#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P97784 uniprotkb:Q8C4V4 intact:EBI-1266607|ensembl:ENSMUSP00000020227 intact:EBI-1266589|uniprotkb:Q80V32|uniprotkb:Q8K1W0|uniprotkb:Q9QXW1|ensembl:ENSMUSP00000022720|ensembl:ENSMUSP00000116044 psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short) psi-mi:fbxl3_mouse(display_long)|uniprotkb:Afh(gene name synonym)|uniprotkb:Ovtm(gene name synonym)|uniprotkb:Protein after-hours(gene name synonym)|uniprotkb:Protein overtime(gene name synonym)|uniprotkb:Fbxl3(gene name)|psi-mi:Fbxl3(display_short)|uniprotkb:Fbl3a(gene name synonym)|uniprotkb:Fbxl3a(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899449|imex:IM-20960-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm) refseq:NP_056637.1|refseq:XP_006519302.1|refseq:XP_006519303.1|refseq:XP_006519304.1|ensembl:ENSMUSG00000022124(gene)|ensembl:ENSMUST00000022720(transcript)|ensembl:ENSMUST00000145693(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090 rogid:X6zalZ4TQNZRr3LdC2Rw9hKRIW810090 intact-crc:5D818DB4B79E5C39|rigid:pbEx5mzbsrMQpWrr/MkQ7q+oukU false myc tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BFZ4 uniprotkb:Q9R194 intact:EBI-6898235|ensembl:ENSMUSP00000035248|uniprotkb:B2RSN8|uniprotkb:Q8BIJ8|uniprotkb:Q8BIW5 intact:EBI-1266619|uniprotkb:O08706|uniprotkb:Q6A024|ensembl:ENSMUSP00000088047|ensembl:ENSMUSP00000106909 psi-mi:fxl21_mouse(display_long)|uniprotkb:Fbxl21(gene name)|psi-mi:Fbxl21(display_short)|uniprotkb:Fbl21(gene name synonym)|uniprotkb:Fbxl3b(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 21(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3B(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3B(gene name synonym) psi-mi:cry2_mouse(display_long)|uniprotkb:Cry2(gene name)|psi-mi:Cry2(display_short)|uniprotkb:Kiaa0658(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899441|imex:IM-20960-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333661.1|ensembl:ENSMUSG00000035509(gene)|ensembl:ENSMUST00000045428(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_848789.2 refseq:NP_034093.1|refseq:XP_017170770.1|dip:DIP-38517N|ensembl:ENSMUSG00000068742(gene)|ensembl:ENSMUST00000090559(transcript)|ensembl:ENSMUST00000111278(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071949"(FAD binding)|go:"GO:2000118"(regulation of sodium-dependent phosphate transport)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:Q9R194|rcsb pdb:4I6E|rcsb pdb:4I6G|rcsb pdb:4I6J|rcsb pdb:4MLP|rcsb pdb:4U8H|rcsb pdb:6KX8|rcsb pdb:7D0N|rcsb pdb:7EJ9 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:Jpfnj3lalb7I39q60IfhdDnLIfA10090 rogid:00SKIwCL33BKjjyPSsxZUR5Sjbs10090 intact-crc:C9F5FE2C57093220|rigid:RVX+PfWYqPpeZYDLOuaK8TOQZN0 false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9R194 uniprotkb:Q8C4V4 intact:EBI-1266619|uniprotkb:O08706|uniprotkb:Q6A024|ensembl:ENSMUSP00000088047|ensembl:ENSMUSP00000106909 intact:EBI-1266589|uniprotkb:Q80V32|uniprotkb:Q8K1W0|uniprotkb:Q9QXW1|ensembl:ENSMUSP00000022720|ensembl:ENSMUSP00000116044 psi-mi:cry2_mouse(display_long)|uniprotkb:Cry2(gene name)|psi-mi:Cry2(display_short)|uniprotkb:Kiaa0658(gene name synonym) psi-mi:fbxl3_mouse(display_long)|uniprotkb:Afh(gene name synonym)|uniprotkb:Ovtm(gene name synonym)|uniprotkb:Protein after-hours(gene name synonym)|uniprotkb:Protein overtime(gene name synonym)|uniprotkb:Fbxl3(gene name)|psi-mi:Fbxl3(display_short)|uniprotkb:Fbl3a(gene name synonym)|uniprotkb:Fbxl3a(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899409|imex:IM-20960-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034093.1|refseq:XP_017170770.1|dip:DIP-38517N|ensembl:ENSMUSG00000068742(gene)|ensembl:ENSMUST00000090559(transcript)|ensembl:ENSMUST00000111278(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071949"(FAD binding)|go:"GO:2000118"(regulation of sodium-dependent phosphate transport)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:Q9R194|rcsb pdb:4I6E|rcsb pdb:4I6G|rcsb pdb:4I6J|rcsb pdb:4MLP|rcsb pdb:4U8H|rcsb pdb:6KX8|rcsb pdb:7D0N|rcsb