#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P27361	uniprotkb:Q9EPI6	intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025	intact:EBI-6899705|uniprotkb:Q5PPF6|uniprotkb:Q7TSC6|uniprotkb:Q7TSC8|uniprotkb:Q9EPI4|uniprotkb:Q9EPI5	psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym)	psi-mi:nsmf_rat(display_long)|uniprotkb:Nsmf(gene name)|psi-mi:Nsmf(display_short)|uniprotkb:Jac(gene name synonym)|uniprotkb:Nelf(gene name synonym)|uniprotkb:Juxtasynaptic attractor of caldendrin on dendritic boutons protein(gene name synonym)|uniprotkb:Nasal embryonic luteinizing hormone-releasing hormone factor(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Karpova et al. (2013)	pubmed:23452857|imex:IM-20963	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6899704|imex:IM-20963-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)	go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0005886"(plasma membrane)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:0097440"(apical dendrite)|mint:Q9EPI6|interpro:IPR033374|rgd:619819|refseq:NP_001257555.1|refseq:NP_001257556.1|refseq:NP_001257557.1|refseq:NP_476538.2	-	-	-	comment:An increase in response was observed on addition of ATP, which promote the phosphorylation of Jacob by ERK1|agonist:ATP|figure legend:Fig. 1F, 1G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/23	2014/10/16	rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606	rogid:7roymdKtL+QSCC6O/qfhzsLvSaA10116	intact-crc:DB410F7A5505F44D|rigid:uwNTsXH50adiVJY840G55tUGbVM	false	N-phosphorylated residue:?-?|glutathione s tranferase tag:n-n	his tag:n-n|sufficient binding region:45-532|tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9EPI6	uniprotkb:P27361	intact:EBI-6899705|uniprotkb:Q5PPF6|uniprotkb:Q7TSC6|uniprotkb:Q7TSC8|uniprotkb:Q9EPI4|uniprotkb:Q9EPI5	intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025	psi-mi:nsmf_rat(display_long)|uniprotkb:Nsmf(gene name)|psi-mi:Nsmf(display_short)|uniprotkb:Jac(gene name synonym)|uniprotkb:Nelf(gene name synonym)|uniprotkb:Juxtasynaptic attractor of caldendrin on dendritic boutons protein(gene name synonym)|uniprotkb:Nasal embryonic luteinizing hormone-releasing hormone factor(gene name synonym)	psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Karpova et al. (2013)	pubmed:23452857|imex:IM-20963	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6899773|imex:IM-20963-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0005886"(plasma membrane)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:0097440"(apical dendrite)|mint:Q9EPI6|interpro:IPR033374|rgd:619819|refseq:NP_001257555.1|refseq:NP_001257556.1|refseq:NP_001257557.1|refseq:NP_476538.2	refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)	-	-	-	comment:a GST-Jacob fusion protein interacts more efficiently with active versus inactive ERK1.|figure legend:Fig. 1H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/23	2014/10/16	rogid:7roymdKtL+QSCC6O/qfhzsLvSaA10116	rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606	intact-crc:62FC5495A9EF5A67|rigid:uwNTsXH50adiVJY840G55tUGbVM	false	glutathione s tranferase tag:?-?|sufficient binding region:262-532	N-phosphorylated residue:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q99NF2	uniprotkb:P27361	intact:EBI-6899808|ensembl:ENSMUSP00000097908|uniprotkb:A2AJ93|uniprotkb:A2AJ94|uniprotkb:Q8BPT0|uniprotkb:Q8C9R5|uniprotkb:Q9DBF4|uniprotkb:Q9ERZ1	intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025	psi-mi:nsmf_mouse(display_long)|uniprotkb:Nsmf(gene name)|psi-mi:Nsmf(display_short)|uniprotkb:Jac(gene name synonym)|uniprotkb:Nelf(gene name synonym)|uniprotkb:Juxtasynaptic attractor of caldendrin on dendritic boutons protein(gene name synonym)|uniprotkb:Nasal embryonic luteinizing hormone-releasing hormone factor(gene name synonym)	psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Karpova et al. (2013)	pubmed:23452857|imex:IM-20963	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6899796|imex:IM-20963-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000006476(gene)|ensembl:ENSMUST00000100334(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR033374|refseq:NP_001034475.1|refseq:NP_001034476.1|refseq:NP_001171125.1|refseq:NP_001171126.1|refseq:NP_064672.2	refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	resulting-ptm:Ser180 and 181 are phosphorylated by ERK1|figure legend:Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/23	2014/10/16	rogid:H2he+8bW41RalDgx0Ds8nQE1cDU10090	rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606	intact-crc:F01A30A7D38BBE7E|rigid:e7acvTFFNnksfJSgKzmGecqgVQg	false	sufficient binding region:45-532|his tag:n-n|tag:n-n	N-phosphorylated residue:?