#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P01317 uniprotkb:P01317 intact:EBI-3989070 intact:EBI-3989070 psi-mi:ins_bovin(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:ins_bovin(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:"MI:0872"(atomic force microscopy) Babenko et al. (2013) pubmed:23416304|mint:MINT-8413634|mint:d-12-02034r1 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8437822|mint:MINT-8413639 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-52901N|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0009306"(protein secretion)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032094"(response to food)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035938"(estradiol secretion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1903431"(positive regulation of cell maturation)|go:"GO:1903488"(negative regulation of lactation)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1903524"(positive regulation of blood circulation)|go:"GO:1903544"(response to butyrate)|go:"GO:1903576"(response to L-arginine)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|rcsb pdb:1APH|rcsb pdb:1BPH|rcsb pdb:1CPH|rcsb pdb:1DPH|rcsb pdb:1HO0|rcsb pdb:1PID|rcsb pdb:2A3G|rcsb pdb:2BN1|rcsb pdb:2BN3|rcsb pdb:2INS|rcsb pdb:2ZP6|rcsb pdb:4BS3|rcsb pdb:4E7T|rcsb pdb:4E7U|rcsb pdb:4E7V|rcsb pdb:4I5Y|rcsb pdb:4I5Z|rcsb pdb:4IDW|rcsb pdb:4IHN|rcsb pdb:4M4F|rcsb pdb:4M4H|rcsb pdb:4M4I|rcsb pdb:4M4J|rcsb pdb:4M4L|rcsb pdb:4M4M|rcsb pdb:5AZZ|rcsb pdb:5KQV|rcsb pdb:5MIZ|rcsb pdb:6KH9|rcsb pdb:6KHA|rcsb pdb:6OR0|rcsb pdb:6Q8Q|rcsb pdb:6QQ7|rcsb pdb:6QQG|rcsb pdb:6QRH|rcsb pdb:6QRK|rcsb pdb:6ZHB|rcsb pdb:6ZI8|rcsb pdb:7ELJ|rcsb pdb:6KH8|mint:MINT-8413641(identity) dip:DIP-52901N|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0009306"(protein secretion)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032094"(response to food)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035938"(estradiol secretion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1903431"(positive regulation of cell maturation)|go:"GO:1903488"(negative regulation of lactation)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1903524"(positive regulation of blood circulation)|go:"GO:1903544"(response to butyrate)|go:"GO:1903576"(response to L-arginine)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|rcsb pdb:1APH|rcsb pdb:1BPH|rcsb pdb:1CPH|rcsb pdb:1DPH|rcsb pdb:1HO0|rcsb pdb:1PID|rcsb pdb:2A3G|rcsb pdb:2BN1|rcsb pdb:2BN3|rcsb pdb:2INS|rcsb pdb:2ZP6|rcsb pdb:4BS3|rcsb pdb:4E7T|rcsb pdb:4E7U|rcsb pdb:4E7V|rcsb pdb:4I5Y|rcsb pdb:4I5Z|rcsb pdb:4IDW|rcsb pdb:4IHN|rcsb pdb:4M4F|rcsb pdb:4M4H|rcsb pdb:4M4I|rcsb pdb:4M4J|rcsb pdb:4M4L|rcsb pdb:4M4M|rcsb pdb:5AZZ|rcsb pdb:5KQV|rcsb pdb:5MIZ|rcsb pdb:6KH9|rcsb pdb:6KHA|rcsb pdb:6OR0|rcsb pdb:6Q8Q|rcsb pdb:6QQ7|rcsb pdb:6QQG|rcsb pdb:6QRH|rcsb pdb:6QRK|rcsb pdb:6ZHB|rcsb pdb:6ZI8|rcsb pdb:7ELJ|rcsb pdb:6KH8|mint:MINT-8413645(identity) - - - comment:mint|figure legend:f2a f2b f2c f2d f4d f4h taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/06 2014/10/16 rogid:CgQ4BPd2mlhYt73TJXbE6V9GJYs9913 rogid:CgQ4BPd2mlhYt73TJXbE6V9GJYs9913 intact-crc:BC221127D1B4CBAC|rigid:hUyIEGMcFAdui5udi+emCJNQyNc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00711 uniprotkb:P00711 intact:EBI-7080486|intact:MINT-1487560|uniprotkb:Q95NE4|uniprotkb:Q3T111 intact:EBI-7080486|intact:MINT-1487560|uniprotkb:Q95NE4|uniprotkb:Q3T111 psi-mi:lalba_bovin(display_long)|uniprotkb:LALBA(gene name)|psi-mi:LALBA(display_short)|uniprotkb:ALACTA(gene name synonym)|uniprotkb:Lactose synthase B protein(gene name synonym) psi-mi:lalba_bovin(display_long)|uniprotkb:LALBA(gene name)|psi-mi:LALBA(display_short)|uniprotkb:ALACTA(gene name synonym)|uniprotkb:Lactose synthase B protein(gene name synonym) psi-mi:"MI:0872"(atomic force microscopy) Babenko et al. (2013) pubmed:23416304|mint:MINT-8413634|mint:d-12-02034r1 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8437879|mint:MINT-8413734 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P00711|go:"GO:0004461"(lactose synthase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005989"(lactose biosynthetic process)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0042802"(identical protein binding)|go:"GO:1903494"(response to dehydroepiandrosterone)|go:"GO:1903496"(response to 11-deoxycorticosterone)|rcsb pdb:1F6R|rcsb pdb:1F6S|rcsb pdb:1HFZ|rcsb pdb:2G4N|rcsb pdb:6IP9|interpro:IPR019799|interpro:IPR023346|refseq:NP_776803.1|interpro:IPR000545(Lactalbumin)|interpro:IPR001916(Glycoside hydrolase, family 22)|mint:MINT-8413738(identity) mint:P00711|go:"GO:0004461"(lactose synthase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005989"(lactose biosynthetic process)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0042802"(identical protein binding)|go:"GO:1903494"(response to dehydroepiandrosterone)|go:"GO:1903496"(response to 11-deoxycorticosterone)|rcsb pdb:1F6R|rcsb pdb:1F6S|rcsb pdb:1HFZ|rcsb pdb:2G4N|rcsb pdb:6IP9|interpro:IPR019799|interpro:IPR023346|refseq:NP_776803.1|interpro:IPR000545(Lactalbumin)|interpro:IPR001916(Glycoside hydrolase, family 22)|mint:MINT-8413736(identity) - comment:mint|comment:homomint|function:Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins comment:mint|comment:homomint|function:Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins figure legend:f4c|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/06 2014/10/16 rogid:jEnBQQgOzSEaNmxGJLAV+KkbnGs9913 rogid:jEnBQQgOzSEaNmxGJLAV+KkbnGs9913 intact-crc:5D3C7C792B50192F|rigid:MdCDDLqiv0e0UnUzr+i9rARQ7Zw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00698 uniprotkb:P00698 intact:EBI-1029543|uniprotkb:Q90884|ensembl:ENSGALP00000016177|uniprotkb:B8YJN9|uniprotkb:B8YJP1|uniprotkb:B8YJT7|uniprotkb:B8YK79 intact:EBI-1029543|uniprotkb:Q90884|ensembl:ENSGALP00000016177|uniprotkb:B8YJN9|uniprotkb:B8YJP1|uniprotkb:B8YJT7|uniprotkb:B8YK79 psi-mi:lysc_chick(display_long)|uniprotkb:LYZ(gene name)|psi-mi:LYZ(display_short)|uniprotkb:1,4-beta-N-acetylmuramidase C(gene name synonym)|uniprotkb:Allergen Gal d IV(gene name synonym) psi-mi:lysc_chick(display_long)|uniprotkb:LYZ(gene name)|psi-mi:LYZ(display_short)|uniprotkb:1,4-beta-N-acetylmuramidase C(gene name synonym)|uniprotkb:Allergen Gal d IV(gene name synonym) psi-mi:"MI:0872"(atomic force microscopy) Babenko et al. (2013) pubmed:23416304|mint:MINT-8413634|mint:d-12-02034r1 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8437850|mint:MINT-8413724 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1BGI|rcsb pdb:1BHZ|rcsb pdb:1BVK|rcsb pdb:1BVX|rcsb pdb:1BWH|rcsb pdb:1BWI|rcsb pdb:1BWJ|rcsb pdb:1C08|rcsb pdb:1C10|rcsb pdb:1DPW|rcsb pdb:1DPX|rcsb pdb:1DQJ|rcsb pdb:1E8L|rcsb pdb:1F0W|rcsb pdb:1F10|rcsb pdb:1F3J|rcsb pdb:1FDL|rcsb pdb:1FLQ|rcsb pdb:1FLU|rcsb pdb:1FLW|rcsb pdb:1FLY|rcsb pdb:1FN5|rcsb pdb:1G7H|rcsb pdb:1G7I|rcsb pdb:1B2K|rcsb pdb:1G7J|rcsb pdb:1G7L|rcsb pdb:1G7M|rcsb pdb:1GPQ|rcsb pdb:1GWD|rcsb pdb:1GXV|rcsb pdb:1GXX|rcsb pdb:1H6M|rcsb pdb:1JIY|rcsb pdb:1JJ0|rcsb pdb:1JJ1|rcsb pdb:1JJ3|rcsb pdb:1JPO|rcsb pdb:1JTO|rcsb pdb:1JTT|rcsb pdb:1KIP|rcsb pdb:1KIQ|rcsb pdb:1KIR|rcsb pdb:1KXW|rcsb pdb:1KXX|rcsb pdb:1KXY|rcsb pdb:1LCN|rcsb pdb:1LJ3|rcsb pdb:1JIT|rcsb pdb:1LJ4|rcsb pdb:1LJE|rcsb pdb:1LJF|rcsb pdb:1LJG|rcsb pdb:1LJH|rcsb pdb:1LJI|rcsb pdb:1LJJ|rcsb pdb:1LJK|rcsb pdb:1LKR|rcsb pdb:1HC0|rcsb pdb:1HEL|rcsb pdb:1HEM|rcsb pdb:1HEN|rcsb pdb:1HEO|rcsb pdb:1HEP|rcsb pdb:1HEQ|rcsb pdb:1HER|rcsb pdb:1HEW|rcsb pdb:1HF4|rcsb pdb:1HSW|rcsb pdb:1HSX|rcsb pdb:1IC4|rcsb pdb:1IC5|rcsb pdb:1IC7|rcsb pdb:1IEE|rcsb pdb:1IO5|rcsb pdb:1IOQ|rcsb pdb:1IOR|rcsb pdb:1IOS|rcsb pdb:1IOT|rcsb pdb:1IR7|rcsb pdb:1IR8|rcsb pdb:1IR9|rcsb pdb:1J1O|rcsb pdb:1J1P|rcsb pdb:1J1X|rcsb pdb:1JA2|rcsb pdb:1H87|rcsb pdb:1JA4|rcsb pdb:1JA6|rcsb pdb:1JA7|rcsb pdb:1JIS|ensembl:ENSGALT00000016196(transcript)|go:"GO:0003796"(lysozyme activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016231"(beta-N-acetylglucosaminidase activity)|go:"GO:0016998"(cell wall macromolecule catabolic process)|ensembl:ENSGALG00000009963(gene)|go:"GO:0019835"(cytolysis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051672"(obsolete catabolism by organism of cell wall peptidoglycan in other organism)|interpro:IPR000974(Glycoside hydrolase, family 22, lysozyme)|interpro:IPR001916(Glycoside hydrolase, family 22)|interpro:IPR019799|interpro:IPR023346|interpro:IPR030056|rcsb pdb:132L|rcsb pdb:193L|rcsb pdb:194L|rcsb pdb:1A2Y|rcsb pdb:1AKI|rcsb pdb:1AT5|rcsb pdb:1AT6|rcsb pdb:1AZF|rcsb pdb:1B0D|rcsb pdb:1UIF|rcsb pdb:1UIG|rcsb pdb:1UIH|rcsb pdb:1UUZ|rcsb pdb:1V7S|rcsb pdb:1V7T|rcsb pdb:1VAT|rcsb pdb:1VAU|rcsb pdb:1UIE|rcsb pdb:1VDP|rcsb pdb:1VDQ|rcsb pdb:1VDS|rcsb pdb:1VDT|rcsb pdb:1VED|rcsb pdb:1VFB|rcsb pdb:1W6Z|rcsb pdb:1WTM|rcsb pdb:1WTN|rcsb pdb:1XEI|rcsb pdb:1XEJ|rcsb pdb:1XEK|rcsb pdb:1XFP|rcsb pdb:1XGP|rcsb pdb:1XGQ|rcsb pdb:1XGR|rcsb pdb:1XGT|rcsb pdb:1XGU|rcsb pdb:1YIK|rcsb pdb:1YIL|rcsb pdb:1YKX|rcsb pdb:1YKY|rcsb pdb:1YKZ|rcsb pdb:1LMA|rcsb pdb:1LPI|rcsb pdb:1LSA|rcsb pdb:1LSB|rcsb pdb:1LSC|rcsb pdb:1LSD|rcsb pdb:1LSE|rcsb pdb:1LSF|rcsb pdb:1LSG|rcsb pdb:1LSM|rcsb pdb:1LSN|rcsb pdb:1LSY|rcsb pdb:1LSZ|rcsb pdb:1LYO|rcsb pdb:1LYS|rcsb pdb:1LYZ|rcsb pdb:1LZ8|rcsb pdb:1LKS|rcsb pdb:1LZ9|rcsb pdb:1LZA|rcsb pdb:1LZB|rcsb pdb:1LZC|rcsb pdb:1LZD|rcsb pdb:1UA6|rcsb pdb:1UC0|rcsb pdb:1UCO|rcsb pdb:1UIA|rcsb pdb:1UIB|rcsb pdb:1UIC|rcsb pdb:1LZE|rcsb pdb:1LZG|rcsb pdb:1LZH|rcsb pdb:1LZN|rcsb pdb:1LZT|rcsb pdb:1MEL|rcsb pdb:1MLC|rcsb pdb:1N4F|rcsb pdb:1NBY|rcsb pdb:1NBZ|rcsb pdb:1NDG|rcsb pdb:1NDM|rcsb pdb:1P2C|rcsb pdb:1PS5|rcsb pdb:1QIO|rcsb pdb:1QTK|rcsb pdb:1RCM|rcsb pdb:1RFP|rcsb pdb:1RI8|rcsb pdb:1RJC|rcsb pdb:1SF4|rcsb pdb:1SF6|rcsb pdb:1SF7|rcsb pdb:1SFB|rcsb pdb:1SFG|rcsb pdb:1SQ2|rcsb pdb:1T3P|rcsb pdb:1T6V|rcsb pdb:1UID|rcsb pdb:1YL1|rcsb pdb:1YQV|rcsb pdb:1Z55|rcsb pdb:1ZMY|rcsb pdb:1ZV5|rcsb pdb:1ZVH|rcsb pdb:1ZVY|rcsb pdb:2A6U|rcsb pdb:2A7D|rcsb pdb:2A7F|rcsb pdb:2AUB|rcsb pdb:2B5Z|rcsb pdb:2BLX|rcsb pdb:2BLY|rcsb pdb:2BPU|rcsb pdb:2C8O|rcsb pdb:2C8P|rcsb pdb:2CDS|rcsb pdb:2CGI|rcsb pdb:2D4I|rcsb pdb:1YL0|rcsb pdb:2D4J|rcsb pdb:2D4K|rcsb pdb:2D6B|rcsb pdb:2D91|rcsb pdb:2DQD|rcsb pdb:2DQE|rcsb pdb:2DQC|rcsb pdb:2DQF|rcsb pdb:2DQG|rcsb pdb:2DQH|rcsb pdb:2DQI|rcsb pdb:2DQJ|rcsb pdb:2EIZ|rcsb pdb:2EKS|rcsb pdb:2EPE|rcsb pdb:2F2N|rcsb pdb:2F30|rcsb pdb:2F4A|rcsb pdb:2F4G|rcsb pdb:2FBB|rcsb pdb:2G4P|rcsb pdb:2G4Q|rcsb pdb:2H9J|rcsb pdb:2H9K|rcsb pdb:2HFM|rcsb pdb:2HS7|rcsb pdb:2HS9|rcsb pdb:2HSO|rcsb pdb:2HTX|rcsb pdb:2HU1|rcsb pdb:2HU3|rcsb pdb:2HUB|rcsb pdb:2I25|rcsb pdb:2I26|rcsb pdb:2I6Z|rcsb pdb:2IFF|rcsb pdb:2LYM|rcsb pdb:2LYO|rcsb pdb:2LYZ|rcsb pdb:2LZH|rcsb pdb:2LZT|rcsb pdb:2PC2|rcsb pdb:2Q0M|rcsb pdb:2VB1|rcsb pdb:2W1L|rcsb pdb:2W1M|rcsb pdb:2W1X|rcsb pdb:2W1Y|rcsb pdb:2WAR|rcsb pdb:2X0A|rcsb pdb:2XBR|rcsb pdb:2XBS|rcsb pdb:2XJW|rcsb pdb:2XTH|rcsb pdb:2YBH|rcsb pdb:2YBI|rcsb pdb:2YBJ|rcsb pdb:2YBL|rcsb pdb:2YBM|rcsb pdb:2YDG|rcsb pdb:2YSS|rcsb pdb:2YVB|rcsb pdb:2Z12|rcsb pdb:2Z18|rcsb pdb:2Z19|rcsb pdb:2ZNW|rcsb pdb:2YBN|rcsb pdb:2ZNX|rcsb pdb:2ZQ3|rcsb pdb:2ZYP|rcsb pdb:3A34|rcsb pdb:3A3Q|rcsb pdb:3A3R|rcsb pdb:3A67|rcsb pdb:3A6B|rcsb pdb:3A6C|rcsb pdb:3A8Z|rcsb pdb:3A90|rcsb pdb:3A91|rcsb pdb:3A92|rcsb pdb:3A93|rcsb pdb:3A94|rcsb pdb:3A95|rcsb pdb:3A96|rcsb pdb:3AGG|rcsb pdb:3AGH|rcsb pdb:3AGI|rcsb pdb:3AJN|rcsb pdb:3ATN|rcsb pdb:3ATO|rcsb pdb:3AW6|rcsb pdb:3AW7|rcsb pdb:3AZ4|rcsb pdb:3AZ5|rcsb pdb:3AZ6|rcsb pdb:3AZ7|rcsb pdb:3B6L|rcsb pdb:3B72|rcsb pdb:3D9A|rcsb pdb:3E3D|rcsb pdb:3EMS|rcsb pdb:3EXD|rcsb pdb:3F6Z|rcsb pdb:3G3A|rcsb pdb:3G3B|rcsb pdb:3HFM|rcsb pdb:3IJU|rcsb pdb:2ZQ4|rcsb pdb:3IJV|rcsb pdb:3J4G|rcsb pdb:3J6K|rcsb pdb:3KAM|rcsb pdb:3LYT|rcsb pdb:3LYZ|rcsb pdb:3LZT|rcsb pdb:3M18|rcsb pdb:3M3U|rcsb pdb:3MBE|rcsb pdb:3N9A|rcsb pdb:3N9C|rcsb pdb:3N9E|rcsb pdb:3OJP|rcsb pdb:3OK0|rcsb pdb:3OTP|rcsb pdb:3P4Z|rcsb pdb:3P64|rcsb pdb:3P65|rcsb pdb:3P66|rcsb pdb:3P68|rcsb pdb:3QE8|rcsb pdb:3QNG|rcsb pdb:3QY4|rcsb pdb:3LYO|rcsb pdb:3RNX|rcsb pdb:3RT5|rcsb pdb:3LYM|rcsb pdb:3WU7|rcsb pdb:3WU8|rcsb pdb:3WU9|rcsb pdb:4B49|rcsb pdb:3WUA|rcsb pdb:3WUL|rcsb pdb:3WUM|rcsb pdb:3WUN|rcsb pdb:4B4E|rcsb pdb:3WVX|rcsb pdb:3WVY|rcsb pdb:3WW5|rcsb pdb:3WW6|rcsb pdb:3WXT|rcsb pdb:3WXU|rcsb pdb:3ZEK|rcsb pdb:3ZVQ|rcsb pdb:4A7D|rcsb pdb:4A8A|rcsb pdb:4A8B|rcsb pdb:4AGA|rcsb pdb:4AXT|rcsb pdb:4B0D|rcsb pdb:4B1A|rcsb pdb:3RW8|rcsb pdb:3RZ4|rcsb pdb:3SP3|rcsb pdb:3T6U|rcsb pdb:3TMU|rcsb pdb:3TMV|rcsb pdb:3TMW|rcsb pdb:3TMX|rcsb pdb:3TXB|rcsb pdb:3TXD|rcsb pdb:3TXE|rcsb pdb:3TXF|rcsb pdb:3TXG|rcsb pdb:3TXH|rcsb pdb:3TXI|rcsb pdb:3TXJ|rcsb pdb:3TXK|rcsb pdb:3ULR|rcsb pdb:3W6A|rcsb pdb:3WL2|rcsb pdb:3WMK|rcsb pdb:3RU5|rcsb pdb:3WPJ|rcsb pdb:3WPK|rcsb pdb:3WPL|rcsb pdb:4DDC|rcsb pdb:4DT3|rcsb pdb:4E3U|rcsb pdb:4BAD|rcsb pdb:4BAF|rcsb pdb:4BAP|rcsb pdb:4BS7|rcsb pdb:4C3W|rcsb pdb:4CJ2|rcsb pdb:4D9Z|rcsb pdb:4DC4|rcsb pdb:4DD0|rcsb pdb:4DD1|rcsb pdb:4DD2|rcsb pdb:4DD3|rcsb pdb:4DD7|rcsb pdb:4DD9|rcsb pdb:4DDA|rcsb pdb:4DDB|rcsb pdb:4EOF|rcsb pdb:4B4I|rcsb pdb:4B4J|rcsb pdb:4FJR|rcsb pdb:4G49|rcsb pdb:4G4B|rcsb pdb:4G4C|rcsb pdb:4G4H|rcsb pdb:4GCB|rcsb pdb:4GCC|rcsb pdb:4GCD|rcsb pdb:4GCE|rcsb pdb:4GCF|rcsb pdb:4GLA|rcsb pdb:4GLV|rcsb pdb:4GN3|rcsb pdb:4GN4|rcsb pdb:4GN5|rcsb pdb:4H1P|rcsb pdb:4H8X|rcsb pdb:4H8Y|rcsb pdb:4H8Z|rcsb pdb:4H90|rcsb pdb:4H91|rcsb pdb:4ETE|rcsb pdb:4H92|rcsb pdb:4H93|rcsb pdb:4H94|rcsb pdb:4H9A|rcsb pdb:4ET9|rcsb pdb:4ETA|rcsb pdb:4ETB|rcsb pdb:4ETC|rcsb pdb:4ETD|rcsb pdb:4ET8|rcsb pdb:4H9B|rcsb pdb:4H9C|rcsb pdb:4H9E|rcsb pdb:4H9F|rcsb pdb:4H9H|rcsb pdb:4H9I|rcsb pdb:4HP0|rcsb pdb:4HPI|rcsb pdb:4HSF|rcsb pdb:4HTK|rcsb pdb:4HTN|rcsb pdb:4HTQ|rcsb pdb:4HV1|rcsb pdb:4HV2|rcsb pdb:4I8S|rcsb pdb:4IAS|rcsb pdb:4IAT|rcsb pdb:4II8|rcsb pdb:4J1A|rcsb pdb:4J1B|rcsb pdb:4J7V|rcsb pdb:4KXI|rcsb pdb:4LFP|rcsb pdb:4PPO|rcsb pdb:4LFX|rcsb pdb:4LGK|rcsb pdb:4LT0|rcsb pdb:4LT1|rcsb pdb:4LT2|rcsb pdb:4LT3|rcsb pdb:4LYB|rcsb pdb:4LYC|rcsb pdb:4LYM|rcsb pdb:4LYO|rcsb pdb:4LYT|rcsb pdb:4LYZ|rcsb pdb:4LZT|rcsb pdb:4M4O|rcsb pdb:4M6D|rcsb pdb:4MR1|rcsb pdb:4N0J|rcsb pdb:4N1C|rcsb pdb:4N1E|rcsb pdb:4N5R|rcsb pdb:4N8Z|rcsb pdb:4N9R|rcsb pdb:4NEB|rcsb pdb:4NFV|rcsb pdb:4NG1|rcsb pdb:4NG8|rcsb pdb:4NGI|rcsb pdb:4NGJ|rcsb pdb:4NGL|rcsb pdb:4NGO|rcsb pdb:4NGV|rcsb pdb:4NGW|rcsb pdb:4NGY|rcsb pdb:4NGZ|rcsb pdb:4NHI|rcsb pdb:4NHP|rcsb pdb:4NHQ|rcsb pdb:4NHS|rcsb pdb:4NHT|rcsb pdb:4NGK|rcsb pdb:4NIJ|rcsb pdb:4NSG|rcsb pdb:4NSH|rcsb pdb:4NSI|rcsb pdb:4NSJ|rcsb pdb:4NWE|rcsb pdb:4NWH|rcsb pdb:4NY5|rcsb pdb:4O34|rcsb pdb:4OOO|rcsb pdb:4OOT|rcsb pdb:4OWA|rcsb pdb:4OWB|rcsb pdb:4OWC|rcsb pdb:4OWE|rcsb pdb:4OWH|rcsb pdb:4P2E|rcsb pdb:4PGJ|rcsb pdb:4PHI|rcsb pdb:4WG7|rcsb pdb:4WL6|rcsb pdb:4WL7|rcsb pdb:4WLD|rcsb pdb:4WLT|rcsb pdb:4WLX|rcsb pdb:4WLY|rcsb pdb:4WM1|rcsb pdb:4WM2|rcsb pdb:4WM3|rcsb pdb:4WM4|rcsb pdb:4WM5|rcsb pdb:4WM6|rcsb pdb:4PRU|rcsb pdb:4QEQ|rcsb pdb:4QGZ|rcsb pdb:4QY9|rcsb pdb:4R0F|rcsb pdb:4R6C|rcsb pdb:4RDS|rcsb pdb:4RLM|rcsb pdb:4RLN|rcsb pdb:4RW1|rcsb pdb:4RW2|rcsb pdb:4TSA|rcsb pdb:4TSB|rcsb pdb:4TSC|rcsb pdb:4TTD|rcsb pdb:4PRQ|rcsb pdb:4TUN|rcsb pdb:4TWS|rcsb pdb:4U3X|rcsb pdb:4UWN|rcsb pdb:4UWU|rcsb pdb:4UWV|rcsb pdb:4W94|rcsb pdb:4W96|rcsb pdb:4WG1|rcsb pdb:4WMG|rcsb pdb:4WO6|rcsb pdb:4WO9|rcsb pdb:4WOA|rcsb pdb:4X3B|rcsb pdb:4XAD|rcsb pdb:4XEN|rcsb pdb:4XJB|rcsb pdb:4XJD|rcsb pdb:4XJF|rcsb pdb:4XJG|rcsb pdb:4XJH|rcsb pdb:4XJI|rcsb pdb:4XN6|rcsb pdb:4XYY|rcsb pdb:4YEM|rcsb pdb:4YEN|rcsb pdb:4YEO|rcsb pdb:4YM8|rcsb pdb:4YOP|rcsb pdb:4Z3M|rcsb pdb:4Z41|rcsb pdb:4Z46|rcsb pdb:4Z98|rcsb pdb:4ZEE|rcsb pdb:4ZFP|rcsb pdb:4ZIX|rcsb pdb:5C6L|rcsb pdb:5D5C|rcsb pdb:5D5F|rcsb pdb:5A3E|rcsb pdb:5DL9|rcsb pdb:5DLA|rcsb pdb:5A3Z|rcsb pdb:5AMY|rcsb pdb:5APC|rcsb pdb:5APD|rcsb pdb:5APE|rcsb pdb:5DM9|rcsb pdb:5E4P|rcsb pdb:5E9R|rcsb pdb:5EBH|rcsb pdb:5F14|rcsb pdb:5F16|rcsb pdb:5F81|rcsb pdb:5F9U|rcsb pdb:5F9X|rcsb pdb:5APF|rcsb pdb:5B05|rcsb pdb:5B06|rcsb pdb:5B07|rcsb pdb:5B1F|rcsb pdb:5B1G|rcsb pdb:5B59|rcsb pdb:5FCP|rcsb pdb:5FDJ|rcsb pdb:5FEK|rcsb pdb:5FEL|rcsb pdb:5FHW|rcsb pdb:5FST|rcsb pdb:5GWB|rcsb pdb:5HLL|rcsb pdb:5HMJ|rcsb pdb:5HMV|rcsb pdb:5HNC|rcsb pdb:5HNL|rcsb pdb:5HQ1|rcsb pdb:5I4W|rcsb pdb:5I4X|rcsb pdb:5I4Y|rcsb pdb:5I53|rcsb pdb:5I54|rcsb pdb:5I5Q|rcsb pdb:5IDD|rcsb pdb:5IEL|rcsb pdb:5IHG|rcsb pdb:5II3|rcsb pdb:5ILC|rcsb pdb:5ILF|rcsb pdb:5J7C|rcsb pdb:5B5J|rcsb pdb:5C6I|rcsb pdb:5C6J|rcsb pdb:5JEN|rcsb pdb:5K2K|rcsb pdb:5K2N|rcsb pdb:6SIK|rcsb pdb:5NJP|rcsb pdb:5NJQ|rcsb pdb:5NJR|rcsb pdb:5NJS|rcsb pdb:5O4W|rcsb pdb:5O4X|rcsb pdb:5O6Q|rcsb pdb:5OB6|rcsb pdb:5OB7|rcsb pdb:5OB8|rcsb pdb:5OB9|rcsb pdb:5OCV|rcsb pdb:5OER|rcsb pdb:5OLE|rcsb pdb:5NJM|rcsb pdb:5OOV|rcsb pdb:5OOY|rcsb pdb:5OP1|rcsb pdb:5T3F|rcsb pdb:5TK0|rcsb pdb:5UVJ|rcsb pdb:5V4G|rcsb pdb:5V4H|rcsb pdb:5V4I|rcsb pdb:5WR9|rcsb pdb:5WRA|rcsb pdb:5WRB|rcsb pdb:5YIN|rcsb pdb:5YKY|rcsb pdb:6A10|rcsb pdb:6A4N|rcsb pdb:6A4O|rcsb pdb:6A4P|rcsb pdb:6A4Q|rcsb pdb:6ABN|rcsb pdb:6ABZ|rcsb pdb:6AC2|rcsb pdb:6AD5|rcsb pdb:6ADF|rcsb pdb:6AEA|rcsb pdb:6AGN|rcsb pdb:6AGR|rcsb pdb:6AHH|rcsb pdb:6AHL|rcsb pdb:6APM|rcsb pdb:6B7U|rcsb pdb:6B7V|rcsb pdb:6B7W|rcsb pdb:6BO1|rcsb pdb:6BO2|rcsb pdb:6BRE|rcsb pdb:6CIW|rcsb pdb:6D6E|rcsb pdb:6D6F|rcsb pdb:6D6G|rcsb pdb:6D6H|rcsb pdb:6F1L|rcsb pdb:6F1M|rcsb pdb:6F1O|rcsb pdb:6F1P|rcsb pdb:6F1R|rcsb pdb:6F2I|rcsb pdb:6F2J|rcsb pdb:6F2K|rcsb pdb:6F9X|rcsb pdb:6F9Y|rcsb pdb:6F9Z|rcsb pdb:6FA0|rcsb pdb:5K2P|rcsb pdb:5K2Q|rcsb pdb:5K2R|rcsb pdb:5K2S|rcsb pdb:5K7O|rcsb pdb:5KJ9|rcsb pdb:5KKI|rcsb pdb:5KKJ|rcsb pdb:5KXK|rcsb pdb:5KXL|rcsb pdb:5KXM|rcsb pdb:5KXN|rcsb pdb:5KXO|rcsb pdb:5KXP|rcsb pdb:5KXR|rcsb pdb:5KXS|rcsb pdb:5KXT|rcsb pdb:5KXW|rcsb pdb:5KXX|rcsb pdb:5KXY|rcsb pdb:5KXZ|rcsb pdb:5KY1|rcsb pdb:5L3H|rcsb pdb:5L3I|rcsb pdb:5L9J|rcsb pdb:5LA5|rcsb pdb:6FRO|rcsb pdb:5LA8|rcsb pdb:5LAF|rcsb pdb:5LAG|rcsb pdb:5LAN|rcsb pdb:5LIN|rcsb pdb:5LIO|rcsb pdb:5LVG|rcsb pdb:5LVH|rcsb pdb:5LVI|rcsb pdb:5LVJ|rcsb pdb:5LXW|rcsb pdb:5LYM|rcsb pdb:5LYT|rcsb pdb:5LYZ|rcsb pdb:5M1Y|rcsb pdb:5MJJ|rcsb pdb:5MYY|rcsb pdb:5NBJ|rcsb pdb:5NE0|rcsb pdb:5NJ1|rcsb pdb:6FRQ|rcsb pdb:6FSJ|rcsb pdb:6FTR|rcsb pdb:6G5C|rcsb pdb:6G5V|rcsb pdb:6G5Y|rcsb pdb:6G8A|rcsb pdb:6GF0|rcsb pdb:6GNL|rcsb pdb:6GOB|rcsb pdb:6GOH|rcsb pdb:6GOI|rcsb pdb:6GOJ|rcsb pdb:6H0K|rcsb pdb:6H0L|rcsb pdb:6H3B|rcsb pdb:6H79|rcsb pdb:6HT2|rcsb pdb:6HU5|rcsb pdb:6HY4|rcsb pdb:6HY6|rcsb pdb:6HY8|rcsb pdb:6HYB|rcsb pdb:6IG6|rcsb pdb:6IRJ|rcsb pdb:6JB2|rcsb pdb:6JB5|rcsb pdb:6JB8|rcsb pdb:6JXP|rcsb pdb:6JXQ|rcsb pdb:6JZI|rcsb pdb:6K5Q|rcsb pdb:6K8G|rcsb pdb:6KCB|rcsb pdb:6KCD|rcsb pdb:6KD1|rcsb pdb:6LAV|rcsb pdb:6LL3|rcsb pdb:6LT5|rcsb pdb:6LYT|rcsb pdb:6LYZ|rcsb pdb:6MQV|rcsb pdb:6MUZ|rcsb pdb:6MX9|rcsb pdb:6O2H|rcsb pdb:6P4A|rcsb pdb:6P4B|rcsb pdb:6P4D|rcsb pdb:6PBB|rcsb pdb:6PL9|rcsb pdb:6PLA|rcsb pdb:6PLB|rcsb pdb:6Q88|rcsb pdb:6Q8R|rcsb pdb:6Q8T|rcsb pdb:6QEA|rcsb pdb:6QNB|rcsb pdb:6QQ3|rcsb pdb:6QQC|rcsb pdb:6QQD|rcsb pdb:6QQE|rcsb pdb:6QQF|rcsb pdb:6QWW|rcsb pdb:6QWX|rcsb pdb:6QWY|rcsb pdb:6QWZ|rcsb pdb:6QX0|rcsb pdb:6QXW|rcsb pdb:6QXX|rcsb pdb:6QXY|rcsb pdb:6QY0|rcsb pdb:6QY1|rcsb pdb:6QY2|rcsb pdb:6QY4|rcsb pdb:6QY5|rcsb pdb:6RNB|rcsb pdb:6RNC|rcsb pdb:6RO3|rcsb pdb:6RO5|rcsb pdb:6RT1|rcsb pdb:6RT3|rcsb pdb:6RT9|rcsb pdb:6RTA|rcsb pdb:6RXI|rcsb pdb:6S2N|rcsb pdb:6S7N|rcsb pdb:6SET|rcsb pdb:6SEU|rcsb pdb:6SEW|rcsb pdb:6SEX|rcsb pdb:6SEZ|rcsb pdb:6SIJ|rcsb pdb:6SIL|rcsb pdb:6SIM|rcsb pdb:6SR0|rcsb pdb:6SR1|rcsb pdb:6SR2|rcsb pdb:6SR3|rcsb pdb:6SR4|rcsb pdb:6SR5|rcsb pdb:6SYC|rcsb pdb:6SYD|rcsb pdb:6SYE|rcsb pdb:6TVL|rcsb pdb:6TVY|rcsb pdb:6W7P|rcsb pdb:6W8E|rcsb pdb:6WRL|rcsb pdb:6WRM|rcsb pdb:6WX5|rcsb pdb:6YBF|rcsb pdb:6YBI|rcsb pdb:6YJX|rcsb pdb:6YOB|rcsb pdb:6YOC|rcsb pdb:6YOD|rcsb pdb:6YOE|rcsb pdb:6ZS8|rcsb pdb:7A70|rcsb pdb:7BE2|rcsb pdb:7BEB|rcsb pdb:7BEC|rcsb pdb:7BR5|rcsb pdb:7BVM|rcsb pdb:7BVO|rcsb pdb:7BYO|rcsb pdb:7BYP|rcsb pdb:7C09|rcsb pdb:7AVE|rcsb pdb:7AVF|rcsb pdb:7AVG|rcsb pdb:7BDZ|rcsb pdb:7BE0|rcsb pdb:7BE1|rcsb pdb:7CDK|rcsb pdb:7CDM|rcsb pdb:7CDN|rcsb pdb:7CDO|rcsb pdb:7CDP|rcsb pdb:7CDQ|rcsb pdb:7CDR|rcsb pdb:7CDS|rcsb pdb:7CDT|rcsb pdb:7CDU|rcsb pdb:7CJZ|rcsb pdb:7DEQ|rcsb pdb:7DER|rcsb pdb:7DTB|rcsb pdb:7DTF|rcsb pdb:7E02|rcsb pdb:7JMU|rcsb pdb:7KH5|rcsb pdb:7L84|rcsb pdb:7LYZ|rcsb pdb:7NJF|rcsb pdb:7NKF|rcsb pdb:8LYZ|rcsb pdb:9LYZ|reactome:R-GGA-6798695|reactome:R-GGA-6803157|rcsb pdb:7CVJ|rcsb pdb:7CVL|rcsb pdb:7D01|rcsb pdb:7D02|rcsb pdb:7D04|rcsb pdb:7D05|rcsb pdb:7D0W|refseq:NP_990612.1|dip:DIP-46258N|mint:MINT-8413726(identity) rcsb pdb:1BGI|rcsb pdb:1BHZ|rcsb pdb:1BVK|rcsb pdb:1BVX|rcsb pdb:1BWH|rcsb pdb:1BWI|rcsb pdb:1BWJ|rcsb pdb:1C08|rcsb pdb:1C10|rcsb pdb:1DPW|rcsb pdb:1DPX|rcsb pdb:1DQJ|rcsb pdb:1E8L|rcsb pdb:1F0W|rcsb pdb:1F10|rcsb pdb:1F3J|rcsb pdb:1FDL|rcsb pdb:1FLQ|rcsb pdb:1FLU|rcsb pdb:1FLW|rcsb pdb:1FLY|rcsb pdb:1FN5|rcsb pdb:1G7H|rcsb pdb:1G7I|rcsb pdb:1B2K|rcsb pdb:1G7J|rcsb pdb:1G7L|rcsb pdb:1G7M|rcsb pdb:1GPQ|rcsb pdb:1GWD|rcsb pdb:1GXV|rcsb pdb:1GXX|rcsb pdb:1H6M|rcsb pdb:1JIY|rcsb pdb:1JJ0|rcsb pdb:1JJ1|rcsb pdb:1JJ3|rcsb pdb:1JPO|rcsb pdb:1JTO|rcsb pdb:1JTT|rcsb pdb:1KIP|rcsb pdb:1KIQ|rcsb pdb:1KIR|rcsb pdb:1KXW|rcsb pdb:1KXX|rcsb pdb:1KXY|rcsb pdb:1LCN|rcsb pdb:1LJ3|rcsb pdb:1JIT|rcsb pdb:1LJ4|rcsb pdb:1LJE|rcsb pdb:1LJF|rcsb pdb:1LJG|rcsb pdb:1LJH|rcsb pdb:1LJI|rcsb pdb:1LJJ|rcsb pdb:1LJK|rcsb pdb:1LKR|rcsb pdb:1HC0|rcsb pdb:1HEL|rcsb pdb:1HEM|rcsb pdb:1HEN|rcsb pdb:1HEO|rcsb pdb:1HEP|rcsb pdb:1HEQ|rcsb pdb:1HER|rcsb pdb:1HEW|rcsb pdb:1HF4|rcsb pdb:1HSW|rcsb pdb:1HSX|rcsb pdb:1IC4|rcsb pdb:1IC5|rcsb pdb:1IC7|rcsb pdb:1IEE|rcsb pdb:1IO5|rcsb pdb:1IOQ|rcsb pdb:1IOR|rcsb pdb:1IOS|rcsb pdb:1IOT|rcsb pdb:1IR7|rcsb pdb:1IR8|rcsb pdb:1IR9|rcsb pdb:1J1O|rcsb pdb:1J1P|rcsb pdb:1J1X|rcsb pdb:1JA2|rcsb pdb:1H87|rcsb pdb:1JA4|rcsb pdb:1JA6|rcsb pdb:1JA7|rcsb pdb:1JIS|ensembl:ENSGALT00000016196(transcript)|go:"GO:0003796"(lysozyme activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016231"(beta-N-acetylglucosaminidase activity)|go:"GO:0016998"(cell wall macromolecule catabolic process)|ensembl:ENSGALG00000009963(gene)|go:"GO:0019835"(cytolysis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051672"(obsolete catabolism by organism of cell wall peptidoglycan in other organism)|interpro:IPR000974(Glycoside hydrolase, family 22, lysozyme)|interpro:IPR001916(Glycoside hydrolase, family 22)|interpro:IPR019799|interpro:IPR023346|interpro:IPR030056|rcsb pdb:132L|rcsb pdb:193L|rcsb pdb:194L|rcsb pdb:1A2Y|rcsb pdb:1AKI|rcsb pdb:1AT5|rcsb pdb:1AT6|rcsb pdb:1AZF|rcsb pdb:1B0D|rcsb pdb:1UIF|rcsb pdb:1UIG|rcsb pdb:1UIH|rcsb pdb:1UUZ|rcsb pdb:1V7S|rcsb pdb:1V7T|rcsb pdb:1VAT|rcsb pdb:1VAU|rcsb pdb:1UIE|rcsb pdb:1VDP|rcsb pdb:1VDQ|rcsb pdb:1VDS|rcsb pdb:1VDT|rcsb pdb:1VED|rcsb pdb:1VFB|rcsb pdb:1W6Z|rcsb pdb:1WTM|rcsb pdb:1WTN|rcsb pdb:1XEI|rcsb pdb:1XEJ|rcsb pdb:1XEK|rcsb pdb:1XFP|rcsb pdb:1XGP|rcsb pdb:1XGQ|rcsb pdb:1XGR|rcsb pdb:1XGT|rcsb pdb:1XGU|rcsb pdb:1YIK|rcsb pdb:1YIL|rcsb pdb:1YKX|rcsb pdb:1YKY|rcsb pdb:1YKZ|rcsb pdb:1LMA|rcsb pdb:1LPI|rcsb pdb:1LSA|rcsb pdb:1LSB|rcsb pdb:1LSC|rcsb pdb:1LSD|rcsb pdb:1LSE|rcsb pdb:1LSF|rcsb pdb:1LSG|rcsb pdb:1LSM|rcsb pdb:1LSN|rcsb pdb:1LSY|rcsb pdb:1LSZ|rcsb pdb:1LYO|rcsb pdb:1LYS|rcsb pdb:1LYZ|rcsb pdb:1LZ8|rcsb pdb:1LKS|rcsb pdb:1LZ9|rcsb pdb:1LZA|rcsb pdb:1LZB|rcsb pdb:1LZC|rcsb pdb:1LZD|rcsb pdb:1UA6|rcsb pdb:1UC0|rcsb pdb:1UCO|rcsb pdb:1UIA|rcsb pdb:1UIB|rcsb pdb:1UIC|rcsb pdb:1LZE|rcsb pdb:1LZG|rcsb pdb:1LZH|rcsb pdb:1LZN|rcsb pdb:1LZT|rcsb pdb:1MEL|rcsb pdb:1MLC|rcsb pdb:1N4F|rcsb pdb:1NBY|rcsb pdb:1NBZ|rcsb pdb:1NDG|rcsb pdb:1NDM|rcsb pdb:1P2C|rcsb pdb:1PS5|rcsb pdb:1QIO|rcsb pdb:1QTK|rcsb pdb:1RCM|rcsb pdb:1RFP|rcsb pdb:1RI8|rcsb pdb:1RJC|rcsb pdb:1SF4|rcsb pdb:1SF6|rcsb pdb:1SF7|rcsb pdb:1SFB|rcsb pdb:1SFG|rcsb pdb:1SQ2|rcsb pdb:1T3P|rcsb pdb:1T6V|rcsb pdb:1UID|rcsb pdb:1YL1|rcsb pdb:1YQV|rcsb pdb:1Z55|rcsb pdb:1ZMY|rcsb pdb:1ZV5|rcsb pdb:1ZVH|rcsb pdb:1ZVY|rcsb pdb:2A6U|rcsb pdb:2A7D|rcsb pdb:2A7F|rcsb pdb:2AUB|rcsb pdb:2B5Z|rcsb pdb:2BLX|rcsb pdb:2BLY|rcsb pdb:2BPU|rcsb pdb:2C8O|rcsb pdb:2C8P|rcsb pdb:2CDS|rcsb pdb:2CGI|rcsb pdb:2D4I|rcsb pdb:1YL0|rcsb pdb:2D4J|rcsb pdb:2D4K|rcsb pdb:2D6B|rcsb pdb:2D91|rcsb pdb:2DQD|rcsb pdb:2DQE|rcsb pdb:2DQC|rcsb pdb:2DQF|rcsb pdb:2DQG|rcsb pdb:2DQH|rcsb pdb:2DQI|rcsb pdb:2DQJ|rcsb pdb:2EIZ|rcsb pdb:2EKS|rcsb pdb:2EPE|rcsb pdb:2F2N|rcsb pdb:2F30|rcsb pdb:2F4A|rcsb pdb:2F4G|rcsb pdb:2FBB|rcsb pdb:2G4P|rcsb pdb:2G4Q|rcsb pdb:2H9J|rcsb pdb:2H9K|rcsb pdb:2HFM|rcsb pdb:2HS7|rcsb pdb:2HS9|rcsb pdb:2HSO|rcsb pdb:2HTX|rcsb pdb:2HU1|rcsb pdb:2HU3|rcsb pdb:2HUB|rcsb pdb:2I25|rcsb pdb:2I26|rcsb pdb:2I6Z|rcsb pdb:2IFF|rcsb pdb:2LYM|rcsb pdb:2LYO|rcsb pdb:2LYZ|rcsb pdb:2LZH|rcsb pdb:2LZT|rcsb pdb:2PC2|rcsb pdb:2Q0M|rcsb pdb:2VB1|rcsb pdb:2W1L|rcsb pdb:2W1M|rcsb pdb:2W1X|rcsb pdb:2W1Y|rcsb pdb:2WAR|rcsb pdb:2X0A|rcsb pdb:2XBR|rcsb pdb:2XBS|rcsb pdb:2XJW|rcsb pdb:2XTH|rcsb pdb:2YBH|rcsb pdb:2YBI|rcsb pdb:2YBJ|rcsb pdb:2YBL|rcsb pdb:2YBM|rcsb pdb:2YDG|rcsb pdb:2YSS|rcsb pdb:2YVB|rcsb pdb:2Z12|rcsb pdb:2Z18|rcsb pdb:2Z19|rcsb pdb:2ZNW|rcsb pdb:2YBN|rcsb pdb:2ZNX|rcsb pdb:2ZQ3|rcsb pdb:2ZYP|rcsb pdb:3A34|rcsb pdb:3A3Q|rcsb pdb:3A3R|rcsb pdb:3A67|rcsb pdb:3A6B|rcsb pdb:3A6C|rcsb pdb:3A8Z|rcsb pdb:3A90|rcsb pdb:3A91|rcsb pdb:3A92|rcsb pdb:3A93|rcsb pdb:3A94|rcsb pdb:3A95|rcsb pdb:3A96|rcsb pdb:3AGG|rcsb pdb:3AGH|rcsb pdb:3AGI|rcsb pdb:3AJN|rcsb pdb:3ATN|rcsb pdb:3ATO|rcsb pdb:3AW6|rcsb pdb:3AW7|rcsb pdb:3AZ4|rcsb pdb:3AZ5|rcsb pdb:3AZ6|rcsb pdb:3AZ7|rcsb pdb:3B6L|rcsb pdb:3B72|rcsb pdb:3D9A|rcsb pdb:3E3D|rcsb pdb:3EMS|rcsb pdb:3EXD|rcsb pdb:3F6Z|rcsb pdb:3G3A|rcsb pdb:3G3B|rcsb pdb:3HFM|rcsb pdb:3IJU|rcsb pdb:2ZQ4|rcsb pdb:3IJV|rcsb pdb:3J4G|rcsb pdb:3J6K|rcsb pdb:3KAM|rcsb pdb:3LYT|rcsb pdb:3LYZ|rcsb pdb:3LZT|rcsb pdb:3M18|rcsb pdb:3M3U|rcsb pdb:3MBE|rcsb pdb:3N9A|rcsb pdb:3N9C|rcsb pdb:3N9E|rcsb pdb:3OJP|rcsb pdb:3OK0|rcsb pdb:3OTP|rcsb pdb:3P4Z|rcsb pdb:3P64|rcsb pdb:3P65|rcsb pdb:3P66|rcsb pdb:3P68|rcsb pdb:3QE8|rcsb pdb:3QNG|rcsb pdb:3QY4|rcsb pdb:3LYO|rcsb pdb:3RNX|rcsb pdb:3RT5|rcsb pdb:3LYM|rcsb pdb:3WU7|rcsb pdb:3WU8|rcsb pdb:3WU9|rcsb pdb:4B49|rcsb pdb:3WUA|rcsb pdb:3WUL|rcsb pdb:3WUM|rcsb pdb:3WUN|rcsb pdb:4B4E|rcsb pdb:3WVX|rcsb pdb:3WVY|rcsb pdb:3WW5|rcsb pdb:3WW6|rcsb pdb:3WXT|rcsb pdb:3WXU|rcsb pdb:3ZEK|rcsb pdb:3ZVQ|rcsb pdb:4A7D|rcsb pdb:4A8A|rcsb pdb:4A8B|rcsb pdb:4AGA|rcsb pdb:4AXT|rcsb pdb:4B0D|rcsb pdb:4B1A|rcsb pdb:3RW8|rcsb pdb:3RZ4|rcsb pdb:3SP3|rcsb pdb:3T6U|rcsb pdb:3TMU|rcsb pdb:3TMV|rcsb pdb:3TMW|rcsb pdb:3TMX|rcsb pdb:3TXB|rcsb pdb:3TXD|rcsb pdb:3TXE|rcsb pdb:3TXF|rcsb pdb:3TXG|rcsb pdb:3TXH|rcsb pdb:3TXI|rcsb pdb:3TXJ|rcsb pdb:3TXK|rcsb pdb:3ULR|rcsb pdb:3W6A|rcsb pdb:3WL2|rcsb pdb:3WMK|rcsb pdb:3RU5|rcsb pdb:3WPJ|rcsb pdb:3WPK|rcsb pdb:3WPL|rcsb pdb:4DDC|rcsb pdb:4DT3|rcsb pdb:4E3U|rcsb pdb:4BAD|rcsb pdb:4BAF|rcsb pdb:4BAP|rcsb pdb:4BS7|rcsb pdb:4C3W|rcsb pdb:4CJ2|rcsb pdb:4D9Z|rcsb pdb:4DC4|rcsb pdb:4DD0|rcsb pdb:4DD1|rcsb pdb:4DD2|rcsb pdb:4DD3|rcsb pdb:4DD7|rcsb pdb:4DD9|rcsb pdb:4DDA|rcsb pdb:4DDB|rcsb pdb:4EOF|rcsb pdb:4B4I|rcsb pdb:4B4J|rcsb pdb:4FJR|rcsb pdb:4G49|rcsb pdb:4G4B|rcsb pdb:4G4C|rcsb pdb:4G4H|rcsb pdb:4GCB|rcsb pdb:4GCC|rcsb pdb:4GCD|rcsb pdb:4GCE|rcsb pdb:4GCF|rcsb pdb:4GLA|rcsb pdb:4GLV|rcsb pdb:4GN3|rcsb pdb:4GN4|rcsb pdb:4GN5|rcsb pdb:4H1P|rcsb pdb:4H8X|rcsb pdb:4H8Y|rcsb pdb:4H8Z|rcsb pdb:4H90|rcsb pdb:4H91|rcsb pdb:4ETE|rcsb pdb:4H92|rcsb pdb:4H93|rcsb pdb:4H94|rcsb pdb:4H9A|rcsb pdb:4ET9|rcsb pdb:4ETA|rcsb pdb:4ETB|rcsb pdb:4ETC|rcsb pdb:4ETD|rcsb pdb:4ET8|rcsb pdb:4H9B|rcsb pdb:4H9C|rcsb pdb:4H9E|rcsb pdb:4H9F|rcsb pdb:4H9H|rcsb pdb:4H9I|rcsb pdb:4HP0|rcsb pdb:4HPI|rcsb pdb:4HSF|rcsb pdb:4HTK|rcsb pdb:4HTN|rcsb pdb:4HTQ|rcsb pdb:4HV1|rcsb pdb:4HV2|rcsb pdb:4I8S|rcsb pdb:4IAS|rcsb pdb:4IAT|rcsb pdb:4II8|rcsb pdb:4J1A|rcsb pdb:4J1B|rcsb pdb:4J7V|rcsb pdb:4KXI|rcsb pdb:4LFP|rcsb pdb:4PPO|rcsb pdb:4LFX|rcsb pdb:4LGK|rcsb pdb:4LT0|rcsb pdb:4LT1|rcsb pdb:4LT2|rcsb pdb:4LT3|rcsb pdb:4LYB|rcsb pdb:4LYC|rcsb pdb:4LYM|rcsb pdb:4LYO|rcsb pdb:4LYT|rcsb pdb:4LYZ|rcsb pdb:4LZT|rcsb pdb:4M4O|rcsb pdb:4M6D|rcsb pdb:4MR1|rcsb pdb:4N0J|rcsb pdb:4N1C|rcsb pdb:4N1E|rcsb pdb:4N5R|rcsb pdb:4N8Z|rcsb pdb:4N9R|rcsb pdb:4NEB|rcsb pdb:4NFV|rcsb pdb:4NG1|rcsb pdb:4NG8|rcsb pdb:4NGI|rcsb pdb:4NGJ|rcsb pdb:4NGL|rcsb pdb:4NGO|rcsb pdb:4NGV|rcsb pdb:4NGW|rcsb pdb:4NGY|rcsb pdb:4NGZ|rcsb pdb:4NHI|rcsb pdb:4NHP|rcsb pdb:4NHQ|rcsb pdb:4NHS|rcsb pdb:4NHT|rcsb pdb:4NGK|rcsb pdb:4NIJ|rcsb pdb:4NSG|rcsb pdb:4NSH|rcsb pdb:4NSI|rcsb pdb:4NSJ|rcsb pdb:4NWE|rcsb pdb:4NWH|rcsb pdb:4NY5|rcsb pdb:4O34|rcsb pdb:4OOO|rcsb pdb:4OOT|rcsb pdb:4OWA|rcsb pdb:4OWB|rcsb pdb:4OWC|rcsb pdb:4OWE|rcsb pdb:4OWH|rcsb pdb:4P2E|rcsb pdb:4PGJ|rcsb pdb:4PHI|rcsb pdb:4WG7|rcsb pdb:4WL6|rcsb pdb:4WL7|rcsb pdb:4WLD|rcsb pdb:4WLT|rcsb pdb:4WLX|rcsb pdb:4WLY|rcsb pdb:4WM1|rcsb pdb:4WM2|rcsb pdb:4WM3|rcsb pdb:4WM4|rcsb pdb:4WM5|rcsb pdb:4WM6|rcsb pdb:4PRU|rcsb pdb:4QEQ|rcsb pdb:4QGZ|rcsb pdb:4QY9|rcsb pdb:4R0F|rcsb pdb:4R6C|rcsb pdb:4RDS|rcsb pdb:4RLM|rcsb pdb:4RLN|rcsb pdb:4RW1|rcsb pdb:4RW2|rcsb pdb:4TSA|rcsb pdb:4TSB|rcsb pdb:4TSC|rcsb pdb:4TTD|rcsb pdb:4PRQ|rcsb pdb:4TUN|rcsb pdb:4TWS|rcsb pdb:4U3X|rcsb pdb:4UWN|rcsb pdb:4UWU|rcsb pdb:4UWV|rcsb pdb:4W94|rcsb pdb:4W96|rcsb pdb:4WG1|rcsb pdb:4WMG|rcsb pdb:4WO6|rcsb pdb:4WO9|rcsb pdb:4WOA|rcsb pdb:4X3B|rcsb pdb:4XAD|rcsb pdb:4XEN|rcsb pdb:4XJB|rcsb pdb:4XJD|rcsb pdb:4XJF|rcsb pdb:4XJG|rcsb pdb:4XJH|rcsb pdb:4XJI|rcsb pdb:4XN6|rcsb pdb:4XYY|rcsb pdb:4YEM|rcsb pdb:4YEN|rcsb pdb:4YEO|rcsb pdb:4YM8|rcsb pdb:4YOP|rcsb pdb:4Z3M|rcsb pdb:4Z41|rcsb pdb:4Z46|rcsb pdb:4Z98|rcsb pdb:4ZEE|rcsb pdb:4ZFP|rcsb pdb:4ZIX|rcsb pdb:5C6L|rcsb pdb:5D5C|rcsb pdb:5D5F|rcsb pdb:5A3E|rcsb pdb:5DL9|rcsb pdb:5DLA|rcsb pdb:5A3Z|rcsb pdb:5AMY|rcsb pdb:5APC|rcsb pdb:5APD|rcsb pdb:5APE|rcsb pdb:5DM9|rcsb pdb:5E4P|rcsb pdb:5E9R|rcsb pdb:5EBH|rcsb pdb:5F14|rcsb pdb:5F16|rcsb pdb:5F81|rcsb pdb:5F9U|rcsb pdb:5F9X|rcsb pdb:5APF|rcsb pdb:5B05|rcsb pdb:5B06|rcsb pdb:5B07|rcsb pdb:5B1F|rcsb pdb:5B1G|rcsb pdb:5B59|rcsb pdb:5FCP|rcsb pdb:5FDJ|rcsb pdb:5FEK|rcsb pdb:5FEL|rcsb pdb:5FHW|rcsb pdb:5FST|rcsb pdb:5GWB|rcsb pdb:5HLL|rcsb pdb:5HMJ|rcsb pdb:5HMV|rcsb pdb:5HNC|rcsb pdb:5HNL|rcsb pdb:5HQ1|rcsb pdb:5I4W|rcsb pdb:5I4X|rcsb pdb:5I4Y|rcsb pdb:5I53|rcsb pdb:5I54|rcsb pdb:5I5Q|rcsb pdb:5IDD|rcsb pdb:5IEL|rcsb pdb:5IHG|rcsb pdb:5II3|rcsb pdb:5ILC|rcsb pdb:5ILF|rcsb pdb:5J7C|rcsb pdb:5B5J|rcsb pdb:5C6I|rcsb pdb:5C6J|rcsb pdb:5JEN|rcsb pdb:5K2K|rcsb pdb:5K2N|rcsb pdb:6SIK|rcsb pdb:5NJP|rcsb pdb:5NJQ|rcsb pdb:5NJR|rcsb pdb:5NJS|rcsb pdb:5O4W|rcsb pdb:5O4X|rcsb pdb:5O6Q|rcsb pdb:5OB6|rcsb pdb:5OB7|rcsb pdb:5OB8|rcsb pdb:5OB9|rcsb pdb:5OCV|rcsb pdb:5OER|rcsb pdb:5OLE|rcsb pdb:5NJM|rcsb pdb:5OOV|rcsb pdb:5OOY|rcsb pdb:5OP1|rcsb pdb:5T3F|rcsb pdb:5TK0|rcsb pdb:5UVJ|rcsb pdb:5V4G|rcsb pdb:5V4H|rcsb pdb:5V4I|rcsb pdb:5WR9|rcsb pdb:5WRA|rcsb pdb:5WRB|rcsb pdb:5YIN|rcsb pdb:5YKY|rcsb pdb:6A10|rcsb pdb:6A4N|rcsb pdb:6A4O|rcsb pdb:6A4P|rcsb pdb:6A4Q|rcsb pdb:6ABN|rcsb pdb:6ABZ|rcsb pdb:6AC2|rcsb pdb:6AD5|rcsb pdb:6ADF|rcsb pdb:6AEA|rcsb pdb:6AGN|rcsb pdb:6AGR|rcsb pdb:6AHH|rcsb pdb:6AHL|rcsb pdb:6APM|rcsb pdb:6B7U|rcsb pdb:6B7V|rcsb pdb:6B7W|rcsb pdb:6BO1|rcsb pdb:6BO2|rcsb pdb:6BRE|rcsb pdb:6CIW|rcsb pdb:6D6E|rcsb pdb:6D6F|rcsb pdb:6D6G|rcsb pdb:6D6H|rcsb pdb:6F1L|rcsb pdb:6F1M|rcsb pdb:6F1O|rcsb pdb:6F1P|rcsb pdb:6F1R|rcsb pdb:6F2I|rcsb pdb:6F2J|rcsb pdb:6F2K|rcsb pdb:6F9X|rcsb pdb:6F9Y|rcsb pdb:6F9Z|rcsb pdb:6FA0|rcsb pdb:5K2P|rcsb pdb:5K2Q|rcsb pdb:5K2R|rcsb pdb:5K2S|rcsb pdb:5K7O|rcsb pdb:5KJ9|rcsb pdb:5KKI|rcsb pdb:5KKJ|rcsb pdb:5KXK|rcsb pdb:5KXL|rcsb pdb:5KXM|rcsb pdb:5KXN|rcsb pdb:5KXO|rcsb pdb:5KXP|rcsb pdb:5KXR|rcsb pdb:5KXS|rcsb pdb:5KXT|rcsb pdb:5KXW|rcsb pdb:5KXX|rcsb pdb:5KXY|rcsb pdb:5KXZ|rcsb pdb:5KY1|rcsb pdb:5L3H|rcsb pdb:5L3I|rcsb pdb:5L9J|rcsb pdb:5LA5|rcsb pdb:6FRO|rcsb pdb:5LA8|rcsb pdb:5LAF|rcsb pdb:5LAG|rcsb pdb:5LAN|rcsb pdb:5LIN|rcsb pdb:5LIO|rcsb pdb:5LVG|rcsb pdb:5LVH|rcsb pdb:5LVI|rcsb pdb:5LVJ|rcsb pdb:5LXW|rcsb pdb:5LYM|rcsb pdb:5LYT|rcsb pdb:5LYZ|rcsb pdb:5M1Y|rcsb pdb:5MJJ|rcsb pdb:5MYY|rcsb pdb:5NBJ|rcsb pdb:5NE0|rcsb pdb:5NJ1|rcsb pdb:6FRQ|rcsb pdb:6FSJ|rcsb pdb:6FTR|rcsb pdb:6G5C|rcsb pdb:6G5V|rcsb pdb:6G5Y|rcsb pdb:6G8A|rcsb pdb:6GF0|rcsb pdb:6GNL|rcsb pdb:6GOB|rcsb pdb:6GOH|rcsb pdb:6GOI|rcsb pdb:6GOJ|rcsb pdb:6H0K|rcsb pdb:6H0L|rcsb pdb:6H3B|rcsb pdb:6H79|rcsb pdb:6HT2|rcsb pdb:6HU5|rcsb pdb:6HY4|rcsb pdb:6HY6|rcsb pdb:6HY8|rcsb pdb:6HYB|rcsb pdb:6IG6|rcsb pdb:6IRJ|rcsb pdb:6JB2|rcsb pdb:6JB5|rcsb pdb:6JB8|rcsb pdb:6JXP|rcsb pdb:6JXQ|rcsb pdb:6JZI|rcsb pdb:6K5Q|rcsb pdb:6K8G|rcsb pdb:6KCB|rcsb pdb:6KCD|rcsb pdb:6KD1|rcsb pdb:6LAV|rcsb pdb:6LL3|rcsb pdb:6LT5|rcsb pdb:6LYT|rcsb pdb:6LYZ|rcsb pdb:6MQV|rcsb pdb:6MUZ|rcsb pdb:6MX9|rcsb pdb:6O2H|rcsb pdb:6P4A|rcsb pdb:6P4B|rcsb pdb:6P4D|rcsb pdb:6PBB|rcsb pdb:6PL9|rcsb pdb:6PLA|rcsb pdb:6PLB|rcsb pdb:6Q88|rcsb pdb:6Q8R|rcsb pdb:6Q8T|rcsb pdb:6QEA|rcsb pdb:6QNB|rcsb pdb:6QQ3|rcsb pdb:6QQC|rcsb pdb:6QQD|rcsb pdb:6QQE|rcsb pdb:6QQF|rcsb pdb:6QWW|rcsb pdb:6QWX|rcsb pdb:6QWY|rcsb pdb:6QWZ|rcsb pdb:6QX0|rcsb pdb:6QXW|rcsb pdb:6QXX|rcsb pdb:6QXY|rcsb pdb:6QY0|rcsb pdb:6QY1|rcsb pdb:6QY2|rcsb pdb:6QY4|rcsb pdb:6QY5|rcsb pdb:6RNB|rcsb pdb:6RNC|rcsb pdb:6RO3|rcsb pdb:6RO5|rcsb pdb:6RT1|rcsb pdb:6RT3|rcsb pdb:6RT9|rcsb pdb:6RTA|rcsb pdb:6RXI|rcsb pdb:6S2N|rcsb pdb:6S7N|rcsb pdb:6SET|rcsb pdb:6SEU|rcsb pdb:6SEW|rcsb pdb:6SEX|rcsb pdb:6SEZ|rcsb pdb:6SIJ|rcsb pdb:6SIL|rcsb pdb:6SIM|rcsb pdb:6SR0|rcsb pdb:6SR1|rcsb pdb:6SR2|rcsb pdb:6SR3|rcsb pdb:6SR4|rcsb pdb:6SR5|rcsb pdb:6SYC|rcsb pdb:6SYD|rcsb pdb:6SYE|rcsb pdb:6TVL|rcsb pdb:6TVY|rcsb pdb:6W7P|rcsb pdb:6W8E|rcsb pdb:6WRL|rcsb pdb:6WRM|rcsb pdb:6WX5|rcsb pdb:6YBF|rcsb pdb:6YBI|rcsb pdb:6YJX|rcsb pdb:6YOB|rcsb pdb:6YOC|rcsb pdb:6YOD|rcsb pdb:6YOE|rcsb pdb:6ZS8|rcsb pdb:7A70|rcsb pdb:7BE2|rcsb pdb:7BEB|rcsb pdb:7BEC|rcsb pdb:7BR5|rcsb pdb:7BVM|rcsb pdb:7BVO|rcsb pdb:7BYO|rcsb pdb:7BYP|rcsb pdb:7C09|rcsb pdb:7AVE|rcsb pdb:7AVF|rcsb pdb:7AVG|rcsb pdb:7BDZ|rcsb pdb:7BE0|rcsb pdb:7BE1|rcsb pdb:7CDK|rcsb pdb:7CDM|rcsb pdb:7CDN|rcsb pdb:7CDO|rcsb pdb:7CDP|rcsb pdb:7CDQ|rcsb pdb:7CDR|rcsb pdb:7CDS|rcsb pdb:7CDT|rcsb pdb:7CDU|rcsb pdb:7CJZ|rcsb pdb:7DEQ|rcsb pdb:7DER|rcsb pdb:7DTB|rcsb pdb:7DTF|rcsb pdb:7E02|rcsb pdb:7JMU|rcsb pdb:7KH5|rcsb pdb:7L84|rcsb pdb:7LYZ|rcsb pdb:7NJF|rcsb pdb:7NKF|rcsb pdb:8LYZ|rcsb pdb:9LYZ|reactome:R-GGA-6798695|reactome:R-GGA-6803157|rcsb pdb:7CVJ|rcsb pdb:7CVL|rcsb pdb:7D01|rcsb pdb:7D02|rcsb pdb:7D04|rcsb pdb:7D05|rcsb pdb:7D0W|refseq:NP_990612.1|dip:DIP-46258N|mint:MINT-8413728(identity) - - - figure legend:f4b|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/06 2014/10/16 rogid:h5MqSdRIthgxU5zzOYEGbZmMvo89031 rogid:h5MqSdRIthgxU5zzOYEGbZmMvo89031 intact-crc:1D85AB5ED1BE3C02|rigid:ERUQG9grlkQm2hq2L8sKEtn392o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01315 uniprotkb:P01315 intact:EBI-8437944|intact:MINT-1505666|uniprotkb:Q9TSJ5|ensembl:ENSSSCP00000044635|ensembl:ENSSSCP00015002060|ensembl:ENSSSCP00025013482|ensembl:ENSSSCP00030047908|ensembl:ENSSSCP00035009642|ensembl:ENSSSCP00040009750|ensembl:ENSSSCP00045005838|ensembl:ENSSSCP00050004834|ensembl:ENSSSCP00055025559|ensembl:ENSSSCP00060020355|ensembl:ENSSSCP00065038365|ensembl:ENSSSCP00070024989 intact:EBI-8437944|intact:MINT-1505666|uniprotkb:Q9TSJ5|ensembl:ENSSSCP00000044635|ensembl:ENSSSCP00015002060|ensembl:ENSSSCP00025013482|ensembl:ENSSSCP00030047908|ensembl:ENSSSCP00035009642|ensembl:ENSSSCP00040009750|ensembl:ENSSSCP00045005838|ensembl:ENSSSCP00050004834|ensembl:ENSSSCP00055025559|ensembl:ENSSSCP00060020355|ensembl:ENSSSCP00065038365|ensembl:ENSSSCP00070024989 psi-mi:ins_pig(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:ins_pig(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:"MI:0872"(atomic force microscopy) Babenko et al. (2013) pubmed:23416304|mint:MINT-8413634|mint:d-12-02034r1 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8437998|mint:MINT-8413752 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001103242.1|ensembl:ENSSSCG00000033740(gene)|ensembl:ENSSSCG00015004005(gene)|ensembl:ENSSSCG00025023773(gene)|ensembl:ENSSSCG00030073948(gene)|ensembl:ENSSSCG00035019667(gene)|ensembl:ENSSSCG00040017207(gene)|ensembl:ENSSSCG00045005189(gene)|ensembl:ENSSSCG00050008342(gene)|ensembl:ENSSSCG00055016292(gene)|ensembl:ENSSSCG00060035069(gene)|ensembl:ENSSSCG00065063887(gene)|ensembl:ENSSSCG00070015252(gene)|ensembl:ENSSSCT00000064136(transcript)|ensembl:ENSSSCT00015005290(transcript)|ensembl:ENSSSCT00025032226(transcript)|ensembl:ENSSSCT00030103634(transcript)|ensembl:ENSSSCT00035025488(transcript)|ensembl:ENSSSCT00040023180(transcript)|ensembl:ENSSSCT00045008618(transcript)|ensembl:ENSSSCT00050011348(transcript)|ensembl:ENSSSCT00055032104(transcript)|ensembl:ENSSSCT00060047539(transcript)|ensembl:ENSSSCT00065087685(transcript)|ensembl:ENSSSCT00070029958(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002020"(protease binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006521"(regulation of cellular amino acid metabolic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0010750"(positive regulation of nitric oxide mediated signal transduction)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0038060"(nitric oxide-cGMP-mediated signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045818"(negative regulation of glycogen catabolic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046631"(alpha-beta T cell activation)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903576"(response to L-arginine)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000252"(negative regulation of feeding behavior)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|rcsb pdb:1B17|rcsb pdb:1B18|rcsb pdb:1B19|rcsb pdb:1B2A|rcsb pdb:1B2B|rcsb pdb:1B2C|rcsb pdb:1B2D|rcsb pdb:1B2E|rcsb pdb:1B2F|rcsb pdb:1B2G|rcsb pdb:1DEI|rcsb pdb:1IZA|rcsb pdb:1IZB|rcsb pdb:1M5A|rcsb pdb:1MPJ|rcsb pdb:1SDB|rcsb pdb:1WAV|rcsb pdb:1ZEI|rcsb pdb:1ZNI|rcsb pdb:2EFA|rcsb pdb:2G4M|rcsb pdb:2TCI|rcsb pdb:2ZPP|rcsb pdb:3FHP|rcsb pdb:3GKY|rcsb pdb:3INS|rcsb pdb:3MTH|rcsb pdb:3RTO|rcsb pdb:3T2A|rcsb pdb:4A7E|rcsb pdb:4INS|rcsb pdb:5D52|rcsb pdb:5D53|rcsb pdb:5D54|rcsb pdb:5D5E|rcsb pdb:5FB6|rcsb pdb:5LIS|rcsb pdb:6INS|rcsb pdb:6Z7Z|rcsb pdb:7INS|rcsb pdb:9INS|mint:MINT-8413754(identity) refseq:NP_001103242.1|ensembl:ENSSSCG00000033740(gene)|ensembl:ENSSSCG00015004005(gene)|ensembl:ENSSSCG00025023773(gene)|ensembl:ENSSSCG00030073948(gene)|ensembl:ENSSSCG00035019667(gene)|ensembl:ENSSSCG00040017207(gene)|ensembl:ENSSSCG00045005189(gene)|ensembl:ENSSSCG00050008342(gene)|ensembl:ENSSSCG00055016292(gene)|ensembl:ENSSSCG00060035069(gene)|ensembl:ENSSSCG00065063887(gene)|ensembl:ENSSSCG00070015252(gene)|ensembl:ENSSSCT00000064136(transcript)|ensembl:ENSSSCT00015005290(transcript)|ensembl:ENSSSCT00025032226(transcript)|ensembl:ENSSSCT00030103634(transcript)|ensembl:ENSSSCT00035025488(transcript)|ensembl:ENSSSCT00040023180(transcript)|ensembl:ENSSSCT00045008618(transcript)|ensembl:ENSSSCT00050011348(transcript)|ensembl:ENSSSCT00055032104(transcript)|ensembl:ENSSSCT00060047539(transcript)|ensembl:ENSSSCT00065087685(transcript)|ensembl:ENSSSCT00070029958(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002020"(protease binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006521"(regulation of cellular amino acid metabolic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0010750"(positive regulation of nitric oxide mediated signal transduction)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0038060"(nitric oxide-cGMP-mediated signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045818"(negative regulation of glycogen catabolic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046631"(alpha-beta T cell activation)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903576"(response to L-arginine)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000252"(negative regulation of feeding behavior)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|rcsb pdb:1B17|rcsb pdb:1B18|rcsb pdb:1B19|rcsb pdb:1B2A|rcsb pdb:1B2B|rcsb pdb:1B2C|rcsb pdb:1B2D|rcsb pdb:1B2E|rcsb pdb:1B2F|rcsb pdb:1B2G|rcsb pdb:1DEI|rcsb pdb:1IZA|rcsb pdb:1IZB|rcsb pdb:1M5A|rcsb pdb:1MPJ|rcsb pdb:1SDB|rcsb pdb:1WAV|rcsb pdb:1ZEI|rcsb pdb:1ZNI|rcsb pdb:2EFA|rcsb pdb:2G4M|rcsb pdb:2TCI|rcsb pdb:2ZPP|rcsb pdb:3FHP|rcsb pdb:3GKY|rcsb pdb:3INS|rcsb pdb:3MTH|rcsb pdb:3RTO|rcsb pdb:3T2A|rcsb pdb:4A7E|rcsb pdb:4INS|rcsb pdb:5D52|rcsb pdb:5D53|rcsb pdb:5D54|rcsb pdb:5D5E|rcsb pdb:5FB6|rcsb pdb:5LIS|rcsb pdb:6INS|rcsb pdb:6Z7Z|rcsb pdb:7INS|rcsb pdb:9INS|mint:MINT-8413756(identity) - function:Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver|comment:mint function:Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver|comment:mint figure legend:f4f|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/06 2014/10/16 rogid:jJtfIrm2VcLfHHHuPKRkLde+nW09823 rogid:jJtfIrm2VcLfHHHuPKRkLde+nW09823 intact-crc:CCA88FD88D3C4AAB|rigid:Kel3BPpjGvsKkiK0z6qwVwXWg4M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01308 uniprotkb:P01308 intact:EBI-7090529|ensembl:ENSP00000250971|ensembl:ENSP00000370731|ensembl:ENSP00000380432|uniprotkb:Q5EEX2|intact:MINT-106847 intact:EBI-7090529|ensembl:ENSP00000250971|ensembl:ENSP00000370731|ensembl:ENSP00000380432|uniprotkb:Q5EEX2|intact:MINT-106847 psi-mi:ins_human(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:ins_human(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:"MI:0872"(atomic force microscopy) Babenko et al. (2013) pubmed:23416304|mint:MINT-8413634|mint:d-12-02034r1 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8437891|mint:MINT-8413743 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278826.1|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006521"(regulation of cellular amino acid metabolic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010750"(positive regulation of nitric oxide mediated signal transduction)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030133"(transport vesicle)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031904"(endosome lumen)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038060"(nitric oxide-cGMP-mediated signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045818"(negative regulation of glycogen catabolic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046631"(alpha-beta T cell activation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050890"(cognition)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0005179"(hormone activity)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000252"(negative regulation of feeding behavior)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|mint:P01308|rcsb pdb:1A7F|rcsb pdb:1AI0|rcsb pdb:1AIY|rcsb pdb:1B9E|rcsb pdb:1BEN|rcsb pdb:1EFE|rcsb pdb:1EV3|rcsb pdb:1EV6|rcsb pdb:1EVR|rcsb pdb:1FU2|rcsb pdb:1FUB|rcsb pdb:1G7A|rcsb pdb:1G7B|rcsb pdb:1GUJ|rcsb pdb:1HIQ|rcsb pdb:1HIS|rcsb pdb:1HIT|rcsb pdb:1HLS|rcsb pdb:1HTV|rcsb pdb:1HUI|rcsb pdb:1IOG|rcsb pdb:1IOH|rcsb pdb:1J73|rcsb pdb:1JCA|rcsb pdb:1JCO|rcsb pdb:1JK8|rcsb pdb:1K3M|rcsb pdb:1KMF|rcsb pdb:1LKQ|rcsb pdb:1LPH|rcsb pdb:1MHI|rcsb pdb:1MHJ|rcsb pdb:1MSO|rcsb pdb:1OS3|rcsb pdb:1OS4|rcsb pdb:1Q4V|rcsb pdb:1QIY|rcsb pdb:1QIZ|rcsb pdb:1QJ0|rcsb pdb:1RWE|rcsb pdb:1SF1|rcsb pdb:1SJT|rcsb pdb:1SJU|rcsb pdb:1T0C|rcsb pdb:1T1K|rcsb pdb:1T1P|rcsb pdb:1T1Q|rcsb pdb:1TRZ|rcsb pdb:1TYL|rcsb pdb:1TYM|rcsb pdb:1UZ9|rcsb pdb:1VKT|rcsb pdb:1W8P|rcsb pdb:1XDA|rcsb pdb:1XGL|rcsb pdb:1XW7|rcsb pdb:1ZEG|rcsb pdb:1ZEH|rcsb pdb:1ZNJ|rcsb pdb:2AIY|rcsb pdb:2C8Q|rcsb pdb:2C8R|rcsb pdb:2CEU|rcsb pdb:2G54|rcsb pdb:2G56|rcsb pdb:2H67|rcsb pdb:2HH4|rcsb pdb:2HHO|rcsb pdb:2HIU|rcsb pdb:2JMN|rcsb pdb:2JUM|rcsb pdb:2JUU|rcsb pdb:2JUV|rcsb pdb:2JZQ|rcsb pdb:2K91|rcsb pdb:2K9R|rcsb pdb:2KJJ|rcsb pdb:2KJU|rcsb pdb:2JV1|rcsb pdb:2KQP|rcsb pdb:2KQQ|rcsb pdb:2KXK|rcsb pdb:2L1Y|rcsb pdb:2L1Z|rcsb pdb:2LGB|rcsb pdb:2LWZ|rcsb pdb:2M1D|rcsb pdb:2M1E|rcsb pdb:2M2M|rcsb pdb:2M2N|rcsb pdb:2M2O|rcsb pdb:2M2P|rcsb pdb:2MLI|rcsb pdb:2MPG|rcsb pdb:2MPI|rcsb pdb:2MVC|rcsb pdb:2MVD|rcsb pdb:2N2V|rcsb pdb:2N2W|rcsb pdb:2N2X|rcsb pdb:2OLY|rcsb pdb:2OLZ|rcsb pdb:2OM0|rcsb pdb:2OM1|rcsb pdb:2OMG|rcsb pdb:2OMH|rcsb pdb:2OMI|rcsb pdb:2OMQ|rcsb pdb:2QIU|rcsb pdb:2R34|rcsb pdb:2R35|rcsb pdb:2R36|rcsb pdb:2RN5|rcsb pdb:2VJZ|rcsb pdb:2VK0|rcsb pdb:2W44|rcsb pdb:2WBY|rcsb pdb:2WC0|rcsb pdb:2WRU|rcsb pdb:2WRV|rcsb pdb:2WRW|rcsb pdb:2WRX|rcsb pdb:2WS0|rcsb pdb:2WS1|rcsb pdb:2WS4|rcsb pdb:2WS6|rcsb pdb:2WS7|rcsb pdb:3AIY|rcsb pdb:3BXQ|rcsb pdb:3E7Y|rcsb pdb:3E7Z|rcsb pdb:3EXX|rcsb pdb:3FQ9|rcsb pdb:3HYD|rcsb pdb:3I3Z|rcsb pdb:3I40|rcsb pdb:3ILG|rcsb pdb:3INC|rcsb pdb:3IR0|rcsb pdb:3JSD|rcsb pdb:3KQ6|rcsb pdb:3P2X|rcsb pdb:3P33|rcsb pdb:3Q6E|rcsb pdb:3ROV|rcsb pdb:3TT8|rcsb pdb:3U4N|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V19|rcsb pdb:3V1G|rcsb pdb:3W11|rcsb pdb:3W12|rcsb pdb:3W13|rcsb pdb:3W7Y|rcsb pdb:3W7Z|rcsb pdb:3W80|rcsb pdb:3ZI3|rcsb pdb:3ZQR|rcsb pdb:3ZS2|rcsb pdb:3ZU1|rcsb pdb:4AIY|rcsb pdb:4AJX|rcsb pdb:4AJZ|rcsb pdb:4AK0|rcsb pdb:4AKJ|rcsb pdb:4CXL|rcsb pdb:4CXN|rcsb pdb:4CY7|rcsb pdb:4EFX|rcsb pdb:4EWW|rcsb pdb:4EWX|rcsb pdb:4EWZ|rcsb pdb:4EX0|rcsb pdb:4EX1|rcsb pdb:4EXX|rcsb pdb:4EY1|rcsb pdb:4EY9|rcsb pdb:4EYD|rcsb pdb:4EYN|rcsb pdb:4EYP|rcsb pdb:4F0N|rcsb pdb:4F0O|rcsb pdb:4F1A|rcsb pdb:4F1B|rcsb pdb:4F1C|rcsb pdb:4F1D|rcsb pdb:4F1F|rcsb pdb:4F1G|rcsb pdb:4F4T|rcsb pdb:4F4V|rcsb pdb:4F51|rcsb pdb:4F8F|rcsb pdb:4FG3|rcsb pdb:4FKA|rcsb pdb:4GBC|rcsb pdb:4GBI|rcsb pdb:4GBK|rcsb pdb:4GBL|rcsb pdb:4GBN|rcsb pdb:4IUZ|rcsb pdb:4IYD|rcsb pdb:4IYF|rcsb pdb:4NIB|rcsb pdb:4OGA|rcsb pdb:4P65|rcsb pdb:4RXW|rcsb pdb:4UNE|rcsb pdb:4UNG|rcsb pdb:4UNH|rcsb pdb:4WDI|rcsb pdb:4XC4|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5AIY|rcsb pdb:5BOQ|rcsb pdb:5BPO|rcsb pdb:5BQQ|rcsb pdb:5BTS|rcsb pdb:5C0D|rcsb pdb:5CJO|rcsb pdb:5CNY|rcsb pdb:5CO2|rcsb pdb:5CO6|rcsb pdb:5CO9|rcsb pdb:5E7W|rcsb pdb:5EMS|rcsb pdb:5EN9|rcsb pdb:5ENA|rcsb pdb:5HPR|rcsb pdb:5HPU|rcsb pdb:5HQI|rcsb pdb:5HRQ|rcsb pdb:5HYJ|rcsb pdb:5MAM|rcsb pdb:5MHD|rcsb pdb:5MT3|rcsb pdb:5MT9|rcsb pdb:5MWQ|rcsb pdb:5T7R|rcsb pdb:5UDP|rcsb pdb:5UOZ|rcsb pdb:5UQA|rcsb pdb:5URT|rcsb pdb:5URU|rcsb pdb:5USP|rcsb pdb:5USS|rcsb pdb:5USV|rcsb pdb:5UU2|rcsb pdb:5UU3|rcsb pdb:5UU4|rcsb pdb:5VIZ|rcsb pdb:5WBT|rcsb pdb:5WDM|rcsb pdb:5WOB|rcsb pdb:6B3Q|rcsb pdb:6B70|rcsb pdb:6BFC|rcsb pdb:6CE7|rcsb pdb:6CE9|rcsb pdb:6CEB|rcsb pdb:6CK2|rcsb pdb:6GNQ|rcsb pdb:6GV0|rcsb pdb:6H3M|rcsb pdb:6HN5|rcsb pdb:6JR3|rcsb pdb:6K59|rcsb pdb:6NWV|rcsb pdb:6O17|rcsb pdb:6P4Z|rcsb pdb:6S34|rcsb pdb:6S4I|rcsb pdb:6S4J|rcsb pdb:6SOF|rcsb pdb:6TC2|rcsb pdb:6TYH|rcsb pdb:6U46|rcsb pdb:6VEP|rcsb pdb:6VER|rcsb pdb:6VES|rcsb pdb:6VET|rcsb pdb:6X4X|rcsb pdb:6Z7W|rcsb pdb:6Z7Y|rcsb pdb:7BW7|rcsb pdb:7BW8|rcsb pdb:7BWA|rcsb pdb:7NHU|reactome:R-HSA-210745|reactome:R-HSA-264876|reactome:R-HSA-422085|reactome:R-HSA-422356|reactome:R-HSA-6807878|reactome:R-HSA-6811558|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-74752|reactome:R-HSA-77387|reactome:R-HSA-9615017|reactome:R-HSA-977225|rcsb pdb:6JK8|ensembl:ENSG00000254647(gene)|ensembl:ENST00000250971(transcript)|ensembl:ENST00000381330(transcript)|ensembl:ENST00000397262(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002020"(protease binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|refseq:NP_001172026.1|refseq:NP_000198.1|refseq:NP_001172027.1|dip:DIP-6024N|mint:MINT-8413747(identity) refseq:NP_001278826.1|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006521"(regulation of cellular amino acid metabolic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010750"(positive regulation of nitric oxide mediated signal transduction)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030133"(transport vesicle)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031904"(endosome lumen)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038060"(nitric oxide-cGMP-mediated signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045818"(negative regulation of glycogen catabolic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046631"(alpha-beta T cell activation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050890"(cognition)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0005179"(hormone activity)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000252"(negative regulation of feeding behavior)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|mint:P01308|rcsb pdb:1A7F|rcsb pdb:1AI0|rcsb pdb:1AIY|rcsb pdb:1B9E|rcsb pdb:1BEN|rcsb pdb:1EFE|rcsb pdb:1EV3|rcsb pdb:1EV6|rcsb pdb:1EVR|rcsb pdb:1FU2|rcsb pdb:1FUB|rcsb pdb:1G7A|rcsb pdb:1G7B|rcsb pdb:1GUJ|rcsb pdb:1HIQ|rcsb pdb:1HIS|rcsb pdb:1HIT|rcsb pdb:1HLS|rcsb pdb:1HTV|rcsb pdb:1HUI|rcsb pdb:1IOG|rcsb pdb:1IOH|rcsb pdb:1J73|rcsb pdb:1JCA|rcsb pdb:1JCO|rcsb pdb:1JK8|rcsb pdb:1K3M|rcsb pdb:1KMF|rcsb pdb:1LKQ|rcsb pdb:1LPH|rcsb pdb:1MHI|rcsb pdb:1MHJ|rcsb pdb:1MSO|rcsb pdb:1OS3|rcsb pdb:1OS4|rcsb pdb:1Q4V|rcsb pdb:1QIY|rcsb pdb:1QIZ|rcsb pdb:1QJ0|rcsb pdb:1RWE|rcsb pdb:1SF1|rcsb pdb:1SJT|rcsb pdb:1SJU|rcsb pdb:1T0C|rcsb pdb:1T1K|rcsb pdb:1T1P|rcsb pdb:1T1Q|rcsb pdb:1TRZ|rcsb pdb:1TYL|rcsb pdb:1TYM|rcsb pdb:1UZ9|rcsb pdb:1VKT|rcsb pdb:1W8P|rcsb pdb:1XDA|rcsb pdb:1XGL|rcsb pdb:1XW7|rcsb pdb:1ZEG|rcsb pdb:1ZEH|rcsb pdb:1ZNJ|rcsb pdb:2AIY|rcsb pdb:2C8Q|rcsb pdb:2C8R|rcsb pdb:2CEU|rcsb pdb:2G54|rcsb pdb:2G56|rcsb pdb:2H67|rcsb pdb:2HH4|rcsb pdb:2HHO|rcsb pdb:2HIU|rcsb pdb:2JMN|rcsb pdb:2JUM|rcsb pdb:2JUU|rcsb pdb:2JUV|rcsb pdb:2JZQ|rcsb pdb:2K91|rcsb pdb:2K9R|rcsb pdb:2KJJ|rcsb pdb:2KJU|rcsb pdb:2JV1|rcsb pdb:2KQP|rcsb pdb:2KQQ|rcsb pdb:2KXK|rcsb pdb:2L1Y|rcsb pdb:2L1Z|rcsb pdb:2LGB|rcsb pdb:2LWZ|rcsb pdb:2M1D|rcsb pdb:2M1E|rcsb pdb:2M2M|rcsb pdb:2M2N|rcsb pdb:2M2O|rcsb pdb:2M2P|rcsb pdb:2MLI|rcsb pdb:2MPG|rcsb pdb:2MPI|rcsb pdb:2MVC|rcsb pdb:2MVD|rcsb pdb:2N2V|rcsb pdb:2N2W|rcsb pdb:2N2X|rcsb pdb:2OLY|rcsb pdb:2OLZ|rcsb pdb:2OM0|rcsb pdb:2OM1|rcsb pdb:2OMG|rcsb pdb:2OMH|rcsb pdb:2OMI|rcsb pdb:2OMQ|rcsb pdb:2QIU|rcsb pdb:2R34|rcsb pdb:2R35|rcsb pdb:2R36|rcsb pdb:2RN5|rcsb pdb:2VJZ|rcsb pdb:2VK0|rcsb pdb:2W44|rcsb pdb:2WBY|rcsb pdb:2WC0|rcsb pdb:2WRU|rcsb pdb:2WRV|rcsb pdb:2WRW|rcsb pdb:2WRX|rcsb pdb:2WS0|rcsb pdb:2WS1|rcsb pdb:2WS4|rcsb pdb:2WS6|rcsb pdb:2WS7|rcsb pdb:3AIY|rcsb pdb:3BXQ|rcsb pdb:3E7Y|rcsb pdb:3E7Z|rcsb pdb:3EXX|rcsb pdb:3FQ9|rcsb pdb:3HYD|rcsb pdb:3I3Z|rcsb pdb:3I40|rcsb pdb:3ILG|rcsb pdb:3INC|rcsb pdb:3IR0|rcsb pdb:3JSD|rcsb pdb:3KQ6|rcsb pdb:3P2X|rcsb pdb:3P33|rcsb pdb:3Q6E|rcsb pdb:3ROV|rcsb pdb:3TT8|rcsb pdb:3U4N|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V19|rcsb pdb:3V1G|rcsb pdb:3W11|rcsb pdb:3W12|rcsb pdb:3W13|rcsb pdb:3W7Y|rcsb pdb:3W7Z|rcsb pdb:3W80|rcsb pdb:3ZI3|rcsb pdb:3ZQR|rcsb pdb:3ZS2|rcsb pdb:3ZU1|rcsb pdb:4AIY|rcsb pdb:4AJX|rcsb pdb:4AJZ|rcsb pdb:4AK0|rcsb pdb:4AKJ|rcsb pdb:4CXL|rcsb pdb:4CXN|rcsb pdb:4CY7|rcsb pdb:4EFX|rcsb pdb:4EWW|rcsb pdb:4EWX|rcsb pdb:4EWZ|rcsb pdb:4EX0|rcsb pdb:4EX1|rcsb pdb:4EXX|rcsb pdb:4EY1|rcsb pdb:4EY9|rcsb pdb:4EYD|rcsb pdb:4EYN|rcsb pdb:4EYP|rcsb pdb:4F0N|rcsb pdb:4F0O|rcsb pdb:4F1A|rcsb pdb:4F1B|rcsb pdb:4F1C|rcsb pdb:4F1D|rcsb pdb:4F1F|rcsb pdb:4F1G|rcsb pdb:4F4T|rcsb pdb:4F4V|rcsb pdb:4F51|rcsb pdb:4F8F|rcsb pdb:4FG3|rcsb pdb:4FKA|rcsb pdb:4GBC|rcsb pdb:4GBI|rcsb pdb:4GBK|rcsb pdb:4GBL|rcsb pdb:4GBN|rcsb pdb:4IUZ|rcsb pdb:4IYD|rcsb pdb:4IYF|rcsb pdb:4NIB|rcsb pdb:4OGA|rcsb pdb:4P65|rcsb pdb:4RXW|rcsb pdb:4UNE|rcsb pdb:4UNG|rcsb pdb:4UNH|rcsb pdb:4WDI|rcsb pdb:4XC4|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5AIY|rcsb pdb:5BOQ|rcsb pdb:5BPO|rcsb pdb:5BQQ|rcsb pdb:5BTS|rcsb pdb:5C0D|rcsb pdb:5CJO|rcsb pdb:5CNY|rcsb pdb:5CO2|rcsb pdb:5CO6|rcsb pdb:5CO9|rcsb pdb:5E7W|rcsb pdb:5EMS|rcsb pdb:5EN9|rcsb pdb:5ENA|rcsb pdb:5HPR|rcsb pdb:5HPU|rcsb pdb:5HQI|rcsb pdb:5HRQ|rcsb pdb:5HYJ|rcsb pdb:5MAM|rcsb pdb:5MHD|rcsb pdb:5MT3|rcsb pdb:5MT9|rcsb pdb:5MWQ|rcsb pdb:5T7R|rcsb pdb:5UDP|rcsb pdb:5UOZ|rcsb pdb:5UQA|rcsb pdb:5URT|rcsb pdb:5URU|rcsb pdb:5USP|rcsb pdb:5USS|rcsb pdb:5USV|rcsb pdb:5UU2|rcsb pdb:5UU3|rcsb pdb:5UU4|rcsb pdb:5VIZ|rcsb pdb:5WBT|rcsb pdb:5WDM|rcsb pdb:5WOB|rcsb pdb:6B3Q|rcsb pdb:6B70|rcsb pdb:6BFC|rcsb pdb:6CE7|rcsb pdb:6CE9|rcsb pdb:6CEB|rcsb pdb:6CK2|rcsb pdb:6GNQ|rcsb pdb:6GV0|rcsb pdb:6H3M|rcsb pdb:6HN5|rcsb pdb:6JR3|rcsb pdb:6K59|rcsb pdb:6NWV|rcsb pdb:6O17|rcsb pdb:6P4Z|rcsb pdb:6S34|rcsb pdb:6S4I|rcsb pdb:6S4J|rcsb pdb:6SOF|rcsb pdb:6TC2|rcsb pdb:6TYH|rcsb pdb:6U46|rcsb pdb:6VEP|rcsb pdb:6VER|rcsb pdb:6VES|rcsb pdb:6VET|rcsb pdb:6X4X|rcsb pdb:6Z7W|rcsb pdb:6Z7Y|rcsb pdb:7BW7|rcsb pdb:7BW8|rcsb pdb:7BWA|rcsb pdb:7NHU|reactome:R-HSA-210745|reactome:R-HSA-264876|reactome:R-HSA-422085|reactome:R-HSA-422356|reactome:R-HSA-6807878|reactome:R-HSA-6811558|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-74752|reactome:R-HSA-77387|reactome:R-HSA-9615017|reactome:R-HSA-977225|rcsb pdb:6JK8|ensembl:ENSG00000254647(gene)|ensembl:ENST00000250971(transcript)|ensembl:ENST00000381330(transcript)|ensembl:ENST00000397262(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002020"(protease binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|refseq:NP_001172026.1|refseq:NP_000198.1|refseq:NP_001172027.1|dip:DIP-6024N|mint:MINT-8413745(identity) - function:Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver|comment:mint|comment:homomint|function:"Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730]" function:Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver|comment:mint|comment:homomint|function:"Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730]" figure legend:f4e|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/06 2014/10/16 rogid:RFnbvRnJ3AIA4j1Se0KPx0RFhD89606 rogid:RFnbvRnJ3AIA4j1Se0KPx0RFhD89606 intact-crc:C1A8D113A8F7F253|rigid:G7zQotcx6N1ROS55MQ1QCp3vXiU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01317 uniprotkb:P01317 intact:EBI-3989070 intact:EBI-3989070 psi-mi:ins_bovin(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:ins_bovin(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:"MI:0964"(infrared spectroscopy) Babenko et al. (2013) pubmed:23416304|mint:MINT-8413634|mint:d-12-02034r1 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8438017|mint:MINT-8413650 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-52901N|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0009306"(protein secretion)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032094"(response to food)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035938"(estradiol secretion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1903431"(positive regulation of cell maturation)|go:"GO:1903488"(negative regulation of lactation)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1903524"(positive regulation of blood circulation)|go:"GO:1903544"(response to butyrate)|go:"GO:1903576"(response to L-arginine)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|rcsb pdb:1APH|rcsb pdb:1BPH|rcsb pdb:1CPH|rcsb pdb:1DPH|rcsb pdb:1HO0|rcsb pdb:1PID|rcsb pdb:2A3G|rcsb pdb:2BN1|rcsb pdb:2BN3|rcsb pdb:2INS|rcsb pdb:2ZP6|rcsb pdb:4BS3|rcsb pdb:4E7T|rcsb pdb:4E7U|rcsb pdb:4E7V|rcsb pdb:4I5Y|rcsb pdb:4I5Z|rcsb pdb:4IDW|rcsb pdb:4IHN|rcsb pdb:4M4F|rcsb pdb:4M4H|rcsb pdb:4M4I|rcsb pdb:4M4J|rcsb pdb:4M4L|rcsb pdb:4M4M|rcsb pdb:5AZZ|rcsb pdb:5KQV|rcsb pdb:5MIZ|rcsb pdb:6KH9|rcsb pdb:6KHA|rcsb pdb:6OR0|rcsb pdb:6Q8Q|rcsb pdb:6QQ7|rcsb pdb:6QQG|rcsb pdb:6QRH|rcsb pdb:6QRK|rcsb pdb:6ZHB|rcsb pdb:6ZI8|rcsb pdb:7ELJ|rcsb pdb:6KH8|mint:MINT-8413654(identity) dip:DIP-52901N|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0009306"(protein secretion)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032094"(response to food)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035938"(estradiol secretion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1903431"(positive regulation of cell maturation)|go:"GO:1903488"(negative regulation of lactation)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1903524"(positive regulation of blood circulation)|go:"GO:1903544"(response to butyrate)|go:"GO:1903576"(response to L-arginine)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|rcsb pdb:1APH|rcsb pdb:1BPH|rcsb