBGene00001696(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/01/23 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:77+Ww780xL2+LUmBj5htUR6eidA6239 intact-crc:C3F27A53E1D87A33|rigid:Xe1eSg2IJX74u3lnxEjwEMJv3Xw false sufficient binding region:214-272 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17353 uniprotkb:Q95PW9 intact:EBI-321762|uniprotkb:Q27GV0|uniprotkb:Q95QE9|ensemblmetazoa:F54E7.3b.1|ensemblmetazoa:F54E7.3b.2 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:par3_caeel(display_long)|uniprotkb:par-3(gene name)|psi-mi:par-3(display_short)|uniprotkb:F54E7.3(orf name)|uniprotkb:Abnormal embryonic partitioning of cytoplasm protein 3(gene name synonym) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6539997|imex:IM-18681-615 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022607.1|refseq:NP_001040857.1|refseq:NP_498217.2|wormbase:F54E7.3a|wormbase:F54E7.3b|wormbase:F54E7.3c|ensemblmetazoa:F54E7.3b.1(transcript)|ensemblmetazoa:F54E7.3b.2(transcript)|ensemblmetazoa:WBGene00003918(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007338"(single fertilization)|go:"GO:0007369"(gastrulation)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008406"(gonad development)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030154"(cell differentiation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0043186"(P granule)|go:"GO:0043296"(apical junction complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0045179"(apical cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061802"(anterior cell cortex)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|dip:DIP-25317N|uniprotkb:Q17353(identity)|wormbase:WBGene00003918(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tg0WlCFGzovNQANMPpSWW1riAAY6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:E79D1DD61E5F770D|rigid:nT5fg23A/rCCzhOmRTerGu0Qn48 false - sufficient binding region:214-272 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P05690 uniprotkb:Q20498 intact:EBI-313756|ensemblmetazoa:C42D8.2a.1|ensemblmetazoa:C42D8.2a.2 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:vit2_caeel(display_long)|uniprotkb:vit-2(gene name)|psi-mi:vit-2(display_short)|uniprotkb:C42D8.2(orf name) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540027|imex:IM-18681-617 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C42D8.2|refseq:NP_508868.1|ensemblmetazoa:C42D8.2a.1(transcript)|ensemblmetazoa:C42D8.2a.2(transcript)|ensemblmetazoa:WBGene00006926(gene)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031983"(vesicle lumen)|go:"GO:0042718"(yolk granule)|go:"GO:0045735"(nutrient reservoir activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|dip:DIP-27283N|uniprotkb:P05690(identity)|wormbase:WBGene00006926(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:fhE8aRw6juNEdvr6CwyXQilVAEk6239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:80D3BF29A881330A|rigid:sxs57w+3Gc9+THW0MJSAWlATahA false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34552 uniprotkb:Q95PW9 intact:EBI-322767|uniprotkb:Q7YXC7|uniprotkb:Q8I114|uniprotkb:Q8I115|uniprotkb:Q94159|ensemblmetazoa:R10E12.1b.1|ensemblmetazoa:R10E12.1b.2 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:alxa_caeel(display_long)|uniprotkb:alx-1(gene name)|psi-mi:alx-1(display_short)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 58"(gene name synonym)|uniprotkb:Protein YNK1(gene name synonym)|uniprotkb:pqn-58(gene name synonym)|uniprotkb:R10E12.1(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540012|imex:IM-18681-616 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022713.1|refseq:NP_001022714.1|refseq:NP_001022715.1|refseq:NP_499213.1|wormbase:R10E12.1a|wormbase:R10E12.1b|wormbase:R10E12.1c|wormbase:R10E12.1d|interpro:IPR004328(BRO1)|interpro:IPR025304|ensemblmetazoa:R10E12.1b.1(transcript)|ensemblmetazoa:R10E12.1b.2(transcript)|ensemblmetazoa:WBGene00007010(gene)|go:"GO:0005112"(Notch binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0007032"(endosome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043226"(organelle)|go:"GO:0055037"(recycling endosome)|interpro:IPR038499|uniprotkb:P34552(identity)|wormbase:WBGene00007010(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 15|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:xedXAHU8Ms6VcKj1w9YZDHURHHg6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:B4F0F0CF93037FC8|rigid:9hEJztgOoF72UU3C9/6EMLdPpb0 false - sufficient binding region:214-272 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:O44144 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-319794|ensemblmetazoa:C44B12.5.1 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:o44144_caeel(display_long)|uniprotkb:perm-4(gene name)|psi-mi:perm-4(display_short)|uniprotkb:C44B12.5(orf name)|uniprotkb:CELE_C44B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540042|imex:IM-18681-618 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) wormbase:C44B12.5|ensemblmetazoa:C44B12.5.1(transcript)|ensemblmetazoa:WBGene00016638(gene)|refseq:NP_500041.2|dip:DIP-26823N|uniprotkb:O44144(identity)|wormbase:WBGene00016638(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:MSVIEajq6XpoEVL4RehbFBS4z6c6239 intact-crc:3EC0FC56594D7AD9|rigid:AmrUp2Qa4YQoGEPYVvFiXCzqcAE false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P46563 uniprotkb:Q20498 intact:EBI-314454|ensemblmetazoa:F01F1.12a.1|ensemblmetazoa:F01F1.12a.2 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:alf2_caeel(display_long)|uniprotkb:F01F1.12(orf name)|uniprotkb:Aldolase CE-2(gene name synonym)|uniprotkb:aldo-2(gene name)|psi-mi:aldo-2(display_short) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540057|imex:IM-18681-619 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021240.1|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|go:"GO:0006096"(glycolytic process)|ensemblmetazoa:F01F1.12a.1(transcript)|ensemblmetazoa:F01F1.12a.2(transcript)|ensemblmetazoa:WBGene00017166(gene)|go:"GO:0000792"(heterochromatin)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|reactome:R-CEL-70263|reactome:R-CEL-6798695|dip:DIP-24398N|reactome:R-CEL-70171|reactome:R-CEL-114608|wormbase:F01F1.12|uniprotkb:P46563(identity)|wormbase:WBGene00017166(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:E0PrOlgxA2uHJmPnijqKfj8HhUA6239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:AE6071D807B9B66E|rigid:LJex8gR8tLYhtRb17gL6RKZQejo false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45346 uniprotkb:Q20498 intact:EBI-6540076|ensemblmetazoa:F11C7.5.1|ensemblmetazoa:F11C7.5.2 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:osm11_caeel(display_long)|uniprotkb:osm-11(gene name)|psi-mi:osm-11(display_short)|uniprotkb:Osmotic avoidance abnormal protein 11(gene name synonym)|uniprotkb:F11C7.5(orf name) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540072|imex:IM-18681-620 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F11C7.5.1(transcript)|ensemblmetazoa:F11C7.5.2(transcript)|ensemblmetazoa:WBGene00003891(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0005112"(Notch binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0040025"(vulval development)|go:"GO:0045177"(apical part of cell)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|refseq:NP_510823.1|wormbase:F11C7.5|dip:DIP-46050N|uniprotkb:O45346(identity)|wormbase:WBGene00003891(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Jjcad53yq8TvgQrst0Gl4VJaLRM6239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:82F550F6093B4712|rigid:ETFgNidBsU7hn0rfRaqEoRCg4cY false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:P52715 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-319371|ensemblmetazoa:F13D12.6.1|ensemblmetazoa:F13D12.6.2 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:cts12_caeel(display_long)|uniprotkb:ctsa-1.2(gene name)|psi-mi:ctsa-1.2(display_short)|uniprotkb:F13D12.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540089|imex:IM-18681-621 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) refseq:NP_496507.1|wormbase:F13D12.6|ensemblmetazoa:F13D12.6.1(transcript)|ensemblmetazoa:F13D12.6.2(transcript)|ensemblmetazoa:WBGene00008741(gene)|go:"GO:0004185"(serine-type carboxypeptidase activity)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|interpro:IPR033124|dip:DIP-27155N|uniprotkb:P52715(identity)|wormbase:WBGene00008741(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:VObvmGBTIWyxbl5dEg9KgY7OQME6239 intact-crc:12E9D5D1CFC83682|rigid:LoUdDgUA7ma2X7hKC4hwTTUmB3E false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:P54412 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-313179|uniprotkb:Q2PJ76|uniprotkb:Q8I4K9|ensemblmetazoa:F17C11.9a.1|ensemblmetazoa:F17C11.9a.2 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:ef1g_caeel(display_long)|uniprotkb:eef-1G(gene name)|psi-mi:eef-1G(display_short)|uniprotkb:eEF-1B gamma(gene name synonym)|uniprotkb:F17C11.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540104|imex:IM-18681-622 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) wormbase:F17C11.9b|wormbase:F17C11.9c|refseq:NP_505800.1|wormbase:F17C11.9a|ensemblmetazoa:F17C11.9a.1(transcript)|ensemblmetazoa:F17C11.9a.2(transcript)|ensemblmetazoa:WBGene00008920(gene)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006414"(translational elongation)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|refseq:NP_001041100.1|refseq:NP_872125.1|interpro:IPR036282|interpro:IPR036433|dip:DIP-24841N|uniprotkb:P54412(identity)|wormbase:WBGene00008920(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:2BIJ7hlPD7CoxwYAi/JViA0QK4M6239 intact-crc:1186B1D4A53D4BF3|rigid:e97uodTiOcQZRIA+36cJZY9fv4U false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:O01739 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-320093|uniprotkb:Q08I98|ensemblmetazoa:F20H11.5.1 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:oxdd3_caeel(display_long)|uniprotkb:ddo-3(gene name)|psi-mi:ddo-3(display_short)|uniprotkb:F20H11.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540119|imex:IM-18681-623 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|wormbase:WBGene00009800(identity)|uniprotkb:Q20498(identity) refseq:NP_498453.1|wormbase:F20H11.5|ensemblmetazoa:F20H11.5.1(transcript)|ensemblmetazoa:WBGene00017648(gene)|go:"GO:0003884"(D-amino-acid oxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008445"(D-aspartate oxidase activity)|go:"GO:0019478"(D-amino acid catabolic process)|go:"GO:0071949"(FAD binding)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR006181(D-amino acid oxidase, conserved site)|interpro:IPR023209|reactome:R-CEL-389661|dip:DIP-25818N|reactome:R-CEL-9033241|uniprotkb:O01739(identity)|wormbase:WBGene00017648(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:Qpnxvm9eo9A6D78VMRRvxDx2Saw6239 intact-crc:AA6D46B39D13DD20|rigid:4d8AEXaePyDoNeCYo5N4Mq8f+nI false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:Q93557 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-6540138|ensemblmetazoa:F23A7.4.1|ensemblmetazoa:F23A7.4.2 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:q93557_caeel(display_long)|uniprotkb:CELE_F23A7.4(orf name)|uniprotkb:F23A7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540134|imex:IM-18681-624 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) ensemblmetazoa:F23A7.4.1(transcript)|ensemblmetazoa:F23A7.4.2(transcript)|ensemblmetazoa:WBGene00009069(gene)|refseq:NP_510641.1|wormbase:F23A7.4|uniprotkb:Q93557(identity)|wormbase:WBGene00009069(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:3UTxfPccj4cIbwNP+9NRw0H1VJ86239 intact-crc:24186E8D08355504|rigid:gIetuyZ8lo6I3/9012uR9zkNgU4 false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:Q38G52 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-6531104|ensemblmetazoa:F23A7.8.1 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:q38g52_caeel(display_long)|uniprotkb:CELE_F23A7.8(orf name)|uniprotkb:F23A7.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540151|imex:IM-18681-625 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) ensemblmetazoa:F23A7.8.1(transcript)|ensemblmetazoa:WBGene00044638(gene)|refseq:NP_001033542.1|wormbase:F23A7.8|uniprotkb:Q38G52(identity)|wormbase:WBGene00044638(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:08t8o1HdfdDqVXYcNmLYU8i4gzY6239 intact-crc:CB46CE1EB2D32BD5|rigid:kAX1oVltNFFq3YWhFPNPWJ41SxI false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CG71 uniprotkb:Q20498 intact:EBI-6540170|ensemblmetazoa:F25B5.4a.1|ensemblmetazoa:F25B5.4a.2|uniprotkb:P14792|uniprotkb:Q9U1P3 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:ubiq1_caeel(display_long)|uniprotkb:ubq-1(gene name)|psi-mi:ubq-1(display_short)|uniprotkb:ubia(gene name synonym)|uniprotkb:F25B5.4(orf name) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540166|imex:IM-18681-626 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-6807004|reactome:R-CEL-69601|reactome:R-CEL-8849469|reactome:R-CEL-8866652|reactome:R-CEL-901032|reactome:R-CEL-917729|reactome:R-CEL-936440|reactome:R-CEL-983168|reactome:R-CEL-110320|reactome:R-CEL-382556|reactome:R-CEL-4641258|reactome:R-CEL-532668|reactome:R-CEL-5675221|reactome:R-CEL-5689603|reactome:R-CEL-5689877|reactome:R-CEL-5689880|reactome:R-CEL-5689896|reactome:R-CEL-5689901|reactome:R-CEL-5696395|reactome:R-CEL-6781823|reactome:R-CEL-5632684|reactome:R-CEL-69017|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-9033241|ensemblmetazoa:F25B5.4a.1(transcript)|ensemblmetazoa:F25B5.4a.2(transcript)|ensemblmetazoa:WBGene00006727(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-CEL-2173796|reactome:R-CEL-3134975|reactome:R-CEL-5358346|reactome:R-CEL-5687128|reactome:R-CEL-5696394|wormbase:F25B5.4|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-5655862|reactome:R-CEL-5696397|reactome:R-CEL-8932339|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|refseq:NP_741157.1|reactome:R-CEL-9020702|reactome:R-CEL-1234176|reactome:R-CEL-1253288|interpro:IPR029071|reactome:R-CEL-8948751|reactome:R-CEL-912631|reactome:R-CEL-2672351|reactome:R-CEL-68949|reactome:R-CEL-182971|reactome:R-CEL-2173795|reactome:R-CEL-69231|reactome:R-CEL-8948747|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-2173788|reactome:R-CEL-349425|reactome:R-CEL-8854050|reactome:R-CEL-8863795|reactome:R-CEL-8866654|reactome:R-CEL-8951664|reactome:R-CEL-917937|reactome:R-CEL-9646399|uniprotkb:P0CG71(identity)|wormbase:WBGene00006727(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Gr5YaJF9WbSB2Fce+L2F9Qfga0s6239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:EF132711651C0C03|rigid:rMsss1gCIU8kSWiLuBA5HH5o3P0 false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02358 uniprotkb:Q20498 intact:EBI-6540183|ensemblmetazoa:F35E12.6.1|ensemblmetazoa:F35E12.6.2|ensemblmetazoa:F35E12.6.3 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:o02358_caeel(display_long)|uniprotkb:CELE_F35E12.6(orf name)|uniprotkb:F35E12.6(orf name) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540185|imex:IM-18681-627 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F35E12.6.1(transcript)|ensemblmetazoa:F35E12.6.2(transcript)|ensemblmetazoa:F35E12.6.3(transcript)|ensemblmetazoa:WBGene00009430(gene)|go:"GO:0045087"(innate immune response)|interpro:IPR003366(CUB-like region)|refseq:NP_506401.2|wormbase:F35E12.6|interpro:IPR035914|uniprotkb:O02358(identity)|wormbase:WBGene00009430(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:I8BMbaQaEUQi8Uafk5Mkh6KrijY6239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:3587ADCE47F41200|rigid:encfqKBzEbUELKDlJnKhDh//ynE false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20173 uniprotkb:Q20498 intact:EBI-329306|ensemblmetazoa:F38E9.5.1|ensemblmetazoa:F38E9.5.2 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:q20173_caeel(display_long)|uniprotkb:twf-2(gene name)|psi-mi:twf-2(display_short)|uniprotkb:CELE_F38E9.5(orf name)|uniprotkb:F38E9.5(orf name) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540200|imex:IM-18681-628 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_510669.1|wormbase:F38E9.5|dip:DIP-25889N|interpro:IPR028458|interpro:IPR029006|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|ensemblmetazoa:F38E9.5.1(transcript)|ensemblmetazoa:F38E9.5.2(transcript)|ensemblmetazoa:WBGene00018187(gene)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030016"(myofibril)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|uniprotkb:Q20173(identity)|wormbase:WBGene00018187(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:oNgUiiwGVigZUluykvaqYlfdq0s6239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:A366B8D3FC5160C9|rigid:Z2lOQeLnmSGbrOuXmC2FgLVhiSc false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:P43508 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-322333|ensemblmetazoa:F44C4.3.1 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:cpr4_caeel(display_long)|uniprotkb:cpr-4(gene name)|psi-mi:cpr-4(display_short)|uniprotkb:F44C4.3(orf name)|uniprotkb:Cysteine protease-related 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540215|imex:IM-18681-629 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) refseq:NP_504682.1|wormbase:F44C4.3|ensemblmetazoa:F44C4.3.1(transcript)|ensemblmetazoa:WBGene00000784(gene)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0034644"(cellular response to UV)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|dip:DIP-25376N|uniprotkb:P43508(identity)|wormbase:WBGene00000784(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:EpYs+S51umPPmQu+pCfoO67Hmw06239 intact-crc:45E3D3F3D71DF974|rigid:IR82XbHqYh9567GTh8Z9qDlkT/A false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:Q10454 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-314590|uniprotkb:Q86NG9|ensemblmetazoa:F46H5.3a.1|ensemblmetazoa:F46H5.3a.2|ensemblmetazoa:F46H5.3a.3|ensemblmetazoa:F46H5.3a.4 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:karg1_caeel(display_long)|uniprotkb:F46H5.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540230|imex:IM-18681-630 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) refseq:NP_509217.2|refseq:NP_872253.1|wormbase:F46H5.3a|wormbase:F46H5.3b|ensemblmetazoa:F46H5.3a.1(transcript)|ensemblmetazoa:F46H5.3a.2(transcript)|ensemblmetazoa:F46H5.3a.3(transcript)|ensemblmetazoa:F46H5.3a.4(transcript)|ensemblmetazoa:WBGene00018519(gene)|go:"GO:0004054"(arginine kinase activity)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|dip:DIP-26821N|uniprotkb:Q10454(identity)|wormbase:WBGene00018519(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:rnThQVpZosFEEurB5xLlL13wYC86239 intact-crc:5095277773597A8B|rigid:7M8VLtMLy8cLCXxltBS4j/qBkt0 false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:Q20720 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-331536|ensemblmetazoa:F53F4.11.1|ensemblmetazoa:F53F4.11.2|ensemblmetazoa:F53F4.11.3 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:q20720_caeel(display_long)|uniprotkb:F53F4.11(orf name)|uniprotkb:CELE_F53F4.11(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540245|imex:IM-18681-631 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) refseq:NP_506375.1|wormbase:F53F4.11|dip:DIP-24448N|ensemblmetazoa:F53F4.11.1(transcript)|ensemblmetazoa:F53F4.11.2(transcript)|ensemblmetazoa:F53F4.11.3(transcript)|ensemblmetazoa:WBGene00009993(gene)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR028364|interpro:IPR023674|uniprotkb:Q20720(identity)|wormbase:WBGene00009993(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:D1o1lJ3M8GrLIt2nNhsHwiNGOxU6239 intact-crc:9FCA7B7E2C36C6BF|rigid:VMoHvx5c3n1BIIcXie0+5GEZvrw false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XUD8 uniprotkb:Q20498 intact:EBI-2418456|ensemblmetazoa:F55G11.2.1 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:q9xud8_caeel(display_long)|uniprotkb:F55G11.2(orf name)|uniprotkb:CELE_F55G11.2(orf name) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540260|imex:IM-18681-632 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003366(CUB-like region)|refseq:NP_502483.1|wormbase:F55G11.2|ensemblmetazoa:F55G11.2.1(transcript)|ensemblmetazoa:WBGene00010123(gene)|go:"GO:0045087"(innate immune response)|uniprotkb:Q9XUD8(identity)|wormbase:WBGene00010123(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4a0IpfIuOhgcAWINAYOb6i6snH06239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:D19EF66ECA709A6C|rigid:lejOXEsFHGFkY01Ra/wZ6lanWC4 false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55956 uniprotkb:Q20498 intact:EBI-313689|uniprotkb:Q9TXI5|ensemblmetazoa:H22K11.1.1 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:asp3_caeel(display_long)|uniprotkb:asp-3(gene name)|psi-mi:asp-3(display_short)|uniprotkb:H22K11.1(orf name) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540290|imex:IM-18681-634 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-5683826|reactome:R-CEL-2022377|wormbase:H22K11.1|refseq:NP_509142.2|ensemblmetazoa:H22K11.1.1(transcript)|ensemblmetazoa:WBGene00000216(gene)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0008219"(cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0070265"(necrotic cell death)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR021109|interpro:IPR033121|reactome:R-CEL-2132295|dip:DIP-26574N|uniprotkb:P55956(identity)|wormbase:WBGene00000216(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:3di+vT8IFrs/9rmcA2d0BOi1ZZQ6239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:DB1D0D69FE1F36B8|rigid:cpGeUOo2od+idy8uBQyROJBak88 false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20950 uniprotkb:Q20498 intact:EBI-312868|ensemblmetazoa:F57F5.1.1 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:q20950_caeel(display_long)|uniprotkb:cpr-9(gene name)|psi-mi:cpr-9(display_short)|uniprotkb:CELE_F57F5.1(orf name)|uniprotkb:F57F5.1(orf name) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540275|imex:IM-18681-633 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506011.2|wormbase:F57F5.1|ensemblmetazoa:F57F5.1.1(transcript)|ensemblmetazoa:WBGene00010204(gene)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|dip:DIP-24447N|uniprotkb:Q20950(identity)|wormbase:WBGene00010204(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:8sXE02/TDt7bidRsEagvVGJS3eE6239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:A3A3C95C0A1A5E37|rigid:1GOX/Fm1Pn+6ygM2vwCLGMv0XWI false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:O45628 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-6540305|ensemblmetazoa:H40L08.1.1 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:o45628_caeel(display_long)|uniprotkb:CELE_H40L08.1(orf name)|uniprotkb:H40L08.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540307|imex:IM-18681-635 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) reactome:R-CEL-6798695|ensemblmetazoa:H40L08.1.1(transcript)|ensemblmetazoa:WBGene00010433(gene)|reactome:R-CEL-8980692|interpro:IPR009060(UBA-like)|refseq:NP_510506.1|wormbase:H40L08.1|interpro:IPR029071|uniprotkb:O45628(identity)|wormbase:WBGene00010433(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:6G1r556DstUCZIKM5181tibTkfE6239 intact-crc:DF6EA5BC915B278C|rigid:HWdDTxCICz5mz71YIqhpxciEnoc false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:P18948 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-320735|uniprotkb:O45176|uniprotkb:Q7KPP7|uniprotkb:Q7YXH2|ensemblmetazoa:K07H8.6c.1 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:vit6_caeel(display_long)|uniprotkb:vit-6(gene name)|psi-mi:vit-6(display_short)|uniprotkb:K07H8.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540322|imex:IM-18681-636 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) refseq:NP_001023274.1|refseq:NP_001023275.1|refseq:NP_001023276.1|wormbase:K07H8.6a|wormbase:K07H8.6b|wormbase:K07H8.6c|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR001846(von Willebrand factor, type D)|ensemblmetazoa:K07H8.6c.1(transcript)|ensemblmetazoa:WBGene00006930(gene)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0045735"(nutrient reservoir activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904109"(positive regulation of cholesterol import)|go:"GO:1904807"(negative regulation of protein oxidation)|uniprotkb:P18948(identity)|wormbase:WBGene00006930(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:Rriiqcl0XiZg+M/MRxOmBfaDmWs6239 intact-crc:B61D750BFD81006C|rigid:2pg7ksUIiXv64tcGsTsOsUFqKvM false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P90925 uniprotkb:Q20498 intact:EBI-318020|ensemblmetazoa:K08F8.4a.1|uniprotkb:I2HA98|uniprotkb:Q9XYQ5 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:ph4h_caeel(display_long)|uniprotkb:pah-1(gene name)|psi-mi:pah-1(display_short)|uniprotkb:Phe-4-monooxygenase(gene name synonym)|uniprotkb:Biogenic amine synthesis protein 2(gene name synonym)|uniprotkb:K08F8.4(orf name)|uniprotkb:bas-2(gene name synonym)|uniprotkb:Tryptophan 5-monooxygenase(gene name synonym) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540337|imex:IM-18681-637 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:K08F8.4a|refseq:NP_001254185.1|ensemblmetazoa:K08F8.4a.1(transcript)|ensemblmetazoa:WBGene00000240(gene)|go:"GO:0000003"(reproduction)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0004510"(tryptophan 5-monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006569"(tryptophan catabolic process)|go:"GO:0006571"(tyrosine biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040002"(collagen and cuticulin-based cuticle development)|go:"GO:0042438"(melanin biosynthetic process)|interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR005961(Phenylalanine-4-hydroxylase, tetrameric form)|interpro:IPR018301|interpro:IPR019773|interpro:IPR019774|interpro:IPR036329|interpro:IPR036951|interpro:IPR041912|dip:DIP-25264N|refseq:NP_001254184.1|wormbase:K08F8.4b|reactome:R-CEL-8964208|uniprotkb:P90925(identity)|wormbase:WBGene00000240(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Ceg0vwDFmdjAryQGSjHA7yBFPXc6239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:99B6BE1B5A28A6A2|rigid:epY2qMhCOIP5zm5a/jqr+9atNvM false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:P24885 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-6540356|ensemblmetazoa:MTCE.3.1 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:nu6m_caeel(display_long)|uniprotkb:nduo-6(gene name)|psi-mi:nduo-6(display_short)|uniprotkb:NADH dehydrogenase subunit 6(gene name synonym)|uniprotkb:nd6(gene name synonym)|uniprotkb:MTCE.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540352|imex:IM-18681-638 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) ensemblmetazoa:MTCE.3.1(transcript)|ensemblmetazoa:WBGene00010957(gene)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0070469"(respirasome)|wormbase:MTCE.3|refseq:NP_006953.1|uniprotkb:P24885(identity)|wormbase:WBGene00010957(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:dtwgbQb1xPrH/WhtPbNNf0g5jiM6239 intact-crc:99060BD51715ABE7|rigid:dGh4BAkoffY1+my9kml8m7ZQxPU false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16520 uniprotkb:Q20498 intact:EBI-6540373|uniprotkb:S6EZT6|ensemblmetazoa:T05H4.6a.1 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:erf1_caeel(display_long)|uniprotkb:erfa-1(gene name)|psi-mi:erfa-1(display_short)|uniprotkb:etf-1(gene name synonym)|uniprotkb:T05H4.6(orf name) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540369|imex:IM-18681-639 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T05H4.6b|wormbase:T05H4.6a|ensemblmetazoa:T05H4.6a.1(transcript)|ensemblmetazoa:WBGene00020269(gene)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0005829"(cytosol)|go:"GO:0016149"(translation release factor activity, codon specific)|go:"GO:0018444"(translation release factor complex)|go:"GO:1990825"(sequence-specific mRNA binding)|refseq:NP_001294675.1|interpro:IPR024049|interpro:IPR004403(Peptide chain release factor eRF/aRF subunit 1)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|reactome:R-CEL-72764|reactome:R-CEL-975956|reactome:R-CEL-975957|interpro:IPR029064|interpro:IPR042226|uniprotkb:O16520(identity)|wormbase:WBGene00020269(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/01/24 rogid:cDmRpNVbK1wXmrCNmjdUKCApn6k6239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:59D1F0ACA9DA8ED8|rigid:E+eQNAYe/1IvoR74gld0FOzbk/Q false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:Q9XUP2 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-6540390|ensemblmetazoa:T16G1.6.1 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:q9xup2_caeel(display_long)|uniprotkb:CELE_T16G1.6(orf name)|uniprotkb:T16G1.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540386|imex:IM-18681-640 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) ensemblmetazoa:T16G1.6.1(transcript)|ensemblmetazoa:WBGene00011800(gene)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012877(Protein of unknown function DUF1679, Caenorhabditis species)|interpro:IPR015897(CHK kinase-like)|refseq:NP_506234.2|wormbase:T16G1.6|uniprotkb:Q9XUP2(identity)|wormbase:WBGene00011800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:lOyMstAIBcNyspWjzg1qyJth+z46239 intact-crc:5EB47F1DAFA88056|rigid:CrIM0yVGcLVXl36zr7A7WbeVXAs false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6533373 uniprotkb:Q20498 - intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:g3mu69_caeel(display_short)|psi-mi:EBI-6533373(display_long)|uniprotkb:T27E9.1(orf name)|uniprotkb:ant-1.1(gene name)|psi-mi:ant-1.1(display_short)|uniprotkb:CELE_T27E9.1(orf name) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540403|imex:IM-18681-641 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:G3MU69(uniprot-removed-ac)|uniprotkb:G3MU69(identity)|wormbase:WBGene00006439(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:haVkJWSnhAa5irdfMD7lj2O3KY46239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:E6E27FD2CD7EE48C|rigid:oFRAt8tRxPsPCyU/8roBzGAMhIk false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:G5EDW8 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-6540422|ensemblmetazoa:VF13D12L.3.1|ensemblmetazoa:VF13D12L.3.2 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:g5edw8_caeel(display_long)|uniprotkb:CELE_VF13D12L.3(orf name)|uniprotkb:VF13D12L.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540418|imex:IM-18681-642 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) ensemblmetazoa:VF13D12L.3.1(transcript)|ensemblmetazoa:WBGene00012149(gene)|go:"GO:0016491"(oxidoreductase activity)|ensemblmetazoa:VF13D12L.3.2(transcript)|interpro:IPR003767(Malate/L-lactate dehydrogenase)|refseq:NP_496500.1|wormbase:VF13D12L.3|interpro:IPR043144|interpro:IPR043143|interpro:IPR036111|uniprotkb:G5EDW8(identity)|wormbase:WBGene00012149(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:JmOE+NSaDD9uL0uzkprE9j9uBU06239 intact-crc:ED0BD1DCFFBDE460|rigid:fGQ+D6ybK1keI4XUjyOlNndiKwI false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XUL7 uniprotkb:Q20498 intact:EBI-332054|ensemblmetazoa:W04E12.8.1 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:q9xul7_caeel(display_long)|uniprotkb:clec-50(gene name)|psi-mi:clec-50(display_short)|uniprotkb:CELE_W04E12.8(orf name)|uniprotkb:W04E12.8(orf name) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540435|imex:IM-18681-643 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_507830.1|wormbase:W04E12.8|dip:DIP-26848N|ensemblmetazoa:W04E12.8.1(transcript)|ensemblmetazoa:WBGene00012253(gene)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|uniprotkb:Q9XUL7(identity)|wormbase:WBGene00012253(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:bkv3+t7ymqBdx6PjQ8RnoKN5rdw6239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:96472E1E784EF2B9|rigid:+nBzlmKcTk3OH5tajDTX2Oszrik false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:Q9NF14 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-313743|ensemblmetazoa:Y105E8B.4.1 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:bat40_caeel(display_long)|uniprotkb:Y105E8B.4(orf name)|uniprotkb:bath-40(gene name)|psi-mi:bath-40(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540450|imex:IM-18681-644 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) refseq:NP_493543.1|wormbase:Y105E8B.4|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|ensemblmetazoa:WBGene00013689(gene)|ensemblmetazoa:Y105E8B.4.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|reactome:R-CEL-5632684|dip:DIP-25100N|uniprotkb:Q9NF14(identity)|wormbase:WBGene00013689(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:geY3IvHdC//NnhOTYIP2qZlM2+Y6239 intact-crc:DE5A57EFD8782E29|rigid:uuFLJgEfHtNzrr6kXnLZcwi5THY false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED00 uniprotkb:Q20498 intact:EBI-6540465|ensemblmetazoa:Y39E4B.8.1 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 psi-mi:zig8_caeel(display_long)|uniprotkb:2 Ig domain protein zig-8(gene name synonym)|uniprotkb:Y39E4B.8(orf name)|uniprotkb:zig-8(gene name)|psi-mi:zig-8(display_short) psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540467|imex:IM-18681-645 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6PLL|ensemblmetazoa:WBGene00006985(gene)|ensemblmetazoa:Y39E4B.8.1(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0050808"(synapse organization)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_499714.1|wormbase:Y39E4B.8|rcsb pdb:6ON9|rcsb pdb:6ONB|interpro:IPR036179|interpro:IPR037448|uniprotkb:G5ED00(identity)|wormbase:WBGene00006985(identity) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:jj3uoO2z4YeYp8qiri4MJ1GWuX46239 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 intact-crc:8746431F4CD471AC|rigid:/HUqTe7RdhldgQ1jzGBR9TjG6oA false - sufficient binding region:167-242 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4RZC8 uniprotkb:P91001 intact:EBI-6540486|ensemblmetazoa:F56D12.4a.1 intact:EBI-313007|ensemblmetazoa:B0547.1.1 psi-mi:g4rzc8_caeel(display_long)|uniprotkb:F56D12.4(orf name)|uniprotkb:jip-1(gene name)|psi-mi:jip-1(display_short)|uniprotkb:CELE_F56D12.4(orf name) psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540482|imex:IM-18681-646 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F56D12.4a.1(transcript)|ensemblmetazoa:WBGene00002176(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0046328"(regulation of JNK cascade)|refseq:NP_001033330.1|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:F56D12.4a|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:G4RZC8(identity)|wormbase:WBGene00002176(identity) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394|uniprotkb:P91001(identity)|wormbase:WBGene00000817(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/04/25 rogid:De9dyDC1TvB5bk1bsPDoJoF0XVk6239 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 intact-crc:803D78E265906F9C|rigid:1DJ0tavD6MdzcqZHm4Cd4O6N/HU false sufficient binding region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4RZC8 uniprotkb:P05690 intact:EBI-6540486|ensemblmetazoa:F56D12.4a.1 intact:EBI-313756|ensemblmetazoa:C42D8.2a.1|ensemblmetazoa:C42D8.2a.2 psi-mi:g4rzc8_caeel(display_long)|uniprotkb:F56D12.4(orf name)|uniprotkb:jip-1(gene name)|psi-mi:jip-1(display_short)|uniprotkb:CELE_F56D12.4(orf name) psi-mi:vit2_caeel(display_long)|uniprotkb:vit-2(gene name)|psi-mi:vit-2(display_short)|uniprotkb:C42D8.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540499|imex:IM-18681-647 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F56D12.4a.1(transcript)|ensemblmetazoa:WBGene00002176(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0046328"(regulation of JNK cascade)|refseq:NP_001033330.1|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:F56D12.4a|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:G4RZC8(identity)|wormbase:WBGene00002176(identity) wormbase:C42D8.2|refseq:NP_508868.1|ensemblmetazoa:C42D8.2a.1(transcript)|ensemblmetazoa:C42D8.2a.2(transcript)|ensemblmetazoa:WBGene00006926(gene)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031983"(vesicle lumen)|go:"GO:0042718"(yolk granule)|go:"GO:0045735"(nutrient reservoir activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|dip:DIP-27283N|uniprotkb:P05690(identity)|wormbase:WBGene00006926(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/04/25 rogid:De9dyDC1TvB5bk1bsPDoJoF0XVk6239 rogid:fhE8aRw6juNEdvr6CwyXQilVAEk6239 intact-crc:34D4ECFA26AF2A44|rigid:f/cGME4xV/Si/w9bTEIW7QzVQqg false sufficient binding region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4RZC8 uniprotkb:O16928 intact:EBI-6540486|ensemblmetazoa:F56D12.4a.1 intact:EBI-6540514|ensemblmetazoa:F25G6.9.1 psi-mi:g4rzc8_caeel(display_long)|uniprotkb:F56D12.4(orf name)|uniprotkb:jip-1(gene name)|psi-mi:jip-1(display_short)|uniprotkb:CELE_F56D12.4(orf name) psi-mi:o16928_caeel(display_long)|uniprotkb:CELE_F25G6.9(orf name)|uniprotkb:F25G6.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540516|imex:IM-18681-648 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F56D12.4a.1(transcript)|ensemblmetazoa:WBGene00002176(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0046328"(regulation of JNK cascade)|refseq:NP_001033330.1|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:F56D12.4a|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:G4RZC8(identity)|wormbase:WBGene00002176(identity) interpro:IPR003210(Signal recognition particle, SRP14 subunit)|ensemblmetazoa:F25G6.9.1(transcript)|ensemblmetazoa:WBGene00017800(gene)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0045047"(protein targeting to ER)|refseq:NP_505209.2|wormbase:F25G6.9|interpro:IPR016024(Armadillo-type fold)|uniprotkb:O16928(identity)|wormbase:WBGene00017800(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/04/25 rogid:De9dyDC1TvB5bk1bsPDoJoF0XVk6239 rogid:MMmI9I0xs+iTIehArR3v6b1qh7M6239 intact-crc:F390304B3BEC221C|rigid:qn/YId9zt2ypv0vjzKXxYMtRQ60 false sufficient binding region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19905 uniprotkb:G4RZC8 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 intact:EBI-6540486|ensemblmetazoa:F56D12.4a.1 psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:g4rzc8_caeel(display_long)|uniprotkb:F56D12.4(orf name)|uniprotkb:jip-1(gene name)|psi-mi:jip-1(display_short)|uniprotkb:CELE_F56D12.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540531|imex:IM-18681-649 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N|uniprotkb:Q19905(identity)|wormbase:WBGene00005022(identity) ensemblmetazoa:F56D12.4a.1(transcript)|ensemblmetazoa:WBGene00002176(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0046328"(regulation of JNK cascade)|refseq:NP_001033330.1|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:F56D12.4a|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:G4RZC8(identity)|wormbase:WBGene00002176(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/04/25 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 rogid:De9dyDC1TvB5bk1bsPDoJoF0XVk6239 intact-crc:EF5153D59C3F0504|rigid:m7Tj5PkDQRFblKuQFwphprcUxA8 false - sufficient binding region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4RZC8 intact:EBI-6533373 intact:EBI-6540486|ensemblmetazoa:F56D12.4a.1 - psi-mi:g4rzc8_caeel(display_long)|uniprotkb:F56D12.4(orf name)|uniprotkb:jip-1(gene name)|psi-mi:jip-1(display_short)|uniprotkb:CELE_F56D12.4(orf name) psi-mi:g3mu69_caeel(display_short)|psi-mi:EBI-6533373(display_long)|uniprotkb:T27E9.1(orf name)|uniprotkb:ant-1.1(gene name)|psi-mi:ant-1.1(display_short)|uniprotkb:CELE_T27E9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540546|imex:IM-18681-650 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F56D12.4a.1(transcript)|ensemblmetazoa:WBGene00002176(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0046328"(regulation of JNK cascade)|refseq:NP_001033330.1|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:F56D12.4a|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:G4RZC8(identity)|wormbase:WBGene00002176(identity) uniprotkb:G3MU69(uniprot-removed-ac)|uniprotkb:G3MU69(identity)|wormbase:WBGene00006439(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/04/25 rogid:De9dyDC1TvB5bk1bsPDoJoF0XVk6239 rogid:haVkJWSnhAa5irdfMD7lj2O3KY46239 intact-crc:2AA0350865BA2B87|rigid:YPPCCU/eCFsjgOUhI4kW1FNtfIY false sufficient binding region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4J2 intact:EBI-6540576 intact:EBI-6540578|ensemblmetazoa:F59D8.1.1 - psi-mi:vit3_caeel(display_long)|uniprotkb:vit-3(gene name)|psi-mi:vit-3(display_short)|uniprotkb:F59D8.1(orf name) psi-mi:g5ecg5_caeel(display_short)|psi-mi:EBI-6540576(display_long)|uniprotkb:ZK1151.1(orf name)|uniprotkb:vab-10(gene name)|psi-mi:vab-10(display_short)|uniprotkb:CELE_ZK1151.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540580|imex:IM-18681-652 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F59D8.1.1(transcript)|ensemblmetazoa:WBGene00006927(gene)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0045735"(nutrient reservoir activity)|refseq:NP_001294839.1|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|wormbase:F59D8.1|uniprotkb:Q9N4J2(identity)|wormbase:WBGene00006927(identity) uniprotkb:G5ECG5(uniprot-removed-ac)|uniprotkb:G5ECG5(identity)|wormbase:WBGene00006876(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:wT7EJ5oZKO9uYKDXVatrd69SsVQ6239 rogid:riVHU5Xpw7K9oQCE4DIP2G0Yoes6239 intact-crc:3BB56A29AB6FE2F0|rigid:tB9yEJ5ITWfwR8aifAhvUsIUFMY false - sufficient binding region:820-873 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED84 uniprotkb:G4RZC8 intact:EBI-312469|ensemblmetazoa:W02G9.2a.1 intact:EBI-6540486|ensemblmetazoa:F56D12.4a.1 psi-mi:klhl8_caeel(display_long)|uniprotkb:kel-8(gene name)|psi-mi:kel-8(display_short)|uniprotkb:W02G9.2(orf name) psi-mi:g4rzc8_caeel(display_long)|uniprotkb:F56D12.4(orf name)|uniprotkb:jip-1(gene name)|psi-mi:jip-1(display_short)|uniprotkb:CELE_F56D12.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540561|imex:IM-18681-651 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O61899(uniprot-removed-ac)|reactome:R-CEL-8951664|ensemblmetazoa:W02G9.2a.1(transcript)|ensemblmetazoa:WBGene00020952(gene)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|reactome:R-CEL-983168|wormbase:W02G9.2a|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|refseq:NP_503729.4|uniprotkb:G5ED84(identity)|wormbase:WBGene00020952(identity) ensemblmetazoa:F56D12.4a.1(transcript)|ensemblmetazoa:WBGene00002176(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0046328"(regulation of JNK cascade)|refseq:NP_001033330.1|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:F56D12.4a|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:G4RZC8(identity)|wormbase:WBGene00002176(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/04/25 rogid:U6YpxxZM4gZixpdvsBb0hGIph9E6239 rogid:De9dyDC1TvB5bk1bsPDoJoF0XVk6239 intact-crc:CC1F464FE4D7A0B9|rigid:80WCxMGOvGtx2Mg2r2/xKAHvwXw false - sufficient binding region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02365 intact:EBI-6540576 intact:EBI-322131|ensemblmetazoa:W10G6.3.1 - psi-mi:ifa2_caeel(display_long)|uniprotkb:mua-6(gene name)|psi-mi:mua-6(display_short)|uniprotkb:Cel IF A2(gene name synonym)|uniprotkb:Intermediate filament protein A2(gene name synonym)|uniprotkb:ifa-2(gene name synonym)|uniprotkb:W10G6.3(orf name) psi-mi:g5ecg5_caeel(display_short)|psi-mi:EBI-6540576(display_long)|uniprotkb:ZK1151.1(orf name)|uniprotkb:vab-10(gene name)|psi-mi:vab-10(display_short)|uniprotkb:CELE_ZK1151.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540595|imex:IM-18681-653 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_510648.1|wormbase:W10G6.3|reactome:R-CEL-4419969|ensemblmetazoa:W10G6.3.1(transcript)|ensemblmetazoa:WBGene00003485(gene)|go:"GO:0005882"(intermediate filament)|go:"GO:0030056"(hemidesmosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR036415|interpro:IPR039008|dip:DIP-26450N|uniprotkb:O02365(identity)|wormbase:WBGene00003485(identity) uniprotkb:G5ECG5(uniprot-removed-ac)|uniprotkb:G5ECG5(identity)|wormbase:WBGene00006876(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:pdWSrp+seluBAT//FOdDkdlq7786239 rogid:riVHU5Xpw7K9oQCE4DIP2G0Yoes6239 intact-crc:62C80E7D1C46D673|rigid:WG3DRC9N2UTAbNhrQbSjA7Osnfc false - sufficient binding region:820-873 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:P39055 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540610|imex:IM-18681-654 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 25|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:A210863C4861555A|rigid:1osvjpZSpAVuMsvcfbirh6m9Trk false sufficient binding region:252-309 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED89 uniprotkb:G5ECK4 intact:EBI-6540629|ensemblmetazoa:C26C6.5b.1|ensemblmetazoa:C26C6.5b.2|intact:EBI-6729262|uniprotkb:G5ECM2 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:dcp66_caeel(display_long)|uniprotkb:Deacetylase complex protein dcp-66(gene name synonym)|uniprotkb:C26C6.5(orf name)|uniprotkb:dcp-66(gene name)|psi-mi:dcp-66(display_short) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540625|imex:IM-18681-655 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492111.3|ensemblmetazoa:C26C6.5b.1(transcript)|ensemblmetazoa:C26C6.5b.2(transcript)|ensemblmetazoa:WBGene00000938(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|reactome:R-CEL-3214815|reactome:R-CEL-8943724|refseq:NP_871831.3|wormbase:C26C6.5b|interpro:IPR040386|wormbase:C26C6.5a|uniprotkb:G5ECM2(identity)|wormbase:WBGene00000938(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/12/11 rogid:gVtNH6X8K5a2bwI2Ihc3BV7ouIc6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:9113276DE2855698|rigid:xH0GEIFhcffeeZX30ATQRr+6jko false - sufficient binding region:252-309 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q19905 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540642|imex:IM-18681-656 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N|uniprotkb:Q19905(identity)|wormbase:WBGene00005022(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 intact-crc:C61F6528F9F44BF9|rigid:EJK+naSIKO18unCwGHcDRbQQ1JA false sufficient binding region:252-309 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:G5ECL2 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540657|imex:IM-18681-657 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 64|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 intact-crc:799189D2D54CD1AB|rigid:BoXbf6GxpIiSjRP2BdXR1gh4Aak false sufficient binding region:252-309 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE04 uniprotkb:G5ECK4 intact:EBI-896154|ensemblmetazoa:T12D8.8.1|ensemblmetazoa:T12D8.8.2 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:g5ee04_caeel(display_long)|uniprotkb:T12D8.8(orf name)|uniprotkb:hip-1(gene name)|psi-mi:hip-1(display_short)|uniprotkb:CELE_T12D8.8(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540672|imex:IM-18681-658 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3371453|uniprotkb:O45786(uniprot-removed-ac)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:NP_499811.1|interpro:IPR034649|wormbase:T12D8.8|interpro:IPR041243|ensemblmetazoa:T12D8.8.1(transcript)|ensemblmetazoa:T12D8.8.2(transcript)|ensemblmetazoa:WBGene00011735(gene)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030017"(sarcomere)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0065003"(protein-containing complex assembly)|uniprotkb:G5EE04(identity)|wormbase:WBGene00011735(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 27|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:FxNGPNqdfNwYyRSe/i9ru5HnyjY6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:CC7642EA0D7A8643|rigid:C4DzBtkbWWVUETgSgums4lGbXGY false - sufficient binding region:252-309 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:G5ECK4 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540687|imex:IM-18681-659 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:D4596FB4B0438A83|rigid:vS2a3igp8DPzj5UvcIvahVqcqkA false - sufficient binding region:252-309 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:V6CKC3 uniprotkb:G5ECK4 intact:EBI-6538077|ensemblmetazoa:Y48G8AL.10a.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:v6ckc3_caeel(display_long)|uniprotkb:znf-236(gene name)|psi-mi:znf-236(display_short)|uniprotkb:CELE_Y48G8AL.10(orf name)|uniprotkb:Y48G8AL.10(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540702|imex:IM-18681-660 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-111367|reactome:R-CEL-73856|reactome:R-CEL-77588|ensemblmetazoa:WBGene00021689(gene)|ensemblmetazoa:Y48G8AL.10a.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_001293225.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|wormbase:Y48G8AL.10a|interpro:IPR036236|uniprotkb:Q9BL20(identity)|wormbase:WBGene00021689(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:untbXZe0VJLK0UhnM5vZA+ORfyU6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:DF6FE3660508B833|rigid:8REszQm+mQj8Dtckeq3zwzz+oYg false - sufficient binding region:252-309 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:X5M5N0 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-6540721|intact:EBI-7713269|intact:UNK-5972656|uniprotkb:H2L282|uniprotkb:H2L283|uniprotkb:H2L284|uniprotkb:H2L285|uniprotkb:H2L286|uniprotkb:H2L288|uniprotkb:H2L289|uniprotkb:H2L290|uniprotkb:H2L291|uniprotkb:H2L292|uniprotkb:H2L293|uniprotkb:Q18657|uniprotkb:Q8I127|uniprotkb:X5LPT1|uniprotkb:X5LPT5|uniprotkb:X5LV40|uniprotkb:X5LV44|uniprotkb:X5LX64|uniprotkb:X5M5N6|uniprotkb:X5M8T1|uniprotkb:X5M8T5|ensemblmetazoa:C46C2.1n.1|ensemblmetazoa:C46C2.1n.2 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:wnk_caeel(display_long)|uniprotkb:Protein kinase with no lysine 1(gene name synonym)|uniprotkb:C46C2.1(orf name)|uniprotkb:wnk-1(gene name)|psi-mi:wnk-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540717|imex:IM-18681-661 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) wormbase:C46C2.1b|wormbase:C46C2.1c|wormbase:C46C2.1d|wormbase:C46C2.1e|wormbase:C46C2.1f|wormbase:C46C2.1g|wormbase:C46C2.1h|wormbase:C46C2.1i|wormbase:C46C2.1j|wormbase:C46C2.1k|wormbase:C46C2.1l|wormbase:C46C2.1m|wormbase:C46C2.1n|wormbase:C46C2.1o|wormbase:C46C2.1p|wormbase:C46C2.1q|wormbase:C46C2.1r|wormbase:C46C2.1s|wormbase:C46C2.1t|wormbase:C46C2.1u|wormbase:C46C2.1v|ensemblmetazoa:C46C2.1n.1(transcript)|ensemblmetazoa:C46C2.1n.2(transcript)|ensemblmetazoa:WBGene00006941(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050801"(ion homeostasis)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|reactome:R-CEL-2672351|refseq:NP_001255367.1|refseq:NP_001255368.1|refseq:NP_001255369.1|refseq:NP_001255370.1|refseq:NP_001255371.1|refseq:NP_001255372.1|refseq:NP_001255373.1|refseq:NP_001255374.1|refseq:NP_001255375.1|refseq:NP_001255376.1|refseq:NP_001255377.1|refseq:NP_001294032.1|refseq:NP_001294033.1|refseq:NP_001294034.1|refseq:NP_001294035.1|refseq:NP_001294036.1|refseq:NP_001294037.1|refseq:NP_001294038.1|refseq:NP_001294039.1|refseq:NP_001294040.1|refseq:NP_501603.3|refseq:NP_872075.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|wormbase:C46C2.1a|mint:X5M5N0|uniprotkb:Q18657(identity)|wormbase:WBGene00006941(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/07/18 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:H7Hnb9aFa8HucS/PFDKM0vcW8vA6239 intact-crc:A0BD47052FB4AD78|rigid:sfrVifPvOvsny8FC+48Z408Ps20 false sufficient binding region:1464-1523 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q19782 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-320224|ensemblmetazoa:F25E2.4.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:ifd2_caeel(display_long)|uniprotkb:ifd-2(gene name)|psi-mi:ifd-2(display_short)|uniprotkb:F25E2.4(orf name)|uniprotkb:Intermediate filament protein D2(gene name synonym)|uniprotkb:Cel IF D2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540734|imex:IM-18681-662 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_508160.1|wormbase:F25E2.4|ensemblmetazoa:F25E2.4.1(transcript)|ensemblmetazoa:WBGene00002058(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-24353N|uniprotkb:Q19782(identity)|wormbase:WBGene00002058(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:88VvVnae9HlEVXvOcl3pryPLe5g6239 intact-crc:E1BABECF64C6B153|rigid:w5I/xctrgOeGTwROFajf6VD4CSI false sufficient binding region:1464-1523 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20010 uniprotkb:G5ECK4 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540749|imex:IM-18681-663 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N|uniprotkb:Q20010(identity)|wormbase:WBGene00009385(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 86|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:DE66017C24DC3B66|rigid:ux0Oq845Ssj8EPlozpMVZi0dXx0 false - sufficient binding region:1464-1523 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q9XTY6 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-495781|uniprotkb:Q9BKB5|uniprotkb:Q9XTY4|ensemblmetazoa:T03D8.1a.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:numb1_caeel(display_long)|uniprotkb:Protein kinase C adapter 1(gene name synonym)|uniprotkb:CKA1(gene name synonym)|uniprotkb:num-1(gene name)|psi-mi:num-1(display_short)|uniprotkb:cka-1(gene name synonym)|uniprotkb:T03D8.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540764|imex:IM-18681-664 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_001024097.1|refseq:NP_001024098.1|refseq:NP_508021.1|wormbase:T03D8.1a|wormbase:T03D8.1b|wormbase:T03D8.1c|interpro:IPR016698(Numb/numb-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|reactome:R-CEL-437239|reactome:R-CEL-5610780|reactome:R-CEL-5632684|ensemblmetazoa:T03D8.1a.1(transcript)|ensemblmetazoa:WBGene00003830(gene)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0051117"(ATPase binding)|uniprotkb:Q9XTY6(identity)|wormbase:WBGene00003830(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 32|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:qO+DFvMBt2DE+ZS7l8axk5DMOFQ6239 intact-crc:991BB9105AF1545D|rigid:MVLUBRkYaZBHKjmUB54YiyOodJs false sufficient binding region:1464-1523 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q9BI71 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-313770|ensemblmetazoa:T04C10.2b.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q9bi71_caeel(display_long)|uniprotkb:epn-1(gene name)|psi-mi:epn-1(display_short)|uniprotkb:CELE_T04C10.2(orf name)|uniprotkb:T04C10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540779|imex:IM-18681-665 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_510458.1|wormbase:T04C10.2b|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR003903(Ubiquitin interacting motif)|ensemblmetazoa:T04C10.2b.1(transcript)|ensemblmetazoa:WBGene00001329(gene)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032009"(early phagosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|interpro:IPR027318|uniprotkb:Q9BI71(identity)|wormbase:WBGene00001329(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 15|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:Aw70F0klLj4qD37NLNN8fD54oz06239 intact-crc:6D1333D834646853|rigid:VPcy+Rbi04RQKh04+O44zmG6qSg false sufficient binding region:1464-1523 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39055 uniprotkb:Q45FX5 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540809|imex:IM-18681-667 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 intact-crc:6703A360BED3260D|rigid:oJchLV9TCDtb4VSpC1QzjXvjUvQ false - sufficient binding region:620-676 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q95Y26 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-2316437|ensemblmetazoa:Y41D4A.5.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q95y26_caeel(display_long)|uniprotkb:ptpn-22(gene name)|psi-mi:ptpn-22(display_short)|uniprotkb:CELE_Y41D4A.5(orf name)|uniprotkb:Y41D4A.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540794|imex:IM-18681-666 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_500128.2|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|wormbase:Y41D4A.5|interpro:IPR029021|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|reactome:R-CEL-388844|ensemblmetazoa:WBGene00021507(gene)|ensemblmetazoa:Y41D4A.5.1(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008045"(motor neuron axon guidance)|uniprotkb:Q95Y26(identity)|wormbase:WBGene00021507(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:sXWy7Nr8zlq7TXysWGI7SNNBjeM6239 intact-crc:879402F668BFC19B|rigid:FdBQCzKMMrgZZFh36ferxncQj1E false sufficient binding region:1464-1523 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19905 uniprotkb:Q45FX5 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540824|imex:IM-18681-668 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N|uniprotkb:Q19905(identity)|wormbase:WBGene00005022(identity) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 intact-crc:B2640E4376563312|rigid:UnvRWiYYZvmPRn2Dyyg1RPBjPuw false - sufficient binding region:620-676 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55956 uniprotkb:Q45FX5 intact:EBI-313689|uniprotkb:Q9TXI5|ensemblmetazoa:H22K11.1.1 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 psi-mi:asp3_caeel(display_long)|uniprotkb:asp-3(gene name)|psi-mi:asp-3(display_short)|uniprotkb:H22K11.1(orf name) psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540839|imex:IM-18681-669 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-5683826|reactome:R-CEL-2022377|wormbase:H22K11.1|refseq:NP_509142.2|ensemblmetazoa:H22K11.1.1(transcript)|ensemblmetazoa:WBGene00000216(gene)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0008219"(cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0070265"(necrotic cell death)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR021109|interpro:IPR033121|reactome:R-CEL-2132295|dip:DIP-26574N|uniprotkb:P55956(identity)|wormbase:WBGene00000216(identity) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:3di+vT8IFrs/9rmcA2d0BOi1ZZQ6239 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 intact-crc:F03780AAD6308A48|rigid:zZYxszm2xhG/FHdD3PHAdX78LCs false - sufficient binding region:620-676 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:G5ECL2 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-6532216|uniprotkb:B3CJ53|uniprotkb:G5EDR8|uniprotkb:G5EEJ9|ensemblmetazoa:JC8.10b.1 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:synj_caeel(display_long)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Uncoordinated protein 26(gene name synonym)|uniprotkb:JC8.10(orf name)|uniprotkb:unc-26(gene name)|psi-mi:unc-26(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540854|imex:IM-18681-670 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR015047(Region of unknown function DUF1866)|reactome:R-CEL-8856828|refseq:NP_001023265.1|refseq:NP_001023266.1|refseq:NP_001122785.1|wormbase:JC8.10a|wormbase:JC8.10b|wormbase:JC8.10c|ensemblmetazoa:JC8.10b.1(transcript)|ensemblmetazoa:WBGene00006763(gene)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0006936"(muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043059"(regulation of forward locomotion)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048212"(Golgi vesicle uncoating)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|reactome:R-CEL-1660499|reactome:R-CEL-1855183|reactome:R-CEL-1855204|interpro:IPR002013(Synaptojanin, N-terminal)|refseq:NP_001129862.1|wormbase:JC8.10d|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR036691|uniprotkb:B3CJ53(identity)|wormbase:WBGene00006763(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 32|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:pgekh+yDW79IwpRxK6q2GMEDteg6239 intact-crc:78E652FE1D2C90C9|rigid:nZSKAiS+vz9AdcHtjjr/cbeMb/U false sufficient binding region:620-676 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:G5EE04 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-896154|ensemblmetazoa:T12D8.8.1|ensemblmetazoa:T12D8.8.2 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:g5ee04_caeel(display_long)|uniprotkb:T12D8.8(orf name)|uniprotkb:hip-1(gene name)|psi-mi:hip-1(display_short)|uniprotkb:CELE_T12D8.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540869|imex:IM-18681-671 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) reactome:R-CEL-3371453|uniprotkb:O45786(uniprot-removed-ac)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:NP_499811.1|interpro:IPR034649|wormbase:T12D8.8|interpro:IPR041243|ensemblmetazoa:T12D8.8.1(transcript)|ensemblmetazoa:T12D8.8.2(transcript)|ensemblmetazoa:WBGene00011735(gene)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030017"(sarcomere)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0065003"(protein-containing complex assembly)|uniprotkb:G5EE04(identity)|wormbase:WBGene00011735(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:FxNGPNqdfNwYyRSe/i9ru5HnyjY6239 intact-crc:222D6C1374645A01|rigid:wYv0l83xchL0ZtzskziX7wq0sJA false sufficient binding region:620-676 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDG6 uniprotkb:Q45FX5 intact:EBI-318567|ensemblmetazoa:T28C6.4.1|ensemblmetazoa:T28C6.6.1 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 psi-mi:g5edg6_caeel(display_long)|uniprotkb:col-117(gene name)|psi-mi:col-117(display_short)|uniprotkb:col-3(gene name synonym)|uniprotkb:4J588(orf name)|uniprotkb:4J589(orf name)|uniprotkb:CELE_T28C6.4(orf name)|uniprotkb:CELE_T28C6.6(orf name)|uniprotkb:T28C6.4(orf name)|uniprotkb:T28C6.6(orf name) psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540884|imex:IM-18681-672 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q27318(uniprot-removed-ac)|interpro:IPR002486(Nematode cuticle collagen, N-terminal)|interpro:IPR008160(Collagen triple helix repeat)|refseq:NP_501526.1|refseq:NP_501527.1|wormbase:T28C6.4|wormbase:T28C6.6|go:"GO:0016021"(integral component of membrane)|go:"GO:0042302"(structural constituent of cuticle)|go:"GO:0005581"(collagen trimer)|ensemblmetazoa:T28C6.4.1(transcript)|ensemblmetazoa:T28C6.6.1(transcript)|ensemblmetazoa:WBGene00000594(gene)|ensemblmetazoa:WBGene00000691(gene)|uniprotkb:G5EDG6(identity)|wormbase:WBGene00000691(identity) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Ol74OFLhRmunXjvssV3MyqHaQDc6239 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 intact-crc:D604850DA55F197A|rigid:TW8YGejhLNv9dkZe8asgeiNV64s false - sufficient binding region:620-676 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:V6CKC3 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-6538077|ensemblmetazoa:Y48G8AL.10a.1 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:v6ckc3_caeel(display_long)|uniprotkb:znf-236(gene name)|psi-mi:znf-236(display_short)|uniprotkb:CELE_Y48G8AL.10(orf name)|uniprotkb:Y48G8AL.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540899|imex:IM-18681-673 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) reactome:R-CEL-111367|reactome:R-CEL-73856|reactome:R-CEL-77588|ensemblmetazoa:WBGene00021689(gene)|ensemblmetazoa:Y48G8AL.10a.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_001293225.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|wormbase:Y48G8AL.10a|interpro:IPR036236|uniprotkb:Q9BL20(identity)|wormbase:WBGene00021689(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:untbXZe0VJLK0UhnM5vZA+ORfyU6239 intact-crc:B328C5324D478FBA|rigid:hAEtS+qSLzfq+edd7AeKkHOqsrc false sufficient binding region:620-676 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBZ8 uniprotkb:Q6A573 intact:EBI-6532845|ensemblmetazoa:C01C7.1a.1|uniprotkb:C6KRP0 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:ark1_caeel(display_long)|uniprotkb:ark-1(gene name)|psi-mi:ark-1(display_short)|uniprotkb:Ras-regulating kinase ark-1(gene name synonym)|uniprotkb:C01C7.1(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540914|imex:IM-18681-674 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C01C7.1a.1(transcript)|ensemblmetazoa:WBGene00000186(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_001255653.1|refseq:NP_001255654.1|wormbase:C01C7.1a|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|wormbase:C01C7.1b|interpro:IPR036028|uniprotkb:C6KRP0(identity)|wormbase:WBGene00000186(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/09/24 rogid:3y4DKCGtK0UAmuo7wGZIoULkmis6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:166BEBF070A2474E|rigid:1Zh2pVPJp4zkt8txTVx1cwb7SKo false - sufficient binding region:49-106 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6A573 uniprotkb:A5JYT2 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 intact:EBI-2915506|ensemblmetazoa:C01H6.7b.1|ensemblmetazoa:C01H6.7b.2 psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:a5jyt2_caeel(display_long)|uniprotkb:swsn-9(gene name)|psi-mi:swsn-9(display_short)|uniprotkb:C01H6.7(orf name)|uniprotkb:CELE_C01H6.