-?	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9EPI6	uniprotkb:P23565	intact:EBI-6899705|uniprotkb:Q5PPF6|uniprotkb:Q7TSC6|uniprotkb:Q7TSC8|uniprotkb:Q9EPI4|uniprotkb:Q9EPI5	intact:EBI-6899875	psi-mi:nsmf_rat(display_long)|uniprotkb:Nsmf(gene name)|psi-mi:Nsmf(display_short)|uniprotkb:Jac(gene name synonym)|uniprotkb:Nelf(gene name synonym)|uniprotkb:Juxtasynaptic attractor of caldendrin on dendritic boutons protein(gene name synonym)|uniprotkb:Nasal embryonic luteinizing hormone-releasing hormone factor(gene name synonym)	psi-mi:ainx_rat(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:Inexa(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Karpova et al. (2013)	pubmed:23452857|imex:IM-20963	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6899892|imex:IM-20963-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0005886"(plasma membrane)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:0097440"(apical dendrite)|mint:Q9EPI6|interpro:IPR033374|rgd:619819|refseq:NP_001257555.1|refseq:NP_001257556.1|refseq:NP_001257557.1|refseq:NP_476538.2	go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042246"(tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|rgd:2911|mint:P23565|interpro:IPR027703|interpro:IPR039008	-	-	-	figure legend:Supp. Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/07/23	2014/10/16	rogid:7roymdKtL+QSCC6O/qfhzsLvSaA10116	rogid:4qBkIm9ifAEYegj00H2EUgBCn0w10116	intact-crc:1DCA32064EE86266|rigid:Ei77UOh29C8bVGpwNKMjJrtVOJg	false	sufficient binding region:262-532|sufficient binding region:1-228	necessary binding region:408-442	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23565	uniprotkb:Q9EPI6	intact:EBI-6899875	intact:EBI-6899705|uniprotkb:Q5PPF6|uniprotkb:Q7TSC6|uniprotkb:Q7TSC8|uniprotkb:Q9EPI4|uniprotkb:Q9EPI5	psi-mi:ainx_rat(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:Inexa(gene name synonym)	psi-mi:nsmf_rat(display_long)|uniprotkb:Nsmf(gene name)|psi-mi:Nsmf(display_short)|uniprotkb:Jac(gene name synonym)|uniprotkb:Nelf(gene name synonym)|uniprotkb:Juxtasynaptic attractor of caldendrin on dendritic boutons protein(gene name synonym)|uniprotkb:Nasal embryonic luteinizing hormone-releasing hormone factor(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Karpova et al. (2013)	pubmed:23452857|imex:IM-20963	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6899920|imex:IM-20963-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042246"(tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|rgd:2911|mint:P23565|interpro:IPR027703|interpro:IPR039008	go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0005886"(plasma membrane)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:0097440"(apical dendrite)|mint:Q9EPI6|interpro:IPR033374|rgd:619819|refseq:NP_001257555.1|refseq:NP_001257556.1|refseq:NP_001257557.1|refseq:NP_476538.2	-	-	-	figure legend:Supp. Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2013/07/23	2014/10/16	rogid:4qBkIm9ifAEYegj00H2EUgBCn0w10116	rogid:7roymdKtL+QSCC6O/qfhzsLvSaA10116	intact-crc:838DD0E56B05BACE|rigid:Ei77UOh29C8bVGpwNKMjJrtVOJg	false	sufficient binding region:1-465	sufficient binding region:167-228	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9EPI6	uniprotkb:P23565	intact:EBI-6899705|uniprotkb:Q5PPF6|uniprotkb:Q7TSC6|uniprotkb:Q7TSC8|uniprotkb:Q9EPI4|uniprotkb:Q9EPI5	intact:EBI-6899875	psi-mi:nsmf_rat(display_long)|uniprotkb:Nsmf(gene name)|psi-mi:Nsmf(display_short)|uniprotkb:Jac(gene name synonym)|uniprotkb:Nelf(gene name synonym)|uniprotkb:Juxtasynaptic attractor of caldendrin on dendritic boutons protein(gene name synonym)|uniprotkb:Nasal embryonic luteinizing hormone-releasing hormone factor(gene name synonym)	psi-mi:ainx_rat(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:Inexa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Karpova et al. (2013)	pubmed:23452857|imex:IM-20963	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6899956|imex:IM-20963-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0005886"(plasma membrane)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:0097440"(apical dendrite)|mint:Q9EPI6|interpro:IPR033374|rgd:619819|refseq:NP_001257555.1|refseq:NP_001257556.1|refseq:NP_001257557.1|refseq:NP_476538.2	go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042246"(tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|rgd:2911|mint:P23565|interpro:IPR027703|interpro:IPR039008	-	-	-	figure legend:Supp. Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/23	2014/10/16	rogid:7roymdKtL+QSCC6O/qfhzsLvSaA10116	rogid:4qBkIm9ifAEYegj00H2EUgBCn0w10116	intact-crc:C2C4F20281D201D6|rigid:Ei77UOh29C8bVGpwNKMjJrtVOJg	false	myc tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9EPI6	uniprotkb:P23565	intact:EBI-6899705|uniprotkb:Q5PPF6|uniprotkb:Q7TSC6|uniprotkb:Q7TSC8|uniprotkb:Q9EPI4|uniprotkb:Q9EPI5	intact:EBI-6899875	psi-mi:nsmf_rat(display_long)|uniprotkb:Nsmf(gene name)|psi-mi:Nsmf(display_short)|uniprotkb:Jac(gene name synonym)|uniprotkb:Nelf(gene name synonym)|uniprotkb:Juxtasynaptic attractor of caldendrin on dendritic boutons protein(gene name synonym)|uniprotkb:Nasal embryonic luteinizing hormone-releasing hormone factor(gene name synonym)	psi-mi:ainx_rat(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:Inexa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Karpova et al. (2013)	pubmed:23452857|imex:IM-20963	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6899974|imex:IM-20963-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0005886"(plasma membrane)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:0097440"(apical dendrite)|mint:Q9EPI6|interpro:IPR033374|rgd:619819|refseq:NP_001257555.1|refseq:NP_001257556.1|refseq:NP_001257557.1|refseq:NP_476538.2	go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042246"(tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|rgd:2911|mint:P23565|interpro:IPR027703|interpro:IPR039008	-	-	-	figure legend:Supp. Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/23	2014/10/16	rogid:7roymdKtL+QSCC6O/qfhzsLvSaA10116	rogid:4qBkIm9ifAEYegj00H2EUgBCn0w10116	intact-crc:4919D2FBF4E4ED5F|rigid:Ei77UOh29C8bVGpwNKMjJrtVOJg	false	sufficient binding region:45-280|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23565	uniprotkb:P83953	intact:EBI-6899875	intact:EBI-6899992	psi-mi:ainx_rat(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:Inexa(gene name synonym)	psi-mi:ima5_rat(display_long)|uniprotkb:Kpna1(gene name)|psi-mi:Kpna1(display_short)|uniprotkb:Importin alpha-5(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Karpova et al. (2013)	pubmed:23452857|imex:IM-20963	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6900011|imex:IM-20963-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042246"(tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|rgd:2911|mint:P23565|interpro:IPR027703|interpro:IPR039008	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014841"(skeletal muscle satellite cell proliferation)|go:"GO:0014901"(satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030425"(dendrite)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|reactome:R-RNO-909733|rgd:735064|dip:DIP-46060N|reactome:R-RNO-140342	-	-	-	figure legend:Fig. 4A|comment:Erk1/2 also present in the immunoprecipitate.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2013/07/23	2014/10/16	rogid:4qBkIm9ifAEYegj00H2EUgBCn0w10116	rogid:aFowdROlvuNihzkUTAIqh0HAWqM10116	intact-crc:31AD8F08A0D55973|rigid:HDtTYW6Bm5B116ppIIbzDk6/Jpc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23565	uniprotkb:Q9EPI6	intact:EBI-6899875	intact:EBI-6899705|uniprotkb:Q5PPF6|uniprotkb:Q7TSC6|uniprotkb:Q7TSC8|uniprotkb:Q9EPI4|uniprotkb:Q9EPI5	psi-mi:ainx_rat(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:Inexa(gene name synonym)	psi-mi:nsmf_rat(display_long)|uniprotkb:Nsmf(gene name)|psi-mi:Nsmf(display_short)|uniprotkb:Jac(gene name synonym)|uniprotkb:Nelf(gene name synonym)|uniprotkb:Juxtasynaptic attractor of caldendrin on dendritic boutons protein(gene name synonym)|uniprotkb:Nasal embryonic luteinizing hormone-releasing hormone factor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Karpova et al. (2013)	pubmed:23452857|imex:IM-20963	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6900011|imex:IM-20963-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042246"(tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|rgd:2911|mint:P23565|interpro:IPR027703|interpro:IPR039008	go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0005886"(plasma membrane)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:0097440"(apical dendrite)|mint:Q9EPI6|interpro:IPR033374|rgd:619819|refseq:NP_001257555.1|refseq:NP_001257556.1|refseq:NP_001257557.1|refseq:NP_476538.2	-	-	-	figure legend:Fig. 4A|comment:Erk1/2 also present in the immunoprecipitate.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2013/07/23	2014/10/16	rogid:4qBkIm9ifAEYegj00H2EUgBCn0w10116	rogid:7roymdKtL+QSCC6O/qfhzsLvSaA10116	intact-crc:31AD8F08A0D55973|rigid:HDtTYW6Bm5B116ppIIbzDk6/Jpc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)