#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8NBT2 intact:EBI-6377335 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:p27958-pro_0000037566(display_long) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P57682 intact:EBI-6377335 intact:EBI-8472267|uniprotkb:Q6PIR1|uniprotkb:Q86TN0|intact:MINT-4786517|uniprotkb:Q9P2X6|ensembl:ENSP00000261438 psi-mi:p27958-pro_0000037566(display_long) psi-mi:klf3_human(display_long)|uniprotkb:KLF3(gene name)|psi-mi:KLF3(display_short)|uniprotkb:BKLF(gene name synonym)|uniprotkb:Basic krueppel-like factor(gene name synonym)|uniprotkb:CACCC-box-binding protein BKLF(gene name synonym)|uniprotkb:TEF-2(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_057615.3|ensembl:ENSG00000109787(gene)|ensembl:ENST00000261438(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0046872"(metal ion binding)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P57682 - chain-seq-start:2|chain-seq-end:191 comment:mint|comment:homomint|function:Binds to the CACCC box. May play a role in hematopoiesis figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:iu5f7gyHncp/HoKDVBWll3+ubIA9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q6DCA0 intact:EBI-6377335 intact:EBI-5774304|uniprotkb:B4E276|ensembl:ENSP00000272647|ensembl:ENSP00000376726 psi-mi:p27958-pro_0000037566(display_long) psi-mi:amerl_human(display_long)|uniprotkb:AMMECR1L(gene name)|psi-mi:AMMECR1L(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001186069.1|refseq:NP_113633.2|ensembl:ENSG00000144233(gene)|ensembl:ENST00000272647(transcript)|ensembl:ENST00000393001(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR002733(AMMECR1)|interpro:IPR023473|interpro:IPR027485|interpro:IPR036071 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:jJvwBNzZ9acbrtTddeTmrbN76FU9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9Y6V0 intact:EBI-6377335 intact:EBI-7600273|uniprotkb:A6NNX9|intact:MINT-4542387|uniprotkb:Q9UIV2|uniprotkb:Q9Y6U9|uniprotkb:A4D1A7|uniprotkb:Q08E72|uniprotkb:Q9BVC8|uniprotkb:O60305|uniprotkb:O43373|intact:EBI-28967684|ensembl:ENSP00000334319 psi-mi:p27958-pro_0000037566(display_long) psi-mi:pclo_human(display_long)|uniprotkb:PCLO(gene name)|psi-mi:PCLO(display_short)|uniprotkb:ACZ(gene name synonym)|uniprotkb:KIAA0559(gene name synonym)|uniprotkb:Aczonin(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSP00000334319|ensembl:ENST00000423517|ensembl:ENSP00000388393|ensembl:ENST00000618073|ensembl:ENSP00000482390|refseq:NP_055325.2|refseq:NP_149015.2|ensembl:ENSG00000186472(gene)|ensembl:ENST00000333891(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030424"(axon)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0045202"(synapse)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1904071"(presynaptic active zone assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR030629|interpro:IPR035892|interpro:IPR036034|interpro:IPR042720|rcsb pdb:1UJD|reactome:R-HSA-9662360 - chain-seq-start:2|chain-seq-end:191 function:May act as a scaffolding protein involved in the organization of synaptic active zones and in synaptic vesicle trafficking|comment:mint|comment:homomint figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:V3ei7kBzjfwwNZUYH7eaIQ7tZIM9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q96PT4 intact:EBI-6377335 intact:EBI-7964721|intact:MINT-7970020|uniprotkb:Q9UND2 psi-mi:p27958-pro_0000037566(display_long) psi-mi:dux3_human(display_long)|uniprotkb:DUX3(gene name)|psi-mi:DUX3(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) interpro:IPR009057(Homeodomain-like)|interpro:IPR001356(Homeobox)|interpro:IPR000047(Helix-turn-helix motif, lambda-like repressor)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II) - chain-seq-start:2|chain-seq-end:191 comment:mint figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:cDuQ26r3Hw+4IMmVW66eLnkB6l09606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P26583 intact:EBI-6377335 intact:EBI-1057009|uniprotkb:Q5U072|uniprotkb:D3DP37|uniprotkb:B2R4K8|ensembl:ENSP00000296503|ensembl:ENSP00000393448|ensembl:ENSP00000404912 psi-mi:p27958-pro_0000037566(display_long) psi-mi:hmgb2_human(display_long)|uniprotkb:HMGB2(gene name)|psi-mi:HMGB2(display_short)|uniprotkb:HMG2(gene name synonym)|uniprotkb:High mobility group protein 2(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001124160.1|refseq:NP_001124161.1|refseq:NP_002120.1|ensembl:ENSG00000164104(gene)|ensembl:ENST00000296503(transcript)|ensembl:ENST00000438704(transcript)|ensembl:ENST00000446922(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032075"(positive regulation of nuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0042056"(chemoattractant activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0044378"(non-sequence-specific DNA binding, bending)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR036910|mint:P26583|reactome:R-HSA-140342 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:ACzaSeIwT3vM4ZgpCSSlzA6nd4U9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q96B01 intact:EBI-6377335 intact:EBI-1178724|uniprotkb:O43403|uniprotkb:Q7Z779|uniprotkb:A8K7D3|ensembl:ENSP00000228843 psi-mi:p27958-pro_0000037566(display_long) psi-mi:r51a1_human(display_long)|uniprotkb:RAD51-interacting protein(gene name synonym)|uniprotkb:RAD51AP1(gene name)|psi-mi:RAD51AP1(display_short)|uniprotkb:PIR51(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001124334.1|refseq:NP_006470.1|ensembl:ENSG00000111247(gene)|ensembl:ENST00000228843(transcript)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0062037"(D-loop DNA binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR026632|interpro:IPR031419|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|dip:DIP-35257N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:5f/zzkdZZSmaPFxkg52s60rDnqQ9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q16600 intact:EBI-6377335 intact:EBI-8787052|uniprotkb:Q5T1G9|uniprotkb:Q8TAS5|ensembl:ENSP00000307774|ensembl:ENSP00000363569|ensembl:ENSP00000398202|ensembl:ENSP00000443907 psi-mi:p27958-pro_0000037566(display_long) psi-mi:zn239_human(display_long)|uniprotkb:ZNF239(gene name)|psi-mi:ZNF239(display_short)|uniprotkb:HOK2(gene name synonym)|uniprotkb:MOK2(gene name synonym)|uniprotkb:Zinc finger protein HOK-2(gene name synonym)|uniprotkb:Zinc finger protein MOK-2(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:XP_011538540.1|refseq:NP_001092752.1|refseq:NP_001092753.1|refseq:NP_001092754.1|refseq:NP_005665.2|refseq:XP_005271889.1|refseq:NP_001311276.1|refseq:NP_001311277.1|refseq:NP_001311278.1|refseq:NP_001311279.1|refseq:NP_001311280.1|refseq:XP_006718066.1|ensembl:ENSG00000196793(gene)|ensembl:ENST00000306006(transcript)|ensembl:ENST00000374446(transcript)|ensembl:ENST00000426961(transcript)|ensembl:ENST00000535642(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:+482tCuKCEL0mYED/gGVNpSdj8k9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:O14965 intact:EBI-6377335 intact:EBI-448680|uniprotkb:O60445|uniprotkb:O75873|uniprotkb:Q9BQD6|uniprotkb:Q9UPG5|uniprotkb:E1P5F9|ensembl:ENSP00000216911|ensembl:ENSP00000321591|ensembl:ENSP00000360407|ensembl:ENSP00000379247|ensembl:ENSP00000379249|ensembl:ENSP00000379250|ensembl:ENSP00000379251 psi-mi:p27958-pro_0000037566(display_long) psi-mi:aurka_human(display_long)|uniprotkb:AIRK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 15(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 1(gene name synonym)|uniprotkb:Breast tumor-amplified kinase(gene name synonym)|uniprotkb:STK6(gene name synonym)|uniprotkb:AIK(gene name synonym)|uniprotkb:ARK1(gene name synonym)|uniprotkb:AURA(gene name synonym)|uniprotkb:BTAK(gene name synonym)|uniprotkb:STK15(gene name synonym)|uniprotkb:AURKA(gene name)|psi-mi:AURKA(display_short)|uniprotkb:AYK1(gene name synonym)|uniprotkb:IAK1(gene name synonym)|uniprotkb:Aurora 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 6(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-A(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_003591.2|refseq:NP_940835.1|refseq:NP_940836.1|refseq:NP_940837.1|refseq:NP_940838.1|refseq:NP_940839.1|refseq:NP_001310232.1|refseq:NP_001310233.1|refseq:NP_001310234.1|refseq:XP_016883524.1|dip:DIP-33068N|rcsb pdb:3LAU|rcsb pdb:3M11|rcsb pdb:3MYG|rcsb pdb:3NRM|rcsb pdb:3O50|rcsb pdb:3O51|rcsb pdb:3P9J|rcsb pdb:3QBN|rcsb pdb:3R21|rcsb pdb:3R22|rcsb pdb:3UNZ|rcsb pdb:3UO4|rcsb pdb:3UO5|rcsb pdb:3UO6|rcsb pdb:3UOD|rcsb pdb:3UOH|rcsb pdb:3UOJ|rcsb pdb:3UOK|rcsb pdb:3UOL|rcsb pdb:3UP2|rcsb pdb:3UP7|rcsb pdb:3W10|rcsb pdb:3W16|rcsb pdb:3W18|rcsb pdb:3W2C|rcsb pdb:4B0G|rcsb pdb:4BN1|rcsb pdb:4BYI|rcsb pdb:4BYJ|rcsb pdb:4C3P|rcsb pdb:4C3R|rcsb pdb:4CEG|rcsb pdb:4DEA|rcsb pdb:4DEB|rcsb pdb:4DED|rcsb pdb:4DEE|rcsb pdb:4DHF|rcsb pdb:4J8M|rcsb pdb:4J8N|rcsb pdb:4JAI|rcsb pdb:4JAJ|rcsb pdb:4JBO|rcsb pdb:4JBP|rcsb pdb:4JBQ|rcsb pdb:4O0S|rcsb pdb:4O0U|rcsb pdb:4O0W|rcsb pdb:4PRJ|rcsb pdb:4UYN|rcsb pdb:4UZD|rcsb pdb:4UZH|rcsb pdb:4ZS0|rcsb pdb:3VAP|rcsb pdb:4ZTQ|rcsb pdb:4ZTR|rcsb pdb:5AAD|rcsb pdb:5AAE|rcsb pdb:5AAF|rcsb pdb:5AAG|rcsb pdb:5DN3|rcsb pdb:5DNR|rcsb pdb:5DOS|rcsb pdb:5DPV|rcsb pdb:5DR2|rcsb pdb:5DR6|rcsb pdb:5DR9|rcsb pdb:5DRD|rcsb pdb:5DT0|rcsb pdb:5DT3|rcsb pdb:5DT4|rcsb pdb:5EW9|rcsb pdb:5G15|rcsb pdb:5G1X|rcsb pdb:5L8J|rcsb pdb:5L8K|rcsb pdb:5L8L|rcsb pdb:5LXM|rcsb pdb:5OBJ|rcsb pdb:5OBR|rcsb pdb:5ODT|rcsb pdb:5ONE|rcsb pdb:5ORL|rcsb pdb:5ORN|rcsb pdb:5ORO|rcsb pdb:5ORP|rcsb pdb:5ORR|rcsb pdb:5ORS|rcsb pdb:5ORT|rcsb pdb:5ORV|rcsb pdb:5ORW|rcsb pdb:5ORX|rcsb pdb:5ORY|rcsb pdb:5ORZ|rcsb pdb:5OS0|rcsb pdb:5OS1|rcsb pdb:5OS2|rcsb pdb:5OS3|rcsb pdb:5OS4|rcsb pdb:5OS5|rcsb pdb:5OS6|rcsb pdb:5OSD|rcsb pdb:5OSE|rcsb pdb:5OSF|rcsb pdb:5ZAN|rcsb pdb:6C2R|rcsb pdb:6C2T|rcsb pdb:6C83|rcsb pdb:6CPE|rcsb pdb:6CPF|rcsb pdb:6CPG|rcsb pdb:6GRA|rcsb pdb:6HJJ|rcsb pdb:6HJK|rcsb pdb:6I2U|rcsb pdb:6R49|rcsb pdb:6R4A|rcsb pdb:6R4B|rcsb pdb:4ZTS|rcsb pdb:6R4C|rcsb pdb:6R4D|rcsb pdb:6VPG|rcsb pdb:6VPH|rcsb pdb:6VPI|rcsb pdb:6VPJ|rcsb pdb:6VPL|rcsb pdb:6VPM|rcsb pdb:6XKA|rcsb pdb:6Z4Y|rcsb pdb:7AYH|rcsb pdb:7AYI|reactome:R-HSA-174178|reactome:R-HSA-2565942|reactome:R-HSA-4615885|reactome:R-HSA-6804114|reactome:R-HSA-6804756|reactome:R-HSA-8854050|reactome:R-HSA-8854518|reactome:R-HSA-8854521|ensembl:ENSG00000087586(gene)|ensembl:ENST00000312783(transcript)|ensembl:ENST00000347343(transcript)|ensembl:ENST00000371356(transcript)|ensembl:ENST00000395911(transcript)|ensembl:ENST00000395913(transcript)|ensembl:ENST00000395914(transcript)|ensembl:ENST00000395915(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0009611"(response to wounding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0042585"(germinal vesicle)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043203"(axon hillock)|go:"GO:0045120"(pronucleus)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097421"(liver regeneration)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2C6D|rcsb pdb:2C6E|rcsb pdb:2DWB|rcsb pdb:2J4Z|rcsb pdb:2J50|rcsb pdb:2NP8|rcsb pdb:2W1C|rcsb pdb:2W1D|rcsb pdb:2W1E|rcsb pdb:2W1F|interpro:IPR030611|rcsb pdb:2W1G|rcsb pdb:2WQE|rcsb pdb:2WTV|rcsb pdb:2WTW|rcsb pdb:2X6D|rcsb pdb:2X6E|rcsb pdb:2X81|rcsb pdb:2XNE|rcsb pdb:2XNG|rcsb pdb:2XRU|rcsb pdb:3COH|rcsb pdb:3E5A|rcsb pdb:3EFW|rcsb pdb:3FDN|interpro:IPR030616|mint:O14965|rcsb pdb:1MQ4|rcsb pdb:1MUO|rcsb pdb:1OL5|rcsb pdb:1OL6|rcsb pdb:1OL7|rcsb pdb:2BMC|rcsb pdb:3H0Y|rcsb pdb:3H0Z|rcsb pdb:3H10|rcsb pdb:3HA6|rcsb pdb:3K5U - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:UT4ih1hMN2xMvAC3hDznAJOW+/E9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P01100 intact:EBI-6377335 intact:EBI-852851|uniprotkb:P18849|uniprotkb:A8K4E2|uniprotkb:B4DQ65|ensembl:ENSP00000306245 psi-mi:p27958-pro_0000037566(display_long) psi-mi:fos_human(display_long)|uniprotkb:Cellular oncogene fos(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 7(gene name synonym)|uniprotkb:FOS(gene name)|psi-mi:FOS(display_short)|uniprotkb:G0S7(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_005243.1|dip:DIP-1047N|ensembl:ENSG00000170345(gene)|ensembl:ENST00000303562(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009409"(response to cold)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030431"(sleep)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051591"(response to cAMP)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029816|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1S9K|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-9018519|reactome:R-HSA-9031628|reactome:R-HSA-9634638 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:R09jzTKeAyzIQYTQAsps2UWFyFE9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:O00559 intact:EBI-6377335 intact:EBI-8787095|uniprotkb:Q6IB20|uniprotkb:Q9BS76|uniprotkb:A8K3N6|uniprotkb:Q5Y8C7|ensembl:ENSP00000337675|ensembl:ENSP00000379131|ensembl:ENSP00000477645 psi-mi:p27958-pro_0000037566(display_long) psi-mi:rcas1_human(display_long)|uniprotkb:EBAG9(gene name)|psi-mi:EBAG9(display_short)|uniprotkb:RCAS1(gene name synonym)|uniprotkb:Cancer-associated surface antigen RCAS1(gene name synonym)|uniprotkb:Estrogen receptor-binding fragment-associated gene 9 protein(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:XP_016869449.1|refseq:NP_004206.1|refseq:NP_936056.1|refseq:NP_001265867.1|ensembl:ENSG00000147654(gene)|ensembl:ENST00000337573(transcript)|ensembl:ENST00000395785(transcript)|ensembl:ENST00000620557(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016505"(peptidase activator activity involved in apoptotic process)|go:"GO:0030141"(secretory granule)|interpro:IPR017025(Cancer-associated antigen RCAS1)|reactome:R-HSA-9018519 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:/4Zg2jOkRmcxYfNTJVTcJjEx2/49606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8N5Y2 intact:EBI-6377335 intact:EBI-2560796|ensembl:ENSP00000312244|uniprotkb:Q9Y5Z8|uniprotkb:Q9UG70|uniprotkb:B7Z227|uniprotkb:B4DUV8|uniprotkb:A6NCU2|uniprotkb:A6NHW8|uniprotkb:A8K165 psi-mi:p27958-pro_0000037566(display_long) psi-mi:ms3l1_human(display_long)|uniprotkb:MSL3(gene name)|psi-mi:MSL3(display_short)|uniprotkb:MSL3L1(gene name synonym)|uniprotkb:Male-specific lethal-3 protein-like 1(gene name synonym)|uniprotkb:Male-specific lethal-3 homolog 1(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000005302(gene)|ensembl:ENST00000312196(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0072487"(MSL complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR037921|interpro:IPR038217|mint:Q8N5Y2|rcsb pdb:2Y0N|rcsb pdb:3OA6|rcsb pdb:3OB9|reactome:R-HSA-3214847|refseq:NP_001180199.1|refseq:NP_523352.1|refseq:NP_523353.2|refseq:NP_006791.2|refseq:NP_001269103.1|refseq:XP_005274497.1|dip:DIP-56857N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:uZsUcEHPwWI+o+d7aGwhfnxVltA9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P54274 intact:EBI-6377335 intact:EBI-710997|uniprotkb:A7XP29|uniprotkb:Q15553|uniprotkb:Q93029|ensembl:ENSP00000276603|uniprotkb:Q8NHT6 psi-mi:p27958-pro_0000037566(display_long) psi-mi:terf1_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 1(gene name synonym)|uniprotkb:NIMA-interacting protein 2(gene name synonym)|uniprotkb:Telomeric protein Pin2/TRF1(gene name synonym)|uniprotkb:TERF1(gene name)|psi-mi:TERF1(display_short)|uniprotkb:PIN2(gene name synonym)|uniprotkb:TRF(gene name synonym)|uniprotkb:TRF1(gene name synonym)|uniprotkb:TRBF1(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_003209.2|refseq:NP_059523.2|ensembl:ENSG00000147601(gene)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|ensembl:ENST00000276603(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016604"(nuclear body)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR036507|mint:P54274|rcsb pdb:1BA5|rcsb pdb:1H6O|rcsb pdb:1ITY|rcsb pdb:1IV6|rcsb pdb:1W0T|rcsb pdb:3BQO|rcsb pdb:3L82|rcsb pdb:5HKP|rcsb pdb:5WIR|rcsb pdb:5XUP|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0090656"(t-circle formation)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904792"(positive regulation of shelterin complex assembly)|go:"GO:1904850"(negative regulation of establishment of protein localization to telomere)|go:"GO:1904911"(negative regulation of establishment of RNA localization to telomere)|go:"GO:1904914"(negative regulation of establishment of protein-containing complex localization to telomere)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|dip:DIP-29412N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:3Tjmp8hqEhLBIQqxxWHntpL4hz49606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q15651 intact:EBI-6377335 intact:EBI-1758705|uniprotkb:Q7RTT0|uniprotkb:Q969M5|uniprotkb:Q9BZT7|uniprotkb:Q5HYD3|uniprotkb:B2RD37|ensembl:ENSP00000341267 psi-mi:p27958-pro_0000037566(display_long) psi-mi:hmgn3_human(display_long)|uniprotkb:HMGN3(gene name)|psi-mi:HMGN3(display_short)|uniprotkb:TRIP7(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 7(gene name synonym)|uniprotkb:PNAS-24(orf name) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001305813.1|refseq:NP_001305814.1|refseq:NP_001305815.1|refseq:NP_001305816.1|refseq:NP_001305817.1|refseq:NP_001188291.1|refseq:NP_001188292.1|refseq:NP_004233.1|refseq:NP_620058.1|ensembl:ENSG00000118418(gene)|ensembl:ENST00000344726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|interpro:IPR031073 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:NezCk0zWZWINpJjwvb3i3SWOuCs9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9UFF9 intact:EBI-6377335 intact:EBI-742299|uniprotkb:O95709|uniprotkb:Q7Z521|uniprotkb:Q9H6Y1|uniprotkb:D3DQI8|uniprotkb:B2RAR8|intact:EBI-10979182|uniprotkb:B0AZS3|uniprotkb:B7Z8R1|ensembl:ENSP00000285896|ensembl:ENSP00000384747|ensembl:ENSP00000430493 psi-mi:p27958-pro_0000037566(display_long) psi-mi:cnot8_human(display_long)|uniprotkb:CNOT8(gene name)|psi-mi:CNOT8(display_short)|uniprotkb:CALIF(gene name synonym)|uniprotkb:POP2(gene name synonym)|uniprotkb:CCR4-associated factor 8(gene name synonym)|uniprotkb:CAF1-like protein(gene name synonym)|uniprotkb:CAF2(gene name synonym)|uniprotkb:Caf1b(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_004770.4|refseq:XP_005268584.1|refseq:NP_001288002.1|refseq:NP_001288003.1|refseq:NP_001288004.1|refseq:NP_001288006.1|refseq:NP_001288009.1|refseq:NP_001288011.1|refseq:NP_001288012.1|refseq:NP_001288015.1|refseq:XP_011536008.1|refseq:XP_011536010.1|refseq:XP_016865537.1|refseq:XP_016865538.1|refseq:XP_016865539.1|refseq:XP_016865540.1|refseq:XP_016865541.1|refseq:XP_016865542.1|refseq:XP_016865543.1|refseq:XP_016865544.1|refseq:XP_016865545.1|refseq:XP_016865546.1|ensembl:ENSG00000155508(gene)|ensembl:ENST00000285896(transcript)|ensembl:ENST00000403027(transcript)|ensembl:ENST00000517876(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR027212|interpro:IPR036397|interpro:IPR039637|mint:Q9UFF9|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-29084N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:pjaQYzYBGJWC7z5R5s8Te+v2sRA9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q14919 intact:EBI-6377335 intact:EBI-712941|uniprotkb:Q13448|ensembl:ENSP00000307850 psi-mi:p27958-pro_0000037566(display_long) psi-mi:nc2a_human(display_long)|uniprotkb:Dr1-associated protein 1(gene name synonym)|uniprotkb:DRAP1(gene name)|psi-mi:DRAP1(display_short)|uniprotkb:Negative cofactor 2-alpha(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_006433.2|reactome:R-HSA-1181150|reactome:R-HSA-1502540|rcsb pdb:1JFI|ensembl:ENSG00000175550(gene)|ensembl:ENST00000312515(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|mint:Q14919 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:ek/+ddQxp2b8JYDGwwBwTX5VYfg9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P37231 intact:EBI-6377335 intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820 psi-mi:p27958-pro_0000037566(display_long) psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q96PI1 intact:EBI-6377335 intact:EBI-8787494|uniprotkb:Q2M1Y7|uniprotkb:Q5T522|ensembl:ENSP00000332163 psi-mi:p27958-pro_0000037566(display_long) psi-mi:sprr4_human(display_long)|uniprotkb:SPRR4(gene name)|psi-mi:SPRR4(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_775103.1|refseq:XP_016855971.1|ensembl:ENSG00000184148(gene)|ensembl:ENST00000328051(transcript)|go:"GO:0005938"(cell cortex)|go:"GO:0031424"(keratinization) - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:qRdoOXMIAp29Qa6c3jOk0Ep+lzU9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P62857 intact:EBI-6377335 intact:EBI-353027|ensembl:ENSP00000472469|uniprotkb:P25112 psi-mi:p27958-pro_0000037566(display_long) psi-mi:rs28_human(display_long)|uniprotkb:RPS28(gene name)|psi-mi:RPS28(display_short)|uniprotkb:Small ribosomal subunit protein eS28(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) mint:P62857|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|ensembl:ENSG00000233927(gene)|ensembl:ENST00000600659(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000289(Ribosomal protein S28e)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028626|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZM7|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001022.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:G4t8mOlzIiHEOXu+uS+AfySWAnM9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P61964 intact:EBI-6377335 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:p27958-pro_0000037566(display_long) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q14247 intact:EBI-6377335 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 psi-mi:p27958-pro_0000037566(display_long) psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q16644 intact:EBI-6377335 intact:EBI-1384657|uniprotkb:B5BU67|ensembl:ENSP00000350639|ensembl:ENSP00000396467|ensembl:ENSP00000478922 psi-mi:p27958-pro_0000037566(display_long) psi-mi:mapk3_human(display_long)|uniprotkb:Chromosome 3p kinase(gene name synonym)|uniprotkb:MAPKAPK3(gene name)|psi-mi:MAPKAPK3(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_004626.1|refseq:NP_001230854.1|refseq:NP_001230855.1|reactome:R-HSA-2559580|reactome:R-HSA-4420097|reactome:R-HSA-450302|ensembl:ENSG00000114738(gene)|ensembl:ENST00000357955(transcript)|ensembl:ENST00000446044(transcript)|ensembl:ENST00000621469(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044351"(macropinocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027442|mint:Q16644|rcsb pdb:3FHR|rcsb pdb:3FXW|rcsb pdb:3R1N|rcsb pdb:3SHE|reactome:R-HSA-171007 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:pb+7uZ1B8LMFi5DrfRi70X9Xbks9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q7Z6M1 intact:EBI-6377335 intact:EBI-3914588|uniprotkb:Q69YR2|uniprotkb:Q86Y76|uniprotkb:Q9BWB1|uniprotkb:Q6IBG7|uniprotkb:Q6P092|uniprotkb:O00568|uniprotkb:Q6FHA4|uniprotkb:A8K403|intact:EBI-28977166|ensembl:ENSP00000362639|ensembl:ENSP00000377683 psi-mi:p27958-pro_0000037566(display_long) psi-mi:rabek_human(display_long)|uniprotkb:RABEPK(gene name)|psi-mi:RABEPK(display_short)|uniprotkb:RAB9P40(gene name synonym)|uniprotkb:40 kDa Rab9 effector protein(gene name synonym)|uniprotkb:p40(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENST00000259460|ensembl:ENSP00000259460|ensembl:ENSP00000362639|ensembl:ENSP00000377683|refseq:NP_001167623.1|refseq:NP_001167624.1|refseq:NP_005824.2|refseq:XP_016869666.1|ensembl:ENSG00000136933(gene)|ensembl:ENST00000373538(transcript)|ensembl:ENST00000394125(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0032588"(trans-Golgi network membrane)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011498(Kelch repeat type 2)|interpro:IPR015915(Kelch-type beta propeller)|reactome:R-HSA-6811440 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:iL/f1TBleqK3UX0iazUKQDaFLd89606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8IW41 intact:EBI-6377335 intact:EBI-1201460|uniprotkb:O60491|uniprotkb:Q86X46|uniprotkb:Q9BVX9|uniprotkb:Q9UG86|uniprotkb:B3KVA5|ensembl:ENSP00000449381 psi-mi:p27958-pro_0000037566(display_long) psi-mi:mapk5_human(display_long)|uniprotkb:MAPKAPK5(gene name)|psi-mi:MAPKAPK5(display_short)|uniprotkb:PRAK(gene name synonym)|uniprotkb:p38-regulated/activated protein kinase(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_003659.2|refseq:NP_620777.1|ensembl:ENSG00000089022(gene)|ensembl:ENST00000551404(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090398"(cellular senescence)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR027442|reactome:R-HSA-2559580|reactome:R-HSA-5687128|reactome:R-HSA-6804756 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:1zo/tqh0/AXCMb9uERCgKWX7RoI9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q99986 intact:EBI-6377335 intact:EBI-1769146|uniprotkb:Q3SYL2|ensembl:ENSP00000216639|ensembl:ENSP00000506151|ensembl:ENSP00000506214|ensembl:ENSP00000506525|ensembl:ENSP00000506648 psi-mi:p27958-pro_0000037566(display_long) psi-mi:vrk1_human(display_long)|uniprotkb:Vaccinia-related kinase 1(gene name synonym)|uniprotkb:VRK1(gene name)|psi-mi:VRK1(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_003375.1|ensembl:ENSG00000100749(gene)|ensembl:ENST00000216639(transcript)|ensembl:ENST00000679816(transcript)|ensembl:ENST00000680756(transcript)|ensembl:ENST00000681344(transcript)|ensembl:ENST00000681355(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005795"(Golgi stack)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0035175"("histone kinase activity (H3-S10 specific)")|go:"GO:0043987"(histone H3-S10 phosphorylation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0072354"("histone kinase activity (H3-T3 specific)")|go:"GO:0072355"(histone H3-T3 phosphorylation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q99986|rcsb pdb:2KTY|rcsb pdb:2KUL|rcsb pdb:2LAV|rcsb pdb:2RSV|rcsb pdb:3OP5|rcsb pdb:5UKF|rcsb pdb:5UVF|rcsb pdb:6AC9|rcsb pdb:6BP0|rcsb pdb:6BRU|rcsb pdb:6BTW|rcsb pdb:6BU6|rcsb pdb:6CFM|rcsb pdb:6CMM|rcsb pdb:6CNX|rcsb pdb:6CQH|rcsb pdb:6CSW|rcsb pdb:6DD4|rcsb pdb:6NPN|rcsb pdb:6VXU|rcsb pdb:6VZH|rcsb pdb:7M10|reactome:R-HSA-2980766|reactome:R-HSA-2995383 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:yT5v4RDikIcBEDKbg0m9H1el82o9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9H8X2 intact:EBI-6377335 intact:EBI-8786596|uniprotkb:Q5T9F7|uniprotkb:Q9H7V8|ensembl:ENSP00000287996 psi-mi:p27958-pro_0000037566(display_long) psi-mi:ippk_human(display_long)|uniprotkb:IPPK(gene name)|psi-mi:IPPK(display_short)|uniprotkb:C9orf12(gene name synonym)|uniprotkb:IPK1 homolog(gene name synonym)|uniprotkb:Inositol-1,3,4,5,6-pentakisphosphate 2-kinase(gene name synonym)|uniprotkb:"Ins(1,3,4,5,6)P5 2-kinase"(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_073592.1|ensembl:ENSG00000127080(gene)|ensembl:ENST00000287996(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0035299"(inositol pentakisphosphate 2-kinase activity)|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0052746"(inositol phosphorylation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR009286(Protein of unknown function DUF941)|interpro:IPR043001|reactome:R-HSA-1855167|reactome:R-HSA-1855191 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:5yXdmzUu2hhufMg5stE07tU5Nes9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P19784 intact:EBI-6377335 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:p27958-pro_0000037566(display_long) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8N5I9 intact:EBI-6377335 intact:EBI-3916179|ensembl:ENSP00000447057 psi-mi:p27958-pro_0000037566(display_long) psi-mi:nopc1_human(display_long)|uniprotkb:NOPCHAP1(gene name)|psi-mi:NOPCHAP1(display_short)|uniprotkb:C12orf45(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000151131(gene)|ensembl:ENST00000552951(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0062064"(box C/D snoRNP complex binding)|interpro:IPR027921|refseq:NP_689531.2 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:IceY1EEQ77ZH7p92dxExlJMyfsA9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8N6L7 intact:EBI-6377335 intact:EBI-8787626|ensembl:ENSP00000366528 psi-mi:p27958-pro_0000037566(display_long) psi-mi:tm252_human(display_long)|uniprotkb:TMEM252(gene name)|psi-mi:TMEM252(display_short)|uniprotkb:C9orf71(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSP00000366528|refseq:NP_694969.1|ensembl:ENSG00000181778(gene)|ensembl:ENST00000377311(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031363 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:6SXzYh9exHy9BoGURX/elvefNiI9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9P270 intact:EBI-6377335 intact:EBI-3959887|uniprotkb:A8K4P1|uniprotkb:Q8N5R3|ensembl:ENSP00000264313 psi-mi:p27958-pro_0000037566(display_long) psi-mi:slai2_human(display_long)|uniprotkb:SLAIN2(gene name)|psi-mi:SLAIN2(display_short)|uniprotkb:KIAA1458(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_065897.1|ensembl:ENSG00000109171(gene)|ensembl:ENST00000264313(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR026179|mint:Q9P270|rcsb pdb:3RDV - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:r8OlU6BASEpehSYkbA9b3F3q5go9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8NEG0 intact:EBI-6377335 intact:EBI-752049|uniprotkb:B2R6Y6|ensembl:ENSP00000315247 psi-mi:p27958-pro_0000037566(display_long) psi-mi:fa71c_human(display_long)|uniprotkb:FAM71C(gene name)|psi-mi:FAM71C(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_699195.1|ensembl:ENSG00000180219(gene)|ensembl:ENST00000324341(transcript)|interpro:IPR022168 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:P9mfeXC1WToJf5z8CihCBK3Enwk9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9BU76 intact:EBI-6377335 intact:EBI-742459|uniprotkb:Q6P5Y0|uniprotkb:Q6ZTZ6|uniprotkb:Q6ZWA6|uniprotkb:Q8IZH3|ensembl:ENSP00000272139 psi-mi:p27958-pro_0000037566(display_long) psi-mi:mmta2_human(display_long)|uniprotkb:MMTAG2(gene name)|psi-mi:MMTAG2(display_short)|uniprotkb:C1orf35(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_077295.1|mint:Q9BU76|reactome:R-HSA-6798695|ensembl:ENSG00000143793(gene)|ensembl:ENST00000272139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0034774"(secretory granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019315|interpro:IPR039207 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:TwnLhBYwwR6yPCw3sd7g/sPHJd09606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9BUV0 intact:EBI-6377335 intact:EBI-745604|uniprotkb:Q49AA4|uniprotkb:Q5TH71|uniprotkb:Q9GZP6|uniprotkb:A8K917|ensembl:ENSP00000243189 psi-mi:p27958-pro_0000037566(display_long) psi-mi:rsrp1_human(display_long)|uniprotkb:RSRP1(gene name)|psi-mi:RSRP1(display_short)|uniprotkb:C1orf63(gene name synonym)|uniprotkb:HT033(orf name)|uniprotkb:NPD014(orf name) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_064713.3|refseq:XP_011540099.1|ensembl:ENSG00000117616(gene)|ensembl:ENST00000243189(transcript)|interpro:IPR029656|mint:Q9BUV0|refseq:NP_001308701.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:IugruP8t4mowi3v7H1DCMkmPBhI9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8NEG7 intact:EBI-6377335 intact:EBI-3957009|uniprotkb:A6X8I5|ensembl:ENSP00000391524 psi-mi:p27958-pro_0000037566(display_long) psi-mi:den6b_human(display_long)|uniprotkb:DENND6B(gene name)|psi-mi:DENND6B(display_short)|uniprotkb:DENN domain-containing protein 6B(gene name synonym)|uniprotkb:FAM116B(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) interpro:IPR024224|interpro:IPR037516|reactome:R-HSA-8876198|refseq:NP_001001794.3|ensembl:ENSG00000205593(gene)|ensembl:ENST00000413817(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0055037"(recycling endosome)|interpro:IPR018307 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:2J4E9XtJ5uKlO4xfX/27xRqv3ZY9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8IXS8 intact:EBI-6377335 intact:EBI-8787606|uniprotkb:B2RCG7|uniprotkb:Q4ZG87|uniprotkb:Q53TX6|ensembl:ENSP00000393667 psi-mi:p27958-pro_0000037566(display_long) psi-mi:f126b_human(display_long)|uniprotkb:FAM126B(gene name)|psi-mi:FAM126B(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_776183.1|refseq:NP_001308547.1|refseq:NP_001308548.1|refseq:NP_001308550.1|refseq:NP_001308551.1|refseq:NP_001308556.1|refseq:XP_016859370.1|ensembl:ENSG00000155744(gene)|ensembl:ENST00000418596(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR018619 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:I66/zTS0nPVPDIA5Gw+hIaSl49c9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8IXS8 intact:EBI-6377335 intact:EBI-8787606|uniprotkb:B2RCG7|uniprotkb:Q4ZG87|uniprotkb:Q53TX6|ensembl:ENSP00000393667 psi-mi:p27958-pro_0000037566(display_long) psi-mi:f126b_human(display_long)|uniprotkb:FAM126B(gene name)|psi-mi:FAM126B(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_776183.1|refseq:NP_001308547.1|refseq:NP_001308548.1|refseq:NP_001308550.1|refseq:NP_001308551.1|refseq:NP_001308556.1|refseq:XP_016859370.1|ensembl:ENSG00000155744(gene)|ensembl:ENST00000418596(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR018619 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:I66/zTS0nPVPDIA5Gw+hIaSl49c9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9BWK5 intact:EBI-6377335 intact:EBI-8787584|uniprotkb:Q6NWZ4|uniprotkb:Q6ZNR5|uniprotkb:A0A024R780|uniprotkb:A0A087WWQ8|ensembl:ENSP00000376823 psi-mi:p27958-pro_0000037566(display_long) psi-mi:cyren_human(display_long)|uniprotkb:CYREN(gene name)|psi-mi:CYREN(display_short)|uniprotkb:C7orf49(gene name synonym)|uniprotkb:MRI(gene name synonym)|uniprotkb:Modulator of retrovirus infection homolog(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001292558.1|refseq:NP_001230678.1|refseq:NP_001230680.1|refseq:NP_001230681.1|refseq:NP_001230682.1|refseq:NP_001230683.1|refseq:NP_001230684.1|refseq:NP_076938.2|refseq:XP_016868078.1|refseq:XP_016868079.1|refseq:XP_016868080.1|refseq:XP_016868082.1|refseq:XP_016868083.1|refseq:XP_016868084.1|ensembl:ENSG00000122783(gene)|ensembl:ENST00000393114(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0035861"(site of double-strand break)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR028278|rcsb pdb:6TYU - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:WoPZ3Denw8rbiCHL0GMZC0DJ+Hw9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9Y2S6 intact:EBI-6377335 intact:EBI-6269510|ensembl:ENSP00000397843|uniprotkb:Q9P052 psi-mi:p27958-pro_0000037566(display_long) psi-mi:tma7_human(display_long)|uniprotkb:TMA7(gene name)|psi-mi:TMA7(display_short)|uniprotkb:CCDC72(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 72(gene name synonym)|uniprotkb:HSPC016(orf name)|uniprotkb:HSPC330(orf name) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) interpro:IPR015157(Translation machinery associated TMA7)|ensembl:ENSG00000232112(gene)|ensembl:ENST00000438607(transcript)|go:"GO:0002181"(cytoplasmic translation)|refseq:NP_057017.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:Lwy203R7sJAt/S3tOTGPIeqS5KI9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9H9L4 intact:EBI-6377335 intact:EBI-2560840|uniprotkb:Q8N3B5|uniprotkb:Q9NX51|uniprotkb:Q96CV0|ensembl:ENSP00000415436 psi-mi:p27958-pro_0000037566(display_long) psi-mi:kanl2_human(display_long)|uniprotkb:KANSL2(gene name)|psi-mi:KANSL2(display_short)|uniprotkb:C12orf41(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_060292.3|ensembl:ENSG00000139620(gene)|ensembl:ENST00000420613(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|mint:Q9H9L4|rcsb pdb:4CY2|reactome:R-HSA-3214847 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:ymOXqnaeH6HuGcHPg4R2XVmWAz89606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q96E40 intact:EBI-6377335 intact:EBI-722584|uniprotkb:Q9UGQ0|ensembl:ENSP00000348659|ensembl:ENSP00000361209 psi-mi:p27958-pro_0000037566(display_long) psi-mi:saca9_human(display_long)|uniprotkb:SPACA9(gene name)|psi-mi:SPACA9(display_short)|uniprotkb:C9orf9(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_061829.3|ensembl:ENSG00000165698(gene)|ensembl:ENST00000356311(transcript)|ensembl:ENST00000372136(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0097546"(ciliary base)|interpro:IPR027818|refseq:NP_001303826.1|refseq:NP_001303827.1|refseq:NP_001303829.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:gFAD0V0xCuufALDBqCTdyofBB/U9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:O14598 intact:EBI-6377335 intact:EBI-8787564|ensembl:ENSP00000250823|ensembl:ENSP00000250825 psi-mi:p27958-pro_0000037566(display_long) psi-mi:vcy1_human(display_long)|uniprotkb:VCY(gene name)|psi-mi:VCY(display_short)|uniprotkb:VCY1B(gene name)|psi-mi:VCY1B(display_short)|uniprotkb:BPY1(gene name synonym)|uniprotkb:VCY1A(gene name synonym)|uniprotkb:BPY1B(gene name synonym)|uniprotkb:Basic charge, Y-linked 1(gene name synonym)|uniprotkb:Variably charged protein Y(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_004670.1|refseq:NP_870996.1|ensembl:ENSG00000129862(gene)|ensembl:ENSG00000129864(gene)|ensembl:ENST00000250823(transcript)|ensembl:ENST00000250825(transcript)|go:"GO:0007420"(brain development)|interpro:IPR026653 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:v4ALk07rXS/j+DlTdYWFiVLcxQs9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9H7E9 intact:EBI-6377335 intact:EBI-715389|uniprotkb:A6NGC0|uniprotkb:Q96BT8|ensembl:ENSP00000330361 psi-mi:p27958-pro_0000037566(display_long) psi-mi:ch033_human(display_long)|uniprotkb:C8orf33(gene name)|psi-mi:C8orf33(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_075568.1|ensembl:ENSG00000182307(gene)|ensembl:ENST00000331434(transcript)|interpro:IPR029274|mint:Q9H7E9 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:R2UNBJ/dYewCXrmuO3E9apROd+Q9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9Y3C1 intact:EBI-6377335 intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832 psi-mi:p27958-pro_0000037566(display_long) psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8IWP9 intact:EBI-6377335 intact:EBI-355471|uniprotkb:Q9Y430|uniprotkb:Q32NC7|uniprotkb:Q66K67|uniprotkb:Q96E23|uniprotkb:E1P591 psi-mi:p27958-pro_0000037566(display_long) psi-mi:cc28a_human(display_long)|uniprotkb:CCDC28A(gene name)|psi-mi:CCDC28A(display_short)|uniprotkb:C6orf80(gene name synonym)|uniprotkb:CCRL1AP(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) interpro:IPR025271|refseq:NP_056254.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:P6RRe4x1NvXrcimUTKQI5q9ifb89606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P60006 intact:EBI-6377335 intact:EBI-8787535|uniprotkb:G3V1Q3|uniprotkb:Q9CXK2|uniprotkb:Q9Y269|ensembl:ENSP00000227618|ensembl:ENSP00000440002|ensembl:ENSP00000440983|ensembl:ENSP00000443383|ensembl:ENSP00000443911|ensembl:ENSP00000446383|ensembl:ENSP00000446412 psi-mi:p27958-pro_0000037566(display_long) psi-mi:apc15_human(display_long)|uniprotkb:ANAPC15(gene name)|psi-mi:ANAPC15(display_short)|uniprotkb:C11orf51(gene name synonym)|uniprotkb:HSPC020(orf name) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_054761.1|refseq:NP_001265414.1|refseq:NP_001265415.1|refseq:NP_001265416.1|refseq:NP_001265417.1|refseq:NP_001265418.1|refseq:NP_001265419.1|refseq:NP_001265420.1|refseq:NP_001265421.1|refseq:NP_001265422.1|refseq:NP_001265423.1|refseq:XP_016872985.1|refseq:XP_016872986.1|dip:DIP-61021N|ensembl:ENSG00000110200(gene)|ensembl:ENST00000227618(transcript)|ensembl:ENST00000535234(transcript)|ensembl:ENST00000535503(transcript)|ensembl:ENST00000538393(transcript)|ensembl:ENST00000538919(transcript)|ensembl:ENST00000542531(transcript)|ensembl:ENST00000545944(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|interpro:IPR026182|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:nQTEwP1LHxaqHPJEYm/gr3bCi649606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:O95424 intact:EBI-6377335 intact:EBI-724515|uniprotkb:B2RAA7|ensembl:ENSP00000330509|ensembl:ENSP00000482265|ensembl:ENSP00000493467 psi-mi:p27958-pro_0000037566(display_long) psi-mi:dexi_human(display_long)|uniprotkb:DEXI(gene name)|psi-mi:DEXI(display_short)|uniprotkb:MYLE(gene name synonym)|uniprotkb:Protein MYLE(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_054734.2|ensembl:ENSG00000182108(gene)|ensembl:ENST00000331808(transcript)|ensembl:ENST00000469379(transcript)|ensembl:ENST00000570440(transcript)|interpro:IPR023259|refseq:XP_016878660.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:HUt/KT9UU1L6GNhLjdivX4Qn5yo9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8N3C7 intact:EBI-6377335 intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594 psi-mi:p27958-pro_0000037566(display_long) psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q12894 intact:EBI-6377335 intact:EBI-2512448|ensembl:ENSP00000402849|intact:EBI-6115935|uniprotkb:Q9BVB4|uniprotkb:Q9UJ88 psi-mi:p27958-pro_0000037566(display_long) psi-mi:ifrd2_human(display_long)|uniprotkb:Protein SKMC15(gene name synonym)|uniprotkb:IFRD2(gene name)|psi-mi:IFRD2(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000214706(gene)|ensembl:ENST00000417626(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR006921(Interferon-related protein conserved region)|interpro:IPR007701(Interferon-related developmental regulator)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039777|refseq:NP_006755.4 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:ktxpbUgNcw2DWOJw8o1R4s+U3a09606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9UMY1 intact:EBI-6377335 intact:EBI-2862609|uniprotkb:Q9Y3U7|uniprotkb:Q5T297|ensembl:ENSP00000405674 psi-mi:p27958-pro_0000037566(display_long) psi-mi:nol7_human(display_long)|uniprotkb:NOL7(gene name)|psi-mi:NOL7(display_short)|uniprotkb:C6orf90(gene name synonym)|uniprotkb:NOP27(gene name synonym)|uniprotkb:Nucleolar protein of 27 kDa(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_057251.2|refseq:NP_001304653.1|ensembl:ENSG00000225921(gene)|ensembl:ENST00000451315(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|interpro:IPR012579(NUC129)|interpro:IPR039626|mint:Q9UMY1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:4I1C2wd0qGg9CWZDodm/Bp+tptA9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9H4G4 intact:EBI-6377335 intact:EBI-8787509|uniprotkb:Q5VZR1|uniprotkb:Q8N2S6|uniprotkb:Q8WWC9|uniprotkb:Q8WX36|ensembl:ENSP00000367196 psi-mi:p27958-pro_0000037566(display_long) psi-mi:gapr1_human(display_long)|uniprotkb:GLIPR2(gene name)|psi-mi:GLIPR2(display_short)|uniprotkb:C9orf19(gene name synonym)|uniprotkb:GAPR1(gene name synonym)|uniprotkb:Glioma pathogenesis-related protein 2(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_071738.1|go:"GO:0005615"(extracellular space)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR001283(Allergen V5/Tpx-1 related)|interpro:IPR014044(SCP-like extracellular)|interpro:IPR018244|interpro:IPR034113|interpro:IPR035940|rcsb pdb:1SMB|rcsb pdb:4AIW|rcsb pdb:5VHG|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000122694(gene)|ensembl:ENST00000377960(transcript)|dip:DIP-60127N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:u0wwfyS3oPa1OMxmusk2FGtcnGk9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8IV56 intact:EBI-6377335 intact:EBI-8787485|ensembl:ENSP00000317836 psi-mi:p27958-pro_0000037566(display_long) psi-mi:prr15_human(display_long)|uniprotkb:PRR15(gene name)|psi-mi:PRR15(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:XP_011513500.1|refseq:XP_011513501.1|refseq:NP_787083.1|refseq:NP_001316925.1|refseq:NP_001316926.1|ensembl:ENSG00000176532(gene)|ensembl:ENST00000319694(transcript)|interpro:IPR028237 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:t+jer5Jqsm3x1coFVVgN0A35QGk9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q96EH5 intact:EBI-6377335 intact:EBI-6658607|ensembl:ENSP00000296277|ensembl:ENSP00000389356|ensembl:ENSP00000397240|uniprotkb:Q8IUD0 psi-mi:p27958-pro_0000037566(display_long) psi-mi:rl39l_human(display_long)|uniprotkb:RPL39L(gene name)|psi-mi:RPL39L(display_short)|uniprotkb:60S ribosomal protein L39-2(gene name synonym)|uniprotkb:RPL39L1(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL39-like(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000163923(gene)|ensembl:ENST00000296277(transcript)|ensembl:ENST00000433055(transcript)|ensembl:ENST00000455270(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_443201.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:+tBjkDuXtbj3Tef5dNGi+1mBCVk9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9NU19 intact:EBI-6377335 intact:EBI-8787464|uniprotkb:Q32MQ8|uniprotkb:Q5VUK9|uniprotkb:Q7Z6P7|uniprotkb:Q9BPV6|uniprotkb:Q9BUT5|uniprotkb:Q9NXB6|uniprotkb:A8KA28|uniprotkb:Q6P4C3|ensembl:ENSP00000362590 psi-mi:p27958-pro_0000037566(display_long) psi-mi:tb22b_human(display_long)|uniprotkb:TBC1D22B(gene name)|psi-mi:TBC1D22B(display_short)|uniprotkb:C6orf197(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_060242.2|ensembl:ENSG00000065491(gene)|ensembl:ENST00000373491(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:6D0S - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:7HsT3sqT4dWazVEhXGfOz2fcau09606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9Y5B9 intact:EBI-6377335 intact:EBI-1046849|uniprotkb:Q6GMT8|uniprotkb:Q6P2F1|uniprotkb:Q6PJM1|uniprotkb:Q9NRX0|ensembl:ENSP00000216297 psi-mi:p27958-pro_0000037566(display_long) psi-mi:sp16h_human(display_long)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:SUPT16H(gene name)|psi-mi:SUPT16H(display_short)|uniprotkb:FACT140(gene name synonym)|uniprotkb:FACTP140(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000092201(gene)|ensembl:ENST00000216297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|mint:Q9Y5B9|rcsb pdb:4Z2M|rcsb pdb:4Z2N|rcsb pdb:5E5B|rcsb pdb:5UMT|rcsb pdb:5UMU|rcsb pdb:5XM2|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|refseq:NP_009123.1|dip:DIP-42757N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:jLK5dOF3mEyI0UbZhcNgtdlG+WI9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q16763 intact:EBI-6377335 intact:EBI-2339823|uniprotkb:Q9BTC1|ensembl:ENSP00000264552 psi-mi:p27958-pro_0000037566(display_long) psi-mi:ube2s_human(display_long)|uniprotkb:UBE2S(gene name)|psi-mi:UBE2S(display_short)|uniprotkb:E2EPF(gene name synonym)|uniprotkb:Ubiquitin-protein ligase S(gene name synonym)|uniprotkb:Ubiquitin carrier protein S(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-EPF5(gene name synonym)|uniprotkb:OK/SW-cl.73(orf name)|uniprotkb:E2-EPF(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme S(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_055316.2|dip:DIP-52784N|ensembl:ENSG00000108106(gene)|ensembl:ENST00000264552(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1ZDN|rcsb pdb:5BNB|rcsb pdb:5L9T|rcsb pdb:6QH3|rcsb pdb:6QHK|rcsb pdb:6S96|rcsb pdb:6S98|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-9687136|reactome:R-HSA-983168 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:PiLqBXIHRM8f6hlUXU6PkI3xNtM9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P01112 intact:EBI-6377335 intact:EBI-350145|uniprotkb:Q9BR65|uniprotkb:Q14080|uniprotkb:Q6FHV9|uniprotkb:B5BUA0|uniprotkb:Q9UCE2|ensembl:ENSP00000309845|ensembl:ENSP00000380723|ensembl:ENSP00000407586|ensembl:ENSP00000480686|ensembl:ENSP00000482366|ensembl:ENSP00000488757 psi-mi:p27958-pro_0000037566(display_long) psi-mi:rash_human(display_long)|uniprotkb:HRAS(gene name)|psi-mi:HRAS(display_short)|uniprotkb:HRAS1(gene name synonym)|uniprotkb:Transforming protein p21(gene name synonym)|uniprotkb:p21ras(gene name synonym)|uniprotkb:H-Ras-1(gene name synonym)|uniprotkb:c-H-ras(gene name synonym)|uniprotkb:Ha-Ras(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001123914.1|refseq:NP_005334.1|refseq:NP_789765.1|ensembl:ENSG00000174775(gene)|ensembl:ENSG00000276536(gene)|ensembl:ENST00000311189(transcript)|ensembl:ENST00000397596(transcript)|ensembl:ENST00000451590(transcript)|ensembl:ENST00000610977(transcript)|ensembl:ENST00000615062(transcript)|ensembl:ENST00000631404(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0019003"(GDP binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090398"(cellular senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:P01112|rcsb pdb:121P|rcsb pdb:1AA9|rcsb pdb:1AGP|rcsb pdb:1BKD|rcsb pdb:1CLU|rcsb pdb:1CRP|rcsb pdb:1CRQ|rcsb pdb:1CRR|rcsb pdb:1CTQ|rcsb pdb:1GNP|rcsb pdb:1GNQ|rcsb pdb:1GNR|rcsb pdb:1HE8|rcsb pdb:1IAQ|rcsb pdb:1IOZ|rcsb pdb:1JAH|rcsb pdb:1JAI|rcsb pdb:1K8R|rcsb pdb:1LF0|rcsb pdb:1LF5|rcsb pdb:1LFD|rcsb pdb:1NVU|rcsb pdb:1NVV|rcsb pdb:1NVW|rcsb pdb:1NVX|rcsb pdb:1P2S|rcsb pdb:1P2T|rcsb pdb:1P2U|rcsb pdb:1P2V|rcsb pdb:1PLJ|rcsb pdb:1PLK|rcsb pdb:1PLL|rcsb pdb:1Q21|rcsb pdb:1QRA|rcsb pdb:1RVD|rcsb pdb:1WQ1|rcsb pdb:1XCM|rcsb pdb:1XD2|rcsb pdb:1XJ0|rcsb pdb:1ZVQ|rcsb pdb:1ZW6|rcsb pdb:221P|rcsb pdb:2C5L|rcsb pdb:2CE2|rcsb pdb:2CL0|rcsb pdb:2CL6|rcsb pdb:2CL7|rcsb pdb:2CLC|rcsb pdb:2CLD|rcsb pdb:2EVW|rcsb pdb:2GDP|rcsb pdb:2LCF|rcsb pdb:2LWI|rcsb pdb:2N42|rcsb pdb:2N46|rcsb pdb:2Q21|rcsb pdb:2QUZ|rcsb pdb:2RGA|rcsb pdb:2RGB|rcsb pdb:2RGC|rcsb pdb:2RGD|rcsb pdb:2RGE|rcsb pdb:2RGG|rcsb pdb:2UZI|rcsb pdb:2VH5|rcsb pdb:2X1V|rcsb pdb:3DDC|rcsb pdb:3I3S|rcsb pdb:3K8Y|rcsb pdb:3K9L|rcsb pdb:3K9N|rcsb pdb:3KKM|rcsb pdb:3KKN|rcsb pdb:3KUD|rcsb pdb:3L8Y|rcsb pdb:3L8Z|rcsb pdb:3LBH|rcsb pdb:3LBI|rcsb pdb:3LBN|rcsb pdb:3LO5|rcsb pdb:3OIU|rcsb pdb:3OIV|rcsb pdb:3OIW|rcsb pdb:3RRY|rcsb pdb:3RRZ|rcsb pdb:3RS0|rcsb pdb:3RS2|rcsb pdb:3RS3|rcsb pdb:3RS4|rcsb pdb:3RS5|rcsb pdb:3RS7|rcsb pdb:3RSL|rcsb pdb:3RSO|rcsb pdb:3TGP|rcsb pdb:421P|rcsb pdb:4DLR|rcsb pdb:4DLS|rcsb pdb:4DLT|rcsb pdb:4DLU|rcsb pdb:4DLV|rcsb pdb:4DLW|rcsb pdb:4DLX|rcsb pdb:4DLY|rcsb pdb:4DLZ|rcsb pdb:4DST|rcsb pdb:4DSU|rcsb pdb:4EFL|rcsb pdb:4EFM|rcsb pdb:4EFN|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4K81|rcsb pdb:4L9S|rcsb pdb:4L9W|rcsb pdb:4NYI|rcsb pdb:4NYJ|rcsb pdb:4NYM|rcsb pdb:4Q21|rcsb pdb:4RSG|rcsb pdb:4URU|rcsb pdb:4URV|rcsb pdb:4URW|rcsb pdb:4URX|rcsb pdb:4URY|rcsb pdb:4URZ|rcsb pdb:4US0|rcsb pdb:4US1|rcsb pdb:4US2|rcsb pdb:4XVQ|rcsb pdb:4XVR|rcsb pdb:521P|rcsb pdb:5B2Z|rcsb pdb:5B30|rcsb pdb:5E95|rcsb pdb:5P21|rcsb pdb:5VBE|rcsb pdb:5VBZ|rcsb pdb:5WDO|rcsb pdb:5WDP|rcsb pdb:5WDQ|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2871796|reactome:R-HSA-375165|reactome:R-HSA-3928662|reactome:R-HSA-442982|reactome:R-HSA-5218921|reactome:R-HSA-5621575|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5658442|reactome:R-HSA-5673000|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6Q21|rcsb pdb:5WFO|rcsb pdb:5WFP|rcsb pdb:5WFQ|rcsb pdb:5WFR|rcsb pdb:5WPL|rcsb pdb:5X9S|rcsb pdb:5ZC6|rcsb pdb:6V94|rcsb pdb:6V9F|rcsb pdb:6V9J|rcsb pdb:6V9L|rcsb pdb:6V9M|rcsb pdb:621P|rcsb pdb:6AMB|rcsb pdb:6AXG|rcsb pdb:6BVI|rcsb pdb:6BVJ|rcsb pdb:6BVK|rcsb pdb:6BVL|rcsb pdb:6BVM|rcsb pdb:6CUO|rcsb pdb:6CUP|rcsb pdb:6CUR|rcsb pdb:6D55|rcsb pdb:6D56|rcsb pdb:6D59|rcsb pdb:6D5E|rcsb pdb:6D5G|rcsb pdb:6D5H|rcsb pdb:6D5J|rcsb pdb:6D5L|rcsb pdb:6D5M|rcsb pdb:6D5V|rcsb pdb:6D5W|rcsb pdb:6DZH|rcsb pdb:6E6C|rcsb pdb:6E6P|rcsb pdb:6MQT|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802953|reactome:R-HSA-6802955|reactome:R-HSA-74751|reactome:R-HSA-8849471|reactome:R-HSA-8851805|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9634635|reactome:R-HSA-9648002|reactome:R-HSA-9649913|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9703465|reactome:R-HSA-9703648|rcsb pdb:6V9N|rcsb pdb:6V9O|rcsb pdb:6ZJ0|rcsb pdb:6ZL3|rcsb pdb:721P|rcsb pdb:7JHP|rcsb pdb:7L0F|rcsb pdb:7L0G|rcsb pdb:821P|reactome:R-HSA-112412|reactome:R-HSA-1169092|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-167044|reactome:R-HSA-171007|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-210993|refseq:NP_001304983.1|dip:DIP-1050N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:hjBAnRVG6bLFePkCYnkl3ZCjnmw9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q6B0I6 intact:EBI-6377335 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 psi-mi:p27958-pro_0000037566(display_long) psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P06746 intact:EBI-6377335 intact:EBI-713836|ensembl:ENSP00000265421|uniprotkb:Q3KP48|uniprotkb:Q6FI34|uniprotkb:B2RC78 psi-mi:p27958-pro_0000037566(display_long) psi-mi:dpolb_human(display_long)|uniprotkb:POLB(gene name)|psi-mi:POLB(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000070501(gene)|refseq:NP_002681.1|rcsb pdb:4F5Q|rcsb pdb:4F5R|rcsb pdb:4GXI|rcsb pdb:4GXJ|rcsb pdb:4GXK|rcsb pdb:4JWM|rcsb pdb:4JWN|rcsb pdb:4KLD|rcsb pdb:4KLE|rcsb pdb:4KLF|rcsb pdb:4KLG|rcsb pdb:4KLH|rcsb pdb:4KLI|rcsb pdb:4KLJ|rcsb pdb:4KLL|rcsb pdb:4KLM|rcsb pdb:4F5P|rcsb pdb:4KLO|rcsb pdb:4KLQ|rcsb pdb:4KLS|rcsb pdb:4KLT|rcsb pdb:4KLU|rcsb pdb:4LVS|rcsb pdb:5DB9|rcsb pdb:5DBA|rcsb pdb:5DBB|rcsb pdb:5DBC|rcsb pdb:5EOZ|rcsb pdb:5HHH|rcsb pdb:5HHI|rcsb pdb:5J0O|rcsb pdb:5J0P|rcsb pdb:5J0Q|rcsb pdb:5J0R|rcsb pdb:5J0S|rcsb pdb:5J0T|rcsb pdb:5J0U|rcsb pdb:5J0W|rcsb pdb:5J0X|rcsb pdb:5J0Y|rcsb pdb:5J29|rcsb pdb:5J2A|rcsb pdb:5J2B|rcsb pdb:5J2C|rcsb pdb:5J2D|rcsb pdb:5J2E|rcsb pdb:5J2F|rcsb pdb:5J2G|rcsb pdb:5J2H|rcsb pdb:5J2I|rcsb pdb:5J2J|rcsb pdb:5J2K|rcsb pdb:5TB8|rcsb pdb:5TB9|rcsb pdb:5TBA|rcsb pdb:5TBB|rcsb pdb:4M2Y|rcsb pdb:4YMM|rcsb pdb:5TBC|rcsb pdb:5TZV|rcsb pdb:5U2R|rcsb pdb:5U2S|rcsb pdb:4YMN|rcsb pdb:4YMO|rcsb pdb:4YN4|rcsb pdb:4Z6C|rcsb pdb:5U2T|rcsb pdb:5U8G|rcsb pdb:5U8H|rcsb pdb:4Z6D|rcsb pdb:4Z6E|rcsb pdb:4Z6F|rcsb pdb:5BOL|rcsb pdb:5BOM|rcsb pdb:5BPC|rcsb pdb:5DB6|rcsb pdb:5DB7|rcsb pdb:5DB8|rcsb pdb:5U8I|rcsb pdb:5U9H|rcsb pdb:5UGN|rcsb pdb:6CTR|rcsb pdb:6CTT|rcsb pdb:6CTU|rcsb pdb:6CTV|rcsb pdb:6CTW|rcsb pdb:6CTX|rcsb pdb:6CU9|rcsb pdb:6CUA|rcsb pdb:6CUB|rcsb pdb:6DIA|rcsb pdb:6DIC|rcsb pdb:6E3R|rcsb pdb:6E3V|rcsb pdb:6CTQ|rcsb pdb:6E3W|rcsb pdb:6E3X|rcsb pdb:6G2Q|rcsb pdb:6MR7|rcsb pdb:6MR8|rcsb pdb:6N2R|rcsb pdb:6N2S|rcsb pdb:6N2T|rcsb pdb:6NKR|rcsb pdb:6NKS|rcsb pdb:6NKT|rcsb pdb:6NKU|rcsb pdb:6NKV|rcsb pdb:6NKW|rcsb pdb:6NKX|rcsb pdb:6NKY|rcsb pdb:6NKZ|rcsb pdb:6NL0|rcsb pdb:6PH5|rcsb pdb:6PH6|rcsb pdb:6PKZ|rcsb pdb:6U2O|rcsb pdb:6U6B|rcsb pdb:4M9G|rcsb pdb:4M9H|rcsb pdb:4M9J|rcsb pdb:4M9L|rcsb pdb:4M9N|rcsb pdb:4MF2|rcsb pdb:4MF8|rcsb pdb:4MFA|rcsb pdb:4MFC|rcsb pdb:4MFF|rcsb pdb:4NLK|rcsb pdb:4NLN|rcsb pdb:4NLZ|rcsb pdb:4NM1|rcsb pdb:4NM2|rcsb pdb:4NXZ|rcsb pdb:4NY8|rcsb pdb:4O5C|rcsb pdb:4O5E|rcsb pdb:4O5K|rcsb pdb:4O9M|rcsb pdb:4P2H|rcsb pdb:4PGQ|rcsb pdb:4PGX|rcsb pdb:4PGY|rcsb pdb:4M47|ensembl:ENST00000265421(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006286"(obsolete base-excision repair, base-free sugar-phosphate removal)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007568"(aging)|go:"GO:0008017"(microtubule binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016829"(lyase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|rcsb pdb:5UGP|rcsb pdb:5V1F|rcsb pdb:5V1G|rcsb pdb:5V1H|rcsb pdb:5V1I|rcsb pdb:5V1J|rcsb pdb:5V1N|rcsb pdb:5V1O|rcsb pdb:5V1P|rcsb pdb:5V1R|rcsb pdb:5VEZ|rcsb pdb:5VRW|rcsb pdb:5VRX|rcsb pdb:5VRY|rcsb pdb:5VRZ|rcsb pdb:5VS0|rcsb pdb:5VS1|rcsb pdb:5VS2|rcsb pdb:5VS3|rcsb pdb:5VS4|rcsb pdb:5WNX|rcsb pdb:5WNY|rcsb pdb:5WNZ|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|interpro:IPR002008(DNA-directed DNA polymerase, family X, beta-like)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|interpro:IPR027421|interpro:IPR028207|interpro:IPR029398|interpro:IPR037160|interpro:IPR043519|go:"GO:0032991"(protein-containing complex)|rcsb pdb:1BPX|rcsb pdb:1BPY|rcsb pdb:1BPZ|rcsb pdb:1MQ2|rcsb pdb:1MQ3|rcsb pdb:1TV9|rcsb pdb:1TVA|rcsb pdb:1ZJM|rcsb pdb:1ZJN|rcsb pdb:4PHA|rcsb pdb:4PHD|rcsb pdb:4PHE|rcsb pdb:4PHP|rcsb pdb:4PPX|rcsb pdb:4R63|rcsb pdb:4R64|rcsb pdb:4R65|rcsb pdb:4R66|rcsb pdb:4RPX|rcsb pdb:4RPY|rcsb pdb:4RPZ|rcsb pdb:4RQ0|rcsb pdb:4RQ1|rcsb pdb:4RQ2|rcsb pdb:4RQ3|rcsb pdb:4RQ4|rcsb pdb:4RQ5|rcsb pdb:4RQ6|rcsb pdb:4RQ7|rcsb pdb:4RQ8|rcsb pdb:4RT2|rcsb pdb:4RT3|rcsb pdb:4TUP|rcsb pdb:4TUQ|rcsb pdb:4TUR|rcsb pdb:4TUS|rcsb pdb:4UAW|rcsb pdb:4PH5|rcsb pdb:4UAY|rcsb pdb:4UAZ|rcsb pdb:4UB1|rcsb pdb:4UB2|rcsb pdb:4UB3|rcsb pdb:4UB4|rcsb pdb:4UB5|rcsb pdb:4UBB|rcsb pdb:4UBC|rcsb pdb:1ZQB|rcsb pdb:1ZQC|rcsb pdb:1ZQD|rcsb pdb:1ZQE|rcsb pdb:1ZQF|rcsb pdb:1ZQG|rcsb pdb:1ZQH|rcsb pdb:1ZQI|rcsb pdb:1ZQJ|rcsb pdb:1ZQK|rcsb pdb:1ZQL|rcsb pdb:1ZQM|rcsb pdb:1ZQN|rcsb pdb:1ZQO|rcsb pdb:1ZQP|rcsb pdb:1ZQQ|rcsb pdb:1ZQR|rcsb pdb:1ZQS|rcsb pdb:1ZQA|rcsb pdb:1ZQT|rcsb pdb:2FMP|rcsb pdb:5WO0|rcsb pdb:6BEL|rcsb pdb:6BEM|rcsb pdb:6BTE|rcsb pdb:6BTF|rcsb pdb:6CLY|rcsb pdb:6CPQ|rcsb pdb:6CR3|rcsb pdb:6CR4|rcsb pdb:6CR5|rcsb pdb:6CR6|rcsb pdb:6CR7|rcsb pdb:6CR8|rcsb pdb:6CR9|rcsb pdb:6CRB|rcsb pdb:6CRC|rcsb pdb:6CRH|rcsb pdb:6CTI|rcsb pdb:6CTJ|rcsb pdb:5UGO|rcsb pdb:6CTK|rcsb pdb:6CTL|rcsb pdb:6CTM|rcsb pdb:6CTN|rcsb pdb:6CTO|rcsb pdb:6CTP|rcsb pdb:2FMS|rcsb pdb:2I9G|rcsb pdb:2ISO|rcsb pdb:2ISP|rcsb pdb:2P66|rcsb pdb:2PXI|rcsb pdb:3C2K|rcsb pdb:3C2L|rcsb pdb:3C2M|rcsb pdb:3GDX|rcsb pdb:3ISB|rcsb pdb:3ISC|rcsb pdb:3ISD|rcsb pdb:3JPN|rcsb pdb:3JPO|rcsb pdb:3JPP|rcsb pdb:3JPQ|rcsb pdb:3JPR|rcsb pdb:3JPS|rcsb pdb:3JPT|rcsb pdb:3LK9|rcsb pdb:3MBY|rcsb pdb:3OGU|rcsb pdb:3RH4|rcsb pdb:3RH5|rcsb pdb:3RH6|rcsb pdb:3RJE|rcsb pdb:3RJF|rcsb pdb:3RJG|rcsb pdb:3RJH|rcsb pdb:3RJI|rcsb pdb:3RJJ|rcsb pdb:3RJK|rcsb pdb:3TFR|rcsb pdb:3TFS|rcsb pdb:4DO9|rcsb pdb:2FMQ|rcsb pdb:4DOA|rcsb pdb:4DOB|rcsb pdb:4DOC|rcsb pdb:4F5N|rcsb pdb:4F5O|rcsb pdb:6UOL|rcsb pdb:6UOM|rcsb pdb:6W2M|rcsb pdb:7ICE|rcsb pdb:7ICF|rcsb pdb:7ICG|rcsb pdb:7ICH|rcsb pdb:7ICI|rcsb pdb:7ICJ|rcsb pdb:7ICK|rcsb pdb:7ICL|rcsb pdb:7ICM|rcsb pdb:7ICN|rcsb pdb:7ICO|rcsb pdb:7ICP|rcsb pdb:7ICQ|rcsb pdb:7ICR|rcsb pdb:7ICS|rcsb pdb:7ICT|rcsb pdb:7ICU|rcsb pdb:7ICV|rcsb pdb:7K96|rcsb pdb:7K97|rcsb pdb:8ICA|rcsb pdb:8ICB|rcsb pdb:8ICC|rcsb pdb:8ICE|rcsb pdb:8ICF|rcsb pdb:6UOK|rcsb pdb:8ICG|rcsb pdb:8ICH|rcsb pdb:8ICI|rcsb pdb:8ICJ|rcsb pdb:8ICK|rcsb pdb:8ICL|rcsb pdb:8ICM|rcsb pdb:8ICN|rcsb pdb:8ICO|rcsb pdb:8ICP|rcsb pdb:8ICQ|rcsb pdb:8ICR|rcsb pdb:8ICS|rcsb pdb:8ICT|rcsb pdb:8ICU|rcsb pdb:8ICV|rcsb pdb:8ICW|rcsb pdb:8ICX|rcsb pdb:8ICY|rcsb pdb:8ICZ|rcsb pdb:9ICA|rcsb pdb:9ICB|rcsb pdb:9ICC|rcsb pdb:9ICE|rcsb pdb:9ICF|rcsb pdb:9ICG|rcsb pdb:9ICH|rcsb pdb:9ICI|reactome:R-HSA-5649702|reactome:R-HSA-5651801|reactome:R-HSA-5689880|reactome:R-HSA-73930|rcsb pdb:9ICK|rcsb pdb:9ICL|rcsb pdb:9ICM|rcsb pdb:9ICN|rcsb pdb:9ICO|rcsb pdb:9ICP|rcsb pdb:9ICQ|rcsb pdb:9ICR|rcsb pdb:9ICS|rcsb pdb:9ICT|rcsb pdb:9ICU|rcsb pdb:9ICV|rcsb pdb:9ICW|rcsb pdb:9ICX|rcsb pdb:9ICY|reactome:R-HSA-110362|reactome:R-HSA-110373|rcsb pdb:9ICJ|reactome:R-HSA-110381 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:5HnAwQ3j7XA+ZCsuFjsQWvAZHVY9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8IXJ9 intact:EBI-6377335 intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 psi-mi:p27958-pro_0000037566(display_long) psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway) - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q96DX7 intact:EBI-6377335 intact:EBI-8787399|uniprotkb:D3DR14|uniprotkb:Q96QY2|uniprotkb:Q9UGK0|ensembl:ENSP00000299413 psi-mi:p27958-pro_0000037566(display_long) psi-mi:tri44_human(display_long)|uniprotkb:TRIM44(gene name)|psi-mi:TRIM44(display_short)|uniprotkb:DIPB(gene name synonym)|uniprotkb:Protein DIPB(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_060053.2|ensembl:ENSG00000166326(gene)|ensembl:ENST00000299413(transcript)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061944"(negative regulation of protein K48-linked ubiquitination)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box) - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:Tq9Rf+jwAlZ/okqhFIUwlgC6M7s9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P60002 intact:EBI-6377335 intact:EBI-714648|uniprotkb:Q8R1J7|uniprotkb:Q96II4|ensembl:ENSP00000252445|ensembl:ENSP00000467264|ensembl:ENSP00000467914 psi-mi:p27958-pro_0000037566(display_long) psi-mi:elof1_human(display_long)|uniprotkb:ELOF1(gene name)|psi-mi:ELOF1(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_115753.1|ensembl:ENSG00000130165(gene)|ensembl:ENST00000252445(transcript)|ensembl:ENST00000586120(transcript)|ensembl:ENST00000590700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048096"|interpro:IPR007808(Protein of unknown function DUF701, zinc-binding putative)|interpro:IPR038567|mint:P60002|refseq:XP_016882847.1|refseq:XP_016882848.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:Nz9Znnrr8Y628LTeHgsr6Q05a289606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9Y5P8 intact:EBI-6377335 intact:EBI-2479826|intact:EBI-28984956|ensembl:ENSP00000375080|uniprotkb:Q6P4G9|uniprotkb:Q7RTT1|uniprotkb:Q96H01 psi-mi:p27958-pro_0000037566(display_long) psi-mi:p2r3b_human(display_long)|uniprotkb:PPP2R3B(gene name)|psi-mi:PPP2R3B(display_short)|uniprotkb:PPP2R3L(gene name synonym)|uniprotkb:Protein phosphatase 2A 48 kDa regulatory subunit(gene name synonym)|uniprotkb:PP2A subunit B isoform PR48(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000167393(gene)|ensembl:ENST00000390665(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR041534|mint:Q9Y5P8|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4MEW|reactome:R-HSA-113501|reactome:R-HSA-69231|reactome:R-HSA-69273|go:"GO:0005654"(nucleoplasm)|refseq:NP_037371.2|ensembl:ENSP00000375080 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:zl5NREjuW2ahdojQSDcqWYJR92g9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:O43852 intact:EBI-6377335 intact:EBI-1171069|uniprotkb:O60456|uniprotkb:Q6FHB9|uniprotkb:Q96RL3|uniprotkb:Q9NR43|intact:EBI-2554631|uniprotkb:B3KPG9|uniprotkb:D6QS48|uniprotkb:D6QS49|uniprotkb:D6QS50|uniprotkb:D6QS51|uniprotkb:D6QS52|uniprotkb:D6QS53|uniprotkb:D6QS54|uniprotkb:D6QS55|uniprotkb:D6QS56|uniprotkb:D6QS57|uniprotkb:D6QS58|uniprotkb:D6QS59|uniprotkb:F5H1Q9|uniprotkb:F5H879|ensembl:ENSP00000249364 psi-mi:p27958-pro_0000037566(display_long) psi-mi:calu_human(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001124146.1|refseq:NP_001186602.1|refseq:NP_001210.1|refseq:NP_001186600.1|refseq:NP_001186601.1|ensembl:ENSG00000128595(gene)|ensembl:ENST00000249364(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O43852|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:XP_016868148.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:lgl1dEYzu+XFHq3QJ/w69xg51Ts9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9UHV2 intact:EBI-6377335 intact:EBI-748601|uniprotkb:Q9BUE7|ensembl:ENSP00000350633 psi-mi:p27958-pro_0000037566(display_long) psi-mi:srtd1_human(display_long)|uniprotkb:Transcriptional regulator interacting with the PHD-bromodomain 1(gene name synonym)|uniprotkb:CDK4-binding protein p34SEI1(gene name synonym)|uniprotkb:SERTAD1(gene name)|psi-mi:SERTAD1(display_short)|uniprotkb:SEI1(gene name synonym)|uniprotkb:TRIPBR1(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_037508.2|ensembl:ENSG00000197019(gene)|ensembl:ENST00000357949(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|interpro:IPR009263(SERTA)|mint:Q9UHV2 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:40dvjniwxY/UQiyoVREicctpWe09606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q5MJ08 intact:EBI-6377335 intact:EBI-6660231|ensembl:ENSP00000405210|uniprotkb:Q5W0S6|uniprotkb:Q0ZNK6 psi-mi:p27958-pro_0000037566(display_long) psi-mi:spxn4_human(display_long)|uniprotkb:SPANXN4(gene name)|psi-mi:SPANXN4(display_short)|uniprotkb:Nuclear-associated protein SPAN-Xn4(gene name synonym)|uniprotkb:SPANX family member N4(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000189326(gene)|ensembl:ENST00000446864(transcript)|interpro:IPR010007(Sperm associated with nucleus, X chromosome)|refseq:NP_001009613.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:T6tgJ5NA6gAFp+ZXcaE0wKYZxoE9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8N6M0 intact:EBI-6377335 intact:EBI-2510892|ensembl:ENSP00000384190|uniprotkb:B4DEY0|uniprotkb:Q9Y387|uniprotkb:A8K6I1|uniprotkb:Q9NTA4 psi-mi:p27958-pro_0000037566(display_long) psi-mi:otu6b_human(display_long)|uniprotkb:OTUD6B(gene name)|psi-mi:OTUD6B(display_short)|uniprotkb:DUBA5(gene name synonym)|uniprotkb:DUBA-5(gene name synonym)|uniprotkb:OTU domain-containing protein 6B(gene name synonym)|uniprotkb:CGI-77(orf name) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000155100(gene)|ensembl:ENST00000404789(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0043248"(proteasome assembly)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR038765|refseq:NP_057107.3|refseq:XP_011515431.2|refseq:NP_001273674.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:04LzUJC/KXoSlb5LaciuO+9Sw+U9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q68E01 intact:EBI-6377335 intact:EBI-2680854|uniprotkb:Q8TB23|uniprotkb:Q6MZQ4|uniprotkb:Q9H6S9|uniprotkb:Q6AI57|uniprotkb:Q5VUQ6|uniprotkb:Q4G0E5|uniprotkb:B4DQC8|uniprotkb:B4E3U9|uniprotkb:A8K1W0|uniprotkb:Q8NC46|uniprotkb:Q68DJ1|uniprotkb:Q6DKG7|uniprotkb:Q5VUR1|uniprotkb:Q6MZZ9|uniprotkb:Q5VUQ5|uniprotkb:Q69YR5|uniprotkb:Q5VUR0|uniprotkb:D3DV57 psi-mi:p27958-pro_0000037566(display_long) psi-mi:int3_human(display_long)|uniprotkb:INTS3(gene name)|psi-mi:INTS3(display_short)|uniprotkb:C1orf193(gene name synonym)|uniprotkb:C1orf60(gene name synonym)|uniprotkb:SOSS complex subunit A(gene name synonym)|uniprotkb:Sensor of single-strand DNA complex subunit A(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_075391.3|interpro:IPR019333|refseq:XP_005245518.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0070876"(SOSS complex)|rcsb pdb:4OWT|rcsb pdb:4OWW|rcsb pdb:4OWX|rcsb pdb:6WLG|reactome:R-HSA-6807505|refseq:NP_001311404.1|mint:Q68E01 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:GxQTTVSOwBdWifr7ZdM8Zbqxy5M9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P11137 intact:EBI-6377335 intact:EBI-2682460|uniprotkb:Q17S04|uniprotkb:Q99975|uniprotkb:Q99976|uniprotkb:Q8IUX2|ensembl:ENSP00000353508|ensembl:ENSP00000507035 psi-mi:p27958-pro_0000037566(display_long) psi-mi:mtap2_human(display_long)|uniprotkb:MAP2(gene name)|psi-mi:MAP2(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_002365.3|refseq:NP_114033.2|refseq:NP_114035.2|refseq:NP_001034627.1|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1903744"(positive regulation of anterograde synaptic vesicle transport)|go:"GO:1903827"|go:"GO:1904527"(negative regulation of microtubule binding)|go:"GO:1990635"(proximal dendrite)|go:"GO:1990769"(proximal neuron projection)|go:"GO:2000575"(obsolete negative regulation of microtubule motor activity)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR013588(MAP2/Tau projection)|interpro:IPR030797|mint:P11137|ensembl:ENSG00000078018(gene)|ensembl:ENST00000360351(transcript)|ensembl:ENST00000682079(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0008017"(microtubule binding)|go:"GO:0016358"(dendrite development)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030425"(dendrite)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043203"(axon hillock)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044307"(dendritic branch)|go:"GO:0048156"(tau protein binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0097441"(basal dendrite)|go:"GO:0150001"(primary dendrite)|go:"GO:0150002"(distal dendrite)|go:"GO:0150014"(apical distal dendrite)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|refseq:XP_016859607.1|refseq:XP_016859612.1|refseq:XP_016859613.1|refseq:XP_016859627.1|refseq:XP_016859628.1|dip:DIP-577N|refseq:XP_016859629.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:IfbwC7748mUgLEmuxR5Zd2TEQ/09606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8WWL7 intact:EBI-6377335 intact:EBI-767764|uniprotkb:Q96SB5|uniprotkb:Q96SB6|uniprotkb:Q96SB7|uniprotkb:Q9NT38|uniprotkb:B1AQI6|uniprotkb:B1AQI5|ensembl:ENSP00000365210|ensembl:ENSP00000276014 psi-mi:p27958-pro_0000037566(display_long) psi-mi:ccnb3_human(display_long)|uniprotkb:CCNB3(gene name)|psi-mi:CCNB3(display_short)|uniprotkb:CYCB3(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_149020.2|refseq:NP_391990.1|refseq:XP_016885407.1|ensembl:ENSG00000147082(gene)|ensembl:ENST00000276014(transcript)|ensembl:ENST00000376042(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015452(G2/mitotic-specific cyclin B3)|interpro:IPR036915|interpro:IPR039361|mint:Q8WWL7 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:DWq1aIaKl0+TykoAniMvm2EXdmY9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:O75937 intact:EBI-6377335 intact:EBI-1045911|uniprotkb:Q6IBA4|uniprotkb:Q8N4Z5|uniprotkb:Q9P051|uniprotkb:Q9P067|uniprotkb:D3DPM0|uniprotkb:B4DUU4|intact:EBI-28966785|ensembl:ENSP00000263697|ensembl:ENSP00000494062 psi-mi:p27958-pro_0000037566(display_long) psi-mi:dnjc8_human(display_long)|uniprotkb:Splicing protein spf31(gene name synonym)|uniprotkb:DNAJC8(gene name)|psi-mi:DNAJC8(display_short)|uniprotkb:SPF31(gene name synonym)|uniprotkb:HSPC315(orf name)|uniprotkb:HSPC331(orf name) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSP00000263697|ensembl:ENSP00000494062|ensembl:ENSG00000126698(gene)|ensembl:ENSG00000285317(gene)|ensembl:ENST00000263697(transcript)|ensembl:ENST00000645856(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0045171"(intercellular bridge)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869|interpro:IPR042858|mint:O75937|reactome:R-HSA-72163|refseq:NP_055095.2 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:muJkeaOMc4UXHR4DPNuQeciq7PI9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9Y3T9 intact:EBI-6377335 intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992 psi-mi:p27958-pro_0000037566(display_long) psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:O15205 intact:EBI-6377335 intact:EBI-6657186|ensembl:ENSP00000366249|ensembl:ENSP00000373039|ensembl:ENSP00000396152|ensembl:ENSP00000410416|uniprotkb:Q96EC7|uniprotkb:Q5STL2|uniprotkb:B0UZT6|uniprotkb:Q5SUK2 psi-mi:p27958-pro_0000037566(display_long) psi-mi:ubd_human(display_long)|uniprotkb:UBD(gene name)|psi-mi:UBD(display_short)|uniprotkb:Diubiquitin(gene name synonym)|uniprotkb:FAT10(gene name synonym)|uniprotkb:Ubiquitin-like protein FAT10(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000231968(gene)|ensembl:ENST00000377050(transcript)|ensembl:ENST00000383547(transcript)|ensembl:ENST00000421519(transcript)|ensembl:ENST00000432676(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|ensembl:ENSG00000206468(gene)|ensembl:ENSG00000213886(gene)|ensembl:ENSG00000228913(gene)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0070628"(proteasome binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR000626(Ubiquitin)|interpro:IPR019956|interpro:IPR029071|interpro:IPR042969|rcsb pdb:2MBE|rcsb pdb:6GF1|rcsb pdb:6GF2|reactome:R-HSA-8951664|refseq:NP_006389.2 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:ySUgohBHmcPaAaD/l21zkQ3+MPI9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P61328 intact:EBI-6377335 intact:EBI-6657662|ensembl:ENSP00000413496|uniprotkb:Q93001|uniprotkb:B2R6B7|uniprotkb:O35339|uniprotkb:Q8TBG5|uniprotkb:P70376|uniprotkb:B2R976|uniprotkb:Q92912 psi-mi:p27958-pro_0000037566(display_long) psi-mi:fgf12_human(display_long)|uniprotkb:FGF12(gene name)|psi-mi:FGF12(display_short)|uniprotkb:FGF12B(gene name synonym)|uniprotkb:FHF1(gene name synonym)|uniprotkb:Fibroblast growth factor homologous factor 1(gene name synonym)|uniprotkb:Myocyte-activating factor(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000114279(gene)|ensembl:ENST00000454309(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008083"(growth factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0008201"(heparin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0007165"(signal transduction)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0050905"(neuromuscular process)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:2001258"(negative regulation of cation channel activity)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|go:"GO:0007254"(JNK cascade)|go:"GO:0007267"(cell-cell signaling)|interpro:IPR028254|rcsb pdb:1Q1U|rcsb pdb:4JQ0|reactome:R-HSA-5576892|refseq:NP_004104.3|refseq:NP_066360.1|dip:DIP-59850N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:o0b68lEx/K68wlcJP22mQgf5VJs9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P55036 intact:EBI-6377335 intact:EBI-359318|uniprotkb:Q5VWC5|uniprotkb:Q9NS92|uniprotkb:D3DV16|ensembl:ENSP00000357879 psi-mi:p27958-pro_0000037566(display_long) psi-mi:psmd4_human(display_long)|uniprotkb:PSMD4(gene name)|psi-mi:PSMD4(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:Antisecretory factor 1(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_002801.1|dip:DIP-38189N|ensembl:ENSG00000159352(gene)|ensembl:ENST00000368884(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|mint:P55036|rcsb pdb:1P9C|rcsb pdb:1P9D|rcsb pdb:1UEL|rcsb pdb:1YX4|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:2KDE|rcsb pdb:2KDF|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6MUN|rcsb pdb:6U19|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:FTJG3ns3Ag/Y3xP3yEydGxppRcA9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:O14576 intact:EBI-6377335 intact:EBI-366267|uniprotkb:Q9Y2X1|intact:EBI-747976|uniprotkb:B4DME3|uniprotkb:F5H050|uniprotkb:G5E9K1|uniprotkb:Q8TBF7|ensembl:ENSP00000320130 psi-mi:p27958-pro_0000037566(display_long) psi-mi:dc1i1_human(display_long)|uniprotkb:DYNC1I1(gene name)|psi-mi:DYNC1I1(display_short)|uniprotkb:DNCIC1(gene name synonym)|uniprotkb:Cytoplasmic dynein intermediate chain 1(gene name synonym)|uniprotkb:Dynein intermediate chain 1, cytosolic(gene name synonym)|uniprotkb:DNCI1(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001129028.1|refseq:NP_001129029.1|refseq:NP_004402.1|refseq:XP_011514163.1|refseq:XP_011514164.1|refseq:NP_001265350.1|refseq:NP_001265351.1|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR025956|interpro:IPR036322|mint:O14576|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-2500257|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-3371497|ensembl:ENSG00000158560(gene)|ensembl:ENST00000324972(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|refseq:XP_016867293.1|refseq:XP_016867294.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:Hw0CFWl7NZ1lMObYmGYYcH+J1Xw9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9Y3E1 intact:EBI-6377335 intact:EBI-2847459|ensembl:ENSP00000299633 psi-mi:p27958-pro_0000037566(display_long) psi-mi:hdgr3_human(display_long)|uniprotkb:HDGFRP3(gene name synonym)|uniprotkb:Hepatoma-derived growth factor 2(gene name synonym)|uniprotkb:CGI-142(orf name)|uniprotkb:HDGF2(gene name synonym)|uniprotkb:HDGFL3(gene name)|psi-mi:HDGFL3(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_057157.1|rcsb pdb:6IIT|ensembl:ENSG00000166503(gene)|ensembl:ENST00000299633(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008083"(growth factor activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0046785"(microtubule polymerization)|interpro:IPR000313(PWWP)|interpro:IPR035496|rcsb pdb:6IIP|rcsb pdb:6IIQ|rcsb pdb:6IIR|rcsb pdb:6IIS - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:Vnro7b4zspbAY5CfYOzvb9et17s9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q13442 intact:EBI-6377335 intact:EBI-1390763|uniprotkb:Q92906|uniprotkb:D6W5S5|ensembl:ENSP00000222968 psi-mi:p27958-pro_0000037566(display_long) psi-mi:hap28_human(display_long)|uniprotkb:PDGF-associated protein(gene name synonym)|uniprotkb:PDGFA-associated protein 1(gene name synonym)|uniprotkb:PDAP1(gene name)|psi-mi:PDAP1(display_short)|uniprotkb:HASPP28(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_055706.1|ensembl:ENSG00000106244(gene)|ensembl:ENST00000350498(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019380|interpro:IPR039876|mint:Q13442|reactome:R-HSA-6798695 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:8oY/0PM5kBr34vOdRXuGjIVFMgU9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9HCS5 intact:EBI-6377335 intact:EBI-6658938|ensembl:ENSP00000261486|uniprotkb:A4FUI6 psi-mi:p27958-pro_0000037566(display_long) psi-mi:e41la_human(display_long)|uniprotkb:EPB41L4A(gene name)|psi-mi:EPB41L4A(display_short)|uniprotkb:EPB41L4(gene name synonym)|uniprotkb:Protein NBL4(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 4A(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001334816.1|refseq:NP_071423.4|ensembl:ENSG00000129595(gene)|ensembl:ENST00000261486(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0031032"(actomyosin structure organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030696|interpro:IPR035963 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:iCdZzwSIn4ZxlND25SHcIxag2Zk9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q96CN9 intact:EBI-6377335 intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821 psi-mi:p27958-pro_0000037566(display_long) psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna) - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P51959 intact:EBI-6377335 intact:EBI-3905829|uniprotkb:B4DLW7|uniprotkb:Q96L32|uniprotkb:B2R7B2|uniprotkb:D3DQK7|uniprotkb:Q15757|ensembl:ENSP00000344635|ensembl:ENSP00000377506 psi-mi:p27958-pro_0000037566(display_long) psi-mi:ccng1_human(display_long)|uniprotkb:CCNG1(gene name)|psi-mi:CCNG1(display_short)|uniprotkb:CCNG(gene name synonym)|uniprotkb:CYCG1(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_004051.1|refseq:NP_954854.1|ensembl:ENSG00000113328(gene)|ensembl:ENST00000340828(transcript)|ensembl:ENST00000393929(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028860|interpro:IPR036915|interpro:IPR039361|mint:P51959|reactome:R-HSA-6804757 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:DhgfMSyS+eZKcwarhgM5tYthdLg9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q08426 intact:EBI-6377335 intact:EBI-2339219|uniprotkb:Q58EZ5|uniprotkb:A8K6Y3|uniprotkb:B4DWG3|uniprotkb:D3DNU0|ensembl:ENSP00000231887 psi-mi:p27958-pro_0000037566(display_long) psi-mi:echp_human(display_long)|uniprotkb:EHHADH(gene name)|psi-mi:EHHADH(display_short)|uniprotkb:ECHD(gene name synonym)|uniprotkb:L-bifunctional protein(gene name synonym)|uniprotkb:Multifunctional enzyme 1(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001159887.1|refseq:NP_001957.2|refseq:XP_011510819.1|ensembl:ENSG00000113790(gene)|ensembl:ENST00000231887(transcript)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0016863"(intramolecular oxidoreductase activity, transposing C=C bonds)|go:"GO:0019899"(enzyme binding)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|reactome:R-HSA-390247|reactome:R-HSA-9033241 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:wLWtQcRIDop9pL/IORzyGmnsf+g9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q8NHQ9 intact:EBI-6377335 intact:EBI-5459844|uniprotkb:Q8IYH0|uniprotkb:Q658L6|uniprotkb:Q9HCH7|ensembl:ENSP00000238146 psi-mi:p27958-pro_0000037566(display_long) psi-mi:ddx55_human(display_long)|uniprotkb:DDX55(gene name)|psi-mi:DDX55(display_short)|uniprotkb:KIAA1595(gene name synonym)|uniprotkb:DEAD box protein 55(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_065987.1|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313|interpro:IPR027417|ensembl:ENSG00000111364(gene)|ensembl:ENST00000238146(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity) - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:VVL8J5YYSl65518bjXSAwkRadLQ9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P62888 intact:EBI-6377335 intact:EBI-353116|uniprotkb:P04645|uniprotkb:Q502Z6|ensembl:ENSP00000287038|ensembl:ENSP00000428085|uniprotkb:B2R591 psi-mi:p27958-pro_0000037566(display_long) psi-mi:rl30_human(display_long)|uniprotkb:RPL30(gene name)|psi-mi:RPL30(display_short)|uniprotkb:Large ribosomal subunit protein eL30(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000156482(gene)|ensembl:ENST00000287038(transcript)|ensembl:ENST00000521291(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000231(Ribosomal protein L30e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR022991|interpro:IPR029064|interpro:IPR039109|mint:P62888|rcsb pdb:3VI6|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000980.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:xR9LwYg6N7m9njT1pYumOPKZVu49606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P47914 intact:EBI-6377335 intact:EBI-714039|uniprotkb:Q6IPY3|ensembl:ENSP00000418346|ensembl:ENSP00000418868|ensembl:ENSP00000420673|ensembl:ENSP00000294189|ensembl:ENSP00000417048|ensembl:ENSP00000418153|uniprotkb:B2R4M8|uniprotkb:A8K0H3 psi-mi:p27958-pro_0000037566(display_long) psi-mi:rl29_human(display_long)|uniprotkb:Cell surface heparin-binding protein HIP(gene name synonym)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)|uniprotkb:Large ribosomal subunit protein eL29(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENST00000294189(transcript)|ensembl:ENST00000466397(transcript)|ensembl:ENST00000475248(transcript)|ensembl:ENST00000479017(transcript)|ensembl:ENST00000492277(transcript)|ensembl:ENST00000495383(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007566"(embryo implantation)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|ensembl:ENSG00000162244(gene)|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000983.1|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:XZUSMDDzycAi6QEXYbljXaeVg0U9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q13243 intact:EBI-6377335 intact:EBI-720503|uniprotkb:O14797|uniprotkb:Q16662|uniprotkb:Q49AD6|uniprotkb:Q6FGE0|ensembl:ENSP00000377892|ensembl:ENSP00000451088|ensembl:ENSP00000452123 psi-mi:p27958-pro_0000037566(display_long) psi-mi:srsf5_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short)|uniprotkb:HRS(gene name synonym)|uniprotkb:SRP40(gene name synonym)|uniprotkb:SFRS5(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) go:"GO:0003729"(mRNA binding)|refseq:NP_001034554.1|refseq:NP_008856.2|refseq:NP_001307143.1|dip:DIP-46894N|ensembl:ENSG00000100650(gene)|ensembl:ENST00000394366(transcript)|ensembl:ENST00000553521(transcript)|ensembl:ENST00000557154(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q13243|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73856 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:q+kwVNXjDcA8o9hJ+BDF0S5ZSlY9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q13242 intact:EBI-6377335 intact:EBI-2949710|ensembl:ENSP00000229390|uniprotkb:Q52LD1 psi-mi:p27958-pro_0000037566(display_long) psi-mi:srsf9_human(display_long)|uniprotkb:SRSF9(gene name)|psi-mi:SRSF9(display_short)|uniprotkb:SFRS9(gene name synonym)|uniprotkb:SRP30C(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRp30C(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 9(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) go:"GO:0006397"(mRNA processing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0006376"(mRNA splice site selection)|interpro:IPR034503|interpro:IPR034995|interpro:IPR035979|mint:Q13242|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|ensembl:ENSG00000111786(gene)|ensembl:ENST00000229390(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_003760.1|dip:DIP-40741N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:9x6TWFk1zN1YodjXBiwi/MtNJe49606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P35268 intact:EBI-6377335 intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088 psi-mi:p27958-pro_0000037566(display_long) psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P09132 intact:EBI-6377335 intact:EBI-2680090|uniprotkb:B2R4E9|uniprotkb:Q96FG6|uniprotkb:Q05D77|uniprotkb:D6RCQ5|ensembl:ENSP00000424870 psi-mi:p27958-pro_0000037566(display_long) psi-mi:srp19_human(display_long)|uniprotkb:SRP19(gene name)|psi-mi:SRP19(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001191123.1|refseq:NP_003126.1|refseq:NP_001191122.1|refseq:NP_001191125.1|ensembl:ENSG00000153037(gene)|ensembl:ENST00000505459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR002778(Signal recognition particle, SRP19 subunit)|interpro:IPR036521|mint:P09132|rcsb pdb:1JID|rcsb pdb:1MFQ|rcsb pdb:1RY1|rcsb pdb:2J37|rcsb pdb:3KTV|rcsb pdb:4P3E|rcsb pdb:5M73|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-41412N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:yIFmf1q6m2wQt3eaiCc1dlIQXn89606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:O14602 intact:EBI-6377335 intact:EBI-286439|uniprotkb:Q9BS77|ensembl:ENSP00000354722 psi-mi:p27958-pro_0000037566(display_long) psi-mi:if1ay_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 4C(gene name synonym)|uniprotkb:EIF1AY(gene name)|psi-mi:EIF1AY(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_004672.2|refseq:NP_001265541.1|ensembl:ENSG00000198692(gene)|ensembl:ENST00000361365(transcript)|go:"GO:0003743"(translation initiation factor activity)|interpro:IPR001253("Eukaryotic initiation factor 1A (eIF-1A)")|interpro:IPR006196(S1, IF1 type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018104 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:8nbys9cgdyGlFgYev/Ws9Q0cu6s9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P62750 intact:EBI-6377335 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:p27958-pro_0000037566(display_long) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q15020 intact:EBI-6377335 intact:EBI-308619|uniprotkb:Q2M2H0|uniprotkb:Q58F06|uniprotkb:Q8IUS1|uniprotkb:Q96J95|uniprotkb:A8K2E4|uniprotkb:B7ZKM0|ensembl:ENSP00000449386|intact:EBI-11138149 psi-mi:p27958-pro_0000037566(display_long) psi-mi:sart3_human(display_long)|uniprotkb:KIAA0156(gene name synonym)|uniprotkb:SART3(gene name)|psi-mi:SART3(display_short)|uniprotkb:TIP110(gene name synonym)|uniprotkb:Tat-interacting protein of 110 kDa(gene name synonym)|uniprotkb:p110 nuclear RNA-binding protein(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000075856(gene)|ensembl:ENST00000546815(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030624"(U6atac snRNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0061574"(ASAP complex)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903586"(positive regulation of histone deubiquitination)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008669(Lsm interaction)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034217|interpro:IPR034218|interpro:IPR035979|mint:Q15020|rcsb pdb:2DO4|rcsb pdb:5CTQ|rcsb pdb:5CTR|rcsb pdb:5CTT|rcsb pdb:5JJW|rcsb pdb:5JJX|rcsb pdb:5JPZ|refseq:NP_055521.1 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:/71mWOMJti/LCvNo2WjCAmIYUCk9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q6ZT98 intact:EBI-6377335 intact:EBI-8787436|uniprotkb:Q5TAX8|uniprotkb:Q5TAX9|uniprotkb:Q6P990|uniprotkb:Q86YS1|uniprotkb:Q9H5U4|ensembl:ENSP00000260505 psi-mi:p27958-pro_0000037566(display_long) psi-mi:ttll7_human(display_long)|uniprotkb:TTLL7(gene name)|psi-mi:TTLL7(display_short)|uniprotkb:Testis development protein NYD-SP30(gene name synonym)|uniprotkb:Tubulin--tyrosine ligase-like protein 7(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:XP_016857836.1|refseq:NP_078962.4|ensembl:ENSG00000137941(gene)|ensembl:ENST00000260505(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007399"(nervous system development)|go:"GO:0015631"(tubulin binding)|go:"GO:0018095"(protein polyglutamylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070740"(tubulin-glutamic acid ligase activity)|interpro:IPR004344(Tubulin-tyrosine ligase)|rcsb pdb:4YLS|reactome:R-HSA-8955332|rcsb pdb:4YLR - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:WfjEZP2NWdBb6fT5cYHoZrtNbqI9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q9Y237 intact:EBI-6377335 intact:EBI-714599|ensembl:ENSP00000362773|uniprotkb:Q5HYW6|uniprotkb:A8E0G6|uniprotkb:Q6IRW4|uniprotkb:Q0D2H3|uniprotkb:Q3MHV0|uniprotkb:Q52M21|uniprotkb:B3KXM0|uniprotkb:F5H1P5 psi-mi:p27958-pro_0000037566(display_long) psi-mi:pin4_human(display_long)|uniprotkb:Parvulin-17(gene name synonym)|uniprotkb:Rotamase Pin4(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin4(gene name synonym)|uniprotkb:Parvulin-14(gene name synonym)|uniprotkb:Peptidyl-prolyl cis/trans isomerase EPVH(gene name synonym)|uniprotkb:PIN4(gene name)|psi-mi:PIN4(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) ensembl:ENSG00000102309(gene)|ensembl:ENST00000373669(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003681"(bent DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001164218.1|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006364"(rRNA processing)|go:"GO:0030684"(preribosome)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|interpro:IPR043323|rcsb pdb:1EQ3|rcsb pdb:1FJD|rcsb pdb:3UI4|rcsb pdb:3UI5|rcsb pdb:3UI6|refseq:NP_006214.2|go:"GO:0005694"(chromosome)|dip:DIP-50838N - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:fqn1yVv3BoIxVdsY4VSzGFWWir09606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q53F19 intact:EBI-6377335 intact:EBI-6657994|uniprotkb:Q9NXZ4|uniprotkb:B3KWG7|uniprotkb:Q96FK1|uniprotkb:Q7L406|ensembl:ENSP00000373657 psi-mi:p27958-pro_0000037566(display_long) psi-mi:ncbp3_human(display_long)|uniprotkb:C17orf85(gene name synonym)|uniprotkb:Protein ELG(gene name synonym)|uniprotkb:NCBP3(gene name)|psi-mi:NCBP3(display_short) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:XP_016880318.1|refseq:NP_001107590.1|ensembl:ENSG00000074356(gene)|ensembl:ENST00000389005(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0016607"(nuclear speck)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019416 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:R4Oebjb9RKooXqVvOAkkNMmPYq49606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27958-PRO_0000037566 uniprotkb:P22736 intact:EBI-6377335 intact:EBI-721550|uniprotkb:B4DML7|ensembl:ENSP00000243050|ensembl:ENSP00000378301|ensembl:ENSP00000378302|uniprotkb:Q15627|uniprotkb:Q53Y00|uniprotkb:Q6IBU8 psi-mi:p27958-pro_0000037566(display_long) psi-mi:nr4a1_human(display_long)|uniprotkb:Orphan nuclear receptor HMR(gene name synonym)|uniprotkb:Early response protein NAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR3(gene name synonym)|uniprotkb:ST-59(gene name synonym)|uniprotkb:GFRP1(gene name synonym)|uniprotkb:HMR(gene name synonym)|uniprotkb:NAK1(gene name synonym)|uniprotkb:NR4A1(gene name)|psi-mi:NR4A1(display_short)|uniprotkb:Nuclear hormone receptor NUR/77(gene name synonym)|uniprotkb:Testicular receptor 3(gene name synonym) psi-mi:"MI:0089"(protein array) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785468|imex:IM-26077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_001189162.1|refseq:NP_002126.2|refseq:NP_775180.1|ensembl:ENSG00000123358(gene)|ensembl:ENST00000243050(transcript)|ensembl:ENST00000394824(transcript)|ensembl:ENST00000394825(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|dip:DIP-40392N|refseq:XP_005268881.1|refseq:XP_006719426.1|refseq:XP_006719427.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014860"(neurotransmitter secretion involved in regulation of skeletal muscle contraction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|go:"GO:0098793"(presynapse)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR003071(Orphan nuclear receptor, HMR type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P22736|rcsb pdb:2QW4|rcsb pdb:3V3E|rcsb pdb:3V3Q|rcsb pdb:4JGV|rcsb pdb:4KZI|rcsb pdb:4KZJ|rcsb pdb:4KZM|rcsb pdb:4RE8|rcsb pdb:4REE|rcsb pdb:4REF|rcsb pdb:4RZE|rcsb pdb:4RZF|rcsb pdb:4RZG|rcsb pdb:4WHF|rcsb pdb:4WHG|rcsb pdb:6KZ5|rcsb pdb:6LC1|reactome:R-HSA-198693|reactome:R-HSA-383280|reactome:R-HSA-5674400 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 1 and table 2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/10/02 2018/04/06 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:yocf+C94vprIeNXXB89p3tqzW/c9606 intact-crc:4EB1883EC605AF78|rigid:Aqxzb7UA1UsQfdO+7oXzeyCqQkw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q16644 uniprotkb:P27958-PRO_0000037566 intact:EBI-1384657|uniprotkb:B5BU67|ensembl:ENSP00000350639|ensembl:ENSP00000396467|ensembl:ENSP00000478922 intact:EBI-6377335 psi-mi:mapk3_human(display_long)|uniprotkb:Chromosome 3p kinase(gene name synonym)|uniprotkb:MAPKAPK3(gene name)|psi-mi:MAPKAPK3(display_short) psi-mi:p27958-pro_0000037566(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8850746|imex:IM-26077-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004626.1|refseq:NP_001230854.1|refseq:NP_001230855.1|reactome:R-HSA-2559580|reactome:R-HSA-4420097|reactome:R-HSA-450302|ensembl:ENSG00000114738(gene)|ensembl:ENST00000357955(transcript)|ensembl:ENST00000446044(transcript)|ensembl:ENST00000621469(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044351"(macropinocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027442|mint:Q16644|rcsb pdb:3FHR|rcsb pdb:3FXW|rcsb pdb:3R1N|rcsb pdb:3SHE|reactome:R-HSA-171007 intact:EBI-706378(chain-parent) - - chain-seq-start:2|chain-seq-end:191 figure legend:Fig. 3B, 3E and 4B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/10/02 2017/09/02 rogid:pb+7uZ1B8LMFi5DrfRi70X9Xbks9606 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 intact-crc:14D0AB92D41B4CA0|rigid:D2S8ti/tkYnNUIyvUJ286JsW4Ic false flag tag:?-? necessary binding region:41-75|myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q16644 uniprotkb:P27958-PRO_0000037566 intact:EBI-1384657|uniprotkb:B5BU67|ensembl:ENSP00000350639|ensembl:ENSP00000396467|ensembl:ENSP00000478922 intact:EBI-6377335 psi-mi:mapk3_human(display_long)|uniprotkb:Chromosome 3p kinase(gene name synonym)|uniprotkb:MAPKAPK3(gene name)|psi-mi:MAPKAPK3(display_short) psi-mi:p27958-pro_0000037566(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785492|imex:IM-26077-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004626.1|refseq:NP_001230854.1|refseq:NP_001230855.1|reactome:R-HSA-2559580|reactome:R-HSA-4420097|reactome:R-HSA-450302|ensembl:ENSG00000114738(gene)|ensembl:ENST00000357955(transcript)|ensembl:ENST00000446044(transcript)|ensembl:ENST00000621469(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044351"(macropinocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027442|mint:Q16644|rcsb pdb:3FHR|rcsb pdb:3FXW|rcsb pdb:3R1N|rcsb pdb:3SHE|reactome:R-HSA-171007 intact:EBI-706378(chain-parent) - - chain-seq-start:2|chain-seq-end:191 figure legend:Fig. 3B, 3E and 4D|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/10/02 2017/09/02 rogid:pb+7uZ1B8LMFi5DrfRi70X9Xbks9606 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 intact-crc:14D50B92D41B4CA0|rigid:D2S8ti/tkYnNUIyvUJ286JsW4Ic false flag tag:?-?|sufficient binding region:1-182 myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q16644 intact:EBI-6377335 intact:EBI-1384657|uniprotkb:B5BU67|ensembl:ENSP00000350639|ensembl:ENSP00000396467|ensembl:ENSP00000478922 psi-mi:p27958-pro_0000037566(display_long) psi-mi:mapk3_human(display_long)|uniprotkb:Chromosome 3p kinase(gene name synonym)|uniprotkb:MAPKAPK3(gene name)|psi-mi:MAPKAPK3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8785510|imex:IM-26077-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_004626.1|refseq:NP_001230854.1|refseq:NP_001230855.1|reactome:R-HSA-2559580|reactome:R-HSA-4420097|reactome:R-HSA-450302|ensembl:ENSG00000114738(gene)|ensembl:ENST00000357955(transcript)|ensembl:ENST00000446044(transcript)|ensembl:ENST00000621469(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044351"(macropinocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027442|mint:Q16644|rcsb pdb:3FHR|rcsb pdb:3FXW|rcsb pdb:3R1N|rcsb pdb:3SHE|reactome:R-HSA-171007 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 3C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh-7.5)|taxid:9606(Human Huh-7.5 cells) - 2013/10/02 2017/09/02 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:pb+7uZ1B8LMFi5DrfRi70X9Xbks9606 intact-crc:D14EBC77A7D7AF37|rigid:D2S8ti/tkYnNUIyvUJ286JsW4Ic false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P27958-PRO_0000037566 uniprotkb:Q16644 intact:EBI-6377335 intact:EBI-1384657|uniprotkb:B5BU67|ensembl:ENSP00000350639|ensembl:ENSP00000396467|ensembl:ENSP00000478922 psi-mi:p27958-pro_0000037566(display_long) psi-mi:mapk3_human(display_long)|uniprotkb:Chromosome 3p kinase(gene name synonym)|uniprotkb:MAPKAPK3(gene name)|psi-mi:MAPKAPK3(display_short) psi-mi:"MI:0096"(pull down) Ngo et al. (2013) pubmed:23487458|imex:IM-26077 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-8850724|imex:IM-26077-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-706378(chain-parent) refseq:NP_004626.1|refseq:NP_001230854.1|refseq:NP_001230855.1|reactome:R-HSA-2559580|reactome:R-HSA-4420097|reactome:R-HSA-450302|ensembl:ENSG00000114738(gene)|ensembl:ENST00000357955(transcript)|ensembl:ENST00000446044(transcript)|ensembl:ENST00000621469(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044351"(macropinocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027442|mint:Q16644|rcsb pdb:3FHR|rcsb pdb:3FXW|rcsb pdb:3R1N|rcsb pdb:3SHE|reactome:R-HSA-171007 - chain-seq-start:2|chain-seq-end:191 - figure legend:Fig. 3A|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/10/02 2014/10/16 rogid:Uu1VBCE+GpBd6zd2H1GuhUh/0tA63746 rogid:pb+7uZ1B8LMFi5DrfRi70X9Xbks9606 intact-crc:7A2D11B9EFF5F507|rigid:D2S8ti/tkYnNUIyvUJ286JsW4Ic false his tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)