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540929|imex:IM-18681-675 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) ensemblmetazoa:C01H6.7b.1(transcript)|ensemblmetazoa:C01H6.7b.2(transcript)|ensemblmetazoa:WBGene00007256(gene)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR021900|refseq:NP_001122414.1|wormbase:C01H6.7b|interpro:IPR036427|uniprotkb:A5JYT2(identity)|wormbase:WBGene00007256(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 213|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 rogid:NIbg+K7XjZYxaPiVFKQReT8j6vE6239 intact-crc:0D93C12C2BCBC90B|rigid:CuY79Vxz0p+HeLeE1u4M+BvhM1U false sufficient binding region:49-106 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6A573 uniprotkb:Q8I4M6 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 intact:EBI-6536576|ensemblmetazoa:C31C9.6.1 psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:q8i4m6_caeel(display_long)|uniprotkb:CELE_C31C9.6(orf name)|uniprotkb:C31C9.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540944|imex:IM-18681-676 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) ensemblmetazoa:C31C9.6.1(transcript)|ensemblmetazoa:WBGene00007840(gene)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_872049.2|wormbase:C31C9.6|uniprotkb:Q8I4M6(identity)|wormbase:WBGene00007840(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 rogid:huZLaHG/E3MLyCCJa5FNBcjs4RQ6239 intact-crc:F267BD73190DF2E1|rigid:Nw+uEzOf4yOcXm2MP3PjyAAQUOE false sufficient binding region:49-106 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19275 uniprotkb:Q6A573 intact:EBI-315168|ensemblmetazoa:F09F7.5a.1|ensemblmetazoa:F09F7.5a.2|ensemblmetazoa:F09F7.5a.3 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:q19275_caeel(display_long)|uniprotkb:CELE_F09F7.5(orf name)|uniprotkb:F09F7.5(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540959|imex:IM-18681-677 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498186.1|wormbase:F09F7.5a|go:"GO:0005886"(plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035023"(regulation of Rho protein signal transduction)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR036936|interpro:IPR039056|ensemblmetazoa:WBGene00017302(gene)|ensemblmetazoa:F09F7.5a.1(transcript)|ensemblmetazoa:F09F7.5a.2(transcript)|ensemblmetazoa:F09F7.5a.3(transcript)|dip:DIP-25885N|uniprotkb:Q19275(identity)|wormbase:WBGene00017302(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:dRcTzChc6E57GiyrC46iYMLP5Tg6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:AA5CA29ADF6720F0|rigid:m0rP4IlLEfj9S2aYLBqcEGe2WZI false - sufficient binding region:49-106 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6A573 uniprotkb:P34397 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 intact:EBI-321990|ensemblmetazoa:F10E9.3.1 psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:ylu3_caeel(display_long)|uniprotkb:F10E9.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540974|imex:IM-18681-678 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) refseq:NP_498826.2|wormbase:F10E9.3|ensemblmetazoa:F10E9.3.1(transcript)|ensemblmetazoa:WBGene00017355(gene)|interpro:IPR040437|dip:DIP-26529N|uniprotkb:P34397(identity)|wormbase:WBGene00017355(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 rogid:rI7gLX2TWTqguT53dk5CTySk7to6239 intact-crc:D503547A32486FCA|rigid:7NsCEdwD9irNAnU18lv5/w78O+U false sufficient binding region:49-106 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62256 uniprotkb:Q6A573 intact:EBI-315395|ensemblmetazoa:F52G2.3.1 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:o62256_caeel(display_long)|uniprotkb:F52G2.3(orf name)|uniprotkb:CELE_F52G2.3(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6540989|imex:IM-18681-679 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011508(RSD-2, N-terminal)|refseq:NP_502611.2|wormbase:F52G2.3|ensemblmetazoa:F52G2.3.1(transcript)|ensemblmetazoa:WBGene00009943(gene)|uniprotkb:O62256(identity)|wormbase:WBGene00009943(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:N/pFT/+MuQCA9qBRhFIHNnrWUpk6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:9E3012D42C151B32|rigid:XjA6ocMzpd13axG3qplJkcsV8Ck false - sufficient binding region:49-106 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6A573 uniprotkb:Q8ITV6 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 intact:EBI-319717|ensemblmetazoa:Y44E3A.6b.1|ensemblmetazoa:Y44E3A.6b.2 psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:q8itv6_caeel(display_long)|uniprotkb:edc-4(gene name)|psi-mi:edc-4(display_short)|uniprotkb:CELE_Y44E3A.6(orf name)|uniprotkb:Y44E3A.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541004|imex:IM-18681-680 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) refseq:NP_740828.1|wormbase:Y44E3A.6b|interpro:IPR000253(Forkhead-associated)|ensemblmetazoa:WBGene00021551(gene)|ensemblmetazoa:Y44E3A.6b.1(transcript)|ensemblmetazoa:Y44E3A.6b.2(transcript)|go:"GO:0000932"(P-body)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|reactome:R-CEL-430039|interpro:IPR032401|uniprotkb:Q8ITV6(identity)|wormbase:WBGene00021551(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 rogid:AmO3iQKS9B88Xq2SgMlDJE4JCfs6239 intact-crc:6DCCD91AD72BDBD1|rigid:PQ+cRu7Zm/kzlTNZUNEet8CQOo8 false sufficient binding region:49-106 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23419 uniprotkb:Q6A573 intact:EBI-328005|ensemblmetazoa:ZK1248.10.1|ensemblmetazoa:ZK1248.10.2 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:q23419_caeel(display_long)|uniprotkb:tbc-2(gene name)|psi-mi:tbc-2(display_short)|uniprotkb:CELE_ZK1248.10(orf name)|uniprotkb:ZK1248.10(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541019|imex:IM-18681-681 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495156.1|wormbase:ZK1248.10|ensemblmetazoa:WBGene00022880(gene)|ensemblmetazoa:ZK1248.10.1(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005770"(late endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035969|ensemblmetazoa:ZK1248.10.2(transcript)|dip:DIP-26274N|reactome:R-CEL-432722|uniprotkb:Q23419(identity)|wormbase:WBGene00022880(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:0jbTu1E3m9G4by9ArOJRfoq0JDo6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:03EF3CB7C8A8B308|rigid:9SjUB9G163hkuE/yie1yMWRpF50 false - sufficient binding region:49-106 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18100 uniprotkb:Q6A573 intact:EBI-6541038|ensemblmetazoa:C18F3.2a.1 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:q18100_caeel(display_long)|uniprotkb:C18F3.2(orf name)|uniprotkb:sax-7(gene name)|psi-mi:sax-7(display_short)|uniprotkb:CELE_C18F3.2(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541034|imex:IM-18681-682 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C18F3.2a.1(transcript)|ensemblmetazoa:WBGene00004732(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0003384"(apical constriction involved in gastrulation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030017"(sarcomere)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0050839"(cell adhesion molecule binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026966|refseq:NP_001033394.1|wormbase:C18F3.2a|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR036116|interpro:IPR036179|uniprotkb:Q18100(identity)|wormbase:WBGene00004732(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:11uwq48ryS/UtrhT1QizYRF1ruY6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:56F130672FDB5EFA|rigid:Z3nlJ30Qb+CwYPlglU6AUspLQfk false - sufficient binding region:193-251 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43510 uniprotkb:Q6A573 intact:EBI-315774|ensemblmetazoa:C25B8.3a.1 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:cpr6_caeel(display_long)|uniprotkb:cpr-6(gene name)|psi-mi:cpr-6(display_short)|uniprotkb:C25B8.3(orf name)|uniprotkb:Cysteine protease-related 6(gene name synonym) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541051|imex:IM-18681-683 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741818.1|ensemblmetazoa:C25B8.3a.1(transcript)|ensemblmetazoa:WBGene00000786(gene)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|dip:DIP-25139N|reactome:R-CEL-1442490|reactome:R-CEL-2132295|reactome:R-CEL-6798695|wormbase:C25B8.3|uniprotkb:P43510(identity)|wormbase:WBGene00000786(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BotUl3VttQEi9EL1FNNgyssNCDo6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:194AC475D17E0F95|rigid:VkmUDYguR0tBoJS9M01+/zXyz5Y false - sufficient binding region:193-251 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q965H3 uniprotkb:Q6A573 intact:EBI-331594|uniprotkb:A3QMA2|ensemblmetazoa:C50E10.4a.1 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:sop2_caeel(display_long)|uniprotkb:C50E10.4(orf name)|uniprotkb:sop-2(gene name)|psi-mi:sop-2(display_short)|uniprotkb:Suppressor of pal-1 protein 2(gene name synonym) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541066|imex:IM-18681-684 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001254341.1|wormbase:C50E10.4a|dip:DIP-25161N|ensemblmetazoa:C50E10.4a.1(transcript)|ensemblmetazoa:WBGene00004945(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003723"(RNA binding)|go:"GO:0006325"(chromatin organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007411"(axon guidance)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048665"(neuron fate specification)|uniprotkb:Q965H3(identity)|wormbase:WBGene00004945(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:FxOJOnmRFYA40lqbgaAmfMBwbCw6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:AA4D8581BFDC2261|rigid:E6XX+xuEDO83xcTxqyjCyhWjbwU false - sufficient binding region:193-251 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6A573 uniprotkb:P53013 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 intact:EBI-314893|ensemblmetazoa:F31E3.5.1|ensemblmetazoa:F31E3.5.2|ensemblmetazoa:F31E3.5.3|ensemblmetazoa:R03G5.1a.1|ensemblmetazoa:R03G5.1a.2|ensemblmetazoa:R03G5.1a.3|ensemblmetazoa:R03G5.1a.4 psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:ef1a_caeel(display_long)|uniprotkb:eft-3(gene name)|psi-mi:eft-3(display_short)|uniprotkb:F31E3.5(orf name)|uniprotkb:R03G5.1(orf name)|uniprotkb:eft-4(gene name)|psi-mi:eft-4(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541096|imex:IM-18681-686 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) refseq:NP_498520.1|refseq:NP_509323.1|wormbase:F31E3.5|wormbase:R03G5.1a|ensemblmetazoa:F31E3.5.1(transcript)|ensemblmetazoa:F31E3.5.2(transcript)|ensemblmetazoa:F31E3.5.3(transcript)|ensemblmetazoa:R03G5.1a.1(transcript)|ensemblmetazoa:R03G5.1a.2(transcript)|ensemblmetazoa:R03G5.1a.3(transcript)|ensemblmetazoa:R03G5.1a.4(transcript)|ensemblmetazoa:WBGene00001168(gene)|ensemblmetazoa:WBGene00001169(gene)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|dip:DIP-26595N|reactome:R-CEL-3371511|reactome:R-CEL-6798695|reactome:R-CEL-8876725|uniprotkb:P53013(identity)|wormbase:WBGene00001168(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 rogid:jphYYhCA/nRB2xXz+s9+kwn43oc6239 intact-crc:DD65DD9C353025B9|rigid:Wrau4UBBfNLTPj64XRTRa8leOas false sufficient binding region:193-251 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6A573 uniprotkb:E3W743 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541081|imex:IM-18681-685 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 intact-crc:7797B6FD6F82C7D7|rigid:T0PBALruw9gih99Wt8kObomSPuU false sufficient binding region:193-251 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20950 uniprotkb:Q6A573 intact:EBI-312868|ensemblmetazoa:F57F5.1.1 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:q20950_caeel(display_long)|uniprotkb:cpr-9(gene name)|psi-mi:cpr-9(display_short)|uniprotkb:CELE_F57F5.1(orf name)|uniprotkb:F57F5.1(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541111|imex:IM-18681-687 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506011.2|wormbase:F57F5.1|ensemblmetazoa:F57F5.1.1(transcript)|ensemblmetazoa:WBGene00010204(gene)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|dip:DIP-24447N|uniprotkb:Q20950(identity)|wormbase:WBGene00010204(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:8sXE02/TDt7bidRsEagvVGJS3eE6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:4D88310F8E3CC946|rigid:DNeB+y+MjEifI2clp7h0D/hvl9k false - sufficient binding region:193-251 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1ZXS5 uniprotkb:Q6A573 intact:EBI-318975|uniprotkb:Q9XUQ4|uniprotkb:A8JJR1|ensemblmetazoa:T08G5.5b.1|intact:EBI-14973910|intact:EBI-6534008 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:vps39_caeel(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541126|imex:IM-18681-688 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041163.1|wormbase:T08G5.5a|refseq:NP_001041164.1|refseq:NP_001123010.1|wormbase:T08G5.5b|wormbase:T08G5.5c|ensemblmetazoa:T08G5.5b.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|interpro:IPR001180(Citron-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019452|interpro:IPR019453|interpro:IPR032914|interpro:IPR036322|dip:DIP-24817N|uniprotkb:A8JJR1(identity)|wormbase:WBGene00011625(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2017/10/20 rogid:OY+zb1zby7cfHD+BQwKt56yw7HY6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:2827D6483CDFAB80|rigid:C/qj9oc2g9b/VL51dfEbh3NhSsE false - sufficient binding region:193-251 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6533373 uniprotkb:Q6A573 - intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:g3mu69_caeel(display_short)|psi-mi:EBI-6533373(display_long)|uniprotkb:T27E9.1(orf name)|uniprotkb:ant-1.1(gene name)|psi-mi:ant-1.1(display_short)|uniprotkb:CELE_T27E9.1(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541141|imex:IM-18681-689 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:G3MU69(uniprot-removed-ac)|uniprotkb:G3MU69(identity)|wormbase:WBGene00006439(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:haVkJWSnhAa5irdfMD7lj2O3KY46239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:C49A13D68C07D904|rigid:4Mvd3WTWuVbKfii6Ar70mFZvGis false - sufficient binding region:193-251 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:D0IMZ5 uniprotkb:Q6A573 intact:EBI-6534036|ensemblmetazoa:Y66H1B.2a.1 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:d0imz5_caeel(display_long)|uniprotkb:Y66H1B.2(orf name)|uniprotkb:fln-1(gene name)|psi-mi:fln-1(display_short)|uniprotkb:CELE_Y66H1B.2(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541156|imex:IM-18681-690 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00022048(gene)|ensemblmetazoa:Y66H1B.2a.1(transcript)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0061038"(uterus morphogenesis)|interpro:IPR044801|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|refseq:NP_001023550.2|wormbase:Y66H1B.2a|interpro:IPR036872|uniprotkb:D0IMZ5(identity)|wormbase:WBGene00022048(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 75|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:9hCmcqWxWSY2QYeg05bDz4qoY/U6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:9656C15F2BB55070|rigid:df+TJ6FndfDuBLgktG+uLNMjavk false - sufficient binding region:193-251 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2D6 uniprotkb:Q17865 intact:EBI-329790|ensemblmetazoa:Y46G5A.10.1 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:cnp2_caeel(display_long)|uniprotkb:cnp-2(gene name)|psi-mi:cnp-2(display_short)|uniprotkb:Calcineurin binding protein 2(gene name synonym)|uniprotkb:Y46G5A.10(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541174|imex:IM-18681-691 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496715.3|wormbase:Y46G5A.10|dip:DIP-26531N|ensemblmetazoa:WBGene00012901(gene)|ensemblmetazoa:Y46G5A.10.1(transcript)|reactome:R-CEL-5621480|reactome:R-CEL-913709|uniprotkb:Q9U2D6(identity)|wormbase:WBGene00012901(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:c283678sLaAPqMx0BPNxcEYLzhE6239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:C9D09C5F112D4743|rigid:4b2WajvfjLpIDlvp154HlSkM6xc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G8JYB2 uniprotkb:P39055 intact:EBI-6530722|ensemblmetazoa:Y23H5A.5d.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:g8jyb2_caeel(display_long)|uniprotkb:Y23H5A.5(orf name)|uniprotkb:ctn-1(gene name)|psi-mi:ctn-1(display_short)|uniprotkb:CELE_Y23H5A.5(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541187|imex:IM-18681-692 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030045|ensemblmetazoa:WBGene00000832(gene)|ensemblmetazoa:Y23H5A.5d.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|refseq:NP_740813.2|wormbase:Y23H5A.5d|interpro:IPR036723|uniprotkb:G8JYB2(identity)|wormbase:WBGene00000832(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Vi3tH7mbD/nDGfvpd5acMGXv7Qw6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:4D2A22B73BD54C29|rigid:JiBwNbQH2qcg7RyWj8SFScHNI4Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21648 uniprotkb:G5ED33 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541200|imex:IM-18681-693 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:5C828C052A503EF6|rigid:VUZ8wG7uluCVoqY5ctvYzmKoV+g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02040 uniprotkb:Q1XFY2 intact:EBI-6541217|ensemblmetazoa:T23C6.4.1 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 psi-mi:o02040_caeel(display_long)|uniprotkb:CELE_T23C6.4(orf name)|uniprotkb:T23C6.4(orf name) psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541213|imex:IM-18681-694 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T23C6.4.1(transcript)|ensemblmetazoa:WBGene00020726(gene)|refseq:NP_510777.1|wormbase:T23C6.4|uniprotkb:O02040(identity)|wormbase:WBGene00020726(identity) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JPgeGEL69u0KNh382q3Q7/ygA286239 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 intact-crc:B2DBD09D0DFBED45|rigid:TlHLU5C4hJSbKKyaCTF3JtXio0M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1XFY2 uniprotkb:Q9N3J4 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 intact:EBI-6541232|ensemblmetazoa:Y51H7C.7.1 psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:q9n3j4_caeel(display_long)|uniprotkb:CELE_Y51H7C.7(orf name)|uniprotkb:Y51H7C.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541228|imex:IM-18681-695 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) ensemblmetazoa:WBGene00021785(gene)|ensemblmetazoa:Y51H7C.7.1(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_493965.1|wormbase:Y51H7C.7|reactome:R-CEL-6791226|uniprotkb:Q9N3J4(identity)|wormbase:WBGene00021785(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 rogid:K5ZHzB7hRABgpIetrkEtyPsvBgM6239 intact-crc:6AD24B4CF5A85E0A|rigid:+FwEZzEWP4mNBsp5ljLsc8jn0cY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22463 uniprotkb:Q22387 intact:EBI-6531416|ensemblmetazoa:T13H2.5b.1 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 psi-mi:q22463_caeel(display_long)|uniprotkb:CELE_T13H2.5(orf name)|uniprotkb:spat-3(gene name)|psi-mi:spat-3(display_short)|uniprotkb:T13H2.5(orf name) psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541243|imex:IM-18681-696 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T13H2.5b.1(transcript)|ensemblmetazoa:WBGene00020496(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|refseq:NP_001024905.1|wormbase:T13H2.5b|interpro:IPR043540|uniprotkb:Q22463(identity)|wormbase:WBGene00020496(identity) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:OPfFXv1tgjbu1IQuLdxOB8/zDoM6239 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 intact-crc:F01CD0890CE363C3|rigid:WPMjIyLMzbFUqy9Aw3aYiwKXto4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22387 uniprotkb:Q9GYG1 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 intact:EBI-314846|ensemblmetazoa:ZC395.8.1 psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:q9gyg1_caeel(display_long)|uniprotkb:ztf-8(gene name)|psi-mi:ztf-8(display_short)|uniprotkb:CELE_ZC395.8(orf name)|uniprotkb:ZC395.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541256|imex:IM-18681-697 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) refseq:NP_498124.2|wormbase:ZC395.8|ensemblmetazoa:WBGene00022598(gene)|ensemblmetazoa:ZC395.8.1(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|dip:DIP-24679N|uniprotkb:Q9GYG1(identity)|wormbase:WBGene00022598(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 rogid:wsZC5q+nCfg+Qz99e0wmwQZxK4A6239 intact-crc:EA5DE6ED09A3BFE7|rigid:QdcnlRrLhXzhC3pOkkANJieSKSo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09651 uniprotkb:Q22387 intact:EBI-327687|ensemblmetazoa:ZK1307.9.1 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 psi-mi:cc130_caeel(display_long)|uniprotkb:ZK1307.9(orf name) psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541269|imex:IM-18681-698 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496077.1|wormbase:ZK1307.9|ensemblmetazoa:WBGene00014250(gene)|ensemblmetazoa:ZK1307.9.1(transcript)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR007590(Protein of unknown function DUF572)|dip:DIP-24831N|uniprotkb:Q09651(identity)|wormbase:WBGene00014250(identity) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JCJk2zdUQwefTU5cCEKDyCmseUI6239 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 intact-crc:A5C0C1CED1B20A61|rigid:AsaFbpdcGfXovGw7D1iK8dIUQ0w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23600 uniprotkb:Q22387 intact:EBI-6531431|ensemblmetazoa:ZK809.5a.1 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 psi-mi:q23600_caeel(display_long)|uniprotkb:CELE_ZK809.5(orf name)|uniprotkb:ZK809.5(orf name) psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541282|imex:IM-18681-699 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00014087(gene)|ensemblmetazoa:ZK809.5a.1(transcript)|refseq:NP_001023624.1|wormbase:ZK809.5a|uniprotkb:Q23600(identity)|wormbase:WBGene00014087(identity) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:hP1vMQ0F5lMHzWCF6SBDYUrhT6c6239 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 intact-crc:94E0378119AD5189|rigid:ntnLOxQISXL84E+r8h7k9TSkGaE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q11181 uniprotkb:G5EC72 intact:EBI-2316016|uniprotkb:Q8T3F3|uniprotkb:Q8T3F4|uniprotkb:Q8T3F5|ensemblmetazoa:C05D10.4b.1 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:ypc4_caeel(display_long)|uniprotkb:C05D10.4(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541295|imex:IM-18681-700 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498323.2|refseq:NP_498324.2|refseq:NP_741170.1|wormbase:C05D10.4a|wormbase:C05D10.4b|wormbase:C05D10.4c|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|ensemblmetazoa:C05D10.4b.1(transcript)|ensemblmetazoa:WBGene00015480(gene)|uniprotkb:Q11181(identity)|wormbase:WBGene00015480(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:msS16ZOpmue9+9+to7VFLPE1TM86239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:6962B9E88954129F|rigid:Rf/KGcUGG+6D6zhwlNyVoreIn+E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MNT0 uniprotkb:G5EC72 intact:EBI-324442|ensemblmetazoa:F28F5.3c.1 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:q8mnt0_caeel(display_long)|uniprotkb:lim-8(gene name)|psi-mi:lim-8(display_short)|uniprotkb:F28F5.3(orf name)|uniprotkb:CELE_F28F5.3(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541321|imex:IM-18681-702 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741201.1|wormbase:F28F5.3c|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|ensemblmetazoa:F28F5.3c.1(transcript)|ensemblmetazoa:WBGene00017904(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031430"(M band)|go:"GO:0032034"(myosin II head/neck binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|interpro:IPR036034|interpro:IPR041489|interpro:IPR029980|uniprotkb:Q8MNT0(identity)|wormbase:WBGene00017904(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Prm6YPAZkkBApz/l8EwwI2JDZvk6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:DF3F6F6C33B6EE8F|rigid:5trdRXnQiF7Ts7buGthVqqtT0dE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q95ZV9 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-327570|ensemblmetazoa:F08F8.9a.2|ensemblmetazoa:F08F8.9a.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:q95zv9_caeel(display_long)|uniprotkb:F08F8.9(orf name)|uniprotkb:CELE_F08F8.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541308|imex:IM-18681-701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) refseq:NP_498622.1|wormbase:F08F8.9a|ensemblmetazoa:F08F8.9a.2(transcript)|ensemblmetazoa:WBGene00017274(gene)|ensemblmetazoa:F08F8.9a.1(transcript)|dip:DIP-26979N|uniprotkb:Q95ZV9(identity)|wormbase:WBGene00017274(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:jwJXPQX/V2YFHWszVFrYOrcvLCU6239 intact-crc:C3214CC3944DFA31|rigid:cHQmn/d7JdH6PfuReegssA+WeNk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q966J7 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-6541338|ensemblmetazoa:F35B3.7.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:q966j7_caeel(display_long)|uniprotkb:CELE_F35B3.7(orf name)|uniprotkb:F35B3.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541334|imex:IM-18681-703 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) ensemblmetazoa:F35B3.7.1(transcript)|ensemblmetazoa:WBGene00018033(gene)|refseq:NP_510753.3|wormbase:F35B3.7|uniprotkb:Q966J7(identity)|wormbase:WBGene00018033(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:k9TztBvcEepeLTOn5BQYaAMPvSs6239 intact-crc:98FE990420078E33|rigid:zqvzauvpX6q7CP3PKzO46RN3FzY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22696 uniprotkb:G5EC72 intact:EBI-328387|ensemblmetazoa:T23F11.4.1 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:q22696_caeel(display_long)|uniprotkb:T23F11.4(orf name)|uniprotkb:CELE_T23F11.4(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541349|imex:IM-18681-704 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497952.1|wormbase:T23F11.4|dip:DIP-24429N|ensemblmetazoa:T23F11.4.1(transcript)|ensemblmetazoa:WBGene00011956(gene)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|uniprotkb:Q22696(identity)|wormbase:WBGene00011956(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:xAoxh4Urkwg45KvR1aP8C/nM9w86239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:7D989EEB35AF0BCE|rigid:xzYAip2XmuxfvbF+DWRNopnN3ts false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q4VNJ8 uniprotkb:G5EC72 intact:EBI-2918529 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541362|imex:IM-18681-705 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:757C092CA2FFE62A|rigid:uAEQ99lChafTuoVxWIcr6gvOpxw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q09651 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-327687|ensemblmetazoa:ZK1307.9.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:cc130_caeel(display_long)|uniprotkb:ZK1307.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541375|imex:IM-18681-706 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) refseq:NP_496077.1|wormbase:ZK1307.9|ensemblmetazoa:WBGene00014250(gene)|ensemblmetazoa:ZK1307.9.1(transcript)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR007590(Protein of unknown function DUF572)|dip:DIP-24831N|uniprotkb:Q09651(identity)|wormbase:WBGene00014250(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 20|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:JCJk2zdUQwefTU5cCEKDyCmseUI6239 intact-crc:54D1EC25125682F6|rigid:hIoeWPRsa7tljwL9xo4HAfYpfos false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:Q9U2D6 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-329790|ensemblmetazoa:Y46G5A.10.1 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:cnp2_caeel(display_long)|uniprotkb:cnp-2(gene name)|psi-mi:cnp-2(display_short)|uniprotkb:Calcineurin binding protein 2(gene name synonym)|uniprotkb:Y46G5A.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541388|imex:IM-18681-707 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) refseq:NP_496715.3|wormbase:Y46G5A.10|dip:DIP-26531N|ensemblmetazoa:WBGene00012901(gene)|ensemblmetazoa:Y46G5A.10.1(transcript)|reactome:R-CEL-5621480|reactome:R-CEL-913709|uniprotkb:Q9U2D6(identity)|wormbase:WBGene00012901(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:c283678sLaAPqMx0BPNxcEYLzhE6239 intact-crc:43D35578A874FB50|rigid:NVtmNKC/WULAnd1JHk6mwCHQhW0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16299 uniprotkb:P34258 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541401|imex:IM-18681-708 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 130|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 intact-crc:57C4A82F205D791C|rigid:32JGSdLSKDGh/tKt9mWlGfCxVAs false - sufficient binding region:194-251 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:O61761 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-2920917|ensemblmetazoa:F56C3.9.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:o61761_caeel(display_long)|uniprotkb:F56C3.9(orf name)|uniprotkb:CELE_F56C3.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541416|imex:IM-18681-709 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) ensemblmetazoa:F56C3.9.1(transcript)|ensemblmetazoa:WBGene00018946(gene)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_508258.1|wormbase:F56C3.9|interpro:IPR000210(BTB/POZ-like)|uniprotkb:O61761(identity)|wormbase:WBGene00018946(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:iorhNpl8YNyIRwuowLQemcSSG806239 intact-crc:FAD5917BBF08401F|rigid:L07kCBJCma7jpn8zeYg/WLzflnU false sufficient binding region:194-251 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:O76337 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-6532169|ensemblmetazoa:F56D2.7.1|uniprotkb:O01421 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:ced6_caeel(display_long)|uniprotkb:ced-6(gene name)|psi-mi:ced-6(display_short)|uniprotkb:Candidate adapter protein ced-6(gene name synonym)|uniprotkb:F56D2.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541431|imex:IM-18681-710 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) ensemblmetazoa:F56D2.7.1(transcript)|ensemblmetazoa:WBGene00000420(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012501"(programmed cell death)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0070986"(left/right axis specification)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|go:"GO:1904747"(positive regulation of apoptotic process involved in development)|go:"GO:0045335"(phagocytic vesicle)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_498203.2|wormbase:F56D2.7|uniprotkb:O76337(identity)|wormbase:WBGene00000420(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:VjlyH911QZCg4QZbyWiJu1i01cg6239 intact-crc:EB1189E338AABBB1|rigid:BMSLgYiILoxrCukIjW0NCXsl+/M false sufficient binding region:194-251 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17865 uniprotkb:P34258 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541446|imex:IM-18681-711 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 intact-crc:1182719DE7855747|rigid:AGIC5t83np17UjbxdmlQKxw58iw false - sufficient binding region:274-329 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45603 uniprotkb:P34258 intact:EBI-313357|ensemblmetazoa:H02I12.5.1 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 psi-mi:o45603_caeel(display_long)|uniprotkb:memi-3(gene name)|psi-mi:memi-3(display_short)|uniprotkb:CELE_H02I12.5(orf name)|uniprotkb:H02I12.5(orf name) psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541461|imex:IM-18681-712 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502151.1|wormbase:H02I12.5|ensemblmetazoa:H02I12.5.1(transcript)|ensemblmetazoa:WBGene00010353(gene)|dip:DIP-26445N|uniprotkb:O45603(identity)|wormbase:WBGene00010353(identity) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:6JI27ecswA6ONqSDNzvGxXYr52Y6239 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 intact-crc:418C416151810BB3|rigid:Q0Aq+bbtf8Gbw/5ZpA1qDF9Fgpk false - sufficient binding region:274-329 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10457 uniprotkb:P34258 intact:EBI-311886|ensemblmetazoa:B0286.3.1 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541476|imex:IM-18681-713 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 intact-crc:E14ECD31417FEA27|rigid:RvK988ZfQ323KMPfcUleph/daN4 false - sufficient binding region:358-413 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:H2KZZ2 uniprotkb:P34258 intact:EBI-2420815|intact:EBI-6765823|intact:EBI-6541491|uniprotkb:A0A2X0RWL7|uniprotkb:A0A2X0T4B7|uniprotkb:H2KZZ0|uniprotkb:H2KZZ1|uniprotkb:H2KZZ3|uniprotkb:H2KZZ4|uniprotkb:Q5TYL0|uniprotkb:Q86MJ3|uniprotkb:Q86MJ4|ensemblmetazoa:W02C12.3c.1 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 psi-mi:hlh30_caeel(display_long)|uniprotkb:hlh-30(gene name)|psi-mi:hlh-30(display_short)|uniprotkb:W02C12.3(orf name) psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541493|imex:IM-18681-714 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q95ZK5(uniprot-removed-ac)|reactome:R-CEL-3232118|refseq:NP_001023411.1|wormbase:W02C12.3a|wormbase:W02C12.3c|wormbase:W02C12.3d|wormbase:W02C12.3e|wormbase:W02C12.3f|wormbase:W02C12.3g|wormbase:W02C12.3h|wormbase:W02C12.3i|wormbase:W02C12.3j|interpro:IPR011598(Helix-loop-helix DNA-binding)|wormbase:W02C12.3b|interpro:IPR036638|refseq:NP_001023412.1|refseq:NP_001023413.1|refseq:NP_001023414.1|refseq:NP_001023415.1|refseq:NP_001023416.1|refseq:NP_500461.1|refseq:NP_500462.1|ensemblmetazoa:W02C12.3c.1(transcript)|ensemblmetazoa:WBGene00020930(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:1905686"(positive regulation of plasma membrane repair)|uniprotkb:Q5TYL0(identity)|wormbase:WBGene00020930(identity) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2021/02/11 rogid:iGZh0KT07VIYofGovWOZj0raCt06239 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 intact-crc:60406C4B512DB64F|rigid:40CHo+JlmzUfsUEcPhNMMSp8WgA false - sufficient binding region:358-413 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:Q9NA61 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541508|imex:IM-18681-715 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 intact-crc:55142E3DCEE4C8DA|rigid:tkmujPpnutHlASEcyDOtls3cX5o false sufficient binding region:358-413 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:G5EEQ3 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-319723|ensemblmetazoa:ZK1053.5.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:g5eeq3_caeel(display_long)|uniprotkb:scrm-2(gene name)|psi-mi:scrm-2(display_short)|uniprotkb:SCRM-2(gene name synonym)|uniprotkb:CELE_ZK1053.5(orf name)|uniprotkb:ZK1053.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541525|imex:IM-18681-716 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) uniprotkb:O18289(uniprot-removed-ac)|ensemblmetazoa:WBGene00014200(gene)|ensemblmetazoa:ZK1053.5.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017128"(phospholipid scramblase activity)|interpro:IPR005552(Scramblase)|refseq:NP_493321.1|interpro:IPR025659|wormbase:ZK1053.5|uniprotkb:G5EEQ3(identity)|wormbase:WBGene00014200(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:ayiWZFoWx+GH3NI47lKkWqbGlYY6239 intact-crc:4B2D039E3E6905A1|rigid:1+Lc5UwkqwzH32sIwSKh/Uy/4VA false sufficient binding region:358-413 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:P39055 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541540|imex:IM-18681-717 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:277E4C3F2C026562|rigid:KGIlbaGM1p6K/buAocDcDMtI8Wo false sufficient binding region:434-493 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:Q22387 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541555|imex:IM-18681-718 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 24|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 intact-crc:EC18489866C23FE7|rigid:Kosigz++1qeHm1+CWh26Umx3G5g false sufficient binding region:434-493 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QQ9 uniprotkb:Q10929 intact:EBI-2317344|ensemblmetazoa:C49H3.6a.1 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 psi-mi:q95qq9_caeel(display_long)|uniprotkb:C49H3.6(orf name)|uniprotkb:CELE_C49H3.6(orf name) psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541570|imex:IM-18681-719 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501316.2|wormbase:C49H3.6a|interpro:IPR019131|ensemblmetazoa:C49H3.6a.1(transcript)|ensemblmetazoa:WBGene00016792(gene)|go:"GO:0005737"(cytoplasm)|uniprotkb:Q95QQ9(identity)|wormbase:WBGene00016792(identity) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eHT6KUXkocreuSpbjuHpYT+s+tQ6239 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 intact-crc:8C82736C5053084D|rigid:G6m4kc479pXFffBcAe51oTYPmqI false - sufficient binding region:415-469 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:P34400 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-2315872|uniprotkb:P34386|uniprotkb:P34403|uniprotkb:Q7JQ80|uniprotkb:Q8WT53|ensemblmetazoa:F10E9.6c.1|ensemblmetazoa:F10E9.6c.2 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:mig10_caeel(display_long)|uniprotkb:mig-10(gene name)|psi-mi:mig-10(display_short)|uniprotkb:F10E9.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541585|imex:IM-18681-720 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) refseq:NP_001021248.1|refseq:NP_498821.2|refseq:NP_498822.2|wormbase:F10E9.6a|wormbase:F10E9.6b|wormbase:F10E9.6c|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000159(Ras-association)|interpro:IPR029071|reactome:R-CEL-354192|interpro:IPR039664|interpro:IPR039665|reactome:R-CEL-354194|reactome:R-CEL-5674135|ensemblmetazoa:F10E9.6c.1(transcript)|ensemblmetazoa:F10E9.6c.2(transcript)|ensemblmetazoa:WBGene00003243(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0007165"(signal transduction)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018991"(oviposition)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031941"(filamentous actin)|go:"GO:0032584"(growth cone membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0043204"(perikaryon)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099523"(presynaptic cytosol)|uniprotkb:P34400(identity)|wormbase:WBGene00003243(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:qni0Ph9hE7m4FAxHa2yRYfjO0qY6239 intact-crc:86F7C19FBB307812|rigid:sGHrRol5Jaj0wKlr/fXcfJO/YEw false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:O62203 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-320780|ensemblmetazoa:F32B4.4a.1|intact:EBI-6530763|uniprotkb:F5GUF6|uniprotkb:Q7Z0X2 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:phm2_caeel(display_long)|uniprotkb:phm-2(gene name)|psi-mi:phm-2(display_short)|uniprotkb:F32B4.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541600|imex:IM-18681-721 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) wormbase:F32B4.4a|ensemblmetazoa:F32B4.4a.1(transcript)|ensemblmetazoa:WBGene00009314(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007586"(digestion)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036361|refseq:NP_001021441.1|refseq:NP_001251667.1|refseq:NP_001021440.2|dip:DIP-25849N|reactome:R-CEL-3899300|wormbase:F32B4.4b|wormbase:F32B4.4c|uniprotkb:F5GUF6(identity)|wormbase:WBGene00009314(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/03/02 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:69Kg/RUbe1gThWpe8yrWyt9o0bQ6239 intact-crc:443FCE7CA8E13034|rigid:wI5oIK6VCsTjdra3yDcAI7kkrIU false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:Q966J6 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-327612|ensemblmetazoa:F41B4.1.1 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:q966j6_caeel(display_long)|uniprotkb:F41B4.1(orf name)|uniprotkb:CELE_F41B4.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541615|imex:IM-18681-722 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) refseq:NP_509148.2|wormbase:F41B4.1|ensemblmetazoa:F41B4.1.1(transcript)|ensemblmetazoa:WBGene00018257(gene)|dip:DIP-26336N|uniprotkb:Q966J6(identity)|wormbase:WBGene00018257(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 40|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:daBFAeewQ1vhaxj4tlw0watbWpw6239 intact-crc:8B146D1EF83B3415|rigid:zBvjz+fr9wsrSljQsPapdNjhKrE false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:Q95Y95 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-2315841|ensemblmetazoa:M04F3.5b.1 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:q95y95_caeel(display_long)|uniprotkb:CELE_M04F3.5(orf name)|uniprotkb:M04F3.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541630|imex:IM-18681-723 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) refseq:NP_491448.2|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR030127|wormbase:M04F3.5b|ensemblmetazoa:M04F3.5b.1(transcript)|ensemblmetazoa:WBGene00019771(gene)|go:"GO:0003779"(actin binding)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030175"(filopodium)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)|go:"GO:0061024"(membrane organization)|uniprotkb:Q95Y95(identity)|wormbase:WBGene00019771(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 124|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:bMOvoO4LBVIjnKdrG/YFcgmXUCE6239 intact-crc:00DC70CE1D34B6EA|rigid:RqleB4ocXVbZGaDrvqpdVAmrGbI false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10929 uniprotkb:G5EGI2 intact:EBI-315750|ensemblmetazoa:B0336.6.1|ensemblmetazoa:B0336.6.2 intact:EBI-6541649|ensemblmetazoa:Y38C1BA.2a.1 psi-mi:q10929_caeel(display_long)|uniprotkb:abi-1(gene name)|psi-mi:abi-1(display_short)|uniprotkb:CELE_B0336.6(orf name)|uniprotkb:B0336.6(orf name) psi-mi:g5egi2_caeel(display_long)|uniprotkb:Y38C1BA.2(orf name)|uniprotkb:snn-1(gene name)|psi-mi:snn-1(display_short)|uniprotkb:syn(gene name synonym)|uniprotkb:CELE_Y38C1BA.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541645|imex:IM-18681-724 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498224.1|wormbase:B0336.6|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:B0336.6.1(transcript)|ensemblmetazoa:B0336.6.2(transcript)|ensemblmetazoa:WBGene00015146(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028457|interpro:IPR036028|interpro:IPR036993|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|dip:DIP-25719N|reactome:R-CEL-2029482|reactome:R-CEL-5663213|uniprotkb:Q10929(identity)|wormbase:WBGene00015146(identity) ensemblmetazoa:WBGene00004913(gene)|ensemblmetazoa:Y38C1BA.2a.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0046872"(metal ion binding)|refseq:NP_741327.1|wormbase:Y38C1BA.2a|interpro:IPR001359(Synapsin)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020897|interpro:IPR020898|uniprotkb:G5EGI2(identity)|wormbase:WBGene00004913(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:h2OKl99WmqsFH0P8m1amyB6Ft5k6239 rogid:MH29+7Es7PNDOIE7j5XuTk9zSVY6239 intact-crc:8FEBF75826F4B29C|rigid:AMCYIztLeAstdqpVpAmhLwd+00c false sufficient binding region:415-469 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17549 uniprotkb:Q22387 intact:EBI-317283|ensemblmetazoa:C01B7.4b.1|ensemblmetazoa:C01B7.4b.2 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 psi-mi:q17549_caeel(display_long)|uniprotkb:magu-2(gene name)|psi-mi:magu-2(display_short)|uniprotkb:C01B7.4(orf name)|uniprotkb:CELE_C01B7.4(orf name) psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541662|imex:IM-18681-725 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505265.1|ensemblmetazoa:C01B7.4b.1(transcript)|ensemblmetazoa:C01B7.4b.2(transcript)|ensemblmetazoa:WBGene00006467(gene)|go:"GO:0016020"(membrane)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR031185|interpro:IPR035601|interpro:IPR036028|interpro:IPR036034|dip:DIP-25935N|wormbase:C01B7.4b|uniprotkb:Q17549(identity)|wormbase:WBGene00006467(identity) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 23|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:nwVlsT53qNK2xX1+Y0MRfTDT0Tk6239 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 intact-crc:4925E5A95127A105|rigid:Mku/T8qB6ZRoG1vEWnIX74qCh0g false sufficient binding region:340-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBZ8 uniprotkb:Q10457 intact:EBI-6532845|ensemblmetazoa:C01C7.1a.1|uniprotkb:C6KRP0 intact:EBI-311886|ensemblmetazoa:B0286.3.1 psi-mi:ark1_caeel(display_long)|uniprotkb:ark-1(gene name)|psi-mi:ark-1(display_short)|uniprotkb:Ras-regulating kinase ark-1(gene name synonym)|uniprotkb:C01C7.1(orf name) psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541677|imex:IM-18681-726 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C01C7.1a.1(transcript)|ensemblmetazoa:WBGene00000186(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_001255653.1|refseq:NP_001255654.1|wormbase:C01C7.1a|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|wormbase:C01C7.1b|interpro:IPR036028|uniprotkb:C6KRP0(identity)|wormbase:WBGene00000186(identity) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/09/24 rogid:3y4DKCGtK0UAmuo7wGZIoULkmis6239 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 intact-crc:AFBFAA964533BA32|rigid:LzATCTTg+95LxgY+YUtKSi79XOo false sufficient binding region:382-443 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NA61 uniprotkb:G5EBZ8 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 intact:EBI-6532845|ensemblmetazoa:C01C7.1a.1|uniprotkb:C6KRP0 psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:ark1_caeel(display_long)|uniprotkb:ark-1(gene name)|psi-mi:ark-1(display_short)|uniprotkb:Ras-regulating kinase ark-1(gene name synonym)|uniprotkb:C01C7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541692|imex:IM-18681-727 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) ensemblmetazoa:C01C7.1a.1(transcript)|ensemblmetazoa:WBGene00000186(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_001255653.1|refseq:NP_001255654.1|wormbase:C01C7.1a|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|wormbase:C01C7.1b|interpro:IPR036028|uniprotkb:C6KRP0(identity)|wormbase:WBGene00000186(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/09/24 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 rogid:3y4DKCGtK0UAmuo7wGZIoULkmis6239 intact-crc:CE13160ED330461D|rigid:aPK97QY7AUpHS37DoyxNAAGFl+U false - sufficient binding region:382-443 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01761 uniprotkb:O01960 intact:EBI-314725|uniprotkb:Q17362|uniprotkb:Q5W614|uniprotkb:Q5W615|uniprotkb:Q5W616|uniprotkb:Q5W617|uniprotkb:Q646H5|uniprotkb:Q64EQ8|uniprotkb:Q7Z119|uniprotkb:Q7Z120|ensemblmetazoa:C09D1.1b.1|ensemblmetazoa:C09D1.1g.1 intact:EBI-6532858|ensemblmetazoa:C27A12.3.1 psi-mi:unc89_caeel(display_long)|uniprotkb:C09D1.1(orf name)|uniprotkb:Uncoordinated protein 89(gene name synonym)|uniprotkb:unc-89(gene name)|psi-mi:unc-89(display_short)|uniprotkb:Obscurin(gene name synonym)|uniprotkb:Inactive serine/threonine-protein kinase unc-89(gene name synonym) psi-mi:o01960_caeel(display_long)|uniprotkb:let-391(gene name)|psi-mi:let-391(display_short)|uniprotkb:tag-146(gene name synonym)|uniprotkb:C27A12.3(orf name)|uniprotkb:CELE_C27A12.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541722|imex:IM-18681-729 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|refseq:NP_001020984.1|refseq:NP_001020985.1|refseq:NP_001020988.1|refseq:NP_001020989.1|refseq:NP_001020990.1|wormbase:C09D1.1a|wormbase:C09D1.1b|wormbase:C09D1.1c|wormbase:C09D1.1d|wormbase:C09D1.1e|wormbase:C09D1.1f|wormbase:C09D1.1g|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007850(RCSD)|interpro:IPR001452(Src homology-3)|rcsb pdb:1FHO|refseq:NP_001293453.1|refseq:NP_001293454.1|ensemblmetazoa:C09D1.1b.1(transcript)|ensemblmetazoa:C09D1.1g.1(transcript)|ensemblmetazoa:WBGene00006820(gene)|ensemblmetazoa:WBGene00006820(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0014722"(regulation of skeletal muscle contraction by calcium ion signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0090736"(MATH domain binding)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905905"(pharyngeal gland morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR013106(Immunoglobulin V-set)|ensemblmetazoa:WBGene00006820(gene)|uniprotkb:O01761(identity)|wormbase:WBGene00006820(identity) ensemblmetazoa:C27A12.3.1(transcript)|ensemblmetazoa:WBGene00006492(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_491744.3|wormbase:C27A12.3|interpro:IPR036236|uniprotkb:O01960(identity)|wormbase:WBGene00006492(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 54|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:84zR3QKMivdFjveSZ43aBEGX/CM6239 rogid:4XW4eoq2smGQYzFRNpCQivWZwkU6239 intact-crc:DAC564D3F0217658|rigid:RuSPyTyB8yBH7A5zSTFCaPWL8Dg false sufficient binding region:66-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34418 uniprotkb:G5EEN3 intact:EBI-2414758|ensemblmetazoa:F42H10.5a.1|ensemblmetazoa:F42H10.5a.2 intact:EBI-6390483|ensemblmetazoa:C02F4.1.1|ensemblmetazoa:C02F4.1.2 psi-mi:mig39_caeel(display_long)|uniprotkb:mig-39(gene name)|psi-mi:mig-39(display_short)|uniprotkb:Abnormal cell migration protein 39(gene name synonym)|uniprotkb:F42H10.5(orf name) psi-mi:g5een3_caeel(display_long)|uniprotkb:C02F4.1(orf name)|uniprotkb:ced-5(gene name)|psi-mi:ced-5(display_short)|uniprotkb:CELE_C02F4.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541707|imex:IM-18681-728 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|refseq:NP_498871.3|wormbase:F42H10.5a|ensemblmetazoa:F42H10.5a.1(transcript)|ensemblmetazoa:F42H10.5a.2(transcript)|ensemblmetazoa:WBGene00018369(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|uniprotkb:P34418(identity)|wormbase:WBGene00018369(identity) refseq:NP_501938.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR001452(Src homology-3)|wormbase:C02F4.1|ensemblmetazoa:C02F4.1.1(transcript)|ensemblmetazoa:C02F4.1.2(transcript)|ensemblmetazoa:WBGene00000419(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070986"(left/right axis specification)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098793"(presynapse)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|reactome:R-CEL-8980692|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-8849471|interpro:IPR032376|interpro:IPR027357|interpro:IPR035892|interpro:IPR026791|interpro:IPR027007|reactome:R-CEL-6798695|reactome:R-CEL-418885|reactome:R-CEL-983231|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|uniprotkb:G5EEN3(identity)|wormbase:WBGene00000419(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:158MeK38D2MeOP1XnmnZSSukaiM6239 rogid:VnDRU/8V7erZT8Bd92lWDszhwGY6239 intact-crc:603D8F3FECB86E00|rigid:hme0v4ytXBDJj7bCcCnDm5BqdXY false - sufficient binding region:7-69 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44820 uniprotkb:O01761 intact:EBI-318098|ensemblmetazoa:F52C6.3.1 intact:EBI-314725|uniprotkb:Q17362|uniprotkb:Q5W614|uniprotkb:Q5W615|uniprotkb:Q5W616|uniprotkb:Q5W617|uniprotkb:Q646H5|uniprotkb:Q64EQ8|uniprotkb:Q7Z119|uniprotkb:Q7Z120|ensemblmetazoa:C09D1.1b.1|ensemblmetazoa:C09D1.1g.1 psi-mi:o44820_caeel(display_long)|uniprotkb:F52C6.3(orf name)|uniprotkb:CELE_F52C6.3(orf name) psi-mi:unc89_caeel(display_long)|uniprotkb:C09D1.1(orf name)|uniprotkb:Uncoordinated protein 89(gene name synonym)|uniprotkb:unc-89(gene name)|psi-mi:unc-89(display_short)|uniprotkb:Obscurin(gene name synonym)|uniprotkb:Inactive serine/threonine-protein kinase unc-89(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541737|imex:IM-18681-730 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494127.2|wormbase:F52C6.3|ensemblmetazoa:F52C6.3.1(transcript)|ensemblmetazoa:WBGene00018660(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|go:"GO:0016567"(protein ubiquitination)|dip:DIP-24316N|uniprotkb:O44820(identity)|wormbase:WBGene00018660(identity) interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|refseq:NP_001020984.1|refseq:NP_001020985.1|refseq:NP_001020988.1|refseq:NP_001020989.1|refseq:NP_001020990.1|wormbase:C09D1.1a|wormbase:C09D1.1b|wormbase:C09D1.1c|wormbase:C09D1.1d|wormbase:C09D1.1e|wormbase:C09D1.1f|wormbase:C09D1.1g|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007850(RCSD)|interpro:IPR001452(Src homology-3)|rcsb pdb:1FHO|refseq:NP_001293453.1|refseq:NP_001293454.1|ensemblmetazoa:C09D1.1b.1(transcript)|ensemblmetazoa:C09D1.1g.1(transcript)|ensemblmetazoa:WBGene00006820(gene)|ensemblmetazoa:WBGene00006820(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0014722"(regulation of skeletal muscle contraction by calcium ion signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0090736"(MATH domain binding)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905905"(pharyngeal gland morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR013106(Immunoglobulin V-set)|ensemblmetazoa:WBGene00006820(gene)|uniprotkb:O01761(identity)|wormbase:WBGene00006820(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:QuJ7/jGkBkfQqUUmrAJ8OuPtJUo6239 rogid:84zR3QKMivdFjveSZ43aBEGX/CM6239 intact-crc:60FD79DD8E555988|rigid:c+XykG/oP7QSEbaM9XQGwb5PkQU false - sufficient binding region:66-126 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01761 uniprotkb:Q22387 intact:EBI-314725|uniprotkb:Q17362|uniprotkb:Q5W614|uniprotkb:Q5W615|uniprotkb:Q5W616|uniprotkb:Q5W617|uniprotkb:Q646H5|uniprotkb:Q64EQ8|uniprotkb:Q7Z119|uniprotkb:Q7Z120|ensemblmetazoa:C09D1.1b.1|ensemblmetazoa:C09D1.1g.1 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 psi-mi:unc89_caeel(display_long)|uniprotkb:C09D1.1(orf name)|uniprotkb:Uncoordinated protein 89(gene name synonym)|uniprotkb:unc-89(gene name)|psi-mi:unc-89(display_short)|uniprotkb:Obscurin(gene name synonym)|uniprotkb:Inactive serine/threonine-protein kinase unc-89(gene name synonym) psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541752|imex:IM-18681-731 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|refseq:NP_001020984.1|refseq:NP_001020985.1|refseq:NP_001020988.1|refseq:NP_001020989.1|refseq:NP_001020990.1|wormbase:C09D1.1a|wormbase:C09D1.1b|wormbase:C09D1.1c|wormbase:C09D1.1d|wormbase:C09D1.1e|wormbase:C09D1.1f|wormbase:C09D1.1g|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007850(RCSD)|interpro:IPR001452(Src homology-3)|rcsb pdb:1FHO|refseq:NP_001293453.1|refseq:NP_001293454.1|ensemblmetazoa:C09D1.1b.1(transcript)|ensemblmetazoa:C09D1.1g.1(transcript)|ensemblmetazoa:WBGene00006820(gene)|ensemblmetazoa:WBGene00006820(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0014722"(regulation of skeletal muscle contraction by calcium ion signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0090736"(MATH domain binding)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905905"(pharyngeal gland morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR013106(Immunoglobulin V-set)|ensemblmetazoa:WBGene00006820(gene)|uniprotkb:O01761(identity)|wormbase:WBGene00006820(identity) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 32|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:84zR3QKMivdFjveSZ43aBEGX/CM6239 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 intact-crc:E98E5D44F09FBC7E|rigid:nezTTuxCR2s4T7AEf23Y7s+vOw0 false sufficient binding region:66-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01761 uniprotkb:Q9GYG1 intact:EBI-314725|uniprotkb:Q17362|uniprotkb:Q5W614|uniprotkb:Q5W615|uniprotkb:Q5W616|uniprotkb:Q5W617|uniprotkb:Q646H5|uniprotkb:Q64EQ8|uniprotkb:Q7Z119|uniprotkb:Q7Z120|ensemblmetazoa:C09D1.1b.1|ensemblmetazoa:C09D1.1g.1 intact:EBI-314846|ensemblmetazoa:ZC395.8.1 psi-mi:unc89_caeel(display_long)|uniprotkb:C09D1.1(orf name)|uniprotkb:Uncoordinated protein 89(gene name synonym)|uniprotkb:unc-89(gene name)|psi-mi:unc-89(display_short)|uniprotkb:Obscurin(gene name synonym)|uniprotkb:Inactive serine/threonine-protein kinase unc-89(gene name synonym) psi-mi:q9gyg1_caeel(display_long)|uniprotkb:ztf-8(gene name)|psi-mi:ztf-8(display_short)|uniprotkb:CELE_ZC395.8(orf name)|uniprotkb:ZC395.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541767|imex:IM-18681-732 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|refseq:NP_001020984.1|refseq:NP_001020985.1|refseq:NP_001020988.1|refseq:NP_001020989.1|refseq:NP_001020990.1|wormbase:C09D1.1a|wormbase:C09D1.1b|wormbase:C09D1.1c|wormbase:C09D1.1d|wormbase:C09D1.1e|wormbase:C09D1.1f|wormbase:C09D1.1g|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR007850(RCSD)|interpro:IPR001452(Src homology-3)|rcsb pdb:1FHO|refseq:NP_001293453.1|refseq:NP_001293454.1|ensemblmetazoa:C09D1.1b.1(transcript)|ensemblmetazoa:C09D1.1g.1(transcript)|ensemblmetazoa:WBGene00006820(gene)|ensemblmetazoa:WBGene00006820(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0014722"(regulation of skeletal muscle contraction by calcium ion signaling)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0090736"(MATH domain binding)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905905"(pharyngeal gland morphogenesis)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR013106(Immunoglobulin V-set)|ensemblmetazoa:WBGene00006820(gene)|uniprotkb:O01761(identity)|wormbase:WBGene00006820(identity) refseq:NP_498124.2|wormbase:ZC395.8|ensemblmetazoa:WBGene00022598(gene)|ensemblmetazoa:ZC395.8.1(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|dip:DIP-24679N|uniprotkb:Q9GYG1(identity)|wormbase:WBGene00022598(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:84zR3QKMivdFjveSZ43aBEGX/CM6239 rogid:wsZC5q+nCfg+Qz99e0wmwQZxK4A6239 intact-crc:C1B050D0BCC5B3FA|rigid:l02lMEyT1NTJMt1R8oai2d9oWvU false sufficient binding region:66-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFE7 uniprotkb:Q10457 intact:EBI-6541786|ensemblmetazoa:C10F3.6.1|ensemblmetazoa:C10F3.6.2 intact:EBI-311886|ensemblmetazoa:B0286.3.1 psi-mi:fut8_caeel(display_long)|uniprotkb:Fucosyltransferase 8(gene name synonym)|uniprotkb:"GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase"(gene name synonym)|uniprotkb:GDP-fucose--glycoprotein fucosyltransferase(gene name synonym)|uniprotkb:Glycoprotein 6-alpha-L-fucosyltransferase(gene name synonym)|uniprotkb:C10F3.6(orf name)|uniprotkb:fut-8(gene name)|psi-mi:fut-8(display_short) psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541782|imex:IM-18681-733 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C10F3.6.1(transcript)|ensemblmetazoa:C10F3.6.2(transcript)|ensemblmetazoa:WBGene00001508(gene)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008417"(fucosyltransferase activity)|go:"GO:0008424"(glycoprotein 6-alpha-L-fucosyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033578"(protein glycosylation in Golgi)|go:"GO:0036065"(fucosylation)|go:"GO:0036071"(N-glycan fucosylation)|go:"GO:0046702"(galactoside 6-L-fucosyltransferase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046921"("alpha-(1->6)-fucosyltransferase activity")|interpro:IPR001452(Src homology-3)|interpro:IPR015827("Alpha-(1,6)-fucosyltransferase, eukaryotic type")|refseq:NP_504555.2|wormbase:C10F3.6|interpro:IPR027350|reactome:R-CEL-975578|interpro:IPR035653|interpro:IPR036028|uniprotkb:G5EFE7(identity)|wormbase:WBGene00001508(identity) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:gvC/SeMZoeKJ9/0ALFrmpyD3LY46239 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 intact-crc:A1018E85CD6B893D|rigid:Fed2f26r+PLWyZUt3Jt6wDf1zoA false sufficient binding region:492-549 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFE7 uniprotkb:Q19980 intact:EBI-6541786|ensemblmetazoa:C10F3.6.1|ensemblmetazoa:C10F3.6.2 intact:EBI-311852|intact:EBI-2923863|ensemblmetazoa:F32G8.6.1 psi-mi:fut8_caeel(display_long)|uniprotkb:Fucosyltransferase 8(gene name synonym)|uniprotkb:"GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase"(gene name synonym)|uniprotkb:GDP-fucose--glycoprotein fucosyltransferase(gene name synonym)|uniprotkb:Glycoprotein 6-alpha-L-fucosyltransferase(gene name synonym)|uniprotkb:C10F3.6(orf name)|uniprotkb:fut-8(gene name)|psi-mi:fut-8(display_short) psi-mi:gch1_caeel(display_long)|uniprotkb:F32G8.6(orf name)|uniprotkb:cat-4(gene name)|psi-mi:cat-4(display_short)|uniprotkb:GTP cyclohydrolase I(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541799|imex:IM-18681-734 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C10F3.6.1(transcript)|ensemblmetazoa:C10F3.6.2(transcript)|ensemblmetazoa:WBGene00001508(gene)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008417"(fucosyltransferase activity)|go:"GO:0008424"(glycoprotein 6-alpha-L-fucosyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033578"(protein glycosylation in Golgi)|go:"GO:0036065"(fucosylation)|go:"GO:0036071"(N-glycan fucosylation)|go:"GO:0046702"(galactoside 6-L-fucosyltransferase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046921"("alpha-(1->6)-fucosyltransferase activity")|interpro:IPR001452(Src homology-3)|interpro:IPR015827("Alpha-(1,6)-fucosyltransferase, eukaryotic type")|refseq:NP_504555.2|wormbase:C10F3.6|interpro:IPR027350|reactome:R-CEL-975578|interpro:IPR035653|interpro:IPR036028|uniprotkb:G5EFE7(identity)|wormbase:WBGene00001508(identity) reactome:R-CEL-1474151|ensemblmetazoa:F32G8.6.1(transcript)|ensemblmetazoa:WBGene00000298(gene)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006585"(dopamine biosynthetic process from tyrosine)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|refseq:NP_505710.1|wormbase:F32G8.6|dip:DIP-24416N|uniprotkb:Q19980(identity)|wormbase:WBGene00000298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:gvC/SeMZoeKJ9/0ALFrmpyD3LY46239 rogid:U2OFSeuyYv3PuNaKvKKf0CA9KO06239 intact-crc:E4A184F3DEDE467D|rigid:/T5COonmcPePuPigNpcpBpIlMp8 false sufficient binding region:492-549 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NA61 uniprotkb:G5EFE7 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 intact:EBI-6541786|ensemblmetazoa:C10F3.6.1|ensemblmetazoa:C10F3.6.2 psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:fut8_caeel(display_long)|uniprotkb:Fucosyltransferase 8(gene name synonym)|uniprotkb:"GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase"(gene name synonym)|uniprotkb:GDP-fucose--glycoprotein fucosyltransferase(gene name synonym)|uniprotkb:Glycoprotein 6-alpha-L-fucosyltransferase(gene name synonym)|uniprotkb:C10F3.6(orf name)|uniprotkb:fut-8(gene name)|psi-mi:fut-8(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541814|imex:IM-18681-735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) ensemblmetazoa:C10F3.6.1(transcript)|ensemblmetazoa:C10F3.6.2(transcript)|ensemblmetazoa:WBGene00001508(gene)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008417"(fucosyltransferase activity)|go:"GO:0008424"(glycoprotein 6-alpha-L-fucosyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033578"(protein glycosylation in Golgi)|go:"GO:0036065"(fucosylation)|go:"GO:0036071"(N-glycan fucosylation)|go:"GO:0046702"(galactoside 6-L-fucosyltransferase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046921"("alpha-(1->6)-fucosyltransferase activity")|interpro:IPR001452(Src homology-3)|interpro:IPR015827("Alpha-(1,6)-fucosyltransferase, eukaryotic type")|refseq:NP_504555.2|wormbase:C10F3.6|interpro:IPR027350|reactome:R-CEL-975578|interpro:IPR035653|interpro:IPR036028|uniprotkb:G5EFE7(identity)|wormbase:WBGene00001508(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 rogid:gvC/SeMZoeKJ9/0ALFrmpyD3LY46239 intact-crc:2F8A496A17B363B8|rigid:KBJ+7qd4rp3pidvQX+tFomIDQ88 false - sufficient binding region:492-549 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29355 uniprotkb:Q10457 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 intact:EBI-311886|ensemblmetazoa:B0286.3.1 psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541829|imex:IM-18681-736 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 intact-crc:5480DB9AEEF44CF6|rigid:gSbvntdEJ6X/sVWDvd/s2zJJlxg false sufficient binding region:1-57 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29355 uniprotkb:P39055 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541844|imex:IM-18681-737 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:392A608DE1AF6B41|rigid:y4bcDl6A5dior/DLRmCmqSv2WDE false sufficient binding region:1-57 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03575 uniprotkb:P29355 intact:EBI-6541859|ensemblmetazoa:C40H1.5.1 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 psi-mi:ttr5_caeel(display_long)|uniprotkb:ttr-5(gene name)|psi-mi:ttr-5(display_short)|uniprotkb:C40H1.5(orf name) psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541861|imex:IM-18681-738 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C40H1.5.1(transcript)|ensemblmetazoa:WBGene00008040(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0009986"(cell surface)|interpro:IPR001534(Transthyretin-like)|refseq:NP_499054.1|wormbase:C40H1.5|interpro:IPR038479|uniprotkb:Q03575(identity)|wormbase:WBGene00008040(identity) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:50SXck0E85G3LgveA1LQNUXegX86239 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 intact-crc:298F00F6F3A4B96A|rigid:fMkhXFA49+vsMcxTfXGYdD4uP/4 false - sufficient binding region:1-57 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29355 uniprotkb:P34400 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 intact:EBI-2315872|uniprotkb:P34386|uniprotkb:P34403|uniprotkb:Q7JQ80|uniprotkb:Q8WT53|ensemblmetazoa:F10E9.6c.1|ensemblmetazoa:F10E9.6c.2 psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:mig10_caeel(display_long)|uniprotkb:mig-10(gene name)|psi-mi:mig-10(display_short)|uniprotkb:F10E9.