pdb:7EJ9 refseq:NP_056637.1|refseq:XP_006519302.1|refseq:XP_006519303.1|refseq:XP_006519304.1|ensembl:ENSMUSG00000022124(gene)|ensembl:ENSMUST00000022720(transcript)|ensembl:ENSMUST00000145693(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168 - - - figure legend:Fig 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:00SKIwCL33BKjjyPSsxZUR5Sjbs10090 rogid:X6zalZ4TQNZRr3LdC2Rw9hKRIW810090 intact-crc:D451996EEB957CDF|rigid:r4XnBehfqTLqc0QsXOX0+fmTObY false myc tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8C4V4 uniprotkb:O54943 intact:EBI-1266589|uniprotkb:Q80V32|uniprotkb:Q8K1W0|uniprotkb:Q9QXW1|ensembl:ENSMUSP00000022720|ensembl:ENSMUSP00000116044 intact:EBI-1266779|uniprotkb:O54954 psi-mi:fbxl3_mouse(display_long)|uniprotkb:Afh(gene name synonym)|uniprotkb:Ovtm(gene name synonym)|uniprotkb:Protein after-hours(gene name synonym)|uniprotkb:Protein overtime(gene name synonym)|uniprotkb:Fbxl3(gene name)|psi-mi:Fbxl3(display_short)|uniprotkb:Fbl3a(gene name synonym)|uniprotkb:Fbxl3a(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym) psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899663|imex:IM-20960-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056637.1|refseq:XP_006519302.1|refseq:XP_006519303.1|refseq:XP_006519304.1|ensembl:ENSMUSG00000022124(gene)|ensembl:ENSMUST00000022720(transcript)|ensembl:ENSMUST00000145693(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168 refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H - - - figure legend:Supp. Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:X6zalZ4TQNZRr3LdC2Rw9hKRIW810090 rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090 intact-crc:BC3A0D0A09559F6D|rigid:1exX39X7Q/ZtvGVWa75bVuf00xw false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BFZ4 uniprotkb:O54943 intact:EBI-6898235|ensembl:ENSMUSP00000035248|uniprotkb:B2RSN8|uniprotkb:Q8BIJ8|uniprotkb:Q8BIW5 intact:EBI-1266779|uniprotkb:O54954 psi-mi:fxl21_mouse(display_long)|uniprotkb:Fbxl21(gene name)|psi-mi:Fbxl21(display_short)|uniprotkb:Fbl21(gene name synonym)|uniprotkb:Fbxl3b(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 21(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3B(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3B(gene name synonym) psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899655|imex:IM-20960-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333661.1|ensembl:ENSMUSG00000035509(gene)|ensembl:ENSMUST00000045428(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_848789.2 refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H - - - figure legend:Supp. Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:Jpfnj3lalb7I39q60IfhdDnLIfA10090 rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090 intact-crc:30E212D6C7DD1640|rigid:ONwmEfpp+rIa5PB7AwKpLjk4R0Y false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BFZ4 uniprotkb:P97784 intact:EBI-6898235|ensembl:ENSMUSP00000035248|uniprotkb:B2RSN8|uniprotkb:Q8BIJ8|uniprotkb:Q8BIW5 intact:EBI-1266607|ensembl:ENSMUSP00000020227 psi-mi:fxl21_mouse(display_long)|uniprotkb:Fbxl21(gene name)|psi-mi:Fbxl21(display_short)|uniprotkb:Fbl21(gene name synonym)|uniprotkb:Fbxl3b(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 21(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3B(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3B(gene name synonym) psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899400|imex:IM-20960-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333661.1|ensembl:ENSMUSG00000035509(gene)|ensembl:ENSMUST00000045428(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_848789.2 refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm) - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:Jpfnj3lalb7I39q60IfhdDnLIfA10090 rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090 intact-crc:656F0460D1727D8C|rigid:4KoAFJD9mwy7qwLIoz5z6iZ0kjo false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BFZ4 uniprotkb:P97784 intact:EBI-6898235|ensembl:ENSMUSP00000035248|uniprotkb:B2RSN8|uniprotkb:Q8BIJ8|uniprotkb:Q8BIW5 intact:EBI-1266607|ensembl:ENSMUSP00000020227 psi-mi:fxl21_mouse(display_long)|uniprotkb:Fbxl21(gene name)|psi-mi:Fbxl21(display_short)|uniprotkb:Fbl21(gene name synonym)|uniprotkb:Fbxl3b(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 21(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3B(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3B(gene name synonym) psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899576|imex:IM-20960-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333661.1|ensembl:ENSMUSG00000035509(gene)|ensembl:ENSMUST00000045428(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_848789.2 refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm) - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:Jpfnj3lalb7I39q60IfhdDnLIfA10090 rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090 intact-crc:DCC402F8CFBCDFAA|rigid:4Rqs52bknUFy1OzUQVo4x3n95wM false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BFZ4 uniprotkb:Q13616 intact:EBI-6898235|ensembl:ENSMUSP00000035248|uniprotkb:B2RSN8|uniprotkb:Q8BIJ8|uniprotkb:Q8BIW5 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:fxl21_mouse(display_long)|uniprotkb:Fbxl21(gene name)|psi-mi:Fbxl21(display_short)|uniprotkb:Fbl21(gene name synonym)|uniprotkb:Fbxl3b(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 21(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3B(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3B(gene name synonym) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899576|imex:IM-20960-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333661.1|ensembl:ENSMUSG00000035509(gene)|ensembl:ENSMUST00000045428(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_848789.2 refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:Jpfnj3lalb7I39q60IfhdDnLIfA10090 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 intact-crc:DCC402F8CFBCDFAA|rigid:4Rqs52bknUFy1OzUQVo4x3n95wM false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BFZ4 uniprotkb:P63208 intact:EBI-6898235|ensembl:ENSMUSP00000035248|uniprotkb:B2RSN8|uniprotkb:Q8BIJ8|uniprotkb:Q8BIW5 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:fxl21_mouse(display_long)|uniprotkb:Fbxl21(gene name)|psi-mi:Fbxl21(display_short)|uniprotkb:Fbl21(gene name synonym)|uniprotkb:Fbxl3b(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 21(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3B(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3B(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899576|imex:IM-20960-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333661.1|ensembl:ENSMUSG00000035509(gene)|ensembl:ENSMUST00000045428(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_848789.2 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:Jpfnj3lalb7I39q60IfhdDnLIfA10090 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:DCC402F8CFBCDFAA|rigid:4Rqs52bknUFy1OzUQVo4x3n95wM false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BFZ4 uniprotkb:Q13616 intact:EBI-6898235|ensembl:ENSMUSP00000035248|uniprotkb:B2RSN8|uniprotkb:Q8BIJ8|uniprotkb:Q8BIW5 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:fxl21_mouse(display_long)|uniprotkb:Fbxl21(gene name)|psi-mi:Fbxl21(display_short)|uniprotkb:Fbl21(gene name synonym)|uniprotkb:Fbxl3b(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 21(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3B(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3B(gene name synonym) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899607|imex:IM-20960-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333661.1|ensembl:ENSMUSG00000035509(gene)|ensembl:ENSMUST00000045428(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_848789.2 refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:Jpfnj3lalb7I39q60IfhdDnLIfA10090 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 intact-crc:87E4EC25F8A9A6C5|rigid:Ubmg6iQpqucm9xbzn1PtmLolofM false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BFZ4 uniprotkb:P63208 intact:EBI-6898235|ensembl:ENSMUSP00000035248|uniprotkb:B2RSN8|uniprotkb:Q8BIJ8|uniprotkb:Q8BIW5 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:fxl21_mouse(display_long)|uniprotkb:Fbxl21(gene name)|psi-mi:Fbxl21(display_short)|uniprotkb:Fbl21(gene name synonym)|uniprotkb:Fbxl3b(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 21(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3B(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3B(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899607|imex:IM-20960-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333661.1|ensembl:ENSMUSG00000035509(gene)|ensembl:ENSMUST00000045428(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_848789.2 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:Jpfnj3lalb7I39q60IfhdDnLIfA10090 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:87E4EC25F8A9A6C5|rigid:Ubmg6iQpqucm9xbzn1PtmLolofM false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BFZ4 uniprotkb:Q9R194 intact:EBI-6898235|ensembl:ENSMUSP00000035248|uniprotkb:B2RSN8|uniprotkb:Q8BIJ8|uniprotkb:Q8BIW5 intact:EBI-1266619|uniprotkb:O08706|uniprotkb:Q6A024|ensembl:ENSMUSP00000088047|ensembl:ENSMUSP00000106909 psi-mi:fxl21_mouse(display_long)|uniprotkb:Fbxl21(gene name)|psi-mi:Fbxl21(display_short)|uniprotkb:Fbl21(gene name synonym)|uniprotkb:Fbxl3b(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 21(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3B(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3B(gene name synonym) psi-mi:cry2_mouse(display_long)|uniprotkb:Cry2(gene name)|psi-mi:Cry2(display_short)|uniprotkb:Kiaa0658(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899607|imex:IM-20960-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333661.1|ensembl:ENSMUSG00000035509(gene)|ensembl:ENSMUST00000045428(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_848789.2 refseq:NP_034093.1|refseq:XP_017170770.1|dip:DIP-38517N|ensembl:ENSMUSG00000068742(gene)|ensembl:ENSMUST00000090559(transcript)|ensembl:ENSMUST00000111278(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071949"(FAD binding)|go:"GO:2000118"(regulation of sodium-dependent phosphate transport)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:Q9R194|rcsb pdb:4I6E|rcsb pdb:4I6G|rcsb pdb:4I6J|rcsb pdb:4MLP|rcsb pdb:4U8H|rcsb pdb:6KX8|rcsb pdb:7D0N|rcsb pdb:7EJ9 - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:Jpfnj3lalb7I39q60IfhdDnLIfA10090 rogid:00SKIwCL33BKjjyPSsxZUR5Sjbs10090 intact-crc:87E4EC25F8A9A6C5|rigid:Ubmg6iQpqucm9xbzn1PtmLolofM false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8C4V4 uniprotkb:P63208 intact:EBI-1266589|uniprotkb:Q80V32|uniprotkb:Q8K1W0|uniprotkb:Q9QXW1|ensembl:ENSMUSP00000022720|ensembl:ENSMUSP00000116044 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:fbxl3_mouse(display_long)|uniprotkb:Afh(gene name synonym)|uniprotkb:Ovtm(gene name synonym)|uniprotkb:Protein after-hours(gene name synonym)|uniprotkb:Protein overtime(gene name synonym)|uniprotkb:Fbxl3(gene name)|psi-mi:Fbxl3(display_short)|uniprotkb:Fbl3a(gene name synonym)|uniprotkb:Fbxl3a(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899510|imex:IM-20960-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056637.1|refseq:XP_006519302.1|refseq:XP_006519303.1|refseq:XP_006519304.1|ensembl:ENSMUSG00000022124(gene)|ensembl:ENSMUST00000022720(transcript)|ensembl:ENSMUST00000145693(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:X6zalZ4TQNZRr3LdC2Rw9hKRIW810090 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:8462A3807E30D6C5|rigid:1lBFc4CxLaqR7SqdNi1FZdRiItk false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8C4V4 uniprotkb:Q9R194 intact:EBI-1266589|uniprotkb:Q80V32|uniprotkb:Q8K1W0|uniprotkb:Q9QXW1|ensembl:ENSMUSP00000022720|ensembl:ENSMUSP00000116044 intact:EBI-1266619|uniprotkb:O08706|uniprotkb:Q6A024|ensembl:ENSMUSP00000088047|ensembl:ENSMUSP00000106909 psi-mi:fbxl3_mouse(display_long)|uniprotkb:Afh(gene name synonym)|uniprotkb:Ovtm(gene name synonym)|uniprotkb:Protein after-hours(gene name