#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P33767 uniprotkb:P41811 intact:EBI-12658|uniprotkb:D3DLP5|ensemblfungi:YEL002C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:ostb_yeast(display_long)|uniprotkb:WBP1(gene name)|psi-mi:WBP1(display_short)|uniprotkb:Oligosaccharyl transferase subunit beta(gene name synonym)|uniprotkb:YEL002C(locus name) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8503532|mint:MINT-8430892|imex:IM-27961-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YEL002C(gene)|ensemblfungi:YEL002C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|rcsb pdb:4J86|rcsb pdb:6C26|rcsb pdb:6EZN|reactome:R-SCE-6798695|refseq:NP_010914.3|sgd:S000000728|mint:P33767|dip:DIP-676N|mint:MINT-8430894(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8430896(identity) - crc64:495DA76BE8A9B29A crc64:6A5E50BBEB02CB58 comment:homomint|comment:mint|figure legend:t1 sf1a|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2020/05/07 rogid:hSnp48laqjCzA32hSJblrQ/5q5E559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:4863F62CFD422C66|rigid:3roQxcp0e5qr8rYLqmQ/sbF6mFw false binding-associated region:425-430(MINT-8430910) binding-associated region:1-301(MINT-8430897)|his tag:?-?(MINT-8430899) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3T133 uniprotkb:P41811 intact:EBI-7916988|intact:UNK-5914408|uniprotkb:Q5E957|ensembl:ENSBTAP00000001830 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:tmed9_bovin(display_long)|uniprotkb:p24 family protein alpha-2(gene name synonym)|uniprotkb:TMED9(gene name)|psi-mi:TMED9(display_short) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8503511|mint:MINT-8430877|imex:IM-27961-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001029984.1|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048205"(COPI coating of Golgi vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q3T133|rcsb pdb:4J73|ensembl:ENSBTAG00000001394(gene)|ensembl:ENSBTAT00000001830(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|mint:MINT-8430880(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8430879(identity) - comment:mint|comment:homomint crc64:6A5E50BBEB02CB58 comment:homomint|comment:mint|figure legend:t1 f2c f3a f3c f7a|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2020/05/07 rogid:pmhoiawlhPG24Y+zz/BbHp29dpQ9913 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:81CD963CE08B9AC2|rigid:KRhK1B8myEys3lkDHC59HsZQIHk false binding-associated region:229-235(MINT-8430917) binding-associated region:1-301(MINT-8430887)|his tag:?-?(MINT-8430884) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39656 uniprotkb:P41811 intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457|uniprotkb:B4DJE3|uniprotkb:B4DLI2 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8503553|mint:MINT-8430920|imex:IM-27961-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005207.2|ensembl:ENSG00000244038(gene)|ensembl:ENST00000415136(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034097"(response to cytokine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042110"(T cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548|mint:MINT-8430922(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8430926(identity) - - crc64:6A5E50BBEB02CB58 comment:homomint|comment:mint|figure legend:t1 F3B F3D|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2020/05/07 rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:FF7C9F7B8C6AB694|rigid:xl+ieNBXKjCfYvM88JbxrCH+tNg false binding-associated region:451-456(MINT-8430923) his tag:?-?(MINT-8430929)|binding-associated region:1-301(MINT-8430927) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) intact:EBI-8503574 uniprotkb:P41811 intact:MINT-8430971 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:a0a3f3ey22_yeasa(display_short)|psi-mi:EBI-8503574(display_long)|uniprotkb:AWRI796_1468(orf name) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:764097(yeasa)|taxid:764097("Saccharomyces cerevisiae (strain AWRI796)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8503586|mint:MINT-8430952|imex:IM-27961-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A0A3F3EY22(uniprot-removed-ac)|mint:MINT-8430954(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8430958(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:mint crc64:6A5E50BBEB02CB58 comment:mint|figure legend:t1 F1g f2d f4a f5a f7a|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2020/05/07 rogid:lLKyvNDfngKfVQ7idM4VteCNrt4764097 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:19487E11D65F8D08|rigid:lAVSk4CF0RqbrW5oDDD93EFZiXg false binding-associated region:440-445(MINT-8430955) binding-associated region:1-301(MINT-8430961)|his tag:?-?(MINT-8430959) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) intact:EBI-8503611 uniprotkb:P41811 intact:MINT-8431037 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:scyl1(display_short)|psi-mi:EBI-8503611(display_long) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8503606|mint:MINT-8430981|imex:IM-27961-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) mint:MINT-8431039(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8430987(identity) - comment:mint|no-uniprot-update: crc64:6A5E50BBEB02CB58 comment:mint|figure legend:t1 f5a|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2020/05/07 rogid:i2sWLOTBA5/GAcia1akBtsLdgfI-2 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:77E5C60B50FD2780|rigid:glpzaVZeSwSDvP3UjuySSAgSPS0 false - his tag:?-?