#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32597 uniprotkb:P38181 intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W intact:EBI-11756|ensemblfungi:YBL079W|uniprotkb:D6VPS4 psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:nu170_yeast(display_long)|uniprotkb:NUP170(gene name)|psi-mi:NUP170(display_short)|uniprotkb:NLE3(gene name synonym)|uniprotkb:YBL079W(locus name)|uniprotkb:YBL0725(orf name)|uniprotkb:Nuclear pore protein NUP170(gene name synonym) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879758|imex:IM-20939-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 ensemblfungi:YBL079W(gene)|ensemblfungi:YBL079W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006342"|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:3I5P|rcsb pdb:3I5Q|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|refseq:NP_009474.1|sgd:S000000175|mint:P38181|dip:DIP-2450N - crc64:269A91BD853C20D0 crc64:3BEA65DAA2A5F99A figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 rogid:6CjNCgT5bb3uX7koAOPjJcaoW/Q559292 intact-crc:DD4A4FF369170D3D|rigid:hmFXFRd3i22UF0+XB4u3CrOHX2w false protein a tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32597 uniprotkb:Q06639 intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W intact:EBI-22058|uniprotkb:D6VST2|ensemblfungi:YDR303C psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:rsc3_yeast(display_long)|uniprotkb:Remodel the structure of chromatin complex subunit 3(gene name synonym)|uniprotkb:RSC3(gene name)|psi-mi:RSC3(display_short)|uniprotkb:YDR303C(locus name)|uniprotkb:D9740.13(orf name) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879758|imex:IM-20939-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 sgd:S000002711|refseq:NP_010589.3|dip:DIP-5867N|ensemblfungi:YDR303C(gene)|ensemblfungi:YDR303C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0043044"|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0043565"(sequence-specific DNA binding)|mint:Q06639 - crc64:269A91BD853C20D0 - figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 rogid:Mn5cFKxVYEpAAQz7QSnxOVtr4lQ559292 intact-crc:DD4A4FF369170D3D|rigid:hmFXFRd3i22UF0+XB4u3CrOHX2w false protein a tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32597 uniprotkb:Q03790 intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W intact:EBI-27321|uniprotkb:D6VZX4|ensemblfungi:YMR153W psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:nup53_yeast(display_long)|uniprotkb:Nuclear pore protein NUP53(gene name synonym)|uniprotkb:NUP53(gene name)|psi-mi:NUP53(display_short)|uniprotkb:YMR153W(locus name)|uniprotkb:YM8520.02(orf name) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879758|imex:IM-20939-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 refseq:NP_013873.1|sgd:S000004762|dip:DIP-1467N|ensemblfungi:YMR153W(gene)|ensemblfungi:YMR153W_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0072417"(response to spindle checkpoint signaling)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|rcsb pdb:3W3Y|rcsb pdb:5UAZ - crc64:269A91BD853C20D0 crc64:2ECE0C561D27E523 figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 rogid:csq2oRFswkgY2JkT+dmz/L7Zpfk559292 intact-crc:DD4A4FF369170D3D|rigid:hmFXFRd3i22UF0+XB4u3CrOHX2w false protein a tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32597 uniprotkb:P38781 intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W intact:EBI-24549|uniprotkb:D3DL05|ensemblfungi:YHR056C psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:rsc30_yeast(display_long)|uniprotkb:RSC30(gene name)|psi-mi:RSC30(display_short)|uniprotkb:Remodel the structure of chromatin complex subunit 30(gene name synonym)|uniprotkb:YHR056C(locus name) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879758|imex:IM-20939-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 refseq:NP_011923.2|sgd:S000001098|dip:DIP-4275N|ensemblfungi:YHR056C(gene)|ensemblfungi:YHR056C_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006337"(nucleosome disassembly)|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6V8O|rcsb pdb:6V92|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016586"(RSC-type complex)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|rcsb pdb:6K15|rcsb pdb:6KW3 - crc64:269A91BD853C20D0 - figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 rogid:NzGOxIaNyDat2EcQdWPobugunh0559292 intact-crc:DD4A4FF369170D3D|rigid:hmFXFRd3i22UF0+XB4u3CrOHX2w false protein a tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03790 uniprotkb:P38181 intact:EBI-27321|uniprotkb:D6VZX4|ensemblfungi:YMR153W intact:EBI-11756|ensemblfungi:YBL079W|uniprotkb:D6VPS4 psi-mi:nup53_yeast(display_long)|uniprotkb:Nuclear pore protein NUP53(gene name synonym)|uniprotkb:NUP53(gene name)|psi-mi:NUP53(display_short)|uniprotkb:YMR153W(locus name)|uniprotkb:YM8520.02(orf name) psi-mi:nu170_yeast(display_long)|uniprotkb:NUP170(gene name)|psi-mi:NUP170(display_short)|uniprotkb:NLE3(gene name synonym)|uniprotkb:YBL079W(locus name)|uniprotkb:YBL0725(orf name)|uniprotkb:Nuclear pore protein NUP170(gene name synonym) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879778|imex:IM-20939-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013873.1|sgd:S000004762|dip:DIP-1467N|ensemblfungi:YMR153W(gene)|ensemblfungi:YMR153W_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0072417"(response to spindle checkpoint signaling)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|rcsb pdb:3W3Y|rcsb pdb:5UAZ ensemblfungi:YBL079W(gene)|ensemblfungi:YBL079W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006342"|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:3I5P|rcsb pdb:3I5Q|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|refseq:NP_009474.1|sgd:S000000175|mint:P38181|dip:DIP-2450N - crc64:2ECE0C561D27E523 crc64:3BEA65DAA2A5F99A figure legend:Fig. 6A, suppl. fig. 7D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:csq2oRFswkgY2JkT+dmz/L7Zpfk559292 rogid:6CjNCgT5bb3uX7koAOPjJcaoW/Q559292 intact-crc:2DAE7CA46BFA41CF|rigid:Am99G7iLNAmbIBo+YV4LydKtOjg false - protein a tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11938 uniprotkb:Q03790 intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W intact:EBI-27321|uniprotkb:D6VZX4|ensemblfungi:YMR153W psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym) psi-mi:nup53_yeast(display_long)|uniprotkb:Nuclear pore protein NUP53(gene name synonym)|uniprotkb:NUP53(gene name)|psi-mi:NUP53(display_short)|uniprotkb:YMR153W(locus name)|uniprotkb:YM8520.02(orf name) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879805|imex:IM-20939-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938 refseq:NP_013873.1|sgd:S000004762|dip:DIP-1467N|ensemblfungi:YMR153W(gene)|ensemblfungi:YMR153W_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0072417"(response to spindle checkpoint signaling)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|rcsb pdb:3W3Y|rcsb pdb:5UAZ - crc64:67C4AFB03B3C0713 crc64:2ECE0C561D27E523 figure legend:Fig. 6D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292 rogid:csq2oRFswkgY2JkT+dmz/L7Zpfk559292 intact-crc:427C975A0DBAC689|rigid:Fu5BvikBOrafuFoAf+9KMnIGHJw false protein a tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11938 uniprotkb:P38181 intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W intact:EBI-11756|ensemblfungi:YBL079W|uniprotkb:D6VPS4 psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym) psi-mi:nu170_yeast(display_long)|uniprotkb:NUP170(gene name)|psi-mi:NUP170(display_short)|uniprotkb:NLE3(gene name synonym)|uniprotkb:YBL079W(locus name)|uniprotkb:YBL0725(orf name)|uniprotkb:Nuclear pore protein NUP170(gene name synonym) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879805|imex:IM-20939-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938 ensemblfungi:YBL079W(gene)|ensemblfungi:YBL079W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006342"|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:3I5P|rcsb pdb:3I5Q|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|refseq:NP_009474.1|sgd:S000000175|mint:P38181|dip:DIP-2450N - crc64:67C4AFB03B3C0713 crc64:3BEA65DAA2A5F99A figure legend:Fig. 6D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292 rogid:6CjNCgT5bb3uX7koAOPjJcaoW/Q559292 intact-crc:427C975A0DBAC689|rigid:Fu5BvikBOrafuFoAf+9KMnIGHJw false protein a tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38181 uniprotkb:P11978 intact:EBI-11756|ensemblfungi:YBL079W|uniprotkb:D6VPS4 intact:EBI-17237|uniprotkb:D6VSK9|ensemblfungi:YDR227W psi-mi:nu170_yeast(display_long)|uniprotkb:NUP170(gene name)|psi-mi:NUP170(display_short)|uniprotkb:NLE3(gene name synonym)|uniprotkb:YBL079W(locus name)|uniprotkb:YBL0725(orf name)|uniprotkb:Nuclear pore protein NUP170(gene name synonym) psi-mi:sir4_yeast(display_long)|uniprotkb:STE9(gene name synonym)|uniprotkb:SIR4(gene name)|psi-mi:SIR4(display_short)|uniprotkb:ASD1(gene name synonym)|uniprotkb:UTH2(gene name synonym)|uniprotkb:YDR227W(locus name)|uniprotkb:YD9934.12(orf name)|uniprotkb:Silent information regulator 4(gene name synonym) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879786|imex:IM-20939-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL079W(gene)|ensemblfungi:YBL079W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006342"|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:3I5P|rcsb pdb:3I5Q|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|refseq:NP_009474.1|sgd:S000000175|mint:P38181|dip:DIP-2450N refseq:NP_010513.1|sgd:S000002635|ensemblfungi:YDR227W(gene)|ensemblfungi:YDR227W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR031556|rcsb pdb:1NYH|rcsb pdb:1PL5|rcsb pdb:4IAO|rcsb pdb:6QSZ|rcsb pdb:6QTM|rcsb pdb:6RR0|rcsb pdb:6RRV|dip:DIP-33N|mint:P11978 - crc64:3BEA65DAA2A5F99A crc64:9C698765964F094E figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:6CjNCgT5bb3uX7koAOPjJcaoW/Q559292 rogid:C1HZEbdzRxwODKN1FHzmhYMCl+M559292 intact-crc:31AB8B874EB1352D|rigid:baQK1sjmxZpE13Lt2565RzsnNS4 false protein a tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38181 uniprotkb:Q03790 intact:EBI-11756|ensemblfungi:YBL079W|uniprotkb:D6VPS4 intact:EBI-27321|uniprotkb:D6VZX4|ensemblfungi:YMR153W psi-mi:nu170_yeast(display_long)|uniprotkb:NUP170(gene name)|psi-mi:NUP170(display_short)|uniprotkb:NLE3(gene name synonym)|uniprotkb:YBL079W(locus name)|uniprotkb:YBL0725(orf name)|uniprotkb:Nuclear pore protein NUP170(gene name synonym) psi-mi:nup53_yeast(display_long)|uniprotkb:Nuclear pore protein NUP53(gene name synonym)|uniprotkb:NUP53(gene name)|psi-mi:NUP53(display_short)|uniprotkb:YMR153W(locus name)|uniprotkb:YM8520.02(orf name) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879786|imex:IM-20939-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL079W(gene)|ensemblfungi:YBL079W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006342"|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:3I5P|rcsb pdb:3I5Q|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|refseq:NP_009474.1|sgd:S000000175|mint:P38181|dip:DIP-2450N refseq:NP_013873.1|sgd:S000004762|dip:DIP-1467N|ensemblfungi:YMR153W(gene)|ensemblfungi:YMR153W_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0072417"(response to spindle checkpoint signaling)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|rcsb pdb:3W3Y|rcsb pdb:5UAZ - crc64:3BEA65DAA2A5F99A crc64:2ECE0C561D27E523 figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:6CjNCgT5bb3uX7koAOPjJcaoW/Q559292 rogid:csq2oRFswkgY2JkT+dmz/L7Zpfk559292 intact-crc:31AB8B874EB1352D|rigid:baQK1sjmxZpE13Lt2565RzsnNS4 false protein a tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11938 uniprotkb:P38181 intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W intact:EBI-11756|ensemblfungi:YBL079W|uniprotkb:D6VPS4 psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym) psi-mi:nu170_yeast(display_long)|uniprotkb:NUP170(gene name)|psi-mi:NUP170(display_short)|uniprotkb:NLE3(gene name synonym)|uniprotkb:YBL079W(locus name)|uniprotkb:YBL0725(orf name)|uniprotkb:Nuclear pore protein NUP170(gene name synonym) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879823|imex:IM-20939-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938 ensemblfungi:YBL079W(gene)|ensemblfungi:YBL079W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006342"|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:3I5P|rcsb pdb:3I5Q|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|refseq:NP_009474.1|sgd:S000000175|mint:P38181|dip:DIP-2450N - crc64:67C4AFB03B3C0713 crc64:3BEA65DAA2A5F99A figure legend:Fig. 7A|comment:Interaction greatly reduced in NUP170-/- cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292 rogid:6CjNCgT5bb3uX7koAOPjJcaoW/Q559292 intact-crc:FC16F5E33A012661|rigid:jabomyNmDCFMblAtjBgHPm9kQlU false protein a tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11938 uniprotkb:P11978 intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W intact:EBI-17237|uniprotkb:D6VSK9|ensemblfungi:YDR227W psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym) psi-mi:sir4_yeast(display_long)|uniprotkb:STE9(gene name synonym)|uniprotkb:SIR4(gene name)|psi-mi:SIR4(display_short)|uniprotkb:ASD1(gene name synonym)|uniprotkb:UTH2(gene name synonym)|uniprotkb:YDR227W(locus name)|uniprotkb:YD9934.12(orf name)|uniprotkb:Silent information regulator 4(gene name synonym) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879823|imex:IM-20939-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938 refseq:NP_010513.1|sgd:S000002635|ensemblfungi:YDR227W(gene)|ensemblfungi:YDR227W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR031556|rcsb pdb:1NYH|rcsb pdb:1PL5|rcsb pdb:4IAO|rcsb pdb:6QSZ|rcsb pdb:6QTM|rcsb pdb:6RR0|rcsb pdb:6RRV|dip:DIP-33N|mint:P11978 - crc64:67C4AFB03B3C0713 crc64:9C698765964F094E figure legend:Fig. 7A|comment:Interaction greatly reduced in NUP170-/- cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292 rogid:C1HZEbdzRxwODKN1FHzmhYMCl+M559292 intact-crc:FC16F5E33A012661|rigid:jabomyNmDCFMblAtjBgHPm9kQlU false protein a tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11938 uniprotkb:P38181 intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W intact:EBI-11756|ensemblfungi:YBL079W|uniprotkb:D6VPS4 psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym) psi-mi:nu170_yeast(display_long)|uniprotkb:NUP170(gene name)|psi-mi:NUP170(display_short)|uniprotkb:NLE3(gene name synonym)|uniprotkb:YBL079W(locus name)|uniprotkb:YBL0725(orf name)|uniprotkb:Nuclear pore protein NUP170(gene name synonym) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8785971|imex:IM-20939-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938 ensemblfungi:YBL079W(gene)|ensemblfungi:YBL079W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006342"|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:3I5P|rcsb pdb:3I5Q|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|refseq:NP_009474.1|sgd:S000000175|mint:P38181|dip:DIP-2450N - crc64:67C4AFB03B3C0713 crc64:3BEA65DAA2A5F99A figure legend:Fig. 7A|comment:Interaction greatly reduced in NUP170-/- cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292 rogid:6CjNCgT5bb3uX7koAOPjJcaoW/Q559292 intact-crc:1413B41B7BC0A7C4|rigid:QWeCQjqpUdbIh82+fSkva/bmUGY false protein a tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11938 uniprotkb:Q03790 intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W intact:EBI-27321|uniprotkb:D6VZX4|ensemblfungi:YMR153W psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym) psi-mi:nup53_yeast(display_long)|uniprotkb:Nuclear pore protein NUP53(gene name synonym)|uniprotkb:NUP53(gene name)|psi-mi:NUP53(display_short)|uniprotkb:YMR153W(locus name)|uniprotkb:YM8520.02(orf name) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8785971|imex:IM-20939-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938 refseq:NP_013873.1|sgd:S000004762|dip:DIP-1467N|ensemblfungi:YMR153W(gene)|ensemblfungi:YMR153W_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0072417"(response to spindle checkpoint signaling)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|rcsb pdb:3W3Y|rcsb pdb:5UAZ - crc64:67C4AFB03B3C0713 crc64:2ECE0C561D27E523 figure legend:Fig. 7A|comment:Interaction greatly reduced in NUP170-/- cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292 rogid:csq2oRFswkgY2JkT+dmz/L7Zpfk559292 intact-crc:1413B41B7BC0A7C4|rigid:QWeCQjqpUdbIh82+fSkva/bmUGY false protein a tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11938 uniprotkb:P11978 intact:EBI-14821|uniprotkb:D6W0X4|ensemblfungi:YNL216W intact:EBI-17237|uniprotkb:D6VSK9|ensemblfungi:YDR227W psi-mi:rap1_yeast(display_long)|uniprotkb:RAP1(gene name)|psi-mi:RAP1(display_short)|uniprotkb:GRF1(gene name synonym)|uniprotkb:TUF1(gene name synonym)|uniprotkb:YNL216W(locus name)|uniprotkb:N1310(orf name)|uniprotkb:SBF-E(gene name synonym)|uniprotkb:Repressor/activator site-binding protein(gene name synonym)|uniprotkb:TUF(gene name synonym) psi-mi:sir4_yeast(display_long)|uniprotkb:STE9(gene name synonym)|uniprotkb:SIR4(gene name)|psi-mi:SIR4(display_short)|uniprotkb:ASD1(gene name synonym)|uniprotkb:UTH2(gene name synonym)|uniprotkb:YDR227W(locus name)|uniprotkb:YD9934.12(orf name)|uniprotkb:Silent information regulator 4(gene name synonym) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-8785971|imex:IM-20939-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005160|refseq:NP_014183.1|ensemblfungi:YNL216W(gene)|ensemblfungi:YNL216W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001207"(obsolete histone displacement)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015280(Rap1, DNA-binding)|interpro:IPR017930|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|rcsb pdb:1IGN|rcsb pdb:2L42|rcsb pdb:3CZ6|rcsb pdb:3OWT|rcsb pdb:3UKG|rcsb pdb:4BJ5|rcsb pdb:4BJ6|rcsb pdb:4BJT|rcsb pdb:4GFB|rcsb pdb:6LDM|dip:DIP-851N|mint:P11938 refseq:NP_010513.1|sgd:S000002635|ensemblfungi:YDR227W(gene)|ensemblfungi:YDR227W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR031556|rcsb pdb:1NYH|rcsb pdb:1PL5|rcsb pdb:4IAO|rcsb pdb:6QSZ|rcsb pdb:6QTM|rcsb pdb:6RR0|rcsb pdb:6RRV|dip:DIP-33N|mint:P11978 - crc64:67C4AFB03B3C0713 crc64:9C698765964F094E figure legend:Fig. 7A|comment:Interaction greatly reduced in NUP170-/- cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:YlfPuIgolQHJhtYoX6icgCpvagQ559292 rogid:C1HZEbdzRxwODKN1FHzmhYMCl+M559292 intact-crc:1413B41B7BC0A7C4|rigid:QWeCQjqpUdbIh82+fSkva/bmUGY false protein a tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P38181 uniprotkb:P32597 intact:EBI-11756|ensemblfungi:YBL079W|uniprotkb:D6VPS4 intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W psi-mi:nu170_yeast(display_long)|uniprotkb:NUP170(gene name)|psi-mi:NUP170(display_short)|uniprotkb:NLE3(gene name synonym)|uniprotkb:YBL079W(locus name)|uniprotkb:YBL0725(orf name)|uniprotkb:Nuclear pore protein NUP170(gene name synonym) psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879769|imex:IM-20939-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL079W(gene)|ensemblfungi:YBL079W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006342"|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:3I5P|rcsb pdb:3I5Q|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|refseq:NP_009474.1|sgd:S000000175|mint:P38181|dip:DIP-2450N refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 - crc64:3BEA65DAA2A5F99A crc64:269A91BD853C20D0 figure legend:Fig. 2H|comment:Interaction occurs in NUP53-/- cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:6CjNCgT5bb3uX7koAOPjJcaoW/Q559292 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 intact-crc:6D8BD2DED3B11BF8|rigid:gva5UuPIc0bvEqunrXAMaL54rYU false myc tag:?-? protein a tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38181 uniprotkb:P32597 intact:EBI-11756|ensemblfungi:YBL079W|uniprotkb:D6VPS4 intact:EBI-18410|uniprotkb:Q45U09|uniprotkb:D6VVG1|ensemblfungi:YIL126W psi-mi:nu170_yeast(display_long)|uniprotkb:NUP170(gene name)|psi-mi:NUP170(display_short)|uniprotkb:NLE3(gene name synonym)|uniprotkb:YBL079W(locus name)|uniprotkb:YBL0725(orf name)|uniprotkb:Nuclear pore protein NUP170(gene name synonym) psi-mi:sth1_yeast(display_long)|uniprotkb:STH1(gene name)|psi-mi:STH1(display_short)|uniprotkb:NPS1(gene name synonym)|uniprotkb:ATP-dependent helicase STH1(gene name synonym)|uniprotkb:Chromatin structure-remodeling complex protein STH1(gene name synonym)|uniprotkb:SNF2 homolog(gene name synonym)|uniprotkb:YIL126W(locus name) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879743|imex:IM-20939-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL079W(gene)|ensemblfungi:YBL079W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006342"|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:3I5P|rcsb pdb:3I5Q|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|refseq:NP_009474.1|sgd:S000000175|mint:P38181|dip:DIP-2450N refseq:NP_012140.1|sgd:S000001388|ensemblfungi:YIL126W(gene)|ensemblfungi:YIL126W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016586"(RSC-type complex)|go:"GO:0031055"(chromatin remodeling at centromere)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR036427|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007010"(cytoskeleton organization)|interpro:IPR038718|rcsb pdb:6K15|rcsb pdb:6KMB|rcsb pdb:6KMJ|rcsb pdb:6KW3|rcsb pdb:6KW4|rcsb pdb:6KW5|rcsb pdb:6LQZ|rcsb pdb:6MR4|rcsb pdb:6TDA|rcsb pdb:6UY1|rcsb pdb:6V8O|rcsb pdb:6V92|rcsb pdb:6VZ4|rcsb pdb:6VZG|reactome:R-SCE-3214858|dip:DIP-5889N|mint:P32597 - crc64:3BEA65DAA2A5F99A crc64:269A91BD853C20D0 figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:6CjNCgT5bb3uX7koAOPjJcaoW/Q559292 rogid:uNQ0+Tk78keY/nPc3+9Hk3GVxmo559292 intact-crc:634B89A7B6CFCCA8|rigid:gva5UuPIc0bvEqunrXAMaL54rYU false protein a tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P40064 uniprotkb:P11978 intact:EBI-11740|ensemblfungi:YER105C|uniprotkb:D3DM12 intact:EBI-17237|uniprotkb:D6VSK9|ensemblfungi:YDR227W psi-mi:nu157_yeast(display_long)|uniprotkb:YER105C(locus name)|uniprotkb:NUP157(gene name)|psi-mi:NUP157(display_short)|uniprotkb:Nuclear pore protein NUP157(gene name synonym) psi-mi:sir4_yeast(display_long)|uniprotkb:STE9(gene name synonym)|uniprotkb:SIR4(gene name)|psi-mi:SIR4(display_short)|uniprotkb:ASD1(gene name synonym)|uniprotkb:UTH2(gene name synonym)|uniprotkb:YDR227W(locus name)|uniprotkb:YD9934.12(orf name)|uniprotkb:Silent information regulator 4(gene name synonym) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879814|imex:IM-20939-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER105C(gene)|ensemblfungi:YER105C_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:4MHC|refseq:NP_011031.1|sgd:S000000907|mint:P40064|dip:DIP-846N refseq:NP_010513.1|sgd:S000002635|ensemblfungi:YDR227W(gene)|ensemblfungi:YDR227W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR031556|rcsb pdb:1NYH|rcsb pdb:1PL5|rcsb pdb:4IAO|rcsb pdb:6QSZ|rcsb pdb:6QTM|rcsb pdb:6RR0|rcsb pdb:6RRV|dip:DIP-33N|mint:P11978 - - crc64:9C698765964F094E figure legend:Fig. 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:vKznZjOxKUw5Bo+4LemfCkzdBxg559292 rogid:C1HZEbdzRxwODKN1FHzmhYMCl+M559292 intact-crc:F129B5536EA6583F|rigid:PcIctpzyXhtVZ2vFAhOhFHd3Y8o false protein a tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P11978 uniprotkb:P38181 intact:EBI-17237|uniprotkb:D6VSK9|ensemblfungi:YDR227W intact:EBI-11756|ensemblfungi:YBL079W|uniprotkb:D6VPS4 psi-mi:sir4_yeast(display_long)|uniprotkb:STE9(gene name synonym)|uniprotkb:SIR4(gene name)|psi-mi:SIR4(display_short)|uniprotkb:ASD1(gene name synonym)|uniprotkb:UTH2(gene name synonym)|uniprotkb:YDR227W(locus name)|uniprotkb:YD9934.12(orf name)|uniprotkb:Silent information regulator 4(gene name synonym) psi-mi:nu170_yeast(display_long)|uniprotkb:NUP170(gene name)|psi-mi:NUP170(display_short)|uniprotkb:NLE3(gene name synonym)|uniprotkb:YBL079W(locus name)|uniprotkb:YBL0725(orf name)|uniprotkb:Nuclear pore protein NUP170(gene name synonym) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879835|imex:IM-20939-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010513.1|sgd:S000002635|ensemblfungi:YDR227W(gene)|ensemblfungi:YDR227W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR031556|rcsb pdb:1NYH|rcsb pdb:1PL5|rcsb pdb:4IAO|rcsb pdb:6QSZ|rcsb pdb:6QTM|rcsb pdb:6RR0|rcsb pdb:6RRV|dip:DIP-33N|mint:P11978 ensemblfungi:YBL079W(gene)|ensemblfungi:YBL079W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006342"|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:3I5P|rcsb pdb:3I5Q|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|refseq:NP_009474.1|sgd:S000000175|mint:P38181|dip:DIP-2450N - crc64:9C698765964F094E crc64:3BEA65DAA2A5F99A figure legend:Supp Fig. 7D|comment:Interactions of Nup170 with Sir4 are enhanced in M-phase-arrested cells|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:C1HZEbdzRxwODKN1FHzmhYMCl+M559292 rogid:6CjNCgT5bb3uX7koAOPjJcaoW/Q559292 intact-crc:A1B7E685E3A5148B|rigid:wY9lOS3cxjPJzKMWgPhcm3lwtuE false myc tag:?