synonym)|uniprotkb:Protein overtime(gene name synonym)|uniprotkb:Fbxl3(gene name)|psi-mi:Fbxl3(display_short)|uniprotkb:Fbl3a(gene name synonym)|uniprotkb:Fbxl3a(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym) psi-mi:cry2_mouse(display_long)|uniprotkb:Cry2(gene name)|psi-mi:Cry2(display_short)|uniprotkb:Kiaa0658(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899510|imex:IM-20960-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056637.1|refseq:XP_006519302.1|refseq:XP_006519303.1|refseq:XP_006519304.1|ensembl:ENSMUSG00000022124(gene)|ensembl:ENSMUST00000022720(transcript)|ensembl:ENSMUST00000145693(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168 refseq:NP_034093.1|refseq:XP_017170770.1|dip:DIP-38517N|ensembl:ENSMUSG00000068742(gene)|ensembl:ENSMUST00000090559(transcript)|ensembl:ENSMUST00000111278(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071949"(FAD binding)|go:"GO:2000118"(regulation of sodium-dependent phosphate transport)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:Q9R194|rcsb pdb:4I6E|rcsb pdb:4I6G|rcsb pdb:4I6J|rcsb pdb:4MLP|rcsb pdb:4U8H|rcsb pdb:6KX8|rcsb pdb:7D0N|rcsb pdb:7EJ9 - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:X6zalZ4TQNZRr3LdC2Rw9hKRIW810090 rogid:00SKIwCL33BKjjyPSsxZUR5Sjbs10090 intact-crc:8462A3807E30D6C5|rigid:1lBFc4CxLaqR7SqdNi1FZdRiItk false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8C4V4 uniprotkb:Q13616 intact:EBI-1266589|uniprotkb:Q80V32|uniprotkb:Q8K1W0|uniprotkb:Q9QXW1|ensembl:ENSMUSP00000022720|ensembl:ENSMUSP00000116044 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:fbxl3_mouse(display_long)|uniprotkb:Afh(gene name synonym)|uniprotkb:Ovtm(gene name synonym)|uniprotkb:Protein after-hours(gene name synonym)|uniprotkb:Protein overtime(gene name synonym)|uniprotkb:Fbxl3(gene name)|psi-mi:Fbxl3(display_short)|uniprotkb:Fbl3a(gene name synonym)|uniprotkb:Fbxl3a(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899510|imex:IM-20960-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056637.1|refseq:XP_006519302.1|refseq:XP_006519303.1|refseq:XP_006519304.1|ensembl:ENSMUSG00000022124(gene)|ensembl:ENSMUST00000022720(transcript)|ensembl:ENSMUST00000145693(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168 refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:X6zalZ4TQNZRr3LdC2Rw9hKRIW810090 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 intact-crc:8462A3807E30D6C5|rigid:1lBFc4CxLaqR7SqdNi1FZdRiItk false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8C4V4 uniprotkb:P63208 intact:EBI-1266589|uniprotkb:Q80V32|uniprotkb:Q8K1W0|uniprotkb:Q9QXW1|ensembl:ENSMUSP00000022720|ensembl:ENSMUSP00000116044 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:fbxl3_mouse(display_long)|uniprotkb:Afh(gene name synonym)|uniprotkb:Ovtm(gene name synonym)|uniprotkb:Protein after-hours(gene name synonym)|uniprotkb:Protein overtime(gene name synonym)|uniprotkb:Fbxl3(gene name)|psi-mi:Fbxl3(display_short)|uniprotkb:Fbl3a(gene name synonym)|uniprotkb:Fbxl3a(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899391|imex:IM-20960-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056637.1|refseq:XP_006519302.1|refseq:XP_006519303.1|refseq:XP_006519304.1|ensembl:ENSMUSG00000022124(gene)|ensembl:ENSMUST00000022720(transcript)|ensembl:ENSMUST00000145693(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:X6zalZ4TQNZRr3LdC2Rw9hKRIW810090 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:DF8FAC22F4120593|rigid:FoMC5cFeA1XYVfGfoNBO6GzrAw8 false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8C4V4 uniprotkb:Q13616 intact:EBI-1266589|uniprotkb:Q80V32|uniprotkb:Q8K1W0|uniprotkb:Q9QXW1|ensembl:ENSMUSP00000022720|ensembl:ENSMUSP00000116044 intact:EBI-359390|uniprotkb:O60719|uniprotkb:Q08AL6|uniprotkb:Q8IYW1|uniprotkb:D3DWG3|ensembl:ENSP00000326804|ensembl:ENSP00000387160|ensembl:ENSP00000473318|ensembl:ENSP00000499255|ensembl:ENSP00000499277|ensembl:ENSP00000499398 psi-mi:fbxl3_mouse(display_long)|uniprotkb:Afh(gene name synonym)|uniprotkb:Ovtm(gene name synonym)|uniprotkb:Protein after-hours(gene name synonym)|uniprotkb:Protein overtime(gene name synonym)|uniprotkb:Fbxl3(gene name)|psi-mi:Fbxl3(display_short)|uniprotkb:Fbl3a(gene name synonym)|uniprotkb:Fbxl3a(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym) psi-mi:cul1_human(display_long)|uniprotkb:CUL1(gene name)|psi-mi:CUL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899391|imex:IM-20960-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056637.1|refseq:XP_006519302.1|refseq:XP_006519303.1|refseq:XP_006519304.1|ensembl:ENSMUSG00000022124(gene)|ensembl:ENSMUST00000022720(transcript)|ensembl:ENSMUST00000145693(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168 refseq:NP_003583.2|rcsb pdb:6WCQ|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5R|rcsb pdb:7B5S|reactome:R-HSA-1169091|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|refseq:XP_011514931.1|refseq:XP_011514932.1|refseq:XP_011514933.1|refseq:XP_011514934.1|ensembl:ENSG00000055130(gene)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|ensembl:ENST00000325222(transcript)|ensembl:ENST00000409469(transcript)|ensembl:ENST00000602748(transcript)|ensembl:ENST00000662716(transcript)|ensembl:ENST00000663044(transcript)|ensembl:ENST00000665936(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1990452"(Parkin-FBXW7-Cul1 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13616|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:3RTR|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5V89|rcsb pdb:6TTU|refseq:XP_005250117.1|dip:DIP-17013N - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:X6zalZ4TQNZRr3LdC2Rw9hKRIW810090 rogid:OAZP+ifWW3eEnQKb937ww9s1fMQ9606 intact-crc:DF8FAC22F4120593|rigid:FoMC5cFeA1XYVfGfoNBO6GzrAw8 false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8C4V4 uniprotkb:P97784 intact:EBI-1266589|uniprotkb:Q80V32|uniprotkb:Q8K1W0|uniprotkb:Q9QXW1|ensembl:ENSMUSP00000022720|ensembl:ENSMUSP00000116044 intact:EBI-1266607|ensembl:ENSMUSP00000020227 psi-mi:fbxl3_mouse(display_long)|uniprotkb:Afh(gene name synonym)|uniprotkb:Ovtm(gene name synonym)|uniprotkb:Protein after-hours(gene name synonym)|uniprotkb:Protein overtime(gene name synonym)|uniprotkb:Fbxl3(gene name)|psi-mi:Fbxl3(display_short)|uniprotkb:Fbl3a(gene name synonym)|uniprotkb:Fbxl3a(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym) psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6899391|imex:IM-20960-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056637.1|refseq:XP_006519302.1|refseq:XP_006519303.1|refseq:XP_006519304.1|ensembl:ENSMUSG00000022124(gene)|ensembl:ENSMUST00000022720(transcript)|ensembl:ENSMUST00000145693(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168 refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm) - - - figure legend:Fig. 4B, 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/07/23 2014/10/16 rogid:X6zalZ4TQNZRr3LdC2Rw9hKRIW810090 rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090 intact-crc:DF8FAC22F4120593|rigid:FoMC5cFeA1XYVfGfoNBO6GzrAw8 false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BFZ4 uniprotkb:P97784 intact:EBI-6898235|ensembl:ENSMUSP00000035248|uniprotkb:B2RSN8|uniprotkb:Q8BIJ8|uniprotkb:Q8BIW5 intact:EBI-1266607|ensembl:ENSMUSP00000020227 psi-mi:fxl21_mouse(display_long)|uniprotkb:Fbxl21(gene name)|psi-mi:Fbxl21(display_short)|uniprotkb:Fbl21(gene name synonym)|uniprotkb:Fbxl3b(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 21(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3B(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3B(gene name synonym) psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9526247|imex:IM-20960-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333661.1|ensembl:ENSMUSG00000035509(gene)|ensembl:ENSMUST00000045428(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_848789.2 refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm) - - - figure legend:Supp Fig.2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2013/07/23 2014/10/16 rogid:Jpfnj3lalb7I39q60IfhdDnLIfA10090 rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090 intact-crc:12BA7AC30A479CF0|rigid:4KoAFJD9mwy7qwLIoz5z6iZ0kjo false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8C4V4 uniprotkb:P97784 intact:EBI-1266589|uniprotkb:Q80V32|uniprotkb:Q8K1W0|uniprotkb:Q9QXW1|ensembl:ENSMUSP00000022720|ensembl:ENSMUSP00000116044 intact:EBI-1266607|ensembl:ENSMUSP00000020227 psi-mi:fbxl3_mouse(display_long)|uniprotkb:Afh(gene name synonym)|uniprotkb:Ovtm(gene name synonym)|uniprotkb:Protein after-hours(gene name synonym)|uniprotkb:Protein overtime(gene name synonym)|uniprotkb:Fbxl3(gene name)|psi-mi:Fbxl3(display_short)|uniprotkb:Fbl3a(gene name synonym)|uniprotkb:Fbxl3a(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym) psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9526227|imex:IM-20960-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056637.1|refseq:XP_006519302.1|refseq:XP_006519303.1|refseq:XP_006519304.1|ensembl:ENSMUSG00000022124(gene)|ensembl:ENSMUST00000022720(transcript)|ensembl:ENSMUST00000145693(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168 refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm) - - - figure legend:Supp. Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2013/07/23 2014/10/16 rogid:X6zalZ4TQNZRr3LdC2Rw9hKRIW810090 rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090 intact-crc:A13AEB36659F2BB8|rigid:pbEx5mzbsrMQpWrr/MkQ7q+oukU false flag tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P97784 uniprotkb:Q8BFZ4 intact:EBI-1266607|ensembl:ENSMUSP00000020227 intact:EBI-6898235|ensembl:ENSMUSP00000035248|uniprotkb:B2RSN8|uniprotkb:Q8BIJ8|uniprotkb:Q8BIW5 psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short) psi-mi:fxl21_mouse(display_long)|uniprotkb:Fbxl21(gene name)|psi-mi:Fbxl21(display_short)|uniprotkb:Fbl21(gene name synonym)|uniprotkb:Fbxl3b(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 21(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3B(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9526255|imex:IM-20960-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm) refseq:NP_001333661.1|ensembl:ENSMUSG00000035509(gene)|ensembl:ENSMUST00000045428(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_848789.2 - - - figure legend:Supp Fig.2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2013/07/23 2014/10/16 rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090 rogid:Jpfnj3lalb7I39q60IfhdDnLIfA10090 intact-crc:65290BEFF4866E5F|rigid:qCzPjcJjeBwpYgyb/kpFayoWdmI false myc tag:?-? flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P97784 uniprotkb:Q8C4V4 intact:EBI-1266607|ensembl:ENSMUSP00000020227 intact:EBI-1266589|uniprotkb:Q80V32|uniprotkb:Q8K1W0|uniprotkb:Q9QXW1|ensembl:ENSMUSP00000022720|ensembl:ENSMUSP00000116044 psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short) psi-mi:fbxl3_mouse(display_long)|uniprotkb:Afh(gene name synonym)|uniprotkb:Ovtm(gene name synonym)|uniprotkb:Protein after-hours(gene name synonym)|uniprotkb:Protein overtime(gene name synonym)|uniprotkb:Fbxl3(gene name)|psi-mi:Fbxl3(display_short)|uniprotkb:Fbl3a(gene name synonym)|uniprotkb:Fbxl3a(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 3A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hirano et al. (2013) imex:IM-20960|pubmed:23452856 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9526255|imex:IM-20960-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm) refseq:NP_056637.1|refseq:XP_006519302.1|refseq:XP_006519303.1|refseq:XP_006519304.1|ensembl:ENSMUSG00000022124(gene)|ensembl:ENSMUST00000022720(transcript)|ensembl:ENSMUST00000145693(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|reactome:R-MMU-8951664|reactome:R-MMU-983168 - - - figure legend:Supp Fig.2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2013/07/23 2014/10/16 rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090 rogid:X6zalZ4TQNZRr3LdC2Rw9hKRIW810090 intact-crc:65290BEFF4866E5F|rigid:qCzPjcJjeBwpYgyb/kpFayoWdmI false myc tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)