(MINT-8430990)|binding-associated region:1-301(MINT-8430988) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41811 uniprotkb:O15503 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-6252425|ensembl:ENSP00000344741|uniprotkb:A8K6L0|uniprotkb:Q53XW8|uniprotkb:Q9BUV5|uniprotkb:A4D2N1 psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:insi1_human(display_long)|uniprotkb:INSIG1(gene name)|psi-mi:INSIG1(display_short) psi-mi:"MI:0114"(x-ray crystallography) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8503673|mint:MINT-8431081|imex:IM-27961-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431087(identity) ensembl:ENSG00000186480(gene)|ensembl:ENST00000340368(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0010894"(negative regulation of steroid biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032937"(SREBP-SCAP-Insig complex)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0036316"(SREBP-SCAP complex retention in endoplasmic reticulum)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:1901303"(negative regulation of cargo loading into COPII-coated vesicle)|interpro:IPR009904(Insulin-induced)|interpro:IPR025929|mint:O15503|rcsb pdb:4J81|reactome:R-HSA-1655829|go:"GO:0070862"(negative regulation of protein exit from endoplasmic reticulum)|refseq:NP_001333519.1|refseq:NP_001333520.1|refseq:NP_001333521.1|refseq:NP_001333522.1|refseq:NP_001333523.1|refseq:NP_005533.2|refseq:NP_938150.2|refseq:NP_938151.1|dip:DIP-61157N|refseq:XP_016867666.1|mint:MINT-8431083(identity) - crc64:6A5E50BBEB02CB58 - comment:homomint|comment:mint|figure legend:t1 F4a|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2020/05/07 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:CePNtn7b6ienEbjTcmzRblg0FnE9606 intact-crc:36F60BA31FCCCAF9|rigid:NfcZFs7KSsatdcNM3Q8VUuLUTzo false his tag:?-?(MINT-8431088)|binding-associated region:1-301(MINT-8431090) binding-associated region:272-277(MINT-8431084) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) intact:EBI-8503574 uniprotkb:Q96WV5 intact:MINT-8430971 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" psi-mi:a0a3f3ey22_yeasa(display_short)|psi-mi:EBI-8503574(display_long)|uniprotkb:AWRI796_1468(orf name) psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:764097(yeasa)|taxid:764097("Saccharomyces cerevisiae (strain AWRI796)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8503694|mint:MINT-8431107|imex:IM-27961-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A0A3F3EY22(uniprot-removed-ac)|mint:MINT-8431109(identity) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431113(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:mint comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins comment:mint|figure legend:t1 F2b|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2020/05/07 rogid:lLKyvNDfngKfVQ7idM4VteCNrt4764097 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 intact-crc:4D1AC54AB2B45B0D|rigid:c6LRKVgfoGt8uTHy7FWYDE1Q/WE false binding-associated region:440-445(MINT-8431110) his tag:?-?(MINT-8431116)|binding-associated region:1-327(MINT-8431114) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91AV1 uniprotkb:P41811 intact:EBI-8503634|intact:MINT-8431061 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:spike_pedv7(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:229032(pedv)|taxid:229032("Porcine epidemic diarrhea virus (strain CV777)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8503628|mint:MINT-8431043|imex:IM-27961-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR042552|interpro:IPR043607|interpro:IPR043614|interpro:IPR002552(Coronavirus S2 glycoprotein)|refseq:NP_598310.1|interpro:IPR002551(Coronavirus S1 glycoprotein)|rcsb pdb:4J79|rcsb pdb:6U7K|interpro:IPR043473|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR044873|interpro:IPR044874|mint:MINT-8431045(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431049(identity) - comment:mint|comment:homomint crc64:6A5E50BBEB02CB58 comment:homomint|comment:mint|figure legend:t1 F4b|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2020/05/07 rogid:GsfcvtFlfI19W4JisYC7vFmdhek229032 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:3571E80532A1507A|rigid:ok9WEBkQkT2Jc9Q0vXiUtsudvEk false binding-associated region:1377-1383(MINT-8431046) binding-associated region:1-301(MINT-8431050)|his tag:?-?(MINT-8431052) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96WV5 uniprotkb:P68978 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" intact:EBI-4407041|uniprotkb:P03251 psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:e3gl_ade02(display_long)|uniprotkb:E3-19K(gene name synonym)|uniprotkb:E3gp 19 kDa(gene name synonym)|uniprotkb:GP19K(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:10515(ade02)|taxid:10515("Human adenovirus C serotype 2 (HAdV-2)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8503791|mint:MINT-8431238|imex:IM-27961-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431244(identity) refseq:AP_000184.1|refseq:NP_040531.1|interpro:IPR006965(Adenovirus GP19K)|interpro:IPR038710|go:"GO:0005537"(mannose binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039591"|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|mint:MINT-8431240(identity) - comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins - comment:mint|figure legend:t1 F1f f2a|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2020/05/07 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 rogid:XJsAfLwKM8ClP2oC6/tkRHrf1Zk10515 intact-crc:D750F7B63312679C|rigid:pGyYOsNHFYKybsdvfsOHuXQ22aE false binding-associated region:1-327(MINT-8431247)|his tag:?-?(MINT-8431245) binding-associated region:148-159(MINT-8431241) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q9Y5U4 uniprotkb:P41811 intact:EBI-8503746|intact:MINT-8431157|uniprotkb:Q8TBI8|uniprotkb:A8K5W8|ensembl:ENSP00000245787 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:insi2_human(display_long)|uniprotkb:INSIG2(gene name)|psi-mi:INSIG2(display_short) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8503740|mint:MINT-8431214|imex:IM-27961-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308259.1|refseq:NP_001308260.1|refseq:NP_001308261.1|refseq:NP_001308262.1|refseq:NP_001308258.1|refseq:NP_057217.2|dip:DIP-60913N|ensembl:ENSG00000125629(gene)|ensembl:ENST00000245787(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0010894"(negative regulation of steroid biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032937"(SREBP-SCAP-Insig complex)|go:"GO:0036316"(SREBP-SCAP complex retention in endoplasmic reticulum)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:0070542"(response to fatty acid)|interpro:IPR025929|rcsb pdb:4J82|rcsb pdb:6M49|rcsb pdb:7ETW|reactome:R-HSA-1655829|mint:MINT-8431216(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431220(identity) - comment:mint|comment:homomint crc64:6A5E50BBEB02CB58 figure legend:t1|comment:homomint|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2020/05/07 rogid:u6hydxrFnhRfWQ4LuogzQ+P/S1I9606 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:DAA870439497C605|rigid:aEE1XrfylCo4vnisFQJbJmVEIdY false binding-associated region:218-225(MINT-8431217) binding-associated region:1-301(MINT-8431221)|his tag:?-?