#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P95493 uniprotkb:P15516 intact:EBI-8505881|intact:MINT-8415911|uniprotkb:O33441|ensemblbacteria:AAQ65700 intact:EBI-738783|uniprotkb:Q16243|uniprotkb:Q502Z1|ensembl:ENSP00000432561|ensembl:ENSP00000489520|ensembl:ENSP00000500623|ensembl:ENSP00000500810|ensembl:ENSP00000504141 psi-mi:cpg2_porgi(display_long)|uniprotkb:rgpB(gene name)|psi-mi:rgpB(display_short)|uniprotkb:Arg-gingipain(gene name synonym)|uniprotkb:Gingipain 2(gene name synonym)|uniprotkb:RGP-2(gene name synonym)|uniprotkb:prtRII(gene name synonym)|uniprotkb:rgp2(gene name synonym)|uniprotkb:PG_0506(locus name) psi-mi:his3_human(display_long)|uniprotkb:HTN3(gene name)|psi-mi:HTN3(display_short)|uniprotkb:HIS2(gene name synonym)|uniprotkb:Histidine-rich protein 3(gene name synonym)|uniprotkb:PB(gene name synonym)|uniprotkb:Basic histidine-rich protein(gene name synonym) psi-mi:"MI:0435"(protease assay) Chen et al. (2013) mint:MINT-8415905|mint:d-12-02105r1|pubmed:23499434 taxid:242619(porgi)|taxid:242619("Porphyromonas gingivalis (strain ATCC BAA-308 / W83)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8505906|mint:MINT-8415924 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026444|interpro:IPR012600(Propetide, peptidase C25)|interpro:IPR001769(Peptidase C25, gingipain)|interpro:IPR005536(Peptidase C25, C-terminal Ig-like region)|interpro:IPR014756(Immunoglobulin E-set)|refseq:WP_010956050.1|interpro:IPR039392|interpro:IPR029030|interpro:IPR029031|mint:P95493|interpro:IPR038490|interpro:IPR041333|ensemblbacteria:AAQ65700(transcript)|ensemblbacteria:PG_0506(gene)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|rcsb pdb:1CVR|rcsb pdb:4IEF|rcsb pdb:5AG8|rcsb pdb:5AG9|rcsb pdb:5HFS|mint:MINT-8415926(identity) ensembl:ENST00000673563(transcript)|ensembl:ENST00000677679(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR030773|interpro:IPR030774|mint:P15516|reactome:R-HSA-6803157|go:"GO:0046872"(metal ion binding)|refseq:NP_000191.1|ensembl:ENSG00000205649(gene)|ensembl:ENSG00000282967(gene)|ensembl:ENST00000530128(transcript)|ensembl:ENST00000635585(transcript)|ensembl:ENST00000672568(transcript)|mint:MINT-8415928(identity) - comment:mint - comment:mint|figure legend:f3 f4 t1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/01 2014/10/16 rogid:rMxS3uspMyQcE6zyqk11Bi01ALY242619 rogid:CEDvaZZ2Azjwy1B6E+ZyYd+UISA9606 intact-crc:F80DA4BFC70C62DB|rigid:JwGdfPA/UoKW3okKhPAgFgIoVGw false - uncategorized protein modification:25-25(MINT-8415939) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P95493 uniprotkb:P15516 intact:EBI-8505881|intact:MINT-8415911|uniprotkb:O33441|ensemblbacteria:AAQ65700 intact:EBI-738783|uniprotkb:Q16243|uniprotkb:Q502Z1|ensembl:ENSP00000432561|ensembl:ENSP00000489520|ensembl:ENSP00000500623|ensembl:ENSP00000500810|ensembl:ENSP00000504141 psi-mi:cpg2_porgi(display_long)|uniprotkb:rgpB(gene name)|psi-mi:rgpB(display_short)|uniprotkb:Arg-gingipain(gene name synonym)|uniprotkb:Gingipain 2(gene name synonym)|uniprotkb:RGP-2(gene name synonym)|uniprotkb:prtRII(gene name synonym)|uniprotkb:rgp2(gene name synonym)|uniprotkb:PG_0506(locus name) psi-mi:his3_human(display_long)|uniprotkb:HTN3(gene name)|psi-mi:HTN3(display_short)|uniprotkb:HIS2(gene name synonym)|uniprotkb:Histidine-rich protein 3(gene name synonym)|uniprotkb:PB(gene name synonym)|uniprotkb:Basic histidine-rich protein(gene name synonym) psi-mi:"MI:0435"(protease assay) Chen et al. (2013) mint:MINT-8415905|mint:d-12-02105r1|pubmed:23499434 