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541876|imex:IM-18681-739 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) refseq:NP_001021248.1|refseq:NP_498821.2|refseq:NP_498822.2|wormbase:F10E9.6a|wormbase:F10E9.6b|wormbase:F10E9.6c|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000159(Ras-association)|interpro:IPR029071|reactome:R-CEL-354192|interpro:IPR039664|interpro:IPR039665|reactome:R-CEL-354194|reactome:R-CEL-5674135|ensemblmetazoa:F10E9.6c.1(transcript)|ensemblmetazoa:F10E9.6c.2(transcript)|ensemblmetazoa:WBGene00003243(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0007165"(signal transduction)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018991"(oviposition)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031941"(filamentous actin)|go:"GO:0032584"(growth cone membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0043204"(perikaryon)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099523"(presynaptic cytosol)|uniprotkb:P34400(identity)|wormbase:WBGene00003243(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 rogid:qni0Ph9hE7m4FAxHa2yRYfjO0qY6239 intact-crc:64DC6799AE8003C2|rigid:xibxeZ51HhTNoBRPU9/vK14qVxA false sufficient binding region:1-57 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9TYS3 uniprotkb:P29355 intact:EBI-313731|ensemblmetazoa:D1037.3.1|ensemblmetazoa:D1037.3.2 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 psi-mi:q9tys3_caeel(display_long)|uniprotkb:ftn-2(gene name)|psi-mi:ftn-2(display_short)|uniprotkb:CELE_D1037.3(orf name)|uniprotkb:D1037.3(orf name) psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541891|imex:IM-18681-740 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-917937|refseq:NP_491198.1|wormbase:D1037.3|ensemblmetazoa:D1037.3.1(transcript)|ensemblmetazoa:D1037.3.2(transcript)|ensemblmetazoa:WBGene00001501(gene)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006826"(iron ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|go:"GO:0050830"(defense response to Gram-positive bacterium)|reactome:R-CEL-6798695|dip:DIP-27017N|uniprotkb:Q9TYS3(identity)|wormbase:WBGene00001501(identity) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 35|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:p69JvmHGm4zBtZlWiY8Jqj8155I6239 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 intact-crc:455B0E5746EF835B|rigid:lyybWTKtMnkHlrglm1J0Z9N30VA false - sufficient binding region:157-212 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P29355 uniprotkb:Q65ZB4 intact:EBI-315286|ensemblmetazoa:C14F5.5.1 intact:EBI-6532971|ensemblmetazoa:F54D5.15b.1|ensemblmetazoa:F54D5.15b.2 psi-mi:sem5_caeel(display_long)|uniprotkb:sem-5(gene name)|psi-mi:sem-5(display_short)|uniprotkb:C14F5.5(orf name) psi-mi:q65zb4_caeel(display_long)|uniprotkb:CELE_F54D5.15(orf name)|uniprotkb:F54D5.15(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541906|imex:IM-18681-741 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509342.1|wormbase:C14F5.5|mint:P29355|ensemblmetazoa:C14F5.5.1(transcript)|ensemblmetazoa:WBGene00004774(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0016477"(cell migration)|go:"GO:0030539"(male genitalia development)|go:"GO:0031344"(regulation of cell projection organization)|go:"GO:0040028"(regulation of vulval development)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|rcsb pdb:1K76|rcsb pdb:1KFZ|rcsb pdb:1SEM|rcsb pdb:2SEM|rcsb pdb:3SEM|reactome:R-CEL-109704|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-1433559|reactome:R-CEL-179812|reactome:R-CEL-180292|reactome:R-CEL-182971|reactome:R-CEL-186763|reactome:R-CEL-1963640|reactome:R-CEL-1963642|reactome:R-CEL-2179392|reactome:R-CEL-354194|reactome:R-CEL-375165|reactome:R-CEL-5654689|reactome:R-CEL-5654695|reactome:R-CEL-5654700|reactome:R-CEL-5654706|reactome:R-CEL-5654710|reactome:R-CEL-5654720|reactome:R-CEL-5673001|reactome:R-CEL-6807004|reactome:R-CEL-6811558|reactome:R-CEL-74751|reactome:R-CEL-8851805|reactome:R-CEL-8851907|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|reactome:R-CEL-9607240|dip:DIP-27394N|uniprotkb:P29355(identity)|wormbase:WBGene00004774(identity) ensemblmetazoa:F54D5.15b.1(transcript)|ensemblmetazoa:F54D5.15b.2(transcript)|ensemblmetazoa:WBGene00010057(gene)|refseq:NP_001022200.1|wormbase:F54D5.15b|uniprotkb:Q65ZB4(identity)|wormbase:WBGene00010057(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:tPkptFSxrWMYVHVunFS4kGtmbYU6239 rogid:HNrF4GLN9SQWi6CrHUP8geHepb06239 intact-crc:A194EEB132A50C94|rigid:OTheGpc+0IZXjkq+FpGo5/QLf6A false sufficient binding region:157-212 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10457 uniprotkb:G5ECY0 intact:EBI-311886|ensemblmetazoa:B0286.3.1 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541921|imex:IM-18681-742 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b|uniprotkb:G5ECY0(identity)|wormbase:WBGene00001006(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 intact-crc:82E503429901DF21|rigid:xEesH6oX20Wo6c376ney8BmQD6I false - sufficient binding region:622-689 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21648 uniprotkb:G5ECY0 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541953|imex:IM-18681-744 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b|uniprotkb:G5ECY0(identity)|wormbase:WBGene00001006(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 intact-crc:5625FD20E6F4E835|rigid:ZN8lxsT5UHPX/S8vtp2CAwCEXcg false - sufficient binding region:622-689 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09269 uniprotkb:G5ECY0 intact:EBI-6541936|ensemblmetazoa:C34C12.4.1|ensemblmetazoa:C34C12.4.2 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 psi-mi:yqf4_caeel(display_long)|uniprotkb:C34C12.4(orf name) psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541938|imex:IM-18681-743 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C34C12.4.1(transcript)|ensemblmetazoa:C34C12.4.2(transcript)|ensemblmetazoa:WBGene00007923(gene)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR020309|refseq:NP_497715.2|wormbase:C34C12.4|uniprotkb:Q09269(identity)|wormbase:WBGene00007923(identity) uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b|uniprotkb:G5ECY0(identity)|wormbase:WBGene00001006(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Vsx8Nori5LR5E0kGLRfYaWOfxQ06239 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 intact-crc:91327BC05B54F180|rigid:D5j7FKXgfBwxDn84VdnzgSqwZSQ false - sufficient binding region:622-689 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22227 uniprotkb:G5ECY0 intact:EBI-316403|ensemblmetazoa:T05C12.6a.1|intact:EBI-2315994|intact:EBI-2924320|uniprotkb:G5EC49|uniprotkb:O76471|uniprotkb:Q95ZQ0 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 psi-mi:mig5_caeel(display_long)|uniprotkb:Abnormal cell migration protein 5(gene name synonym)|uniprotkb:T05C12.6(orf name)|uniprotkb:mig-5(gene name)|psi-mi:mig-5(display_short) psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541968|imex:IM-18681-745 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-5663220|refseq:NP_001022316.1|wormbase:T05C12.6a|ensemblmetazoa:T05C12.6a.1(transcript)|ensemblmetazoa:WBGene00003241(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001709"(cell fate determination)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0016477"(cell migration)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030054"(cell junction)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040039"(inductive cell migration)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060069"(Wnt signaling pathway, regulating spindle positioning)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060573"(cell fate specification involved in pattern specification)|go:"GO:0070986"(left/right axis specification)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|go:"GO:0048730"(epidermis morphogenesis)|refseq:NP_001022317.1|refseq:NP_001022318.1|wormbase:T05C12.6b|wormbase:T05C12.6c|dip:DIP-27038N|reactome:R-CEL-201688|reactome:R-CEL-4086400|reactome:R-CEL-4641258|reactome:R-CEL-5099900|reactome:R-CEL-2028269|reactome:R-CEL-4641262|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:G5EC49(identity)|wormbase:WBGene00003241(identity) uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b|uniprotkb:G5ECY0(identity)|wormbase:WBGene00001006(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:Pp8SAvLL8oifjCuQDA+XKc3EON86239 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 intact-crc:FF2CD0017191E484|rigid:ywZaUa2VopgGqvd0EMNltACb99U false - sufficient binding region:622-689 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GYG1 uniprotkb:G5ECY0 intact:EBI-314846|ensemblmetazoa:ZC395.8.1 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 psi-mi:q9gyg1_caeel(display_long)|uniprotkb:ztf-8(gene name)|psi-mi:ztf-8(display_short)|uniprotkb:CELE_ZC395.8(orf name)|uniprotkb:ZC395.8(orf name) psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6541983|imex:IM-18681-746 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498124.2|wormbase:ZC395.8|ensemblmetazoa:WBGene00022598(gene)|ensemblmetazoa:ZC395.8.1(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|dip:DIP-24679N|uniprotkb:Q9GYG1(identity)|wormbase:WBGene00022598(identity) uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b|uniprotkb:G5ECY0(identity)|wormbase:WBGene00001006(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 41|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:wsZC5q+nCfg+Qz99e0wmwQZxK4A6239 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 intact-crc:E7AD920747D45A43|rigid:VHdexSHQ24Jn9EV3fkst9rorqk0 false - sufficient binding region:622-689 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18204 uniprotkb:Q8I7L5 intact:EBI-6533174|ensemblmetazoa:C26C6.8.1 intact:EBI-6541998|ensemblmetazoa:C31H1.6b.1 psi-mi:q18204_caeel(display_long)|uniprotkb:CELE_C26C6.8(orf name)|uniprotkb:C26C6.8(orf name) psi-mi:q8i7l5_caeel(display_long)|uniprotkb:C31H1.6(orf name)|uniprotkb:lntl-1(gene name)|psi-mi:lntl-1(display_short)|uniprotkb:CELE_C31H1.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542000|imex:IM-18681-747 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C26C6.8.1(transcript)|ensemblmetazoa:WBGene00007742(gene)|interpro:IPR001452(Src homology-3)|wormbase:C26C6.8|interpro:IPR036028|refseq:NP_492105.3|uniprotkb:Q18204(identity)|wormbase:WBGene00007742(identity) ensemblmetazoa:C31H1.6b.1(transcript)|ensemblmetazoa:WBGene00016289(gene)|interpro:IPR004991(Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2)|refseq:NP_872099.1|wormbase:C31H1.6b|uniprotkb:Q8I7L5(identity)|wormbase:WBGene00016289(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/01/08 rogid:IPbqqIA5kvCzWAWePaVprEo4Hpw6239 rogid:rdqeDNdnrFXnoS1p26n+hohUqSg6239 intact-crc:39C5CBC2E88B4C2E|rigid:jg6sn1e13tXJrTQAgLFFm7faLiI false sufficient binding region:34-89 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19980 uniprotkb:Q18204 intact:EBI-311852|intact:EBI-2923863|ensemblmetazoa:F32G8.6.1 intact:EBI-6533174|ensemblmetazoa:C26C6.8.1 psi-mi:gch1_caeel(display_long)|uniprotkb:F32G8.6(orf name)|uniprotkb:cat-4(gene name)|psi-mi:cat-4(display_short)|uniprotkb:GTP cyclohydrolase I(gene name synonym) psi-mi:q18204_caeel(display_long)|uniprotkb:CELE_C26C6.8(orf name)|uniprotkb:C26C6.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542015|imex:IM-18681-748 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-1474151|ensemblmetazoa:F32G8.6.1(transcript)|ensemblmetazoa:WBGene00000298(gene)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006585"(dopamine biosynthetic process from tyrosine)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|refseq:NP_505710.1|wormbase:F32G8.6|dip:DIP-24416N|uniprotkb:Q19980(identity)|wormbase:WBGene00000298(identity) ensemblmetazoa:C26C6.8.1(transcript)|ensemblmetazoa:WBGene00007742(gene)|interpro:IPR001452(Src homology-3)|wormbase:C26C6.8|interpro:IPR036028|refseq:NP_492105.3|uniprotkb:Q18204(identity)|wormbase:WBGene00007742(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/01/08 rogid:U2OFSeuyYv3PuNaKvKKf0CA9KO06239 rogid:IPbqqIA5kvCzWAWePaVprEo4Hpw6239 intact-crc:D4365CDB465C767A|rigid:4mq+UteW5ywHmavmdkKjziyrp40 false - sufficient binding region:34-89 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10457 uniprotkb:Q18204 intact:EBI-311886|ensemblmetazoa:B0286.3.1 intact:EBI-6533174|ensemblmetazoa:C26C6.8.1 psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:q18204_caeel(display_long)|uniprotkb:CELE_C26C6.8(orf name)|uniprotkb:C26C6.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542030|imex:IM-18681-749 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) ensemblmetazoa:C26C6.8.1(transcript)|ensemblmetazoa:WBGene00007742(gene)|interpro:IPR001452(Src homology-3)|wormbase:C26C6.8|interpro:IPR036028|refseq:NP_492105.3|uniprotkb:Q18204(identity)|wormbase:WBGene00007742(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/01/08 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 rogid:IPbqqIA5kvCzWAWePaVprEo4Hpw6239 intact-crc:DF5F96EFAF1EF10B|rigid:qSGSwVke2j1X4HrQBpYX11tmVtY false - sufficient binding region:138-194 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19416 uniprotkb:Q18204 intact:EBI-319517|ensemblmetazoa:F13G3.4.1 intact:EBI-6533174|ensemblmetazoa:C26C6.8.1 psi-mi:q19416_caeel(display_long)|uniprotkb:dylt-1(gene name)|psi-mi:dylt-1(display_short)|uniprotkb:F13G3.4(orf name)|uniprotkb:CELE_F13G3.4(orf name) psi-mi:q18204_caeel(display_long)|uniprotkb:CELE_C26C6.8(orf name)|uniprotkb:C26C6.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542045|imex:IM-18681-750 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492063.1|wormbase:F13G3.4|ensemblmetazoa:F13G3.4.1(transcript)|ensemblmetazoa:WBGene00008764(gene)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|dip:DIP-26956N|reactome:R-CEL-6798695|uniprotkb:Q19416(identity)|wormbase:WBGene00008764(identity) ensemblmetazoa:C26C6.8.1(transcript)|ensemblmetazoa:WBGene00007742(gene)|interpro:IPR001452(Src homology-3)|wormbase:C26C6.8|interpro:IPR036028|refseq:NP_492105.3|uniprotkb:Q18204(identity)|wormbase:WBGene00007742(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/01/08 rogid:UL1DI9ebFykwO7Hk7QgxC886Zz46239 rogid:IPbqqIA5kvCzWAWePaVprEo4Hpw6239 intact-crc:802CFF61D69F37F1|rigid:p0Z6UthkOmV3eF5tsNVy1AveBQ4 false - sufficient binding region:138-194 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NA61 uniprotkb:Q18204 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 intact:EBI-6533174|ensemblmetazoa:C26C6.8.1 psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:q18204_caeel(display_long)|uniprotkb:CELE_C26C6.8(orf name)|uniprotkb:C26C6.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542060|imex:IM-18681-751 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) ensemblmetazoa:C26C6.8.1(transcript)|ensemblmetazoa:WBGene00007742(gene)|interpro:IPR001452(Src homology-3)|wormbase:C26C6.8|interpro:IPR036028|refseq:NP_492105.3|uniprotkb:Q18204(identity)|wormbase:WBGene00007742(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/01/08 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 rogid:IPbqqIA5kvCzWAWePaVprEo4Hpw6239 intact-crc:6B9105B99C5242BA|rigid:JkwcC0H8nl4tisS//R+ESOE6Kn4 false - sufficient binding region:138-194 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16612 uniprotkb:O01498 intact:EBI-326132|ensemblmetazoa:B0281.5a.1 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 psi-mi:o16612_caeel(display_long)|uniprotkb:B0281.5(orf name)|uniprotkb:CELE_B0281.5(orf name) psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542075|imex:IM-18681-752 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494230.1|wormbase:B0281.5a|ensemblmetazoa:B0281.5a.1(transcript)|ensemblmetazoa:WBGene00015112(gene)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|dip:DIP-26305N|uniprotkb:O16612(identity)|wormbase:WBGene00015112(identity) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 26|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GQmNkHBJJBBnmrEjJDSy/F6Xmp06239 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 intact-crc:EA24CC800B4E3663|rigid:qGdmybpp+qjyI+LT/aZYskFTrqo false - sufficient binding region:222-277 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91001 uniprotkb:O01498 intact:EBI-313007|ensemblmetazoa:B0547.1.1 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542090|imex:IM-18681-753 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394|uniprotkb:P91001(identity)|wormbase:WBGene00000817(identity) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 intact-crc:ADA1A8D5B87E5706|rigid:C8i7czIQ63PpTYEbxB8M+C+nAxE false - sufficient binding region:222-277 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21366 uniprotkb:O01498 intact:EBI-6542105|ensemblmetazoa:K08H2.2.1 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 psi-mi:q21366_caeel(display_long)|uniprotkb:CELE_K08H2.2(orf name)|uniprotkb:K08H2.2(orf name) psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542107|imex:IM-18681-754 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K08H2.2.1(transcript)|ensemblmetazoa:WBGene00010689(gene)|refseq:NP_510195.1|wormbase:K08H2.2|uniprotkb:Q21366(identity)|wormbase:WBGene00010689(identity) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ZjsZCIdzOWS0ZHiZtCv/kdF43Z06239 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 intact-crc:D74D9F820EB78D87|rigid:99oBSqlE29OT01cAfZm+R0ftp9k false - sufficient binding region:222-277 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B2D6P5 uniprotkb:O01498 intact:EBI-2919829|ensemblmetazoa:M04G12.1c.1|ensemblmetazoa:M04G12.1c.2 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 psi-mi:b2d6p5_caeel(display_long)|uniprotkb:tag-260(gene name)|psi-mi:tag-260(display_short)|uniprotkb:ifbp-1(gene name synonym)|uniprotkb:CELE_M04G12.1(orf name)|uniprotkb:M04G12.1(orf name) psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542122|imex:IM-18681-755 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M04G12.1c.1(transcript)|ensemblmetazoa:M04G12.1c.2(transcript)|ensemblmetazoa:WBGene00010867(gene)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR022750|refseq:NP_001122980.1|wormbase:M04G12.1c|interpro:IPR044882|uniprotkb:B2D6P5(identity)|wormbase:WBGene00010867(identity) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MBUav8DZj3WeqUqpxjtet5cli/w6239 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 intact-crc:F84490C917C22468|rigid:NAHcpl5uue2sKZyQYca40CWWOLY false - sufficient binding region:222-277 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01498 uniprotkb:Q21648 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542137|imex:IM-18681-756 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 25|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 intact-crc:F51973C3EF49C49F|rigid:OgsL5AZpdqviA00XIB/Ayow6QVc false sufficient binding region:222-277 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01498 uniprotkb:Q22387 intact:EBI-331248|uniprotkb:Q8I7I2|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 psi-mi:stam1_caeel(display_long)|uniprotkb:C34G6.7(orf name)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym) psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542152|imex:IM-18681-757 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491710.2|refseq:NP_871813.1|wormbase:C34G6.7a|wormbase:C34G6.7b|reactome:R-CEL-182971|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|dip:DIP-26020N|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR036028|reactome:R-CEL-6807004|reactome:R-CEL-9013420|uniprotkb:O01498(identity)|wormbase:WBGene00004109(identity) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 15|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 intact-crc:2E259257C57C74C5|rigid:vuuUySNO+RAZGTiOv50XOQtVTLw false sufficient binding region:222-277 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:O76337 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-6532169|ensemblmetazoa:F56D2.7.1|uniprotkb:O01421 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:ced6_caeel(display_long)|uniprotkb:ced-6(gene name)|psi-mi:ced-6(display_short)|uniprotkb:Candidate adapter protein ced-6(gene name synonym)|uniprotkb:F56D2.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542167|imex:IM-18681-758 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) ensemblmetazoa:F56D2.7.1(transcript)|ensemblmetazoa:WBGene00000420(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012501"(programmed cell death)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0070986"(left/right axis specification)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|go:"GO:1904747"(positive regulation of apoptotic process involved in development)|go:"GO:0045335"(phagocytic vesicle)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_498203.2|wormbase:F56D2.7|uniprotkb:O76337(identity)|wormbase:WBGene00000420(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 50|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:VjlyH911QZCg4QZbyWiJu1i01cg6239 intact-crc:93A474BD5FFA773F|rigid:X9x+UeFPT7kFnhebUq+DZxCA+7s false sufficient binding region:857-918 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL3 uniprotkb:Q45FX5 intact:EBI-329618|ensemblmetazoa:W07E6.4.1 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 psi-mi:g5ecl3_caeel(display_long)|uniprotkb:prp-21(gene name)|psi-mi:prp-21(display_short)|uniprotkb:W07E6.4(orf name)|uniprotkb:Ceprp21(gene name synonym)|uniprotkb:CELE_W07E6.4(orf name) psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542199|imex:IM-18681-760 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|refseq:NP_493746.1|uniprotkb:Q10577(uniprot-removed-ac)|reactome:R-CEL-72163|wormbase:W07E6.4|interpro:IPR029071|interpro:IPR035967|ensemblmetazoa:W07E6.4.1(transcript)|ensemblmetazoa:WBGene00004188(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR035563|uniprotkb:G5ECL3(identity)|wormbase:WBGene00004188(identity) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:OgSiSCeLk46Ctjas1LZExgzkL/c6239 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 intact-crc:ED2CBAEA79319CE1|rigid:D2ivZ+9c1MCHCcFQTTHRx8zVVWk false - sufficient binding region:857-918 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q45FX5 uniprotkb:B7WNA3 intact:EBI-316741|uniprotkb:Q18479|ensemblmetazoa:C35B8.2b.1 intact:EBI-6542182|ensemblmetazoa:R03C1.1b.1 psi-mi:vav_caeel(display_long)|uniprotkb:C35B8.2(orf name)|uniprotkb:vav-1(gene name)|psi-mi:vav-1(display_short) psi-mi:b7wna3_caeel(display_long)|uniprotkb:CELE_R03C1.1(orf name)|uniprotkb:R03C1.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542184|imex:IM-18681-759 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041222.1|refseq:NP_001041223.1|wormbase:C35B8.2a|wormbase:C35B8.2b|reactome:R-CEL-5218920|reactome:R-CEL-912631|reactome:R-CEL-114604|reactome:R-CEL-1433557|reactome:R-CEL-193648|reactome:R-CEL-3928665|reactome:R-CEL-4420097|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|ensemblmetazoa:C35B8.2b.1(transcript)|ensemblmetazoa:WBGene00006887(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035031|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|dip:DIP-25959N|reactome:R-CEL-416482|reactome:R-CEL-445144|uniprotkb:Q45FX5(identity)|wormbase:WBGene00006887(identity) ensemblmetazoa:R03C1.1b.1(transcript)|ensemblmetazoa:WBGene00010987(gene)|refseq:NP_001254451.1|wormbase:R03C1.1b|uniprotkb:B7WNA3(identity)|wormbase:WBGene00010987(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:66HC+p/DECb10cAG0UeP9vU2vlI6239 rogid:mBjuaoZBAgZYGbYRdHXvbH5dK8M6239 intact-crc:51899E52C7FC6F46|rigid:TsNHAeOCaN3D2Y6b0xVXGKtO/no false sufficient binding region:857-918 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18662 uniprotkb:Q10457 intact:EBI-6542214|ensemblmetazoa:C46H3.2a.1 intact:EBI-311886|ensemblmetazoa:B0286.3.1 psi-mi:q18662_caeel(display_long)|uniprotkb:CELE_C46H3.2(orf name)|uniprotkb:C46H3.2(orf name) psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542216|imex:IM-18681-761 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002110(Ankyrin)|interpro:IPR020683|refseq:NP_001317737.1|ensemblmetazoa:C46H3.2a.1(transcript)|ensemblmetazoa:WBGene00016725(gene)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|wormbase:C46H3.2a|interpro:IPR035497|interpro:IPR035498|interpro:IPR036028|interpro:IPR036770|interpro:IPR027013|uniprotkb:Q18662(identity)|wormbase:WBGene00016725(identity) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:ZVdh3Aw8/UEPobm3HJhbLJRbiio6239 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 intact-crc:E40631E1D0F6C793|rigid:+nYAd3X7YhndPWihGhQqLTjsqys false sufficient binding region:264-324 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:P39055 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542231|imex:IM-18681-762 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 26|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:915BB19C148BC576|rigid:XZzYueX7jfKhetDylaffWuDKYLA false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17577 uniprotkb:Q19253 intact:EBI-6542250|ensemblmetazoa:C06H5.1.1|ensemblmetazoa:C06H5.1.2 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:o17577_caeel(display_long)|uniprotkb:C06H5.1(orf name)|uniprotkb:fbxa-156(gene name)|psi-mi:fbxa-156(display_short)|uniprotkb:CELE_C06H5.1(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542246|imex:IM-18681-763 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C06H5.1.1(transcript)|ensemblmetazoa:C06H5.1.2(transcript)|ensemblmetazoa:WBGene00007392(gene)|interpro:IPR040161|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR002900(Protein of unknown function DUF38, Caenorhabditis species)|refseq:NP_741646.1|wormbase:C06H5.1|interpro:IPR041426|uniprotkb:O17577(identity)|wormbase:WBGene00007392(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 29|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:V5O4Czbhqgv27un2lCWdtVEDOLk6239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:0336061B6C000E94|rigid:RosBMJOGPWFxnbi8d0Ui39K/sSY false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:Q19253 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542263|imex:IM-18681-764 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 33|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:9F6DA16C3D21BE2D|rigid:u61EiF9EUYnp4Tl1xgvr4UrrkhQ false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:O61701 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-6537266 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:o61701_caeel(display_long)|uniprotkb:cyk-1(gene name)|psi-mi:cyk-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542293|imex:IM-18681-766 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) go:"GO:0003779"(actin binding)|go:"GO:0016043"(cellular component organization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|uniprotkb:O61701(identity)|wormbase:WBGene00000872(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:3tZm/rdSqLAK4eIpP1J9faYAo7w6239 intact-crc:693C655B38B21424|rigid:wL76zHJaFbK+bBN8R7/uqhPX3aU false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:Q95QQ9 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-2317344|ensemblmetazoa:C49H3.6a.1 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:q95qq9_caeel(display_long)|uniprotkb:C49H3.6(orf name)|uniprotkb:CELE_C49H3.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542278|imex:IM-18681-765 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) refseq:NP_501316.2|wormbase:C49H3.6a|interpro:IPR019131|ensemblmetazoa:C49H3.6a.1(transcript)|ensemblmetazoa:WBGene00016792(gene)|go:"GO:0005737"(cytoplasm)|uniprotkb:Q95QQ9(identity)|wormbase:WBGene00016792(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:eHT6KUXkocreuSpbjuHpYT+s+tQ6239 intact-crc:14091CEE2EF6F699|rigid:8sFRgO21XNnY6CzRbflF1tuvX0w false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1XFY2 uniprotkb:Q19253 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542308|imex:IM-18681-767 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 24|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:AB0BFD8FBF0FEE82|rigid:7llnqdLGINPA045mioCYBwqsS3c false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:G5ECJ4 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-317668|ensemblmetazoa:F46A9.6.1|ensemblmetazoa:F46A9.6.2|ensemblmetazoa:F46A9.6.3 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:g5ecj4_caeel(display_long)|uniprotkb:mec-8(gene name)|psi-mi:mec-8(display_short)|uniprotkb:F46A9.6(orf name)|uniprotkb:CELE_F46A9.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542323|imex:IM-18681-768 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) uniprotkb:Q19018(uniprot-removed-ac)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_492508.1|rcsb pdb:5TKZ|wormbase:F46A9.6|ensemblmetazoa:F46A9.6.1(transcript)|ensemblmetazoa:F46A9.6.2(transcript)|ensemblmetazoa:F46A9.6.3(transcript)|ensemblmetazoa:WBGene00003172(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048666"(neuron development)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|rcsb pdb:5BJR|interpro:IPR035979|rcsb pdb:6DG0|uniprotkb:G5ECJ4(identity)|wormbase:WBGene00003172(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:wnGDz4nWxQpoavtLjGTr+G//IAM6239 intact-crc:EF42C45287DBA474|rigid:avtlONikZ3ByMz2qjr01P7dmj7I false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:F5GUF0 uniprotkb:Q19253 intact:EBI-6542338|ensemblmetazoa:R06C1.3b.1 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:f5guf0_caeel(display_long)|uniprotkb:R06C1.3(orf name)|uniprotkb:wve-1(gene name)|psi-mi:wve-1(display_short)|uniprotkb:CELE_R06C1.3(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542340|imex:IM-18681-769 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:R06C1.3b.1(transcript)|ensemblmetazoa:WBGene00006958(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031209"(SCAR complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|refseq:NP_001251762.1|wormbase:R06C1.3b|interpro:IPR028288|uniprotkb:F5GUF0(identity)|wormbase:WBGene00006958(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Jmm0mWkD2Esf0E7aV7/qOpEnV906239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:F87161144182EEF1|rigid:5FHUErsRjxPCAoGBw6sXDXb2Xew false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:Q19253 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542355|imex:IM-18681-770 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 19|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 intact-crc:C638B123AC910238|rigid:gzWfLPZ3aKuZTGnATAXDUC/5WU0 false - sufficient binding region:530-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:Q95QA6 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542370|imex:IM-18681-771 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 24|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 intact-crc:920329D4DBBE5BA1|rigid:1xHw3lfN2mgBYfBIS7Kt9Zc8Xas false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19253 uniprotkb:A8XQ35 intact:EBI-6533634|uniprotkb:Q8MQ82|ensemblmetazoa:F09E10.8a.1 intact:EBI-6542385|ensemblmetazoa:Y53H1A.1b.1 psi-mi:toca1_caeel(display_long)|uniprotkb:F09E10.8(orf name)|uniprotkb:toca-1(gene name)|psi-mi:toca-1(display_short) psi-mi:a8xq35_caeel(display_long)|uniprotkb:Y53H1A.1(orf name)|uniprotkb:rsy-1(gene name)|psi-mi:rsy-1(display_short)|uniprotkb:CELE_Y53H1A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542387|imex:IM-18681-772 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|refseq:NP_741722.1|wormbase:F09E10.8b|reactome:R-CEL-8856828|ensemblmetazoa:F09E10.8a.1(transcript)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048613"(embryonic ectodermal digestive tract morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1904703"(negative regulation of protein localization to adherens junction)|ensemblmetazoa:WBGene00017298(gene)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR031160|reactome:R-CEL-9013406|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_741723.1|wormbase:F09E10.8a|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)|uniprotkb:Q19253(identity)|wormbase:WBGene00017298(identity) ensemblmetazoa:WBGene00013177(gene)|ensemblmetazoa:Y53H1A.1b.1(transcript)|go:"GO:0016607"(nuclear speck)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0005634"(nucleus)|interpro:IPR031937|refseq:NP_001122545.2|wormbase:Y53H1A.1b|uniprotkb:A8XQ35(identity)|wormbase:WBGene00013177(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qpvzBircVk89qBiBI9fksnob9zg6239 rogid:buN2kigAdUvAYZ2AhwHTaAMEjSo6239 intact-crc:2A3EE1E1B0292F5E|rigid:0zBviFraojFPt4bq1qzvzjhjDts false sufficient binding region:530-588 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B7WNA3 uniprotkb:P54936 intact:EBI-6542182|ensemblmetazoa:R03C1.1b.1 intact:EBI-315019|ensemblmetazoa:F17E5.1a.1 psi-mi:b7wna3_caeel(display_long)|uniprotkb:CELE_R03C1.1(orf name)|uniprotkb:R03C1.1(orf name) psi-mi:lin2_caeel(display_long)|uniprotkb:lin-2(gene name)|psi-mi:lin-2(display_short)|uniprotkb:F17E5.1(orf name)|uniprotkb:Abnormal cell lineage protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542402|imex:IM-18681-773 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:R03C1.1b.1(transcript)|ensemblmetazoa:WBGene00010987(gene)|refseq:NP_001254451.1|wormbase:R03C1.1b|uniprotkb:B7WNA3(identity)|wormbase:WBGene00010987(identity) refseq:NP_001024587.1|refseq:NP_001024588.1|wormbase:F17E5.1a|wormbase:F17E5.1b|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|mint:P54936|interpro:IPR027417|go:"GO:0005886"(plasma membrane)|ensemblmetazoa:F17E5.1a.1(transcript)|ensemblmetazoa:WBGene00002991(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0018991"(oviposition)|go:"GO:0030054"(cell junction)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|reactome:R-CEL-212676|reactome:R-CEL-6794361|go:"GO:0009791"(post-embryonic development)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036034|uniprotkb:P54936(identity)|wormbase:WBGene00002991(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:mBjuaoZBAgZYGbYRdHXvbH5dK8M6239 rogid:j61SyO9dClve7AUT9ljEmQrMwvk6239 intact-crc:6E30CDF8C949317D|rigid:2m8W/Pl7uFPa8SDOJX5Wvz/LI+A false - sufficient binding region:636-716 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22387 uniprotkb:P54936 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 intact:EBI-315019|ensemblmetazoa:F17E5.1a.1 psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:lin2_caeel(display_long)|uniprotkb:lin-2(gene name)|psi-mi:lin-2(display_short)|uniprotkb:F17E5.1(orf name)|uniprotkb:Abnormal cell lineage protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542417|imex:IM-18681-774 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) refseq:NP_001024587.1|refseq:NP_001024588.1|wormbase:F17E5.1a|wormbase:F17E5.1b|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR011009(Protein kinase-like)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|mint:P54936|interpro:IPR027417|go:"GO:0005886"(plasma membrane)|ensemblmetazoa:F17E5.1a.1(transcript)|ensemblmetazoa:WBGene00002991(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0018991"(oviposition)|go:"GO:0030054"(cell junction)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|reactome:R-CEL-212676|reactome:R-CEL-6794361|go:"GO:0009791"(post-embryonic development)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036034|uniprotkb:P54936(identity)|wormbase:WBGene00002991(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 rogid:j61SyO9dClve7AUT9ljEmQrMwvk6239 intact-crc:BE334B5F9B9F3B5A|rigid:9/r+5aZ+btu+bQJ+boLbHtTPu8o false - sufficient binding region:636-716 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ71 uniprotkb:Q10457 intact:EBI-6538263|ensemblmetazoa:F19C7.8b.1 intact:EBI-311886|ensemblmetazoa:B0286.3.1 psi-mi:q8mq71_caeel(display_long)|uniprotkb:CELE_F19C7.8(orf name)|uniprotkb:F19C7.8(orf name) psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542432|imex:IM-18681-775 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F19C7.8b.1(transcript)|ensemblmetazoa:WBGene00017597(gene)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR039688|refseq:NP_741381.1|wormbase:F19C7.8b|uniprotkb:Q8MQ71(identity)|wormbase:WBGene00017597(identity) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:mg32XU6l6Kkuon9EELwfqIpPP9o6239 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 intact-crc:38059BD06F5FC7DC|rigid:u7s9fReTt4HlWapFOoKzxYnSHvg false sufficient binding region:178-234 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ71 uniprotkb:Q17849 intact:EBI-6538263|ensemblmetazoa:F19C7.8b.1 intact:EBI-317182|ensemblmetazoa:C09B8.6a.1 psi-mi:q8mq71_caeel(display_long)|uniprotkb:CELE_F19C7.8(orf name)|uniprotkb:F19C7.8(orf name) psi-mi:q17849_caeel(display_long)|uniprotkb:hsp-25(gene name)|psi-mi:hsp-25(display_short)|uniprotkb:C09B8.6(orf name)|uniprotkb:CELE_C09B8.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542447|imex:IM-18681-776 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F19C7.8b.1(transcript)|ensemblmetazoa:WBGene00017597(gene)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR039688|refseq:NP_741381.1|wormbase:F19C7.8b|uniprotkb:Q8MQ71(identity)|wormbase:WBGene00017597(identity) refseq:NP_001024374.1|wormbase:C09B8.6a|ensemblmetazoa:C09B8.6a.1(transcript)|ensemblmetazoa:WBGene00002023(gene)|go:"GO:0031430"(M band)|go:"GO:0055120"(striated muscle dense body)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|reactome:R-CEL-4420097|dip:DIP-24962N|uniprotkb:Q17849(identity)|wormbase:WBGene00002023(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:mg32XU6l6Kkuon9EELwfqIpPP9o6239 rogid:5NHvOXjnTCLU2Vz0eMyFik6kUy06239 intact-crc:7E417B20CAFFB7B9|rigid:wwhMkaQ5jwaaTgIklvyPRes6i2M false sufficient binding region:178-234 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ71 uniprotkb:Q19980 intact:EBI-6538263|ensemblmetazoa:F19C7.8b.1 intact:EBI-311852|intact:EBI-2923863|ensemblmetazoa:F32G8.6.1 psi-mi:q8mq71_caeel(display_long)|uniprotkb:CELE_F19C7.8(orf name)|uniprotkb:F19C7.8(orf name) psi-mi:gch1_caeel(display_long)|uniprotkb:F32G8.6(orf name)|uniprotkb:cat-4(gene name)|psi-mi:cat-4(display_short)|uniprotkb:GTP cyclohydrolase I(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542462|imex:IM-18681-777 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F19C7.8b.1(transcript)|ensemblmetazoa:WBGene00017597(gene)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR039688|refseq:NP_741381.1|wormbase:F19C7.8b|uniprotkb:Q8MQ71(identity)|wormbase:WBGene00017597(identity) reactome:R-CEL-1474151|ensemblmetazoa:F32G8.6.1(transcript)|ensemblmetazoa:WBGene00000298(gene)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006585"(dopamine biosynthetic process from tyrosine)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|refseq:NP_505710.1|wormbase:F32G8.6|dip:DIP-24416N|uniprotkb:Q19980(identity)|wormbase:WBGene00000298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:mg32XU6l6Kkuon9EELwfqIpPP9o6239 rogid:U2OFSeuyYv3PuNaKvKKf0CA9KO06239 intact-crc:F9E1C3A6C6F5F4D2|rigid:lxUutgps7g3ZHpmloyjqpRVyYyg false sufficient binding region:178-234 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ71 uniprotkb:Q20759 intact:EBI-6538263|ensemblmetazoa:F19C7.8b.1 intact:EBI-312110|ensemblmetazoa:F54C9.11.1 psi-mi:q8mq71_caeel(display_long)|uniprotkb:CELE_F19C7.8(orf name)|uniprotkb:F19C7.8(orf name) psi-mi:q20759_caeel(display_long)|uniprotkb:F54C9.11(orf name)|uniprotkb:CELE_F54C9.11(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542477|imex:IM-18681-778 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F19C7.8b.1(transcript)|ensemblmetazoa:WBGene00017597(gene)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR039688|refseq:NP_741381.1|wormbase:F19C7.8b|uniprotkb:Q8MQ71(identity)|wormbase:WBGene00017597(identity) refseq:NP_495817.3|ensemblmetazoa:F54C9.11.1(transcript)|ensemblmetazoa:WBGene00010045(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0006887"(exocytosis)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|interpro:IPR040351|wormbase:F54C9.11|reactome:R-CEL-5620912|reactome:R-CEL-5620916|reactome:R-CEL-5620922|dip:DIP-24444N|reactome:R-CEL-8876198|uniprotkb:Q20759(identity)|wormbase:WBGene00010045(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:mg32XU6l6Kkuon9EELwfqIpPP9o6239 rogid:sPGvGy3w4P+cRRYy3dUghqx/A8w6239 intact-crc:C204F556A658089F|rigid:jA2wWXZgIvLRlFsEqqIuZ4S+71k false sufficient binding region:178-234 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21747 uniprotkb:Q8MQ71 intact:EBI-324374|ensemblmetazoa:R05F9.1b.1|ensemblmetazoa:R05F9.1b.2 intact:EBI-6538263|ensemblmetazoa:F19C7.8b.1 psi-mi:q21747_caeel(display_long)|uniprotkb:btbd-10(gene name)|psi-mi:btbd-10(display_short)|uniprotkb:snpc-1.4(gene name synonym)|uniprotkb:CELE_R05F9.1(orf name)|uniprotkb:R05F9.1(orf name) psi-mi:q8mq71_caeel(display_long)|uniprotkb:CELE_F19C7.8(orf name)|uniprotkb:F19C7.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542492|imex:IM-18681-779 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_740981.1|wormbase:R05F9.1b|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR039885|interpro:IPR039886|ensemblmetazoa:R05F9.1b.1(transcript)|ensemblmetazoa:R05F9.1b.2(transcript)|ensemblmetazoa:WBGene00019888(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0042327"(positive regulation of phosphorylation)|uniprotkb:Q21747(identity)|wormbase:WBGene00019888(identity) ensemblmetazoa:F19C7.8b.1(transcript)|ensemblmetazoa:WBGene00017597(gene)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR039688|refseq:NP_741381.1|wormbase:F19C7.8b|uniprotkb:Q8MQ71(identity)|wormbase:WBGene00017597(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qXxgPBZ73WKhACkMLgbuhQ0ksrM6239 rogid:mg32XU6l6Kkuon9EELwfqIpPP9o6239 intact-crc:4281ADFB169F0439|rigid:CCWS/bkR1ySbww/SeKQdS644Qlg false - sufficient binding region:178-234 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ71 uniprotkb:O61710 intact:EBI-6538263|ensemblmetazoa:F19C7.8b.1 intact:EBI-2420012|ensemblmetazoa:R119.2.1 psi-mi:q8mq71_caeel(display_long)|uniprotkb:CELE_F19C7.8(orf name)|uniprotkb:F19C7.8(orf name) psi-mi:o61710_caeel(display_long)|uniprotkb:R119.2(orf name)|uniprotkb:CELE_R119.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542507|imex:IM-18681-780 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F19C7.8b.1(transcript)|ensemblmetazoa:WBGene00017597(gene)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR039688|refseq:NP_741381.1|wormbase:F19C7.8b|uniprotkb:Q8MQ71(identity)|wormbase:WBGene00017597(identity) wormbase:R119.2|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal)|refseq:NP_490725.3|interpro:IPR029149|interpro:IPR036005|ensemblmetazoa:R119.2.1(transcript)|ensemblmetazoa:WBGene00020088(gene)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0008233"(peptidase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0070006"(metalloaminopeptidase activity)|uniprotkb:O61710(identity)|wormbase:WBGene00020088(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:mg32XU6l6Kkuon9EELwfqIpPP9o6239 rogid:hzAP8kYBZklf1GsNUmZtmxY1yYw6239 intact-crc:0CF2E32B320CC179|rigid:nLKC5SGUC7oZfF/XePHnE5awuSU false sufficient binding region:178-234 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ71 uniprotkb:Q9XWR1 intact:EBI-6538263|ensemblmetazoa:F19C7.8b.1 intact:EBI-2002612|intact:EBI-6534487|uniprotkb:A7DTF1|uniprotkb:D3NQA3|ensemblmetazoa:Y11D7A.12a.1 psi-mi:q8mq71_caeel(display_long)|uniprotkb:CELE_F19C7.8(orf name)|uniprotkb:F19C7.8(orf name) psi-mi:flh1_caeel(display_long)|uniprotkb:flh-1(gene name)|psi-mi:flh-1(display_short)|uniprotkb:Y11D7A.12(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542522|imex:IM-18681-781 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F19C7.8b.1(transcript)|ensemblmetazoa:WBGene00017597(gene)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR039688|refseq:NP_741381.1|wormbase:F19C7.8b|uniprotkb:Q8MQ71(identity)|wormbase:WBGene00017597(identity) refseq:NP_501618.2|wormbase:Y11D7A.12a|wormbase:Y11D7A.12b|wormbase:Y11D7A.12c|dip:DIP-24849N|ensemblmetazoa:WBGene00012435(gene)|ensemblmetazoa:Y11D7A.12a.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR007588(Zinc finger, FLYWCH-type)|uniprotkb:A7DTF1(identity)|wormbase:WBGene00012435(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2021/11/30 rogid:mg32XU6l6Kkuon9EELwfqIpPP9o6239 rogid:BUwEONwxmU5dE1HyJh2inla8obA6239 intact-crc:EB4116C5019DC133|rigid:VkwA3YYQBtWz2hdvkWucUAyrF9s false sufficient binding region:178-234 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ71 uniprotkb:Q9BKZ9 intact:EBI-6538263|ensemblmetazoa:F19C7.8b.1 intact:EBI-327986|intact:EBI-6542537|uniprotkb:H2L0Q7|uniprotkb:H2L0Q8|uniprotkb:Q8WQE2|ensemblmetazoa:Y54F10AM.2a.1 psi-mi:q8mq71_caeel(display_long)|uniprotkb:CELE_F19C7.8(orf name)|uniprotkb:F19C7.8(orf name) psi-mi:feh1_caeel(display_long)|uniprotkb:feh-1(gene name)|psi-mi:feh-1(display_short)|uniprotkb:Y54F10AM.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542539|imex:IM-18681-782 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F19C7.8b.1(transcript)|ensemblmetazoa:WBGene00017597(gene)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR039688|refseq:NP_741381.1|wormbase:F19C7.8b|uniprotkb:Q8MQ71(identity)|wormbase:WBGene00017597(identity) uniprotkb:Q8IA96(q8ia96_caeel)|refseq:NP_001022906.1|refseq:NP_001022907.1|refseq:NP_497578.4|wormbase:Y54F10AM.2a|wormbase:Y54F10AM.2b|wormbase:Y54F10AM.2c|ensemblmetazoa:WBGene00001410(gene)|ensemblmetazoa:Y54F10AM.2a.1(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007631"(feeding behavior)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR039576|dip:DIP-25952N|reactome:R-CEL-5693565|uniprotkb:Q8WQE2(identity)|wormbase:WBGene00001410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:mg32XU6l6Kkuon9EELwfqIpPP9o6239 rogid:2Db9uUfwcM9MUGxTnhJ9ysYYef86239 intact-crc:B609D245D70854DD|rigid:ijxg+ulcSTj0SZXKgxpzbHZ3rCc false sufficient binding region:178-234 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ71 uniprotkb:Q9NA61 intact:EBI-6538263|ensemblmetazoa:F19C7.8b.1 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 psi-mi:q8mq71_caeel(display_long)|uniprotkb:CELE_F19C7.8(orf name)|uniprotkb:F19C7.8(orf name) psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542554|imex:IM-18681-783 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F19C7.8b.1(transcript)|ensemblmetazoa:WBGene00017597(gene)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR039688|refseq:NP_741381.1|wormbase:F19C7.8b|uniprotkb:Q8MQ71(identity)|wormbase:WBGene00017597(identity) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:mg32XU6l6Kkuon9EELwfqIpPP9o6239 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 intact-crc:8512EE3C84D09352|rigid:gb1sSGWnjE6Yxul4/wuugBUxvO4 false sufficient binding region:178-234 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEQ3 uniprotkb:Q8MQ71 intact:EBI-319723|ensemblmetazoa:ZK1053.5.1 intact:EBI-6538263|ensemblmetazoa:F19C7.8b.1 psi-mi:g5eeq3_caeel(display_long)|uniprotkb:scrm-2(gene name)|psi-mi:scrm-2(display_short)|uniprotkb:SCRM-2(gene name synonym)|uniprotkb:CELE_ZK1053.5(orf name)|uniprotkb:ZK1053.5(orf name) psi-mi:q8mq71_caeel(display_long)|uniprotkb:CELE_F19C7.8(orf name)|uniprotkb:F19C7.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542569|imex:IM-18681-784 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O18289(uniprot-removed-ac)|ensemblmetazoa:WBGene00014200(gene)|ensemblmetazoa:ZK1053.5.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017128"(phospholipid scramblase activity)|interpro:IPR005552(Scramblase)|refseq:NP_493321.1|interpro:IPR025659|wormbase:ZK1053.5|uniprotkb:G5EEQ3(identity)|wormbase:WBGene00014200(identity) ensemblmetazoa:F19C7.8b.1(transcript)|ensemblmetazoa:WBGene00017597(gene)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR039688|refseq:NP_741381.1|wormbase:F19C7.8b|uniprotkb:Q8MQ71(identity)|wormbase:WBGene00017597(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ayiWZFoWx+GH3NI47lKkWqbGlYY6239 rogid:mg32XU6l6Kkuon9EELwfqIpPP9o6239 intact-crc:586D30ACE3A2EC81|rigid:NC5oVTfsr2yROeQDZkaLBte+gsM false - sufficient binding region:178-234 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17865 uniprotkb:Q19901 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 intact:EBI-326658|ensemblmetazoa:F29D10.4.1 psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:q19901_caeel(display_long)|uniprotkb:hum-1(gene name)|psi-mi:hum-1(display_short)|uniprotkb:CELE_F29D10.4(orf name)|uniprotkb:F29D10.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542584|imex:IM-18681-785 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) refseq:NP_492393.1|wormbase:F29D10.4|ensemblmetazoa:F29D10.4.1(transcript)|ensemblmetazoa:WBGene00002035(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR025660|interpro:IPR027417|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|dip:DIP-24485N|uniprotkb:Q17382(identity)|wormbase:WBGene00002035(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 27|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 rogid:COaNIVxftB8ggxM7ESkx2eOU3Q06239 intact-crc:2AF08D029FE8C29B|rigid:6buw/Zs52Vhz2GTAYJyxKMHin6I false - sufficient binding region:1047-1100 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19275 uniprotkb:Q19901 intact:EBI-315168|ensemblmetazoa:F09F7.5a.1|ensemblmetazoa:F09F7.5a.2|ensemblmetazoa:F09F7.5a.3 intact:EBI-326658|ensemblmetazoa:F29D10.4.1 psi-mi:q19275_caeel(display_long)|uniprotkb:CELE_F09F7.5(orf name)|uniprotkb:F09F7.5(orf name) psi-mi:q19901_caeel(display_long)|uniprotkb:hum-1(gene name)|psi-mi:hum-1(display_short)|uniprotkb:CELE_F29D10.4(orf name)|uniprotkb:F29D10.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542599|imex:IM-18681-786 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498186.1|wormbase:F09F7.5a|go:"GO:0005886"(plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035023"(regulation of Rho protein signal transduction)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR036936|interpro:IPR039056|ensemblmetazoa:WBGene00017302(gene)|ensemblmetazoa:F09F7.5a.1(transcript)|ensemblmetazoa:F09F7.5a.2(transcript)|ensemblmetazoa:F09F7.5a.3(transcript)|dip:DIP-25885N|uniprotkb:Q19275(identity)|wormbase:WBGene00017302(identity) refseq:NP_492393.1|wormbase:F29D10.4|ensemblmetazoa:F29D10.4.1(transcript)|ensemblmetazoa:WBGene00002035(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR025660|interpro:IPR027417|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|dip:DIP-24485N|uniprotkb:Q17382(identity)|wormbase:WBGene00002035(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 127|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:dRcTzChc6E57GiyrC46iYMLP5Tg6239 rogid:COaNIVxftB8ggxM7ESkx2eOU3Q06239 intact-crc:B3AE791DE4208100|rigid:jKsSCq8PaP2pj9tEoAGgZ1QB/o0 false - sufficient binding region:1047-1100 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19901 uniprotkb:Q7JMS4 intact:EBI-326658|ensemblmetazoa:F29D10.4.1 intact:EBI-2416307|ensemblmetazoa:F40F12.5a.1 psi-mi:q19901_caeel(display_long)|uniprotkb:hum-1(gene name)|psi-mi:hum-1(display_short)|uniprotkb:CELE_F29D10.4(orf name)|uniprotkb:F29D10.4(orf name) psi-mi:q7jms4_caeel(display_long)|uniprotkb:cyld-1(gene name)|psi-mi:cyld-1(display_short)|uniprotkb:CELE_F40F12.5(orf name)|uniprotkb:F40F12.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542614|imex:IM-18681-787 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492393.1|wormbase:F29D10.4|ensemblmetazoa:F29D10.4.1(transcript)|ensemblmetazoa:WBGene00002035(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR025660|interpro:IPR027417|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|dip:DIP-24485N|uniprotkb:Q17382(identity)|wormbase:WBGene00002035(identity) interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|reactome:R-CEL-936440|interpro:IPR028889|wormbase:F40F12.5a|refseq:NP_001255045.1|reactome:R-CEL-5689880|interpro:IPR036859|interpro:IPR038765|ensemblmetazoa:F40F12.5a.1(transcript)|ensemblmetazoa:WBGene00009594(gene)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|uniprotkb:Q7JMS4(identity)|wormbase:WBGene00009594(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:COaNIVxftB8ggxM7ESkx2eOU3Q06239 rogid:lumi2pQHnnpm1Z8sBaqMJKJdq0g6239 intact-crc:C5E4DA8933AD93F3|rigid:3KmcSWD05vGuscFouv2/DT4GfXs false sufficient binding region:1047-1100 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19901 uniprotkb:Q1XFY2 intact:EBI-326658|ensemblmetazoa:F29D10.4.1 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 psi-mi:q19901_caeel(display_long)|uniprotkb:hum-1(gene name)|psi-mi:hum-1(display_short)|uniprotkb:CELE_F29D10.4(orf name)|uniprotkb:F29D10.4(orf name) psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542629|imex:IM-18681-788 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492393.1|wormbase:F29D10.4|ensemblmetazoa:F29D10.4.1(transcript)|ensemblmetazoa:WBGene00002035(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR025660|interpro:IPR027417|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|dip:DIP-24485N|uniprotkb:Q17382(identity)|wormbase:WBGene00002035(identity) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:COaNIVxftB8ggxM7ESkx2eOU3Q06239 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 intact-crc:3668144A2126FE7F|rigid:FlwUVJC7uNumzWek3+vF6vYS4LE false sufficient binding region:1047-1100 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:D3YT69 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-6542644|ensemblmetazoa:B0513.1b.1 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:d3yt69_caeel(display_long)|uniprotkb:B0513.1(orf name)|uniprotkb:lin-66(gene name)|psi-mi:lin-66(display_short)|uniprotkb:CELE_B0513.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542646|imex:IM-18681-789 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) ensemblmetazoa:B0513.1b.1(transcript)|ensemblmetazoa:WBGene00001562(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0040034"(regulation of development, heterochronic)|refseq:NP_001255768.1|wormbase:B0513.1b|uniprotkb:D3YT69(identity)|wormbase:WBGene00001562(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 24|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:dvRJsXOYCS7YYQZzmaSFjeMt95o6239 intact-crc:127994F49EF0B1E9|rigid:/tNjKKFbq2t/UwXlWgqL9giJSfM false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:P39055 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542661|imex:IM-18681-790 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 19|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:E42121CBB7D3F38C|rigid:rhqGs16hIutK3q1D8+jv4DZvslw false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:Q17744 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-2315966|ensemblmetazoa:F43B10.1c.1 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:q17744_caeel(display_long)|uniprotkb:CELE_F43B10.1(orf name)|uniprotkb:F43B10.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542676|imex:IM-18681-791 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) interpro:IPR011992(EF-Hand type)|interpro:IPR018247|wormbase:F43B10.1c|refseq:NP_001257277.1|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR041534|ensemblmetazoa:F43B10.1c.1(transcript)|ensemblmetazoa:WBGene00018373(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|uniprotkb:Q17744(identity)|wormbase:WBGene00015548(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:yBu4mQzQP54tuujYZMZhAIVmquE6239 intact-crc:85DCABF53F41E7AA|rigid:Rwt89oEeoOpxWns1Vd+bnFXOcPo false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17865 uniprotkb:Q19951 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542691|imex:IM-18681-792 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:E0B29F1EC18895D2|rigid:5Z1aLyutmJ3r+EfpwRPvMZ7zd2M false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QQ9 uniprotkb:Q19951 intact:EBI-2317344|ensemblmetazoa:C49H3.6a.1 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:q95qq9_caeel(display_long)|uniprotkb:C49H3.6(orf name)|uniprotkb:CELE_C49H3.6(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542706|imex:IM-18681-793 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501316.2|wormbase:C49H3.6a|interpro:IPR019131|ensemblmetazoa:C49H3.6a.1(transcript)|ensemblmetazoa:WBGene00016792(gene)|go:"GO:0005737"(cytoplasm)|uniprotkb:Q95QQ9(identity)|wormbase:WBGene00016792(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eHT6KUXkocreuSpbjuHpYT+s+tQ6239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:5961DDAA6E2C227A|rigid:QE0fz/OUPamsRNcMqg1CmpitdNw false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:Q9TZ84 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-314262|ensemblmetazoa:F54D10.7.1|ensemblmetazoa:F54D10.7.2 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:q9tz84_caeel(display_long)|uniprotkb:F54D10.7(orf name)|uniprotkb:CELE_F54D10.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542721|imex:IM-18681-794 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) refseq:NP_494661.1|wormbase:F54D10.7|ensemblmetazoa:F54D10.7.1(transcript)|ensemblmetazoa:F54D10.7.2(transcript)|ensemblmetazoa:WBGene00018808(gene)|go:"GO:0042802"(identical protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|dip:DIP-25300N|uniprotkb:Q9TZ84(identity)|wormbase:WBGene00018808(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:r7LbwPVye8n/EZ3cklS/Oilkp/Q6239 intact-crc:E35BDED8EB5703AD|rigid:olZfuCSCRxFwdqbSyO6VZahQB3Q false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34450 uniprotkb:Q19951 intact:EBI-325473|uniprotkb:Q8IG18|ensemblmetazoa:F54F2.5a.1 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:ztf1_caeel(display_long)|uniprotkb:F54F2.5(orf name)|uniprotkb:ztf-1(gene name)|psi-mi:ztf-1(display_short) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542736|imex:IM-18681-795 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498942.1|refseq:NP_871662.1|wormbase:F54F2.5a|wormbase:F54F2.5b|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensemblmetazoa:F54F2.5a.1(transcript)|ensemblmetazoa:WBGene00018833(gene)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|uniprotkb:P34450(identity)|wormbase:WBGene00018833(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:95VveFZ4MPq7t/Q/feabYDmibf06239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:64B55F409B463D97|rigid:xq7yn/i4mzg3ixEnXl4n6HVSE0M false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21648 uniprotkb:Q19951 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542751|imex:IM-18681-796 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:727B9B44D8D7359B|rigid:Qlz9LMFy8l+R6vFZntPpqJLKy4g false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21747 uniprotkb:Q19951 intact:EBI-324374|ensemblmetazoa:R05F9.1b.1|ensemblmetazoa:R05F9.1b.2 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:q21747_caeel(display_long)|uniprotkb:btbd-10(gene name)|psi-mi:btbd-10(display_short)|uniprotkb:snpc-1.4(gene name synonym)|uniprotkb:CELE_R05F9.1(orf name)|uniprotkb:R05F9.1(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542766|imex:IM-18681-797 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_740981.1|wormbase:R05F9.1b|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR039885|interpro:IPR039886|ensemblmetazoa:R05F9.1b.1(transcript)|ensemblmetazoa:R05F9.1b.2(transcript)|ensemblmetazoa:WBGene00019888(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0042327"(positive regulation of phosphorylation)|uniprotkb:Q21747(identity)|wormbase:WBGene00019888(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qXxgPBZ73WKhACkMLgbuhQ0ksrM6239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:398A83956E83D68E|rigid:Yy5bENeQ6gWZQyPbwbw8ULvr8xc false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:F5GUF0 uniprotkb:Q19951 intact:EBI-6542338|ensemblmetazoa:R06C1.3b.1 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:f5guf0_caeel(display_long)|uniprotkb:R06C1.3(orf name)|uniprotkb:wve-1(gene name)|psi-mi:wve-1(display_short)|uniprotkb:CELE_R06C1.3(orf name) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542781|imex:IM-18681-798 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:R06C1.3b.1(transcript)|ensemblmetazoa:WBGene00006958(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031209"(SCAR complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|refseq:NP_001251762.1|wormbase:R06C1.3b|interpro:IPR028288|uniprotkb:F5GUF0(identity)|wormbase:WBGene00006958(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Jmm0mWkD2Esf0E7aV7/qOpEnV906239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:88A8E0E89285FE21|rigid:X8nYaps1QQ5ZyOFJJnC2b8FAQ30 false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22227 uniprotkb:Q19951 intact:EBI-316403|ensemblmetazoa:T05C12.6a.1|intact:EBI-2315994|intact:EBI-2924320|uniprotkb:G5EC49|uniprotkb:O76471|uniprotkb:Q95ZQ0 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 psi-mi:mig5_caeel(display_long)|uniprotkb:Abnormal cell migration protein 5(gene name synonym)|uniprotkb:T05C12.6(orf name)|uniprotkb:mig-5(gene name)|psi-mi:mig-5(display_short) psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542796|imex:IM-18681-799 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-5663220|refseq:NP_001022316.1|wormbase:T05C12.6a|ensemblmetazoa:T05C12.6a.1(transcript)|ensemblmetazoa:WBGene00003241(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001709"(cell fate determination)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0016477"(cell migration)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030054"(cell junction)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040039"(inductive cell migration)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060069"(Wnt signaling pathway, regulating spindle positioning)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060573"(cell fate specification involved in pattern specification)|go:"GO:0070986"(left/right axis specification)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|go:"GO:0048730"(epidermis morphogenesis)|refseq:NP_001022317.1|refseq:NP_001022318.1|wormbase:T05C12.6b|wormbase:T05C12.6c|dip:DIP-27038N|reactome:R-CEL-201688|reactome:R-CEL-4086400|reactome:R-CEL-4641258|reactome:R-CEL-5099900|reactome:R-CEL-2028269|reactome:R-CEL-4641262|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:G5EC49(identity)|wormbase:WBGene00003241(identity) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:Pp8SAvLL8oifjCuQDA+XKc3EON86239 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 intact-crc:48D56CF96F32149E|rigid:l2SJZeoEc+oGdVDZjZGdg75uTqo false - sufficient binding region:238-299 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:Q95QA6 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542811|imex:IM-18681-800 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 intact-crc:ED2B5FDBECE25E6A|rigid:UVJbkjXqAuBN3ZOR6DTLZ7fujm4 false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20005 uniprotkb:Q9NA61 intact:EBI-2915449|ensemblmetazoa:F35A5.8a.1 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 psi-mi:q20005_caeel(display_long)|uniprotkb:F35A5.8(orf name)|uniprotkb:CELE_F35A5.8(orf name) psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542841|imex:IM-18681-802 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F35A5.8a.1(transcript)|ensemblmetazoa:WBGene00001335(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR027267|refseq:NP_741756.1|wormbase:F35A5.8a|interpro:IPR004148(BAR)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:Q20005(identity)|wormbase:WBGene00001335(identity) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:HwODK9IV3CjSSkfAa0vHHfzI1MM6239 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 intact-crc:FECE4278993C44ED|rigid:v40977NXAJ2aeWNXHKIQAwDx7p4 false sufficient binding region:310-366 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19951 uniprotkb:Q9BIF4 intact:EBI-6534130|ensemblmetazoa:F32A5.6.1 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 psi-mi:pex13_caeel(display_long)|uniprotkb:prx-13(gene name)|psi-mi:prx-13(display_short)|uniprotkb:Peroxin-13(gene name synonym)|uniprotkb:F32A5.6(orf name) psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542826|imex:IM-18681-801 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F32A5.6.1(transcript)|ensemblmetazoa:WBGene00004198(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR035463|interpro:IPR001452(Src homology-3)|interpro:IPR007223(Peroxin 13, N-terminal)|refseq:NP_495513.1|wormbase:F32A5.6|interpro:IPR036028|reactome:R-CEL-8866654|reactome:R-CEL-9033241|reactome:R-CEL-9603798|uniprotkb:Q19951(identity)|wormbase:WBGene00004198(identity) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/09 rogid:e2i622ru8j8eMl3nd4qzBRuVLH86239 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 intact-crc:184B9AA683F0E892|rigid:25jofjWtrKuKOQfeT0IEaNfJQVg false sufficient binding region:238-299 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34416 uniprotkb:Q10956 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 intact:EBI-6534508|ensemblmetazoa:B0336.11a.1 psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:q10956_caeel(display_long)|uniprotkb:CELE_B0336.11(orf name)|uniprotkb:hpo-28(gene name)|psi-mi:hpo-28(display_short)|uniprotkb:B0336.11(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542856|imex:IM-18681-803 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) reactome:R-CEL-6798695|ensemblmetazoa:B0336.11a.1(transcript)|ensemblmetazoa:WBGene00015148(gene)|go:"GO:0016021"(integral component of membrane)|interpro:IPR013783(Immunoglobulin-like fold)|reactome:R-CEL-9013405|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|refseq:NP_498232.3|wormbase:B0336.11a|interpro:IPR036273|interpro:IPR036865|uniprotkb:Q10956(identity)|wormbase:WBGene00015148(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 rogid:XmcWjzXtZlng2eZf3MXQuh+dfzI6239 intact-crc:634A1E9B240B3CE5|rigid:KGGSy2iutY5El/ttFmCLPBcaAKI false sufficient binding region:269-326 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17865 uniprotkb:P34416 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542871|imex:IM-18681-804 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 44|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 intact-crc:EBA56A8ED7D82C35|rigid:NROBpqCIxoEMVFXeyxmqOcXeFoc false - sufficient binding region:269-326 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34400 uniprotkb:P34416 intact:EBI-2315872|uniprotkb:P34386|uniprotkb:P34403|uniprotkb:Q7JQ80|uniprotkb:Q8WT53|ensemblmetazoa:F10E9.6c.1|ensemblmetazoa:F10E9.6c.2 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 psi-mi:mig10_caeel(display_long)|uniprotkb:mig-10(gene name)|psi-mi:mig-10(display_short)|uniprotkb:F10E9.6(orf name) psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542886|imex:IM-18681-805 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021248.1|refseq:NP_498821.2|refseq:NP_498822.2|wormbase:F10E9.6a|wormbase:F10E9.6b|wormbase:F10E9.6c|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000159(Ras-association)|interpro:IPR029071|reactome:R-CEL-354192|interpro:IPR039664|interpro:IPR039665|reactome:R-CEL-354194|reactome:R-CEL-5674135|ensemblmetazoa:F10E9.6c.1(transcript)|ensemblmetazoa:F10E9.6c.2(transcript)|ensemblmetazoa:WBGene00003243(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0007165"(signal transduction)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018991"(oviposition)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031941"(filamentous actin)|go:"GO:0032584"(growth cone membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0043204"(perikaryon)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099523"(presynaptic cytosol)|uniprotkb:P34400(identity)|wormbase:WBGene00003243(identity) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qni0Ph9hE7m4FAxHa2yRYfjO0qY6239 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 intact-crc:6206CF60A3949E35|rigid:enVjGSvlF18EEVy2qGLom8OwRQE false - sufficient binding region:269-326 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34416 uniprotkb:Q1XFY2 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542901|imex:IM-18681-806 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 21|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 intact-crc:C8BA0F06B00C38C6|rigid:Uuap6r4HY9Li9sYzd+A9V6qTmQo false sufficient binding region:269-326 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34416 uniprotkb:O17905 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 intact:EBI-6534551|ensemblmetazoa:H05G16.1a.1 psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:o17905_caeel(display_long)|uniprotkb:H05G16.1(orf name)|uniprotkb:frm-3(gene name)|psi-mi:frm-3(display_short)|uniprotkb:CELE_H05G16.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542916|imex:IM-18681-807 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) reactome:R-CEL-399955|wormbase:H05G16.1a|ensemblmetazoa:H05G16.1a.1(transcript)|ensemblmetazoa:WBGene00001490(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9035034|reactome:R-CEL-8980692|interpro:IPR000299(Band 4.1, N-terminal)|refseq:NP_509934.2|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041788|uniprotkb:O17905(identity)|wormbase:WBGene00001490(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 rogid:DqAi5bwjB+PKV7pDJe28/eBDS6Y6239 intact-crc:AA6DE062F8E2887A|rigid:V0jbzoCa4j9dYI13KvPsvYjnLS8 false sufficient binding region:269-326 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34416 uniprotkb:G5ED33 intact:EBI-319908|uniprotkb:P34417|uniprotkb:P34421|uniprotkb:Q6AHR7|ensemblmetazoa:F42H10.3a.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:lasp1_caeel(display_long)|uniprotkb:F42H10.3(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542931|imex:IM-18681-808 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498874.2|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036028|wormbase:F42H10.3a|ensemblmetazoa:F42H10.3a.1(transcript)|ensemblmetazoa:WBGene00018367(gene)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|uniprotkb:P34416(identity)|wormbase:WBGene00018367(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:BhFB2FeXVN+iWgNw2lNAEbWJS4k6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:2D55F40CC027FDFA|rigid:Kp1MLO2TX16IX6XLlm+6XJ0XO6E false sufficient binding region:269-326 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1Q247 uniprotkb:Q09989 intact:EBI-2316099|ensemblmetazoa:B0507.3b.1 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:b1q247_caeel(display_long)|uniprotkb:CELE_B0507.3(orf name)|uniprotkb:B0507.3(orf name) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542946|imex:IM-18681-809 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041077.1|wormbase:B0507.3b|ensemblmetazoa:B0507.3b.1(transcript)|ensemblmetazoa:WBGene00015220(gene)|uniprotkb:B1Q247(identity)|wormbase:WBGene00015220(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:kBIurKmudPti6cwGgEZ2n3mxWxI6239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:B2CD0A20481E7FC5|rigid:6mDLlBHaSXxvD8yjFbEo5lM9LoM false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 uniprotkb:P39055 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542961|imex:IM-18681-810 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:59A2EFF67448FF1D|rigid:SGSvxQ1lB7R+d+fkSIj3u9qCl2I false sufficient binding region:430-486 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 uniprotkb:Q18225 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 intact:EBI-6542980|ensemblmetazoa:C26E6.2.1 psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:flh2_caeel(display_long)|uniprotkb:C26E6.2(orf name)|uniprotkb:flh-2(gene name)|psi-mi:flh-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542976|imex:IM-18681-811 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) ensemblmetazoa:C26E6.2.1(transcript)|ensemblmetazoa:WBGene00016138(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR007588(Zinc finger, FLYWCH-type)|refseq:NP_498049.2|wormbase:C26E6.2|uniprotkb:Q18225(identity)|wormbase:WBGene00016138(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:H53A9H3CbM2l/HLncgbQ6QgA8Fg6239 intact-crc:5CA7A4F78C5DB29B|rigid:NFyhZEzqDVyd1Bw+0ffMrMIMwUY false sufficient binding region:430-486 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QQ9 uniprotkb:Q09989 intact:EBI-2317344|ensemblmetazoa:C49H3.6a.1 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:q95qq9_caeel(display_long)|uniprotkb:C49H3.6(orf name)|uniprotkb:CELE_C49H3.6(orf name) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6542993|imex:IM-18681-812 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501316.2|wormbase:C49H3.6a|interpro:IPR019131|ensemblmetazoa:C49H3.6a.1(transcript)|ensemblmetazoa:WBGene00016792(gene)|go:"GO:0005737"(cytoplasm)|uniprotkb:Q95QQ9(identity)|wormbase:WBGene00016792(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eHT6KUXkocreuSpbjuHpYT+s+tQ6239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:E2A522AB47B2ABC5|rigid:CcMJ5KuBzRhsz+borNN5e5eHYCA false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 uniprotkb:Q19275 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 intact:EBI-315168|ensemblmetazoa:F09F7.5a.1|ensemblmetazoa:F09F7.5a.2|ensemblmetazoa:F09F7.5a.3 psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:q19275_caeel(display_long)|uniprotkb:CELE_F09F7.5(orf name)|uniprotkb:F09F7.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543008|imex:IM-18681-813 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) refseq:NP_498186.1|wormbase:F09F7.5a|go:"GO:0005886"(plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035023"(regulation of Rho protein signal transduction)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR036936|interpro:IPR039056|ensemblmetazoa:WBGene00017302(gene)|ensemblmetazoa:F09F7.5a.1(transcript)|ensemblmetazoa:F09F7.5a.2(transcript)|ensemblmetazoa:F09F7.5a.3(transcript)|dip:DIP-25885N|uniprotkb:Q19275(identity)|wormbase:WBGene00017302(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 124|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:dRcTzChc6E57GiyrC46iYMLP5Tg6239 intact-crc:88C313E3381FC494|rigid:pqCHEq8VWRZL/4zY4GuyomJNNEc false sufficient binding region:430-486 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 uniprotkb:Q19849 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 intact:EBI-6543027|ensemblmetazoa:F28B12.2a.1|uniprotkb:D7SFJ5|uniprotkb:D7SFJ6|uniprotkb:D7SFJ7|uniprotkb:D7SFJ8|uniprotkb:D7SFJ9|uniprotkb:Q86NH3|uniprotkb:Q86NH4|uniprotkb:Q86NH5|uniprotkb:Q86NH6|uniprotkb:Q95QI4|uniprotkb:Q9GT31 psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:egl44_caeel(display_long)|uniprotkb:egl-44(gene name)|psi-mi:egl-44(display_short)|uniprotkb:Egg-laying defective protein 44(gene name synonym)|uniprotkb:F28B12.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543023|imex:IM-18681-814 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) ensemblmetazoa:F28B12.2a.1(transcript)|ensemblmetazoa:WBGene00001208(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0035329"(hippo signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|reactome:R-CEL-8951671|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|refseq:NP_495186.3|refseq:NP_741006.3|refseq:NP_741007.2|refseq:NP_871904.2|refseq:NP_871906.2|wormbase:F28B12.2a|wormbase:F28B12.2b|wormbase:F28B12.2c|wormbase:F28B12.2d|wormbase:F28B12.2f|interpro:IPR038096|interpro:IPR041086|reactome:R-CEL-2032785|uniprotkb:Q19849(identity)|wormbase:WBGene00001208(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:sw54s5JuMghi4qfNilvMoFN3bR46239 intact-crc:3A613561BA4C738F|rigid:OIPbjAWY58jM55lb+3nN+5jgLrQ false sufficient binding region:430-486 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 uniprotkb:O16299 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543040|imex:IM-18681-815 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 39|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 intact-crc:5F2A17C3E65359F5|rigid:H1AfBxM8oqL3Hf6nljNtF6Bi9wM false sufficient binding region:430-486 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21648 uniprotkb:Q09989 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543055|imex:IM-18681-816 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:185132E60BF38CF5|rigid:RfPYOLlZRiWkIpqqvenKxOtAUB4 false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P45972 uniprotkb:Q09989 intact:EBI-319208|ensemblmetazoa:T09A5.12.1|ensemblmetazoa:T09A5.12.2 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:ztf17_caeel(display_long)|uniprotkb:T09A5.12(orf name)|uniprotkb:ztf-17(gene name)|psi-mi:ztf-17(display_short) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543070|imex:IM-18681-817 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495656.2|ensemblmetazoa:T09A5.12.1(transcript)|ensemblmetazoa:T09A5.12.2(transcript)|ensemblmetazoa:WBGene00011639(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|reactome:R-CEL-9018519|wormbase:T09A5.12|mint:P45972|dip:DIP-25547N|uniprotkb:P45972(identity)|wormbase:WBGene00011639(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Jbr7OzyYPx/MQ5pGf0AbCedU0BU6239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:2303D8A37C46A6FF|rigid:ca2yVxNLYEltp0a//+YgM0tPSz0 false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 uniprotkb:F5GUA2 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 intact:EBI-6543089|ensemblmetazoa:T14G10.2c.1|ensemblmetazoa:T14G10.2c.2 psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:f5gua2_caeel(display_long)|uniprotkb:T14G10.2(orf name)|uniprotkb:pxf-1(gene name)|psi-mi:pxf-1(display_short)|uniprotkb:CELE_T14G10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543085|imex:IM-18681-818 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) ensemblmetazoa:T14G10.2c.1(transcript)|ensemblmetazoa:T14G10.2c.2(transcript)|ensemblmetazoa:WBGene00004254(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0008544"(epidermis development)|go:"GO:0018996"(molting cycle, collagen and cuticulin-based cuticle)|go:"GO:0040002"(collagen and cuticulin-based cuticle development)|go:"GO:0060102"(collagen and cuticulin-based cuticle extracellular matrix)|refseq:NP_001255467.1|wormbase:T14G10.2c|uniprotkb:F5GUA2(identity)|wormbase:WBGene00004254(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:rCgxvBX+n1kCJuhBXMNnjnmXf1Y6239 intact-crc:0D4ACD935C6BBEB0|rigid:8ikC4j0q0p6ClHL7uljvEgF+zYE false sufficient binding region:430-486 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NAM2 uniprotkb:Q09989 intact:EBI-320941|ensemblmetazoa:Y105C5B.19.1 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:q9nam2_caeel(display_long)|uniprotkb:Y105C5B.19(orf name)|uniprotkb:CELE_Y105C5B.19(orf name) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543102|imex:IM-18681-819 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502908.1|wormbase:Y105C5B.19|ensemblmetazoa:WBGene00013658(gene)|ensemblmetazoa:Y105C5B.19.1(transcript)|go:"GO:0005856"(cytoskeleton)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|dip:DIP-24553N|uniprotkb:Q9NAM2(identity)|wormbase:WBGene00013658(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 32|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ggHSTNIcJwQuCRi6EH+YhrCBgI06239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:4E697E48278CC9F4|rigid:eVp7bf51+n5FZh4MKVG5SefaMRQ false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 uniprotkb:Q9U1W2 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 intact:EBI-330298|uniprotkb:Q9U1W3|ensemblmetazoa:Y62F5A.1b.1 psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:med8_caeel(display_long)|uniprotkb:mdt-8(gene name)|psi-mi:mdt-8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Y62F5A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543117|imex:IM-18681-820 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) refseq:NP_496463.2|refseq:NP_496464.2|wormbase:Y62F5A.1a|wormbase:Y62F5A.1b|dip:DIP-25584N|ensemblmetazoa:WBGene00007013(gene)|ensemblmetazoa:Y62F5A.1b.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|uniprotkb:Q9U1W2(identity)|wormbase:WBGene00007013(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:WqKDjGKtlLjgdrKxf0Hy+LJ/W5g6239 intact-crc:E75311B6B35B3218|rigid:jWmlsjeFB6Mlrs+mZ1iMQW3CzTU false sufficient binding region:430-486 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09989 uniprotkb:Q4VNJ8 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 intact:EBI-2918529 psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543132|imex:IM-18681-821 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 intact-crc:522FFFC4E332CF21|rigid:bsV/EifESD0ip0oC5M6+pVGV7hs false sufficient binding region:430-486 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GYG1 uniprotkb:Q09989 intact:EBI-314846|ensemblmetazoa:ZC395.8.1 intact:EBI-317354|ensemblmetazoa:F45E1.7a.1|ensemblmetazoa:F45E1.7a.2 psi-mi:q9gyg1_caeel(display_long)|uniprotkb:ztf-8(gene name)|psi-mi:ztf-8(display_short)|uniprotkb:CELE_ZC395.8(orf name)|uniprotkb:ZC395.8(orf name) psi-mi:q09989_caeel(display_long)|uniprotkb:sdpn-1(gene name)|psi-mi:sdpn-1(display_short)|uniprotkb:F45E1.7(orf name)|uniprotkb:CELE_F45E1.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543147|imex:IM-18681-822 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498124.2|wormbase:ZC395.8|ensemblmetazoa:WBGene00022598(gene)|ensemblmetazoa:ZC395.8.1(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|dip:DIP-24679N|uniprotkb:Q9GYG1(identity)|wormbase:WBGene00022598(identity) refseq:NP_001024664.1|wormbase:F45E1.7a|ensemblmetazoa:F45E1.7a.1(transcript)|ensemblmetazoa:F45E1.7a.2(transcript)|ensemblmetazoa:WBGene00018467(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0055037"(recycling endosome)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR031160|interpro:IPR036028|dip:DIP-25416N|uniprotkb:Q09989(identity)|wormbase:WBGene00018467(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:wsZC5q+nCfg+Qz99e0wmwQZxK4A6239 rogid:LtJgzh552agq+J1M4fcpSAzNzCI6239 intact-crc:D465A1E46E0B545C|rigid:UaxF7wz826nv5gbyCA+CWQwHs04 false - sufficient binding region:430-486 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:P39055 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543162|imex:IM-18681-823 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 26|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:9BEBC748B2462ED8|rigid:N98o9RGxYw7RG11wpJnmOwOBARk false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q11181 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-2316016|uniprotkb:Q8T3F3|uniprotkb:Q8T3F4|uniprotkb:Q8T3F5|ensemblmetazoa:C05D10.4b.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:ypc4_caeel(display_long)|uniprotkb:C05D10.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543177|imex:IM-18681-824 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) refseq:NP_498323.2|refseq:NP_498324.2|refseq:NP_741170.1|wormbase:C05D10.4a|wormbase:C05D10.4b|wormbase:C05D10.4c|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|ensemblmetazoa:C05D10.4b.1(transcript)|ensemblmetazoa:WBGene00015480(gene)|uniprotkb:Q11181(identity)|wormbase:WBGene00015480(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:msS16ZOpmue9+9+to7VFLPE1TM86239 intact-crc:F896274896EF26D8|rigid:8T60uNnCIzes9I1oFDlrervpQmc false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17744 uniprotkb:O45539 intact:EBI-2315966|ensemblmetazoa:F43B10.1c.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:q17744_caeel(display_long)|uniprotkb:CELE_F43B10.1(orf name)|uniprotkb:F43B10.1(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543192|imex:IM-18681-825 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011992(EF-Hand type)|interpro:IPR018247|wormbase:F43B10.1c|refseq:NP_001257277.1|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR041534|ensemblmetazoa:F43B10.1c.1(transcript)|ensemblmetazoa:WBGene00018373(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|uniprotkb:Q17744(identity)|wormbase:WBGene00015548(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:yBu4mQzQP54tuujYZMZhAIVmquE6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:6D59D01ED51AA4E9|rigid:N7+7WNkN72HMOYet/Bg9IbvP9As false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q09442 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543207|imex:IM-18681-826 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 intact-crc:50907650D94A23A5|rigid:ngmNj5aPzhcXg33DYJF+LKvBKes false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17865 uniprotkb:O45539 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543222|imex:IM-18681-827 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 32|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:4DB551DE9C8360CB|rigid:WMudleyZ1ku0n6Z7+iQUaoxP/zA false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q93203 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-315294|ensemblmetazoa:C11E4.6.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:q93203_caeel(display_long)|uniprotkb:C11E4.6(orf name)|uniprotkb:CELE_C11E4.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543237|imex:IM-18681-828 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) refseq:NP_509620.2|wormbase:C11E4.6|ensemblmetazoa:C11E4.6.1(transcript)|ensemblmetazoa:WBGene00007520(gene)|go:"GO:0005737"(cytoplasm)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|dip:DIP-25879N|uniprotkb:Q93203(identity)|wormbase:WBGene00007520(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 23|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:4lnus3cgxAI4dQDe0XjYAgmH2us6239 intact-crc:02794020E36F1053|rigid:buCQduaeUnnCJDBnWNG7Tr2VuBk false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q18225 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-6542980|ensemblmetazoa:C26E6.2.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:flh2_caeel(display_long)|uniprotkb:C26E6.2(orf name)|uniprotkb:flh-2(gene name)|psi-mi:flh-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543252|imex:IM-18681-829 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) ensemblmetazoa:C26E6.2.1(transcript)|ensemblmetazoa:WBGene00016138(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR007588(Zinc finger, FLYWCH-type)|refseq:NP_498049.2|wormbase:C26E6.2|uniprotkb:Q18225(identity)|wormbase:WBGene00016138(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:H53A9H3CbM2l/HLncgbQ6QgA8Fg6239 intact-crc:D9837C8619EFC722|rigid:sE8tboRt76lfVVe6wvYrcaZZMOc false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QQ9 uniprotkb:O45539 intact:EBI-2317344|ensemblmetazoa:C49H3.6a.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:q95qq9_caeel(display_long)|uniprotkb:C49H3.6(orf name)|uniprotkb:CELE_C49H3.6(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543267|imex:IM-18681-830 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501316.2|wormbase:C49H3.6a|interpro:IPR019131|ensemblmetazoa:C49H3.6a.1(transcript)|ensemblmetazoa:WBGene00016792(gene)|go:"GO:0005737"(cytoplasm)|uniprotkb:Q95QQ9(identity)|wormbase:WBGene00016792(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 19|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eHT6KUXkocreuSpbjuHpYT+s+tQ6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:38365618D6B7D4F4|rigid:FV4+n5F723LCfEaeEl5dJ24Rj00 false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:C1P629 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-6543282|ensemblmetazoa:D1046.1b.1|ensemblmetazoa:D1046.1b.2|ensemblmetazoa:D1046.1b.3 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:c1p629_caeel(display_long)|uniprotkb:D1046.1(orf name)|uniprotkb:cfim-2(gene name)|psi-mi:cfim-2(display_short)|uniprotkb:CELE_D1046.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543284|imex:IM-18681-831 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) ensemblmetazoa:D1046.1b.1(transcript)|ensemblmetazoa:D1046.1b.2(transcript)|ensemblmetazoa:D1046.1b.3(transcript)|ensemblmetazoa:WBGene00008362(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|refseq:NP_001255353.1|wormbase:D1046.1b|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|interpro:IPR034771|interpro:IPR034772|interpro:IPR035979|reactome:R-CEL-73856|uniprotkb:C1P629(identity)|wormbase:WBGene00008362(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:+JtJiDoORwTvoibcdzaybyeZJmw6239 intact-crc:2C142106B898D8A3|rigid:Is9NPStdjcV9NlLWhNkHkWJNl/Y false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q09294 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-331752|ensemblmetazoa:EEED8.3.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:yqo3_caeel(display_long)|uniprotkb:EEED8.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543299|imex:IM-18681-832 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) refseq:NP_495025.1|wormbase:EEED8.3|dip:DIP-27203N|ensemblmetazoa:EEED8.3.1(transcript)|ensemblmetazoa:WBGene00017134(gene)|interpro:IPR012674(Calycin)|uniprotkb:Q09294(identity)|wormbase:WBGene00017134(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 13|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:B4doYlogttP4QdgNfqPKjjN7zmw6239 intact-crc:371B00FB11C9F448|rigid:oGrUzufhYhm5gU7wwqktO1/n6X4 false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O61701 uniprotkb:O45539 intact:EBI-6537266 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:o61701_caeel(display_long)|uniprotkb:cyk-1(gene name)|psi-mi:cyk-1(display_short) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543314|imex:IM-18681-833 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003779"(actin binding)|go:"GO:0016043"(cellular component organization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|uniprotkb:O61701(identity)|wormbase:WBGene00000872(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 18|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:3tZm/rdSqLAK4eIpP1J9faYAo7w6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:D603EF90209426CA|rigid:WcQAl8b2Gho3mrq0uKoEOzXP45k false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q19849 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-6543027|ensemblmetazoa:F28B12.2a.1|uniprotkb:D7SFJ5|uniprotkb:D7SFJ6|uniprotkb:D7SFJ7|uniprotkb:D7SFJ8|uniprotkb:D7SFJ9|uniprotkb:Q86NH3|uniprotkb:Q86NH4|uniprotkb:Q86NH5|uniprotkb:Q86NH6|uniprotkb:Q95QI4|uniprotkb:Q9GT31 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:egl44_caeel(display_long)|uniprotkb:egl-44(gene name)|psi-mi:egl-44(display_short)|uniprotkb:Egg-laying defective protein 44(gene name synonym)|uniprotkb:F28B12.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543329|imex:IM-18681-834 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) ensemblmetazoa:F28B12.2a.1(transcript)|ensemblmetazoa:WBGene00001208(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0035329"(hippo signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|reactome:R-CEL-8951671|interpro:IPR000818(TEA/ATTS)|interpro:IPR016361(Transcriptional enhancer factor)|refseq:NP_495186.3|refseq:NP_741006.3|refseq:NP_741007.2|refseq:NP_871904.2|refseq:NP_871906.2|wormbase:F28B12.2a|wormbase:F28B12.2b|wormbase:F28B12.2c|wormbase:F28B12.2d|wormbase:F28B12.2f|interpro:IPR038096|interpro:IPR041086|reactome:R-CEL-2032785|uniprotkb:Q19849(identity)|wormbase:WBGene00001208(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:sw54s5JuMghi4qfNilvMoFN3bR46239 intact-crc:7D05531EC841488B|rigid:iTbTMAsMoTXA1Iv3/rwN+9atVA8 false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q7JMS4 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-2416307|ensemblmetazoa:F40F12.5a.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:q7jms4_caeel(display_long)|uniprotkb:cyld-1(gene name)|psi-mi:cyld-1(display_short)|uniprotkb:CELE_F40F12.5(orf name)|uniprotkb:F40F12.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543344|imex:IM-18681-835 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|reactome:R-CEL-936440|interpro:IPR028889|wormbase:F40F12.5a|refseq:NP_001255045.1|reactome:R-CEL-5689880|interpro:IPR036859|interpro:IPR038765|ensemblmetazoa:F40F12.5a.1(transcript)|ensemblmetazoa:WBGene00009594(gene)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|uniprotkb:Q7JMS4(identity)|wormbase:WBGene00009594(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:lumi2pQHnnpm1Z8sBaqMJKJdq0g6239 intact-crc:84940559E47AD0F7|rigid:nV07XZJ/1/iuR+h6F4y2/NJ0Wp8 false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q966J6 uniprotkb:O45539 intact:EBI-327612|ensemblmetazoa:F41B4.1.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:q966j6_caeel(display_long)|uniprotkb:F41B4.1(orf name)|uniprotkb:CELE_F41B4.1(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543359|imex:IM-18681-836 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509148.2|wormbase:F41B4.1|ensemblmetazoa:F41B4.1.1(transcript)|ensemblmetazoa:WBGene00018257(gene)|dip:DIP-26336N|uniprotkb:Q966J6(identity)|wormbase:WBGene00018257(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:daBFAeewQ1vhaxj4tlw0watbWpw6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:7B0185B692621DE1|rigid:QMTkck7utICEKMQrzOLb6/YG7Bw false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q1XFY2 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543374|imex:IM-18681-837 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 intact-crc:8F12332A3002987E|rigid:HZQkFHTPhyhHEkpe0VsrMTgqE3E false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03601 uniprotkb:O45539 intact:EBI-314158|uniprotkb:Q23510|ensemblmetazoa:F54G8.4a.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:nhl1_caeel(display_long)|uniprotkb:nhl-1(gene name)|psi-mi:nhl-1(display_short)|uniprotkb:F54G8.4(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543389|imex:IM-18681-838 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499028.1|ensemblmetazoa:F54G8.4a.1(transcript)|ensemblmetazoa:WBGene00003597(gene)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030371"(translation repressor activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|wormbase:F54G8.4a|dip:DIP-26359N|uniprotkb:Q03601(identity)|wormbase:WBGene00003597(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:vg7P1U2gPP4ytoSs2LQ+HsIi60Q6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:5B716B3ABA8DD690|rigid:1YUl3L+mcyNWR1GIFNXrjv5CrT8 false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:O01900 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543404|imex:IM-18681-839 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 intact-crc:C5E7A3B1F801E46B|rigid:zGDrYa6B/Rwcvt21qBV+9uc92eQ false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19019 uniprotkb:O45539 intact:EBI-315356|ensemblmetazoa:M02A10.3a.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:q19019_caeel(display_long)|uniprotkb:sli-1(gene name)|psi-mi:sli-1(display_short)|uniprotkb:CELE_M02A10.3(orf name)|uniprotkb:M02A10.3(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543419|imex:IM-18681-840 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-8849469|refseq:NP_508145.2|wormbase:M02A10.3a|reactome:R-CEL-1433559|reactome:R-CEL-182971|reactome:R-CEL-912631|reactome:R-CEL-983168|ensemblmetazoa:M02A10.3a.1(transcript)|ensemblmetazoa:WBGene00004829(gene)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0045121"(membrane raft)|go:"GO:0047690"(aspartyltransferase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR017907|interpro:IPR018247|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|reactome:R-CEL-6807004|dip:DIP-25788N|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:Q19019(identity)|wormbase:WBGene00004829(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:/BtQ1wHY5H3olzNJgVCi9T+2aj86239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:5028578B8EDB9F7F|rigid:4bsUDP6DJYxrxOe1bgaxsYNQBXc false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21648 uniprotkb:O45539 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543434|imex:IM-18681-841 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:D13B7284A720B127|rigid:fBdryhBy/EWwtrmHjs58l9zPPYU false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:F5GUF0 uniprotkb:O45539 intact:EBI-6542338|ensemblmetazoa:R06C1.3b.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:f5guf0_caeel(display_long)|uniprotkb:R06C1.3(orf name)|uniprotkb:wve-1(gene name)|psi-mi:wve-1(display_short)|uniprotkb:CELE_R06C1.3(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543449|imex:IM-18681-842 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:R06C1.3b.1(transcript)|ensemblmetazoa:WBGene00006958(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031209"(SCAR complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|refseq:NP_001251762.1|wormbase:R06C1.3b|interpro:IPR028288|uniprotkb:F5GUF0(identity)|wormbase:WBGene00006958(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Jmm0mWkD2Esf0E7aV7/qOpEnV906239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:F1A294047C11301A|rigid:Tx7VqBTJVXlJBDoi7RayQNeYQOs false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q22002 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-2316177|ensemblmetazoa:R166.1a.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:mab10_caeel(display_long)|uniprotkb:mab-10(gene name)|psi-mi:mab-10(display_short)|uniprotkb:Protein male abnormal 10(gene name synonym)|uniprotkb:R166.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543464|imex:IM-18681-843 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) interpro:IPR006989(Nab, central region)|interpro:IPR006988(Nab, N-terminal)|interpro:IPR038398|wormbase:R166.1a|refseq:NP_496268.2|interpro:IPR039040|reactome:R-CEL-9031628|ensemblmetazoa:R166.1a.1(transcript)|ensemblmetazoa:WBGene00003107(gene)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010458"(exit from mitosis)|go:"GO:0022404"(molting cycle process)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|uniprotkb:Q22002(identity)|wormbase:WBGene00003107(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:zhw1NK4weat9xTi6VsVXhJSaq+o6239 intact-crc:9866FC117C26F8D3|rigid:WRYFhaoHk+vEMaDtaDLEkDhmHO4 false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q22387 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543479|imex:IM-18681-844 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 15|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 intact-crc:F695E1F38A045115|rigid:PF2RZfiwEyPGrgJEDBuwW4h4Luc false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:G5EC72 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543494|imex:IM-18681-845 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:C9E2CF5182072ECD|rigid:CulXafUDYWoWKbcz2dyKOSCgY2o false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:O45539 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543509|imex:IM-18681-846 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:6AE5134437FA969B|rigid:S/g89BYdDy4iauVC7eTM0yOv3mA false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:G5EGI2 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-6541649|ensemblmetazoa:Y38C1BA.2a.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:g5egi2_caeel(display_long)|uniprotkb:Y38C1BA.2(orf name)|uniprotkb:snn-1(gene name)|psi-mi:snn-1(display_short)|uniprotkb:syn(gene name synonym)|uniprotkb:CELE_Y38C1BA.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543524|imex:IM-18681-847 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) ensemblmetazoa:WBGene00004913(gene)|ensemblmetazoa:Y38C1BA.2a.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0046872"(metal ion binding)|refseq:NP_741327.1|wormbase:Y38C1BA.2a|interpro:IPR001359(Synapsin)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020897|interpro:IPR020898|uniprotkb:G5EGI2(identity)|wormbase:WBGene00004913(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:MH29+7Es7PNDOIE7j5XuTk9zSVY6239 intact-crc:320771A7869FC4BE|rigid:0QSolOsj1GlN4RcpBKiv8GWbHNU false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:Q9U290 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-6535173|ensemblmetazoa:Y48C3A.12.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:q9u290_caeel(display_long)|uniprotkb:CELE_Y48C3A.12(orf name)|uniprotkb:Y48C3A.12(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543539|imex:IM-18681-848 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) reactome:R-CEL-2672351|ensemblmetazoa:WBGene00012994(gene)|ensemblmetazoa:Y48C3A.12.1(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000580(TSC-22 / Dip / Bun)|refseq:NP_496820.3|wormbase:Y48C3A.12|uniprotkb:Q9U290(identity)|wormbase:WBGene00012994(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 25|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:j5mfkqYUtbsxlXm88eVGbYZKfe46239 intact-crc:6B2A45B338410266|rigid:8imefloC/oEMOrURxJEIRLqIcwE false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45539 uniprotkb:G5ED33 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543554|imex:IM-18681-849 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 15|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:8DAB4A343651D7E4|rigid:AsrSvdrn7C9mT2A/rElkmwhmCVM false sufficient binding region:60-117 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q965S4 uniprotkb:O45539 intact:EBI-6543569|ensemblmetazoa:Y75B7AL.4a.1 intact:EBI-315334|ensemblmetazoa:F49B2.5.1 psi-mi:q965s4_caeel(display_long)|uniprotkb:Y75B7AL.4(orf name)|uniprotkb:rga-4(gene name)|psi-mi:rga-4(display_short)|uniprotkb:CELE_Y75B7AL.4(orf name) psi-mi:src2_caeel(display_long)|uniprotkb:SRC oncogene related protein 2(gene name synonym)|uniprotkb:kin-22(gene name synonym)|uniprotkb:F49B2.5(orf name)|uniprotkb:src-2(gene name)|psi-mi:src-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543571|imex:IM-18681-850 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00022286(gene)|ensemblmetazoa:Y75B7AL.4a.1(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|refseq:NP_001041201.1|wormbase:Y75B7AL.4a|interpro:IPR042869|uniprotkb:Q965S4(identity)|wormbase:WBGene00022286(identity) refseq:NP_493502.1|wormbase:F49B2.5|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060465"(pharynx development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|ensemblmetazoa:F49B2.5.1(transcript)|ensemblmetazoa:WBGene00005078(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|reactome:R-CEL-6798695|dip:DIP-26743N|reactome:R-CEL-8948751|uniprotkb:O17539(identity)|wormbase:WBGene00005078(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:cZN9jViHhw0oCtFzP2vrW7Lpmx06239 rogid:VcIBvC1FekvXf5o+UIwLlHHquJo6239 intact-crc:3FD6771DF39E12A1|rigid:qF3lFI8OKmT0NB3/vkwK/S8bSPM false - sufficient binding region:60-117 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17865 uniprotkb:A6ZJ46 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543586|imex:IM-18681-851 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 32|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 intact-crc:AAB5214BE08C045C|rigid:isCQZOIo50yx99c+fY5uEnFMEQs false - sufficient binding region:467-522 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:Q18076 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-2921846|ensemblmetazoa:C18B2.5a.1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:q18076_caeel(display_long)|uniprotkb:C18B2.5(orf name)|uniprotkb:CELE_C18B2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543601|imex:IM-18681-852 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) ensemblmetazoa:C18B2.5a.1(transcript)|ensemblmetazoa:WBGene00015956(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR027417|refseq:NP_741750.1|wormbase:C18B2.5a|dip:DIP-25136N|uniprotkb:Q18076(identity)|wormbase:WBGene00015956(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 37|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:mcd3NaSPJ6tU4fMyCuPRAuL4QOw6239 intact-crc:3E46BCAC4B73EA3F|rigid:POEKQ3lMk8Ce8hJHtat5jBtKL9I false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:O17605 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-6543616|ensemblmetazoa:C26E1.2a.1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:o17605_caeel(display_long)|uniprotkb:CELE_C26E1.2(orf name)|uniprotkb:C26E1.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543618|imex:IM-18681-853 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) ensemblmetazoa:C26E1.2a.1(transcript)|ensemblmetazoa:WBGene00007748(gene)|refseq:NP_001256496.1|wormbase:C26E1.2a|uniprotkb:O17605(identity)|wormbase:WBGene00007748(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 21|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:Gv+1Vy4rp8fm0Gcm34LyPORRwGY6239 intact-crc:1FC126D677EF2C25|rigid:tEvdWYHE4p+86SwxrCHzOLrFikM false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:Q18412 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-2412785|uniprotkb:W6SBE3|ensemblmetazoa:C33H5.15b.1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:sgo1_caeel(display_long)|uniprotkb:C33H5.15(orf name)|uniprotkb:sgo-1(gene name)|psi-mi:sgo-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543633|imex:IM-18681-854 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) interpro:IPR011516(Shugoshin, N-terminal)|refseq:NP_501290.2|wormbase:C33H5.15a|wormbase:C33H5.15b|refseq:NP_001294168.1|ensemblmetazoa:C33H5.15b.1(transcript)|ensemblmetazoa:WBGene00016381(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|uniprotkb:Q18412(identity)|wormbase:WBGene00016381(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/03/02 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:l3NDIRayIpgSPJBRy5J9En7HRk46239 intact-crc:4333FE873074CEC7|rigid:ByOBzcEiTPSOrpGa5EwDchnAdA8 false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:Q20435 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-326825|ensemblmetazoa:F45E6.2.1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:q20435_caeel(display_long)|uniprotkb:atf-6(gene name)|psi-mi:atf-6(display_short)|uniprotkb:CELE_F45E6.2(orf name)|uniprotkb:F45E6.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543648|imex:IM-18681-855 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) refseq:NP_510094.1|wormbase:F45E6.2|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0035966"(response to topologically incorrect protein)|go:"GO:1904576"(response to tunicamycin)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|ensemblmetazoa:F45E6.2.1(transcript)|ensemblmetazoa:WBGene00000222(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|dip:DIP-26021N|reactome:R-CEL-381033|uniprotkb:Q20435(identity)|wormbase:WBGene00000222(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:oUUtoG6kNiIOSgtC6oehKbuj8/g6239 intact-crc:B76C681A16648DB7|rigid:EU67lfhe4EXsXyhAc5tLJxNGctI false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:Q9XVN3 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-6534803|ensemblmetazoa:F46F3.4a.1|uniprotkb:E0AHC9|uniprotkb:E0AHD0|uniprotkb:E0AHD1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:iaspp_caeel(display_long)|uniprotkb:ape-1(gene name)|psi-mi:ape-1(display_short)|uniprotkb:Ce-iASPP(gene name synonym)|uniprotkb:Inhibitor member of the ASPP family(gene name synonym)|uniprotkb:F46F3.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543663|imex:IM-18681-856 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) ensemblmetazoa:F46F3.4a.1(transcript)|ensemblmetazoa:WBGene00000146(gene)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:NP_001256353.1|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|wormbase:F46F3.4a|interpro:IPR036028|interpro:IPR036770|refseq:NP_001256354.1|refseq:NP_001256355.1|refseq:NP_001256356.1|wormbase:F46F3.4b|wormbase:F46F3.4c|wormbase:F46F3.4d|uniprotkb:Q9XVN3(identity)|wormbase:WBGene00000146(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 41|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:Y7YswK3q0/HwOelbHJOIgFi08AA6239 intact-crc:B7E776960F8F15B5|rigid:DSV7UeHQmh2nvIRXqM8c6jIw3CQ false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:O16850 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-324028|uniprotkb:O16849|uniprotkb:O18676|uniprotkb:Q86S42|intact:EBI-1770827|uniprotkb:F3NWW7|uniprotkb:F3NWX0|uniprotkb:G4RQR7|uniprotkb:G4S686|uniprotkb:G4SKG3|uniprotkb:G4SKH0|ensemblmetazoa:R13H8.1h.1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:foxo_caeel(display_long)|uniprotkb:Abnormal dauer formation protein 16(gene name synonym)|uniprotkb:daf-16(gene name)|psi-mi:daf-16(display_short)|uniprotkb:R13H8.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543678|imex:IM-18681-857 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) refseq:NP_001021593.1|refseq:NP_001021594.1|refseq:NP_001021595.1|refseq:NP_001021597.1|wormbase:R13H8.1a|wormbase:R13H8.1b|wormbase:R13H8.1c|wormbase:R13H8.1e|refseq:NP_001021596.1|reactome:R-CEL-9607240|refseq:NP_001021598.2|refseq:NP_001251490.1|refseq:NP_001251492.1|reactome:R-CEL-9614399|reactome:R-CEL-9615017|reactome:R-CEL-9617629|wormbase:R13H8.1d|wormbase:R13H8.1f|wormbase:R13H8.1g|wormbase:R13H8.1h|ensemblmetazoa:R13H8.1h.1(transcript)|ensemblmetazoa:WBGene00000912(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002119"(nematode larval development)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0007614"(short-term memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0009411"(response to UV)|go:"GO:0010286"(heat acclimation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0040024"(dauer larval development)|go:"GO:0042594"(response to starvation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061065"(regulation of dauer larval development)|go:"GO:0061066"(positive regulation of dauer larval development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900075"(positive regulation of neuromuscular synaptic transmission)|go:"GO:1900426"(positive regulation of defense response to bacterium)|go:"GO:1905909"(regulation of dauer entry)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|go:"GO:0045087"(innate immune response)|reactome:R-CEL-198693|reactome:R-CEL-211163|reactome:R-CEL-5687128|dip:DIP-25581N|reactome:R-CEL-5689880|reactome:R-CEL-1181150|reactome:R-CEL-9617828|reactome:R-CEL-9634638|uniprotkb:O16850(identity)|wormbase:WBGene00000912(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 26|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:UfAMA8NPgcJv93n6XAjW5mLboZQ6239 intact-crc:6997FA3F8D8C0937|rigid:c2P4lBQljvbE7FUTGUPxT+ls5d8 false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 uniprotkb:Q22696 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 intact:EBI-328387|ensemblmetazoa:T23F11.4.1 psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:q22696_caeel(display_long)|uniprotkb:T23F11.4(orf name)|uniprotkb:CELE_T23F11.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543693|imex:IM-18681-858 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) refseq:NP_497952.1|wormbase:T23F11.4|dip:DIP-24429N|ensemblmetazoa:T23F11.4.1(transcript)|ensemblmetazoa:WBGene00011956(gene)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|uniprotkb:Q22696(identity)|wormbase:WBGene00011956(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:xAoxh4Urkwg45KvR1aP8C/nM9w86239 intact-crc:45FC46AE27441228|rigid:3wlir4m1d3+VVflRGm++Qy99pgU false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02174 uniprotkb:A6ZJ46 intact:EBI-2315779|ensemblmetazoa:W05H7.4a.1 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 psi-mi:o02174_caeel(display_long)|uniprotkb:zfp-3(gene name)|psi-mi:zfp-3(display_short)|uniprotkb:CELE_W05H7.4(orf name)|uniprotkb:W05H7.4(orf name) psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543708|imex:IM-18681-859 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741720.2|wormbase:W05H7.4a|dip:DIP-24700N|ensemblmetazoa:W05H7.4a.1(transcript)|ensemblmetazoa:WBGene00021047(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|uniprotkb:O02174(identity)|wormbase:WBGene00021047(identity) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 30|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:R0h2ws5KoHLO1xjsdYiNFhPwqWM6239 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 intact-crc:6637E0A1247C236A|rigid:vdD5zHofHZ1xU4+3mET5uhSsLxo false - sufficient binding region:467-522 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A6ZJ46 intact:EBI-2421103 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 - psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:g5ec62_caeel(display_short)|psi-mi:EBI-2421103(display_long)|uniprotkb:Y17G7B.19(orf name)|uniprotkb:CELE_Y17G7B.19(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543723|imex:IM-18681-860 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) uniprotkb:G5EC62(uniprot-removed-ac)|uniprotkb:G5EC62(identity)|wormbase:WBGene00012470(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 rogid:js7pRxptaiyw8zfUMVCwprOVH5Q6239 intact-crc:726B98D8DE12229B|rigid:TBFd9pzlapQtwliVRp0hAHIVHCI false sufficient binding region:467-522 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MYM0 uniprotkb:A6ZJ46 intact:EBI-320339|ensemblmetazoa:Y39B6A.46.1 intact:EBI-6535222|ensemblmetazoa:F49E2.2c.1 psi-mi:q8mym0_caeel(display_long)|uniprotkb:ztf-20(gene name)|psi-mi:ztf-20(display_short)|uniprotkb:CELE_Y39B6A.46(orf name)|uniprotkb:Y39B6A.46(orf name) psi-mi:a6zj46_caeel(display_long)|uniprotkb:CELE_F49E2.2(orf name)|uniprotkb:F49E2.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543738|imex:IM-18681-861 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741651.1|wormbase:Y39B6A.46|ensemblmetazoa:WBGene00012702(gene)|ensemblmetazoa:Y39B6A.46.1(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|dip:DIP-25414N|uniprotkb:Q8MYM0(identity)|wormbase:WBGene00012702(identity) ensemblmetazoa:WBGene00009886(gene)|ensemblmetazoa:F49E2.2c.1(transcript)|interpro:IPR001452(Src homology-3)|refseq:NP_001123147.1|wormbase:F49E2.2c|interpro:IPR036028|uniprotkb:A6ZJ46(identity)|wormbase:WBGene00009886(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:a1XdUJZOJw/E97gHCUOGw+vZT3I6239 rogid:zVauLSSk+4tMgUbIBg5AoAiw0D46239 intact-crc:27E7C61FE1226E73|rigid:YqwXlxHU6z9aHNOxew8DiHnOblY false - sufficient binding region:467-522 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22387 uniprotkb:C4ALD5 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 intact:EBI-6543757|ensemblmetazoa:F55C7.7i.1 psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:c4ald5_caeel(display_long)|uniprotkb:F55C7.7(orf name)|uniprotkb:unc-73(gene name)|psi-mi:unc-73(display_short)|uniprotkb:CELE_F55C7.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543753|imex:IM-18681-862 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) ensemblmetazoa:F55C7.7i.1(transcript)|ensemblmetazoa:WBGene00006805(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0002119"(nematode larval development)|go:"GO:0005737"(cytoplasm)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018991"(oviposition)|go:"GO:0030424"(axon)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0036194"(muscle cell projection)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048808"(male genitalia morphogenesis)|go:"GO:1905815"(regulation of dorsal/ventral axon guidance)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_001249517.1|wormbase:F55C7.7i|interpro:IPR035899|interpro:IPR036028|interpro:IPR036865|uniprotkb:C4ALD5(identity)|wormbase:WBGene00006805(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 32|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 rogid:RRKBzFdWk8zkAfctOr9H9FnVC+46239 intact-crc:108DC77BA0CAE86C|rigid:w6lF1g/LYFO9KYD3BAbw1geUku4 false - sufficient binding region:1575-1636 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:C4ALD5 uniprotkb:P34568 intact:EBI-6543757|ensemblmetazoa:F55C7.7i.1 intact:EBI-327767|uniprotkb:Q5CZ49|ensemblmetazoa:T16H12.5a.1 psi-mi:c4ald5_caeel(display_long)|uniprotkb:F55C7.7(orf name)|uniprotkb:unc-73(gene name)|psi-mi:unc-73(display_short)|uniprotkb:CELE_F55C7.7(orf name) psi-mi:bat43_caeel(display_long)|uniprotkb:T16H12.5(orf name)|uniprotkb:HIB homolog(gene name synonym)|uniprotkb:bath-43(gene name)|psi-mi:bath-43(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543770|imex:IM-18681-863 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F55C7.7i.1(transcript)|ensemblmetazoa:WBGene00006805(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0002119"(nematode larval development)|go:"GO:0005737"(cytoplasm)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018991"(oviposition)|go:"GO:0030424"(axon)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0036194"(muscle cell projection)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048808"(male genitalia morphogenesis)|go:"GO:1905815"(regulation of dorsal/ventral axon guidance)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_001249517.1|wormbase:F55C7.7i|interpro:IPR035899|interpro:IPR036028|interpro:IPR036865|uniprotkb:C4ALD5(identity)|wormbase:WBGene00006805(identity) refseq:NP_001022764.1|refseq:NP_001022765.1|wormbase:T16H12.5a|wormbase:T16H12.5b|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|reactome:R-CEL-5632684|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|ensemblmetazoa:T16H12.5a.1(transcript)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|ensemblmetazoa:WBGene00011815(gene)|go:"GO:0005634"(nucleus)|uniprotkb:P34568(identity)|wormbase:WBGene00011815(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RRKBzFdWk8zkAfctOr9H9FnVC+46239 rogid:jdL1h8z7Z9QycJYQHIVzF66EkL86239 intact-crc:00A2C40C0166201D|rigid:FZolxXsU82xtokN8qwHQ081VjRk false sufficient binding region:1575-1636 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10457 uniprotkb:Q21004 intact:EBI-311886|ensemblmetazoa:B0286.3.1 intact:EBI-6543789|ensemblmetazoa:F58G6.1.1|ensemblmetazoa:F58G6.1.2 psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:q21004_caeel(display_long)|uniprotkb:F58G6.1(orf name)|uniprotkb:amph-1(gene name)|psi-mi:amph-1(display_short)|uniprotkb:CELE_F58G6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543785|imex:IM-18681-864 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) reactome:R-CEL-8856828|ensemblmetazoa:F58G6.1.1(transcript)|ensemblmetazoa:F58G6.1.2(transcript)|ensemblmetazoa:WBGene00010272(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051647"(nucleus localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0060990"(lipid tube assembly involved in organelle fission)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR004148(BAR)|refseq:NP_501711.1|wormbase:F58G6.1|interpro:IPR027267|interpro:IPR036028|reactome:R-CEL-6798695|uniprotkb:Q21004(identity)|wormbase:WBGene00010272(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 rogid:3HqwfrDOg19aSbRdWM7IrXUdETU6239 intact-crc:436241B35DDB929F|rigid:C+fgE0MjyVp2unWFHAiPQelGBWU false - sufficient binding region:401-461 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECU7 uniprotkb:Q21004 intact:EBI-2414388|intact:EBI-6543806|intact:EBI-2915965|uniprotkb:B2CXX6|uniprotkb:B2CXX7|uniprotkb:B2CXX9|uniprotkb:B5U8L4|uniprotkb:G5EC66|uniprotkb:G5EF64|uniprotkb:Q5FC74|ensemblmetazoa:T24H10.7a.1|ensemblmetazoa:T24H10.7b.1 intact:EBI-6543789|ensemblmetazoa:F58G6.1.1|ensemblmetazoa:F58G6.1.2 psi-mi:jun_caeel(display_long)|uniprotkb:jun-1(gene name)|psi-mi:jun-1(display_short)|uniprotkb:T24H10.7(orf name) psi-mi:q21004_caeel(display_long)|uniprotkb:F58G6.1(orf name)|uniprotkb:amph-1(gene name)|psi-mi:amph-1(display_short)|uniprotkb:CELE_F58G6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543802|imex:IM-18681-865 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NAN3(uniprot-removed-ac)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|refseq:NP_001022366.1|refseq:NP_001022368.1|refseq:NP_001122643.1|refseq:NP_001129827.1|wormbase:T24H10.7b|wormbase:T24H10.7c|wormbase:T24H10.7d|wormbase:T24H10.7e|wormbase:T24H10.7a|ensemblmetazoa:WBGene00012005(gene)|reactome:R-CEL-2559580|reactome:R-CEL-2871796|reactome:R-CEL-450341|refseq:NP_001022367.1|ensemblmetazoa:T24H10.7a.1(transcript)|ensemblmetazoa:T24H10.7b.1(transcript)|ensemblmetazoa:WBGene00012005(gene)|ensemblmetazoa:WBGene00012005(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042594"(response to starvation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0051726"(regulation of cell cycle)|uniprotkb:B2CXX6(identity)|wormbase:WBGene00012005(identity) reactome:R-CEL-8856828|ensemblmetazoa:F58G6.1.1(transcript)|ensemblmetazoa:F58G6.1.2(transcript)|ensemblmetazoa:WBGene00010272(gene)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051647"(nucleus localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0060990"(lipid tube assembly involved in organelle fission)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR004148(BAR)|refseq:NP_501711.1|wormbase:F58G6.1|interpro:IPR027267|interpro:IPR036028|reactome:R-CEL-6798695|uniprotkb:Q21004(identity)|wormbase:WBGene00010272(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/06/09 rogid:lMKeB1IuDOGwd5AIYTBiK0H4uCQ6239 rogid:3HqwfrDOg19aSbRdWM7IrXUdETU6239 intact-crc:8DFF59F77DF73D90|rigid:z2VN90JdGW63kVUaFyO0S3b1JxY false - sufficient binding region:401-461 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20398 uniprotkb:O76572 intact:EBI-322716|ensemblmetazoa:F44D12.1a.1 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 psi-mi:q20398_caeel(display_long)|uniprotkb:magu-4(gene name)|psi-mi:magu-4(display_short)|uniprotkb:F44D12.1(orf name)|uniprotkb:CELE_F44D12.1(orf name) psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543819|imex:IM-18681-866 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F44D12.1a.1(transcript)|ensemblmetazoa:WBGene00009678(gene)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR027417|interpro:IPR035537|interpro:IPR036028|interpro:IPR036034|wormbase:F44D12.1a|dip:DIP-26684N|reactome:R-CEL-9013420|reactome:R-CEL-9013424|uniprotkb:Q20398(identity)|wormbase:WBGene00009678(identity) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:yKOYpRav6wvmreffAp7m8Igoz7w6239 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 intact-crc:48BB17ED7150B83C|rigid:DsRBm8Met+fPk9sBK81hdgzEbqY false - sufficient binding region:532-589 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76572 uniprotkb:Q21648 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543834|imex:IM-18681-867 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 intact-crc:B46FBE0ED1DF86CC|rigid:6UEXaNu7Zv0tGqo6se+4Eej7U9w false sufficient binding region:532-589 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76572 uniprotkb:Q4VNJ8 intact:EBI-6535465|ensemblmetazoa:K07D4.7b.1 intact:EBI-2918529 psi-mi:o76572_caeel(display_long)|uniprotkb:ephx-1(gene name)|psi-mi:ephx-1(display_short)|uniprotkb:CELE_K07D4.7(orf name)|uniprotkb:K07D4.7(orf name) psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543849|imex:IM-18681-868 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K07D4.7b.1(transcript)|ensemblmetazoa:WBGene00019487(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_494707.1|wormbase:K07D4.7b|interpro:IPR035899|interpro:IPR036028|uniprotkb:O76572(identity)|wormbase:WBGene00019487(identity) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ykGeawEkBTY4ukQAAr+ckfEN23k6239 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 intact-crc:A18CF3EF9DE8A5C8|rigid:FOpAn+atZ2Bti+vE3Ww9dNSPo38 false sufficient binding region:532-589 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XUS7-2 uniprotkb:P34707 intact:EBI-12629275|ensemblmetazoa:K08E3.3a.1 intact:EBI-319213|uniprotkb:Q8MPW2|uniprotkb:Q8MPW3|ensemblmetazoa:T19E7.2a.1 psi-mi:q9xus7-2(display_long)|uniprotkb:toca-2(gene name)|psi-mi:toca-2(display_short)|uniprotkb:K08E3.3(orf name) psi-mi:skn1_caeel(display_long)|uniprotkb:skn-1(gene name)|psi-mi:skn-1(display_short)|uniprotkb:T19E7.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543864|imex:IM-18681-869 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6535801(isoform-parent)|ensemblmetazoa:K08E3.3a.1(transcript)|ensemblmetazoa:WBGene00010663(gene)|uniprotkb:Q9U3B8(identity)|wormbase:WBGene00010663(identity) ensemblmetazoa:T19E7.2a.1(transcript)|ensemblmetazoa:WBGene00004804(gene)|go:"GO:0000303"(response to superoxide)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006417"(regulation of translation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048382"(mesendoderm development)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:1900409"(positive regulation of cellular response to oxidative stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901562"(response to paraquat)|go:"GO:1905804"(positive regulation of cellular response to manganese ion)|refseq:NP_741404.1|refseq:NP_741405.1|refseq:NP_741406.1|wormbase:T19E7.2a|wormbase:T19E7.2b|wormbase:T19E7.2c|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:1SKN|interpro:IPR004826(Maf transcription factor)|reactome:R-CEL-8932339|uniprotkb:P34707(identity)|wormbase:WBGene00004804(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:q8SSrrDQKHiHNPSBWBHPUrgGZjg6239 rogid:N+x6NUg+thGahkVDU78sb9jHYuM6239 intact-crc:2C6A2517584DAC5A|rigid:jO26i4GQlyd6xN7qhcWw8WG6NI0 false sufficient binding region:550-608 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NA61 uniprotkb:Q9XUS7-2 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 intact:EBI-12629275|ensemblmetazoa:K08E3.3a.1 psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:q9xus7-2(display_long)|uniprotkb:toca-2(gene name)|psi-mi:toca-2(display_short)|uniprotkb:K08E3.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543879|imex:IM-18681-870 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) intact:EBI-6535801(isoform-parent)|ensemblmetazoa:K08E3.3a.1(transcript)|ensemblmetazoa:WBGene00010663(gene)|uniprotkb:Q9U3B8(identity)|wormbase:WBGene00010663(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 rogid:q8SSrrDQKHiHNPSBWBHPUrgGZjg6239 intact-crc:FAAF4D68A8FE91B7|rigid:qV0Vq2ZNZZseu63Z6SmCeoNN4Ww false - sufficient binding region:550-608 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4S034 uniprotkb:Q17795 intact:EBI-6535822|ensemblmetazoa:K10B3.10a.1 intact:EBI-2316131|ensemblmetazoa:C07G1.4a.1 psi-mi:g4s034_caeel(display_long)|uniprotkb:K10B3.10(orf name)|uniprotkb:spc-1(gene name)|psi-mi:spc-1(display_short)|uniprotkb:CELE_K10B3.10(orf name) psi-mi:q17795_caeel(display_long)|uniprotkb:wsp-1(gene name)|psi-mi:wsp-1(display_short)|uniprotkb:CELE_C07G1.4(orf name)|uniprotkb:C07G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543894|imex:IM-18681-871 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:K10B3.10a.1(transcript)|ensemblmetazoa:WBGene00004951(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051693"(actin filament capping)|interpro:IPR035825|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|wormbase:K10B3.10a|interpro:IPR018159|interpro:IPR018247|refseq:NP_001256999.1|interpro:IPR036028|uniprotkb:G4S034(identity)|wormbase:WBGene00004951(identity) refseq:NP_741459.2|wormbase:C07G1.4a|interpro:IPR000697(EVH1)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR033927|interpro:IPR036936|interpro:IPR030214|ensemblmetazoa:C07G1.4a.1(transcript)|ensemblmetazoa:WBGene00006957(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|uniprotkb:Q17795(identity)|wormbase:WBGene00006957(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:98NuGykSfInnIVkxQiACjB/V5r06239 rogid:YBTDOwM+8a5vUAiihYM6ezASlGY6239 intact-crc:24D6C89EF18B0085|rigid:vayzZj+jjqd/S3xees4iHdbSbjg false sufficient binding region:986-1041 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MYM0 uniprotkb:G4S034 intact:EBI-320339|ensemblmetazoa:Y39B6A.46.1 intact:EBI-6535822|ensemblmetazoa:K10B3.10a.1 psi-mi:q8mym0_caeel(display_long)|uniprotkb:ztf-20(gene name)|psi-mi:ztf-20(display_short)|uniprotkb:CELE_Y39B6A.46(orf name)|uniprotkb:Y39B6A.46(orf name) psi-mi:g4s034_caeel(display_long)|uniprotkb:K10B3.10(orf name)|uniprotkb:spc-1(gene name)|psi-mi:spc-1(display_short)|uniprotkb:CELE_K10B3.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543909|imex:IM-18681-872 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741651.1|wormbase:Y39B6A.46|ensemblmetazoa:WBGene00012702(gene)|ensemblmetazoa:Y39B6A.46.1(transcript)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|dip:DIP-25414N|uniprotkb:Q8MYM0(identity)|wormbase:WBGene00012702(identity) ensemblmetazoa:K10B3.10a.1(transcript)|ensemblmetazoa:WBGene00004951(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051693"(actin filament capping)|interpro:IPR035825|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|wormbase:K10B3.10a|interpro:IPR018159|interpro:IPR018247|refseq:NP_001256999.1|interpro:IPR036028|uniprotkb:G4S034(identity)|wormbase:WBGene00004951(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:a1XdUJZOJw/E97gHCUOGw+vZT3I6239 rogid:98NuGykSfInnIVkxQiACjB/V5r06239 intact-crc:B6EF89AB520FD733|rigid:kjIuG0JC1Op0Pr8x4lCx0JInxyM false - sufficient binding region:986-1041 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17795 uniprotkb:Q18501 intact:EBI-2316131|ensemblmetazoa:C07G1.4a.1 intact:EBI-6535972|ensemblmetazoa:C36E8.4.1 psi-mi:q17795_caeel(display_long)|uniprotkb:wsp-1(gene name)|psi-mi:wsp-1(display_short)|uniprotkb:CELE_C07G1.4(orf name)|uniprotkb:C07G1.4(orf name) psi-mi:q18501_caeel(display_long)|uniprotkb:CELE_C36E8.4(orf name)|uniprotkb:C36E8.