-? protein a tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P11978 uniprotkb:P38181 intact:EBI-17237|uniprotkb:D6VSK9|ensemblfungi:YDR227W intact:EBI-11756|ensemblfungi:YBL079W|uniprotkb:D6VPS4 psi-mi:sir4_yeast(display_long)|uniprotkb:STE9(gene name synonym)|uniprotkb:SIR4(gene name)|psi-mi:SIR4(display_short)|uniprotkb:ASD1(gene name synonym)|uniprotkb:UTH2(gene name synonym)|uniprotkb:YDR227W(locus name)|uniprotkb:YD9934.12(orf name)|uniprotkb:Silent information regulator 4(gene name synonym) psi-mi:nu170_yeast(display_long)|uniprotkb:NUP170(gene name)|psi-mi:NUP170(display_short)|uniprotkb:NLE3(gene name synonym)|uniprotkb:YBL079W(locus name)|uniprotkb:YBL0725(orf name)|uniprotkb:Nuclear pore protein NUP170(gene name synonym) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879797|imex:IM-20939-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010513.1|sgd:S000002635|ensemblfungi:YDR227W(gene)|ensemblfungi:YDR227W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR031556|rcsb pdb:1NYH|rcsb pdb:1PL5|rcsb pdb:4IAO|rcsb pdb:6QSZ|rcsb pdb:6QTM|rcsb pdb:6RR0|rcsb pdb:6RRV|dip:DIP-33N|mint:P11978 ensemblfungi:YBL079W(gene)|ensemblfungi:YBL079W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006342"|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:3I5P|rcsb pdb:3I5Q|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|refseq:NP_009474.1|sgd:S000000175|mint:P38181|dip:DIP-2450N - crc64:9C698765964F094E crc64:3BEA65DAA2A5F99A figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:C1HZEbdzRxwODKN1FHzmhYMCl+M559292 rogid:6CjNCgT5bb3uX7koAOPjJcaoW/Q559292 intact-crc:BC0B4E7DD61F093D|rigid:wY9lOS3cxjPJzKMWgPhcm3lwtuE false protein a tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q03790 uniprotkb:P38181 intact:EBI-27321|uniprotkb:D6VZX4|ensemblfungi:YMR153W intact:EBI-11756|ensemblfungi:YBL079W|uniprotkb:D6VPS4 psi-mi:nup53_yeast(display_long)|uniprotkb:Nuclear pore protein NUP53(gene name synonym)|uniprotkb:NUP53(gene name)|psi-mi:NUP53(display_short)|uniprotkb:YMR153W(locus name)|uniprotkb:YM8520.02(orf name) psi-mi:nu170_yeast(display_long)|uniprotkb:NUP170(gene name)|psi-mi:NUP170(display_short)|uniprotkb:NLE3(gene name synonym)|uniprotkb:YBL079W(locus name)|uniprotkb:YBL0725(orf name)|uniprotkb:Nuclear pore protein NUP170(gene name synonym) psi-mi:"MI:0400"(affinity technology) Van et al. (2013) pubmed:23452847|imex:IM-20939 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6879735|imex:IM-20939-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013873.1|sgd:S000004762|dip:DIP-1467N|ensemblfungi:YMR153W(gene)|ensemblfungi:YMR153W_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0072417"(response to spindle checkpoint signaling)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|rcsb pdb:3W3Y|rcsb pdb:5UAZ ensemblfungi:YBL079W(gene)|ensemblfungi:YBL079W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003682"(chromatin binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006342"|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|rcsb pdb:3I5P|rcsb pdb:3I5Q|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|refseq:NP_009474.1|sgd:S000000175|mint:P38181|dip:DIP-2450N - crc64:2ECE0C561D27E523 crc64:3BEA65DAA2A5F99A figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/07/05 2014/10/16 rogid:csq2oRFswkgY2JkT+dmz/L7Zpfk559292 rogid:6CjNCgT5bb3uX7koAOPjJcaoW/Q559292 intact-crc:E1CE17022B13CD57|rigid:Am99G7iLNAmbIBo+YV4LydKtOjg false green fluorescent protein tag:?-? protein a tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)