taxid:242619(porgi)|taxid:242619("Porphyromonas gingivalis (strain ATCC BAA-308 / W83)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8505938|mint:MINT-8415952 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026444|interpro:IPR012600(Propetide, peptidase C25)|interpro:IPR001769(Peptidase C25, gingipain)|interpro:IPR005536(Peptidase C25, C-terminal Ig-like region)|interpro:IPR014756(Immunoglobulin E-set)|refseq:WP_010956050.1|interpro:IPR039392|interpro:IPR029030|interpro:IPR029031|mint:P95493|interpro:IPR038490|interpro:IPR041333|ensemblbacteria:AAQ65700(transcript)|ensemblbacteria:PG_0506(gene)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|rcsb pdb:1CVR|rcsb pdb:4IEF|rcsb pdb:5AG8|rcsb pdb:5AG9|rcsb pdb:5HFS|mint:MINT-8415954(identity) ensembl:ENST00000673563(transcript)|ensembl:ENST00000677679(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR030773|interpro:IPR030774|mint:P15516|reactome:R-HSA-6803157|go:"GO:0046872"(metal ion binding)|refseq:NP_000191.1|ensembl:ENSG00000205649(gene)|ensembl:ENSG00000282967(gene)|ensembl:ENST00000530128(transcript)|ensembl:ENST00000635585(transcript)|ensembl:ENST00000672568(transcript)|mint:MINT-8415956(identity) - comment:mint - comment:mint|figure legend:f3 f4 t1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/01 2014/10/16 rogid:rMxS3uspMyQcE6zyqk11Bi01ALY242619 rogid:CEDvaZZ2Azjwy1B6E+ZyYd+UISA9606 intact-crc:25B8420429F588FA|rigid:JwGdfPA/UoKW3okKhPAgFgIoVGw false - uncategorized protein modification:41-41(MINT-8415957) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P95493 uniprotkb:P15516 intact:EBI-8505881|intact:MINT-8415911|uniprotkb:O33441|ensemblbacteria:AAQ65700 intact:EBI-738783|uniprotkb:Q16243|uniprotkb:Q502Z1|ensembl:ENSP00000432561|ensembl:ENSP00000489520|ensembl:ENSP00000500623|ensembl:ENSP00000500810|ensembl:ENSP00000504141 psi-mi:cpg2_porgi(display_long)|uniprotkb:rgpB(gene name)|psi-mi:rgpB(display_short)|uniprotkb:Arg-gingipain(gene name synonym)|uniprotkb:Gingipain 2(gene name synonym)|uniprotkb:RGP-2(gene name synonym)|uniprotkb:prtRII(gene name synonym)|uniprotkb:rgp2(gene name synonym)|uniprotkb:PG_0506(locus name) psi-mi:his3_human(display_long)|uniprotkb:HTN3(gene name)|psi-mi:HTN3(display_short)|uniprotkb:HIS2(gene name synonym)|uniprotkb:Histidine-rich protein 3(gene name synonym)|uniprotkb:PB(gene name synonym)|uniprotkb:Basic histidine-rich protein(gene name synonym) psi-mi:"MI:0435"(protease assay) Chen et al. (2013) mint:MINT-8415905|mint:d-12-02105r1|pubmed:23499434 taxid:242619(porgi)|taxid:242619("Porphyromonas gingivalis (strain ATCC BAA-308 / W83)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8505922|mint:MINT-8415942 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026444|interpro:IPR012600(Propetide, peptidase C25)|interpro:IPR001769(Peptidase C25, gingipain)|interpro:IPR005536(Peptidase C25, C-terminal Ig-like region)|interpro:IPR014756(Immunoglobulin E-set)|refseq:WP_010956050.1|interpro:IPR039392|interpro:IPR029030|interpro:IPR029031|mint:P95493|interpro:IPR038490|interpro:IPR041333|ensemblbacteria:AAQ65700(transcript)|ensemblbacteria:PG_0506(gene)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|rcsb pdb:1CVR|rcsb pdb:4IEF|rcsb pdb:5AG8|rcsb pdb:5AG9|rcsb pdb:5HFS|mint:MINT-8415948(identity) ensembl:ENST00000673563(transcript)|ensembl:ENST00000677679(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR030773|interpro:IPR030774|mint:P15516|reactome:R-HSA-6803157|go:"GO:0046872"(metal ion binding)|refseq:NP_000191.1|ensembl:ENSG00000205649(gene)|ensembl:ENSG00000282967(gene)|ensembl:ENST00000530128(transcript)|ensembl:ENST00000635585(transcript)|ensembl:ENST00000672568(transcript)|mint:MINT-8415944(identity) - comment:mint - comment:mint|figure legend:f3 f4 t1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/01 2014/10/16 rogid:rMxS3uspMyQcE6zyqk11Bi01ALY242619 rogid:CEDvaZZ2Azjwy1B6E+ZyYd+UISA9606 intact-crc:9141BB3B996A0DFD|rigid:JwGdfPA/UoKW3okKhPAgFgIoVGw false - uncategorized protein modification:31-31(MINT-8415945) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P95493 uniprotkb:P15516 intact:EBI-8505881|intact:MINT-8415911|uniprotkb:O33441|ensemblbacteria:AAQ65700 intact:EBI-738783|uniprotkb:Q16243|uniprotkb:Q502Z1|ensembl:ENSP00000432561|ensembl:ENSP00000489520|ensembl:ENSP00000500623|ensembl:ENSP00000500810|ensembl:ENSP00000504141 psi-mi:cpg2_porgi(display_long)|uniprotkb:rgpB(gene name)|psi-mi:rgpB(display_short)|uniprotkb:Arg-gingipain(gene name synonym)|uniprotkb:Gingipain 2(gene name synonym)|uniprotkb:RGP-2(gene name synonym)|uniprotkb:prtRII(gene name synonym)|uniprotkb:rgp2(gene name synonym)|uniprotkb:PG_0506(locus name) psi-mi:his3_human(display_long)|uniprotkb:HTN3(gene name)|psi-mi:HTN3(display_short)|uniprotkb:HIS2(gene name synonym)|uniprotkb:Histidine-rich protein 3(gene name synonym)|uniprotkb:PB(gene name synonym)|uniprotkb:Basic histidine-rich protein(gene name synonym) psi-mi:"MI:0435"(protease assay) Chen et al. (2013) mint:MINT-8415905|mint:d-12-02105r1|pubmed:23499434 taxid:242619(porgi)|taxid:242619("Porphyromonas gingivalis (strain ATCC BAA-308 / W83)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8505970|mint:MINT-8415972 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026444|interpro:IPR012600(Propetide, peptidase C25)|interpro:IPR001769(Peptidase C25, gingipain)|interpro:IPR005536(Peptidase C25, C-terminal Ig-like region)|interpro:IPR014756(Immunoglobulin E-set)|refseq:WP_010956050.1|interpro:IPR039392|interpro:IPR029030|interpro:IPR029031|mint:P95493|interpro:IPR038490|interpro:IPR041333|ensemblbacteria:AAQ65700(transcript)|ensemblbacteria:PG_0506(gene)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|rcsb pdb:1CVR|rcsb pdb:4IEF|rcsb pdb:5AG8|rcsb pdb:5AG9|rcsb pdb:5HFS|mint:MINT-8415974(identity) ensembl:ENST00000673563(transcript)|ensembl:ENST00000677679(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR030773|interpro:IPR030774|mint:P15516|reactome:R-HSA-6803157|go:"GO:0046872"(metal ion binding)|refseq:NP_000191.1|ensembl:ENSG00000205649(gene)|ensembl:ENSG00000282967(gene)|ensembl:ENST00000530128(transcript)|ensembl:ENST00000635585(transcript)|ensembl:ENST00000672568(transcript)|mint:MINT-8415976(identity) - comment:mint - comment:mint|figure legend:f3 f4 t1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/01 2014/10/16 rogid:rMxS3uspMyQcE6zyqk11Bi01ALY242619 rogid:CEDvaZZ2Azjwy1B6E+ZyYd+UISA9606 intact-crc:5367A311F4817F6B|rigid:JwGdfPA/UoKW3okKhPAgFgIoVGw false - uncategorized protein modification:24-24(MINT-8415977) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P95493 uniprotkb:P15516 intact:EBI-8505881|intact:MINT-8415911|uniprotkb:O33441|ensemblbacteria:AAQ65700 intact:EBI-738783|uniprotkb:Q16243|uniprotkb:Q502Z1|ensembl:ENSP00000432561|ensembl:ENSP00000489520|ensembl:ENSP00000500623|ensembl:ENSP00000500810|ensembl:ENSP00000504141 psi-mi:cpg2_porgi(display_long)|uniprotkb:rgpB(gene name)|psi-mi:rgpB(display_short)|uniprotkb:Arg-gingipain(gene name synonym)|uniprotkb:Gingipain 2(gene name synonym)|uniprotkb:RGP-2(gene name synonym)|uniprotkb:prtRII(gene name synonym)|uniprotkb:rgp2(gene name synonym)|uniprotkb:PG_0506(locus name) psi-mi:his3_human(display_long)|uniprotkb:HTN3(gene name)|psi-mi:HTN3(display_short)|uniprotkb:HIS2(gene name synonym)|uniprotkb:Histidine-rich protein 3(gene name synonym)|uniprotkb:PB(gene name synonym)|uniprotkb:Basic histidine-rich protein(gene name synonym) psi-mi:"MI:0435"(protease assay) Chen et al. (2013) mint:MINT-8415905|mint:d-12-02105r1|pubmed:23499434 taxid:242619(porgi)|taxid:242619("Porphyromonas gingivalis (strain ATCC BAA-308 / W83)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8505986|mint:MINT-8415984 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026444|interpro:IPR012600(Propetide, peptidase C25)|interpro:IPR001769(Peptidase C25, gingipain)|interpro:IPR005536(Peptidase C25, C-terminal Ig-like region)|interpro:IPR014756(Immunoglobulin E-set)|refseq:WP_010956050.1|interpro:IPR039392|interpro:IPR029030|interpro:IPR029031|mint:P95493|interpro:IPR038490|interpro:IPR041333|ensemblbacteria:AAQ65700(transcript)|ensemblbacteria:PG_0506(gene)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|rcsb pdb:1CVR|rcsb pdb:4IEF|rcsb pdb:5AG8|rcsb pdb:5AG9|rcsb pdb:5HFS|mint:MINT-8415990(identity) ensembl:ENST00000673563(transcript)|ensembl:ENST00000677679(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR030773|interpro:IPR030774|mint:P15516|reactome:R-HSA-6803157|go:"GO:0046872"(metal ion binding)|refseq:NP_000191.1|ensembl:ENSG00000205649(gene)|ensembl:ENSG00000282967(gene)|ensembl:ENST00000530128(transcript)|ensembl:ENST00000635585(transcript)|ensembl:ENST00000672568(transcript)|mint:MINT-8415986(identity) - comment:mint - comment:mint|figure legend:f3 f4 t1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/01 2014/10/16 rogid:rMxS3uspMyQcE6zyqk11Bi01ALY242619 rogid:CEDvaZZ2Azjwy1B6E+ZyYd+UISA9606 intact-crc:317413FEF30A1FFA|rigid:JwGdfPA/UoKW3okKhPAgFgIoVGw false - uncategorized protein modification:30-30(MINT-8415987) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P95493 uniprotkb:P15516 intact:EBI-8505881|intact:MINT-8415911|uniprotkb:O33441|ensemblbacteria:AAQ65700 intact:EBI-738783|uniprotkb:Q16243|uniprotkb:Q502Z1|ensembl:ENSP00000432561|ensembl:ENSP00000489520|ensembl:ENSP00000500623|ensembl:ENSP00000500810|ensembl:ENSP00000504141 psi-mi:cpg2_porgi(display_long)|uniprotkb:rgpB(gene name)|psi-mi:rgpB(display_short)|uniprotkb:Arg-gingipain(gene name synonym)|uniprotkb:Gingipain 2(gene name synonym)|uniprotkb:RGP-2(gene name synonym)|uniprotkb:prtRII(gene name synonym)|uniprotkb:rgp2(gene name synonym)|uniprotkb:PG_0506(locus name) psi-mi:his3_human(display_long)|uniprotkb:HTN3(gene name)|psi-mi:HTN3(display_short)|uniprotkb:HIS2(gene name synonym)|uniprotkb:Histidine-rich protein 3(gene name synonym)|uniprotkb:PB(gene name synonym)|uniprotkb:Basic histidine-rich protein(gene name synonym) psi-mi:"MI:0435"(protease assay) Chen et al. (2013) mint:MINT-8415905|mint:d-12-02105r1|pubmed:23499434 taxid:242619(porgi)|taxid:242619("Porphyromonas gingivalis (strain ATCC BAA-308 / W83)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8505954|mint:MINT-8415962 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026444|interpro:IPR012600(Propetide, peptidase C25)|interpro:IPR001769(Peptidase C25, gingipain)|interpro:IPR005536(Peptidase C25, C-terminal Ig-like region)|interpro:IPR014756(Immunoglobulin E-set)|refseq:WP_010956050.1|interpro:IPR039392|interpro:IPR029030|interpro:IPR029031|mint:P95493|interpro:IPR038490|interpro:IPR041333|ensemblbacteria:AAQ65700(transcript)|ensemblbacteria:PG_0506(gene)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|rcsb