(MINT-8431223) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 uniprotkb:P41811 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8503818|mint:MINT-8431140|imex:IM-27961-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431173(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431146(identity) - crc64:D3589073106F5570 crc64:6A5E50BBEB02CB58 comment:homomint|figure legend:f2f|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:27.7x10^-6(molar) 2013/05/20 2014/10/16 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:B91B069BF512E8D4|rigid:ss3Gkw9DuQGCAVB06lAxKYaaNus false his tag:?-?(MINT-8431181)|binding-associated region:624-818(MINT-8431184) binding-associated region:1-814(MINT-8431147)|his tag:?-?(MINT-8431149) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 uniprotkb:Q3T133 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-7916988|intact:UNK-5914408|uniprotkb:Q5E957|ensembl:ENSBTAP00000001830 psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:tmed9_bovin(display_long)|uniprotkb:p24 family protein alpha-2(gene name synonym)|uniprotkb:TMED9(gene name)|psi-mi:TMED9(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8503818|mint:MINT-8431140|imex:IM-27961-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431173(identity) refseq:NP_001029984.1|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048205"(COPI coating of Golgi vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q3T133|rcsb pdb:4J73|ensembl:ENSBTAG00000001394(gene)|ensembl:ENSBTAT00000001830(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|mint:MINT-8431142(identity) - crc64:D3589073106F5570 comment:mint|comment:homomint comment:homomint|figure legend:f2f|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:27.7x10^-6(molar) 2013/05/20 2014/10/16 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:pmhoiawlhPG24Y+zz/BbHp29dpQ9913 intact-crc:B91B069BF512E8D4|rigid:ss3Gkw9DuQGCAVB06lAxKYaaNus false his tag:?-?(MINT-8431181)|binding-associated region:624-818(MINT-8431184) binding-associated region:229-235(MINT-8431143) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P53622 uniprotkb:P41811 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8503878|mint:MINT-8431254|imex:IM-27961-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431267(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431261(identity) - crc64:D3589073106F5570 crc64:6A5E50BBEB02CB58 comment:homomint|figure legend:f2f|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:170.9x10^-6(molar) 2013/05/20 2014/10/16 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:AE3B6A4F2F1CF86E|rigid:5O+lhcq5Ez5h64C5eF8IHAERp8s false binding-associated region:624-818(MINT-8431270)|his tag:?-?(MINT-8431268) his tag:?-?(MINT-8431264)|binding-associated region:1-814(MINT-8431262) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 uniprotkb:P33767 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-12658|uniprotkb:D3DLP5|ensemblfungi:YEL002C psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:ostb_yeast(display_long)|uniprotkb:WBP1(gene name)|psi-mi:WBP1(display_short)|uniprotkb:Oligosaccharyl transferase subunit beta(gene name synonym)|uniprotkb:YEL002C(locus name) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8503878|mint:MINT-8431254|imex:IM-27961-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431267(identity) ensemblfungi:YEL002C(gene)|ensemblfungi:YEL002C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|rcsb pdb:4J86|rcsb pdb:6C26|rcsb pdb:6EZN|reactome:R-SCE-6798695|refseq:NP_010914.3|sgd:S000000728|mint:P33767|dip:DIP-676N|mint:MINT-8431257(identity) - crc64:D3589073106F5570 crc64:495DA76BE8A9B29A comment:homomint|figure legend:f2f|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:170.9x10^-6(molar) 2013/05/20 2014/10/16 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:hSnp48laqjCzA32hSJblrQ/5q5E559292 intact-crc:AE3B6A4F2F1CF86E|rigid:5O+lhcq5Ez5h64C5eF8IHAERp8s false binding-associated region:624-818(MINT-8431270)|his tag:?-?(MINT-8431268) binding-associated region:425-430(MINT-8431258) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P53622 uniprotkb:P41811 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8503848|mint:MINT-8431194|imex:IM-27961-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431197(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431203(identity) - crc64:D3589073106F5570 crc64:6A5E50BBEB02CB58 comment:homomint|figure legend:f2f|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:49.0x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:576657EB82D89F80|rigid:edSDLYXmjzsRXy0qOaIxOlXdvVQ false binding-associated region:624-818(MINT-8431198)|his tag:?-?(MINT-8431200) his tag:?-?(MINT-8431204)|binding-associated region:1-814(MINT-8431206) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 uniprotkb:P68978 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4407041|uniprotkb:P03251 psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:e3gl_ade02(display_long)|uniprotkb:E3-19K(gene name synonym)|uniprotkb:E3gp 19 kDa(gene name synonym)|uniprotkb:GP19K(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:10515(ade02)|taxid:10515("Human adenovirus C serotype 2 (HAdV-2)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8503848|mint:MINT-8431194|imex:IM-27961-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431197(identity) refseq:AP_000184.1|refseq:NP_040531.1|interpro:IPR006965(Adenovirus GP19K)|interpro:IPR038710|go:"GO:0005537"(mannose binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039591"|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|mint:MINT-8431209(identity) - crc64:D3589073106F5570 - comment:homomint|figure legend:f2f|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:49.0x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:XJsAfLwKM8ClP2oC6/tkRHrf1Zk10515 intact-crc:576657EB82D89F80|rigid:edSDLYXmjzsRXy0qOaIxOlXdvVQ false binding-associated region:624-818(MINT-8431198)|his tag:?-?(MINT-8431200) binding-associated region:148-159(MINT-8431210) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P53622 uniprotkb:P41811 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8503908|mint:MINT-8431280|imex:IM-27961-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431287(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431293(identity) - crc64:D3589073106F5570 crc64:6A5E50BBEB02CB58 comment:homomint|comment:mint|figure legend:f2h|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.4x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:F2A6018C52A3D005|rigid:ZEr+J62NZHYSJIh/S687klQeIw0 false binding-associated region:624-818(MINT-8431288)|his tag:?-?(MINT-8431290) binding-associated region:1-814(MINT-8431296)|his tag:?-?(MINT-8431294) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 uniprotkb:P39656 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457|uniprotkb:B4DJE3|uniprotkb:B4DLI2 psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8503908|mint:MINT-8431280|imex:IM-27961-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431287(identity) refseq:NP_005207.2|ensembl:ENSG00000244038(gene)|ensembl:ENST00000415136(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034097"(response to cytokine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042110"(T cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548|mint:MINT-8431283(identity) - crc64:D3589073106F5570 - comment:homomint|comment:mint|figure legend:f2h|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.4x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606 intact-crc:F2A6018C52A3D005|rigid:ZEr+J62NZHYSJIh/S687klQeIw0 false binding-associated region:624-818(MINT-8431288)|his tag:?-?(MINT-8431290) binding-associated region:451-456(MINT-8431284) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) intact:EBI-8503574 uniprotkb:P53622 intact:MINT-8430971 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C psi-mi:a0a3f3ey22_yeasa(display_short)|psi-mi:EBI-8503574(display_long)|uniprotkb:AWRI796_1468(orf name) psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:764097(yeasa)|taxid:764097("Saccharomyces cerevisiae (strain AWRI796)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8503938|mint:MINT-8431302|imex:IM-27961-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A0A3F3EY22(uniprot-removed-ac)|mint:MINT-8431305(identity) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431315(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:mint crc64:D3589073106F5570 comment:mint|figure legend:f2h|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:22.5x10^-6(molar) 2013/05/20 2020/05/07 rogid:lLKyvNDfngKfVQ7idM4VteCNrt4764097 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 intact-crc:1B59B0F6AFA942B3|rigid:otG/uU1gvhioL+UhINtuUV8kRzk false binding-associated region:440-445(MINT-8431306) his tag:?-?(MINT-8431316)|binding-associated region:624-818(MINT-8431318) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) intact:EBI-8503574 uniprotkb:P41811 intact:MINT-8430971 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:a0a3f3ey22_yeasa(display_short)|psi-mi:EBI-8503574(display_long)|uniprotkb:AWRI796_1468(orf name) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:764097(yeasa)|taxid:764097("Saccharomyces cerevisiae (strain AWRI796)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8503938|mint:MINT-8431302|imex:IM-27961-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A0A3F3EY22(uniprot-removed-ac)|mint:MINT-8431305(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431309(identity) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:mint crc64:6A5E50BBEB02CB58 comment:mint|figure legend:f2h|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:22.5x10^-6(molar) 2013/05/20 2020/05/07 rogid:lLKyvNDfngKfVQ7idM4VteCNrt4764097 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:1B59B0F6AFA942B3|rigid:otG/uU1gvhioL+UhINtuUV8kRzk false binding-associated region:440-445(MINT-8431306) his tag:?-?(MINT-8431312)|binding-associated region:1-814(MINT-8431310) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3T133 uniprotkb:Q96WV5 intact:EBI-7916988|intact:UNK-5914408|uniprotkb:Q5E957|ensembl:ENSBTAP00000001830 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" psi-mi:tmed9_bovin(display_long)|uniprotkb:p24 family protein alpha-2(gene name synonym)|uniprotkb:TMED9(gene name)|psi-mi:TMED9(display_short) psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8503967|mint:MINT-8431324|imex:IM-27961-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001029984.1|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048205"(COPI coating of Golgi vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q3T133|rcsb pdb:4J73|ensembl:ENSBTAG00000001394(gene)|ensembl:ENSBTAT00000001830(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|mint:MINT-8431339(identity) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431327(identity) - comment:mint|comment:homomint comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins figure legend:f2e|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:11.3x10^-6(molar) 2013/05/20 2020/05/07 rogid:pmhoiawlhPG24Y+zz/BbHp29dpQ9913 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 intact-crc:8691C820D8F0C761|rigid:GhdgdUZcNiXcXpL2FvAlThJWA88 false binding-associated region:229-235(MINT-8431340) his tag:?-?(MINT-8431330)|binding-associated region:1-327(MINT-8431328) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96WV5 uniprotkb:P39656 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457|uniprotkb:B4DJE3|uniprotkb:B4DLI2 psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504027|mint:MINT-8431383|imex:IM-27961-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431396(identity) refseq:NP_005207.2|ensembl:ENSG00000244038(gene)|ensembl:ENST00000415136(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034097"(response to cytokine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042110"(T cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548|mint:MINT-8431386(identity) - comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins - figure legend:f2g|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.9x10^-6(molar) 2013/05/20 2020/05/07 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606 intact-crc:E167A325B121B012|rigid:Q0c3vicoIty+SCi7ss3AkHbepHk false his tag:?-?(MINT-8431397)|binding-associated region:1-327(MINT-8431399) binding-associated region:451-456(MINT-8431387) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q96WV5 uniprotkb:P33767 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" intact:EBI-12658|uniprotkb:D3DLP5|ensemblfungi:YEL002C psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:ostb_yeast(display_long)|uniprotkb:WBP1(gene name)|psi-mi:WBP1(display_short)|uniprotkb:Oligosaccharyl transferase subunit beta(gene name synonym)|uniprotkb:YEL002C(locus name) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504007|mint:MINT-8431363|imex:IM-27961-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431370(identity) ensemblfungi:YEL002C(gene)|ensemblfungi:YEL002C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|rcsb pdb:4J86|rcsb pdb:6C26|rcsb pdb:6EZN|reactome:R-SCE-6798695|refseq:NP_010914.3|sgd:S000000728|mint:P33767|dip:DIP-676N|mint:MINT-8431366(identity) - comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins crc64:495DA76BE8A9B29A figure legend:f2e|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:36.6x10^-6(molar) 2013/05/20 2020/05/07 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 rogid:hSnp48laqjCzA32hSJblrQ/5q5E559292 intact-crc:F624C979F325C3F4|rigid:agTCezfsPSfBhsGysgiZWssOXTA false binding-associated region:1-327(MINT-8431371)|his tag:?-?(MINT-8431373) binding-associated region:425-430(MINT-8431367) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q96WV5 uniprotkb:P68978 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" intact:EBI-4407041|uniprotkb:P03251 psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:e3gl_ade02(display_long)|uniprotkb:E3-19K(gene name synonym)|uniprotkb:E3gp 19 kDa(gene name synonym)|uniprotkb:GP19K(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:10515(ade02)|taxid:10515("Human adenovirus C serotype 2 (HAdV-2)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8503987|mint:MINT-8431344|imex:IM-27961-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431357(identity) refseq:AP_000184.1|refseq:NP_040531.1|interpro:IPR006965(Adenovirus GP19K)|interpro:IPR038710|go:"GO:0005537"(mannose binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039591"|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|mint:MINT-8431347(identity) - comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins - figure legend:f2e|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:64.5x10^-6(molar) 2013/05/20 2014/10/16 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 rogid:XJsAfLwKM8ClP2oC6/tkRHrf1Zk10515 intact-crc:5549FF2E947CA395|rigid:pGyYOsNHFYKybsdvfsOHuXQ22aE false binding-associated region:1-327(MINT-8431360)|his tag:?-?(MINT-8431358) binding-associated region:148-159(MINT-8431348) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P53622 uniprotkb:P41811 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504067|mint:MINT-8431466|imex:IM-27961-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431469(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431475(identity) - crc64:D3589073106F5570 crc64:6A5E50BBEB02CB58 figure legend:f4c|comment:homomint|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:44.2x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:7D816077ED6F33C8|rigid:uogh/FsMaj7DmUjoVUFVa8fVzwA false his tag:?-?(MINT-8431472)|binding-associated region:624-818(MINT-8431470) his tag:?-?(MINT-8431476)|binding-associated region:1-814(MINT-8431478) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 uniprotkb:Q9Y5U4 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-8503746|intact:MINT-8431157|uniprotkb:Q8TBI8|uniprotkb:A8K5W8|ensembl:ENSP00000245787 psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:insi2_human(display_long)|uniprotkb:INSIG2(gene name)|psi-mi:INSIG2(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504067|mint:MINT-8431466|imex:IM-27961-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431469(identity) refseq:NP_001308259.1|refseq:NP_001308260.1|refseq:NP_001308261.1|refseq:NP_001308262.1|refseq:NP_001308258.1|refseq:NP_057217.2|dip:DIP-60913N|ensembl:ENSG00000125629(gene)|ensembl:ENST00000245787(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0010894"(negative regulation of steroid biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032937"(SREBP-SCAP-Insig complex)|go:"GO:0036316"(SREBP-SCAP complex retention in endoplasmic reticulum)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:0070542"(response to fatty acid)|interpro:IPR025929|rcsb pdb:4J82|rcsb pdb:6M49|rcsb pdb:7ETW|reactome:R-HSA-1655829|mint:MINT-8431481(identity) - crc64:D3589073106F5570 comment:mint|comment:homomint figure legend:f4c|comment:homomint|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:44.2x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:u6hydxrFnhRfWQ4LuogzQ+P/S1I9606 intact-crc:7D816077ED6F33C8|rigid:uogh/FsMaj7DmUjoVUFVa8fVzwA false his tag:?-?(MINT-8431472)|binding-associated region:624-818(MINT-8431470) binding-associated region:218-225(MINT-8431482) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q96WV5 intact:EBI-8503574 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" intact:MINT-8430971 psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:a0a3f3ey22_yeasa(display_short)|psi-mi:EBI-8503574(display_long)|uniprotkb:AWRI796_1468(orf name) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:764097(yeasa)|taxid:764097("Saccharomyces cerevisiae (strain AWRI796)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504047|mint:MINT-8431405|imex:IM-27961-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431413(identity) uniprotkb:A0A3F3EY22(uniprot-removed-ac)|mint:MINT-8431409(identity) - comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.|comment:mint figure legend:f2g|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:16.1x10^-6(molar) 2013/05/20 2014/10/16 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 rogid:lLKyvNDfngKfVQ7idM4VteCNrt4764097 intact-crc:C2C5C8467FF80A3D|rigid:c6LRKVgfoGt8uTHy7FWYDE1Q/WE false binding-associated region:1-327(MINT-8431414)|his tag:?-?(MINT-8431416) binding-associated region:440-445(MINT-8431410) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P53622 uniprotkb:P41811 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504127|mint:MINT-8431505|imex:IM-27961-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431512(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431518(identity) - crc64:D3589073106F5570 crc64:6A5E50BBEB02CB58 figure legend:f4c|comment:homomint|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2014/10/16 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:0C9605E87C825785|rigid:1JJqiIMX0jO22q36YkDY4nbbEII false his tag:?-?(MINT-8431515)|binding-associated region:624-818(MINT-8431513) his tag:?-?(MINT-8431519)|binding-associated region:1-814(MINT-8431521) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 uniprotkb:Q91AV1 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-8503634|intact:MINT-8431061 psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:spike_pedv7(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:229032(pedv)|taxid:229032("Porcine epidemic diarrhea virus (strain CV777)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504127|mint:MINT-8431505|imex:IM-27961-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431512(identity) interpro:IPR042552|interpro:IPR043607|interpro:IPR043614|interpro:IPR002552(Coronavirus S2 glycoprotein)|refseq:NP_598310.1|interpro:IPR002551(Coronavirus S1 glycoprotein)|rcsb pdb:4J79|rcsb pdb:6U7K|interpro:IPR043473|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR044873|interpro:IPR044874|mint:MINT-8431508(identity) - crc64:D3589073106F5570 comment:mint|comment:homomint figure legend:f4c|comment:homomint|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2014/10/16 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:GsfcvtFlfI19W4JisYC7vFmdhek229032 intact-crc:0C9605E87C825785|rigid:1JJqiIMX0jO22q36YkDY4nbbEII false his tag:?-?(MINT-8431515)|binding-associated region:624-818(MINT-8431513) binding-associated region:1377-1383(MINT-8431509) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P53622 uniprotkb:P41811 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504097|mint:MINT-8431486|imex:IM-27961-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431499(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431493(identity) - crc64:D3589073106F5570 crc64:6A5E50BBEB02CB58 figure legend:f4c|comment:homomint|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:31.9x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:6887CE4735F8584F|rigid:HuKFRzsGmZU6s+iBVg3XNEHJ1q8 false binding-associated region:624-818(MINT-8431502)|his tag:?-?(MINT-8431500) binding-associated region:1-814(MINT-8431494)|his tag:?-?(MINT-8431496) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 uniprotkb:O15503 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-6252425|ensembl:ENSP00000344741|uniprotkb:A8K6L0|uniprotkb:Q53XW8|uniprotkb:Q9BUV5|uniprotkb:A4D2N1 psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:insi1_human(display_long)|uniprotkb:INSIG1(gene name)|psi-mi:INSIG1(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504097|mint:MINT-8431486|imex:IM-27961-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431499(identity) ensembl:ENSG00000186480(gene)|ensembl:ENST00000340368(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0010894"(negative regulation of steroid biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032937"(SREBP-SCAP-Insig complex)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0036316"(SREBP-SCAP complex retention in endoplasmic reticulum)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:1901303"(negative regulation of cargo loading into COPII-coated vesicle)|interpro:IPR009904(Insulin-induced)|interpro:IPR025929|mint:O15503|rcsb pdb:4J81|reactome:R-HSA-1655829|go:"GO:0070862"(negative regulation of protein exit from endoplasmic reticulum)|refseq:NP_001333519.1|refseq:NP_001333520.1|refseq:NP_001333521.1|refseq:NP_001333522.1|refseq:NP_001333523.1|refseq:NP_005533.2|refseq:NP_938150.2|refseq:NP_938151.1|dip:DIP-61157N|refseq:XP_016867666.1|mint:MINT-8431489(identity) - crc64:D3589073106F5570 - figure legend:f4c|comment:homomint|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:31.9x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:CePNtn7b6ienEbjTcmzRblg0FnE9606 intact-crc:6887CE4735F8584F|rigid:HuKFRzsGmZU6s+iBVg3XNEHJ1q8 false binding-associated region:624-818(MINT-8431502)|his tag:?-?(MINT-8431500) binding-associated region:272-277(MINT-8431490) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q96WV5 uniprotkb:Q9Y5U4 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" intact:EBI-8503746|intact:MINT-8431157|uniprotkb:Q8TBI8|uniprotkb:A8K5W8|ensembl:ENSP00000245787 psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:insi2_human(display_long)|uniprotkb:INSIG2(gene name)|psi-mi:INSIG2(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504156|mint:MINT-8431525|imex:IM-27961-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431528(identity) refseq:NP_001308259.1|refseq:NP_001308260.1|refseq:NP_001308261.1|refseq:NP_001308262.1|refseq:NP_001308258.1|refseq:NP_057217.2|dip:DIP-60913N|ensembl:ENSG00000125629(gene)|ensembl:ENST00000245787(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0010894"(negative regulation of steroid biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032937"(SREBP-SCAP-Insig complex)|go:"GO:0036316"(SREBP-SCAP complex retention in endoplasmic reticulum)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:0070542"(response to fatty acid)|interpro:IPR025929|rcsb pdb:4J82|rcsb pdb:6M49|rcsb pdb:7ETW|reactome:R-HSA-1655829|mint:MINT-8431534(identity) - comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins comment:mint|comment:homomint figure legend:f4c|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:22.7x10^-6(molar) 2013/05/20 2020/05/07 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 rogid:u6hydxrFnhRfWQ4LuogzQ+P/S1I9606 intact-crc:AC826125D5F52679|rigid:71pR4VUsDaE7oDejVboQd2WVAho false binding-associated region:1-327(MINT-8431531)|his tag:?-?(MINT-8431529) binding-associated region:218-225(MINT-8431535) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q96WV5 uniprotkb:O15503 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" intact:EBI-6252425|ensembl:ENSP00000344741|uniprotkb:A8K6L0|uniprotkb:Q53XW8|uniprotkb:Q9BUV5|uniprotkb:A4D2N1 psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:insi1_human(display_long)|uniprotkb:INSIG1(gene name)|psi-mi:INSIG1(display_short) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504176|mint:MINT-8431539|imex:IM-27961-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431542(identity) ensembl:ENSG00000186480(gene)|ensembl:ENST00000340368(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0010894"(negative regulation of steroid biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032937"(SREBP-SCAP-Insig complex)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0036316"(SREBP-SCAP complex retention in endoplasmic reticulum)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060363"(cranial suture morphogenesis)|go:"GO:1901303"(negative regulation of cargo loading into COPII-coated vesicle)|interpro:IPR009904(Insulin-induced)|interpro:IPR025929|mint:O15503|rcsb pdb:4J81|reactome:R-HSA-1655829|go:"GO:0070862"(negative regulation of protein exit from endoplasmic reticulum)|refseq:NP_001333519.1|refseq:NP_001333520.1|refseq:NP_001333521.1|refseq:NP_001333522.1|refseq:NP_001333523.1|refseq:NP_005533.2|refseq:NP_938150.2|refseq:NP_938151.1|dip:DIP-61157N|refseq:XP_016867666.1|mint:MINT-8431548(identity) - comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins - figure legend:f4c|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:27.9x10^-6(molar) 2013/05/20 2020/05/07 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 rogid:CePNtn7b6ienEbjTcmzRblg0FnE9606 intact-crc:48B57DB7271DD65B|rigid:xZ7NCgf8HIZsfVQwncfhtEuvIIE false his tag:?-?(MINT-8431545)|binding-associated region:1-327(MINT-8431543) binding-associated region:272-277(MINT-8431549) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q91AV1 uniprotkb:Q96WV5 intact:EBI-8503634|intact:MINT-8431061 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" psi-mi:spike_pedv7(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:229032(pedv)|taxid:229032("Porcine epidemic diarrhea virus (strain CV777)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504196|mint:MINT-8431552|imex:IM-27961-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR042552|interpro:IPR043607|interpro:IPR043614|interpro:IPR002552(Coronavirus S2 glycoprotein)|refseq:NP_598310.1|interpro:IPR002551(Coronavirus S1 glycoprotein)|rcsb pdb:4J79|rcsb pdb:6U7K|interpro:IPR043473|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR044873|interpro:IPR044874|mint:MINT-8431561(identity) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431555(identity) - comment:mint|comment:homomint comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins figure legend:f4c|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:81.9x10^-6(molar) 2013/05/20 2020/05/07 rogid:GsfcvtFlfI19W4JisYC7vFmdhek229032 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 intact-crc:A963BCD88982D898|rigid:SZ0I0rYNLrpCnpd0jOrokVjvHds false binding-associated region:1377-1383(MINT-8431562) binding-associated region:1-327(MINT-8431558)|his tag:?-?(MINT-8431556) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) intact:EBI-8504221 uniprotkb:Q96WV5 intact:MINT-8431655 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" psi-mi:kkyl motif(display_short)|psi-mi:EBI-8504221(display_long) psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504216|mint:MINT-8431629|imex:IM-27961-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) mint:MINT-8431657(identity) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431636(identity) - comment:mint|no-uniprot-update: comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins figure legend:f7b|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:21.3x10^-6(molar) 2013/05/20 2020/05/07 rogid:7RBuObW8tV65ZHHLI8+5MLiHfic-2 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 intact-crc:FE30F534253FE026|rigid:W4TaIhUdFWiPgYuFnjoeDDcjfgw false - binding-associated region:1-327(MINT-8431637)|his tag:?-?(MINT-8431639) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96WV5 intact:EBI-8504238 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" intact:MINT-8431674 psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:kkaa motif(display_short)|psi-mi:EBI-8504238(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504243|mint:MINT-8431661|imex:IM-27961-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431666(identity) mint:MINT-8431676(identity) - comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins comment:mint|no-uniprot-update: figure legend:f7b|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:51.7x10^-6(molar) 2013/05/20 2020/05/07 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 rogid:z1lEhjS5l6jd/erkVBg1mCendg8-2 intact-crc:063DF00C7DD414B2|rigid:1lZh0hzU/ydwsvHMBLxBDtYxqww false his tag:?-?(MINT-8431667)|binding-associated region:1-327(MINT-8431669) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q96WV5 intact:EBI-8503611 intact:EBI-8503699|intact:MINT-4701710|ensemblfungi:"SPBPJ4664.04.1:pep" intact:MINT-8431037 psi-mi:copa_schpo(display_long)|uniprotkb:SPBPJ4664.04(orf name)|uniprotkb:Alpha-coat protein(gene name synonym) psi-mi:scyl1(display_short)|psi-mi:EBI-8503611(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504267|mint:MINT-8431680|imex:IM-27961-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) reactome:R-SPO-6811434|interpro:IPR016391(Coatomer, alpha subunit)|rcsb pdb:4J87|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:4J8B|refseq:NP_595279.1|interpro:IPR020472|rcsb pdb:4J8G|interpro:IPR019775|reactome:R-SPO-6807878|interpro:IPR036322|ensemblfungi:SPBPJ4664.04(gene)|ensemblfungi:SPBPJ4664.04.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|mint:MINT-8431685(identity) mint:MINT-8431695(identity) - comment:mint|function:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins comment:mint|no-uniprot-update: figure legend:f5c|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2020/05/07 rogid:pWFard6eVzf+7sA5pggpAbA4KtM284812 rogid:i2sWLOTBA5/GAcia1akBtsLdgfI-2 intact-crc:E8FEEBA5F747DA1A|rigid:cXsxgX5xmtugG361PGxH9TbPHzo false binding-associated region:1-327(MINT-8431686)|his tag:?-?(MINT-8431688) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P53622 uniprotkb:P41811 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504307|mint:MINT-8431699|imex:IM-27961-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431703(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431710(identity) - crc64:D3589073106F5570 crc64:6A5E50BBEB02CB58 figure legend:f5c|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:20.4x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:90BBF3BF86BA70DE|rigid:E8hAvJXEd04My4kF+b56WCxmCaQ false his tag:?-?(MINT-8431704)|binding-associated region:624-818(MINT-8431706) his tag:?-?(MINT-8431715) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 intact:EBI-8503611 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:MINT-8431037 psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:scyl1(display_short)|psi-mi:EBI-8503611(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504307|mint:MINT-8431699|imex:IM-27961-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431703(identity) mint:MINT-8431701(identity) - crc64:D3589073106F5570 comment:mint|no-uniprot-update: figure legend:f5c|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:20.4x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:i2sWLOTBA5/GAcia1akBtsLdgfI-2 intact-crc:90BBF3BF86BA70DE|rigid:E8hAvJXEd04My4kF+b56WCxmCaQ false his tag:?-?(MINT-8431704)|binding-associated region:624-818(MINT-8431706) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P53622 uniprotkb:P41811 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504335|mint:MINT-8431729|imex:IM-27961-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431732(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431738(identity) - crc64:D3589073106F5570 crc64:6A5E50BBEB02CB58 figure legend:f5c|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:80.0x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:57F11E89CFA831F3|rigid:QBkiefh97ZeDeGyAXQFeLgplaQM false his tag:?-?(MINT-8431735)|binding-associated region:624-818(MINT-8431733) his tag:?-?(MINT-8431739) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 intact:EBI-8504330 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:MINT-8431746 psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:"scyl1 (akld)"(display_short)|psi-mi:EBI-8504330(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504335|mint:MINT-8431729|imex:IM-27961-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431732(identity) mint:MINT-8431748(identity) - crc64:D3589073106F5570 comment:mint|no-uniprot-update: figure legend:f5c|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:80.0x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:oqE1eQuTKIEHNYdMGqnqCGt919o-2 intact-crc:57F11E89CFA831F3|rigid:QBkiefh97ZeDeGyAXQFeLgplaQM false his tag:?-?(MINT-8431735)|binding-associated region:624-818(MINT-8431733) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P53622 uniprotkb:P41811 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504400|mint:MINT-8431752|imex:IM-27961-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431761(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431757(identity) - crc64:D3589073106F5570 crc64:6A5E50BBEB02CB58 figure legend:f5c|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:89.1x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:BBB2B1B68C5279C0|rigid:rv8pGis+Ld1AQLDdQ+CI9DlflqE false binding-associated region:624-818(MINT-8431764)|his tag:?-?(MINT-8431762) his tag:?-?(MINT-8431758) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 intact:EBI-8504395 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:MINT-8431769 psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:"scyl1(krld)"(display_short)|psi-mi:EBI-8504395(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504400|mint:MINT-8431752|imex:IM-27961-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431761(identity) mint:MINT-8431771(identity) - crc64:D3589073106F5570 comment:mint|no-uniprot-update: figure legend:f5c|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:89.1x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:TLEoKAnfZ1riHv7n7bP7GmLsDw8-2 intact-crc:BBB2B1B68C5279C0|rigid:rv8pGis+Ld1AQLDdQ+CI9DlflqE false binding-associated region:624-818(MINT-8431764)|his tag:?-?(MINT-8431762) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P53622 uniprotkb:P41811 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504423|mint:MINT-8431775|imex:IM-27961-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431780(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431786(identity) - crc64:D3589073106F5570 crc64:6A5E50BBEB02CB58 figure legend:f7b|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:34.5x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:079059DE18540107|rigid:fmzawEgcdcvsQd060ho09XiCalc false binding-associated region:624-818(MINT-8431781)|his tag:?-?(MINT-8431783) his tag:?-?(MINT-8431787) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 intact:EBI-8504221 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:MINT-8431655 psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:kkyl motif(display_short)|psi-mi:EBI-8504221(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504423|mint:MINT-8431775|imex:IM-27961-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431780(identity) mint:MINT-8431794(identity) - crc64:D3589073106F5570 comment:mint|no-uniprot-update: figure legend:f7b|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:34.5x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:7RBuObW8tV65ZHHLI8+5MLiHfic-2 intact-crc:079059DE18540107|rigid:fmzawEgcdcvsQd060ho09XiCalc false binding-associated region:624-818(MINT-8431781)|his tag:?-?(MINT-8431783) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P53622 uniprotkb:P41811 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504446|mint:MINT-8431798|imex:IM-27961-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431807(identity) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431803(identity) - crc64:D3589073106F5570 crc64:6A5E50BBEB02CB58 figure legend:f7b|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:50.8x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 intact-crc:B37F92CBA0272771|rigid:QlTsYJ0OWAPHuhzkY9nL4DBTz+A false his tag:?-?(MINT-8431808)|binding-associated region:624-818(MINT-8431810) his tag:?-?(MINT-8431804) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53622 intact:EBI-8504238 intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C intact:MINT-8431674 psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:kkaa motif(display_short)|psi-mi:EBI-8504238(display_long) psi-mi:"MI:0065"(isothermal titration calorimetry) Ma et al. (2013) pubmed:23481256|mint:MINT-8430851|imex:IM-27961 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8504446|mint:MINT-8431798|imex:IM-27961-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434|mint:MINT-8431807(identity) mint:MINT-8431818(identity) - crc64:D3589073106F5570 comment:mint|no-uniprot-update: figure legend:f7b|comment:mint|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:50.8x10^-6(molar) 2013/05/20 2020/05/07 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 rogid:z1lEhjS5l6jd/erkVBg1mCendg8-2 intact-crc:B37F92CBA0272771|rigid:QlTsYJ0OWAPHuhzkY9nL4DBTz+A false his tag:?-?(MINT-8431808)|binding-associated region:624-818(MINT-8431810) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis)