#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:B8PZP6 uniprotkb:Q4R4G2 intact:EBI-6601253 intact:EBI-6600948 psi-mi:b8pzp6_9mono(display_long)|uniprotkb:P/V/C(gene name synonym)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:q4r4g2_chlae(display_long)|uniprotkb:STAT1 alpha(gene name)|psi-mi:STAT1 alpha(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11234(measd)|taxid:11234("Measles virus (strain Dublin) (MeV)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601029 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR028243 go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|interpro:IPR035859|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022752|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR038295|interpro:IPR036535|interpro:IPR036860 - - - figure legend:5|comment:Weak association.|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M11234 rogid:tvFFTVF7PHT3BGaSnAkHO/UIWMg9534 intact-crc:6800C8D79DD7F5AB|rigid:MaPPWVJAidiJ8TOJkG7Wmx1ZMZ4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:B8PZP6 uniprotkb:Q4R4G0 intact:EBI-6601253 intact:EBI-6600988 psi-mi:b8pzp6_9mono(display_long)|uniprotkb:P/V/C(gene name synonym)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:q4r4g0_chlae(display_long)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11234(measd)|taxid:11234("Measles virus (strain Dublin) (MeV)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601029 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR028243 go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|interpro:IPR035854|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022756|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR036535|interpro:IPR036860 - - - figure legend:5|comment:Weak association.|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M11234 rogid:JAJ26QMU/duIoH2WqkJ739Mw/OM9534 intact-crc:6800C8D79DD7F5AB|rigid:MaPPWVJAidiJ8TOJkG7Wmx1ZMZ4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6600912 uniprotkb:Q4R4G0 - intact:EBI-6600988 psi-mi:proteinv_cdvo(display_short)|psi-mi:EBI-6600912(display_long) psi-mi:q4r4g0_chlae(display_long)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11233(cdvo)|taxid:11233("Canine distemper virus (strain Onderstepoort) (CDV)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601063 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|interpro:IPR035854|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022756|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR036535|interpro:IPR036860 - comment:personal communication, submitted by MD Baron, michael.baron@pirbright.ac.uk - figure legend:5|comment:Weak association.|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:xODM3QLAM19kiGQIjLsaDllb04E11233 rogid:JAJ26QMU/duIoH2WqkJ739Mw/OM9534 intact-crc:4AF41F72E011F1BD|rigid:Fdq0EWS8rtl5Rff3N1LhuGLSMvw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6600912 uniprotkb:Q4R4G2 - intact:EBI-6600948 psi-mi:proteinv_cdvo(display_short)|psi-mi:EBI-6600912(display_long) psi-mi:q4r4g2_chlae(display_long)|uniprotkb:STAT1 alpha(gene name)|psi-mi:STAT1 alpha(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11233(cdvo)|taxid:11233("Canine distemper virus (strain Onderstepoort) (CDV)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601063 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|interpro:IPR035859|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022752|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR038295|interpro:IPR036535|interpro:IPR036860 - comment:personal communication, submitted by MD Baron, michael.baron@pirbright.ac.uk - figure legend:5|comment:Weak association.|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:xODM3QLAM19kiGQIjLsaDllb04E11233 rogid:tvFFTVF7PHT3BGaSnAkHO/UIWMg9534 intact-crc:4AF41F72E011F1BD|rigid:Fdq0EWS8rtl5Rff3N1LhuGLSMvw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03340 uniprotkb:Q4R4G2 intact:EBI-6601013 intact:EBI-6600948 psi-mi:v_rindr(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:q4r4g2_chlae(display_long)|uniprotkb:STAT1 alpha(gene name)|psi-mi:STAT1 alpha(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:36409(rindr)|taxid:36409("Rinderpest virus (strain RBOK)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601007 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR028243 go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|interpro:IPR035859|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022752|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR038295|interpro:IPR036535|interpro:IPR036860 - - - figure legend:5|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:DhQ0H3Znqr/WPlQbJLwZYL+Tve036409 rogid:tvFFTVF7PHT3BGaSnAkHO/UIWMg9534 intact-crc:9E4C533A054E712D|rigid:C9Bb7OCapaoKZZ4GZiaV2z7X24c false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03340 uniprotkb:Q4R4G0 intact:EBI-6601013 intact:EBI-6600988 psi-mi:v_rindr(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:q4r4g0_chlae(display_long)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:36409(rindr)|taxid:36409("Rinderpest virus (strain RBOK)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601007 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR028243 go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|interpro:IPR035854|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022756|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR036535|interpro:IPR036860 - - - figure legend:5|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:DhQ0H3Znqr/WPlQbJLwZYL+Tve036409 rogid:JAJ26QMU/duIoH2WqkJ739Mw/OM9534 intact-crc:9E4C533A054E712D|rigid:C9Bb7OCapaoKZZ4GZiaV2z7X24c false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6599589 uniprotkb:Q4R4G0 - intact:EBI-6600988 psi-mi:v_rindsa(display_short)|psi-mi:EBI-6599589(display_long) psi-mi:q4r4g0_chlae(display_long)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11241(rind-sa)|taxid:11241("Rinderpest virus (strain Sa) (RDV)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6600984 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|interpro:IPR035854|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022756|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR036535|interpro:IPR036860 - comment:personal communication and submission, Dr MD Baron michael.baron@pirbright.ac.uk - figure legend:5|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:63sRgCQNokOGPzH2XXrn2H7UaFQ11241 rogid:JAJ26QMU/duIoH2WqkJ739Mw/OM9534 intact-crc:F491DE2E6AD0B39F|rigid:+s1TlcgE0TTOOG2JoL/5LAvRyUA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6599589 uniprotkb:Q4R4G2 - intact:EBI-6600948 psi-mi:v_rindsa(display_short)|psi-mi:EBI-6599589(display_long) psi-mi:q4r4g2_chlae(display_long)|uniprotkb:STAT1 alpha(gene name)|psi-mi:STAT1 alpha(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11241(rind-sa)|taxid:11241("Rinderpest virus (strain Sa) (RDV)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6600984 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|interpro:IPR035859|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022752|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR038295|interpro:IPR036535|interpro:IPR036860 - comment:personal communication and submission, Dr MD Baron michael.baron@pirbright.ac.uk - figure legend:5|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:63sRgCQNokOGPzH2XXrn2H7UaFQ11241 rogid:tvFFTVF7PHT3BGaSnAkHO/UIWMg9534 intact-crc:F491DE2E6AD0B39F|rigid:+s1TlcgE0TTOOG2JoL/5LAvRyUA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6TV27 uniprotkb:Q4R4G2 intact:EBI-6601056 intact:EBI-6600948 psi-mi:q6tv27_9mono(display_long) psi-mi:q4r4g2_chlae(display_long)|uniprotkb:STAT1 alpha(gene name)|psi-mi:STAT1 alpha(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11232(canine distemper virus)|taxid:11232(Canine distemper virus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601050 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR028243 go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|interpro:IPR035859|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022752|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR038295|interpro:IPR036535|interpro:IPR036860 - - - figure legend:5|comment:Weak association|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:uPZp6+sWQnFJVduxQ0OrelD/BAY11232 rogid:tvFFTVF7PHT3BGaSnAkHO/UIWMg9534 intact-crc:7DD02543975572F6|rigid:1ZZ42p6Z5O7Iana7eqHLEDEjEGs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6TV27 uniprotkb:Q4R4G0 intact:EBI-6601056 intact:EBI-6600988 psi-mi:q6tv27_9mono(display_long) psi-mi:q4r4g0_chlae(display_long)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11232(canine distemper virus)|taxid:11232(Canine distemper virus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601050 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR028243 go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|interpro:IPR035854|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022756|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR036535|interpro:IPR036860 - - - figure legend:5|comment:Weak association|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:uPZp6+sWQnFJVduxQ0OrelD/BAY11232 rogid:JAJ26QMU/duIoH2WqkJ739Mw/OM9534 intact-crc:7DD02543975572F6|rigid:1ZZ42p6Z5O7Iana7eqHLEDEjEGs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6600906 uniprotkb:Q4R4G0 - intact:EBI-6600988 psi-mi:proteinv_measd(display_short)|psi-mi:EBI-6600906(display_long) psi-mi:q4r4g0_chlae(display_long)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11234(measd)|taxid:11234("Measles virus (strain Dublin) (MeV)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601025 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|interpro:IPR035854|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022756|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR036535|interpro:IPR036860 - - - figure legend:5|comment:Weak association|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:Y24TmQ01XjM8+5/BB0E/X382GDE11234 rogid:JAJ26QMU/duIoH2WqkJ739Mw/OM9534 intact-crc:A9419A4E17C1F603|rigid:Kj1VVNUHKIeW6gveJ2ducuvlE74 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6600906 uniprotkb:Q4R4G2 - intact:EBI-6600948 psi-mi:proteinv_measd(display_short)|psi-mi:EBI-6600906(display_long) psi-mi:q4r4g2_chlae(display_long)|uniprotkb:STAT1 alpha(gene name)|psi-mi:STAT1 alpha(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11234(measd)|taxid:11234("Measles virus (strain Dublin) (MeV)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601025 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|interpro:IPR035859|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022752|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR038295|interpro:IPR036535|interpro:IPR036860 - - - figure legend:5|comment:Weak association|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:Y24TmQ01XjM8+5/BB0E/X382GDE11234 rogid:tvFFTVF7PHT3BGaSnAkHO/UIWMg9534 intact-crc:A9419A4E17C1F603|rigid:Kj1VVNUHKIeW6gveJ2ducuvlE74 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5ZER6 uniprotkb:Q4R4G0 intact:EBI-6601044 intact:EBI-6600988 psi-mi:q5zer6_pprv(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:q4r4g0_chlae(display_long)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:2593991(Peste-des-petits-ruminants virus)|taxid:2593991(Peste-des-petits-ruminants virus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601035 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028243|refseq:YP_133823.2 go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|interpro:IPR035854|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022756|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR036535|interpro:IPR036860 - - - figure legend:5|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:RqP4WNW0T/qMbdXqycRCi4MPDUM2593991 rogid:JAJ26QMU/duIoH2WqkJ739Mw/OM9534 intact-crc:ED14D5FB6ED9F136|rigid:An0Qf2iOJLhO3jodygzdQ0qfH5A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5ZER6 uniprotkb:Q4R4G2 intact:EBI-6601044 intact:EBI-6600948 psi-mi:q5zer6_pprv(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:q4r4g2_chlae(display_long)|uniprotkb:STAT1 alpha(gene name)|psi-mi:STAT1 alpha(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:2593991(Peste-des-petits-ruminants virus)|taxid:2593991(Peste-des-petits-ruminants virus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601035 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028243|refseq:YP_133823.2 go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|interpro:IPR035859|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR000980(SH2 motif)|interpro:IPR022752|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR038295|interpro:IPR036535|interpro:IPR036860 - - - figure legend:5|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:RqP4WNW0T/qMbdXqycRCi4MPDUM2593991 rogid:tvFFTVF7PHT3BGaSnAkHO/UIWMg9534 intact-crc:ED14D5FB6ED9F136|rigid:An0Qf2iOJLhO3jodygzdQ0qfH5A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6599589 uniprotkb:P29597 - intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885 psi-mi:v_rindsa(display_short)|psi-mi:EBI-6599589(display_long) psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11241(rind-sa)|taxid:11241("Rinderpest virus (strain Sa) (RDV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601081 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462 - comment:personal communication and submission, Dr MD Baron michael.baron@pirbright.ac.uk - figure legend:9A|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:63sRgCQNokOGPzH2XXrn2H7UaFQ11241 rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606 intact-crc:8DBA5E7449BE5E45|rigid:aolKIN2zSRWMqh9ODee6uAaNYj0 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-6599589 uniprotkb:P23458 - intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204|ensembl:ENSP00000499884|ensembl:ENSP00000499900|ensembl:ENSP00000500296|ensembl:ENSP00000500485|ensembl:ENSP00000500841 psi-mi:v_rindsa(display_short)|psi-mi:EBI-6599589(display_long) psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11241(rind-sa)|taxid:11241("Rinderpest virus (strain Sa) (RDV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601085 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001308785.1|refseq:NP_002218.2|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|dip:DIP-133N|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-909733|ensembl:ENSG00000162434(gene)|ensembl:ENST00000342505(transcript)|ensembl:ENST00000671929(transcript)|ensembl:ENST00000671954(transcript)|ensembl:ENST00000672179(transcript)|ensembl:ENST00000672247(transcript)|ensembl:ENST00000672434(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958 - comment:personal communication and submission, Dr MD Baron michael.baron@pirbright.ac.uk - figure legend:9A|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:63sRgCQNokOGPzH2XXrn2H7UaFQ11241 rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606 intact-crc:A0FFC2EF1016E287|rigid:c7arX+J1HxtgxAoE2ZqD+1KcLmY false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-6599589 uniprotkb:P29597 - intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885 psi-mi:v_rindsa(display_short)|psi-mi:EBI-6599589(display_long) psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11241(rind-sa)|taxid:11241("Rinderpest virus (strain Sa) (RDV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601077 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462 - comment:personal communication and submission, Dr MD Baron michael.baron@pirbright.ac.uk - figure legend:9A|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:63sRgCQNokOGPzH2XXrn2H7UaFQ11241 rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606 intact-crc:75D2CA4CFE6EDB3A|rigid:aolKIN2zSRWMqh9ODee6uAaNYj0 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-6599589 uniprotkb:P23458 - intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204|ensembl:ENSP00000499884|ensembl:ENSP00000499900|ensembl:ENSP00000500296|ensembl:ENSP00000500485|ensembl:ENSP00000500841 psi-mi:v_rindsa(display_short)|psi-mi:EBI-6599589(display_long) psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11241(rind-sa)|taxid:11241("Rinderpest virus (strain Sa) (RDV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601089 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001308785.1|refseq:NP_002218.2|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|dip:DIP-133N|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-909733|ensembl:ENSG00000162434(gene)|ensembl:ENST00000342505(transcript)|ensembl:ENST00000671929(transcript)|ensembl:ENST00000671954(transcript)|ensembl:ENST00000672179(transcript)|ensembl:ENST00000672247(transcript)|ensembl:ENST00000672434(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958 - comment:personal communication and submission, Dr MD Baron michael.baron@pirbright.ac.uk - figure legend:9A|curation depth:mimix curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2013/04/05 2014/10/16 rogid:63sRgCQNokOGPzH2XXrn2H7UaFQ11241 rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606 intact-crc:589756D7A7C667F8|rigid:c7arX+J1HxtgxAoE2ZqD+1KcLmY false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P29597 uniprotkb:Q6TV27 intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885 intact:EBI-6601056 psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short) psi-mi:q6tv27_9mono(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11232(canine distemper virus)|taxid:11232(Canine distemper virus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462 go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR028243 - - - figure legend:9B|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606 rogid:uPZp6+sWQnFJVduxQ0OrelD/BAY11232 intact-crc:8702E2DB7671AC70|rigid:VgKYq0hGxoPZdHF3gbEtxwirGgo false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6TV27 uniprotkb:P23458 intact:EBI-6601056 intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204|ensembl:ENSP00000499884|ensembl:ENSP00000499900|ensembl:ENSP00000500296|ensembl:ENSP00000500485|ensembl:ENSP00000500841 psi-mi:q6tv27_9mono(display_long) psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11232(canine distemper virus)|taxid:11232(Canine distemper virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601160 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR028243 refseq:NP_001308785.1|refseq:NP_002218.2|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|dip:DIP-133N|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-909733|ensembl:ENSG00000162434(gene)|ensembl:ENST00000342505(transcript)|ensembl:ENST00000671929(transcript)|ensembl:ENST00000671954(transcript)|ensembl:ENST00000672179(transcript)|ensembl:ENST00000672247(transcript)|ensembl:ENST00000672434(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958 - - - figure legend:9C|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:uPZp6+sWQnFJVduxQ0OrelD/BAY11232 rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606 intact-crc:A32E314AD58431D3|rigid:1IiNIqIyKnF4hIwTMnkfkTJl43w false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-6599589 uniprotkb:P29597 - intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885 psi-mi:v_rindsa(display_short)|psi-mi:EBI-6599589(display_long) psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11241(rind-sa)|taxid:11241("Rinderpest virus (strain Sa) (RDV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462 - comment:personal communication and submission, Dr MD Baron michael.baron@pirbright.ac.uk - figure legend:9B|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:63sRgCQNokOGPzH2XXrn2H7UaFQ11241 rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606 intact-crc:164C56459B6F4972|rigid:aolKIN2zSRWMqh9ODee6uAaNYj0 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P23458 uniprotkb:B8PZP6 intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204|ensembl:ENSP00000499884|ensembl:ENSP00000499900|ensembl:ENSP00000500296|ensembl:ENSP00000500485|ensembl:ENSP00000500841 intact:EBI-6601253 psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym) psi-mi:b8pzp6_9mono(display_long)|uniprotkb:P/V/C(gene name synonym)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11234(measd)|taxid:11234("Measles virus (strain Dublin) (MeV)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308785.1|refseq:NP_002218.2|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|dip:DIP-133N|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-909733|ensembl:ENSG00000162434(gene)|ensembl:ENST00000342505(transcript)|ensembl:ENST00000671929(transcript)|ensembl:ENST00000671954(transcript)|ensembl:ENST00000672179(transcript)|ensembl:ENST00000672247(transcript)|ensembl:ENST00000672434(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958 go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR028243 - - - figure legend:9C|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M11234 intact-crc:E21D13869DDF0E6E|rigid:wAuI+q/rlS/tKr75l35Zs/ALAi4 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-6599589 uniprotkb:P23458 - intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204|ensembl:ENSP00000499884|ensembl:ENSP00000499900|ensembl:ENSP00000500296|ensembl:ENSP00000500485|ensembl:ENSP00000500841 psi-mi:v_rindsa(display_short)|psi-mi:EBI-6599589(display_long) psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11241(rind-sa)|taxid:11241("Rinderpest virus (strain Sa) (RDV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001308785.1|refseq:NP_002218.2|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|dip:DIP-133N|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-909733|ensembl:ENSG00000162434(gene)|ensembl:ENST00000342505(transcript)|ensembl:ENST00000671929(transcript)|ensembl:ENST00000671954(transcript)|ensembl:ENST00000672179(transcript)|ensembl:ENST00000672247(transcript)|ensembl:ENST00000672434(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958 - comment:personal communication and submission, Dr MD Baron michael.baron@pirbright.ac.uk - figure legend:9C|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:63sRgCQNokOGPzH2XXrn2H7UaFQ11241 rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606 intact-crc:3B087ADEC2C7F5B0|rigid:c7arX+J1HxtgxAoE2ZqD+1KcLmY false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-6600906 uniprotkb:P23458 - intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204|ensembl:ENSP00000499884|ensembl:ENSP00000499900|ensembl:ENSP00000500296|ensembl:ENSP00000500485|ensembl:ENSP00000500841 psi-mi:proteinv_measd(display_short)|psi-mi:EBI-6600906(display_long) psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11234(measd)|taxid:11234("Measles virus (strain Dublin) (MeV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001308785.1|refseq:NP_002218.2|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|dip:DIP-133N|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-909733|ensembl:ENSG00000162434(gene)|ensembl:ENST00000342505(transcript)|ensembl:ENST00000671929(transcript)|ensembl:ENST00000671954(transcript)|ensembl:ENST00000672179(transcript)|ensembl:ENST00000672247(transcript)|ensembl:ENST00000672434(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958 - - - figure legend:9C|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:Y24TmQ01XjM8+5/BB0E/X382GDE11234 rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606 intact-crc:EA6C539FF2DE3058|rigid:H5zscsc2xxj8u4yyd0KT2k33iDw false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P23458 uniprotkb:Q5ZER6 intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204|ensembl:ENSP00000499884|ensembl:ENSP00000499900|ensembl:ENSP00000500296|ensembl:ENSP00000500485|ensembl:ENSP00000500841 intact:EBI-6601044 psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym) psi-mi:q5zer6_pprv(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:2593991(Peste-des-petits-ruminants virus)|taxid:2593991(Peste-des-petits-ruminants virus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308785.1|refseq:NP_002218.2|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|dip:DIP-133N|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-909733|ensembl:ENSG00000162434(gene)|ensembl:ENST00000342505(transcript)|ensembl:ENST00000671929(transcript)|ensembl:ENST00000671954(transcript)|ensembl:ENST00000672179(transcript)|ensembl:ENST00000672247(transcript)|ensembl:ENST00000672434(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958 interpro:IPR028243|refseq:YP_133823.2 - - - figure legend:9C|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606 rogid:RqP4WNW0T/qMbdXqycRCi4MPDUM2593991 intact-crc:3CC12E317E3E396A|rigid:j1CUYi3/XoLzJmyflJ3s4kluOP0 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5ZER6 uniprotkb:P29597 intact:EBI-6601044 intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885 psi-mi:q5zer6_pprv(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:2593991(Peste-des-petits-ruminants virus)|taxid:2593991(Peste-des-petits-ruminants virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028243|refseq:YP_133823.2 refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462 - - - figure legend:9B|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:RqP4WNW0T/qMbdXqycRCi4MPDUM2593991 rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606 intact-crc:18EDFDA0DDCBA4C9|rigid:tir/xwt2fY789CT2JzuZDiPwYQc false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-6600912 uniprotkb:P23458 - intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204|ensembl:ENSP00000499884|ensembl:ENSP00000499900|ensembl:ENSP00000500296|ensembl:ENSP00000500485|ensembl:ENSP00000500841 psi-mi:proteinv_cdvo(display_short)|psi-mi:EBI-6600912(display_long) psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11233(cdvo)|taxid:11233("Canine distemper virus (strain Onderstepoort) (CDV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001308785.1|refseq:NP_002218.2|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|dip:DIP-133N|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-909733|ensembl:ENSG00000162434(gene)|ensembl:ENST00000342505(transcript)|ensembl:ENST00000671929(transcript)|ensembl:ENST00000671954(transcript)|ensembl:ENST00000672179(transcript)|ensembl:ENST00000672247(transcript)|ensembl:ENST00000672434(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958 - comment:personal communication, submitted by MD Baron, michael.baron@pirbright.ac.uk - figure legend:9C|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:xODM3QLAM19kiGQIjLsaDllb04E11233 rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606 intact-crc:A5340A8A58D1EA28|rigid:yBNZI7ERH6LI8AUXzMtXblyZTUo false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-6600912 uniprotkb:P29597 - intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885 psi-mi:proteinv_cdvo(display_short)|psi-mi:EBI-6600912(display_long) psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11233(cdvo)|taxid:11233("Canine distemper virus (strain Onderstepoort) (CDV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462 - comment:personal communication, submitted by MD Baron, michael.baron@pirbright.ac.uk - figure legend:9B|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:xODM3QLAM19kiGQIjLsaDllb04E11233 rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606 intact-crc:88702611017956EA|rigid:8QFW+y7oObrnN7gkrUtksAIt4Ic false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:B8PZP6 uniprotkb:P29597 intact:EBI-6601253 intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885 psi-mi:b8pzp6_9mono(display_long)|uniprotkb:P/V/C(gene name synonym)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11234(measd)|taxid:11234("Measles virus (strain Dublin) (MeV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR028243 refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462 - - - figure legend:9B|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M11234 rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606 intact-crc:CF593F1DC477B2AC|rigid:Qw4bzd67AY+OG+ovTV8l6XSstKg false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P23458 uniprotkb:Q03340 intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204|ensembl:ENSP00000499884|ensembl:ENSP00000499900|ensembl:ENSP00000500296|ensembl:ENSP00000500485|ensembl:ENSP00000500841 intact:EBI-6601013 psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym) psi-mi:v_rindr(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:36409(rindr)|taxid:36409("Rinderpest virus (strain RBOK)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308785.1|refseq:NP_002218.2|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|dip:DIP-133N|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-909733|ensembl:ENSG00000162434(gene)|ensembl:ENST00000342505(transcript)|ensembl:ENST00000671929(transcript)|ensembl:ENST00000671954(transcript)|ensembl:ENST00000672179(transcript)|ensembl:ENST00000672247(transcript)|ensembl:ENST00000672434(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958 go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR028243 - - - figure legend:9C|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606 rogid:DhQ0H3Znqr/WPlQbJLwZYL+Tve036409 intact-crc:7F302030F453C9F3|rigid:LDlgcLmXbu2TIBsSNh68aNlmLoE false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P29597 uniprotkb:Q03340 intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885 intact:EBI-6601013 psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short) psi-mi:v_rindr(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:36409(rindr)|taxid:36409("Rinderpest virus (strain RBOK)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462 go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR028243 - - - figure legend:9B|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606 rogid:DhQ0H3Znqr/WPlQbJLwZYL+Tve036409 intact-crc:5B1CF3A157A65450|rigid:G/DrejXGus1/TlIiP8JK8FDdJJY false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-6600906 uniprotkb:P29597 - intact:EBI-1383454|uniprotkb:Q6QB10|uniprotkb:Q96CH0|ensembl:ENSP00000264818|ensembl:ENSP00000431885 psi-mi:proteinv_measd(display_short)|psi-mi:EBI-6600906(display_long) psi-mi:tyk2_human(display_long)|uniprotkb:TYK2(gene name)|psi-mi:TYK2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chinnakannan et al. (2013) pubmed:23431397 taxid:11234(measd)|taxid:11234("Measles virus (strain Dublin) (MeV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6601117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003322.3|refseq:XP_011526547.1|dip:DIP-1062N|ensembl:ENSG00000105397(gene)|ensembl:ENST00000264818(transcript)|ensembl:ENST00000525621(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016045(Tyrosine protein kinase, non-receptor, TYK2, N-terminal)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P29597|rcsb pdb:3LXN|rcsb pdb:3LXP|interpro:IPR008266(Tyrosine protein kinase, active site)|rcsb pdb:3NYX|rcsb pdb:3NZ0|rcsb pdb:3ZON|rcsb pdb:4GFO|rcsb pdb:4GIH|rcsb pdb:4GII|rcsb pdb:4GJ2|rcsb pdb:4GJ3|rcsb pdb:4GVJ|rcsb pdb:4OLI|rcsb pdb:4PO6|rcsb pdb:4PY1|rcsb pdb:4WOV|rcsb pdb:5C01|rcsb pdb:5C03|rcsb pdb:5F1Z|rcsb pdb:5F20|rcsb pdb:5TKD|rcsb pdb:5WAL|rcsb pdb:6AAM|rcsb pdb:6DBK|rcsb pdb:6DBM|rcsb pdb:6NSL|rcsb pdb:6NZE|rcsb pdb:6NZF|rcsb pdb:6NZH|rcsb pdb:6NZP|rcsb pdb:6NZQ|rcsb pdb:6NZR|rcsb pdb:6OVA|rcsb pdb:6VNS|rcsb pdb:6VNV|rcsb pdb:6VNX|rcsb pdb:6VNY|rcsb pdb:6X8F|rcsb pdb:6X8G|rcsb pdb:7AX4|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-449836|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-8854691|reactome:R-HSA-8984722|reactome:R-HSA-9020591|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462 - - - figure legend:9B|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2013/04/05 2014/10/16 rogid:Y24TmQ01XjM8+5/BB0E/X382GDE11234 rogid:HH4VIIlFEIQtLoXSDzxmu9nBvZs9606 intact-crc:C7287F04AB768C9A|rigid:ML1CewHHL76vUZeThEc+/6nasNk false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)