pdb:1CVR|rcsb pdb:4IEF|rcsb pdb:5AG8|rcsb pdb:5AG9|rcsb pdb:5HFS|mint:MINT-8415968(identity) ensembl:ENST00000673563(transcript)|ensembl:ENST00000677679(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR030773|interpro:IPR030774|mint:P15516|reactome:R-HSA-6803157|go:"GO:0046872"(metal ion binding)|refseq:NP_000191.1|ensembl:ENSG00000205649(gene)|ensembl:ENSG00000282967(gene)|ensembl:ENST00000530128(transcript)|ensembl:ENST00000635585(transcript)|ensembl:ENST00000672568(transcript)|mint:MINT-8415964(identity) - comment:mint - comment:mint|figure legend:f3 f4 t1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/01 2014/10/16 rogid:rMxS3uspMyQcE6zyqk11Bi01ALY242619 rogid:CEDvaZZ2Azjwy1B6E+ZyYd+UISA9606 intact-crc:68B8848B06EF0A3D|rigid:JwGdfPA/UoKW3okKhPAgFgIoVGw false - uncategorized protein modification:36-36(MINT-8415965) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P95493 uniprotkb:P15516 intact:EBI-8505881|intact:MINT-8415911|uniprotkb:O33441|ensemblbacteria:AAQ65700 intact:EBI-738783|uniprotkb:Q16243|uniprotkb:Q502Z1|ensembl:ENSP00000432561|ensembl:ENSP00000489520|ensembl:ENSP00000500623|ensembl:ENSP00000500810|ensembl:ENSP00000504141 psi-mi:cpg2_porgi(display_long)|uniprotkb:rgpB(gene name)|psi-mi:rgpB(display_short)|uniprotkb:Arg-gingipain(gene name synonym)|uniprotkb:Gingipain 2(gene name synonym)|uniprotkb:RGP-2(gene name synonym)|uniprotkb:prtRII(gene name synonym)|uniprotkb:rgp2(gene name synonym)|uniprotkb:PG_0506(locus name) psi-mi:his3_human(display_long)|uniprotkb:HTN3(gene name)|psi-mi:HTN3(display_short)|uniprotkb:HIS2(gene name synonym)|uniprotkb:Histidine-rich protein 3(gene name synonym)|uniprotkb:PB(gene name synonym)|uniprotkb:Basic histidine-rich protein(gene name synonym) psi-mi:"MI:0435"(protease assay) Chen et al. (2013) mint:MINT-8415905|mint:d-12-02105r1|pubmed:23499434 taxid:242619(porgi)|taxid:242619("Porphyromonas gingivalis (strain ATCC BAA-308 / W83)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-8506002|mint:MINT-8415994 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026444|interpro:IPR012600(Propetide, peptidase C25)|interpro:IPR001769(Peptidase C25, gingipain)|interpro:IPR005536(Peptidase C25, C-terminal Ig-like region)|interpro:IPR014756(Immunoglobulin E-set)|refseq:WP_010956050.1|interpro:IPR039392|interpro:IPR029030|interpro:IPR029031|mint:P95493|interpro:IPR038490|interpro:IPR041333|ensemblbacteria:AAQ65700(transcript)|ensemblbacteria:PG_0506(gene)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|rcsb pdb:1CVR|rcsb pdb:4IEF|rcsb pdb:5AG8|rcsb pdb:5AG9|rcsb pdb:5HFS|mint:MINT-8415996(identity) ensembl:ENST00000673563(transcript)|ensembl:ENST00000677679(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR030773|interpro:IPR030774|mint:P15516|reactome:R-HSA-6803157|go:"GO:0046872"(metal ion binding)|refseq:NP_000191.1|ensembl:ENSG00000205649(gene)|ensembl:ENSG00000282967(gene)|ensembl:ENST00000530128(transcript)|ensembl:ENST00000635585(transcript)|ensembl:ENST00000672568(transcript)|mint:MINT-8415998(identity) - comment:mint - comment:mint|figure legend:f3 f4 t1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/01 2014/10/16 rogid:rMxS3uspMyQcE6zyqk11Bi01ALY242619 rogid:CEDvaZZ2Azjwy1B6E+ZyYd+UISA9606 intact-crc:F62C1D8AEDC81F32|rigid:JwGdfPA/UoKW3okKhPAgFgIoVGw false - uncategorized protein modification:32-32(MINT-8415999) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry)