#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NP84	uniprotkb:O43508	intact:EBI-2851995|uniprotkb:Q9HCS0|uniprotkb:D3DUA6|ensembl:ENSP00000326737	intact:EBI-6932080|ensembl:ENSP00000293825|uniprotkb:Q8IZK7|uniprotkb:Q8WUZ7	psi-mi:tnr12_human(display_long)|uniprotkb:TNFRSF12A(gene name)|psi-mi:TNFRSF12A(display_short)|uniprotkb:FN14(gene name synonym)|uniprotkb:Fibroblast growth factor-inducible immediate-early response protein 14(gene name synonym)|uniprotkb:Tweak-receptor(gene name synonym)	psi-mi:tnf12_human(display_long)|uniprotkb:TNFSF12(gene name)|psi-mi:TNFSF12(display_short)|uniprotkb:APO3L(gene name synonym)|uniprotkb:DR3LG(gene name synonym)|uniprotkb:APO3 ligand(gene name synonym)|uniprotkb:TNF-related weak inducer of apoptosis(gene name synonym)|uniprotkb:UNQ181/PRO207(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Pellegrini et al. (2013)	mint:fj-12-0925|pubmed:23438059|mint:MINT-8415037	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8445660|mint:MINT-8415099	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057723.1|ensembl:ENSG00000006327(gene)|ensembl:ENST00000326577(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR022316|rcsb pdb:2EQP|rcsb pdb:2KMZ|rcsb pdb:2RPJ|reactome:R-HSA-5668541|reactome:R-HSA-5676594|mint:MINT-8415102(identity)	go:"GO:0005164"(tumor necrosis factor receptor binding)|ensembl:ENSG00000239697(gene)|ensembl:ENST00000293825(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:4HT1|reactome:R-HSA-5668541|reactome:R-HSA-5676594|refseq:NP_003800.1|refseq:NP_742086.1|mint:MINT-8415101(identity)	-	comment:"Stoichiometry: 1.3"	comment:"Stoichiometry: 3.1"	figure legend:f2c|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:65.0x10^-9(molar)	2013/02/21	2022/01/21	rogid:Dt8beNQk0ZQIvgZNCOWKnMvO/+g9606	rogid:c+GDw07mUuZ3PUZdawQjYppMRpc9606	intact-crc:A74AC391058B5724|rigid:EU/9p1uN68Eb04JROSnlAV9xuo0	false	-	his tag:?-?(MINT-8415115)	1	3	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6SIX7	uniprotkb:O43508	intact:EBI-8445678|intact:MINT-8415055	intact:EBI-6932080|ensembl:ENSP00000293825|uniprotkb:Q8IZK7|uniprotkb:Q8WUZ7	psi-mi:q6six7_xenla(display_long)|uniprotkb:tnfrsf12a.L(gene name)|psi-mi:tnfrsf12a.L(display_short)|uniprotkb:Fn14(gene name synonym)|uniprotkb:tnfrsf12a(gene name synonym)	psi-mi:tnf12_human(display_long)|uniprotkb:TNFSF12(gene name)|psi-mi:TNFSF12(display_short)|uniprotkb:APO3L(gene name synonym)|uniprotkb:DR3LG(gene name synonym)|uniprotkb:APO3 ligand(gene name synonym)|uniprotkb:TNF-related weak inducer of apoptosis(gene name synonym)|uniprotkb:UNQ181/PRO207(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Pellegrini et al. (2013)	mint:fj-12-0925|pubmed:23438059|mint:MINT-8415037	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8445688|mint:MINT-8415120	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2KN0|interpro:IPR022316|refseq:NP_001083640.1|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|mint:MINT-8415127(identity)	go:"GO:0005164"(tumor necrosis factor receptor binding)|ensembl:ENSG00000239697(gene)|ensembl:ENST00000293825(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:4HT1|reactome:R-HSA-5668541|reactome:R-HSA-5676594|refseq:NP_003800.1|refseq:NP_742086.1|mint:MINT-8415123(identity)	-	comment:mint|comment:"Stoichiometry: 1.3"	comment:"Stoichiometry: 3.1"	figure legend:f2d|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.3x10^-6(molar)	2013/02/21	2022/01/21	rogid:1FFJwMnlBCZV1beDZ1nUqrh/FOI8355	rogid:c+GDw07mUuZ3PUZdawQjYppMRpc9606	intact-crc:4E12937A5BDF4F7C|rigid:UAa4bRfcVsu9JdCHvfxJ0VKY9rM	false	-	his tag:?-?(MINT-8415124)	1	3	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6SIX7	uniprotkb:O43508	intact:EBI-8445678|intact:MINT-8415055	intact:EBI-6932080|ensembl:ENSP00000293825|uniprotkb:Q8IZK7|uniprotkb:Q8WUZ7	psi-mi:q6six7_xenla(display_long)|uniprotkb:tnfrsf12a.L(gene name)|psi-mi:tnfrsf12a.L(display_short)|uniprotkb:Fn14(gene name synonym)|uniprotkb:tnfrsf12a(gene name synonym)	psi-mi:tnf12_human(display_long)|uniprotkb:TNFSF12(gene name)|psi-mi:TNFSF12(display_short)|uniprotkb:APO3L(gene name synonym)|uniprotkb:DR3LG(gene name synonym)|uniprotkb:APO3 ligand(gene name synonym)|uniprotkb:TNF-related weak inducer of apoptosis(gene name synonym)|uniprotkb:UNQ181/PRO207(orf name)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Pellegrini et al. (2013)	mint:fj-12-0925|pubmed:23438059|mint:MINT-8415037	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8445732|mint:MINT-8415133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2KN0|interpro:IPR022316|refseq:NP_001083640.1|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|mint:MINT-8415140(identity)	go:"GO:0005164"(tumor necrosis factor receptor binding)|ensembl:ENSG00000239697(gene)|ensembl:ENST00000293825(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:4HT1|reactome:R-HSA-5668541|reactome:R-HSA-5676594|refseq:NP_003800.1|refseq:NP_742086.1|mint:MINT-8415136(identity)	-	comment:mint	-	figure legend:f2b|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/21	2014/10/16	rogid:1FFJwMnlBCZV1beDZ1nUqrh/FOI8355	rogid:c+GDw07mUuZ3PUZdawQjYppMRpc9606	intact-crc:848B55E128464AEF|rigid:UAa4bRfcVsu9JdCHvfxJ0VKY9rM	false	-	fusion protein:?-?(MINT-8415137)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O43508	uniprotkb:Q9NP84	intact:EBI-6932080|ensembl:ENSP00000293825|uniprotkb:Q8IZK7|uniprotkb:Q8WUZ7	intact:EBI-2851995|uniprotkb:Q9HCS0|uniprotkb:D3DUA6|ensembl:ENSP00000326737	psi-mi:tnf12_human(display_long)|uniprotkb:TNFSF12(gene name)|psi-mi:TNFSF12(display_short)|uniprotkb:APO3L(gene name synonym)|uniprotkb:DR3LG(gene name synonym)|uniprotkb:APO3 ligand(gene name synonym)|uniprotkb:TNF-related weak inducer of apoptosis(gene name synonym)|uniprotkb:UNQ181/PRO207(orf name)	psi-mi:tnr12_human(display_long)|uniprotkb:TNFRSF12A(gene name)|psi-mi:TNFRSF12A(display_short)|uniprotkb:FN14(gene name synonym)|uniprotkb:Fibroblast growth factor-inducible immediate-early response protein 14(gene name synonym)|uniprotkb:Tweak-receptor(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Pellegrini et al. (2013)	mint:fj-12-0925|pubmed:23438059|mint:MINT-8415037	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8445745|mint:MINT-8415146	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005164"(tumor necrosis factor receptor binding)|ensembl:ENSG00000239697(gene)|ensembl:ENST00000293825(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:4HT1|reactome:R-HSA-5668541|reactome:R-HSA-5676594|refseq:NP_003800.1|refseq:NP_742086.1|mint:MINT-8415150(identity)	refseq:NP_057723.1|ensembl:ENSG00000006327(gene)|ensembl:ENST00000326577(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR022316|rcsb pdb:2EQP|rcsb pdb:2KMZ|rcsb pdb:2RPJ|reactome:R-HSA-5668541|reactome:R-HSA-5676594|mint:MINT-8415148(identity)	-	-	-	figure legend:f2b|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/02/21	2014/10/16	rogid:c+GDw07mUuZ3PUZdawQjYppMRpc9606	rogid:Dt8beNQk0ZQIvgZNCOWKnMvO/+g9606	intact-crc:64519EEB3C78F18A|rigid:EU/9p1uN68Eb04JROSnlAV9xuo0	false	fusion protein:?-?(MINT-8415151)	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0396"(predetermined participant)