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543924|imex:IM-18681-873 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741459.2|wormbase:C07G1.4a|interpro:IPR000697(EVH1)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR033927|interpro:IPR036936|interpro:IPR030214|ensemblmetazoa:C07G1.4a.1(transcript)|ensemblmetazoa:WBGene00006957(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|uniprotkb:Q17795(identity)|wormbase:WBGene00006957(identity) ensemblmetazoa:C36E8.4.1(transcript)|ensemblmetazoa:WBGene00007983(gene)|interpro:IPR027267|interpro:IPR031160|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_497805.2|wormbase:C36E8.4|interpro:IPR036028|uniprotkb:Q18501(identity)|wormbase:WBGene00007983(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:YBTDOwM+8a5vUAiihYM6ezASlGY6239 rogid:7ad27IrJILlSTyYLMCV6AMEp1IA6239 intact-crc:3F5ECBB1E8BB18EF|rigid:bpubN12NxkSs/B4HWVrGfR5wm7w false - sufficient binding region:484-548 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18501 uniprotkb:P32085 intact:EBI-6535972|ensemblmetazoa:C36E8.4.1 intact:EBI-313377|ensemblmetazoa:T20B12.2.1 psi-mi:q18501_caeel(display_long)|uniprotkb:CELE_C36E8.4(orf name)|uniprotkb:C36E8.4(orf name) psi-mi:tbp_caeel(display_long)|uniprotkb:tbp-1(gene name)|psi-mi:tbp-1(display_short)|uniprotkb:tbp(gene name synonym)|uniprotkb:T20B12.2(orf name)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543939|imex:IM-18681-874 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C36E8.4.1(transcript)|ensemblmetazoa:WBGene00007983(gene)|interpro:IPR027267|interpro:IPR031160|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_497805.2|wormbase:C36E8.4|interpro:IPR036028|uniprotkb:Q18501(identity)|wormbase:WBGene00007983(identity) refseq:NP_498635.1|wormbase:T20B12.2|ensemblmetazoa:T20B12.2.1(transcript)|ensemblmetazoa:WBGene00006542(gene)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0140223"(general transcription initiation factor activity)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|go:"GO:0006352"(DNA-templated transcription, initiation)|reactome:R-CEL-6807505|reactome:R-CEL-674695|reactome:R-CEL-73776|reactome:R-CEL-73779|reactome:R-CEL-75953|reactome:R-CEL-76042|reactome:R-CEL-9018519|dip:DIP-26447N|reactome:R-CEL-73772|uniprotkb:P32085(identity)|wormbase:WBGene00006542(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:7ad27IrJILlSTyYLMCV6AMEp1IA6239 rogid:o7s313h1WbgESEEeKW35tAqWX2k6239 intact-crc:22B45B09EAE5E9C5|rigid:kKuhI/mNC5z4+tMrWZN9M77b0e0 false sufficient binding region:484-548 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BIF4 uniprotkb:Q18501 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 intact:EBI-6535972|ensemblmetazoa:C36E8.4.1 psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:q18501_caeel(display_long)|uniprotkb:CELE_C36E8.4(orf name)|uniprotkb:C36E8.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543954|imex:IM-18681-875 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) ensemblmetazoa:C36E8.4.1(transcript)|ensemblmetazoa:WBGene00007983(gene)|interpro:IPR027267|interpro:IPR031160|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|refseq:NP_497805.2|wormbase:C36E8.4|interpro:IPR036028|uniprotkb:Q18501(identity)|wormbase:WBGene00007983(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/09 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 rogid:7ad27IrJILlSTyYLMCV6AMEp1IA6239 intact-crc:6F3EA02AF2CE75F5|rigid:ggTROr1Grdf2vMoE4u3a5fLC6Qo false - sufficient binding region:484-548 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10457 uniprotkb:A0A0K3AV08 intact:EBI-311886|ensemblmetazoa:B0286.3.1 intact:EBI-322350|uniprotkb:A0A0K3AS83|uniprotkb:H2KYR3|uniprotkb:Q8T7Z0|ensemblmetazoa:K11D12.10c.1 psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:mlk1_caeel(display_long)|uniprotkb:mlk-1(gene name)|psi-mi:mlk-1(display_short)|uniprotkb:Mixed lineage kinase homolog 1(gene name synonym)|uniprotkb:K11D12.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543969|imex:IM-18681-876 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) wormbase:K11D12.10a|refseq:NP_001300151.1|wormbase:K11D12.10b|wormbase:K11D12.10c|wormbase:K11D12.10d|refseq:NP_001300152.1|refseq:NP_741536.1|refseq:NP_741537.1|ensemblmetazoa:K11D12.10c.1(transcript)|ensemblmetazoa:WBGene00003374(gene)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031103"(axon regeneration)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0046688"(response to copper ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036028|dip:DIP-25180N|uniprotkb:Q8T7Z0(identity)|wormbase:WBGene00003374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/03/30 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 rogid:v6Obv6pOk7skWee5xEaNZkz9csw6239 intact-crc:84DCB557C5CCC598|rigid:R4qXSNafM8cDTy4M6sQBW3KHAYE false - sufficient binding region:67-129 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17583 uniprotkb:A0A0K3AV08 intact:EBI-313389|uniprotkb:Q9XZQ5|ensemblmetazoa:C09H6.2a.1 intact:EBI-322350|uniprotkb:A0A0K3AS83|uniprotkb:H2KYR3|uniprotkb:Q8T7Z0|ensemblmetazoa:K11D12.10c.1 psi-mi:lin10_caeel(display_long)|uniprotkb:lin-10(gene name)|psi-mi:lin-10(display_short)|uniprotkb:C09H6.2(orf name)|uniprotkb:Abnormal cell lineage protein 10(gene name synonym) psi-mi:mlk1_caeel(display_long)|uniprotkb:mlk-1(gene name)|psi-mi:mlk-1(display_short)|uniprotkb:Mixed lineage kinase homolog 1(gene name synonym)|uniprotkb:K11D12.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543984|imex:IM-18681-877 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020996.1|refseq:NP_492226.2|wormbase:C09H6.2a|wormbase:C09H6.2b|ensemblmetazoa:C09H6.2a.1(transcript)|ensemblmetazoa:WBGene00002999(gene)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0008104"(protein localization)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:1902946"(protein localization to early endosome)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|go:"GO:1905852"(positive regulation of backward locomotion)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|go:"GO:0030140"(trans-Golgi network transport vesicle)|reactome:R-CEL-212676|dip:DIP-24889N|uniprotkb:O17583(identity)|wormbase:WBGene00002999(identity) wormbase:K11D12.10a|refseq:NP_001300151.1|wormbase:K11D12.10b|wormbase:K11D12.10c|wormbase:K11D12.10d|refseq:NP_001300152.1|refseq:NP_741536.1|refseq:NP_741537.1|ensemblmetazoa:K11D12.10c.1(transcript)|ensemblmetazoa:WBGene00003374(gene)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031103"(axon regeneration)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0046688"(response to copper ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036028|dip:DIP-25180N|uniprotkb:Q8T7Z0(identity)|wormbase:WBGene00003374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/03/30 rogid:Jf79hZqq2OhYFyo9bRA/bwZ2Cy06239 rogid:v6Obv6pOk7skWee5xEaNZkz9csw6239 intact-crc:92EBF69C69F4DD18|rigid:Q1QHuuVr85FMXQufl1wDKJfwiQA false - sufficient binding region:67-129 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NA61 uniprotkb:A0A0K3AV08 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 intact:EBI-322350|uniprotkb:A0A0K3AS83|uniprotkb:H2KYR3|uniprotkb:Q8T7Z0|ensemblmetazoa:K11D12.10c.1 psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:mlk1_caeel(display_long)|uniprotkb:mlk-1(gene name)|psi-mi:mlk-1(display_short)|uniprotkb:Mixed lineage kinase homolog 1(gene name synonym)|uniprotkb:K11D12.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6543999|imex:IM-18681-878 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) wormbase:K11D12.10a|refseq:NP_001300151.1|wormbase:K11D12.10b|wormbase:K11D12.10c|wormbase:K11D12.10d|refseq:NP_001300152.1|refseq:NP_741536.1|refseq:NP_741537.1|ensemblmetazoa:K11D12.10c.1(transcript)|ensemblmetazoa:WBGene00003374(gene)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031103"(axon regeneration)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0046688"(response to copper ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036028|dip:DIP-25180N|uniprotkb:Q8T7Z0(identity)|wormbase:WBGene00003374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/03/30 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 rogid:v6Obv6pOk7skWee5xEaNZkz9csw6239 intact-crc:EC38CA53CD529FD8|rigid:CGOsByFZeoV7eWFNbGlUbMwm2Qk false - sufficient binding region:67-129 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E3W735 uniprotkb:O44820 intact:EBI-6536005|ensemblmetazoa:K11E4.4b.1 intact:EBI-318098|ensemblmetazoa:F52C6.3.1 psi-mi:e3w735_caeel(display_long)|uniprotkb:K11E4.4(orf name)|uniprotkb:pix-1(gene name)|psi-mi:pix-1(display_short)|uniprotkb:CELE_K11E4.4(orf name) psi-mi:o44820_caeel(display_long)|uniprotkb:F52C6.3(orf name)|uniprotkb:CELE_F52C6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544014|imex:IM-18681-879 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040039"(inductive cell migration)|ensemblmetazoa:K11E4.4b.1(transcript)|ensemblmetazoa:WBGene00010776(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0016301"(kinase activity)|go:"GO:0030056"(hemidesmosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001257228.1|wormbase:K11E4.4b|interpro:IPR035899|interpro:IPR036028|uniprotkb:E3W735(identity)|wormbase:WBGene00010776(identity) refseq:NP_494127.2|wormbase:F52C6.3|ensemblmetazoa:F52C6.3.1(transcript)|ensemblmetazoa:WBGene00018660(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|go:"GO:0016567"(protein ubiquitination)|dip:DIP-24316N|uniprotkb:O44820(identity)|wormbase:WBGene00018660(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ZkXL8YaZ0pnMS0ZZJIQv3V//uSE6239 rogid:QuJ7/jGkBkfQqUUmrAJ8OuPtJUo6239 intact-crc:403540EDB0735A18|rigid:QftaipfexxBelIZ17BDGH4W48nA false sufficient binding region:188-243 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10457 uniprotkb:O17972 intact:EBI-311886|ensemblmetazoa:B0286.3.1 intact:EBI-6544033|ensemblmetazoa:M28.7.1|uniprotkb:Q21570 psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:nphp1_caeel(display_long)|uniprotkb:nphp-1(gene name)|psi-mi:nphp-1(display_short)|uniprotkb:Nephronophthisis homolog(gene name synonym)|uniprotkb:M28.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544029|imex:IM-18681-880 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) ensemblmetazoa:M28.7.1(transcript)|ensemblmetazoa:WBGene00010898(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034607"(turning behavior involved in mating)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR039687|interpro:IPR001452(Src homology-3)|refseq:NP_496298.1|wormbase:M28.7|interpro:IPR036028|uniprotkb:O17972(identity)|wormbase:WBGene00010898(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 rogid:Em7WkZND7ST6YlL4lhw4g8sP0BE6239 intact-crc:CE5994FBEB989EEE|rigid:z4qPd1OQeBhwkO/lBVzJ2DmyV7k false - sufficient binding region:218-274 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17972 uniprotkb:Q17744 intact:EBI-6544033|ensemblmetazoa:M28.7.1|uniprotkb:Q21570 intact:EBI-2315966|ensemblmetazoa:F43B10.1c.1 psi-mi:nphp1_caeel(display_long)|uniprotkb:nphp-1(gene name)|psi-mi:nphp-1(display_short)|uniprotkb:Nephronophthisis homolog(gene name synonym)|uniprotkb:M28.7(orf name) psi-mi:q17744_caeel(display_long)|uniprotkb:CELE_F43B10.1(orf name)|uniprotkb:F43B10.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544046|imex:IM-18681-881 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M28.7.1(transcript)|ensemblmetazoa:WBGene00010898(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034607"(turning behavior involved in mating)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR039687|interpro:IPR001452(Src homology-3)|refseq:NP_496298.1|wormbase:M28.7|interpro:IPR036028|uniprotkb:O17972(identity)|wormbase:WBGene00010898(identity) interpro:IPR011992(EF-Hand type)|interpro:IPR018247|wormbase:F43B10.1c|refseq:NP_001257277.1|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR041534|ensemblmetazoa:F43B10.1c.1(transcript)|ensemblmetazoa:WBGene00018373(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|uniprotkb:Q17744(identity)|wormbase:WBGene00015548(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Em7WkZND7ST6YlL4lhw4g8sP0BE6239 rogid:yBu4mQzQP54tuujYZMZhAIVmquE6239 intact-crc:B45AAE4A7D115349|rigid:WN4zMTLnzCNfOwj8jVptQmfmNHM false sufficient binding region:218-274 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17972 uniprotkb:Q17865 intact:EBI-6544033|ensemblmetazoa:M28.7.1|uniprotkb:Q21570 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:nphp1_caeel(display_long)|uniprotkb:nphp-1(gene name)|psi-mi:nphp-1(display_short)|uniprotkb:Nephronophthisis homolog(gene name synonym)|uniprotkb:M28.7(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544061|imex:IM-18681-882 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M28.7.1(transcript)|ensemblmetazoa:WBGene00010898(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034607"(turning behavior involved in mating)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR039687|interpro:IPR001452(Src homology-3)|refseq:NP_496298.1|wormbase:M28.7|interpro:IPR036028|uniprotkb:O17972(identity)|wormbase:WBGene00010898(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Em7WkZND7ST6YlL4lhw4g8sP0BE6239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:8EE406546400B8D4|rigid:jwK29YdnLgY+/e6eHjebaUCuyYw false sufficient binding region:218-274 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17972 uniprotkb:P46582 intact:EBI-6544033|ensemblmetazoa:M28.7.1|uniprotkb:Q21570 intact:EBI-319789|ensemblmetazoa:C34E10.8.1 psi-mi:nphp1_caeel(display_long)|uniprotkb:nphp-1(gene name)|psi-mi:nphp-1(display_short)|uniprotkb:Nephronophthisis homolog(gene name synonym)|uniprotkb:M28.7(orf name) psi-mi:sumv1_caeel(display_long)|uniprotkb:sumv-1(gene name)|psi-mi:sumv-1(display_short)|uniprotkb:Suppressor of synthetic multivulva protein 1(gene name synonym)|uniprotkb:C34E10.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544076|imex:IM-18681-883 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M28.7.1(transcript)|ensemblmetazoa:WBGene00010898(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034607"(turning behavior involved in mating)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR039687|interpro:IPR001452(Src homology-3)|refseq:NP_496298.1|wormbase:M28.7|interpro:IPR036028|uniprotkb:O17972(identity)|wormbase:WBGene00010898(identity) refseq:NP_498116.2|wormbase:C34E10.8|interpro:IPR025927|ensemblmetazoa:C34E10.8.1(transcript)|ensemblmetazoa:WBGene00016409(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|uniprotkb:P46582(identity)|wormbase:WBGene00016409(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Em7WkZND7ST6YlL4lhw4g8sP0BE6239 rogid:TfmDnsXbiby7iv1VQ3Zmg0TM5uA6239 intact-crc:9FEEAF19D9213BA2|rigid:tU1oYY7LffDCoKUIDD5ve6gaUtI false sufficient binding region:218-274 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17972 uniprotkb:P34400 intact:EBI-6544033|ensemblmetazoa:M28.7.1|uniprotkb:Q21570 intact:EBI-2315872|uniprotkb:P34386|uniprotkb:P34403|uniprotkb:Q7JQ80|uniprotkb:Q8WT53|ensemblmetazoa:F10E9.6c.1|ensemblmetazoa:F10E9.6c.2 psi-mi:nphp1_caeel(display_long)|uniprotkb:nphp-1(gene name)|psi-mi:nphp-1(display_short)|uniprotkb:Nephronophthisis homolog(gene name synonym)|uniprotkb:M28.7(orf name) psi-mi:mig10_caeel(display_long)|uniprotkb:mig-10(gene name)|psi-mi:mig-10(display_short)|uniprotkb:F10E9.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544091|imex:IM-18681-884 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M28.7.1(transcript)|ensemblmetazoa:WBGene00010898(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034607"(turning behavior involved in mating)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR039687|interpro:IPR001452(Src homology-3)|refseq:NP_496298.1|wormbase:M28.7|interpro:IPR036028|uniprotkb:O17972(identity)|wormbase:WBGene00010898(identity) refseq:NP_001021248.1|refseq:NP_498821.2|refseq:NP_498822.2|wormbase:F10E9.6a|wormbase:F10E9.6b|wormbase:F10E9.6c|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000159(Ras-association)|interpro:IPR029071|reactome:R-CEL-354192|interpro:IPR039664|interpro:IPR039665|reactome:R-CEL-354194|reactome:R-CEL-5674135|ensemblmetazoa:F10E9.6c.1(transcript)|ensemblmetazoa:F10E9.6c.2(transcript)|ensemblmetazoa:WBGene00003243(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0007165"(signal transduction)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018991"(oviposition)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031941"(filamentous actin)|go:"GO:0032584"(growth cone membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0043204"(perikaryon)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099523"(presynaptic cytosol)|uniprotkb:P34400(identity)|wormbase:WBGene00003243(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Em7WkZND7ST6YlL4lhw4g8sP0BE6239 rogid:qni0Ph9hE7m4FAxHa2yRYfjO0qY6239 intact-crc:C27BA8C48749E4E3|rigid:No9ZARuqqiZArxv3Xq56QnZSKr0 false sufficient binding region:218-274 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZE3 uniprotkb:O17972 intact:EBI-6544106|ensemblmetazoa:F49F1.6a.1 intact:EBI-6544033|ensemblmetazoa:M28.7.1|uniprotkb:Q21570 psi-mi:q9gze3_caeel(display_long)|uniprotkb:mul-1(gene name)|psi-mi:mul-1(display_short)|uniprotkb:CELE_F49F1.6(orf name)|uniprotkb:F49F1.6(orf name) psi-mi:nphp1_caeel(display_long)|uniprotkb:nphp-1(gene name)|psi-mi:nphp-1(display_short)|uniprotkb:Nephronophthisis homolog(gene name synonym)|uniprotkb:M28.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544108|imex:IM-18681-885 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F49F1.6a.1(transcript)|ensemblmetazoa:WBGene00018646(gene)|wormbase:F49F1.6a|interpro:IPR003582(Metridin-like ShK toxin)|refseq:NP_500487.2|uniprotkb:Q9GZE3(identity)|wormbase:WBGene00018646(identity) ensemblmetazoa:M28.7.1(transcript)|ensemblmetazoa:WBGene00010898(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034607"(turning behavior involved in mating)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR039687|interpro:IPR001452(Src homology-3)|refseq:NP_496298.1|wormbase:M28.7|interpro:IPR036028|uniprotkb:O17972(identity)|wormbase:WBGene00010898(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qoNOGo7ZzEJfsemh0XyqsoucXac6239 rogid:Em7WkZND7ST6YlL4lhw4g8sP0BE6239 intact-crc:ACA97C3C51FE8767|rigid:NQwz5+Q96DIBEPURXiVWf62DTGc false - sufficient binding region:218-274 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O61887 uniprotkb:O17972 intact:EBI-6544127|ensemblmetazoa:K10C9.3.1 intact:EBI-6544033|ensemblmetazoa:M28.7.1|uniprotkb:Q21570 psi-mi:rnst2_caeel(display_long)|uniprotkb:rnst-2(gene name)|psi-mi:rnst-2(display_short)|uniprotkb:RNase T2 rnst-2(gene name synonym)|uniprotkb:K10C9.3(orf name) psi-mi:nphp1_caeel(display_long)|uniprotkb:nphp-1(gene name)|psi-mi:nphp-1(display_short)|uniprotkb:Nephronophthisis homolog(gene name synonym)|uniprotkb:M28.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544123|imex:IM-18681-886 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|interpro:IPR033697|ensemblmetazoa:K10C9.3.1(transcript)|ensemblmetazoa:WBGene00019624(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0033897"(ribonuclease T2 activity)|interpro:IPR033130|interpro:IPR001568(Ribonuclease T2)|interpro:IPR018188|refseq:NP_503370.1|wormbase:K10C9.3|interpro:IPR036430|uniprotkb:O61887(identity)|wormbase:WBGene00019624(identity) ensemblmetazoa:M28.7.1(transcript)|ensemblmetazoa:WBGene00010898(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034607"(turning behavior involved in mating)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR039687|interpro:IPR001452(Src homology-3)|refseq:NP_496298.1|wormbase:M28.7|interpro:IPR036028|uniprotkb:O17972(identity)|wormbase:WBGene00010898(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KWCcekqOCQIEh//bs40M3Ad29Mg6239 rogid:Em7WkZND7ST6YlL4lhw4g8sP0BE6239 intact-crc:200C00A110B80920|rigid:HJV5Ols43svMT4WeZtwDJgw/wLg false - sufficient binding region:218-274 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17972 uniprotkb:O02174 intact:EBI-6544033|ensemblmetazoa:M28.7.1|uniprotkb:Q21570 intact:EBI-2315779|ensemblmetazoa:W05H7.4a.1 psi-mi:nphp1_caeel(display_long)|uniprotkb:nphp-1(gene name)|psi-mi:nphp-1(display_short)|uniprotkb:Nephronophthisis homolog(gene name synonym)|uniprotkb:M28.7(orf name) psi-mi:o02174_caeel(display_long)|uniprotkb:zfp-3(gene name)|psi-mi:zfp-3(display_short)|uniprotkb:CELE_W05H7.4(orf name)|uniprotkb:W05H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544140|imex:IM-18681-887 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M28.7.1(transcript)|ensemblmetazoa:WBGene00010898(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034607"(turning behavior involved in mating)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR039687|interpro:IPR001452(Src homology-3)|refseq:NP_496298.1|wormbase:M28.7|interpro:IPR036028|uniprotkb:O17972(identity)|wormbase:WBGene00010898(identity) refseq:NP_741720.2|wormbase:W05H7.4a|dip:DIP-24700N|ensemblmetazoa:W05H7.4a.1(transcript)|ensemblmetazoa:WBGene00021047(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|uniprotkb:O02174(identity)|wormbase:WBGene00021047(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Em7WkZND7ST6YlL4lhw4g8sP0BE6239 rogid:R0h2ws5KoHLO1xjsdYiNFhPwqWM6239 intact-crc:07DED136C3B8F1FD|rigid:ARIcaPQsca6qKLQ3PO9zuyLMwm8 false sufficient binding region:218-274 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EGI2 uniprotkb:O17972 intact:EBI-6541649|ensemblmetazoa:Y38C1BA.2a.1 intact:EBI-6544033|ensemblmetazoa:M28.7.1|uniprotkb:Q21570 psi-mi:g5egi2_caeel(display_long)|uniprotkb:Y38C1BA.2(orf name)|uniprotkb:snn-1(gene name)|psi-mi:snn-1(display_short)|uniprotkb:syn(gene name synonym)|uniprotkb:CELE_Y38C1BA.2(orf name) psi-mi:nphp1_caeel(display_long)|uniprotkb:nphp-1(gene name)|psi-mi:nphp-1(display_short)|uniprotkb:Nephronophthisis homolog(gene name synonym)|uniprotkb:M28.7(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544155|imex:IM-18681-888 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004913(gene)|ensemblmetazoa:Y38C1BA.2a.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0046872"(metal ion binding)|refseq:NP_741327.1|wormbase:Y38C1BA.2a|interpro:IPR001359(Synapsin)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020897|interpro:IPR020898|uniprotkb:G5EGI2(identity)|wormbase:WBGene00004913(identity) ensemblmetazoa:M28.7.1(transcript)|ensemblmetazoa:WBGene00010898(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034607"(turning behavior involved in mating)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR039687|interpro:IPR001452(Src homology-3)|refseq:NP_496298.1|wormbase:M28.7|interpro:IPR036028|uniprotkb:O17972(identity)|wormbase:WBGene00010898(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MH29+7Es7PNDOIE7j5XuTk9zSVY6239 rogid:Em7WkZND7ST6YlL4lhw4g8sP0BE6239 intact-crc:58DC5F5717485F67|rigid:aqxs4Xlms1SqsGjYp8kUqbyzGds false - sufficient binding region:218-274 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17972 uniprotkb:Q9NA61 intact:EBI-6544033|ensemblmetazoa:M28.7.1|uniprotkb:Q21570 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 psi-mi:nphp1_caeel(display_long)|uniprotkb:nphp-1(gene name)|psi-mi:nphp-1(display_short)|uniprotkb:Nephronophthisis homolog(gene name synonym)|uniprotkb:M28.7(orf name) psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544170|imex:IM-18681-889 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M28.7.1(transcript)|ensemblmetazoa:WBGene00010898(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034607"(turning behavior involved in mating)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR039687|interpro:IPR001452(Src homology-3)|refseq:NP_496298.1|wormbase:M28.7|interpro:IPR036028|uniprotkb:O17972(identity)|wormbase:WBGene00010898(identity) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Em7WkZND7ST6YlL4lhw4g8sP0BE6239 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 intact-crc:608DC6CBCF1EC853|rigid:uNVUUGxcCKISKAp4uSAU97NsSs8 false sufficient binding region:218-274 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17972 uniprotkb:Q94418 intact:EBI-6544033|ensemblmetazoa:M28.7.1|uniprotkb:Q21570 intact:EBI-593113|ensemblmetazoa:ZK858.2.1 psi-mi:nphp1_caeel(display_long)|uniprotkb:nphp-1(gene name)|psi-mi:nphp-1(display_short)|uniprotkb:Nephronophthisis homolog(gene name synonym)|uniprotkb:M28.7(orf name) psi-mi:q94418_caeel(display_long)|uniprotkb:CELE_ZK858.2(orf name)|uniprotkb:ZK858.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544185|imex:IM-18681-890 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M28.7.1(transcript)|ensemblmetazoa:WBGene00010898(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034607"(turning behavior involved in mating)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR039687|interpro:IPR001452(Src homology-3)|refseq:NP_496298.1|wormbase:M28.7|interpro:IPR036028|uniprotkb:O17972(identity)|wormbase:WBGene00010898(identity) refseq:NP_492447.1|wormbase:ZK858.2|ensemblmetazoa:WBGene00014116(gene)|ensemblmetazoa:ZK858.2.1(transcript)|uniprotkb:Q94418(identity)|wormbase:WBGene00014116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Em7WkZND7ST6YlL4lhw4g8sP0BE6239 rogid:Hd/z2Kak3QHyR3gRPGcH61lG9Ho6239 intact-crc:D7149B25C47BC026|rigid:kb9aM5yEIPjm/yxd+bN8r7TsYJI false sufficient binding region:218-274 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q11181 uniprotkb:P03949 intact:EBI-2316016|uniprotkb:Q8T3F3|uniprotkb:Q8T3F4|uniprotkb:Q8T3F5|ensemblmetazoa:C05D10.4b.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:ypc4_caeel(display_long)|uniprotkb:C05D10.4(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544200|imex:IM-18681-891 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498323.2|refseq:NP_498324.2|refseq:NP_741170.1|wormbase:C05D10.4a|wormbase:C05D10.4b|wormbase:C05D10.4c|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|ensemblmetazoa:C05D10.4b.1(transcript)|ensemblmetazoa:WBGene00015480(gene)|uniprotkb:Q11181(identity)|wormbase:WBGene00015480(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:msS16ZOpmue9+9+to7VFLPE1TM86239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:68B8B227850C928A|rigid:bldjfU8RtePV/VJk/5Pngl49DUQ false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:Q17795 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-2316131|ensemblmetazoa:C07G1.4a.1 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:q17795_caeel(display_long)|uniprotkb:wsp-1(gene name)|psi-mi:wsp-1(display_short)|uniprotkb:CELE_C07G1.4(orf name)|uniprotkb:C07G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544215|imex:IM-18681-892 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) refseq:NP_741459.2|wormbase:C07G1.4a|interpro:IPR000697(EVH1)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR033927|interpro:IPR036936|interpro:IPR030214|ensemblmetazoa:C07G1.4a.1(transcript)|ensemblmetazoa:WBGene00006957(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|uniprotkb:Q17795(identity)|wormbase:WBGene00006957(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:YBTDOwM+8a5vUAiihYM6ezASlGY6239 intact-crc:0F809A1C761FCAC2|rigid:+LSXpUboefBdNpiLZxEMoOkczms false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18225 uniprotkb:P03949 intact:EBI-6542980|ensemblmetazoa:C26E6.2.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:flh2_caeel(display_long)|uniprotkb:C26E6.2(orf name)|uniprotkb:flh-2(gene name)|psi-mi:flh-2(display_short) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544230|imex:IM-18681-893 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C26E6.2.1(transcript)|ensemblmetazoa:WBGene00016138(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR007588(Zinc finger, FLYWCH-type)|refseq:NP_498049.2|wormbase:C26E6.2|uniprotkb:Q18225(identity)|wormbase:WBGene00016138(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:H53A9H3CbM2l/HLncgbQ6QgA8Fg6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:25990CB3CEBA684C|rigid:uXVyQ7/ZN5YJ6Vjhhqmz48uGzZc false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:Q18953 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-318539|uniprotkb:B5U8M4|ensemblmetazoa:D1054.13a.1 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:spcs_caeel(display_long)|uniprotkb:secs-1(gene name)|psi-mi:secs-1(display_short)|uniprotkb:D1054.13(orf name)|uniprotkb:"Selenocysteinyl-tRNA(Sec) synthase"(gene name synonym)|uniprotkb:"Sep-tRNA:Sec-tRNA synthase"(gene name synonym)|uniprotkb:UGA suppressor tRNA-associated protein homolog(gene name synonym)|uniprotkb:Selenocysteine synthase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544246|imex:IM-18681-894 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) refseq:NP_001129887.1|refseq:NP_505761.1|wormbase:D1054.13a|wormbase:D1054.13b|ensemblmetazoa:D1054.13a.1(transcript)|ensemblmetazoa:WBGene00008379(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0001514"(selenocysteine incorporation)|go:"GO:0005737"(cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process")|go:"GO:0098621"(phosphoseryl-selenocysteinyl-tRNA selenium transferase activity)|interpro:IPR008829(Soluble liver antigen/liver pancreas antigen)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019872|mint:Q18953|dip:DIP-26886N|uniprotkb:Q18953(identity)|wormbase:WBGene00008379(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 33|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:J5TkQ+CIecgTuXqiIG7tsdEntlE6239 intact-crc:7C771FA50A483C65|rigid:Dz9FCKQTkPQv/G4S+LqRjDouaZQ false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 intact:EBI-6544261 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 - psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:e2iub2_caeel(display_short)|psi-mi:EBI-6544261(display_long)|uniprotkb:egl-9.4c(gene name)|psi-mi:egl-9.4c(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544263|imex:IM-18681-895 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) uniprotkb:E2IUB2(uniprot-removed-ac)|uniprotkb:E2IUB2(identity)|wormbase:WBGene00001178(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:vfYsuFRpiksvZtgFcOhSp7YRmy06239 intact-crc:0262140A393F6CD5|rigid:7ASl0spQkFJ0ISaFO9eF+zc/s2E false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20398 uniprotkb:P03949 intact:EBI-322716|ensemblmetazoa:F44D12.1a.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:q20398_caeel(display_long)|uniprotkb:magu-4(gene name)|psi-mi:magu-4(display_short)|uniprotkb:F44D12.1(orf name)|uniprotkb:CELE_F44D12.1(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544278|imex:IM-18681-896 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F44D12.1a.1(transcript)|ensemblmetazoa:WBGene00009678(gene)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR027417|interpro:IPR035537|interpro:IPR036028|interpro:IPR036034|wormbase:F44D12.1a|dip:DIP-26684N|reactome:R-CEL-9013420|reactome:R-CEL-9013424|uniprotkb:Q20398(identity)|wormbase:WBGene00009678(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/04/06 rogid:yKOYpRav6wvmreffAp7m8Igoz7w6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:2D956737E4E1B7E9|rigid:leH3JsMiX4qW2Wfb4GC8/lrxrO0 false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22227 uniprotkb:P03949 intact:EBI-316403|ensemblmetazoa:T05C12.6a.1|intact:EBI-2315994|intact:EBI-2924320|uniprotkb:G5EC49|uniprotkb:O76471|uniprotkb:Q95ZQ0 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:mig5_caeel(display_long)|uniprotkb:Abnormal cell migration protein 5(gene name synonym)|uniprotkb:T05C12.6(orf name)|uniprotkb:mig-5(gene name)|psi-mi:mig-5(display_short) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544293|imex:IM-18681-897 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-5663220|refseq:NP_001022316.1|wormbase:T05C12.6a|ensemblmetazoa:T05C12.6a.1(transcript)|ensemblmetazoa:WBGene00003241(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001709"(cell fate determination)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0016477"(cell migration)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030054"(cell junction)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040039"(inductive cell migration)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060069"(Wnt signaling pathway, regulating spindle positioning)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060573"(cell fate specification involved in pattern specification)|go:"GO:0070986"(left/right axis specification)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|go:"GO:0048730"(epidermis morphogenesis)|refseq:NP_001022317.1|refseq:NP_001022318.1|wormbase:T05C12.6b|wormbase:T05C12.6c|dip:DIP-27038N|reactome:R-CEL-201688|reactome:R-CEL-4086400|reactome:R-CEL-4641258|reactome:R-CEL-5099900|reactome:R-CEL-2028269|reactome:R-CEL-4641262|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:G5EC49(identity)|wormbase:WBGene00003241(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:Pp8SAvLL8oifjCuQDA+XKc3EON86239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:C8CF8F83061DA224|rigid:GKH3CaaRvgJAURlj5FOVzauYVe0 false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC72 uniprotkb:P03949 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544308|imex:IM-18681-898 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 20|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:5ECB9ECE29C7791E|rigid:8fJhiAeC+Q9DsvmC+nuuCmXG1TA false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:Q95QA6 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544323|imex:IM-18681-899 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 23|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 intact-crc:AEF134DE699BF4E1|rigid:9fJggb5W+YRBatyLvXt2JIKm2cM false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02174 uniprotkb:P03949 intact:EBI-2315779|ensemblmetazoa:W05H7.4a.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:o02174_caeel(display_long)|uniprotkb:zfp-3(gene name)|psi-mi:zfp-3(display_short)|uniprotkb:CELE_W05H7.4(orf name)|uniprotkb:W05H7.4(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544338|imex:IM-18681-900 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741720.2|wormbase:W05H7.4a|dip:DIP-24700N|ensemblmetazoa:W05H7.4a.1(transcript)|ensemblmetazoa:WBGene00021047(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|uniprotkb:O02174(identity)|wormbase:WBGene00021047(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:R0h2ws5KoHLO1xjsdYiNFhPwqWM6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:88EF6E8C369D76C3|rigid:F6fKNmwAxJ6k8YzIJmmLvunmbcI false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U304 uniprotkb:P03949 intact:EBI-329038|ensemblmetazoa:Y106G6D.7.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:q9u304_caeel(display_long)|uniprotkb:rbm-12(gene name)|psi-mi:rbm-12(display_short)|uniprotkb:CELE_Y106G6D.7(orf name)|uniprotkb:Y106G6D.7(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544353|imex:IM-18681-901 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492671.1|wormbase:Y106G6D.7|dip:DIP-26480N|ensemblmetazoa:WBGene00013703(gene)|ensemblmetazoa:Y106G6D.7.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-CEL-72163|uniprotkb:Q9U304(identity)|wormbase:WBGene00013703(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:/8MJkmHgCyjvgK0ZmDnklHVfJrw6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:EF35002EBAEB8E21|rigid:YqvixiN9GpG93dC27BMnXXrZ604 false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EF87 uniprotkb:P03949 intact:EBI-311928|ensemblmetazoa:Y113G7B.23a.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:g5ef87_caeel(display_long)|uniprotkb:swsn-1(gene name)|psi-mi:swsn-1(display_short)|uniprotkb:psa-1(gene name synonym)|uniprotkb:Y113G7B.23(orf name)|uniprotkb:CELE_Y113G7B.23(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544368|imex:IM-18681-902 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9U2W6(uniprot-removed-ac)|refseq:NP_001256906.1|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|ensemblmetazoa:WBGene00004203(gene)|ensemblmetazoa:Y113G7B.23a.1(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002119"(nematode larval development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR032448|interpro:IPR032451|wormbase:Y113G7B.23a|interpro:IPR036388|interpro:IPR038044|uniprotkb:G5EF87(identity)|wormbase:WBGene00004203(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LXe8rVw0BSmSfyXr2pY+NPIHLTs6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:1BF3D7883A2B4EDC|rigid:jlnYnWzLa63X2/U+qFsAc4l/1vE false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8I4E2 uniprotkb:P03949 intact:EBI-4325777|uniprotkb:D3NQ98|uniprotkb:J7SA60|uniprotkb:Q8I4E1|uniprotkb:Q9XXG2|uniprotkb:Q9XXG3|ensemblmetazoa:Y37A1B.2c.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:lst4_caeel(display_long)|uniprotkb:lst-4(gene name)|psi-mi:lst-4(display_short)|uniprotkb:Lateral signaling target protein 4(gene name synonym)|uniprotkb:Y37A1B.2(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544383|imex:IM-18681-903 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036871|interpro:IPR027267|interpro:IPR036028|wormbase:Y37A1B.2d|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|reactome:R-CEL-8856828|refseq:NP_502693.2|wormbase:Y37A1B.2a|wormbase:Y37A1B.2b|wormbase:Y37A1B.2c|wormbase:Y37A1B.2e|wormbase:Y37A1B.2f|refseq:NP_001255779.1|refseq:NP_001263811.1|refseq:NP_502694.1|refseq:NP_502695.2|refseq:NP_872090.1|reactome:R-CEL-432722|go:"GO:0032009"(early phagosome)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045335"(phagocytic vesicle)|ensemblmetazoa:WBGene00003086(gene)|ensemblmetazoa:Y37A1B.2c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0090389"(phagosome-lysosome fusion involved in apoptotic cell clearance)|go:"GO:0097194"(execution phase of apoptosis) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:NqGhrxQdIIT2DDOgu+/swsZFniQ6239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:ABC2AF953A5201C0|rigid:WRS0Jkbd87Xc7hsQwR7aen2dM10 false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:A8XQ35 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-6542385|ensemblmetazoa:Y53H1A.1b.1 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:a8xq35_caeel(display_long)|uniprotkb:Y53H1A.1(orf name)|uniprotkb:rsy-1(gene name)|psi-mi:rsy-1(display_short)|uniprotkb:CELE_Y53H1A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544398|imex:IM-18681-904 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) ensemblmetazoa:WBGene00013177(gene)|ensemblmetazoa:Y53H1A.1b.1(transcript)|go:"GO:0016607"(nuclear speck)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0005634"(nucleus)|interpro:IPR031937|refseq:NP_001122545.2|wormbase:Y53H1A.1b|uniprotkb:A8XQ35(identity)|wormbase:WBGene00013177(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 14|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:buN2kigAdUvAYZ2AhwHTaAMEjSo6239 intact-crc:989A49D1A8587497|rigid:TiO0tXfgRdhk4lX1UGowFR7sLNs false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:G5ED33 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544413|imex:IM-18681-905 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:0DD647CC978618EF|rigid:Corif4Vwr0s7Uf42DZs1k1LrUgs false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03949 uniprotkb:Q4VNJ8 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 intact:EBI-2918529 psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544428|imex:IM-18681-906 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 intact-crc:3288504A607766C2|rigid:6Ov/6Knz+KPw9xCpa0JHUyekKK0 false sufficient binding region:118-187 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BIF4 uniprotkb:P03949 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 intact:EBI-2315883|uniprotkb:Q9U3A2|uniprotkb:Q9U3A3|ensemblmetazoa:M79.1a.1 psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:abl1_caeel(display_long)|uniprotkb:abl-1(gene name)|psi-mi:abl-1(display_short)|uniprotkb:M79.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544443|imex:IM-18681-907 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) refseq:NP_509777.2|refseq:NP_509778.2|refseq:NP_509779.2|wormbase:M79.1a|wormbase:M79.1b|wormbase:M79.1c|reactome:R-CEL-525793|reactome:R-CEL-9013149|dip:DIP-48409N|reactome:R-CEL-8939236|reactome:R-CEL-2029482|reactome:R-CEL-5663213|ensemblmetazoa:M79.1a.1(transcript)|ensemblmetazoa:WBGene00000018(gene)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|uniprotkb:P03949(identity)|wormbase:WBGene00000018(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 22|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/09 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 rogid:abKCOI+387FyCmkWTqxVxNKonjw6239 intact-crc:928E4D8B3D7A207E|rigid:tkBtUmE/Kc/aqMw4sii+v7wdgt0 false - sufficient binding region:118-187 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBH3 uniprotkb:P39055 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544458|imex:IM-18681-908 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:C87817C2BA92E7F3|rigid:07fhzIwVC0Fp/y3+42aIos8Qu9M false sufficient binding region:826-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBH3 uniprotkb:Q17865 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544473|imex:IM-18681-909 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:4D095B3BD85CF8C6|rigid:nBBANpH/jsK/PQc0FJPS1xs6XZg false sufficient binding region:826-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QQ9 uniprotkb:G5EBH3 intact:EBI-2317344|ensemblmetazoa:C49H3.6a.1 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 psi-mi:q95qq9_caeel(display_long)|uniprotkb:C49H3.6(orf name)|uniprotkb:CELE_C49H3.6(orf name) psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544488|imex:IM-18681-910 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501316.2|wormbase:C49H3.6a|interpro:IPR019131|ensemblmetazoa:C49H3.6a.1(transcript)|ensemblmetazoa:WBGene00016792(gene)|go:"GO:0005737"(cytoplasm)|uniprotkb:Q95QQ9(identity)|wormbase:WBGene00016792(identity) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eHT6KUXkocreuSpbjuHpYT+s+tQ6239 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 intact-crc:0A9D1D0FC9A995EF|rigid:qGc3HgzY8zVwUH71RBdRcCqGyIE false - sufficient binding region:826-879 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O61701 uniprotkb:G5EBH3 intact:EBI-6537266 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 psi-mi:o61701_caeel(display_long)|uniprotkb:cyk-1(gene name)|psi-mi:cyk-1(display_short) psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544503|imex:IM-18681-911 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003779"(actin binding)|go:"GO:0016043"(cellular component organization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|uniprotkb:O61701(identity)|wormbase:WBGene00000872(identity) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:3tZm/rdSqLAK4eIpP1J9faYAo7w6239 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 intact-crc:C2B4E0A669B9C086|rigid:KQKsYj625qzjid5c43IZ+aPrMrs false - sufficient binding region:826-879 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1XFY2 uniprotkb:G5EBH3 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544518|imex:IM-18681-912 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 intact-crc:6E61AEBAC9100EDB|rigid:5oGcFsgRG9bbK5u+NqH83sXCwes false - sufficient binding region:826-879 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21648 uniprotkb:G5EBH3 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544533|imex:IM-18681-913 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 34|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 intact-crc:329289017D89A9F6|rigid:y6jnOzlQQfnU4c1SEcUZ5FnMEUQ false - sufficient binding region:826-879 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBH3 uniprotkb:G5EC72 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544548|imex:IM-18681-914 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 28|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:AEC4DEA2CC168423|rigid:qbKD39kCWDSOiN560lc1sJNfmYk false sufficient binding region:826-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:G5EBH3 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544563|imex:IM-18681-915 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 intact-crc:4DD3CFBD7C1A1C43|rigid:5qSohQ093sOUfTG81KgcZ8zk6yo false - sufficient binding region:826-879 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U304 uniprotkb:G5EBH3 intact:EBI-329038|ensemblmetazoa:Y106G6D.7.1 intact:EBI-6536467|ensemblmetazoa:R31.1d.1 psi-mi:q9u304_caeel(display_long)|uniprotkb:rbm-12(gene name)|psi-mi:rbm-12(display_short)|uniprotkb:CELE_Y106G6D.7(orf name)|uniprotkb:Y106G6D.7(orf name) psi-mi:g5ebh3_caeel(display_long)|uniprotkb:R31.1(orf name)|uniprotkb:sma-1(gene name)|psi-mi:sma-1(display_short)|uniprotkb:CELE_R31.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544578|imex:IM-18681-916 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492671.1|wormbase:Y106G6D.7|dip:DIP-26480N|ensemblmetazoa:WBGene00013703(gene)|ensemblmetazoa:Y106G6D.7.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-CEL-72163|uniprotkb:Q9U304(identity)|wormbase:WBGene00013703(identity) go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0035150"(regulation of tube size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0051693"(actin filament capping)|ensemblmetazoa:R31.1d.1(transcript)|ensemblmetazoa:WBGene00004855(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018159|refseq:NP_001256383.1|wormbase:R31.1d|interpro:IPR036028|interpro:IPR036872|interpro:IPR041681|uniprotkb:G5EBH3(identity)|wormbase:WBGene00004855(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:/8MJkmHgCyjvgK0ZmDnklHVfJrw6239 rogid:G/ccS/pnWZpRuLH5HpV2NOpfdVc6239 intact-crc:977ADC45355C4AC4|rigid:Di+VbqFvBZdHtQR3GAWeW2Mba4k false - sufficient binding region:826-879 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22070 uniprotkb:Q10457 intact:EBI-6544593|ensemblmetazoa:T01E8.3.1 intact:EBI-311886|ensemblmetazoa:B0286.3.1 psi-mi:plcg_caeel(display_long)|uniprotkb:Phosphoinositide phospholipase C-gamma plc-3(gene name synonym)|uniprotkb:plc-3(gene name)|psi-mi:plc-3(display_short)|uniprotkb:Phospholipase C-gamma plc-3(gene name synonym)|uniprotkb:T01E8.3(orf name) psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544595|imex:IM-18681-917 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T01E8.3.1(transcript)|ensemblmetazoa:WBGene00004038(gene)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0030431"(sleep)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|reactome:R-CEL-5621480|reactome:R-CEL-1169408|reactome:R-CEL-186763|wormbase:T01E8.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR000980(SH2 motif)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001452(Src homology-3)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR016279(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma)|interpro:IPR017946|refseq:NP_496205.2|reactome:R-CEL-114604|reactome:R-CEL-1855204|reactome:R-CEL-202433|reactome:R-CEL-5607764|interpro:IPR035023|interpro:IPR035024|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q22070(identity)|wormbase:WBGene00004038(identity) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:u1FmRq+SyHtwF4rKv5P2ONYCb5M6239 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 intact-crc:ED14777B2EE3D9C4|rigid:GRJKO7j/Y1cUs0g/IqJ1Dl2sZKk false sufficient binding region:784-838 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22070 uniprotkb:Q9NA61 intact:EBI-6544593|ensemblmetazoa:T01E8.3.1 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 psi-mi:plcg_caeel(display_long)|uniprotkb:Phosphoinositide phospholipase C-gamma plc-3(gene name synonym)|uniprotkb:plc-3(gene name)|psi-mi:plc-3(display_short)|uniprotkb:Phospholipase C-gamma plc-3(gene name synonym)|uniprotkb:T01E8.3(orf name) psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544610|imex:IM-18681-918 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T01E8.3.1(transcript)|ensemblmetazoa:WBGene00004038(gene)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0030431"(sleep)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|reactome:R-CEL-5621480|reactome:R-CEL-1169408|reactome:R-CEL-186763|wormbase:T01E8.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR000980(SH2 motif)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001452(Src homology-3)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR016279(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma)|interpro:IPR017946|refseq:NP_496205.2|reactome:R-CEL-114604|reactome:R-CEL-1855204|reactome:R-CEL-202433|reactome:R-CEL-5607764|interpro:IPR035023|interpro:IPR035024|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q22070(identity)|wormbase:WBGene00004038(identity) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:u1FmRq+SyHtwF4rKv5P2ONYCb5M6239 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 intact-crc:1A69C41D729082A0|rigid:EmbzlmazVN1GxojPhMROPNUrWqU false sufficient binding region:784-838 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17865 uniprotkb:Q8MPT2 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544625|imex:IM-18681-919 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:4EA5E01640871B84|rigid:b0Gdo8BRjGKl1LhS/L7iDI2h4wg false - sufficient binding region:418-475(IPR001452) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MPT2 intact:EBI-6544644 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 intact:EBI-6516384 psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:ebi-6516384(display_short)|psi-mi:EBI-6544644(display_long) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544640|imex:IM-18681-920 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) wormbase:WBGene00015881(identity)|intact:EBI-6516384(identity) - - no-uniprot-update: figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 - intact-crc:2BB76E66E8940B61 false sufficient binding region:418-475(IPR001452) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MPT2 uniprotkb:Q65ZJ1 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 intact:EBI-6460396|ensemblmetazoa:C56E6.3b.1 psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:q65zj1_caeel(display_long)|uniprotkb:C56E6.3(orf name)|uniprotkb:toe-2(gene name)|psi-mi:toe-2(display_short)|uniprotkb:CELE_C56E6.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544658|imex:IM-18681-921 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) ensemblmetazoa:C56E6.3b.1(transcript)|ensemblmetazoa:WBGene00016971(gene)|go:"GO:0016301"(kinase activity)|refseq:NP_001022043.1|wormbase:C56E6.3b|interpro:IPR036388|uniprotkb:Q65ZJ1(identity)|wormbase:WBGene00016971(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 rogid:Bd6MaTCPnGoHXzu2IqsJGGRca7w6239 intact-crc:8624A51E6E698164|rigid:OTGF5QV53eUvP2r8ZtuluotBszQ false sufficient binding region:418-475(IPR001452) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9TYS3 uniprotkb:Q8MPT2 intact:EBI-313731|ensemblmetazoa:D1037.3.1|ensemblmetazoa:D1037.3.2 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:q9tys3_caeel(display_long)|uniprotkb:ftn-2(gene name)|psi-mi:ftn-2(display_short)|uniprotkb:CELE_D1037.3(orf name)|uniprotkb:D1037.3(orf name) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544673|imex:IM-18681-922 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-917937|refseq:NP_491198.1|wormbase:D1037.3|ensemblmetazoa:D1037.3.1(transcript)|ensemblmetazoa:D1037.3.2(transcript)|ensemblmetazoa:WBGene00001501(gene)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006826"(iron ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|go:"GO:0050830"(defense response to Gram-positive bacterium)|reactome:R-CEL-6798695|dip:DIP-27017N|uniprotkb:Q9TYS3(identity)|wormbase:WBGene00001501(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:p69JvmHGm4zBtZlWiY8Jqj8155I6239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:AA3CC976242B454C|rigid:7CMWcc6i1GknnmVMzPiYR+dq0tg false - sufficient binding region:418-475(IPR001452) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01299 uniprotkb:Q8MPT2 intact:EBI-2006306|ensemblmetazoa:F09C8.2.1 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:o01299_caeel(display_long)|uniprotkb:F09C8.2(orf name)|uniprotkb:CELE_F09C8.2(orf name) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544688|imex:IM-18681-923 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_510635.2|wormbase:F09C8.2|interpro:IPR039884|ensemblmetazoa:F09C8.2.1(transcript)|ensemblmetazoa:WBGene00008622(gene)|uniprotkb:O01299(identity)|wormbase:WBGene00008622(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4slc5ODejK3YgC912WmTzPHnEw46239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:3C046FD3D46CC1F8|rigid:oja6sykbIAxtgU5cXh5Qg4tc0og false - sufficient binding region:418-475(IPR001452) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MPT2 uniprotkb:Q19289 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 intact:EBI-316236|uniprotkb:Q19290|uniprotkb:Q21063|ensemblmetazoa:F10C1.2b.1 psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:ifb1_caeel(display_long)|uniprotkb:ifb-1(gene name)|psi-mi:ifb-1(display_short)|uniprotkb:F10C1.2(orf name)|uniprotkb:Intermediate filament protein B1(gene name synonym)|uniprotkb:Cel IF B1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544703|imex:IM-18681-924 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) refseq:NP_495136.1|refseq:NP_495137.1|wormbase:F10C1.2a|wormbase:F10C1.2b|reactome:R-CEL-4419969|ensemblmetazoa:F10C1.2b.1(transcript)|ensemblmetazoa:WBGene00002053(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|dip:DIP-26309N|uniprotkb:Q19289(identity)|wormbase:WBGene00002053(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 rogid:tTtvjq2kBdiUk2RWhrXUHC3+hvM6239 intact-crc:21F5C198916DE520|rigid:vUePctihz9FmaOJbttKXMUsasLc false sufficient binding region:418-475(IPR001452) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MPT2 uniprotkb:Q8I7N1 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 intact:EBI-6536830|ensemblmetazoa:F23H11.4b.1 psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:q8i7n1_caeel(display_long)|uniprotkb:CELE_F23H11.4(orf name)|uniprotkb:F23H11.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544718|imex:IM-18681-925 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) ensemblmetazoa:F23H11.4b.1(transcript)|ensemblmetazoa:WBGene00017760(gene)|refseq:NP_871688.1|wormbase:F23H11.4b|uniprotkb:Q8I7N1(identity)|wormbase:WBGene00017760(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 rogid:KGpecISk4snodX96bb3rQom2kEA6239 intact-crc:A5D4F755CFE8018E|rigid:lwvmV1ZVVF2TMpCPFZn1GH5bCwM false sufficient binding region:418-475(IPR001452) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E3W743 uniprotkb:Q8MPT2 intact:EBI-6531504|ensemblmetazoa:F29G6.3d.1|ensemblmetazoa:F29G6.3d.2|ensemblmetazoa:F29G6.3d.3|ensemblmetazoa:F29G6.3d.4|ensemblmetazoa:F29G6.3d.5|ensemblmetazoa:F29G6.3d.6|ensemblmetazoa:F29G6.3d.7|ensemblmetazoa:F29G6.3d.8 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:e3w743_caeel(display_long)|uniprotkb:CELE_F29G6.3(orf name)|uniprotkb:hpo-34(gene name)|psi-mi:hpo-34(display_short)|uniprotkb:F29G6.3(orf name) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544733|imex:IM-18681-926 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F29G6.3d.1(transcript)|ensemblmetazoa:F29G6.3d.2(transcript)|ensemblmetazoa:F29G6.3d.3(transcript)|ensemblmetazoa:F29G6.3d.4(transcript)|ensemblmetazoa:F29G6.3d.5(transcript)|ensemblmetazoa:F29G6.3d.6(transcript)|ensemblmetazoa:F29G6.3d.7(transcript)|ensemblmetazoa:F29G6.3d.8(transcript)|ensemblmetazoa:WBGene00009259(gene)|refseq:NP_001257163.1|wormbase:F29G6.3d|uniprotkb:E3W743(identity)|wormbase:WBGene00009259(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 93|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:bfGOwt7f2E0y3asTS+wSWof9DUQ6239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:186DFFD975E1F96E|rigid:5oGfN04emZiKKP/hTzHs5gwQBJI false - sufficient binding region:418-475(IPR001452) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MPT2 uniprotkb:O16299 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544748|imex:IM-18681-927 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 intact-crc:11E5352BAD3E694F|rigid:Y2K1tfOJcmpZNXQGF6pUCimZtpw false sufficient binding region:418-475(IPR001452) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20177 uniprotkb:Q8MPT2 intact:EBI-325747|ensemblmetazoa:F38E9.1.1 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:q20177_caeel(display_long)|uniprotkb:F38E9.1(orf name)|uniprotkb:CELE_F38E9.1(orf name) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544763|imex:IM-18681-928 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_510673.1|wormbase:F38E9.1|ensemblmetazoa:F38E9.1.1(transcript)|ensemblmetazoa:WBGene00018184(gene)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008081"(phosphoric diester hydrolase activity)|interpro:IPR017946|interpro:IPR042158|dip:DIP-25899N|uniprotkb:Q20177(identity)|wormbase:WBGene00018184(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:0365vrSc61A665R4aWQd0t/XHNA6239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:F240E222B22A9DD5|rigid:f8JuZAnL0kKbgasVpZNz/3qBMFM false - sufficient binding region:418-475(IPR001452) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-2315690 uniprotkb:Q8MPT2 - intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:q9tzk1_caeel(display_short)|psi-mi:EBI-2315690(display_long)|uniprotkb:fkh-8(gene name)|psi-mi:fkh-8(display_short)|uniprotkb:CELE_F40H3.4(orf name)|uniprotkb:F40H3.4(orf name) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544778|imex:IM-18681-929 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9TZK1(uniprot-removed-ac)|uniprotkb:Q9TZK1(identity)|wormbase:WBGene00001440(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:IveywrdXrkscc1xpNEb9kZDkOJ06239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:4E4C9FF96C9CC1DF|rigid:EiuccaVKIIJ9oYl6Jhg2ABO2aN8 false - sufficient binding region:418-475(IPR001452) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20357 uniprotkb:Q8MPT2 intact:EBI-2317438|ensemblmetazoa:F43C9.3.1 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:q20357_caeel(display_long)|uniprotkb:hum-10(gene name)|psi-mi:hum-10(display_short)|uniprotkb:F43C9.3(orf name)|uniprotkb:CELE_F43C9.3(orf name) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544793|imex:IM-18681-930 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001609(Myosin head, motor region)|wormbase:F43C9.3|refseq:NP_508817.3|interpro:IPR027417|interpro:IPR036961|ensemblmetazoa:F43C9.3.1(transcript)|ensemblmetazoa:WBGene00018377(gene)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016459"(myosin complex)|uniprotkb:Q20357(identity)|wormbase:WBGene00018377(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ArCbroDNdRLmROesJTMrxE2tQMw6239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:E5DCC66EB9E29FF5|rigid:+tNvXJA4XR4FBPevJBhOZZJEqYM false - sufficient binding region:418-475(IPR001452) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MPT2 intact:EBI-6544812 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 intact:EBI-6516389 psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:ebi-6516389(display_short)|psi-mi:EBI-6544812(display_long) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544808|imex:IM-18681-931 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) intact:EBI-6516389(identity)|wormbase:WBGene00010490(identity) - - no-uniprot-update: figure legend:Supplementary table 3|comment:Y2H colony count - 38|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 - intact-crc:DBD3BC8E72E11F91 false sufficient binding region:418-475(IPR001452) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MPT2 uniprotkb:G5EBF5 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 intact:EBI-328046|ensemblmetazoa:T20G5.11.1 psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:g5ebf5_caeel(display_long)|uniprotkb:rde-4(gene name)|psi-mi:rde-4(display_short)|uniprotkb:T20G5.11(orf name)|uniprotkb:CELE_T20G5.11(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544826|imex:IM-18681-932 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) uniprotkb:Q22617(uniprot-removed-ac)|rcsb pdb:2LTR|rcsb pdb:2LTS|interpro:IPR014720(Double-stranded RNA-binding-like)|refseq:NP_499265.1|wormbase:T20G5.11|ensemblmetazoa:T20G5.11.1(transcript)|ensemblmetazoa:WBGene00004326(gene)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0016246"(RNA interference)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-CEL-203927|reactome:R-CEL-426486|uniprotkb:G5EBF5(identity)|wormbase:WBGene00004326(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 rogid:KP9wT0JggVuuriaDYCy0gSMvD9Y6239 intact-crc:5644DEE24F82323F|rigid:wPDagmquTfcKBCNc4/z8OpM7zbQ false sufficient binding region:418-475(IPR001452) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MPT2 uniprotkb:O02174 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 intact:EBI-2315779|ensemblmetazoa:W05H7.4a.1 psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:o02174_caeel(display_long)|uniprotkb:zfp-3(gene name)|psi-mi:zfp-3(display_short)|uniprotkb:CELE_W05H7.4(orf name)|uniprotkb:W05H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544841|imex:IM-18681-933 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) refseq:NP_741720.2|wormbase:W05H7.4a|dip:DIP-24700N|ensemblmetazoa:W05H7.4a.1(transcript)|ensemblmetazoa:WBGene00021047(gene)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|uniprotkb:O02174(identity)|wormbase:WBGene00021047(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 21|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 rogid:R0h2ws5KoHLO1xjsdYiNFhPwqWM6239 intact-crc:989DC614F55FF838|rigid:yhuT4BUa1PQTGkYFi79GnpPingM false sufficient binding region:418-475(IPR001452) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEM0 uniprotkb:Q8MPT2 intact:EBI-315855|ensemblmetazoa:Y45G5AM.1a.1|ensemblmetazoa:Y45G5AM.1a.2|uniprotkb:A0A168HAV7|uniprotkb:Q86PI7 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:nh114_caeel(display_long)|uniprotkb:Y45G5AM.1(orf name)|uniprotkb:nhr-114(gene name)|psi-mi:nhr-114(display_short) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544856|imex:IM-18681-934 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9GUI3(uniprot-removed-ac)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|refseq:NP_001024242.1|refseq:NP_001317845.1|wormbase:Y45G5AM.1a|ensemblmetazoa:WBGene00003704(gene)|ensemblmetazoa:Y45G5AM.1a.1(transcript)|ensemblmetazoa:Y45G5AM.1a.2(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0048856"(anatomical structure development)|interpro:IPR035500|wormbase:Y45G5AM.1d|uniprotkb:G5EEM0(identity)|wormbase:WBGene00003704(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:r3xk9wxqtrEVL4eq4F4FzaJPtto6239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:53491220C77C9F8B|rigid:LGujuHT0W8WfjKC6K1xj8SO584E false - sufficient binding region:418-475(IPR001452) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4G4 uniprotkb:Q8MPT2 intact:EBI-2315681|uniprotkb:Q95Y43|uniprotkb:Q9GPV1|ensemblmetazoa:Y71F9B.10a.1 intact:EBI-2315635|ensemblmetazoa:T04C9.1c.1 psi-mi:med1_caeel(display_long)|uniprotkb:sop-3(gene name)|psi-mi:sop-3(display_short)|uniprotkb:mdt-1.1(gene name synonym)|uniprotkb:Mediator complex subunit 1.1(gene name synonym)|uniprotkb:Suppressor of pal-1 protein 3(gene name synonym)|uniprotkb:Y71F9B.10(orf name) psi-mi:q8mpt2_caeel(display_long)|uniprotkb:CELE_T04C9.1(orf name)|uniprotkb:T04C9.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544871|imex:IM-18681-935 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021811.1|refseq:NP_740821.1|wormbase:Y71F9B.10a|wormbase:Y71F9B.10b|ensemblmetazoa:WBGene00004946(gene)|ensemblmetazoa:Y71F9B.10a.1(transcript)|go:"GO:0005634"(nucleus)|uniprotkb:Q9N4G4(identity)|wormbase:WBGene00004946(identity) refseq:NP_001293638.1|wormbase:T04C9.1c|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblmetazoa:T04C9.1c.1(transcript)|ensemblmetazoa:WBGene00020209(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|uniprotkb:Q8MPT2(identity)|wormbase:WBGene00020209(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 29|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KTcrkv3uyrMmaFBN+H93wvHt+5s6239 rogid:G2rigLbG8gZZmihdbTnfGmhn8Rw6239 intact-crc:9ED1F9493A07C7B2|rigid:a0tg3T4MSNSo1l4+l8vYXOJaa8c false - sufficient binding region:418-475(IPR001452) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:P39055 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544886|imex:IM-18681-936 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:C50CD67302702630|rigid:nKIiQmBBWJQ5MlaWc0V7PvBAGWs false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17795 uniprotkb:B1V8A0 intact:EBI-2316131|ensemblmetazoa:C07G1.4a.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:q17795_caeel(display_long)|uniprotkb:wsp-1(gene name)|psi-mi:wsp-1(display_short)|uniprotkb:CELE_C07G1.4(orf name)|uniprotkb:C07G1.4(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544901|imex:IM-18681-937 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741459.2|wormbase:C07G1.4a|interpro:IPR000697(EVH1)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR033927|interpro:IPR036936|interpro:IPR030214|ensemblmetazoa:C07G1.4a.1(transcript)|ensemblmetazoa:WBGene00006957(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|uniprotkb:Q17795(identity)|wormbase:WBGene00006957(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:YBTDOwM+8a5vUAiihYM6ezASlGY6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:688D1745E90C017C|rigid:PWdlg3jQlVwDmpfL1BkkkcQUIHg false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:Q19994 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-2316468|ensemblmetazoa:F34D10.4.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:q19994_caeel(display_long)|uniprotkb:F34D10.4(orf name)|uniprotkb:CELE_F34D10.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544916|imex:IM-18681-938 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) refseq:NP_497758.1|wormbase:F34D10.4|ensemblmetazoa:F34D10.4.1(transcript)|ensemblmetazoa:WBGene00009374(gene)|uniprotkb:Q19994(identity)|wormbase:WBGene00009374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:Yyp9k3/LEbiLhySq1vul5tfQN6o6239 intact-crc:1A7D2D4B25864720|rigid:IYdzBy7soSOohkmwaGgedOzRl7E false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:Q95YA9 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-6536858|ensemblmetazoa:F41G4.2a.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:q95ya9_caeel(display_long)|uniprotkb:F41G4.2(orf name)|uniprotkb:cas-1(gene name)|psi-mi:cas-1(display_short)|uniprotkb:CELE_F41G4.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544931|imex:IM-18681-939 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) interpro:IPR028417|reactome:R-CEL-6798695|ensemblmetazoa:F41G4.2a.1(transcript)|ensemblmetazoa:WBGene00000294(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR017901|wormbase:F41G4.2a|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR036222|interpro:IPR036223|interpro:IPR028419|refseq:NP_510714.1|uniprotkb:Q95YA9(identity)|wormbase:WBGene00000294(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:Wtu62Erja5FAbcy4JVr/DUWQf0w6239 intact-crc:ACC2577E74BA84CE|rigid:rcpiaoXTxMIEg2ZuIKZUZum0aFQ false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:Q1XFY2 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544946|imex:IM-18681-940 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 intact-crc:E8691D0844F6F7FD|rigid:d9qo04WIDaabLzWnpsjG590/GP0 false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86D09 uniprotkb:B1V8A0 intact:EBI-6544961|ensemblmetazoa:F46B3.17.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:q86d09_caeel(display_long)|uniprotkb:F46B3.17(orf name)|uniprotkb:col-163(gene name)|psi-mi:col-163(display_short)|uniprotkb:CELE_F46B3.17(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544963|imex:IM-18681-941 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F46B3.17.1(transcript)|ensemblmetazoa:WBGene00000736(gene)|go:"GO:0005581"(collagen trimer)|go:"GO:0016021"(integral component of membrane)|refseq:NP_001023933.1|wormbase:F46B3.17|uniprotkb:Q86D09(identity)|wormbase:WBGene00000736(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:IcsmKsY3vrHYWJVRgwHNKrWy3ss6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:C5BF12AB452A3307|rigid:y6SDhweINCwh3NTP/iLb3JDcuMs false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21648 uniprotkb:B1V8A0 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544978|imex:IM-18681-942 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:C274D24125ECA918|rigid:4eFBYeYUEhUr08sBklo8hndEtuw false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:C5NU64 uniprotkb:B1V8A0 intact:EBI-6544993|ensemblmetazoa:Y34B4A.8b.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:c5nu64_caeel(display_long)|uniprotkb:rga-8(gene name)|psi-mi:rga-8(display_short)|uniprotkb:CELE_Y34B4A.8(orf name)|uniprotkb:Y34B4A.8(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6544995|imex:IM-18681-943 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021324(gene)|ensemblmetazoa:Y34B4A.8b.1(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035020"(regulation of Rac protein signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|refseq:NP_001257018.1|wormbase:Y34B4A.8b|interpro:IPR027267|uniprotkb:C5NU64(identity)|wormbase:WBGene00021324(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:VNwNA2VRHHHMCQKsOtArDSV1JHE6239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:73F9B764353AD188|rigid:8uIDoBYu9ZWAWH7mADoFbb84V24 false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XW7 uniprotkb:B1V8A0 intact:EBI-2316700|ensemblmetazoa:Y55B1BR.2.1 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 psi-mi:q95xw7_caeel(display_long)|uniprotkb:affl-2(gene name)|psi-mi:affl-2(display_short)|uniprotkb:CELE_Y55B1BR.2(orf name)|uniprotkb:Y55B1BR.2(orf name) psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545010|imex:IM-18681-944 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497199.1|wormbase:Y55B1BR.2|interpro:IPR043640|ensemblmetazoa:WBGene00021912(gene)|ensemblmetazoa:Y55B1BR.2.1(transcript)|go:"GO:0005634"(nucleus)|uniprotkb:Q95XW7(identity)|wormbase:WBGene00021912(identity) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/11/30 rogid:JxmHFANXh2vyB+sppuHlgubtfW86239 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 intact-crc:AE3C0ED653BEE11E|rigid:789t2JBr14kqQymcJKQr3Ha35/M false - sufficient binding region:321-376 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:P19826 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-322152|ensemblmetazoa:ZC477.9d.1|uniprotkb:Q9BI32|uniprotkb:Q8MPS2|uniprotkb:Q9BI31|uniprotkb:V6CJ36|uniprotkb:V6CK82|uniprotkb:V6CLG2|uniprotkb:V6CLK1|uniprotkb:V6CLL2 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:vinc_caeel(display_long)|uniprotkb:deb-1(gene name)|psi-mi:deb-1(display_short)|uniprotkb:ZC477.9(orf name)|uniprotkb:P107B(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545025|imex:IM-18681-945 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) ensemblmetazoa:WBGene00000942(gene)|ensemblmetazoa:ZC477.9d.1(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0060279"(positive regulation of ovulation)|go:"GO:0097433"(dense body)|reactome:R-CEL-445355|reactome:R-CEL-5674135|refseq:NP_501104.2|wormbase:ZC477.9a|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR000633(Vinculin, conserved site)|refseq:NP_001293743.1|refseq:NP_001293744.1|refseq:NP_001293745.1|refseq:NP_001293746.1|refseq:NP_001293747.1|refseq:NP_501105.2|refseq:NP_741437.1|reactome:R-CEL-114608|reactome:R-CEL-6798695|interpro:IPR017997|interpro:IPR036723|wormbase:ZC477.9b|wormbase:ZC477.9c|wormbase:ZC477.9d|wormbase:ZC477.9e|wormbase:ZC477.9f|wormbase:ZC477.9g|wormbase:ZC477.9h|uniprotkb:P19826(identity)|wormbase:WBGene00000942(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:AdSmuwqJNzwZuJwyZ30NpUvUdtk6239 intact-crc:5728FC3910365280|rigid:FNF+IVP3SkkDd0ofSGFtdIqo5ko false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1V8A0 uniprotkb:Q9BIF4 intact:EBI-321745|intact:EBI-11467983|intact:EBI-6536670|uniprotkb:A5A8Q9|uniprotkb:A5A8R0|uniprotkb:O61843|uniprotkb:Q6TM46|ensemblmetazoa:T04D1.3d.1 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 psi-mi:sh3gh_caeel(display_long)|uniprotkb:unc-57(gene name)|psi-mi:unc-57(display_short)|uniprotkb:Endophilin-1 homolog(gene name synonym)|uniprotkb:Uncoordinated protein 57(gene name synonym)|uniprotkb:T04D1.3(orf name) psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545040|imex:IM-18681-946 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T04D1.3a|refseq:NP_001122513.1|wormbase:T04D1.3b|wormbase:T04D1.3c|wormbase:T04D1.3d|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|go:"GO:0031594"(neuromuscular junction)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|ensemblmetazoa:T04D1.3d.1(transcript)|ensemblmetazoa:WBGene00006791(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|reactome:R-CEL-432720|reactome:R-CEL-432722|refseq:NP_001040680.1|refseq:NP_001040681.1|refseq:NP_001122512.1|dip:DIP-25104N|reactome:R-CEL-182971|reactome:R-CEL-437239|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:A5A8Q9(identity)|wormbase:WBGene00006791(identity) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 57|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/09 rogid:J1XS0XlPh9W6vvL0PDrWWgD1q0U6239 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 intact-crc:6B3995691D87C3D0|rigid:mrejwrZBnmUuBtUwp70zD4QQgxA false sufficient binding region:321-376 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01661 uniprotkb:Q10457 intact:EBI-6537185|ensemblmetazoa:T28F2.5.1 intact:EBI-311886|ensemblmetazoa:B0286.3.1 psi-mi:o01661_caeel(display_long)|uniprotkb:T28F2.5(orf name)|uniprotkb:ccb-1(gene name)|psi-mi:ccb-1(display_short)|uniprotkb:CELE_T28F2.5(orf name) psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545055|imex:IM-18681-947 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-112308|ensemblmetazoa:T28F2.5.1(transcript)|ensemblmetazoa:WBGene00000368(gene)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0061199"(striated muscle contraction involved in embryonic body morphogenesis)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|refseq:NP_491193.2|wormbase:T28F2.5|interpro:IPR027417|interpro:IPR036028|reactome:R-CEL-422356|reactome:R-CEL-5576892|reactome:R-CEL-5576893|uniprotkb:O01661(identity)|wormbase:WBGene00000368(identity) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Khadhwx+FsP2ztUMwxF1vFtY3XI6239 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 intact-crc:5686ABF4923F2708|rigid:iPZOfs6sxeuBaW95Qe5UNCGNKcY false sufficient binding region:51-115 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01661 uniprotkb:Q9NA61 intact:EBI-6537185|ensemblmetazoa:T28F2.5.1 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 psi-mi:o01661_caeel(display_long)|uniprotkb:T28F2.5(orf name)|uniprotkb:ccb-1(gene name)|psi-mi:ccb-1(display_short)|uniprotkb:CELE_T28F2.5(orf name) psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545070|imex:IM-18681-948 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-112308|ensemblmetazoa:T28F2.5.1(transcript)|ensemblmetazoa:WBGene00000368(gene)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0061199"(striated muscle contraction involved in embryonic body morphogenesis)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|refseq:NP_491193.2|wormbase:T28F2.5|interpro:IPR027417|interpro:IPR036028|reactome:R-CEL-422356|reactome:R-CEL-5576892|reactome:R-CEL-5576893|uniprotkb:O01661(identity)|wormbase:WBGene00000368(identity) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Khadhwx+FsP2ztUMwxF1vFtY3XI6239 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 intact-crc:839887825E24FA36|rigid:zrJNcTs62JaqyMkLL0lydKHHlMg false sufficient binding region:51-115 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-2415124 uniprotkb:Q9NA61 - intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 psi-mi:o45009_caeel(display_short)|psi-mi:EBI-2415124(display_long)|uniprotkb:ccb-2(gene name)|psi-mi:ccb-2(display_short)|uniprotkb:CELE_W10C8.1(orf name)|uniprotkb:W10C8.1(orf name) psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545085|imex:IM-18681-949 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O45009(uniprot-removed-ac)|uniprotkb:O45009(identity)|wormbase:WBGene00021125(identity) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Dr0OVG9ZbHQCCsK2h+W1LRi5rbQ6239 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 intact-crc:C9113FD972C72BD1|rigid:i/TOhOXY9twCE387nd3K10Oic9U false sufficient binding region:60-130 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:Q17782 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-2914202|ensemblmetazoa:C07D10.2a.1|ensemblmetazoa:C07D10.2a.2 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:q17782_caeel(display_long)|uniprotkb:bath-44(gene name)|psi-mi:bath-44(display_short)|uniprotkb:C07D10.2(orf name)|uniprotkb:CELE_C07D10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545100|imex:IM-18681-950 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) ensemblmetazoa:C07D10.2a.1(transcript)|ensemblmetazoa:C07D10.2a.2(transcript)|ensemblmetazoa:WBGene00015567(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|refseq:NP_495550.1|wormbase:C07D10.2a|dip:DIP-25843N|uniprotkb:Q17782(identity)|wormbase:WBGene00015567(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:NeojnABlnv7ZcmcFIWnq3erZ6yM6239 intact-crc:A0AED9397EEEE4AD|rigid:YGU/9cmuZixhDhhkLuGIo/Z7ceU false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:Q17795 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-2316131|ensemblmetazoa:C07G1.4a.1 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:q17795_caeel(display_long)|uniprotkb:wsp-1(gene name)|psi-mi:wsp-1(display_short)|uniprotkb:CELE_C07G1.4(orf name)|uniprotkb:C07G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545115|imex:IM-18681-951 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) refseq:NP_741459.2|wormbase:C07G1.4a|interpro:IPR000697(EVH1)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR033927|interpro:IPR036936|interpro:IPR030214|ensemblmetazoa:C07G1.4a.1(transcript)|ensemblmetazoa:WBGene00006957(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|uniprotkb:Q17795(identity)|wormbase:WBGene00006957(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:YBTDOwM+8a5vUAiihYM6ezASlGY6239 intact-crc:7E39AA029310B914|rigid:G2JTAn1XRQCVRt1MkgX4V4PcJAw false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:Q09442 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545130|imex:IM-18681-952 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 21|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 intact-crc:2C6F42350130FC92|rigid:4QhAAf/yD0+sRAgj3VuNgyNXP7w false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QQ9 uniprotkb:Q9U2Z5 intact:EBI-2317344|ensemblmetazoa:C49H3.6a.1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:q95qq9_caeel(display_long)|uniprotkb:C49H3.6(orf name)|uniprotkb:CELE_C49H3.6(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545145|imex:IM-18681-953 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501316.2|wormbase:C49H3.6a|interpro:IPR019131|ensemblmetazoa:C49H3.6a.1(transcript)|ensemblmetazoa:WBGene00016792(gene)|go:"GO:0005737"(cytoplasm)|uniprotkb:Q95QQ9(identity)|wormbase:WBGene00016792(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eHT6KUXkocreuSpbjuHpYT+s+tQ6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:E2940517B4EC4DB6|rigid:X7EnHRHHouZsb/LmGwh5PLqI/1o false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:O61701 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-6537266 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:o61701_caeel(display_long)|uniprotkb:cyk-1(gene name)|psi-mi:cyk-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545160|imex:IM-18681-954 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) go:"GO:0003779"(actin binding)|go:"GO:0016043"(cellular component organization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|uniprotkb:O61701(identity)|wormbase:WBGene00000872(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:3tZm/rdSqLAK4eIpP1J9faYAo7w6239 intact-crc:FF36BBCBD7CFA484|rigid:RJdhfVhyqnTCvHPCiAbstHQozW4 false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:Q95YA9 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-6536858|ensemblmetazoa:F41G4.2a.1 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:q95ya9_caeel(display_long)|uniprotkb:F41G4.2(orf name)|uniprotkb:cas-1(gene name)|psi-mi:cas-1(display_short)|uniprotkb:CELE_F41G4.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545175|imex:IM-18681-955 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) interpro:IPR028417|reactome:R-CEL-6798695|ensemblmetazoa:F41G4.2a.1(transcript)|ensemblmetazoa:WBGene00000294(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR017901|wormbase:F41G4.2a|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR036222|interpro:IPR036223|interpro:IPR028419|refseq:NP_510714.1|uniprotkb:Q95YA9(identity)|wormbase:WBGene00000294(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:Wtu62Erja5FAbcy4JVr/DUWQf0w6239 intact-crc:8EC6DF218B3573B7|rigid:unAaOIlP6sq9Zf4yNIVh8WSUyHw false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1XFY2 uniprotkb:Q9U2Z5 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545190|imex:IM-18681-956 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 20|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:59C97B4F81C8C071|rigid:4I0hCOoeBuCDxb4JDa95poFW1SA false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:Q3Y407 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-2317687|uniprotkb:G4SJ35|ensemblmetazoa:F46H5.6.1 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:q3y407_caeel(display_long)|uniprotkb:grd-7(gene name)|psi-mi:grd-7(display_short)|uniprotkb:CELE_F46H5.6(orf name)|uniprotkb:F46H5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545205|imex:IM-18681-957 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) interpro:IPR007284(Ground-like region)|wormbase:F46H5.6|interpro:IPR003882(Pistil-specific extensin-like protein)|ensemblmetazoa:F46H5.6.1(transcript)|ensemblmetazoa:WBGene00001696(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007154"(cell communication)|uniprotkb:Q3Y407(identity)|wormbase:WBGene00001696(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/01/23 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:77+Ww780xL2+LUmBj5htUR6eidA6239 intact-crc:A6CFEF0B18B7C751|rigid:LyPSEQNsq9kNl8FlHpVGyU75caw false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9TYU9 uniprotkb:Q9U2Z5 intact:EBI-2317613|ensemblmetazoa:F58B6.2.1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:exc6_caeel(display_long)|uniprotkb:exc-6(gene name)|psi-mi:exc-6(display_short)|uniprotkb:inft-1(gene name synonym)|uniprotkb:F58B6.2(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545220|imex:IM-18681-958 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F58B6.2|interpro:IPR015425(Actin-binding FH2)|refseq:NP_497334.2|interpro:IPR042201|ensemblmetazoa:F58B6.2.1(transcript)|ensemblmetazoa:WBGene00019030(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031941"(filamentous actin)|go:"GO:0035150"(regulation of tube size)|go:"GO:0060562"(epithelial tube morphogenesis)|go:"GO:1904531"(positive regulation of actin filament binding)|uniprotkb:Q9TYU9(identity)|wormbase:WBGene00019030(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:oV2XrZ7bWd6qxEDMLD8J4fuVobU6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:06DB6E91DCBB8552|rigid:u5zTqWLwvuZYKpAKv311BtSZNsg false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21648 uniprotkb:Q9U2Z5 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545235|imex:IM-18681-959 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:F0D73C7594F7368C|rigid:RrkVt0rTyk6YIKK8QgEeWfIoAEM false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:F5GUF0 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-6542338|ensemblmetazoa:R06C1.3b.1 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:f5guf0_caeel(display_long)|uniprotkb:R06C1.3(orf name)|uniprotkb:wve-1(gene name)|psi-mi:wve-1(display_short)|uniprotkb:CELE_R06C1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545250|imex:IM-18681-960 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) ensemblmetazoa:R06C1.3b.1(transcript)|ensemblmetazoa:WBGene00006958(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031209"(SCAR complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|refseq:NP_001251762.1|wormbase:R06C1.3b|interpro:IPR028288|uniprotkb:F5GUF0(identity)|wormbase:WBGene00006958(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 32|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:Jmm0mWkD2Esf0E7aV7/qOpEnV906239 intact-crc:00840EB85C9EC708|rigid:AQ6EWtmyvRlgSsGDFZ3DcZYC+0k false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:Q9U2Z5 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545265|imex:IM-18681-961 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 21|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:CCE06CD4D16F58F0|rigid:K4mTgGL91PyV3jRyncyGFCLkDr0 false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:Q9N3Z0 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-315842|ensemblmetazoa:Y40C5A.1.1|ensemblmetazoa:Y40C5A.1.2 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:q9n3z0_caeel(display_long)|uniprotkb:sqst-2(gene name)|psi-mi:sqst-2(display_short)|uniprotkb:CELE_Y40C5A.1(orf name)|uniprotkb:Y40C5A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545280|imex:IM-18681-962 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) refseq:NP_501171.2|wormbase:Y40C5A.1|ensemblmetazoa:WBGene00021495(gene)|ensemblmetazoa:Y40C5A.1.1(transcript)|ensemblmetazoa:Y40C5A.1.2(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0035973"(aggrephagy)|go:"GO:0044753"(amphisome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR043145|dip:DIP-24408N|uniprotkb:Q9N3Z0(identity)|wormbase:WBGene00021495(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:+Sch+zecAfQgOh6UaE5FBHiHAHk6239 intact-crc:AF7E5DBCDD670A8D|rigid:qb7e8S8Dh7VCWZQW4eYNBU1lrrQ false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:O18195 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-313368|ensemblmetazoa:Y48E1B.1.1 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:wash1_caeel(display_long)|uniprotkb:ddl-2(gene name)|psi-mi:ddl-2(display_short)|uniprotkb:Y48E1B.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545295|imex:IM-18681-963 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) refseq:NP_496847.1|wormbase:Y48E1B.1|ensemblmetazoa:WBGene00013000(gene)|ensemblmetazoa:Y48E1B.1.1(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR021854|interpro:IPR028290|go:"GO:0043014"(alpha-tubulin binding)|dip:DIP-26697N|uniprotkb:O18195(identity)|wormbase:WBGene00013000(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 19|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:RJW5nUP6L8QcEdUDeGl4awDNlZU6239 intact-crc:1494AF495CCDE821|rigid:YcWZZSyqEoZDGwxPudFbo/vwJeg false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:Q9U2Z5 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545310|imex:IM-18681-964 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 38|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 intact-crc:678A4887E04EAB65|rigid:jcbrKwkEbYqkmHvggxD3eHco310 false - sufficient binding region:20-76 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Z5 uniprotkb:Q9BIF4 intact:EBI-317468|ensemblmetazoa:Y106G6H.14.1 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 psi-mi:q9u2z5_caeel(display_long)|uniprotkb:Y106G6H.14(orf name)|uniprotkb:CELE_Y106G6H.14(orf name) psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545325|imex:IM-18681-965 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492738.1|wormbase:Y106G6H.14|ensemblmetazoa:WBGene00013724(gene)|ensemblmetazoa:Y106G6H.14.1(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036770|reactome:R-CEL-6798695|dip:DIP-26968N|uniprotkb:Q9U2Z5(identity)|wormbase:WBGene00013724(identity) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 27|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/09 rogid:JqyS6znAqnhmuWqwMd8D487kRs06239 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 intact-crc:C236770FD84C5D45|rigid:oC0ooY1UnRCon+LUsqO+ZVmeTqM false sufficient binding region:20-76 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQE8 uniprotkb:Q9U2T9 intact:EBI-6545344|ensemblmetazoa:C06A6.2a.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:q8mqe8_caeel(display_long)|uniprotkb:CELE_C06A6.2(orf name)|uniprotkb:C06A6.2(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545340|imex:IM-18681-966 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C06A6.2a.1(transcript)|ensemblmetazoa:WBGene00015507(gene)|interpro:IPR006578(MADF)|refseq:NP_741450.2|wormbase:C06A6.2a|dip:DIP-26464N|uniprotkb:Q8MQE8(identity)|wormbase:WBGene00015507(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ipXHUTpyqbrzZGTGfWyweXCmGMo6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:F1A528E28A0712BC|rigid:NfNhr0JdAfwuNY9wnJmklMO+mr0 false - sufficient binding region:676-733 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9TZK8 uniprotkb:Q9U2T9 intact:EBI-314126|ensemblmetazoa:C36C9.1.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:q9tzk8_caeel(display_long)|uniprotkb:meg-4(gene name)|psi-mi:meg-4(display_short)|uniprotkb:C36C9.1(orf name)|uniprotkb:CELE_C36C9.1(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545357|imex:IM-18681-967 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508310.1|wormbase:C36C9.1|ensemblmetazoa:C36C9.1.1(transcript)|ensemblmetazoa:WBGene00016485(gene)|go:"GO:0036093"(germ cell proliferation)|go:"GO:0043186"(P granule)|go:"GO:0051640"(organelle localization)|go:"GO:1903863"(P granule assembly)|dip:DIP-25764N|uniprotkb:Q9TZK8(identity)|wormbase:WBGene00016485(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ayQVI+csfdpXBkKgkNxidWcSszk6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:CE4FE795C75AE660|rigid:ZOf5cNn3j27tqGIWvcIka3MOAwA false - sufficient binding region:676-733 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:O16299 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545372|imex:IM-18681-968 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 88|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 intact-crc:6462FF2980529546|rigid:bcJqmzHKDVV1D0O4nEKf+8kLjjA false sufficient binding region:676-733 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q22002 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-2316177|ensemblmetazoa:R166.1a.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:mab10_caeel(display_long)|uniprotkb:mab-10(gene name)|psi-mi:mab-10(display_short)|uniprotkb:Protein male abnormal 10(gene name synonym)|uniprotkb:R166.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545387|imex:IM-18681-969 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) interpro:IPR006989(Nab, central region)|interpro:IPR006988(Nab, N-terminal)|interpro:IPR038398|wormbase:R166.1a|refseq:NP_496268.2|interpro:IPR039040|reactome:R-CEL-9031628|ensemblmetazoa:R166.1a.1(transcript)|ensemblmetazoa:WBGene00003107(gene)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010458"(exit from mitosis)|go:"GO:0022404"(molting cycle process)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|uniprotkb:Q22002(identity)|wormbase:WBGene00003107(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:zhw1NK4weat9xTi6VsVXhJSaq+o6239 intact-crc:6017C8B3D64B2EEF|rigid:ELb/NX2+zprlYkUPvz7ploCGStg false sufficient binding region:676-733 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P53017 uniprotkb:Q9U2T9 intact:EBI-319681|ensemblmetazoa:ZK354.1.1|ensemblmetazoa:ZK354.11.1|ensemblmetazoa:ZK354.4.1|ensemblmetazoa:ZK354.5.1|ensemblmetazoa:K05F1.2.1|ensemblmetazoa:R05F9.13.1|ensemblmetazoa:R13H9.4.1|ensemblmetazoa:C33F10.9.1|ensemblmetazoa:C34F11.4.1|ensemblmetazoa:F36H12.7.1|ensemblmetazoa:ZK1248.6.1|ensemblmetazoa:F58A6.8.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:msp19_caeel(display_long)|uniprotkb:msp-19(gene name)|psi-mi:msp-19(display_short)|uniprotkb:F36H12.7(orf name)|uniprotkb:msp-31(gene name)|psi-mi:msp-31(display_short)|uniprotkb:R05F9.13(orf name)|uniprotkb:msp-40(gene name)|psi-mi:msp-40(display_short)|uniprotkb:C33F10.9(orf name)|uniprotkb:msp-45(gene name)|psi-mi:msp-45(display_short)|uniprotkb:F58A6.8(orf name)|uniprotkb:msp-50(gene name)|psi-mi:msp-50(display_short)|uniprotkb:C34F11.4(orf name)|uniprotkb:msp-51(gene name)|psi-mi:msp-51(display_short)|uniprotkb:ZK354.5(orf name)|uniprotkb:msp-53(gene name)|psi-mi:msp-53(display_short)|uniprotkb:R13H9.4(orf name)|uniprotkb:msp-59(gene name)|psi-mi:msp-59(display_short)|uniprotkb:ZK354.11(orf name)|uniprotkb:msp-64(gene name)|psi-mi:msp-64(display_short)|uniprotkb:ZK1248.6(orf name)|uniprotkb:msp-65(gene name)|psi-mi:msp-65(display_short)|uniprotkb:ZK354.1(orf name)|uniprotkb:msp-81(gene name)|psi-mi:msp-81(display_short)|uniprotkb:K07F5.1(orf name)|uniprotkb:msp-113(gene name)|psi-mi:msp-113(display_short)|uniprotkb:ZK354.4(orf name)|uniprotkb:msp-142(gene name)|psi-mi:msp-142(display_short)|uniprotkb:K05F1.2(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545402|imex:IM-18681-970 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494865.1|refseq:NP_494898.1|refseq:NP_494959.1|refseq:NP_494972.1|refseq:NP_495144.1|refseq:NP_495149.1|refseq:NP_500714.1|refseq:NP_500760.1|refseq:NP_500771.1|refseq:NP_500773.1|refseq:NP_500778.1|refseq:NP_500780.1|refseq:NP_501759.1|wormbase:C33F10.9|wormbase:C34F11.4|ensemblmetazoa:ZK1248.6.1(transcript)|ensemblmetazoa:ZK354.1.1(transcript)|ensemblmetazoa:ZK354.11.1(transcript)|ensemblmetazoa:ZK354.4.1(transcript)|ensemblmetazoa:ZK354.5.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0031143"(pseudopodium)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:1GRW|wormbase:F36H12.7|wormbase:F58A6.8|wormbase:K05F1.2|wormbase:K07F5.1|wormbase:R05F9.13|wormbase:R13H9.4|wormbase:ZK1248.6|wormbase:ZK354.1|wormbase:ZK354.11|wormbase:ZK354.4|wormbase:ZK354.5|ensemblmetazoa:K05F1.2.1(transcript)|ensemblmetazoa:R05F9.13.1(transcript)|ensemblmetazoa:R13H9.4.1(transcript)|ensemblmetazoa:WBGene00003426(gene)|ensemblmetazoa:WBGene00003429(gene)|ensemblmetazoa:WBGene00003435(gene)|ensemblmetazoa:WBGene00003438(gene)|ensemblmetazoa:WBGene00003443(gene)|ensemblmetazoa:WBGene00003444(gene)|ensemblmetazoa:WBGene00003446(gene)|ensemblmetazoa:WBGene00003452(gene)|ensemblmetazoa:C33F10.9.1(transcript)|ensemblmetazoa:WBGene00003457(gene)|ensemblmetazoa:C34F11.4.1(transcript)|ensemblmetazoa:WBGene00003458(gene)|ensemblmetazoa:WBGene00003468(gene)|ensemblmetazoa:WBGene00003469(gene)|ensemblmetazoa:F36H12.7.1(transcript)|ensemblmetazoa:F58A6.8.1(transcript)|dip:DIP-25397N|uniprotkb:P53017(identity)|wormbase:WBGene00003435(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lyj6lPHOYPArvIgkGyARLhGftCA6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:7C7C12CDB13C2767|rigid:J/fblHM1VDLDPYQ022yT+YW8iLE false - sufficient binding region:897-951 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A7LPD5 uniprotkb:Q9U2T9 intact:EBI-6545417|ensemblmetazoa:F59G1.8a.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:a7lpd5_caeel(display_long)|uniprotkb:CELE_F59G1.8(orf name)|uniprotkb:F59G1.8(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545419|imex:IM-18681-971 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F59G1.8a.1(transcript)|ensemblmetazoa:WBGene00019129(gene)|refseq:NP_001122617.2|wormbase:F59G1.8a|uniprotkb:A7LPD5(identity)|wormbase:WBGene00019129(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KjiyqMjIt+z0Y+vasPUhMN+V2Ac6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:6DE1F77FC6CD91F8|rigid:sditdj0PGpSnlHHKHr3zcGtwaq8 false - sufficient binding region:897-951 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P53017 uniprotkb:Q9U2T9 intact:EBI-319681|ensemblmetazoa:ZK354.1.1|ensemblmetazoa:ZK354.11.1|ensemblmetazoa:ZK354.4.1|ensemblmetazoa:ZK354.5.1|ensemblmetazoa:K05F1.2.1|ensemblmetazoa:R05F9.13.1|ensemblmetazoa:R13H9.4.1|ensemblmetazoa:C33F10.9.1|ensemblmetazoa:C34F11.4.1|ensemblmetazoa:F36H12.7.1|ensemblmetazoa:ZK1248.6.1|ensemblmetazoa:F58A6.8.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:msp19_caeel(display_long)|uniprotkb:msp-19(gene name)|psi-mi:msp-19(display_short)|uniprotkb:F36H12.7(orf name)|uniprotkb:msp-31(gene name)|psi-mi:msp-31(display_short)|uniprotkb:R05F9.13(orf name)|uniprotkb:msp-40(gene name)|psi-mi:msp-40(display_short)|uniprotkb:C33F10.9(orf name)|uniprotkb:msp-45(gene name)|psi-mi:msp-45(display_short)|uniprotkb:F58A6.8(orf name)|uniprotkb:msp-50(gene name)|psi-mi:msp-50(display_short)|uniprotkb:C34F11.4(orf name)|uniprotkb:msp-51(gene name)|psi-mi:msp-51(display_short)|uniprotkb:ZK354.5(orf name)|uniprotkb:msp-53(gene name)|psi-mi:msp-53(display_short)|uniprotkb:R13H9.4(orf name)|uniprotkb:msp-59(gene name)|psi-mi:msp-59(display_short)|uniprotkb:ZK354.11(orf name)|uniprotkb:msp-64(gene name)|psi-mi:msp-64(display_short)|uniprotkb:ZK1248.6(orf name)|uniprotkb:msp-65(gene name)|psi-mi:msp-65(display_short)|uniprotkb:ZK354.1(orf name)|uniprotkb:msp-81(gene name)|psi-mi:msp-81(display_short)|uniprotkb:K07F5.1(orf name)|uniprotkb:msp-113(gene name)|psi-mi:msp-113(display_short)|uniprotkb:ZK354.4(orf name)|uniprotkb:msp-142(gene name)|psi-mi:msp-142(display_short)|uniprotkb:K05F1.2(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545434|imex:IM-18681-972 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494865.1|refseq:NP_494898.1|refseq:NP_494959.1|refseq:NP_494972.1|refseq:NP_495144.1|refseq:NP_495149.1|refseq:NP_500714.1|refseq:NP_500760.1|refseq:NP_500771.1|refseq:NP_500773.1|refseq:NP_500778.1|refseq:NP_500780.1|refseq:NP_501759.1|wormbase:C33F10.9|wormbase:C34F11.4|ensemblmetazoa:ZK1248.6.1(transcript)|ensemblmetazoa:ZK354.1.1(transcript)|ensemblmetazoa:ZK354.11.1(transcript)|ensemblmetazoa:ZK354.4.1(transcript)|ensemblmetazoa:ZK354.5.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0031143"(pseudopodium)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:1GRW|wormbase:F36H12.7|wormbase:F58A6.8|wormbase:K05F1.2|wormbase:K07F5.1|wormbase:R05F9.13|wormbase:R13H9.4|wormbase:ZK1248.6|wormbase:ZK354.1|wormbase:ZK354.11|wormbase:ZK354.4|wormbase:ZK354.5|ensemblmetazoa:K05F1.2.1(transcript)|ensemblmetazoa:R05F9.13.1(transcript)|ensemblmetazoa:R13H9.4.1(transcript)|ensemblmetazoa:WBGene00003426(gene)|ensemblmetazoa:WBGene00003429(gene)|ensemblmetazoa:WBGene00003435(gene)|ensemblmetazoa:WBGene00003438(gene)|ensemblmetazoa:WBGene00003443(gene)|ensemblmetazoa:WBGene00003444(gene)|ensemblmetazoa:WBGene00003446(gene)|ensemblmetazoa:WBGene00003452(gene)|ensemblmetazoa:C33F10.9.1(transcript)|ensemblmetazoa:WBGene00003457(gene)|ensemblmetazoa:C34F11.4.1(transcript)|ensemblmetazoa:WBGene00003458(gene)|ensemblmetazoa:WBGene00003468(gene)|ensemblmetazoa:WBGene00003469(gene)|ensemblmetazoa:F36H12.7.1(transcript)|ensemblmetazoa:F58A6.8.1(transcript)|dip:DIP-25397N|uniprotkb:P53017(identity)|wormbase:WBGene00003467(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 16|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lyj6lPHOYPArvIgkGyARLhGftCA6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:DB2A867BFD8BFC1F|rigid:J/fblHM1VDLDPYQ022yT+YW8iLE false - sufficient binding region:897-951 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P05634 uniprotkb:Q9U2T9 intact:EBI-6545449|ensemblmetazoa:C04G2.4.1|ensemblmetazoa:K07F5.2.1|ensemblmetazoa:K07F5.3.1|ensemblmetazoa:ZK1251.6.1|uniprotkb:P05635|uniprotkb:Q27280 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:msp10_caeel(display_long)|uniprotkb:msp-10(gene name)|psi-mi:msp-10(display_short)|uniprotkb:msp-36(gene name)|psi-mi:msp-36(display_short)|uniprotkb:msp-56(gene name)|psi-mi:msp-56(display_short)|uniprotkb:msp-76(gene name)|psi-mi:msp-76(display_short)|uniprotkb:C04G2.4(orf name)|uniprotkb:K07F5.2(orf name)|uniprotkb:K07F5.3(orf name)|uniprotkb:ZK1251.6(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545451|imex:IM-18681-973 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|refseq:NP_501722.1|refseq:NP_501760.1|refseq:NP_501762.1|refseq:NP_501834.1|wormbase:C04G2.4|wormbase:K07F5.2|wormbase:K07F5.3|ensemblmetazoa:C04G2.4.1(transcript)|ensemblmetazoa:K07F5.2.1(transcript)|ensemblmetazoa:K07F5.3.1(transcript)|ensemblmetazoa:WBGene00003425(gene)|ensemblmetazoa:WBGene00003432(gene)|ensemblmetazoa:WBGene00003449(gene)|ensemblmetazoa:WBGene00003463(gene)|ensemblmetazoa:ZK1251.6.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0031143"(pseudopodium)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:ZK1251.6|uniprotkb:P05634(identity)|wormbase:WBGene00003449(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:jjsLq+pioAZakxRvAuB3M+mz7Kc6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:BCB2527F90D2367F|rigid:9uxINub3RQoccOUxZizKpWlcNCo false - sufficient binding region:897-951 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N2Z7 uniprotkb:Q9U2T9 intact:EBI-317369|uniprotkb:Q95XU3|uniprotkb:V6CJJ8|uniprotkb:V6CLY4|ensemblmetazoa:Y65B4BR.4a.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:wwp1_caeel(display_long)|uniprotkb:wwp-1(gene name)|psi-mi:wwp-1(display_short)|uniprotkb:Y65B4BR.4(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545466|imex:IM-18681-974 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y65B4BR.4b|wormbase:Y65B4BR.4c|wormbase:Y65B4BR.4d|refseq:NP_740775.1|wormbase:Y65B4BR.4a|ensemblmetazoa:WBGene00007009(gene)|ensemblmetazoa:Y65B4BR.4a.1(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|reactome:R-CEL-1253288|reactome:R-CEL-983168|reactome:R-CEL-9013406|reactome:R-CEL-9013420|refseq:NP_001293271.1|refseq:NP_001293272.1|refseq:NP_740776.1|dip:DIP-25758N|reactome:R-CEL-2672351|reactome:R-CEL-8948751|reactome:R-CEL-5610780|reactome:R-CEL-5632684|uniprotkb:Q95XU3(identity)|wormbase:WBGene00007009(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2021/06/18 rogid:PlZNO3kcb422riUzp2aLH7Xaz3E6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:678918CD31C6EB1D|rigid:h4dIORzie/gRmADRBIMBtexaauw false - sufficient binding region:897-951 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10457 uniprotkb:Q9U2T9 intact:EBI-311886|ensemblmetazoa:B0286.3.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545481|imex:IM-18681-975 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:1DE93D045FE1D5A3|rigid:6Arjc2qBqeDsPNG4Pv75cuhg/2w false - sufficient binding region:974-1033 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2T9 uniprotkb:Q9XTY6 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 intact:EBI-495781|uniprotkb:Q9BKB5|uniprotkb:Q9XTY4|ensemblmetazoa:T03D8.1a.1 psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:numb1_caeel(display_long)|uniprotkb:Protein kinase C adapter 1(gene name synonym)|uniprotkb:CKA1(gene name synonym)|uniprotkb:num-1(gene name)|psi-mi:num-1(display_short)|uniprotkb:cka-1(gene name synonym)|uniprotkb:T03D8.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545496|imex:IM-18681-976 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) refseq:NP_001024097.1|refseq:NP_001024098.1|refseq:NP_508021.1|wormbase:T03D8.1a|wormbase:T03D8.1b|wormbase:T03D8.1c|interpro:IPR016698(Numb/numb-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|reactome:R-CEL-437239|reactome:R-CEL-5610780|reactome:R-CEL-5632684|ensemblmetazoa:T03D8.1a.1(transcript)|ensemblmetazoa:WBGene00003830(gene)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0051117"(ATPase binding)|uniprotkb:Q9XTY6(identity)|wormbase:WBGene00003830(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 90|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 rogid:qO+DFvMBt2DE+ZS7l8axk5DMOFQ6239 intact-crc:5624790743ADB23A|rigid:n/cdSAKvhrrEcwawI0/J07caUBM false sufficient binding region:974-1033 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10457 uniprotkb:Q9U2T9 intact:EBI-311886|ensemblmetazoa:B0286.3.1 intact:EBI-2414252|ensemblmetazoa:Y116A8C.36a.1 psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:q9u2t9_caeel(display_long)|uniprotkb:itsn-1(gene name)|psi-mi:itsn-1(display_short)|uniprotkb:CELE_Y116A8C.36(orf name)|uniprotkb:Y116A8C.36(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545511|imex:IM-18681-977 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) wormbase:Y116A8C.36a|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001452(Src homology-3)|refseq:NP_001255927.1|ensemblmetazoa:WBGene00006405(gene)|ensemblmetazoa:Y116A8C.36a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR036028|uniprotkb:E6N0W0(identity)|wormbase:WBGene00006405(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 rogid:ogVK0k9DQi34lhLycZR+S5YjfaI6239 intact-crc:482FFC99022E2B52|rigid:6Arjc2qBqeDsPNG4Pv75cuhg/2w false - sufficient binding region:1040-1085 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XA9 uniprotkb:Q11181 intact:EBI-6537613|ensemblmetazoa:Y20F4.3a.1|uniprotkb:G4SRM7 intact:EBI-2316016|uniprotkb:Q8T3F3|uniprotkb:Q8T3F4|uniprotkb:Q8T3F5|ensemblmetazoa:C05D10.4b.1 psi-mi:q95xa9_caeel(display_long)|uniprotkb:Y20F4.3(orf name)|uniprotkb:gap-3(gene name)|psi-mi:gap-3(display_short)|uniprotkb:CELE_Y20F4.3(orf name) psi-mi:ypc4_caeel(display_long)|uniprotkb:C05D10.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545526|imex:IM-18681-978 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021238(gene)|ensemblmetazoa:Y20F4.3a.1(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0043409"(negative regulation of MAPK cascade)|wormbase:Y20F4.3a|reactome:R-CEL-186763|reactome:R-CEL-8849471|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|refseq:NP_490916.5|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95XA9(identity)|wormbase:WBGene00021238(identity) refseq:NP_498323.2|refseq:NP_498324.2|refseq:NP_741170.1|wormbase:C05D10.4a|wormbase:C05D10.4b|wormbase:C05D10.4c|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|ensemblmetazoa:C05D10.4b.1(transcript)|ensemblmetazoa:WBGene00015480(gene)|uniprotkb:Q11181(identity)|wormbase:WBGene00015480(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W7Klw/TiaXQdDxym/p8FIth/Gn46239 rogid:msS16ZOpmue9+9+to7VFLPE1TM86239 intact-crc:829510D9576B4259|rigid:+P5KrByPxNmA1mMd3AK7O9Mwulw false sufficient binding region:211-268 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XA9 uniprotkb:Q19781 intact:EBI-6537613|ensemblmetazoa:Y20F4.3a.1|uniprotkb:G4SRM7 intact:EBI-2416575|ensemblmetazoa:F25E2.3.1 psi-mi:q95xa9_caeel(display_long)|uniprotkb:Y20F4.3(orf name)|uniprotkb:gap-3(gene name)|psi-mi:gap-3(display_short)|uniprotkb:CELE_Y20F4.3(orf name) psi-mi:q19781_caeel(display_long)|uniprotkb:F25E2.3(orf name)|uniprotkb:CELE_F25E2.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545541|imex:IM-18681-979 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021238(gene)|ensemblmetazoa:Y20F4.3a.1(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0043409"(negative regulation of MAPK cascade)|wormbase:Y20F4.3a|reactome:R-CEL-186763|reactome:R-CEL-8849471|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|refseq:NP_490916.5|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95XA9(identity)|wormbase:WBGene00021238(identity) refseq:NP_508159.2|wormbase:F25E2.3|interpro:IPR003703(Acyl-CoA thioesterase)|interpro:IPR029069|interpro:IPR042171|ensemblmetazoa:F25E2.3.1(transcript)|ensemblmetazoa:WBGene00017781(gene)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0047617"(acyl-CoA hydrolase activity)|uniprotkb:Q19781(identity)|wormbase:WBGene00017781(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 18|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W7Klw/TiaXQdDxym/p8FIth/Gn46239 rogid:9N2uEVBSUcKHyOJkL+oFtu8qCbw6239 intact-crc:1C545160B0EBC74B|rigid:io1PHhlRfoZfZFzDX4e3CuStDJM false sufficient binding region:211-268 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XA9 uniprotkb:Q19980 intact:EBI-6537613|ensemblmetazoa:Y20F4.3a.1|uniprotkb:G4SRM7 intact:EBI-311852|intact:EBI-2923863|ensemblmetazoa:F32G8.6.1 psi-mi:q95xa9_caeel(display_long)|uniprotkb:Y20F4.3(orf name)|uniprotkb:gap-3(gene name)|psi-mi:gap-3(display_short)|uniprotkb:CELE_Y20F4.3(orf name) psi-mi:gch1_caeel(display_long)|uniprotkb:F32G8.6(orf name)|uniprotkb:cat-4(gene name)|psi-mi:cat-4(display_short)|uniprotkb:GTP cyclohydrolase I(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545556|imex:IM-18681-980 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021238(gene)|ensemblmetazoa:Y20F4.3a.1(transcript)|go:"GO:0007165"(signal transduction)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008306"(associative learning)|go:"GO:0043409"(negative regulation of MAPK cascade)|wormbase:Y20F4.3a|reactome:R-CEL-186763|reactome:R-CEL-8849471|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-912631|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|refseq:NP_490916.5|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95XA9(identity)|wormbase:WBGene00021238(identity) reactome:R-CEL-1474151|ensemblmetazoa:F32G8.6.1(transcript)|ensemblmetazoa:WBGene00000298(gene)|go:"GO:0003934"(GTP cyclohydrolase I activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006585"(dopamine biosynthetic process from tyrosine)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035998"(7,8-dihydroneopterin 3'-triphosphate biosynthetic process)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|interpro:IPR001474(GTP cyclohydrolase I)|interpro:IPR018234|interpro:IPR020602|interpro:IPR043133|interpro:IPR043134|refseq:NP_505710.1|wormbase:F32G8.6|dip:DIP-24416N|uniprotkb:Q19980(identity)|wormbase:WBGene00000298(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 21|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W7Klw/TiaXQdDxym/p8FIth/Gn46239 rogid:U2OFSeuyYv3PuNaKvKKf0CA9KO06239 intact-crc:3C6AC6B1899F738A|rigid:TFc78A3KI2Grxvl9UBTrDL6ZG40 false sufficient binding region:211-268 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P22980 uniprotkb:G5ECK4 intact:EBI-2408789|ensemblmetazoa:B0304.1b.1|ensemblmetazoa:B0304.1b.2 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:myod1_caeel(display_long)|uniprotkb:hlh-1(gene name)|psi-mi:hlh-1(display_short)|uniprotkb:Helix-loop-helix protein 1(gene name synonym)|uniprotkb:B0304.1(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545571|imex:IM-18681-981 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039704|refseq:NP_001021892.1|refseq:NP_001021893.1|refseq:NP_494798.4|wormbase:B0304.1a|wormbase:B0304.1b|wormbase:B0304.1c|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:B0304.1b.1(transcript)|ensemblmetazoa:B0304.1b.2(transcript)|ensemblmetazoa:WBGene00001948(gene)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|uniprotkb:P22980(identity)|wormbase:WBGene00001948(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eywXRvNPsdS4BZHvdENEN20kEWg6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:EFFD782EE546191F|rigid:kdqDtb9tC8O7g8sgDxxgURCJkFA false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91001 uniprotkb:G5ECK4 intact:EBI-313007|ensemblmetazoa:B0547.1.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545586|imex:IM-18681-982 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394|uniprotkb:P91001(identity)|wormbase:WBGene00000817(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:ACF6830CBE6E1AF6|rigid:pkYDcXm1p0pDHO7Qzi/APJ5c1yQ false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39055 uniprotkb:G5ECK4 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545601|imex:IM-18681-983 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 42|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:623BF78CB668D4AF|rigid:1osvjpZSpAVuMsvcfbirh6m9Trk false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q11181 uniprotkb:G5ECK4 intact:EBI-2316016|uniprotkb:Q8T3F3|uniprotkb:Q8T3F4|uniprotkb:Q8T3F5|ensemblmetazoa:C05D10.4b.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:ypc4_caeel(display_long)|uniprotkb:C05D10.4(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545616|imex:IM-18681-984 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498323.2|refseq:NP_498324.2|refseq:NP_741170.1|wormbase:C05D10.4a|wormbase:C05D10.4b|wormbase:C05D10.4c|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|ensemblmetazoa:C05D10.4b.1(transcript)|ensemblmetazoa:WBGene00015480(gene)|uniprotkb:Q11181(identity)|wormbase:WBGene00015480(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:msS16ZOpmue9+9+to7VFLPE1TM86239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:887058C435F95E0F|rigid:qu7q2+nL7w4C3t5sM2HtVr5cX4s false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:O45134 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-324693|ensemblmetazoa:C05D2.5.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:o45134_caeel(display_long)|uniprotkb:xnd-1(gene name)|psi-mi:xnd-1(display_short)|uniprotkb:C05D2.5(orf name)|uniprotkb:CELE_C05D2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545631|imex:IM-18681-985 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_498207.1|wormbase:C05D2.5|ensemblmetazoa:C05D2.5.1(transcript)|ensemblmetazoa:WBGene00001514(gene)|dip:DIP-24820N|uniprotkb:O45134(identity)|wormbase:WBGene00001514(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:lHZ09WJWDID3h3TwsWRPCx7SnBM6239 intact-crc:BA1D23D8F0548DEE|rigid:P0H7Sq6r6CCS8L2R+nuEi/9sdQo false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17865 uniprotkb:G5ECK4 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545646|imex:IM-18681-986 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:BC635F19B8402AD8|rigid:TYWkAOA8tKRBRyKeW9hEK9G6mwg false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q95QQ9 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-2317344|ensemblmetazoa:C49H3.6a.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q95qq9_caeel(display_long)|uniprotkb:C49H3.6(orf name)|uniprotkb:CELE_C49H3.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545661|imex:IM-18681-987 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_501316.2|wormbase:C49H3.6a|interpro:IPR019131|ensemblmetazoa:C49H3.6a.1(transcript)|ensemblmetazoa:WBGene00016792(gene)|go:"GO:0005737"(cytoplasm)|uniprotkb:Q95QQ9(identity)|wormbase:WBGene00016792(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:eHT6KUXkocreuSpbjuHpYT+s+tQ6239 intact-crc:4A49181DB4E2C2B0|rigid:KtcWa9FaFPH7xawipvR1btoRpSQ false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:C1P629 uniprotkb:G5ECK4 intact:EBI-6543282|ensemblmetazoa:D1046.1b.1|ensemblmetazoa:D1046.1b.2|ensemblmetazoa:D1046.1b.3 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:c1p629_caeel(display_long)|uniprotkb:D1046.1(orf name)|uniprotkb:cfim-2(gene name)|psi-mi:cfim-2(display_short)|uniprotkb:CELE_D1046.1(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545676|imex:IM-18681-988 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:D1046.1b.1(transcript)|ensemblmetazoa:D1046.1b.2(transcript)|ensemblmetazoa:D1046.1b.3(transcript)|ensemblmetazoa:WBGene00008362(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|refseq:NP_001255353.1|wormbase:D1046.1b|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|interpro:IPR034771|interpro:IPR034772|interpro:IPR035979|reactome:R-CEL-73856|uniprotkb:C1P629(identity)|wormbase:WBGene00008362(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:+JtJiDoORwTvoibcdzaybyeZJmw6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:ECA83AB84117E702|rigid:+R6P5QM6jy/GTv+lBOyPLM+jiGc false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17777 uniprotkb:G5ECK4 intact:EBI-319330|ensemblmetazoa:F10D11.2.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:o17777_caeel(display_long)|uniprotkb:F10D11.2(orf name)|uniprotkb:CELE_F10D11.2(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545691|imex:IM-18681-989 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492291.2|wormbase:F10D11.2|ensemblmetazoa:F10D11.2.1(transcript)|ensemblmetazoa:WBGene00008648(gene)|uniprotkb:O17777(identity)|wormbase:WBGene00008648(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:itdYwiEPBfp46ka/nwcIHdZTZto6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:B69D311C3A59663E|rigid:ndO2O032HWvL0pADCUxuTXH4aUQ false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19416 uniprotkb:G5ECK4 intact:EBI-319517|ensemblmetazoa:F13G3.4.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:q19416_caeel(display_long)|uniprotkb:dylt-1(gene name)|psi-mi:dylt-1(display_short)|uniprotkb:F13G3.4(orf name)|uniprotkb:CELE_F13G3.4(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545706|imex:IM-18681-990 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492063.1|wormbase:F13G3.4|ensemblmetazoa:F13G3.4.1(transcript)|ensemblmetazoa:WBGene00008764(gene)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|dip:DIP-26956N|reactome:R-CEL-6798695|uniprotkb:Q19416(identity)|wormbase:WBGene00008764(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:UL1DI9ebFykwO7Hk7QgxC886Zz46239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:7152CE4FF2F03CB2|rigid:X5M9xyKeveCoS2t8/su8NoyXttY false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q8MNT0 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-324442|ensemblmetazoa:F28F5.3c.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q8mnt0_caeel(display_long)|uniprotkb:lim-8(gene name)|psi-mi:lim-8(display_short)|uniprotkb:F28F5.3(orf name)|uniprotkb:CELE_F28F5.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545721|imex:IM-18681-991 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_741201.1|wormbase:F28F5.3c|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|ensemblmetazoa:F28F5.3c.1(transcript)|ensemblmetazoa:WBGene00017904(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031430"(M band)|go:"GO:0032034"(myosin II head/neck binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|interpro:IPR036034|interpro:IPR041489|interpro:IPR029980|uniprotkb:Q8MNT0(identity)|wormbase:WBGene00017904(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:Prm6YPAZkkBApz/l8EwwI2JDZvk6239 intact-crc:483D4BE50CE61CAA|rigid:8c+7B6aoobNi0aNtHG8HKm0Lm0A false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19994 uniprotkb:G5ECK4 intact:EBI-2316468|ensemblmetazoa:F34D10.4.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:q19994_caeel(display_long)|uniprotkb:F34D10.4(orf name)|uniprotkb:CELE_F34D10.4(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545736|imex:IM-18681-992 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497758.1|wormbase:F34D10.4|ensemblmetazoa:F34D10.4.1(transcript)|ensemblmetazoa:WBGene00009374(gene)|uniprotkb:Q19994(identity)|wormbase:WBGene00009374(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Yyp9k3/LEbiLhySq1vul5tfQN6o6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:F41A74CA70E7BDB0|rigid:w3OfBABEi74/shgST7i0fJyLNsE false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q9U2D6 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-329790|ensemblmetazoa:Y46G5A.10.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:cnp2_caeel(display_long)|uniprotkb:cnp-2(gene name)|psi-mi:cnp-2(display_short)|uniprotkb:Calcineurin binding protein 2(gene name synonym)|uniprotkb:Y46G5A.10(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545751|imex:IM-18681-993 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_496715.3|wormbase:Y46G5A.10|dip:DIP-26531N|ensemblmetazoa:WBGene00012901(gene)|ensemblmetazoa:Y46G5A.10.1(transcript)|reactome:R-CEL-5621480|reactome:R-CEL-913709|uniprotkb:Q9U2D6(identity)|wormbase:WBGene00012901(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:c283678sLaAPqMx0BPNxcEYLzhE6239 intact-crc:FACE6C90E077A332|rigid:DCUUBSOXtH3P8gZBeHDCTjB9NzA false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECG0 uniprotkb:G5ECK4 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545766|imex:IM-18681-994 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3|uniprotkb:G5ECG0(identity)|wormbase:WBGene00006381(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:02FA2357A64EE31C|rigid:iQm/R125nP9/g9Ugxzv7lMXQcPY false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q4VNJ8 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-2918529 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545781|imex:IM-18681-995 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 intact-crc:C25C9C533AB0FD31|rigid:yu/KpmobzXUAKwnCTrGyX6InRC8 false sufficient binding region:171-227 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GYG1 uniprotkb:G5ECK4 intact:EBI-314846|ensemblmetazoa:ZC395.8.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:q9gyg1_caeel(display_long)|uniprotkb:ztf-8(gene name)|psi-mi:ztf-8(display_short)|uniprotkb:CELE_ZC395.8(orf name)|uniprotkb:ZC395.8(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545796|imex:IM-18681-996 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498124.2|wormbase:ZC395.8|ensemblmetazoa:WBGene00022598(gene)|ensemblmetazoa:ZC395.8.1(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|dip:DIP-24679N|uniprotkb:Q9GYG1(identity)|wormbase:WBGene00022598(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:wsZC5q+nCfg+Qz99e0wmwQZxK4A6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:EF05FFF8B8F0BD35|rigid:PzEbGsFMzvHkHxHz/MNjKgab0QQ false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BIF4 uniprotkb:G5ECK4 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545811|imex:IM-18681-997 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/09 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:B9CE28420B90827B|rigid:pntVx2FGbStIbHYSZOASINfLo+g false - sufficient binding region:171-227 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8I4E2 uniprotkb:P39055 intact:EBI-4325777|uniprotkb:D3NQ98|uniprotkb:J7SA60|uniprotkb:Q8I4E1|uniprotkb:Q9XXG2|uniprotkb:Q9XXG3|ensemblmetazoa:Y37A1B.2c.1 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:lst4_caeel(display_long)|uniprotkb:lst-4(gene name)|psi-mi:lst-4(display_short)|uniprotkb:Lateral signaling target protein 4(gene name synonym)|uniprotkb:Y37A1B.2(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545826|imex:IM-18681-998 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036871|interpro:IPR027267|interpro:IPR036028|wormbase:Y37A1B.2d|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|reactome:R-CEL-8856828|refseq:NP_502693.2|wormbase:Y37A1B.2a|wormbase:Y37A1B.2b|wormbase:Y37A1B.2c|wormbase:Y37A1B.2e|wormbase:Y37A1B.2f|refseq:NP_001255779.1|refseq:NP_001263811.1|refseq:NP_502694.1|refseq:NP_502695.2|refseq:NP_872090.1|reactome:R-CEL-432722|go:"GO:0032009"(early phagosome)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045335"(phagocytic vesicle)|ensemblmetazoa:WBGene00003086(gene)|ensemblmetazoa:Y37A1B.2c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0090389"(phagosome-lysosome fusion involved in apoptotic cell clearance)|go:"GO:0097194"(execution phase of apoptosis) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:NqGhrxQdIIT2DDOgu+/swsZFniQ6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:93C08800052E2B33|rigid:BznmhiVYxKJWY3voUGDupXIylo4 false sufficient binding region:2-60 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8I4E2 uniprotkb:Q17795 intact:EBI-4325777|uniprotkb:D3NQ98|uniprotkb:J7SA60|uniprotkb:Q8I4E1|uniprotkb:Q9XXG2|uniprotkb:Q9XXG3|ensemblmetazoa:Y37A1B.2c.1 intact:EBI-2316131|ensemblmetazoa:C07G1.4a.1 psi-mi:lst4_caeel(display_long)|uniprotkb:lst-4(gene name)|psi-mi:lst-4(display_short)|uniprotkb:Lateral signaling target protein 4(gene name synonym)|uniprotkb:Y37A1B.2(orf name) psi-mi:q17795_caeel(display_long)|uniprotkb:wsp-1(gene name)|psi-mi:wsp-1(display_short)|uniprotkb:CELE_C07G1.4(orf name)|uniprotkb:C07G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545841|imex:IM-18681-999 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036871|interpro:IPR027267|interpro:IPR036028|wormbase:Y37A1B.2d|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|reactome:R-CEL-8856828|refseq:NP_502693.2|wormbase:Y37A1B.2a|wormbase:Y37A1B.2b|wormbase:Y37A1B.2c|wormbase:Y37A1B.2e|wormbase:Y37A1B.2f|refseq:NP_001255779.1|refseq:NP_001263811.1|refseq:NP_502694.1|refseq:NP_502695.2|refseq:NP_872090.1|reactome:R-CEL-432722|go:"GO:0032009"(early phagosome)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045335"(phagocytic vesicle)|ensemblmetazoa:WBGene00003086(gene)|ensemblmetazoa:Y37A1B.2c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0090389"(phagosome-lysosome fusion involved in apoptotic cell clearance)|go:"GO:0097194"(execution phase of apoptosis) refseq:NP_741459.2|wormbase:C07G1.4a|interpro:IPR000697(EVH1)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR033927|interpro:IPR036936|interpro:IPR030214|ensemblmetazoa:C07G1.4a.1(transcript)|ensemblmetazoa:WBGene00006957(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|uniprotkb:Q17795(identity)|wormbase:WBGene00006957(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:NqGhrxQdIIT2DDOgu+/swsZFniQ6239 rogid:YBTDOwM+8a5vUAiihYM6ezASlGY6239 intact-crc:BB18AAE3AC1C59C0|rigid:TWcfTX1lFgGhhS4Jg7zvlkQjXeI false sufficient binding region:2-60 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8I4E2 uniprotkb:O16299 intact:EBI-4325777|uniprotkb:D3NQ98|uniprotkb:J7SA60|uniprotkb:Q8I4E1|uniprotkb:Q9XXG2|uniprotkb:Q9XXG3|ensemblmetazoa:Y37A1B.2c.1 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 psi-mi:lst4_caeel(display_long)|uniprotkb:lst-4(gene name)|psi-mi:lst-4(display_short)|uniprotkb:Lateral signaling target protein 4(gene name synonym)|uniprotkb:Y37A1B.2(orf name) psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545856|imex:IM-18681-1000 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036871|interpro:IPR027267|interpro:IPR036028|wormbase:Y37A1B.2d|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|reactome:R-CEL-8856828|refseq:NP_502693.2|wormbase:Y37A1B.2a|wormbase:Y37A1B.2b|wormbase:Y37A1B.2c|wormbase:Y37A1B.2e|wormbase:Y37A1B.2f|refseq:NP_001255779.1|refseq:NP_001263811.1|refseq:NP_502694.1|refseq:NP_502695.2|refseq:NP_872090.1|reactome:R-CEL-432722|go:"GO:0032009"(early phagosome)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045335"(phagocytic vesicle)|ensemblmetazoa:WBGene00003086(gene)|ensemblmetazoa:Y37A1B.2c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0090389"(phagosome-lysosome fusion involved in apoptotic cell clearance)|go:"GO:0097194"(execution phase of apoptosis) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 118|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:NqGhrxQdIIT2DDOgu+/swsZFniQ6239 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 intact-crc:2E4FCF3F2B48C79D|rigid:jmrhIUnEZftAg0ZoC2Sd6c2kvzc false sufficient binding region:2-60 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:Q10457 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-311886|ensemblmetazoa:B0286.3.1 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545871|imex:IM-18681-1001 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 intact-crc:A7D7585426993B6B|rigid:qsunBWXfqIsgB2+XzSSySE+FHcI false sufficient binding region:62-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17865 uniprotkb:Q9N415 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545886|imex:IM-18681-1002 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 37|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 intact-crc:3279A8494F71083E|rigid:RtBZNYhi8VdEOFqt3HRiwEGT0U0 false - sufficient binding region:62-126 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QQ9 uniprotkb:Q9N415 intact:EBI-2317344|ensemblmetazoa:C49H3.6a.1 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 psi-mi:q95qq9_caeel(display_long)|uniprotkb:C49H3.6(orf name)|uniprotkb:CELE_C49H3.6(orf name) psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545901|imex:IM-18681-1003 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501316.2|wormbase:C49H3.6a|interpro:IPR019131|ensemblmetazoa:C49H3.6a.1(transcript)|ensemblmetazoa:WBGene00016792(gene)|go:"GO:0005737"(cytoplasm)|uniprotkb:Q95QQ9(identity)|wormbase:WBGene00016792(identity) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:eHT6KUXkocreuSpbjuHpYT+s+tQ6239 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 intact-crc:71D20403D19206FE|rigid:nJtSzcOfZWEiNMopyWCog984FM4 false - sufficient binding region:62-126 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:Q19807 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-6545920|ensemblmetazoa:F26A10.2.1 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:q19807_caeel(display_long)|uniprotkb:CELE_F26A10.2(orf name)|uniprotkb:F26A10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545916|imex:IM-18681-1004 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) ensemblmetazoa:F26A10.2.1(transcript)|ensemblmetazoa:WBGene00017814(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_509290.1|wormbase:F26A10.2|interpro:IPR036236|uniprotkb:Q19807(identity)|wormbase:WBGene00017814(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:Vi7YXMuDEQncAwD8CWrhv5HHzN86239 intact-crc:767F17F540FFFB13|rigid:l4Xa9YasWy0G90KogieQv75vsKE false sufficient binding region:62-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:G5EDZ2 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-313698|ensemblmetazoa:T07C4.1.1|ensemblmetazoa:T07C4.1.2 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:umps_caeel(display_long)|uniprotkb:umps-1(gene name)|psi-mi:umps-1(display_short)|uniprotkb:rad-6(gene name synonym)|uniprotkb:T07C4.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545933|imex:IM-18681-1005 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) uniprotkb:Q18516(uniprot-removed-ac)|interpro:IPR001754(Orotidine 5'-phosphate decarboxylase, core)|interpro:IPR004467(Orotate phosphoribosyl transferase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR014732(Orotidine 5'-phosphate decarboxylase, subfamily 1, core)|interpro:IPR023031|refseq:NP_499291.1|mint:G5EDZ2|wormbase:T07C4.1|ensemblmetazoa:T07C4.1.1(transcript)|ensemblmetazoa:T07C4.1.2(transcript)|ensemblmetazoa:WBGene00011559(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0004588"(orotate phosphoribosyltransferase activity)|go:"GO:0004590"(orotidine-5'-phosphate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006222"(UMP biosynthetic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009411"(response to UV)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0090727"(positive regulation of brood size)|reactome:R-CEL-500753|interpro:IPR029057|interpro:IPR000836(Phosphoribosyltransferase)|uniprotkb:G5EDZ2(identity)|wormbase:WBGene00011559(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:Cpk0wa1uimBSN+c829/7jJMJdLk6239 intact-crc:2BAC4E1F046053E5|rigid:20gxg/ukHdZ6ql98ukmMJdu53CA false sufficient binding region:62-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:A5HBK2 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-2916077 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:a5hbk2_caeel(display_long)|uniprotkb:SCRM-1(gene name)|psi-mi:SCRM-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545948|imex:IM-18681-1006 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) go:"GO:0017128"(phospholipid scramblase activity)|interpro:IPR005552(Scramblase)|interpro:IPR025659|uniprotkb:A5HBK2(identity)|wormbase:WBGene00011935(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:S3FBzQu9Kx6J98GdGnXfxrHhqzU6239 intact-crc:E2296CC79FCA2BC6|rigid:aZa+L0+ZS3U30e6sNJa83HijA20 false sufficient binding region:62-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:G5EGI2 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-6541649|ensemblmetazoa:Y38C1BA.2a.1 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:g5egi2_caeel(display_long)|uniprotkb:Y38C1BA.2(orf name)|uniprotkb:snn-1(gene name)|psi-mi:snn-1(display_short)|uniprotkb:syn(gene name synonym)|uniprotkb:CELE_Y38C1BA.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545963|imex:IM-18681-1007 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) ensemblmetazoa:WBGene00004913(gene)|ensemblmetazoa:Y38C1BA.2a.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0046872"(metal ion binding)|refseq:NP_741327.1|wormbase:Y38C1BA.2a|interpro:IPR001359(Synapsin)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020897|interpro:IPR020898|uniprotkb:G5EGI2(identity)|wormbase:WBGene00004913(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:MH29+7Es7PNDOIE7j5XuTk9zSVY6239 intact-crc:99BEA538D160B56D|rigid:cXL+hmESkczkl8GU7a3etqhNn5s false sufficient binding region:62-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:Q9NA61 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545978|imex:IM-18681-1008 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 intact-crc:EC224421E41E8803|rigid:oS5Vfcn0H5np801Y92N6fhaidcw false sufficient binding region:62-126 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEQ3 uniprotkb:Q9N415 intact:EBI-319723|ensemblmetazoa:ZK1053.5.1 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 psi-mi:g5eeq3_caeel(display_long)|uniprotkb:scrm-2(gene name)|psi-mi:scrm-2(display_short)|uniprotkb:SCRM-2(gene name synonym)|uniprotkb:CELE_ZK1053.5(orf name)|uniprotkb:ZK1053.5(orf name) psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6545993|imex:IM-18681-1009 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O18289(uniprot-removed-ac)|ensemblmetazoa:WBGene00014200(gene)|ensemblmetazoa:ZK1053.5.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017128"(phospholipid scramblase activity)|interpro:IPR005552(Scramblase)|refseq:NP_493321.1|interpro:IPR025659|wormbase:ZK1053.5|uniprotkb:G5EEQ3(identity)|wormbase:WBGene00014200(identity) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:ayiWZFoWx+GH3NI47lKkWqbGlYY6239 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 intact-crc:F780B6A7FAC2201B|rigid:jsoiNwTFSlUOUtLcUlbAKmuuE58 false - sufficient binding region:62-126 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:Q17865 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546008|imex:IM-18681-1010 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 53|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:1344D17FC484D4F9|rigid:RtBZNYhi8VdEOFqt3HRiwEGT0U0 false sufficient binding region:816-879 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N415 uniprotkb:Q17865 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546023|imex:IM-18681-1011 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 50|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:F773E498671666A3|rigid:RtBZNYhi8VdEOFqt3HRiwEGT0U0 false sufficient binding region:1152-1216 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91529 uniprotkb:Q9N415 intact:EBI-6546038|ensemblmetazoa:W09C3.4.1 intact:EBI-6538150|ensemblmetazoa:Y39A3CL.2.1 psi-mi:rpc6_caeel(display_long)|uniprotkb:DNA-directed RNA polymerase III subunit F(gene name synonym)|uniprotkb:W09C3.4(orf name) psi-mi:q9n415_caeel(display_long)|uniprotkb:rimb-1(gene name)|psi-mi:rimb-1(display_short)|uniprotkb:tag-168(gene name synonym)|uniprotkb:CELE_Y39A3CL.2(orf name)|uniprotkb:Y39A3CL.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546040|imex:IM-18681-1012 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:W09C3.4.1(transcript)|ensemblmetazoa:WBGene00021112(gene)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0006383"(transcription by RNA polymerase III)|interpro:IPR007832(RNA polymerase Rpc34)|interpro:IPR016049(RNA polymerase Rpc34-like)|refseq:NP_491427.1|wormbase:W09C3.4|interpro:IPR036388|interpro:IPR036390|uniprotkb:P91529(identity)|wormbase:WBGene00021112(identity) ensemblmetazoa:WBGene00006513(gene)|ensemblmetazoa:Y39A3CL.2.1(transcript)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0045202"(synapse)|refseq:NP_497459.3|interpro:IPR001452(Src homology-3)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|wormbase:Y39A3CL.2|interpro:IPR035753|interpro:IPR035755|interpro:IPR036028|interpro:IPR036116|interpro:IPR040325|reactome:R-CEL-181429|reactome:R-CEL-181430|reactome:R-CEL-196108|reactome:R-CEL-210500|reactome:R-CEL-212676|reactome:R-CEL-264642|uniprotkb:Q9N415(identity)|wormbase:WBGene00006513(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2015/12/04 rogid:Z2o8BzKbkuZatWcaPPAkRbpVj4I6239 rogid:sjnPshjcLDe/n7T1pIPQax9iQQU6239 intact-crc:3C2B4C3C6C6E06E9|rigid:29P+g+hvIPPjUr6+j/N7PCl/f90 false - sufficient binding region:1152-1216 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44820 uniprotkb:Q9NHC3 intact:EBI-318098|ensemblmetazoa:F52C6.3.1 intact:EBI-6390681|ensemblmetazoa:Y41D4B.13a.1 psi-mi:o44820_caeel(display_long)|uniprotkb:F52C6.3(orf name)|uniprotkb:CELE_F52C6.3(orf name) psi-mi:ced2_caeel(display_long)|uniprotkb:ced-2(gene name)|psi-mi:ced-2(display_short)|uniprotkb:Cell-corpse engulfment protein CED-2(gene name synonym)|uniprotkb:Y41D4B.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546055|imex:IM-18681-1013 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494127.2|wormbase:F52C6.3|ensemblmetazoa:F52C6.3.1(transcript)|ensemblmetazoa:WBGene00018660(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|go:"GO:0016567"(protein ubiquitination)|dip:DIP-24316N|uniprotkb:O44820(identity)|wormbase:WBGene00018660(identity) ensemblmetazoa:WBGene00000416(gene)|ensemblmetazoa:Y41D4B.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0012501"(programmed cell death)|go:"GO:0016477"(cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|rcsb pdb:3QWX|rcsb pdb:3QWY|reactome:R-CEL-186763|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-8849471|reactome:R-CEL-912631|refseq:NP_500105.1|wormbase:Y41D4B.13a|dip:DIP-25408N|uniprotkb:Q9NHC3(identity)|wormbase:WBGene00000416(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:QuJ7/jGkBkfQqUUmrAJ8OuPtJUo6239 rogid:j5cxzcKENbxLxYp0CEUCAXlsmTk6239 intact-crc:BFB1C1D9ECCF05F5|rigid:7pFm7hJv/+6ytQD1RPdowiofAds false - sufficient binding region:119-175 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10457 uniprotkb:Q9NHC3 intact:EBI-311886|ensemblmetazoa:B0286.3.1 intact:EBI-6390681|ensemblmetazoa:Y41D4B.13a.1 psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:ced2_caeel(display_long)|uniprotkb:ced-2(gene name)|psi-mi:ced-2(display_short)|uniprotkb:Cell-corpse engulfment protein CED-2(gene name synonym)|uniprotkb:Y41D4B.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546070|imex:IM-18681-1014 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) ensemblmetazoa:WBGene00000416(gene)|ensemblmetazoa:Y41D4B.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0012501"(programmed cell death)|go:"GO:0016477"(cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|rcsb pdb:3QWX|rcsb pdb:3QWY|reactome:R-CEL-186763|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-8849471|reactome:R-CEL-912631|refseq:NP_500105.1|wormbase:Y41D4B.13a|dip:DIP-25408N|uniprotkb:Q9NHC3(identity)|wormbase:WBGene00000416(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 rogid:j5cxzcKENbxLxYp0CEUCAXlsmTk6239 intact-crc:2FB31E40B92795C8|rigid:I351ziTtAA5t9GXFusuPD+SGcgs false - sufficient binding region:219-276 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22387 uniprotkb:G5EC32 intact:EBI-320525|ensemblmetazoa:T11B7.1.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:q22387_caeel(display_long)|uniprotkb:T11B7.1(orf name)|uniprotkb:CELE_T11B7.1(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546085|imex:IM-18681-1015 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501530.1|wormbase:T11B7.1|ensemblmetazoa:T11B7.1.1(transcript)|ensemblmetazoa:WBGene00011706(gene)|dip:DIP-25021N|uniprotkb:Q22387(identity)|wormbase:WBGene00011706(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:g+qVF2x1tQiPg+8nyASbdemvmIA6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:201ED9D668369CD6|rigid:0yH6ba4fSd13jgYiCdvD3cKJgCo false - sufficient binding region:89-144 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B1Q247 uniprotkb:G5EC32 intact:EBI-2316099|ensemblmetazoa:B0507.3b.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:b1q247_caeel(display_long)|uniprotkb:CELE_B0507.3(orf name)|uniprotkb:B0507.3(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546100|imex:IM-18681-1016 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041077.1|wormbase:B0507.3b|ensemblmetazoa:B0507.3b.1(transcript)|ensemblmetazoa:WBGene00015220(gene)|uniprotkb:B1Q247(identity)|wormbase:WBGene00015220(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:kBIurKmudPti6cwGgEZ2n3mxWxI6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:2B2F15FF31051CC5|rigid:WZBuxW5rUpLgaV2XE1ZWCMNPLqw false - sufficient binding region:151-207 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q17795 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-2316131|ensemblmetazoa:C07G1.4a.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:q17795_caeel(display_long)|uniprotkb:wsp-1(gene name)|psi-mi:wsp-1(display_short)|uniprotkb:CELE_C07G1.4(orf name)|uniprotkb:C07G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546115|imex:IM-18681-1017 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_741459.2|wormbase:C07G1.4a|interpro:IPR000697(EVH1)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR033927|interpro:IPR036936|interpro:IPR030214|ensemblmetazoa:C07G1.4a.1(transcript)|ensemblmetazoa:WBGene00006957(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|uniprotkb:Q17795(identity)|wormbase:WBGene00006957(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:YBTDOwM+8a5vUAiihYM6ezASlGY6239 intact-crc:B8D726E2A66FFF8F|rigid:0uoubAHQyPhhF0aR+6yTQ1WFOcI false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:G5EC32 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546130|imex:IM-18681-1018 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:9AD63BC2FB7249ED|rigid:1czevcAqxE6Xv/WTTJk2lwhehRM false - sufficient binding region:151-207 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17583 uniprotkb:G5EC32 intact:EBI-313389|uniprotkb:Q9XZQ5|ensemblmetazoa:C09H6.2a.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:lin10_caeel(display_long)|uniprotkb:lin-10(gene name)|psi-mi:lin-10(display_short)|uniprotkb:C09H6.2(orf name)|uniprotkb:Abnormal cell lineage protein 10(gene name synonym) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546145|imex:IM-18681-1019 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020996.1|refseq:NP_492226.2|wormbase:C09H6.2a|wormbase:C09H6.2b|ensemblmetazoa:C09H6.2a.1(transcript)|ensemblmetazoa:WBGene00002999(gene)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0008104"(protein localization)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043058"(regulation of backward locomotion)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:1902946"(protein localization to early endosome)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|go:"GO:1905852"(positive regulation of backward locomotion)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|go:"GO:0030140"(trans-Golgi network transport vesicle)|reactome:R-CEL-212676|dip:DIP-24889N|uniprotkb:O17583(identity)|wormbase:WBGene00002999(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 13|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:Jf79hZqq2OhYFyo9bRA/bwZ2Cy06239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:4850743075AA6E95|rigid:oF9uXiqq8RAEZHjZtB915bCWzJQ false - sufficient binding region:151-207 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q9XZI6 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-311866|uniprotkb:Q95Q72|uniprotkb:Q95Q73|uniprotkb:Q95Q74|uniprotkb:Q95Q75|uniprotkb:Q9UA04|uniprotkb:Q9UA05|uniprotkb:Q9XZI7|uniprotkb:Q9XZI8|uniprotkb:Q9XZI9|ensemblmetazoa:C32E8.10a.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:pical_caeel(display_long)|uniprotkb:C32E8.10(orf name)|uniprotkb:unc-11(gene name)|psi-mi:unc-11(display_short)|uniprotkb:AP180-like adaptor protein(gene name synonym)|uniprotkb:Uncoordinated protein 11(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546160|imex:IM-18681-1020 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) ensemblmetazoa:C32E8.10a.1(transcript)|ensemblmetazoa:WBGene00006751(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0040011"(locomotion)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:1902683"(regulation of receptor localization to synapse)|go:"GO:1903539"(protein localization to postsynaptic membrane)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|refseq:NP_001021014.1|refseq:NP_001021015.1|refseq:NP_001021016.1|refseq:NP_491227.1|refseq:NP_491228.1|refseq:NP_491229.1|refseq:NP_491230.1|wormbase:C32E8.10a|wormbase:C32E8.10b|wormbase:C32E8.10c|wormbase:C32E8.10d|wormbase:C32E8.10e|wormbase:C32E8.10f|wormbase:C32E8.10h|reactome:R-CEL-432722|reactome:R-CEL-8856825|reactome:R-CEL-8856828|dip:DIP-25315N|uniprotkb:Q9XZI6(identity)|wormbase:WBGene00006751(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:4JQIZTgKSv8kTdP9aYTzoTQp6L06239 intact-crc:907E8CAA750DBEEE|rigid:lCBvjdSt5ADHsW3Xv7LcdgrRw4E false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:O61701 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-6537266 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:o61701_caeel(display_long)|uniprotkb:cyk-1(gene name)|psi-mi:cyk-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546175|imex:IM-18681-1021 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) go:"GO:0003779"(actin binding)|go:"GO:0016043"(cellular component organization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|uniprotkb:O61701(identity)|wormbase:WBGene00000872(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 26|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:3tZm/rdSqLAK4eIpP1J9faYAo7w6239 intact-crc:269A8766B61CBF61|rigid:JFCbxLBhFAulffc33nL1WjOo+uk false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1XFY2 uniprotkb:G5EC32 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546190|imex:IM-18681-1022 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:02FDC3E989320F09|rigid:gcJ1QlugxXHnw+FN/yhLaDj8ALg false - sufficient binding region:151-207 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q20365 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-2417498|uniprotkb:Q94154|ensemblmetazoa:F43D9.2.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:rab33_caeel(display_long)|uniprotkb:rab-33(gene name)|psi-mi:rab-33(display_short)|uniprotkb:F43D9.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546205|imex:IM-18681-1023 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) interpro:IPR027417|refseq:NP_499314.1|wormbase:F43D9.2|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|reactome:R-CEL-6811438|reactome:R-CEL-8873719|reactome:R-CEL-8854214|interpro:IPR041822|ensemblmetazoa:F43D9.2.1(transcript)|ensemblmetazoa:WBGene00004283(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0032482"(Rab protein signal transduction)|uniprotkb:Q20365(identity)|wormbase:WBGene00004283(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:tCv8SWStDv4MBvzoRfbHAFTgKlk6239 intact-crc:570BDAB2B13BFB7D|rigid:+pp1wyxhP4rLM+m8z5FaeUZulzo false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:O45522 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-326566|ensemblmetazoa:F45B8.3.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:o45522_caeel(display_long)|uniprotkb:F45B8.3(orf name)|uniprotkb:CELE_F45B8.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546220|imex:IM-18681-1024 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_510481.1|wormbase:F45B8.3|ensemblmetazoa:F45B8.3.1(transcript)|ensemblmetazoa:WBGene00009720(gene)|dip:DIP-24796N|uniprotkb:O45522(identity)|wormbase:WBGene00009720(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:GO1lxROeXD3veFrBFOJZLre0f5E6239 intact-crc:33594B7B2773CDA5|rigid:oGGSkK5bAQOBQCteyfI7bd8PZHE false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q3Y407 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-2317687|uniprotkb:G4SJ35|ensemblmetazoa:F46H5.6.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:q3y407_caeel(display_long)|uniprotkb:grd-7(gene name)|psi-mi:grd-7(display_short)|uniprotkb:CELE_F46H5.6(orf name)|uniprotkb:F46H5.6(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546235|imex:IM-18681-1025 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) interpro:IPR007284(Ground-like region)|wormbase:F46H5.6|interpro:IPR003882(Pistil-specific extensin-like protein)|ensemblmetazoa:F46H5.6.1(transcript)|ensemblmetazoa:WBGene00001696(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007154"(cell communication)|uniprotkb:Q3Y407(identity)|wormbase:WBGene00001696(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:77+Ww780xL2+LUmBj5htUR6eidA6239 intact-crc:90AC736B401A5D5F|rigid:zT3MjwFPb8JUUvx0CrRXgeuaA/Q false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9TYU9 uniprotkb:G5EC32 intact:EBI-2317613|ensemblmetazoa:F58B6.2.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:exc6_caeel(display_long)|uniprotkb:exc-6(gene name)|psi-mi:exc-6(display_short)|uniprotkb:inft-1(gene name synonym)|uniprotkb:F58B6.2(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546250|imex:IM-18681-1026 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F58B6.2|interpro:IPR015425(Actin-binding FH2)|refseq:NP_497334.2|interpro:IPR042201|ensemblmetazoa:F58B6.2.1(transcript)|ensemblmetazoa:WBGene00019030(gene)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031941"(filamentous actin)|go:"GO:0035150"(regulation of tube size)|go:"GO:0060562"(epithelial tube morphogenesis)|go:"GO:1904531"(positive regulation of actin filament binding)|uniprotkb:Q9TYU9(identity)|wormbase:WBGene00019030(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:oV2XrZ7bWd6qxEDMLD8J4fuVobU6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:6D9B139273DD23EC|rigid:VwcISGbLw3YdMCdCz7H41pAd+U8 false - sufficient binding region:151-207 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:F5GUF0 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-6542338|ensemblmetazoa:R06C1.3b.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:f5guf0_caeel(display_long)|uniprotkb:R06C1.3(orf name)|uniprotkb:wve-1(gene name)|psi-mi:wve-1(display_short)|uniprotkb:CELE_R06C1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546265|imex:IM-18681-1027 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) ensemblmetazoa:R06C1.3b.1(transcript)|ensemblmetazoa:WBGene00006958(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031209"(SCAR complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|refseq:NP_001251762.1|wormbase:R06C1.3b|interpro:IPR028288|uniprotkb:F5GUF0(identity)|wormbase:WBGene00006958(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:Jmm0mWkD2Esf0E7aV7/qOpEnV906239 intact-crc:7F3407BF5421E3F7|rigid:orCA3oLXwM+IzWahajq+YpyrgNc false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q95QA6 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546280|imex:IM-18681-1028 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 intact-crc:CB6D56F0E74C3A12|rigid:8ghloBbsDhEVStx7xQ/ZY+JkkkY false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BKZ9 uniprotkb:G5EC32 intact:EBI-327986|intact:EBI-6542537|uniprotkb:H2L0Q7|uniprotkb:H2L0Q8|uniprotkb:Q8WQE2|ensemblmetazoa:Y54F10AM.2a.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:feh1_caeel(display_long)|uniprotkb:feh-1(gene name)|psi-mi:feh-1(display_short)|uniprotkb:Y54F10AM.2(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546295|imex:IM-18681-1029 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IA96(q8ia96_caeel)|refseq:NP_001022906.1|refseq:NP_001022907.1|refseq:NP_497578.4|wormbase:Y54F10AM.2a|wormbase:Y54F10AM.2b|wormbase:Y54F10AM.2c|ensemblmetazoa:WBGene00001410(gene)|ensemblmetazoa:Y54F10AM.2a.1(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007631"(feeding behavior)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR039576|dip:DIP-25952N|reactome:R-CEL-5693565|uniprotkb:Q8WQE2(identity)|wormbase:WBGene00001410(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:2Db9uUfwcM9MUGxTnhJ9ysYYef86239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:918CF59FDD33639D|rigid:YeYisRq134FdjvZvfiDPmsgWfO8 false - sufficient binding region:151-207 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:G5ED33 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546310|imex:IM-18681-1030 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 15|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:4067E958888A173F|rigid:LOQMtSD/YX3RvdS5uOLsfiKz9dw false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q9BIF4 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546325|imex:IM-18681-1031 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 43|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 intact-crc:BA26A176D4F7FC05|rigid:KqbSdVP4/A6UzHcWUJiHy/PkTiM false sufficient binding region:151-207 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:O01481 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-2316191|ensemblmetazoa:C06A5.8a.1|ensemblmetazoa:C06A5.8a.2 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:o01481_caeel(display_long)|uniprotkb:CELE_C06A5.8(orf name)|uniprotkb:C06A5.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546340|imex:IM-18681-1032 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_491737.1|wormbase:C06A5.8a|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|ensemblmetazoa:C06A5.8a.1(transcript)|ensemblmetazoa:C06A5.8a.2(transcript)|ensemblmetazoa:WBGene00015505(gene)|go:"GO:0046872"(metal ion binding)|uniprotkb:O01481(identity)|wormbase:WBGene00015505(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 34|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:Ekx0URCP9yKkM2/26XixY6l2+Oc6239 intact-crc:D7513CBFAD969CC2|rigid:GoeZee1wBqkl0qSIGiN8u4VZ8c8 false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q17744 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-2315966|ensemblmetazoa:F43B10.1c.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:q17744_caeel(display_long)|uniprotkb:CELE_F43B10.1(orf name)|uniprotkb:F43B10.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546355|imex:IM-18681-1033 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) interpro:IPR011992(EF-Hand type)|interpro:IPR018247|wormbase:F43B10.1c|refseq:NP_001257277.1|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR041534|ensemblmetazoa:F43B10.1c.1(transcript)|ensemblmetazoa:WBGene00018373(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|uniprotkb:Q17744(identity)|wormbase:WBGene00015548(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:yBu4mQzQP54tuujYZMZhAIVmquE6239 intact-crc:244D845287B6F032|rigid:jjNvdHuE3yIg/dv7eIyUQxycyec false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17746 uniprotkb:G5EC32 intact:EBI-313792|ensemblmetazoa:C06G3.6.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:q17746_caeel(display_long)|uniprotkb:C06G3.6(orf name)|uniprotkb:CELE_C06G3.6(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546370|imex:IM-18681-1034 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501086.1|wormbase:C06G3.6|ensemblmetazoa:C06G3.6.1(transcript)|ensemblmetazoa:WBGene00015552(gene)|go:"GO:0000423"(mitophagy)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016235"(aggresome)|go:"GO:0035973"(aggrephagy)|go:"GO:0044753"(amphisome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR043145|reactome:R-CEL-5205685|dip:DIP-25290N|uniprotkb:Q17746(identity)|wormbase:WBGene00015552(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:jL1tM1UDvksdoV9mXL9cgz0MfTU6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:389497A1691D0A9E|rigid:abCrRdU55LCyNvFQ93x0UrLco5E false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17795 uniprotkb:G5EC32 intact:EBI-2316131|ensemblmetazoa:C07G1.4a.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:q17795_caeel(display_long)|uniprotkb:wsp-1(gene name)|psi-mi:wsp-1(display_short)|uniprotkb:CELE_C07G1.4(orf name)|uniprotkb:C07G1.4(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546385|imex:IM-18681-1035 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741459.2|wormbase:C07G1.4a|interpro:IPR000697(EVH1)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR033927|interpro:IPR036936|interpro:IPR030214|ensemblmetazoa:C07G1.4a.1(transcript)|ensemblmetazoa:WBGene00006957(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|uniprotkb:Q17795(identity)|wormbase:WBGene00006957(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:YBTDOwM+8a5vUAiihYM6ezASlGY6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:B1D32859AF36B258|rigid:0uoubAHQyPhhF0aR+6yTQ1WFOcI false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:G5EC32 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546400|imex:IM-18681-1036 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 23|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:3F3139F33169477E|rigid:1czevcAqxE6Xv/WTTJk2lwhehRM false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34400 uniprotkb:G5EC32 intact:EBI-2315872|uniprotkb:P34386|uniprotkb:P34403|uniprotkb:Q7JQ80|uniprotkb:Q8WT53|ensemblmetazoa:F10E9.6c.1|ensemblmetazoa:F10E9.6c.2 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:mig10_caeel(display_long)|uniprotkb:mig-10(gene name)|psi-mi:mig-10(display_short)|uniprotkb:F10E9.6(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546415|imex:IM-18681-1037 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021248.1|refseq:NP_498821.2|refseq:NP_498822.2|wormbase:F10E9.6a|wormbase:F10E9.6b|wormbase:F10E9.6c|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000159(Ras-association)|interpro:IPR029071|reactome:R-CEL-354192|interpro:IPR039664|interpro:IPR039665|reactome:R-CEL-354194|reactome:R-CEL-5674135|ensemblmetazoa:F10E9.6c.1(transcript)|ensemblmetazoa:F10E9.6c.2(transcript)|ensemblmetazoa:WBGene00003243(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0007165"(signal transduction)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018991"(oviposition)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031941"(filamentous actin)|go:"GO:0032584"(growth cone membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0043204"(perikaryon)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099523"(presynaptic cytosol)|uniprotkb:P34400(identity)|wormbase:WBGene00003243(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:qni0Ph9hE7m4FAxHa2yRYfjO0qY6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:C511AAFDD5E15090|rigid:xXbZtFGkMBQIIJmaTUtdZIq6Kxo false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62203 uniprotkb:G5EC32 intact:EBI-320780|ensemblmetazoa:F32B4.4a.1|intact:EBI-6530763|uniprotkb:F5GUF6|uniprotkb:Q7Z0X2 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:phm2_caeel(display_long)|uniprotkb:phm-2(gene name)|psi-mi:phm-2(display_short)|uniprotkb:F32B4.4(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546430|imex:IM-18681-1038 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F32B4.4a|ensemblmetazoa:F32B4.4a.1(transcript)|ensemblmetazoa:WBGene00009314(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007586"(digestion)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036361|refseq:NP_001021441.1|refseq:NP_001251667.1|refseq:NP_001021440.2|dip:DIP-25849N|reactome:R-CEL-3899300|wormbase:F32B4.4b|wormbase:F32B4.4c|uniprotkb:F5GUF6(identity)|wormbase:WBGene00009314(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 15|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/03/02 rogid:69Kg/RUbe1gThWpe8yrWyt9o0bQ6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:B640944C33DFA579|rigid:B/HZpPJq55Z5mLlZhod/h2683u4 false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16299 uniprotkb:G5EC32 intact:EBI-320880|ensemblmetazoa:F32D1.1a.1|ensemblmetazoa:F32D1.1a.2 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:figl1_caeel(display_long)|uniprotkb:Fidgetin homolog(gene name synonym)|uniprotkb:F32D1.1(orf name)|uniprotkb:figl-1(gene name)|psi-mi:figl-1(display_short) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546445|imex:IM-18681-1039 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504197.1|ensemblmetazoa:F32D1.1a.1(transcript)|ensemblmetazoa:F32D1.1a.2(transcript)|ensemblmetazoa:WBGene00017981(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051301"(cell division)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|rcsb pdb:4L15|rcsb pdb:4L16|wormbase:F32D1.1a|dip:DIP-25869N|uniprotkb:O16299(identity)|wormbase:WBGene00017981(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 38|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:MNZcOTWKIrc/F728Rv8K1A5c43c6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:265154F579B87FEE|rigid:wMrhMqFxdsRSIJMeHvLlM1nscp8 false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q966J6 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-327612|ensemblmetazoa:F41B4.1.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:q966j6_caeel(display_long)|uniprotkb:F41B4.1(orf name)|uniprotkb:CELE_F41B4.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546460|imex:IM-18681-1040 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_509148.2|wormbase:F41B4.1|ensemblmetazoa:F41B4.1.1(transcript)|ensemblmetazoa:WBGene00018257(gene)|dip:DIP-26336N|uniprotkb:Q966J6(identity)|wormbase:WBGene00018257(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:daBFAeewQ1vhaxj4tlw0watbWpw6239 intact-crc:55632D41F1BF7DEC|rigid:2wlNWz/t1hpwAqnjfkfReSdew4c false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q20670 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-2316655|ensemblmetazoa:F52E10.4a.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:q20670_caeel(display_long)|uniprotkb:F52E10.4(orf name)|uniprotkb:CELE_F52E10.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546475|imex:IM-18681-1041 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_510653.1|wormbase:F52E10.4a|ensemblmetazoa:F52E10.4a.1(transcript)|ensemblmetazoa:WBGene00009935(gene)|uniprotkb:Q20670(identity)|wormbase:WBGene00009935(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:pLiUuYS8xjtw+8CYvfey48uV8m46239 intact-crc:60CB1C09787CBF78|rigid:6SrixjadKOYbgNlQzmPPNr2+IXg false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q03601 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-314158|uniprotkb:Q23510|ensemblmetazoa:F54G8.4a.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:nhl1_caeel(display_long)|uniprotkb:nhl-1(gene name)|psi-mi:nhl-1(display_short)|uniprotkb:F54G8.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546490|imex:IM-18681-1042 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) refseq:NP_499028.1|ensemblmetazoa:F54G8.4a.1(transcript)|ensemblmetazoa:WBGene00003597(gene)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030371"(translation repressor activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|wormbase:F54G8.4a|dip:DIP-26359N|uniprotkb:Q03601(identity)|wormbase:WBGene00003597(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 26|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:vg7P1U2gPP4ytoSs2LQ+HsIi60Q6239 intact-crc:43C68C04A70CCE2D|rigid:fWIROZW6E8uRXaUv54MF10mvzqA false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q8I4H7 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-6536499|ensemblmetazoa:K02C4.5.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:q8i4h7_caeel(display_long)|uniprotkb:CELE_K02C4.5(orf name)|uniprotkb:K02C4.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546505|imex:IM-18681-1043 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) ensemblmetazoa:K02C4.5.1(transcript)|ensemblmetazoa:WBGene00010503(gene)|refseq:NP_495695.2|wormbase:K02C4.5|uniprotkb:Q8I4H7(identity)|wormbase:WBGene00010503(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:/psCM8S6y04pL8WA8ShGIWUwm4Q6239 intact-crc:1E635B1C592DC25B|rigid:apcfIRCLwVCBgdNaLyOTWw3UujU false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45681 uniprotkb:G5EC32 intact:EBI-2316236|ensemblmetazoa:K10H10.4a.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:o45681_caeel(display_long)|uniprotkb:CELE_K10H10.4(orf name)|uniprotkb:K10H10.4(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546520|imex:IM-18681-1044 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:K10H10.4a|refseq:NP_497010.2|ensemblmetazoa:K10H10.4a.1(transcript)|ensemblmetazoa:WBGene00010760(gene)|uniprotkb:O45681(identity)|wormbase:WBGene00010760(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:A2bBnhSPE+YaCuVko69q1iq9vyM6239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:955F7B528C29D96C|rigid:oLMlFBrnR6AdSsYs1KJTUyUoYxM false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19019 uniprotkb:G5EC32 intact:EBI-315356|ensemblmetazoa:M02A10.3a.1 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 psi-mi:q19019_caeel(display_long)|uniprotkb:sli-1(gene name)|psi-mi:sli-1(display_short)|uniprotkb:CELE_M02A10.3(orf name)|uniprotkb:M02A10.3(orf name) psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546535|imex:IM-18681-1045 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-8849469|refseq:NP_508145.2|wormbase:M02A10.3a|reactome:R-CEL-1433559|reactome:R-CEL-182971|reactome:R-CEL-912631|reactome:R-CEL-983168|ensemblmetazoa:M02A10.3a.1(transcript)|ensemblmetazoa:WBGene00004829(gene)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0045121"(membrane raft)|go:"GO:0047690"(aspartyltransferase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR017907|interpro:IPR018247|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|reactome:R-CEL-6807004|dip:DIP-25788N|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:Q19019(identity)|wormbase:WBGene00004829(identity) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:/BtQ1wHY5H3olzNJgVCi9T+2aj86239 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 intact-crc:6A11037269AB56E7|rigid:OOezcvVpQOKzTBhAXNaNKTjPWuo false - sufficient binding region:352-408 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q22002 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-2316177|ensemblmetazoa:R166.1a.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:mab10_caeel(display_long)|uniprotkb:mab-10(gene name)|psi-mi:mab-10(display_short)|uniprotkb:Protein male abnormal 10(gene name synonym)|uniprotkb:R166.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546550|imex:IM-18681-1046 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) interpro:IPR006989(Nab, central region)|interpro:IPR006988(Nab, N-terminal)|interpro:IPR038398|wormbase:R166.1a|refseq:NP_496268.2|interpro:IPR039040|reactome:R-CEL-9031628|ensemblmetazoa:R166.1a.1(transcript)|ensemblmetazoa:WBGene00003107(gene)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010458"(exit from mitosis)|go:"GO:0022404"(molting cycle process)|go:"GO:0040028"(regulation of vulval development)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|uniprotkb:Q22002(identity)|wormbase:WBGene00003107(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:zhw1NK4weat9xTi6VsVXhJSaq+o6239 intact-crc:83067A2E51972285|rigid:lpD7H3TjZ6VORv1SUOTvr64Dzmg false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:Q95QA6 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546565|imex:IM-18681-1047 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 intact-crc:91CD0FB64C63BE00|rigid:8ghloBbsDhEVStx7xQ/ZY+JkkkY false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:G5EGI2 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-6541649|ensemblmetazoa:Y38C1BA.2a.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:g5egi2_caeel(display_long)|uniprotkb:Y38C1BA.2(orf name)|uniprotkb:snn-1(gene name)|psi-mi:snn-1(display_short)|uniprotkb:syn(gene name synonym)|uniprotkb:CELE_Y38C1BA.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546580|imex:IM-18681-1048 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) ensemblmetazoa:WBGene00004913(gene)|ensemblmetazoa:Y38C1BA.2a.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0046872"(metal ion binding)|refseq:NP_741327.1|wormbase:Y38C1BA.2a|interpro:IPR001359(Synapsin)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020897|interpro:IPR020898|uniprotkb:G5EGI2(identity)|wormbase:WBGene00004913(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:MH29+7Es7PNDOIE7j5XuTk9zSVY6239 intact-crc:D91CE640846F644C|rigid:oZKhCbuhY7OUTPINn245gzg6TWc false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EC32 uniprotkb:G5ED33 intact:EBI-325337|ensemblmetazoa:Y45F10D.13a.1|intact:EBI-6534380|uniprotkb:O62482 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:srbs1_caeel(display_long)|uniprotkb:sorb-1(gene name)|psi-mi:sorb-1(display_short)|uniprotkb:Y45F10D.13(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546595|imex:IM-18681-1049 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y45F10D.13c|refseq:NP_001255756.1|ensemblmetazoa:WBGene00012891(gene)|ensemblmetazoa:Y45F10D.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0097433"(dense body)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR036028|go:"GO:0045214"(sarcomere organization)|dip:DIP-24971N|refseq:NP_001041035.2|wormbase:Y45F10D.13a|reactome:R-CEL-445355|uniprotkb:G5EC32(identity)|wormbase:WBGene00012891(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/08/05 rogid:fZd4RVXZUpoJeJGtRXjxzU4hWr06239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:F180E965699726A5|rigid:LOQMtSD/YX3RvdS5uOLsfiKz9dw false sufficient binding region:352-408 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDZ2 uniprotkb:Q8IAA6 intact:EBI-313698|ensemblmetazoa:T07C4.1.1|ensemblmetazoa:T07C4.1.2 intact:EBI-6539901|ensemblmetazoa:Y47G6A.5b.1 psi-mi:umps_caeel(display_long)|uniprotkb:umps-1(gene name)|psi-mi:umps-1(display_short)|uniprotkb:rad-6(gene name synonym)|uniprotkb:T07C4.1(orf name) psi-mi:q8iaa6_caeel(display_long)|uniprotkb:CELE_Y47G6A.5(orf name)|uniprotkb:Y47G6A.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546610|imex:IM-18681-1050 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q18516(uniprot-removed-ac)|interpro:IPR001754(Orotidine 5'-phosphate decarboxylase, core)|interpro:IPR004467(Orotate phosphoribosyl transferase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR014732(Orotidine 5'-phosphate decarboxylase, subfamily 1, core)|interpro:IPR023031|refseq:NP_499291.1|mint:G5EDZ2|wormbase:T07C4.1|ensemblmetazoa:T07C4.1.1(transcript)|ensemblmetazoa:T07C4.1.2(transcript)|ensemblmetazoa:WBGene00011559(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0004588"(orotate phosphoribosyltransferase activity)|go:"GO:0004590"(orotidine-5'-phosphate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006222"(UMP biosynthetic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009411"(response to UV)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0090727"(positive regulation of brood size)|reactome:R-CEL-500753|interpro:IPR029057|interpro:IPR000836(Phosphoribosyltransferase)|uniprotkb:G5EDZ2(identity)|wormbase:WBGene00011559(identity) ensemblmetazoa:WBGene00021635(gene)|ensemblmetazoa:Y47G6A.5b.1(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045087"(innate immune response)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_871806.1|wormbase:Y47G6A.5b|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q8IAA6(identity)|wormbase:WBGene00021635(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Cpk0wa1uimBSN+c829/7jJMJdLk6239 rogid:SvM+G9pYBBl1bFy0y3N8GPbnwCk6239 intact-crc:AE154CDAB4A5EB19|rigid:dQWzNMI6dPtws9+TvdQG1Fzq7kk false - sufficient binding region:97-154 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XW5 uniprotkb:Q10457 intact:EBI-2317194|ensemblmetazoa:Y55B1BR.4.1 intact:EBI-311886|ensemblmetazoa:B0286.3.1 psi-mi:q95xw5_caeel(display_long)|uniprotkb:magu-1(gene name)|psi-mi:magu-1(display_short)|uniprotkb:Y55B1BR.4(orf name)|uniprotkb:CELE_Y55B1BR.4(orf name) psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546625|imex:IM-18681-1051 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497201.1|wormbase:Y55B1BR.4|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013406|interpro:IPR036028|interpro:IPR036034|ensemblmetazoa:WBGene00021914(gene)|ensemblmetazoa:Y55B1BR.4.1(transcript)|uniprotkb:Q95XW5(identity)|wormbase:WBGene00021914(identity) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:aVqXWeyfbEeIB7tFxhAuoVNRsrM6239 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 intact-crc:F0E4FD86F6472836|rigid:2Yi+XrnynepeL+463bem4cHdw+o false sufficient binding region:223-305 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XZI6 uniprotkb:Q95XW5 intact:EBI-311866|uniprotkb:Q95Q72|uniprotkb:Q95Q73|uniprotkb:Q95Q74|uniprotkb:Q95Q75|uniprotkb:Q9UA04|uniprotkb:Q9UA05|uniprotkb:Q9XZI7|uniprotkb:Q9XZI8|uniprotkb:Q9XZI9|ensemblmetazoa:C32E8.10a.1 intact:EBI-2317194|ensemblmetazoa:Y55B1BR.4.1 psi-mi:pical_caeel(display_long)|uniprotkb:C32E8.10(orf name)|uniprotkb:unc-11(gene name)|psi-mi:unc-11(display_short)|uniprotkb:AP180-like adaptor protein(gene name synonym)|uniprotkb:Uncoordinated protein 11(gene name synonym) psi-mi:q95xw5_caeel(display_long)|uniprotkb:magu-1(gene name)|psi-mi:magu-1(display_short)|uniprotkb:Y55B1BR.4(orf name)|uniprotkb:CELE_Y55B1BR.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546640|imex:IM-18681-1052 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C32E8.10a.1(transcript)|ensemblmetazoa:WBGene00006751(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0040011"(locomotion)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:1902683"(regulation of receptor localization to synapse)|go:"GO:1903539"(protein localization to postsynaptic membrane)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|refseq:NP_001021014.1|refseq:NP_001021015.1|refseq:NP_001021016.1|refseq:NP_491227.1|refseq:NP_491228.1|refseq:NP_491229.1|refseq:NP_491230.1|wormbase:C32E8.10a|wormbase:C32E8.10b|wormbase:C32E8.10c|wormbase:C32E8.10d|wormbase:C32E8.10e|wormbase:C32E8.10f|wormbase:C32E8.10h|reactome:R-CEL-432722|reactome:R-CEL-8856825|reactome:R-CEL-8856828|dip:DIP-25315N|uniprotkb:Q9XZI6(identity)|wormbase:WBGene00006751(identity) refseq:NP_497201.1|wormbase:Y55B1BR.4|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013406|interpro:IPR036028|interpro:IPR036034|ensemblmetazoa:WBGene00021914(gene)|ensemblmetazoa:Y55B1BR.4.1(transcript)|uniprotkb:Q95XW5(identity)|wormbase:WBGene00021914(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4JQIZTgKSv8kTdP9aYTzoTQp6L06239 rogid:aVqXWeyfbEeIB7tFxhAuoVNRsrM6239 intact-crc:C4869D452EA4DB64|rigid:fp6BuvDDMycJakHERof3XDLG76s false - sufficient binding region:223-305 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XW5 uniprotkb:H2KZZ2 intact:EBI-2317194|ensemblmetazoa:Y55B1BR.4.1 intact:EBI-2420815|intact:EBI-6765823|intact:EBI-6541491|uniprotkb:A0A2X0RWL7|uniprotkb:A0A2X0T4B7|uniprotkb:H2KZZ0|uniprotkb:H2KZZ1|uniprotkb:H2KZZ3|uniprotkb:H2KZZ4|uniprotkb:Q5TYL0|uniprotkb:Q86MJ3|uniprotkb:Q86MJ4|ensemblmetazoa:W02C12.3c.1 psi-mi:q95xw5_caeel(display_long)|uniprotkb:magu-1(gene name)|psi-mi:magu-1(display_short)|uniprotkb:Y55B1BR.4(orf name)|uniprotkb:CELE_Y55B1BR.4(orf name) psi-mi:hlh30_caeel(display_long)|uniprotkb:hlh-30(gene name)|psi-mi:hlh-30(display_short)|uniprotkb:W02C12.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546655|imex:IM-18681-1053 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497201.1|wormbase:Y55B1BR.4|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013406|interpro:IPR036028|interpro:IPR036034|ensemblmetazoa:WBGene00021914(gene)|ensemblmetazoa:Y55B1BR.4.1(transcript)|uniprotkb:Q95XW5(identity)|wormbase:WBGene00021914(identity) uniprotkb:Q95ZK5(uniprot-removed-ac)|reactome:R-CEL-3232118|refseq:NP_001023411.1|wormbase:W02C12.3a|wormbase:W02C12.3c|wormbase:W02C12.3d|wormbase:W02C12.3e|wormbase:W02C12.3f|wormbase:W02C12.3g|wormbase:W02C12.3h|wormbase:W02C12.3i|wormbase:W02C12.3j|interpro:IPR011598(Helix-loop-helix DNA-binding)|wormbase:W02C12.3b|interpro:IPR036638|refseq:NP_001023412.1|refseq:NP_001023413.1|refseq:NP_001023414.1|refseq:NP_001023415.1|refseq:NP_001023416.1|refseq:NP_500461.1|refseq:NP_500462.1|ensemblmetazoa:W02C12.3c.1(transcript)|ensemblmetazoa:WBGene00020930(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:1905686"(positive regulation of plasma membrane repair)|uniprotkb:Q5TYL0(identity)|wormbase:WBGene00020930(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2021/02/11 rogid:aVqXWeyfbEeIB7tFxhAuoVNRsrM6239 rogid:iGZh0KT07VIYofGovWOZj0raCt06239 intact-crc:C34C30159EA391B5|rigid:0n0gMVSsEIJQ5C1Mgc7SCS25aR0 false sufficient binding region:223-305 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XW5 uniprotkb:Q9NA61 intact:EBI-2317194|ensemblmetazoa:Y55B1BR.4.1 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 psi-mi:q95xw5_caeel(display_long)|uniprotkb:magu-1(gene name)|psi-mi:magu-1(display_short)|uniprotkb:Y55B1BR.4(orf name)|uniprotkb:CELE_Y55B1BR.4(orf name) psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546670|imex:IM-18681-1054 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497201.1|wormbase:Y55B1BR.4|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013406|interpro:IPR036028|interpro:IPR036034|ensemblmetazoa:WBGene00021914(gene)|ensemblmetazoa:Y55B1BR.4.1(transcript)|uniprotkb:Q95XW5(identity)|wormbase:WBGene00021914(identity) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:aVqXWeyfbEeIB7tFxhAuoVNRsrM6239 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 intact-crc:23E34F48291CE011|rigid:RqvZGejClSdWWPp9rHJ5kGh+LQs false sufficient binding region:223-305 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEC6 uniprotkb:Q95XW5 intact:EBI-313826|ensemblmetazoa:F07B7.7.1 intact:EBI-2317194|ensemblmetazoa:Y55B1BR.4.1 psi-mi:g5eec6_caeel(display_long)|uniprotkb:F07B7.7(orf name)|uniprotkb:CELE_F07B7.7(orf name) psi-mi:q95xw5_caeel(display_long)|uniprotkb:magu-1(gene name)|psi-mi:magu-1(display_short)|uniprotkb:Y55B1BR.4(orf name)|uniprotkb:CELE_Y55B1BR.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546685|imex:IM-18681-1055 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q23301(uniprot-removed-ac)|refseq:NP_505272.1|refseq:NP_505287.1|wormbase:F07B7.7|ensemblmetazoa:F07B7.7.1(transcript)|ensemblmetazoa:WBGene00017188(gene)|uniprotkb:G5EEC6(identity)|wormbase:WBGene00022607(identity) refseq:NP_497201.1|wormbase:Y55B1BR.4|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013406|interpro:IPR036028|interpro:IPR036034|ensemblmetazoa:WBGene00021914(gene)|ensemblmetazoa:Y55B1BR.4.1(transcript)|uniprotkb:Q95XW5(identity)|wormbase:WBGene00021914(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:9GuWi0445TwR5VBFwvv6vOeWQgc6239 rogid:aVqXWeyfbEeIB7tFxhAuoVNRsrM6239 intact-crc:4108E3CF7533DD79|rigid:9sRt2Umz8ylKao/ay66/eyclyZg false - sufficient binding region:223-305 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XW5 uniprotkb:O16684 intact:EBI-2317194|ensemblmetazoa:Y55B1BR.4.1 intact:EBI-2317242|ensemblmetazoa:ZK1240.1.1 psi-mi:q95xw5_caeel(display_long)|uniprotkb:magu-1(gene name)|psi-mi:magu-1(display_short)|uniprotkb:Y55B1BR.4(orf name)|uniprotkb:CELE_Y55B1BR.4(orf name) psi-mi:o16684_caeel(display_long)|uniprotkb:ZK1240.1(orf name)|uniprotkb:CELE_ZK1240.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546700|imex:IM-18681-1056 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497201.1|wormbase:Y55B1BR.4|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013406|interpro:IPR036028|interpro:IPR036034|ensemblmetazoa:WBGene00021914(gene)|ensemblmetazoa:Y55B1BR.4.1(transcript)|uniprotkb:Q95XW5(identity)|wormbase:WBGene00021914(identity) refseq:NP_494243.2|wormbase:ZK1240.1|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|ensemblmetazoa:WBGene00022866(gene)|ensemblmetazoa:ZK1240.1.1(transcript)|go:"GO:0008270"(zinc ion binding)|uniprotkb:O16684(identity)|wormbase:WBGene00022866(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:aVqXWeyfbEeIB7tFxhAuoVNRsrM6239 rogid:LEpCwoEh6I0VbWmntoC06AaImN86239 intact-crc:3EA92C8E4A8317D4|rigid:940ue7+2JFexKOn8wdjtGRl5XO0 false sufficient binding region:223-305 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED33 uniprotkb:Q11181 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 intact:EBI-2316016|uniprotkb:Q8T3F3|uniprotkb:Q8T3F4|uniprotkb:Q8T3F5|ensemblmetazoa:C05D10.4b.1 psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:ypc4_caeel(display_long)|uniprotkb:C05D10.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546715|imex:IM-18681-1057 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) refseq:NP_498323.2|refseq:NP_498324.2|refseq:NP_741170.1|wormbase:C05D10.4a|wormbase:C05D10.4b|wormbase:C05D10.4c|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|ensemblmetazoa:C05D10.4b.1(transcript)|ensemblmetazoa:WBGene00015480(gene)|uniprotkb:Q11181(identity)|wormbase:WBGene00015480(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 rogid:msS16ZOpmue9+9+to7VFLPE1TM86239 intact-crc:EE87B73449242D62|rigid:pi/hIo5HXfaxGaAWhRB60mNJ3oA false sufficient binding region:552-607 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q10457 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-311886|ensemblmetazoa:B0286.3.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546730|imex:IM-18681-1058 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 intact-crc:CC4A73678E3F6AF9|rigid:riqIj80uKzDDtAW2MewFiIha0t4 false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:P39055 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546745|imex:IM-18681-1059 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 42|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:34B2C109E8E0F59D|rigid:owBNvXGW7fWrc3Hl6/j2DOoy/PA false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q11181 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-2316016|uniprotkb:Q8T3F3|uniprotkb:Q8T3F4|uniprotkb:Q8T3F5|ensemblmetazoa:C05D10.4b.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:ypc4_caeel(display_long)|uniprotkb:C05D10.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546760|imex:IM-18681-1060 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_498323.2|refseq:NP_498324.2|refseq:NP_741170.1|wormbase:C05D10.4a|wormbase:C05D10.4b|wormbase:C05D10.4c|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|ensemblmetazoa:C05D10.4b.1(transcript)|ensemblmetazoa:WBGene00015480(gene)|uniprotkb:Q11181(identity)|wormbase:WBGene00015480(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:msS16ZOpmue9+9+to7VFLPE1TM86239 intact-crc:34B870CA27EB99A0|rigid:NocLkSsdQ6etXJhVm4bohtOVjVQ false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q17744 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-2315966|ensemblmetazoa:F43B10.1c.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q17744_caeel(display_long)|uniprotkb:CELE_F43B10.1(orf name)|uniprotkb:F43B10.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546775|imex:IM-18681-1061 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) interpro:IPR011992(EF-Hand type)|interpro:IPR018247|wormbase:F43B10.1c|refseq:NP_001257277.1|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR041534|ensemblmetazoa:F43B10.1c.1(transcript)|ensemblmetazoa:WBGene00018373(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|uniprotkb:Q17744(identity)|wormbase:WBGene00015548(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:yBu4mQzQP54tuujYZMZhAIVmquE6239 intact-crc:9D00771EB0509375|rigid:SSUROv+G4tZu/DaxjhXbecvlI/4 false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q17795 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-2316131|ensemblmetazoa:C07G1.4a.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q17795_caeel(display_long)|uniprotkb:wsp-1(gene name)|psi-mi:wsp-1(display_short)|uniprotkb:CELE_C07G1.4(orf name)|uniprotkb:C07G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546790|imex:IM-18681-1062 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_741459.2|wormbase:C07G1.4a|interpro:IPR000697(EVH1)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR033927|interpro:IPR036936|interpro:IPR030214|ensemblmetazoa:C07G1.4a.1(transcript)|ensemblmetazoa:WBGene00006957(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|uniprotkb:Q17795(identity)|wormbase:WBGene00006957(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:YBTDOwM+8a5vUAiihYM6ezASlGY6239 intact-crc:265814870EEDA5AA|rigid:6ku9P9uhWUG/GSqgmERkcD6gbj4 false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09442 uniprotkb:G5EE56 intact:EBI-2316106|uniprotkb:Q8T8N6|ensemblmetazoa:C08B11.5.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:sf3b4_caeel(display_long)|uniprotkb:sap-49(gene name)|psi-mi:sap-49(display_short)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:C08B11.5(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546805|imex:IM-18681-1063 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021932.1|wormbase:C08B11.5|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR034158|interpro:IPR034159|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C08B11.5.1(transcript)|ensemblmetazoa:WBGene00004723(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|uniprotkb:Q09442(identity)|wormbase:WBGene00004723(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 114|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:p9jCTRnhWRovZzYfWyL6TCdVmIs6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:20110B8C1EB7AD0A|rigid:iYkI6l2JDY64geSkGCjk4kU30eI false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q17865 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-317562|ensemblmetazoa:C09G1.4.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:yte4_caeel(display_long)|uniprotkb:C09G1.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546820|imex:IM-18681-1064 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) wormbase:C09G1.4|refseq:NP_510621.2|ensemblmetazoa:C09G1.4.1(transcript)|ensemblmetazoa:WBGene00007486(gene)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|go:"GO:0060341"(regulation of cellular localization)|dip:DIP-25627N|reactome:R-CEL-9013149|uniprotkb:Q17865(identity)|wormbase:WBGene00007486(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 17|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:lrBneMvaXtWYWY4O2UTvrg4rjIg6239 intact-crc:3D1B9F7C32619162|rigid:VzpDNuiFHTXy4FML+O9zL/t38s0 false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q18225 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6542980|ensemblmetazoa:C26E6.2.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:flh2_caeel(display_long)|uniprotkb:C26E6.2(orf name)|uniprotkb:flh-2(gene name)|psi-mi:flh-2(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546835|imex:IM-18681-1065 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:C26E6.2.1(transcript)|ensemblmetazoa:WBGene00016138(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR007588(Zinc finger, FLYWCH-type)|refseq:NP_498049.2|wormbase:C26E6.2|uniprotkb:Q18225(identity)|wormbase:WBGene00016138(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:H53A9H3CbM2l/HLncgbQ6QgA8Fg6239 intact-crc:6D38961DBF44C6BB|rigid:4IcX4faN242ASJfFNXScPM/8tU0 false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFZ9 uniprotkb:G5EE56 intact:EBI-6538931|ensemblmetazoa:C46H11.11a.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:g5efz9_caeel(display_long)|uniprotkb:C46H11.11(orf name)|uniprotkb:fhod-1(gene name)|psi-mi:fhod-1(display_short)|uniprotkb:CELE_C46H11.11(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546850|imex:IM-18681-1066 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C46H11.11a|ensemblmetazoa:C46H11.11a.1(transcript)|ensemblmetazoa:WBGene00016735(gene)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_491513.2|interpro:IPR042201|interpro:IPR041387|uniprotkb:G5EFZ9(identity)|wormbase:WBGene00016735(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:igG/LeOkDoPfWLC/32q7EkQRdUA6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:88B828B0C6A55A92|rigid:v5AUM9XBJcB25CS+aSpWluH7bwU false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QQ9 uniprotkb:G5EE56 intact:EBI-2317344|ensemblmetazoa:C49H3.6a.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q95qq9_caeel(display_long)|uniprotkb:C49H3.6(orf name)|uniprotkb:CELE_C49H3.6(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546865|imex:IM-18681-1067 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501316.2|wormbase:C49H3.6a|interpro:IPR019131|ensemblmetazoa:C49H3.6a.1(transcript)|ensemblmetazoa:WBGene00016792(gene)|go:"GO:0005737"(cytoplasm)|uniprotkb:Q95QQ9(identity)|wormbase:WBGene00016792(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 47|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:eHT6KUXkocreuSpbjuHpYT+s+tQ6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:BF6B35D527B5D9C2|rigid:q4cGkthvudTrs+BGnpC7c66AaI4 false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:O61701 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6537266 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:o61701_caeel(display_long)|uniprotkb:cyk-1(gene name)|psi-mi:cyk-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546880|imex:IM-18681-1068 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) go:"GO:0003779"(actin binding)|go:"GO:0016043"(cellular component organization)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|uniprotkb:O61701(identity)|wormbase:WBGene00000872(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 37|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:3tZm/rdSqLAK4eIpP1J9faYAo7w6239 intact-crc:FBB02106236CD046|rigid:vo/l/dALKVoNDIGXgwXN7SJwh4s false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86NH1 uniprotkb:G5EE56 intact:EBI-2415108|uniprotkb:Q86NH0|uniprotkb:Q8ISS1|ensemblmetazoa:F35D2.5a.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:syd1_caeel(display_long)|uniprotkb:Synapse defective protein 1(gene name synonym)|uniprotkb:Axon identity specification protein syd-1(gene name synonym)|uniprotkb:F35D2.5(orf name)|uniprotkb:syd-1(gene name)|psi-mi:syd-1(display_short) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546895|imex:IM-18681-1069 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022146.1|refseq:NP_001022148.1|refseq:NP_495592.2|wormbase:F35D2.5a|wormbase:F35D2.5b|wormbase:F35D2.5c|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9035034|interpro:IPR035892|interpro:IPR036034|ensemblmetazoa:F35D2.5a.1(transcript)|ensemblmetazoa:WBGene00006363(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0030030"(cell projection organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040011"(locomotion)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0048495"(Roundabout binding)|go:"GO:0090630"(activation of GTPase activity)|uniprotkb:Q86NH1(identity)|wormbase:WBGene00006363(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:UQO1xXX8Z02QSVi2Tv3vE7T/8QM6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:C948F77714D6CCB4|rigid:F/OJNGgmi/L2zF5htO4pdVHAfbs false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q1XFY2 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-2316564|ensemblmetazoa:F43B10.2b.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q1xfy2_caeel(display_long)|uniprotkb:F43B10.2(orf name)|uniprotkb:tag-343(gene name)|psi-mi:tag-343(display_short)|uniprotkb:CELE_F43B10.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546910|imex:IM-18681-1070 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_001041252.1|wormbase:F43B10.2b|interpro:IPR007133(RNA polymerase II-associated, Paf1)|ensemblmetazoa:F43B10.2b.1(transcript)|ensemblmetazoa:WBGene00018374(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|uniprotkb:Q1XFY2(identity)|wormbase:WBGene00018374(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 27|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:93FiykPMgLAQPOtvbpJAsNGYbFY6239 intact-crc:70B7F4C5A3AD7D0E|rigid:VGAbtcmj3w/vy54Be8aTLaeB40Q false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45522 uniprotkb:G5EE56 intact:EBI-326566|ensemblmetazoa:F45B8.3.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:o45522_caeel(display_long)|uniprotkb:F45B8.3(orf name)|uniprotkb:CELE_F45B8.3(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546925|imex:IM-18681-1071 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_510481.1|wormbase:F45B8.3|ensemblmetazoa:F45B8.3.1(transcript)|ensemblmetazoa:WBGene00009720(gene)|dip:DIP-24796N|uniprotkb:O45522(identity)|wormbase:WBGene00009720(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 21|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:GO1lxROeXD3veFrBFOJZLre0f5E6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:F9648866E3370C4E|rigid:Tp0tCfZy1nOPXsjFJ0KF3Dk9/es false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q3Y407 uniprotkb:G5EE56 intact:EBI-2317687|uniprotkb:G4SJ35|ensemblmetazoa:F46H5.6.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q3y407_caeel(display_long)|uniprotkb:grd-7(gene name)|psi-mi:grd-7(display_short)|uniprotkb:CELE_F46H5.6(orf name)|uniprotkb:F46H5.6(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546940|imex:IM-18681-1072 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007284(Ground-like region)|wormbase:F46H5.6|interpro:IPR003882(Pistil-specific extensin-like protein)|ensemblmetazoa:F46H5.6.1(transcript)|ensemblmetazoa:WBGene00001696(gene)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007154"(cell communication)|uniprotkb:Q3Y407(identity)|wormbase:WBGene00001696(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 31|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2019/01/23 rogid:77+Ww780xL2+LUmBj5htUR6eidA6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:333EC78C03C6F514|rigid:OVmAzd+hgo75fAI9Rx6qBj+IRTI false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q03601 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-314158|uniprotkb:Q23510|ensemblmetazoa:F54G8.4a.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:nhl1_caeel(display_long)|uniprotkb:nhl-1(gene name)|psi-mi:nhl-1(display_short)|uniprotkb:F54G8.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546955|imex:IM-18681-1073 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_499028.1|ensemblmetazoa:F54G8.4a.1(transcript)|ensemblmetazoa:WBGene00003597(gene)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030371"(translation repressor activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|wormbase:F54G8.4a|dip:DIP-26359N|uniprotkb:Q03601(identity)|wormbase:WBGene00003597(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:vg7P1U2gPP4ytoSs2LQ+HsIi60Q6239 intact-crc:61BAC5BE5E7D5532|rigid:7ya0YZ7WHqDJIRn2S57c62EVec4 false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76337 uniprotkb:G5EE56 intact:EBI-6532169|ensemblmetazoa:F56D2.7.1|uniprotkb:O01421 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:ced6_caeel(display_long)|uniprotkb:ced-6(gene name)|psi-mi:ced-6(display_short)|uniprotkb:Candidate adapter protein ced-6(gene name synonym)|uniprotkb:F56D2.7(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546970|imex:IM-18681-1074 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F56D2.7.1(transcript)|ensemblmetazoa:WBGene00000420(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0012501"(programmed cell death)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0070986"(left/right axis specification)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|go:"GO:1904747"(positive regulation of apoptotic process involved in development)|go:"GO:0045335"(phagocytic vesicle)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_498203.2|wormbase:F56D2.7|uniprotkb:O76337(identity)|wormbase:WBGene00000420(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 78|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:VjlyH911QZCg4QZbyWiJu1i01cg6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:BF5BC7065E7DCD62|rigid:VSVawg5Mw8B2k/E1nWXtvOkvICE false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01900 uniprotkb:G5EE56 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6546985|imex:IM-18681-1075 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N|uniprotkb:O01900(identity)|wormbase:WBGene00019124(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 48|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:8EB3E4FDBC3D7017|rigid:pmBBl5Zc2s0oPixs9H8Ee0ZivCY false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q8I4H7 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6536499|ensemblmetazoa:K02C4.5.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q8i4h7_caeel(display_long)|uniprotkb:CELE_K02C4.5(orf name)|uniprotkb:K02C4.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547000|imex:IM-18681-1076 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:K02C4.5.1(transcript)|ensemblmetazoa:WBGene00010503(gene)|refseq:NP_495695.2|wormbase:K02C4.5|uniprotkb:Q8I4H7(identity)|wormbase:WBGene00010503(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 59|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:/psCM8S6y04pL8WA8ShGIWUwm4Q6239 intact-crc:7B6CD38AF1BCBC77|rigid:WFsy2s7dODPwXJ0zaqf91eP//Ig false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q21648 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547015|imex:IM-18681-1077 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 51|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 intact-crc:7DDDB80E73222300|rigid:ZOD9fjSLlOUuvUOGT/NJQMr7dWg false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:F5GUF0 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6542338|ensemblmetazoa:R06C1.3b.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:f5guf0_caeel(display_long)|uniprotkb:R06C1.3(orf name)|uniprotkb:wve-1(gene name)|psi-mi:wve-1(display_short)|uniprotkb:CELE_R06C1.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547030|imex:IM-18681-1078 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:R06C1.3b.1(transcript)|ensemblmetazoa:WBGene00006958(gene)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031209"(SCAR complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|refseq:NP_001251762.1|wormbase:R06C1.3b|interpro:IPR028288|uniprotkb:F5GUF0(identity)|wormbase:WBGene00006958(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 11|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:Jmm0mWkD2Esf0E7aV7/qOpEnV906239 intact-crc:38AC07B2225AB2C0|rigid:MUVm/DvqVKpw440hV7TBOSxA50k false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:G5EC72 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6531450|ensemblmetazoa:T11B7.4a.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:g5ec72_caeel(display_long)|uniprotkb:T11B7.4(orf name)|uniprotkb:alp-1(gene name)|psi-mi:alp-1(display_short)|uniprotkb:CELE_T11B7.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547045|imex:IM-18681-1079 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) ensemblmetazoa:T11B7.4a.1(transcript)|ensemblmetazoa:WBGene00001132(gene)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0032432"(actin filament bundle)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0045177"(apical part of cell)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|refseq:NP_501533.2|wormbase:T11B7.4a|interpro:IPR036034|uniprotkb:G5EC72(identity)|wormbase:WBGene00001132(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 29|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:RiNxKPEqZzdZcK2XRkN4xV6ZfHk6239 intact-crc:2C4DDA1CB49CCEEF|rigid:n5o/LaiNfqAWzpbC/lYgF5veUTE false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QA6 uniprotkb:G5EE56 intact:EBI-327642|intact:EBI-11466567|intact:EBI-6531173|uniprotkb:H2KYY3|uniprotkb:H2KYY4|uniprotkb:H2KYY5|uniprotkb:H2KYY6|uniprotkb:H2KYY7|uniprotkb:H2KYY8|uniprotkb:H2KYY9|uniprotkb:H2KYZ0|uniprotkb:H2KYZ1|uniprotkb:H2KYZ2|uniprotkb:Q8MPW4|ensemblmetazoa:T17H7.4a.1|ensemblmetazoa:T17H7.4a.2 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:pat12_caeel(display_long)|uniprotkb:pat-12(gene name)|psi-mi:pat-12(display_short)|uniprotkb:Paralyzed arrest at two-fold 12 protein(gene name synonym)|uniprotkb:T17H7.4(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547060|imex:IM-18681-1080 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22534(uniprot-removed-ac)|refseq:NP_001022769.1|refseq:NP_497244.1|refseq:NP_497245.1|refseq:NP_497246.1|refseq:NP_497248.2|refseq:NP_741076.1|refseq:NP_741077.1|refseq:NP_741078.1|refseq:NP_741079.1|refseq:NP_741080.1|refseq:NP_741081.1|wormbase:T17H7.4a|wormbase:T17H7.4b|wormbase:T17H7.4c|wormbase:T17H7.4e|wormbase:T17H7.4f|wormbase:T17H7.4g|wormbase:T17H7.4h|wormbase:T17H7.4i|wormbase:T17H7.4j|wormbase:T17H7.4k|wormbase:T17H7.4l|refseq:NP_497247.2|wormbase:T17H7.4d|ensemblmetazoa:T17H7.4a.1(transcript)|ensemblmetazoa:T17H7.4a.2(transcript)|ensemblmetazoa:WBGene00003936(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0048598"(embryonic morphogenesis)|dip:DIP-27452N|uniprotkb:Q8MPW4(identity)|wormbase:WBGene00001573(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 37|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2016/07/12 rogid:DF4LwUE/fILZ5YaAJmMMxe5btQU6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:87B96C847ABC083E|rigid:IGcdn3X8W2+CU+oMUgDCNOdLWkw false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U304 uniprotkb:G5EE56 intact:EBI-329038|ensemblmetazoa:Y106G6D.7.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q9u304_caeel(display_long)|uniprotkb:rbm-12(gene name)|psi-mi:rbm-12(display_short)|uniprotkb:CELE_Y106G6D.7(orf name)|uniprotkb:Y106G6D.7(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547075|imex:IM-18681-1081 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492671.1|wormbase:Y106G6D.7|dip:DIP-26480N|ensemblmetazoa:WBGene00013703(gene)|ensemblmetazoa:Y106G6D.7.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|reactome:R-CEL-72163|uniprotkb:Q9U304(identity)|wormbase:WBGene00013703(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 28|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:/8MJkmHgCyjvgK0ZmDnklHVfJrw6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:136A44A81518F1DA|rigid:yfx5YOY8O06oopFVolri+oG8fc0 false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:G5EF87 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-311928|ensemblmetazoa:Y113G7B.23a.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:g5ef87_caeel(display_long)|uniprotkb:swsn-1(gene name)|psi-mi:swsn-1(display_short)|uniprotkb:psa-1(gene name synonym)|uniprotkb:Y113G7B.23(orf name)|uniprotkb:CELE_Y113G7B.23(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547090|imex:IM-18681-1082 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) uniprotkb:Q9U2W6(uniprot-removed-ac)|refseq:NP_001256906.1|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|ensemblmetazoa:WBGene00004203(gene)|ensemblmetazoa:Y113G7B.23a.1(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002119"(nematode larval development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR032448|interpro:IPR032451|wormbase:Y113G7B.23a|interpro:IPR036388|interpro:IPR038044|uniprotkb:G5EF87(identity)|wormbase:WBGene00004203(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:LXe8rVw0BSmSfyXr2pY+NPIHLTs6239 intact-crc:91FB0CDF6DCCD361|rigid:uSmAfgof7u0nsyG/cWgZ6bqqAmQ false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EGI2 uniprotkb:G5EE56 intact:EBI-6541649|ensemblmetazoa:Y38C1BA.2a.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:g5egi2_caeel(display_long)|uniprotkb:Y38C1BA.2(orf name)|uniprotkb:snn-1(gene name)|psi-mi:snn-1(display_short)|uniprotkb:syn(gene name synonym)|uniprotkb:CELE_Y38C1BA.2(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547105|imex:IM-18681-1083 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004913(gene)|ensemblmetazoa:Y38C1BA.2a.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0046872"(metal ion binding)|refseq:NP_741327.1|wormbase:Y38C1BA.2a|interpro:IPR001359(Synapsin)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR020897|interpro:IPR020898|uniprotkb:G5EGI2(identity)|wormbase:WBGene00004913(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:MH29+7Es7PNDOIE7j5XuTk9zSVY6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:8494EFCBF0CEC9AC|rigid:NieXUy5JXDBBIqDFj2YilZ7+/uw false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A8XMZ5 uniprotkb:G5EE56 intact:EBI-6547124|ensemblmetazoa:Y48B6A.6c.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:a8xmz5_caeel(display_long)|uniprotkb:CELE_Y48B6A.6(orf name)|uniprotkb:efhd-1(gene name)|psi-mi:efhd-1(display_short)|uniprotkb:Y48B6A.6(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547120|imex:IM-18681-1084 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00012980(gene)|ensemblmetazoa:Y48B6A.6c.1(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR040365|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001122657.1|wormbase:Y48B6A.6c|uniprotkb:A8XMZ5(identity)|wormbase:WBGene00012980(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:2KMUmFMYKRdhqfCfQuk1ucq5dPA6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:D851AC52A3F0114C|rigid:NP9SZocZUrZ1kT24h1/0IkXVFQ0 false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q9U290 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-6535173|ensemblmetazoa:Y48C3A.12.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q9u290_caeel(display_long)|uniprotkb:CELE_Y48C3A.12(orf name)|uniprotkb:Y48C3A.12(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547137|imex:IM-18681-1085 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) reactome:R-CEL-2672351|ensemblmetazoa:WBGene00012994(gene)|ensemblmetazoa:Y48C3A.12.1(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000580(TSC-22 / Dip / Bun)|refseq:NP_496820.3|wormbase:Y48C3A.12|uniprotkb:Q9U290(identity)|wormbase:WBGene00012994(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 67|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:j5mfkqYUtbsxlXm88eVGbYZKfe46239 intact-crc:5252B2E527DBB52E|rigid:HxWu33RiC23Hrzh9OwTz7LXiM/o false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:O18195 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-313368|ensemblmetazoa:Y48E1B.1.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:wash1_caeel(display_long)|uniprotkb:ddl-2(gene name)|psi-mi:ddl-2(display_short)|uniprotkb:Y48E1B.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547152|imex:IM-18681-1086 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) refseq:NP_496847.1|wormbase:Y48E1B.1|ensemblmetazoa:WBGene00013000(gene)|ensemblmetazoa:Y48E1B.1.1(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR021854|interpro:IPR028290|go:"GO:0043014"(alpha-tubulin binding)|dip:DIP-26697N|uniprotkb:O18195(identity)|wormbase:WBGene00013000(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 12|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:RJW5nUP6L8QcEdUDeGl4awDNlZU6239 intact-crc:6CFC4A7AAE4BD3BB|rigid:j8IZlEfJJqihYlQHfLbqK9oKZC8 false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A8XQ35 uniprotkb:G5EE56 intact:EBI-6542385|ensemblmetazoa:Y53H1A.1b.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:a8xq35_caeel(display_long)|uniprotkb:Y53H1A.1(orf name)|uniprotkb:rsy-1(gene name)|psi-mi:rsy-1(display_short)|uniprotkb:CELE_Y53H1A.1(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547167|imex:IM-18681-1087 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00013177(gene)|ensemblmetazoa:Y53H1A.1b.1(transcript)|go:"GO:0016607"(nuclear speck)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0005634"(nucleus)|interpro:IPR031937|refseq:NP_001122545.2|wormbase:Y53H1A.1b|uniprotkb:A8XQ35(identity)|wormbase:WBGene00013177(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|wormbase:WBGene00005077(identity)|uniprotkb:G5EE56(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 29|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:buN2kigAdUvAYZ2AhwHTaAMEjSo6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:D6347679B300F6CF|rigid:2BZkx50JrqBNIQFeEcwyIcaSSQU false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:G5ED33 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-2315916|ensemblmetazoa:Y57G11C.24g.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:g5ed33_caeel(display_long)|uniprotkb:eps-8(gene name)|psi-mi:eps-8(display_short)|uniprotkb:CELE_Y57G11C.24(orf name)|uniprotkb:Y57G11C.24(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547182|imex:IM-18681-1088 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) uniprotkb:Q6IZD5(uniprot-removed-ac)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_001041047.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039801|interpro:IPR033928|wormbase:Y57G11C.24g|mint:G5ED33|interpro:IPR035462|interpro:IPR036028|interpro:IPR041418|ensemblmetazoa:WBGene00001330(gene)|ensemblmetazoa:Y57G11C.24g.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030056"(hemidesmosome)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|uniprotkb:G5ED33(identity)|wormbase:WBGene00001330(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 93|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:GTD3+N5arMCOjaSLp0rs8FOsp0Y6239 intact-crc:466855CCEC2BA649|rigid:jeVmRprQM1Rn0b58By1ERKPzWbw false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U1W1 uniprotkb:G5EE56 intact:EBI-315106|ensemblmetazoa:Y63D3A.5.1|ensemblmetazoa:Y63D3A.5.2 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:tfg_caeel(display_long)|uniprotkb:tfg-1(gene name)|psi-mi:tfg-1(display_short)|uniprotkb:Y63D3A.5(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547197|imex:IM-18681-1089 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493462.1|wormbase:Y63D3A.5|ensemblmetazoa:WBGene00006565(gene)|ensemblmetazoa:Y63D3A.5.1(transcript)|ensemblmetazoa:Y63D3A.5.2(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009306"(protein secretion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072595"(maintenance of protein localization in organelle)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|dip:DIP-26017N|reactome:R-CEL-204005|uniprotkb:Q9U1W1(identity)|wormbase:WBGene00006565(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:nqyc7+EyDkiVah2+12hsLFWeNdA6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:297BC148E3F07B41|rigid:nJHYktdok1a1ebiB3ePoXszOlHY false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q4VNJ8 uniprotkb:G5EE56 intact:EBI-2918529 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q4vnj8_caeel(display_long)|uniprotkb:lin-65(gene name)|psi-mi:lin-65(display_short) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547212|imex:IM-18681-1090 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q4VNJ8(identity)|wormbase:WBGene00022149(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 7|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:RVORGWFAg9BFYQb458nv+PH8Ezk6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:90EB33540312BF16|rigid:u3e/pQyAZlYqgQqOnMK5TlemI9I false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NA61 uniprotkb:G5EE56 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547227|imex:IM-18681-1091 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 intact-crc:6566824428131952|rigid:Is9ib30+GOqI0gQCWaMW9XImqYQ false - sufficient binding region:74-131 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:G5EEQ3 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-319723|ensemblmetazoa:ZK1053.5.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:g5eeq3_caeel(display_long)|uniprotkb:scrm-2(gene name)|psi-mi:scrm-2(display_short)|uniprotkb:SCRM-2(gene name synonym)|uniprotkb:CELE_ZK1053.5(orf name)|uniprotkb:ZK1053.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547242|imex:IM-18681-1092 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) uniprotkb:O18289(uniprot-removed-ac)|ensemblmetazoa:WBGene00014200(gene)|ensemblmetazoa:ZK1053.5.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017128"(phospholipid scramblase activity)|interpro:IPR005552(Scramblase)|refseq:NP_493321.1|interpro:IPR025659|wormbase:ZK1053.5|uniprotkb:G5EEQ3(identity)|wormbase:WBGene00014200(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:ayiWZFoWx+GH3NI47lKkWqbGlYY6239 intact-crc:3BB936D3DBC3B94B|rigid:zBp8G/r50Ju63AMnfajD2hdqGvw false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE56 uniprotkb:Q9BIF4 intact:EBI-6538807|ensemblmetazoa:Y92H12A.1a.1|ensemblmetazoa:Y92H12A.1a.2|uniprotkb:W6RRW6|uniprotkb:W6RTE9|uniprotkb:W6SBD5 intact:EBI-11466207|ensemblmetazoa:ZK1248.3a.1 psi-mi:src1_caeel(display_long)|uniprotkb:src-1(gene name)|psi-mi:src-1(display_short)|uniprotkb:SRC oncogene related protein 1(gene name synonym)|uniprotkb:Y92H12A.1(orf name) psi-mi:q9bif4_caeel(display_long)|uniprotkb:ehs-1(gene name)|psi-mi:ehs-1(display_short)|uniprotkb:CELE_ZK1248.3(orf name)|uniprotkb:ZK1248.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547257|imex:IM-18681-1093 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|ensemblmetazoa:WBGene00005077(gene)|ensemblmetazoa:Y92H12A.1a.1(transcript)|ensemblmetazoa:Y92H12A.1a.2(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0001891"(phagocytic cup)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042995"(cell projection)|go:"GO:0043292"(contractile fiber)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:1990890"(netrin receptor binding)|wormbase:Y92H12A.1b|wormbase:Y92H12A.1c|wormbase:Y92H12A.1d|refseq:NP_001293420.1|refseq:NP_001293421.1|refseq:NP_001293422.1|reactome:R-CEL-1251985|reactome:R-CEL-1253288|reactome:R-CEL-1257604|reactome:R-CEL-1433557|reactome:R-CEL-186763|reactome:R-CEL-354192|reactome:R-CEL-354194|reactome:R-CEL-2454202|reactome:R-CEL-375165|reactome:R-CEL-3928662|reactome:R-CEL-3928663|reactome:R-CEL-3928664|reactome:R-CEL-3928665|reactome:R-CEL-399954|reactome:R-CEL-399955|reactome:R-CEL-399956|reactome:R-CEL-418592|reactome:R-CEL-418594|reactome:R-CEL-418885|reactome:R-CEL-430116|reactome:R-CEL-432142|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-456926|reactome:R-CEL-5621575|reactome:R-CEL-5663220|reactome:R-CEL-5673001|reactome:R-CEL-5674135|reactome:R-CEL-6811558|reactome:R-CEL-8874081|reactome:R-CEL-8934903|reactome:R-CEL-8941858|reactome:R-CEL-9009391|reactome:R-CEL-9013407|reactome:R-CEL-912631|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|refseq:NP_490866.4|wormbase:Y92H12A.1a|interpro:IPR036028|interpro:IPR036860|uniprotkb:G5EE56(identity)|wormbase:WBGene00005077(identity) interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_001022499.2|wormbase:ZK1248.3a|reactome:R-CEL-182971|reactome:R-CEL-6807004|ensemblmetazoa:WBGene00001224(gene)|ensemblmetazoa:ZK1248.3a.1(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016197"(endosomal transport)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030424"(axon)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|reactome:R-CEL-8856825|reactome:R-CEL-8856828|uniprotkb:D9N122(identity)|wormbase:WBGene00001224(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 39|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2018/02/09 rogid:KpXzUbTBNIwMpgVwov6Nkr8C/dg6239 rogid:y5IXfDhGVMZE5q1Fd1DhZY9xBX86239 intact-crc:B2013E0C33531669|rigid:+MF31Eef9+zZGGD0O9klCWfPBMc false sufficient binding region:74-131 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39055 uniprotkb:Q95PW9 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547272|imex:IM-18681-1094 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 14|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:27DD70920845C19C|rigid:Y0XRP+bSQ7zdGyYPlcQU4b9hGpI false - sufficient binding region:4-59 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:P34643 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-324902|uniprotkb:M1ZK05|ensemblmetazoa:ZK512.5a.1 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:sc161_caeel(display_long)|uniprotkb:sec-16A.1(gene name)|psi-mi:sec-16A.1(display_short)|uniprotkb:Secretory cargo traffic protein sec-16A.1(gene name synonym)|uniprotkb:sec-16(gene name synonym)|uniprotkb:ZK512.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547287|imex:IM-18681-1095 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) refseq:NP_499022.1|wormbase:ZK512.5a|wormbase:ZK512.5b|ensemblmetazoa:WBGene00013985(gene)|ensemblmetazoa:ZK512.5a.1(transcript)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|refseq:NP_001293651.1|dip:DIP-25929N|reactome:R-CEL-204005|uniprotkb:P34643(identity)|wormbase:WBGene00013985(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:MNubI0LLX2Ewt6rjY5w88MQajIo6239 intact-crc:504F8A615504D84B|rigid:uJJ0Oj2StSRvO/NWwdef4ETxCZ0 false sufficient binding region:4-59 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17744 uniprotkb:Q95PW9 intact:EBI-2315966|ensemblmetazoa:F43B10.1c.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:q17744_caeel(display_long)|uniprotkb:CELE_F43B10.1(orf name)|uniprotkb:F43B10.1(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547302|imex:IM-18681-1096 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011992(EF-Hand type)|interpro:IPR018247|wormbase:F43B10.1c|refseq:NP_001257277.1|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR041534|ensemblmetazoa:F43B10.1c.1(transcript)|ensemblmetazoa:WBGene00018373(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|uniprotkb:Q17744(identity)|wormbase:WBGene00015548(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 22|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:yBu4mQzQP54tuujYZMZhAIVmquE6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:10AF714601780834|rigid:dPaUAsYwhNeVWbXHKQgaGrDVbfc false - sufficient binding region:117-173 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17795 uniprotkb:Q95PW9 intact:EBI-2316131|ensemblmetazoa:C07G1.4a.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:q17795_caeel(display_long)|uniprotkb:wsp-1(gene name)|psi-mi:wsp-1(display_short)|uniprotkb:CELE_C07G1.4(orf name)|uniprotkb:C07G1.4(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547317|imex:IM-18681-1097 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741459.2|wormbase:C07G1.4a|interpro:IPR000697(EVH1)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR033927|interpro:IPR036936|interpro:IPR030214|ensemblmetazoa:C07G1.4a.1(transcript)|ensemblmetazoa:WBGene00006957(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|uniprotkb:Q17795(identity)|wormbase:WBGene00006957(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:YBTDOwM+8a5vUAiihYM6ezASlGY6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:8BEF990848ACBB4A|rigid:s42/VS05eV2fHUPVykSjuh0JXxE false - sufficient binding region:117-173 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17850 uniprotkb:Q95PW9 intact:EBI-327774|uniprotkb:Q22041|uniprotkb:Q86GT8|uniprotkb:Q86GT9|uniprotkb:Q86GU0|uniprotkb:Q94133|ensemblmetazoa:C09B8.7a.1|ensemblmetazoa:C09B8.7c.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:pk1_caeel(display_long)|uniprotkb:C09B8.7(orf name)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:CePAK(gene name synonym)|uniprotkb:pak-1(gene name)|psi-mi:pak-1(display_short) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547332|imex:IM-18681-1098 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024377.1|refseq:NP_001024378.1|refseq:NP_001024380.1|wormbase:C09B8.7a|wormbase:C09B8.7b|wormbase:C09B8.7c|wormbase:C09B8.7e|reactome:R-CEL-2029482|reactome:R-CEL-376172|reactome:R-CEL-3928662|reactome:R-CEL-389359|reactome:R-CEL-3928664|reactome:R-CEL-5218920|reactome:R-CEL-5621575|reactome:R-CEL-5627123|reactome:R-CEL-5687128|ensemblmetazoa:C09B8.7a.1(transcript)|ensemblmetazoa:C09B8.7c.1(transcript)|ensemblmetazoa:WBGene00003911(gene)|ensemblmetazoa:WBGene00003911(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040039"(inductive cell migration)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|dip:DIP-26715N|reactome:R-CEL-445144|reactome:R-CEL-8964616|refseq:NP_001024379.1|ensemblmetazoa:WBGene00003911(gene)|reactome:R-CEL-399954|reactome:R-CEL-4420097|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013406|reactome:R-CEL-9013407|reactome:R-CEL-9013420|reactome:R-CEL-9013424|uniprotkb:Q17850(identity)|wormbase:WBGene00003911(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:HpPsoVLC4dxbLGRUPS1ufsMjl1E6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:C57DE06385AA3A89|rigid:MMYAJgwhi7Lj9gtEnuJCxqjnGEc false - sufficient binding region:117-173 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:Q966J6 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-327612|ensemblmetazoa:F41B4.1.1 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:q966j6_caeel(display_long)|uniprotkb:F41B4.1(orf name)|uniprotkb:CELE_F41B4.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547347|imex:IM-18681-1099 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) refseq:NP_509148.2|wormbase:F41B4.1|ensemblmetazoa:F41B4.1.1(transcript)|ensemblmetazoa:WBGene00018257(gene)|dip:DIP-26336N|uniprotkb:Q966J6(identity)|wormbase:WBGene00018257(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:daBFAeewQ1vhaxj4tlw0watbWpw6239 intact-crc:C79C300DAD34BAEB|rigid:DjmSOcODtbeHVh5ZpALGqDbt9WM false sufficient binding region:117-173 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:O62332 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-317758|ensemblmetazoa:R06A4.4a.1 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:o62332_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:R06A4.4(orf name)|uniprotkb:CELE_R06A4.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547362|imex:IM-18681-1100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) refseq:NP_496987.1|wormbase:R06A4.4a|ensemblmetazoa:R06A4.4a.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|dip:DIP-25178N|uniprotkb:O62332(identity)|wormbase:WBGene00002076(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 9|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:vmad0aGDqxNwqAZYykq3lZt5zUs6239 intact-crc:FE60477ABA175FC0|rigid:fYTQGYER/3Si4aB85UqTXrn2R9g false sufficient binding region:117-173 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95PW9 uniprotkb:Q9XWN6 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 intact:EBI-325999|ensemblmetazoa:Y43F8C.14.1 psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:ani3_caeel(display_long)|uniprotkb:ani-3(gene name)|psi-mi:ani-3(display_short)|uniprotkb:Y43F8C.14(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547377|imex:IM-18681-1101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) refseq:NP_507814.1|wormbase:Y43F8C.14|ensemblmetazoa:WBGene00012835(gene)|ensemblmetazoa:Y43F8C.14.1(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0031106"(septin ring organization)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012966(Protein of unknown function DUF1709, fungi)|interpro:IPR037840|dip:DIP-26799N|uniprotkb:Q9XWN6(identity)|wormbase:WBGene00012835(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 rogid:6n+hwrX/jRh6Qbg0nXZ10omQxdM6239 intact-crc:6D6242541C73A053|rigid:iCNEvPm3LDbrZDsu0ix4aVGdF2o false sufficient binding region:117-173 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34258 uniprotkb:Q95PW9 intact:EBI-322705|ensemblmetazoa:B0303.7a.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:yka7_caeel(display_long)|uniprotkb:B0303.7(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547392|imex:IM-18681-1102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498918.3|wormbase:B0303.7a|interpro:IPR001452(Src homology-3)|ensemblmetazoa:B0303.7a.1(transcript)|ensemblmetazoa:WBGene00015128(gene)|interpro:IPR036028|uniprotkb:P34258(identity)|wormbase:WBGene00015128(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 102|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qEffDNcqvuiol+sUvczVQ/YB3ec6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:E462DFCE2487F48E|rigid:tT6aVdL97/tRCdK71tIFCeRE08A false - sufficient binding region:214-272 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09269 uniprotkb:Q95PW9 intact:EBI-6541936|ensemblmetazoa:C34C12.4.1|ensemblmetazoa:C34C12.4.2 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:yqf4_caeel(display_long)|uniprotkb:C34C12.4(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547407|imex:IM-18681-1103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C34C12.4.1(transcript)|ensemblmetazoa:C34C12.4.2(transcript)|ensemblmetazoa:WBGene00007923(gene)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR020309|refseq:NP_497715.2|wormbase:C34C12.4|uniprotkb:Q09269(identity)|wormbase:WBGene00007923(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:Vsx8Nori5LR5E0kGLRfYaWOfxQ06239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:02E87390FF919B72|rigid:qXvxj6DaFAHkE9jCGMD5SfPL0h4 false - sufficient binding region:214-272 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:H1UBJ9 uniprotkb:Q95PW9 intact:EBI-6547422|ensemblmetazoa:Y48C3A.14a.1 intact:EBI-6539663|ensemblmetazoa:ZK470.5a.1 psi-mi:h1ubj9_caeel(display_long)|uniprotkb:CELE_Y48C3A.14(orf name)|uniprotkb:Y48C3A.14(orf name) psi-mi:q95pw9_caeel(display_long)|uniprotkb:ZK470.5(orf name)|uniprotkb:nck-1(gene name)|psi-mi:nck-1(display_short)|uniprotkb:CELE_ZK470.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547424|imex:IM-18681-1104 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00012995(gene)|ensemblmetazoa:Y48C3A.14a.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR023405|interpro:IPR023406|refseq:NP_001254381.1|wormbase:Y48C3A.14a|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR034144|uniprotkb:H1UBJ9(identity)|wormbase:WBGene00012995(identity) ensemblmetazoa:WBGene00006410(gene)|ensemblmetazoa:ZK470.5a.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016301"(kinase activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|refseq:NP_508706.2|wormbase:ZK470.5a|interpro:IPR036028|interpro:IPR036860|uniprotkb:Q95PW9(identity)|wormbase:WBGene00006410(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:rjFDgDBwB9OCz1YMpyFOmDw8LKI6239 rogid:JzJUrYyk74W5PXJs9ZisZH5JoH86239 intact-crc:C95D16BCE9E39FE9|rigid:8QiopXiGKY9x/Tjv5sLgfdzjc+Q false - sufficient binding region:214-272 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91182 uniprotkb:Q9Y048 intact:EBI-2915585|ensemblmetazoa:C50F2.8.1 intact:EBI-322698|uniprotkb:Q9TZI6|ensemblmetazoa:F47G6.1a.1 psi-mi:p91182_caeel(display_long)|uniprotkb:magu-3(gene name)|psi-mi:magu-3(display_short)|uniprotkb:C50F2.8(orf name)|uniprotkb:CELE_C50F2.8(orf name) psi-mi:dtn1_caeel(display_long)|uniprotkb:F47G6.1(orf name)|uniprotkb:dyb-1(gene name)|psi-mi:dyb-1(display_short) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547439|imex:IM-18681-1105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C50F2.8.1(transcript)|ensemblmetazoa:WBGene00016841(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR027417|refseq:NP_491260.2|wormbase:C50F2.8|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR036028|interpro:IPR036034|uniprotkb:P91182(identity)|wormbase:WBGene00016841(identity) refseq:NP_490860.1|wormbase:F47G6.1|ensemblmetazoa:F47G6.1a.1(transcript)|ensemblmetazoa:WBGene00001115(gene)|go:"GO:0005277"(acetylcholine transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015870"(acetylcholine transport)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016014"(dystrobrevin complex)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0045202"(synapse)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|dip:DIP-25663N|uniprotkb:Q9Y048(identity)|wormbase:WBGene00001115(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:ZgolKbFquuYuk8AV1CgBpzt8+hg6239 rogid:k3D9uxI6JVwMQ4n/v0JtyOyEubg6239 intact-crc:F1F3DDF6CC585F18|rigid:9NP+G7jVOuEOKQ6hZWbKLlKi5Fg false sufficient binding region:211-275 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01796 uniprotkb:P91182 intact:EBI-318549|ensemblmetazoa:F53G12.4.1 intact:EBI-2915585|ensemblmetazoa:C50F2.8.1 psi-mi:o01796_caeel(display_long)|uniprotkb:F53G12.4(orf name)|uniprotkb:CELE_F53G12.4(orf name) psi-mi:p91182_caeel(display_long)|uniprotkb:magu-3(gene name)|psi-mi:magu-3(display_short)|uniprotkb:C50F2.8(orf name)|uniprotkb:CELE_C50F2.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547454|imex:IM-18681-1106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_490683.4|wormbase:F53G12.4|ensemblmetazoa:F53G12.4.1(transcript)|ensemblmetazoa:WBGene00018772(gene)|dip:DIP-26656N|uniprotkb:O01796(identity)|wormbase:WBGene00018772(identity) ensemblmetazoa:C50F2.8.1(transcript)|ensemblmetazoa:WBGene00016841(gene)|go:"GO:0016301"(kinase activity)|interpro:IPR027417|refseq:NP_491260.2|wormbase:C50F2.8|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR036028|interpro:IPR036034|uniprotkb:P91182(identity)|wormbase:WBGene00016841(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:8z7/f7MKp7d+Ui82s080b9wf0V86239 rogid:ZgolKbFquuYuk8AV1CgBpzt8+hg6239 intact-crc:6D512E6547ED4D8E|rigid:FQ05XtABqA/4vC1mRkX+VssmDmc false - sufficient binding region:211-275 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:O17099 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-2316398|ensemblmetazoa:F42G2.5.1 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:o17099_caeel(display_long)|uniprotkb:F42G2.5(orf name)|uniprotkb:CELE_F42G2.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547469|imex:IM-18681-1107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) refseq:NP_494271.1|wormbase:F42G2.5|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|ensemblmetazoa:F42G2.5.1(transcript)|ensemblmetazoa:WBGene00018354(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|uniprotkb:O17099(identity)|wormbase:WBGene00018354(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 25|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:daVhNCsoOEXdchv7tRHriHFYRlE6239 intact-crc:EDD7FB84233A5A1F|rigid:BbRjzLAghvOYMBtR9PE5QEm4Pp0 false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20498 uniprotkb:O18697 intact:EBI-2316401|uniprotkb:Q5WRQ3|ensemblmetazoa:F47A4.3a.1 intact:EBI-2414543|ensemblmetazoa:T04D3.1.1 psi-mi:rrc1_caeel(display_long)|uniprotkb:RhoGAP for Rac-1 and Cdc-42(gene name synonym)|uniprotkb:F47A4.3(orf name)|uniprotkb:rrc-1(gene name)|psi-mi:rrc-1(display_short) psi-mi:o18697_caeel(display_long)|uniprotkb:T04D3.1(orf name)|uniprotkb:CELE_T04D3.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547484|imex:IM-18681-1108 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024683.1|refseq:NP_001024684.1|wormbase:F47A4.3a|wormbase:F47A4.3b|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9035034|interpro:IPR036028|ensemblmetazoa:F47A4.3a.1(transcript)|ensemblmetazoa:WBGene00009800(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|uniprotkb:Q20498(identity)|wormbase:WBGene00009800(identity) refseq:NP_493340.1|wormbase:T04D3.1|interpro:IPR039908|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|ensemblmetazoa:T04D3.1.1(transcript)|ensemblmetazoa:WBGene00011431(gene)|uniprotkb:O18697(identity)|wormbase:WBGene00011431(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 28|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:DZDTz6cWzpCNIzbSqa5duaflv+A6239 rogid:lTFlKRwRy/hrr6MKu1xrh0JLUo86239 intact-crc:A18C48DBF95AB34E|rigid:hKi0p8dATVGDlu7VPDYWaEeIaIM false sufficient binding region:167-242 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4RZC8 uniprotkb:Q10457 intact:EBI-6540486|ensemblmetazoa:F56D12.4a.1 intact:EBI-311886|ensemblmetazoa:B0286.3.1 psi-mi:g4rzc8_caeel(display_long)|uniprotkb:F56D12.4(orf name)|uniprotkb:jip-1(gene name)|psi-mi:jip-1(display_short)|uniprotkb:CELE_F56D12.4(orf name) psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547499|imex:IM-18681-1109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F56D12.4a.1(transcript)|ensemblmetazoa:WBGene00002176(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0046328"(regulation of JNK cascade)|refseq:NP_001033330.1|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:F56D12.4a|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:G4RZC8(identity)|wormbase:WBGene00002176(identity) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 6|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/04/25 rogid:De9dyDC1TvB5bk1bsPDoJoF0XVk6239 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 intact-crc:BF84683C63DE32FE|rigid:K4yRimVbDyY1XwIIovaDdNlFAHY false sufficient binding region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4RZC8 uniprotkb:Q18192 intact:EBI-6540486|ensemblmetazoa:F56D12.4a.1 intact:EBI-319458|uniprotkb:Q5TYL7|uniprotkb:Q8MQB8|ensemblmetazoa:C26B2.3a.1|ensemblmetazoa:C26B2.3a.2 psi-mi:g4rzc8_caeel(display_long)|uniprotkb:F56D12.4(orf name)|uniprotkb:jip-1(gene name)|psi-mi:jip-1(display_short)|uniprotkb:CELE_F56D12.4(orf name) psi-mi:nhr31_caeel(display_long)|uniprotkb:nhr-31(gene name)|psi-mi:nhr-31(display_short)|uniprotkb:C26B2.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547514|imex:IM-18681-1110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F56D12.4a.1(transcript)|ensemblmetazoa:WBGene00002176(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0046328"(regulation of JNK cascade)|refseq:NP_001033330.1|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:F56D12.4a|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:G4RZC8(identity)|wormbase:WBGene00002176(identity) refseq:NP_001021330.1|refseq:NP_741456.1|wormbase:C26B2.3a|wormbase:C26B2.3c|ensemblmetazoa:C26B2.3a.1(transcript)|ensemblmetazoa:C26B2.3a.2(transcript)|ensemblmetazoa:WBGene00003625(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009886"(post-embryonic animal morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|go:"GO:0009792"(embryo development ending in birth or egg hatching)|dip:DIP-26995N|uniprotkb:Q18192(identity)|wormbase:WBGene00003625(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/04/25 rogid:De9dyDC1TvB5bk1bsPDoJoF0XVk6239 rogid:LkBZ9Hn9DwEQozpwaG7hIvHgVWk6239 intact-crc:58626CC17628558F|rigid:J04WF1eKPJXBqvEl+GmdOfGQhfk false sufficient binding region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDZ2 uniprotkb:G4RZC8 intact:EBI-313698|ensemblmetazoa:T07C4.1.1|ensemblmetazoa:T07C4.1.2 intact:EBI-6540486|ensemblmetazoa:F56D12.4a.1 psi-mi:umps_caeel(display_long)|uniprotkb:umps-1(gene name)|psi-mi:umps-1(display_short)|uniprotkb:rad-6(gene name synonym)|uniprotkb:T07C4.1(orf name) psi-mi:g4rzc8_caeel(display_long)|uniprotkb:F56D12.4(orf name)|uniprotkb:jip-1(gene name)|psi-mi:jip-1(display_short)|uniprotkb:CELE_F56D12.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547529|imex:IM-18681-1111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q18516(uniprot-removed-ac)|interpro:IPR001754(Orotidine 5'-phosphate decarboxylase, core)|interpro:IPR004467(Orotate phosphoribosyl transferase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR014732(Orotidine 5'-phosphate decarboxylase, subfamily 1, core)|interpro:IPR023031|refseq:NP_499291.1|mint:G5EDZ2|wormbase:T07C4.1|ensemblmetazoa:T07C4.1.1(transcript)|ensemblmetazoa:T07C4.1.2(transcript)|ensemblmetazoa:WBGene00011559(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0004588"(orotate phosphoribosyltransferase activity)|go:"GO:0004590"(orotidine-5'-phosphate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006222"(UMP biosynthetic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009411"(response to UV)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0090727"(positive regulation of brood size)|reactome:R-CEL-500753|interpro:IPR029057|interpro:IPR000836(Phosphoribosyltransferase)|uniprotkb:G5EDZ2(identity)|wormbase:WBGene00011559(identity) ensemblmetazoa:F56D12.4a.1(transcript)|ensemblmetazoa:WBGene00002176(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0046328"(regulation of JNK cascade)|refseq:NP_001033330.1|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:F56D12.4a|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:G4RZC8(identity)|wormbase:WBGene00002176(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/04/25 rogid:Cpk0wa1uimBSN+c829/7jJMJdLk6239 rogid:De9dyDC1TvB5bk1bsPDoJoF0XVk6239 intact-crc:0610290665F8D0BB|rigid:lg9Z68rqEyjiRE1V/jr84VShSik false - sufficient binding region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:H2KZZ2 uniprotkb:G4RZC8 intact:EBI-2420815|intact:EBI-6765823|intact:EBI-6541491|uniprotkb:A0A2X0RWL7|uniprotkb:A0A2X0T4B7|uniprotkb:H2KZZ0|uniprotkb:H2KZZ1|uniprotkb:H2KZZ3|uniprotkb:H2KZZ4|uniprotkb:Q5TYL0|uniprotkb:Q86MJ3|uniprotkb:Q86MJ4|ensemblmetazoa:W02C12.3c.1 intact:EBI-6540486|ensemblmetazoa:F56D12.4a.1 psi-mi:hlh30_caeel(display_long)|uniprotkb:hlh-30(gene name)|psi-mi:hlh-30(display_short)|uniprotkb:W02C12.3(orf name) psi-mi:g4rzc8_caeel(display_long)|uniprotkb:F56D12.4(orf name)|uniprotkb:jip-1(gene name)|psi-mi:jip-1(display_short)|uniprotkb:CELE_F56D12.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547544|imex:IM-18681-1112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q95ZK5(uniprot-removed-ac)|reactome:R-CEL-3232118|refseq:NP_001023411.1|wormbase:W02C12.3a|wormbase:W02C12.3c|wormbase:W02C12.3d|wormbase:W02C12.3e|wormbase:W02C12.3f|wormbase:W02C12.3g|wormbase:W02C12.3h|wormbase:W02C12.3i|wormbase:W02C12.3j|interpro:IPR011598(Helix-loop-helix DNA-binding)|wormbase:W02C12.3b|interpro:IPR036638|refseq:NP_001023412.1|refseq:NP_001023413.1|refseq:NP_001023414.1|refseq:NP_001023415.1|refseq:NP_001023416.1|refseq:NP_500461.1|refseq:NP_500462.1|ensemblmetazoa:W02C12.3c.1(transcript)|ensemblmetazoa:WBGene00020930(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:1905686"(positive regulation of plasma membrane repair)|uniprotkb:Q5TYL0(identity)|wormbase:WBGene00020930(identity) ensemblmetazoa:F56D12.4a.1(transcript)|ensemblmetazoa:WBGene00002176(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0046328"(regulation of JNK cascade)|refseq:NP_001033330.1|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:F56D12.4a|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:G4RZC8(identity)|wormbase:WBGene00002176(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2021/02/11 rogid:iGZh0KT07VIYofGovWOZj0raCt06239 rogid:De9dyDC1TvB5bk1bsPDoJoF0XVk6239 intact-crc:6F7DF3B895DAC8BE|rigid:D+7CfQd1xXlZdYz3t1+l7vffEGc false - sufficient binding region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4RZC8 uniprotkb:Q9NA61 intact:EBI-6540486|ensemblmetazoa:F56D12.4a.1 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 psi-mi:g4rzc8_caeel(display_long)|uniprotkb:F56D12.4(orf name)|uniprotkb:jip-1(gene name)|psi-mi:jip-1(display_short)|uniprotkb:CELE_F56D12.4(orf name) psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547559|imex:IM-18681-1113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F56D12.4a.1(transcript)|ensemblmetazoa:WBGene00002176(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0046328"(regulation of JNK cascade)|refseq:NP_001033330.1|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:F56D12.4a|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:G4RZC8(identity)|wormbase:WBGene00002176(identity) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2020/04/25 rogid:De9dyDC1TvB5bk1bsPDoJoF0XVk6239 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 intact-crc:22C1134304B6FEF0|rigid:+G8ho3uhgBLq3RYd/VQpVnYV8r4 false sufficient binding region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4RZC8 uniprotkb:A0A5E4M3Q4 intact:EBI-6540486|ensemblmetazoa:F56D12.4a.1 intact:EBI-329613|ensemblmetazoa:ZK867.1b.1|ensemblmetazoa:ZK867.1b.2|ensemblmetazoa:ZK867.1c.1|ensemblmetazoa:ZK867.1d.1|intact:EBI-6547578|intact:EBI-2421085|uniprotkb:A0A5E4LWX4|uniprotkb:Q95PV3|uniprotkb:Q95PV5|uniprotkb:Q95PV6 psi-mi:g4rzc8_caeel(display_long)|uniprotkb:F56D12.4(orf name)|uniprotkb:jip-1(gene name)|psi-mi:jip-1(display_short)|uniprotkb:CELE_F56D12.4(orf name) psi-mi:syd9_caeel(display_long)|uniprotkb:syd-9(gene name)|psi-mi:syd-9(display_short)|uniprotkb:Synapse defective protein 9(gene name synonym)|uniprotkb:tag-239(gene name synonym)|uniprotkb:ztf-10(gene name synonym)|uniprotkb:ZK867.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547574|imex:IM-18681-1114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F56D12.4a.1(transcript)|ensemblmetazoa:WBGene00002176(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0046328"(regulation of JNK cascade)|refseq:NP_001033330.1|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|wormbase:F56D12.4a|interpro:IPR001452(Src homology-3)|interpro:IPR036028|uniprotkb:G4RZC8(identity)|wormbase:WBGene00002176(identity) refseq:NP_509213.1|wormbase:ZK867.1d|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensemblmetazoa:WBGene00044068(gene)|ensemblmetazoa:ZK867.1b.1(transcript)|ensemblmetazoa:ZK867.1b.2(transcript)|ensemblmetazoa:ZK867.1c.1(transcript)|ensemblmetazoa:ZK867.1d.1(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_509214.2|refseq:NP_509216.1|wormbase:ZK867.1b|wormbase:ZK867.1c|wormbase:ZK867.1e|wormbase:ZK867.1f|uniprotkb:Q95PV3(identity)|wormbase:WBGene00044068(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2021/11/29 rogid:De9dyDC1TvB5bk1bsPDoJoF0XVk6239 rogid:nzwv2m2v5wE78ifcBu8+ncf3zpk6239 intact-crc:C75BFEA6716ECBB3|rigid:pmll3Sz60n3L/NJ4UgVVfYLz+Zk false sufficient binding region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:B4E3X6 intact:EBI-6540576 intact:EBI-6547595|ensemblmetazoa:Y46G5A.19b.1|ensemblmetazoa:Y46G5A.19b.2 - psi-mi:b4e3x6_caeel(display_long)|uniprotkb:CELE_Y46G5A.19(orf name)|uniprotkb:spds-1(gene name)|psi-mi:spds-1(display_short)|uniprotkb:Y46G5A.19(orf name) psi-mi:g5ecg5_caeel(display_short)|psi-mi:EBI-6540576(display_long)|uniprotkb:ZK1151.1(orf name)|uniprotkb:vab-10(gene name)|psi-mi:vab-10(display_short)|uniprotkb:CELE_ZK1151.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547591|imex:IM-18681-1115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00012909(gene)|ensemblmetazoa:Y46G5A.19b.1(transcript)|ensemblmetazoa:Y46G5A.19b.2(transcript)|go:"GO:0004766"(spermidine synthase activity)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008295"(spermidine biosynthetic process)|interpro:IPR030373|interpro:IPR030374|interpro:IPR001045(Spermine synthase)|refseq:NP_001129829.1|wormbase:Y46G5A.19b|reactome:R-CEL-351202|interpro:IPR029063|interpro:IPR035246|interpro:IPR030668|interpro:IPR037163|uniprotkb:B4E3X6(identity)|wormbase:WBGene00012909(identity) uniprotkb:G5ECG5(uniprot-removed-ac)|uniprotkb:G5ECG5(identity)|wormbase:WBGene00006876(identity) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Supplementary table 3|comment:Y2H colony count - 13|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:2OTQC7ynUn1ioSamzfNK1nN93+E6239 rogid:riVHU5Xpw7K9oQCE4DIP2G0Yoes6239 intact-crc:B4BDFD1A8458352A|rigid:TCYoeDVJN+gQUv6x4essAJmsgJ8 false - sufficient binding region:820-873 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q10457 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-311886|ensemblmetazoa:B0286.3.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:pur6_caeel(display_long)|uniprotkb:pacs-1(gene name)|psi-mi:pacs-1(display_short)|uniprotkb:B0286.3(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547608|imex:IM-18681-1116 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_494771.1|wormbase:B0286.3|ensemblmetazoa:B0286.3.1(transcript)|ensemblmetazoa:WBGene00015116(gene)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|reactome:R-CEL-73817|dip:DIP-24510N|uniprotkb:Q10457(identity)|wormbase:WBGene00015116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:eV1Nxe+7Kdror1S6YrP9aSvgh+Y6239 intact-crc:936ADA6A031E5F2F|rigid:RzuPwbaamrXHiKTbVgriByvuMZI false sufficient binding region:252-309 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39055 uniprotkb:G5ECK4 intact:EBI-317945|uniprotkb:Q93176|uniprotkb:Q95QY9|ensemblmetazoa:C02C6.1a.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:dyn1_caeel(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547623|imex:IM-18681-1117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-437239|reactome:R-CEL-8856828|interpro:IPR030381|refseq:NP_001024331.1|refseq:NP_001024332.1|wormbase:C02C6.1a|wormbase:C02C6.1b|interpro:IPR022812|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR019762|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR020850|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027417|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031143"(pseudopodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0090386"(phagosome maturation involved in apoptotic cell clearance)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:1990075"(periciliary membrane compartment)|go:"GO:0031966"(mitochondrial membrane)|reactome:R-CEL-1169408|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|interpro:IPR027741|reactome:R-CEL-190873|reactome:R-CEL-196025|uniprotkb:P39055(identity)|wormbase:WBGene00001130(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 25|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:B15DE6C30016E15B|rigid:1osvjpZSpAVuMsvcfbirh6m9Trk false - sufficient binding region:252-309 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:O61980 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-317983|ensemblmetazoa:H14N18.1a.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:o61980_caeel(display_long)|uniprotkb:unc-23(gene name)|psi-mi:unc-23(display_short)|uniprotkb:H14N18.1(orf name)|uniprotkb:CELE_H14N18.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547638|imex:IM-18681-1118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_505307.1|wormbase:H14N18.1a|ensemblmetazoa:H14N18.1a.1(transcript)|ensemblmetazoa:WBGene00006760(gene)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016203"(muscle attachment)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031430"(M band)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0055120"(striated muscle dense body)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|dip:DIP-27172N|reactome:R-CEL-3371453|uniprotkb:O61980(identity)|wormbase:WBGene00006760(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:wpIP/eJ9LY4G0prjS57qO9ZWCr86239 intact-crc:67186FC7BD61FDB8|rigid:BnO4ZARQ+ug6JgZIkILSSSorwo4 false sufficient binding region:252-309 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q9NA61 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-6541512|ensemblmetazoa:Y73F8A.8.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q9na61_caeel(display_long)|uniprotkb:Y73F8A.8(orf name)|uniprotkb:pqn-90(gene name)|psi-mi:pqn-90(display_short)|uniprotkb:CELE_Y73F8A.8(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547653|imex:IM-18681-1119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) ensemblmetazoa:WBGene00004170(gene)|ensemblmetazoa:Y73F8A.8.1(transcript)|refseq:NP_502843.1|wormbase:Y73F8A.8|uniprotkb:Q9NA61(identity)|wormbase:WBGene00004170(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:WYgLD+l00HlC+6SgJQSb5udZdyo6239 intact-crc:4FD2E290B97F6B58|rigid:VBzZjHKRQGhS02J0uVIDyYhKKo0 false sufficient binding region:252-309 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q17744 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-2315966|ensemblmetazoa:F43B10.1c.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q17744_caeel(display_long)|uniprotkb:CELE_F43B10.1(orf name)|uniprotkb:F43B10.1(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547668|imex:IM-18681-1120 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) interpro:IPR011992(EF-Hand type)|interpro:IPR018247|wormbase:F43B10.1c|refseq:NP_001257277.1|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR041534|ensemblmetazoa:F43B10.1c.1(transcript)|ensemblmetazoa:WBGene00018373(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|uniprotkb:Q17744(identity)|wormbase:WBGene00015548(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:yBu4mQzQP54tuujYZMZhAIVmquE6239 intact-crc:99F5823B1A44D048|rigid:sO3IxNmp++Ry9iq7pwuAuY8un7M false sufficient binding region:1464-1523 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17795 uniprotkb:G5ECK4 intact:EBI-2316131|ensemblmetazoa:C07G1.4a.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:q17795_caeel(display_long)|uniprotkb:wsp-1(gene name)|psi-mi:wsp-1(display_short)|uniprotkb:CELE_C07G1.4(orf name)|uniprotkb:C07G1.4(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547683|imex:IM-18681-1121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741459.2|wormbase:C07G1.4a|interpro:IPR000697(EVH1)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR033927|interpro:IPR036936|interpro:IPR030214|ensemblmetazoa:C07G1.4a.1(transcript)|ensemblmetazoa:WBGene00006957(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|uniprotkb:Q17795(identity)|wormbase:WBGene00006957(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 3|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:YBTDOwM+8a5vUAiihYM6ezASlGY6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:EEB7F7F30E46DF1A|rigid:8tmyQI1+rq6rMRXzU5IgDfQWcwE false - sufficient binding region:1464-1523 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6544261 uniprotkb:G5ECK4 - intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:e2iub2_caeel(display_short)|psi-mi:EBI-6544261(display_long)|uniprotkb:egl-9.4c(gene name)|psi-mi:egl-9.4c(display_short) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547698|imex:IM-18681-1122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:E2IUB2(uniprot-removed-ac)|uniprotkb:E2IUB2(identity)|wormbase:WBGene00001178(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Supplementary table 3|comment:Y2H colony count - 10|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:vfYsuFRpiksvZtgFcOhSp7YRmy06239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:3EE1286AB2298320|rigid:18/IqrreWjVqbjPs2EeGW3aghDA false - sufficient binding region:1464-1523 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09345 uniprotkb:G5ECK4 intact:EBI-2006279|ensemblmetazoa:R144.2a.1|ensemblmetazoa:R144.2a.2 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:pcf11_caeel(display_long)|uniprotkb:R144.2(orf name)|uniprotkb:pcf-11(gene name)|psi-mi:pcf-11(display_short) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547713|imex:IM-18681-1123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498068.1|wormbase:R144.2a|interpro:IPR008942(ENTH/VHS)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|reactome:R-CEL-6807505|reactome:R-CEL-73856|ensemblmetazoa:R144.2a.1(transcript)|ensemblmetazoa:R144.2a.2(transcript)|ensemblmetazoa:WBGene00020092(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|uniprotkb:Q09345(identity)|wormbase:WBGene00020092(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 4|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:XTyRR+k9dN5uoxwUXnAuM34SSUA6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:439205E84F7B7D07|rigid:VX3GGXyZdfeUv4GK/pErS1hS9js false - sufficient binding region:1464-1523 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XTY6 uniprotkb:G5ECK4 intact:EBI-495781|uniprotkb:Q9BKB5|uniprotkb:Q9XTY4|ensemblmetazoa:T03D8.1a.1 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 psi-mi:numb1_caeel(display_long)|uniprotkb:Protein kinase C adapter 1(gene name synonym)|uniprotkb:CKA1(gene name synonym)|uniprotkb:num-1(gene name)|psi-mi:num-1(display_short)|uniprotkb:cka-1(gene name synonym)|uniprotkb:T03D8.1(orf name) psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547728|imex:IM-18681-1124 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001024097.1|refseq:NP_001024098.1|refseq:NP_508021.1|wormbase:T03D8.1a|wormbase:T03D8.1b|wormbase:T03D8.1c|interpro:IPR016698(Numb/numb-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|reactome:R-CEL-437239|reactome:R-CEL-5610780|reactome:R-CEL-5632684|ensemblmetazoa:T03D8.1a.1(transcript)|ensemblmetazoa:WBGene00003830(gene)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0051117"(ATPase binding)|uniprotkb:Q9XTY6(identity)|wormbase:WBGene00003830(identity) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 32|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:qO+DFvMBt2DE+ZS7l8axk5DMOFQ6239 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 intact-crc:F1A164A54C9A3361|rigid:MVLUBRkYaZBHKjmUB54YiyOodJs false - sufficient binding region:1464-1523 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q95Y26 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-2316437|ensemblmetazoa:Y41D4A.5.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q95y26_caeel(display_long)|uniprotkb:ptpn-22(gene name)|psi-mi:ptpn-22(display_short)|uniprotkb:CELE_Y41D4A.5(orf name)|uniprotkb:Y41D4A.5(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547743|imex:IM-18681-1125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_500128.2|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|wormbase:Y41D4A.5|interpro:IPR029021|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|reactome:R-CEL-388844|ensemblmetazoa:WBGene00021507(gene)|ensemblmetazoa:Y41D4A.5.1(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008045"(motor neuron axon guidance)|uniprotkb:Q95Y26(identity)|wormbase:WBGene00021507(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 8|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:sXWy7Nr8zlq7TXysWGI7SNNBjeM6239 intact-crc:3EC1EC9F1C14FE08|rigid:FdBQCzKMMrgZZFh36ferxncQj1E false sufficient binding region:1464-1523 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECK4 uniprotkb:Q95XW7 intact:EBI-6533538|ensemblmetazoa:Y37A1B.17a.1 intact:EBI-2316700|ensemblmetazoa:Y55B1BR.2.1 psi-mi:g5eck4_caeel(display_long)|uniprotkb:CELE_Y37A1B.17(orf name)|uniprotkb:Y37A1B.17(orf name) psi-mi:q95xw7_caeel(display_long)|uniprotkb:affl-2(gene name)|psi-mi:affl-2(display_short)|uniprotkb:CELE_Y55B1BR.2(orf name)|uniprotkb:Y55B1BR.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547758|imex:IM-18681-1126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027267|ensemblmetazoa:WBGene00044989(gene)|ensemblmetazoa:Y37A1B.17a.1(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|reactome:R-CEL-9013148|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|refseq:NP_001076722.2|wormbase:Y37A1B.17a|reactome:R-CEL-193648|interpro:IPR035899|interpro:IPR036028|reactome:R-CEL-416482|uniprotkb:G5ECK4(identity)|wormbase:WBGene00044989(identity) refseq:NP_497199.1|wormbase:Y55B1BR.2|interpro:IPR043640|ensemblmetazoa:WBGene00021912(gene)|ensemblmetazoa:Y55B1BR.2.1(transcript)|go:"GO:0005634"(nucleus)|uniprotkb:Q95XW7(identity)|wormbase:WBGene00021912(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - Yes"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:LucS+t3WflYXNHm3sQvF79WKphs6239 rogid:JxmHFANXh2vyB+sppuHlgubtfW86239 intact-crc:707CACAE23553B96|rigid:hKlT0Whq6tzHgHZjtkZXHnm8Jz4 false sufficient binding region:1464-1523 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A5JYT2 uniprotkb:Q6A573 intact:EBI-2915506|ensemblmetazoa:C01H6.7b.1|ensemblmetazoa:C01H6.7b.2 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:a5jyt2_caeel(display_long)|uniprotkb:swsn-9(gene name)|psi-mi:swsn-9(display_short)|uniprotkb:C01H6.7(orf name)|uniprotkb:CELE_C01H6.7(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547773|imex:IM-18681-1127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C01H6.7b.1(transcript)|ensemblmetazoa:C01H6.7b.2(transcript)|ensemblmetazoa:WBGene00007256(gene)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR021900|refseq:NP_001122414.1|wormbase:C01H6.7b|interpro:IPR036427|uniprotkb:A5JYT2(identity)|wormbase:WBGene00007256(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 213|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:NIbg+K7XjZYxaPiVFKQReT8j6vE6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:E3DCB27DDCBD3ED3|rigid:CuY79Vxz0p+HeLeE1u4M+BvhM1U false - sufficient binding region:49-106 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21648 uniprotkb:Q6A573 intact:EBI-314179|ensemblmetazoa:R02F2.5.1 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:q21648_caeel(display_long)|uniprotkb:R02F2.5(orf name)|uniprotkb:CELE_R02F2.5(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547788|imex:IM-18681-1128 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498169.1|wormbase:R02F2.5|ensemblmetazoa:R02F2.5.1(transcript)|ensemblmetazoa:WBGene00019834(gene)|dip:DIP-25723N|uniprotkb:Q21648(identity)|wormbase:WBGene00019834(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 5|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:4sj3ml+jXILOveJBxch1enEqcKY6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:BBDDADF749F6A470|rigid:AcDHAkOtQsdTebd4U2nrBtGZpSY false - sufficient binding region:49-106 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E8MDW3 uniprotkb:Q6A573 intact:EBI-6547803|ensemblmetazoa:Y105E8A.21b.1 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 psi-mi:e8mdw3_caeel(display_long)|uniprotkb:CELE_Y105E8A.21(orf name)|uniprotkb:Y105E8A.21(orf name) psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547805|imex:IM-18681-1129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00013679(gene)|ensemblmetazoa:Y105E8A.21b.1(transcript)|refseq:NP_001252372.1|wormbase:Y105E8A.21b|uniprotkb:E8MDW3(identity)|wormbase:WBGene00013679(identity) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 2|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:2jh6asHV9lA5yDAWXhbJ3Jv5u+Q6239 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 intact-crc:98FEA791B4EC00BB|rigid:nd/GukubYTqq2zE6iDBA5FSf7Js false - sufficient binding region:49-106 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6A573 uniprotkb:Q94418 intact:EBI-6532308|ensemblmetazoa:Y44E3A.4.1 intact:EBI-593113|ensemblmetazoa:ZK858.2.1 psi-mi:q6a573_caeel(display_long)|uniprotkb:cdap-2(gene name)|psi-mi:cdap-2(display_short)|uniprotkb:CELE_Y44E3A.4(orf name)|uniprotkb:Y44E3A.4(orf name) psi-mi:q94418_caeel(display_long)|uniprotkb:CELE_ZK858.2(orf name)|uniprotkb:ZK858.2(orf name) psi-mi:"MI:0018"(two hybrid) Xin et al. (2013) imex:IM-18681|pubmed:23549480 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6547820|imex:IM-18681-1130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00021549(gene)|ensemblmetazoa:Y44E3A.4.1(transcript)|interpro:IPR001452(Src homology-3)|wormbase:Y44E3A.4|refseq:NP_491143.3|interpro:IPR036028|uniprotkb:Q6A573(identity)|wormbase:WBGene00021549(identity) refseq:NP_492447.1|wormbase:ZK858.2|ensemblmetazoa:WBGene00014116(gene)|ensemblmetazoa:ZK858.2.1(transcript)|uniprotkb:Q94418(identity)|wormbase:WBGene00014116(identity) - - - figure legend:Supplementary table 3|comment:Y2H colony count - 1|comment:"Confirmed by pairwise retest in PMID:19447967 - No"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/02/20 2014/10/16 rogid:W//hvaMk+bH2N6g7E/P25oqKclE6239 rogid:Hd/z2Kak3QHyR3gRPGcH61lG9Ho6239 intact-crc:BB72F891E31A6264|rigid:DP0kVoDRAmHAwurbLKzVNfqOs6g false sufficient binding region:49-106 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)