pdb:1CPH|rcsb pdb:1DPH|rcsb pdb:1HO0|rcsb pdb:1PID|rcsb pdb:2A3G|rcsb pdb:2BN1|rcsb pdb:2BN3|rcsb pdb:2INS|rcsb pdb:2ZP6|rcsb pdb:4BS3|rcsb pdb:4E7T|rcsb pdb:4E7U|rcsb pdb:4E7V|rcsb pdb:4I5Y|rcsb pdb:4I5Z|rcsb pdb:4IDW|rcsb pdb:4IHN|rcsb pdb:4M4F|rcsb pdb:4M4H|rcsb pdb:4M4I|rcsb pdb:4M4J|rcsb pdb:4M4L|rcsb pdb:4M4M|rcsb pdb:5AZZ|rcsb pdb:5KQV|rcsb pdb:5MIZ|rcsb pdb:6KH9|rcsb pdb:6KHA|rcsb pdb:6OR0|rcsb pdb:6Q8Q|rcsb pdb:6QQ7|rcsb pdb:6QQG|rcsb pdb:6QRH|rcsb pdb:6QRK|rcsb pdb:6ZHB|rcsb pdb:6ZI8|rcsb pdb:7ELJ|rcsb pdb:6KH8|mint:MINT-8413652(identity) - - - figure legend:f2e|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/06 2014/10/16 rogid:CgQ4BPd2mlhYt73TJXbE6V9GJYs9913 rogid:CgQ4BPd2mlhYt73TJXbE6V9GJYs9913 intact-crc:9DF8532E6DCA9081|rigid:hUyIEGMcFAdui5udi+emCJNQyNc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01315 uniprotkb:P01315 intact:EBI-8437944|intact:MINT-1505666|uniprotkb:Q9TSJ5|ensembl:ENSSSCP00000044635|ensembl:ENSSSCP00015002060|ensembl:ENSSSCP00025013482|ensembl:ENSSSCP00030047908|ensembl:ENSSSCP00035009642|ensembl:ENSSSCP00040009750|ensembl:ENSSSCP00045005838|ensembl:ENSSSCP00050004834|ensembl:ENSSSCP00055025559|ensembl:ENSSSCP00060020355|ensembl:ENSSSCP00065038365|ensembl:ENSSSCP00070024989 intact:EBI-8437944|intact:MINT-1505666|uniprotkb:Q9TSJ5|ensembl:ENSSSCP00000044635|ensembl:ENSSSCP00015002060|ensembl:ENSSSCP00025013482|ensembl:ENSSSCP00030047908|ensembl:ENSSSCP00035009642|ensembl:ENSSSCP00040009750|ensembl:ENSSSCP00045005838|ensembl:ENSSSCP00050004834|ensembl:ENSSSCP00055025559|ensembl:ENSSSCP00060020355|ensembl:ENSSSCP00065038365|ensembl:ENSSSCP00070024989 psi-mi:ins_pig(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:ins_pig(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:"MI:0016"(circular dichroism) Babenko et al. (2013) pubmed:23416304|mint:MINT-8413634|mint:d-12-02034r1 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8438076|mint:MINT-8413691 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001103242.1|ensembl:ENSSSCG00000033740(gene)|ensembl:ENSSSCG00015004005(gene)|ensembl:ENSSSCG00025023773(gene)|ensembl:ENSSSCG00030073948(gene)|ensembl:ENSSSCG00035019667(gene)|ensembl:ENSSSCG00040017207(gene)|ensembl:ENSSSCG00045005189(gene)|ensembl:ENSSSCG00050008342(gene)|ensembl:ENSSSCG00055016292(gene)|ensembl:ENSSSCG00060035069(gene)|ensembl:ENSSSCG00065063887(gene)|ensembl:ENSSSCG00070015252(gene)|ensembl:ENSSSCT00000064136(transcript)|ensembl:ENSSSCT00015005290(transcript)|ensembl:ENSSSCT00025032226(transcript)|ensembl:ENSSSCT00030103634(transcript)|ensembl:ENSSSCT00035025488(transcript)|ensembl:ENSSSCT00040023180(transcript)|ensembl:ENSSSCT00045008618(transcript)|ensembl:ENSSSCT00050011348(transcript)|ensembl:ENSSSCT00055032104(transcript)|ensembl:ENSSSCT00060047539(transcript)|ensembl:ENSSSCT00065087685(transcript)|ensembl:ENSSSCT00070029958(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002020"(protease binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006521"(regulation of cellular amino acid metabolic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0010750"(positive regulation of nitric oxide mediated signal transduction)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0038060"(nitric oxide-cGMP-mediated signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045818"(negative regulation of glycogen catabolic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046631"(alpha-beta T cell activation)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903576"(response to L-arginine)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000252"(negative regulation of feeding behavior)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|rcsb pdb:1B17|rcsb pdb:1B18|rcsb pdb:1B19|rcsb pdb:1B2A|rcsb pdb:1B2B|rcsb pdb:1B2C|rcsb pdb:1B2D|rcsb pdb:1B2E|rcsb pdb:1B2F|rcsb pdb:1B2G|rcsb pdb:1DEI|rcsb pdb:1IZA|rcsb pdb:1IZB|rcsb pdb:1M5A|rcsb pdb:1MPJ|rcsb pdb:1SDB|rcsb pdb:1WAV|rcsb pdb:1ZEI|rcsb pdb:1ZNI|rcsb pdb:2EFA|rcsb pdb:2G4M|rcsb pdb:2TCI|rcsb pdb:2ZPP|rcsb pdb:3FHP|rcsb pdb:3GKY|rcsb pdb:3INS|rcsb pdb:3MTH|rcsb pdb:3RTO|rcsb pdb:3T2A|rcsb pdb:4A7E|rcsb pdb:4INS|rcsb pdb:5D52|rcsb pdb:5D53|rcsb pdb:5D54|rcsb pdb:5D5E|rcsb pdb:5FB6|rcsb pdb:5LIS|rcsb pdb:6INS|rcsb pdb:6Z7Z|rcsb pdb:7INS|rcsb pdb:9INS|mint:MINT-8413693(identity) refseq:NP_001103242.1|ensembl:ENSSSCG00000033740(gene)|ensembl:ENSSSCG00015004005(gene)|ensembl:ENSSSCG00025023773(gene)|ensembl:ENSSSCG00030073948(gene)|ensembl:ENSSSCG00035019667(gene)|ensembl:ENSSSCG00040017207(gene)|ensembl:ENSSSCG00045005189(gene)|ensembl:ENSSSCG00050008342(gene)|ensembl:ENSSSCG00055016292(gene)|ensembl:ENSSSCG00060035069(gene)|ensembl:ENSSSCG00065063887(gene)|ensembl:ENSSSCG00070015252(gene)|ensembl:ENSSSCT00000064136(transcript)|ensembl:ENSSSCT00015005290(transcript)|ensembl:ENSSSCT00025032226(transcript)|ensembl:ENSSSCT00030103634(transcript)|ensembl:ENSSSCT00035025488(transcript)|ensembl:ENSSSCT00040023180(transcript)|ensembl:ENSSSCT00045008618(transcript)|ensembl:ENSSSCT00050011348(transcript)|ensembl:ENSSSCT00055032104(transcript)|ensembl:ENSSSCT00060047539(transcript)|ensembl:ENSSSCT00065087685(transcript)|ensembl:ENSSSCT00070029958(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002020"(protease binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006521"(regulation of cellular amino acid metabolic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009101"(glycoprotein biosynthetic process)|go:"GO:0010750"(positive regulation of nitric oxide mediated signal transduction)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0038060"(nitric oxide-cGMP-mediated signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045818"(negative regulation of glycogen catabolic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046631"(alpha-beta T cell activation)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903576"(response to L-arginine)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000252"(negative regulation of feeding behavior)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|rcsb pdb:1B17|rcsb pdb:1B18|rcsb pdb:1B19|rcsb pdb:1B2A|rcsb pdb:1B2B|rcsb pdb:1B2C|rcsb pdb:1B2D|rcsb pdb:1B2E|rcsb pdb:1B2F|rcsb pdb:1B2G|rcsb pdb:1DEI|rcsb pdb:1IZA|rcsb pdb:1IZB|rcsb pdb:1M5A|rcsb pdb:1MPJ|rcsb pdb:1SDB|rcsb pdb:1WAV|rcsb pdb:1ZEI|rcsb pdb:1ZNI|rcsb pdb:2EFA|rcsb pdb:2G4M|rcsb pdb:2TCI|rcsb pdb:2ZPP|rcsb pdb:3FHP|rcsb pdb:3GKY|rcsb pdb:3INS|rcsb pdb:3MTH|rcsb pdb:3RTO|rcsb pdb:3T2A|rcsb pdb:4A7E|rcsb pdb:4INS|rcsb pdb:5D52|rcsb pdb:5D53|rcsb pdb:5D54|rcsb pdb:5D5E|rcsb pdb:5FB6|rcsb pdb:5LIS|rcsb pdb:6INS|rcsb pdb:6Z7Z|rcsb pdb:7INS|rcsb pdb:9INS|mint:MINT-8413695(identity) - function:Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver|comment:mint function:Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver|comment:mint figure legend:f3|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/06 2014/10/16 rogid:jJtfIrm2VcLfHHHuPKRkLde+nW09823 rogid:jJtfIrm2VcLfHHHuPKRkLde+nW09823 intact-crc:6D6EA1E1F63F3133|rigid:Kel3BPpjGvsKkiK0z6qwVwXWg4M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01308 uniprotkb:P01308 intact:EBI-7090529|ensembl:ENSP00000250971|ensembl:ENSP00000370731|ensembl:ENSP00000380432|uniprotkb:Q5EEX2|intact:MINT-106847 intact:EBI-7090529|ensembl:ENSP00000250971|ensembl:ENSP00000370731|ensembl:ENSP00000380432|uniprotkb:Q5EEX2|intact:MINT-106847 psi-mi:ins_human(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:ins_human(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:"MI:0016"(circular dichroism) Babenko et al. (2013) pubmed:23416304|mint:MINT-8413634|mint:d-12-02034r1 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8438064|mint:MINT-8413680 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278826.1|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006521"(regulation of cellular amino acid metabolic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010750"(positive regulation of nitric oxide mediated signal transduction)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030133"(transport vesicle)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031904"(endosome lumen)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038060"(nitric oxide-cGMP-mediated signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045818"(negative regulation of glycogen catabolic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046631"(alpha-beta T cell activation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050890"(cognition)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0005179"(hormone activity)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000252"(negative regulation of feeding behavior)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|mint:P01308|rcsb pdb:1A7F|rcsb pdb:1AI0|rcsb pdb:1AIY|rcsb pdb:1B9E|rcsb pdb:1BEN|rcsb pdb:1EFE|rcsb pdb:1EV3|rcsb pdb:1EV6|rcsb pdb:1EVR|rcsb pdb:1FU2|rcsb pdb:1FUB|rcsb pdb:1G7A|rcsb pdb:1G7B|rcsb pdb:1GUJ|rcsb pdb:1HIQ|rcsb pdb:1HIS|rcsb pdb:1HIT|rcsb pdb:1HLS|rcsb pdb:1HTV|rcsb pdb:1HUI|rcsb pdb:1IOG|rcsb pdb:1IOH|rcsb pdb:1J73|rcsb pdb:1JCA|rcsb pdb:1JCO|rcsb pdb:1JK8|rcsb pdb:1K3M|rcsb pdb:1KMF|rcsb pdb:1LKQ|rcsb pdb:1LPH|rcsb pdb:1MHI|rcsb pdb:1MHJ|rcsb pdb:1MSO|rcsb pdb:1OS3|rcsb pdb:1OS4|rcsb pdb:1Q4V|rcsb pdb:1QIY|rcsb pdb:1QIZ|rcsb pdb:1QJ0|rcsb pdb:1RWE|rcsb pdb:1SF1|rcsb pdb:1SJT|rcsb pdb:1SJU|rcsb pdb:1T0C|rcsb pdb:1T1K|rcsb pdb:1T1P|rcsb pdb:1T1Q|rcsb pdb:1TRZ|rcsb pdb:1TYL|rcsb pdb:1TYM|rcsb pdb:1UZ9|rcsb pdb:1VKT|rcsb pdb:1W8P|rcsb pdb:1XDA|rcsb pdb:1XGL|rcsb pdb:1XW7|rcsb pdb:1ZEG|rcsb pdb:1ZEH|rcsb pdb:1ZNJ|rcsb pdb:2AIY|rcsb pdb:2C8Q|rcsb pdb:2C8R|rcsb pdb:2CEU|rcsb pdb:2G54|rcsb pdb:2G56|rcsb pdb:2H67|rcsb pdb:2HH4|rcsb pdb:2HHO|rcsb pdb:2HIU|rcsb pdb:2JMN|rcsb pdb:2JUM|rcsb pdb:2JUU|rcsb pdb:2JUV|rcsb pdb:2JZQ|rcsb pdb:2K91|rcsb pdb:2K9R|rcsb pdb:2KJJ|rcsb pdb:2KJU|rcsb pdb:2JV1|rcsb pdb:2KQP|rcsb pdb:2KQQ|rcsb pdb:2KXK|rcsb pdb:2L1Y|rcsb pdb:2L1Z|rcsb pdb:2LGB|rcsb pdb:2LWZ|rcsb pdb:2M1D|rcsb pdb:2M1E|rcsb pdb:2M2M|rcsb pdb:2M2N|rcsb pdb:2M2O|rcsb pdb:2M2P|rcsb pdb:2MLI|rcsb pdb:2MPG|rcsb pdb:2MPI|rcsb pdb:2MVC|rcsb pdb:2MVD|rcsb pdb:2N2V|rcsb pdb:2N2W|rcsb pdb:2N2X|rcsb pdb:2OLY|rcsb pdb:2OLZ|rcsb pdb:2OM0|rcsb pdb:2OM1|rcsb pdb:2OMG|rcsb pdb:2OMH|rcsb pdb:2OMI|rcsb pdb:2OMQ|rcsb pdb:2QIU|rcsb pdb:2R34|rcsb pdb:2R35|rcsb pdb:2R36|rcsb pdb:2RN5|rcsb pdb:2VJZ|rcsb pdb:2VK0|rcsb pdb:2W44|rcsb pdb:2WBY|rcsb pdb:2WC0|rcsb pdb:2WRU|rcsb pdb:2WRV|rcsb pdb:2WRW|rcsb pdb:2WRX|rcsb pdb:2WS0|rcsb pdb:2WS1|rcsb pdb:2WS4|rcsb pdb:2WS6|rcsb pdb:2WS7|rcsb pdb:3AIY|rcsb pdb:3BXQ|rcsb pdb:3E7Y|rcsb pdb:3E7Z|rcsb pdb:3EXX|rcsb pdb:3FQ9|rcsb pdb:3HYD|rcsb pdb:3I3Z|rcsb pdb:3I40|rcsb pdb:3ILG|rcsb pdb:3INC|rcsb pdb:3IR0|rcsb pdb:3JSD|rcsb pdb:3KQ6|rcsb pdb:3P2X|rcsb pdb:3P33|rcsb pdb:3Q6E|rcsb pdb:3ROV|rcsb pdb:3TT8|rcsb pdb:3U4N|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V19|rcsb pdb:3V1G|rcsb pdb:3W11|rcsb pdb:3W12|rcsb pdb:3W13|rcsb pdb:3W7Y|rcsb pdb:3W7Z|rcsb pdb:3W80|rcsb pdb:3ZI3|rcsb pdb:3ZQR|rcsb pdb:3ZS2|rcsb pdb:3ZU1|rcsb pdb:4AIY|rcsb pdb:4AJX|rcsb pdb:4AJZ|rcsb pdb:4AK0|rcsb pdb:4AKJ|rcsb pdb:4CXL|rcsb pdb:4CXN|rcsb pdb:4CY7|rcsb pdb:4EFX|rcsb pdb:4EWW|rcsb pdb:4EWX|rcsb pdb:4EWZ|rcsb pdb:4EX0|rcsb pdb:4EX1|rcsb pdb:4EXX|rcsb pdb:4EY1|rcsb pdb:4EY9|rcsb pdb:4EYD|rcsb pdb:4EYN|rcsb pdb:4EYP|rcsb pdb:4F0N|rcsb pdb:4F0O|rcsb pdb:4F1A|rcsb pdb:4F1B|rcsb pdb:4F1C|rcsb pdb:4F1D|rcsb pdb:4F1F|rcsb pdb:4F1G|rcsb pdb:4F4T|rcsb pdb:4F4V|rcsb pdb:4F51|rcsb pdb:4F8F|rcsb pdb:4FG3|rcsb pdb:4FKA|rcsb pdb:4GBC|rcsb pdb:4GBI|rcsb pdb:4GBK|rcsb pdb:4GBL|rcsb pdb:4GBN|rcsb pdb:4IUZ|rcsb pdb:4IYD|rcsb pdb:4IYF|rcsb pdb:4NIB|rcsb pdb:4OGA|rcsb pdb:4P65|rcsb pdb:4RXW|rcsb pdb:4UNE|rcsb pdb:4UNG|rcsb pdb:4UNH|rcsb pdb:4WDI|rcsb pdb:4XC4|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5AIY|rcsb pdb:5BOQ|rcsb pdb:5BPO|rcsb pdb:5BQQ|rcsb pdb:5BTS|rcsb pdb:5C0D|rcsb pdb:5CJO|rcsb pdb:5CNY|rcsb pdb:5CO2|rcsb pdb:5CO6|rcsb pdb:5CO9|rcsb pdb:5E7W|rcsb pdb:5EMS|rcsb pdb:5EN9|rcsb pdb:5ENA|rcsb pdb:5HPR|rcsb pdb:5HPU|rcsb pdb:5HQI|rcsb pdb:5HRQ|rcsb pdb:5HYJ|rcsb pdb:5MAM|rcsb pdb:5MHD|rcsb pdb:5MT3|rcsb pdb:5MT9|rcsb pdb:5MWQ|rcsb pdb:5T7R|rcsb pdb:5UDP|rcsb pdb:5UOZ|rcsb pdb:5UQA|rcsb pdb:5URT|rcsb pdb:5URU|rcsb pdb:5USP|rcsb pdb:5USS|rcsb pdb:5USV|rcsb pdb:5UU2|rcsb pdb:5UU3|rcsb pdb:5UU4|rcsb pdb:5VIZ|rcsb pdb:5WBT|rcsb pdb:5WDM|rcsb pdb:5WOB|rcsb pdb:6B3Q|rcsb pdb:6B70|rcsb pdb:6BFC|rcsb pdb:6CE7|rcsb pdb:6CE9|rcsb pdb:6CEB|rcsb pdb:6CK2|rcsb pdb:6GNQ|rcsb pdb:6GV0|rcsb pdb:6H3M|rcsb pdb:6HN5|rcsb pdb:6JR3|rcsb pdb:6K59|rcsb pdb:6NWV|rcsb pdb:6O17|rcsb pdb:6P4Z|rcsb pdb:6S34|rcsb pdb:6S4I|rcsb pdb:6S4J|rcsb pdb:6SOF|rcsb pdb:6TC2|rcsb pdb:6TYH|rcsb pdb:6U46|rcsb pdb:6VEP|rcsb pdb:6VER|rcsb pdb:6VES|rcsb pdb:6VET|rcsb pdb:6X4X|rcsb pdb:6Z7W|rcsb pdb:6Z7Y|rcsb pdb:7BW7|rcsb pdb:7BW8|rcsb pdb:7BWA|rcsb pdb:7NHU|reactome:R-HSA-210745|reactome:R-HSA-264876|reactome:R-HSA-422085|reactome:R-HSA-422356|reactome:R-HSA-6807878|reactome:R-HSA-6811558|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-74752|reactome:R-HSA-77387|reactome:R-HSA-9615017|reactome:R-HSA-977225|rcsb pdb:6JK8|ensembl:ENSG00000254647(gene)|ensembl:ENST00000250971(transcript)|ensembl:ENST00000381330(transcript)|ensembl:ENST00000397262(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002020"(protease binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|refseq:NP_001172026.1|refseq:NP_000198.1|refseq:NP_001172027.1|dip:DIP-6024N|mint:MINT-8413682(identity) refseq:NP_001278826.1|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006521"(regulation of cellular amino acid metabolic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010750"(positive regulation of nitric oxide mediated signal transduction)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030133"(transport vesicle)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031904"(endosome lumen)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033861"("negative regulation of NAD(P)H oxidase activity")|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038060"(nitric oxide-cGMP-mediated signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045818"(negative regulation of glycogen catabolic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046631"(alpha-beta T cell activation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050890"(cognition)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0005179"(hormone activity)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000252"(negative regulation of feeding behavior)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|mint:P01308|rcsb pdb:1A7F|rcsb pdb:1AI0|rcsb pdb:1AIY|rcsb pdb:1B9E|rcsb pdb:1BEN|rcsb pdb:1EFE|rcsb pdb:1EV3|rcsb pdb:1EV6|rcsb pdb:1EVR|rcsb pdb:1FU2|rcsb pdb:1FUB|rcsb pdb:1G7A|rcsb pdb:1G7B|rcsb pdb:1GUJ|rcsb pdb:1HIQ|rcsb pdb:1HIS|rcsb pdb:1HIT|rcsb pdb:1HLS|rcsb pdb:1HTV|rcsb pdb:1HUI|rcsb pdb:1IOG|rcsb pdb:1IOH|rcsb pdb:1J73|rcsb pdb:1JCA|rcsb pdb:1JCO|rcsb pdb:1JK8|rcsb pdb:1K3M|rcsb pdb:1KMF|rcsb pdb:1LKQ|rcsb pdb:1LPH|rcsb pdb:1MHI|rcsb pdb:1MHJ|rcsb pdb:1MSO|rcsb pdb:1OS3|rcsb pdb:1OS4|rcsb pdb:1Q4V|rcsb pdb:1QIY|rcsb pdb:1QIZ|rcsb pdb:1QJ0|rcsb pdb:1RWE|rcsb pdb:1SF1|rcsb pdb:1SJT|rcsb pdb:1SJU|rcsb pdb:1T0C|rcsb pdb:1T1K|rcsb pdb:1T1P|rcsb pdb:1T1Q|rcsb pdb:1TRZ|rcsb pdb:1TYL|rcsb pdb:1TYM|rcsb pdb:1UZ9|rcsb pdb:1VKT|rcsb pdb:1W8P|rcsb pdb:1XDA|rcsb pdb:1XGL|rcsb pdb:1XW7|rcsb pdb:1ZEG|rcsb pdb:1ZEH|rcsb pdb:1ZNJ|rcsb pdb:2AIY|rcsb pdb:2C8Q|rcsb pdb:2C8R|rcsb pdb:2CEU|rcsb pdb:2G54|rcsb pdb:2G56|rcsb pdb:2H67|rcsb pdb:2HH4|rcsb pdb:2HHO|rcsb pdb:2HIU|rcsb pdb:2JMN|rcsb pdb:2JUM|rcsb pdb:2JUU|rcsb pdb:2JUV|rcsb pdb:2JZQ|rcsb pdb:2K91|rcsb pdb:2K9R|rcsb pdb:2KJJ|rcsb pdb:2KJU|rcsb pdb:2JV1|rcsb pdb:2KQP|rcsb pdb:2KQQ|rcsb pdb:2KXK|rcsb pdb:2L1Y|rcsb pdb:2L1Z|rcsb pdb:2LGB|rcsb pdb:2LWZ|rcsb pdb:2M1D|rcsb pdb:2M1E|rcsb pdb:2M2M|rcsb pdb:2M2N|rcsb pdb:2M2O|rcsb pdb:2M2P|rcsb pdb:2MLI|rcsb pdb:2MPG|rcsb pdb:2MPI|rcsb pdb:2MVC|rcsb pdb:2MVD|rcsb pdb:2N2V|rcsb pdb:2N2W|rcsb pdb:2N2X|rcsb pdb:2OLY|rcsb pdb:2OLZ|rcsb pdb:2OM0|rcsb pdb:2OM1|rcsb pdb:2OMG|rcsb pdb:2OMH|rcsb pdb:2OMI|rcsb pdb:2OMQ|rcsb pdb:2QIU|rcsb pdb:2R34|rcsb pdb:2R35|rcsb pdb:2R36|rcsb pdb:2RN5|rcsb pdb:2VJZ|rcsb pdb:2VK0|rcsb pdb:2W44|rcsb pdb:2WBY|rcsb pdb:2WC0|rcsb pdb:2WRU|rcsb pdb:2WRV|rcsb pdb:2WRW|rcsb pdb:2WRX|rcsb pdb:2WS0|rcsb pdb:2WS1|rcsb pdb:2WS4|rcsb pdb:2WS6|rcsb pdb:2WS7|rcsb pdb:3AIY|rcsb pdb:3BXQ|rcsb pdb:3E7Y|rcsb pdb:3E7Z|rcsb pdb:3EXX|rcsb pdb:3FQ9|rcsb pdb:3HYD|rcsb pdb:3I3Z|rcsb pdb:3I40|rcsb pdb:3ILG|rcsb pdb:3INC|rcsb pdb:3IR0|rcsb pdb:3JSD|rcsb pdb:3KQ6|rcsb pdb:3P2X|rcsb pdb:3P33|rcsb pdb:3Q6E|rcsb pdb:3ROV|rcsb pdb:3TT8|rcsb pdb:3U4N|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V19|rcsb pdb:3V1G|rcsb pdb:3W11|rcsb pdb:3W12|rcsb pdb:3W13|rcsb pdb:3W7Y|rcsb pdb:3W7Z|rcsb pdb:3W80|rcsb pdb:3ZI3|rcsb pdb:3ZQR|rcsb pdb:3ZS2|rcsb pdb:3ZU1|rcsb pdb:4AIY|rcsb pdb:4AJX|rcsb pdb:4AJZ|rcsb pdb:4AK0|rcsb pdb:4AKJ|rcsb pdb:4CXL|rcsb pdb:4CXN|rcsb pdb:4CY7|rcsb pdb:4EFX|rcsb pdb:4EWW|rcsb pdb:4EWX|rcsb pdb:4EWZ|rcsb pdb:4EX0|rcsb pdb:4EX1|rcsb pdb:4EXX|rcsb pdb:4EY1|rcsb pdb:4EY9|rcsb pdb:4EYD|rcsb pdb:4EYN|rcsb pdb:4EYP|rcsb pdb:4F0N|rcsb pdb:4F0O|rcsb pdb:4F1A|rcsb pdb:4F1B|rcsb pdb:4F1C|rcsb pdb:4F1D|rcsb pdb:4F1F|rcsb pdb:4F1G|rcsb pdb:4F4T|rcsb pdb:4F4V|rcsb pdb:4F51|rcsb pdb:4F8F|rcsb pdb:4FG3|rcsb pdb:4FKA|rcsb pdb:4GBC|rcsb pdb:4GBI|rcsb pdb:4GBK|rcsb pdb:4GBL|rcsb pdb:4GBN|rcsb pdb:4IUZ|rcsb pdb:4IYD|rcsb pdb:4IYF|rcsb pdb:4NIB|rcsb pdb:4OGA|rcsb pdb:4P65|rcsb pdb:4RXW|rcsb pdb:4UNE|rcsb pdb:4UNG|rcsb pdb:4UNH|rcsb pdb:4WDI|rcsb pdb:4XC4|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5AIY|rcsb pdb:5BOQ|rcsb pdb:5BPO|rcsb pdb:5BQQ|rcsb pdb:5BTS|rcsb pdb:5C0D|rcsb pdb:5CJO|rcsb pdb:5CNY|rcsb pdb:5CO2|rcsb pdb:5CO6|rcsb pdb:5CO9|rcsb pdb:5E7W|rcsb pdb:5EMS|rcsb pdb:5EN9|rcsb pdb:5ENA|rcsb pdb:5HPR|rcsb pdb:5HPU|rcsb pdb:5HQI|rcsb pdb:5HRQ|rcsb pdb:5HYJ|rcsb pdb:5MAM|rcsb pdb:5MHD|rcsb pdb:5MT3|rcsb pdb:5MT9|rcsb pdb:5MWQ|rcsb pdb:5T7R|rcsb pdb:5UDP|rcsb pdb:5UOZ|rcsb pdb:5UQA|rcsb pdb:5URT|rcsb pdb:5URU|rcsb pdb:5USP|rcsb pdb:5USS|rcsb pdb:5USV|rcsb pdb:5UU2|rcsb pdb:5UU3|rcsb pdb:5UU4|rcsb pdb:5VIZ|rcsb pdb:5WBT|rcsb pdb:5WDM|rcsb pdb:5WOB|rcsb pdb:6B3Q|rcsb pdb:6B70|rcsb pdb:6BFC|rcsb pdb:6CE7|rcsb pdb:6CE9|rcsb pdb:6CEB|rcsb pdb:6CK2|rcsb pdb:6GNQ|rcsb pdb:6GV0|rcsb pdb:6H3M|rcsb pdb:6HN5|rcsb pdb:6JR3|rcsb pdb:6K59|rcsb pdb:6NWV|rcsb pdb:6O17|rcsb pdb:6P4Z|rcsb pdb:6S34|rcsb pdb:6S4I|rcsb pdb:6S4J|rcsb pdb:6SOF|rcsb pdb:6TC2|rcsb pdb:6TYH|rcsb pdb:6U46|rcsb pdb:6VEP|rcsb pdb:6VER|rcsb pdb:6VES|rcsb pdb:6VET|rcsb pdb:6X4X|rcsb pdb:6Z7W|rcsb pdb:6Z7Y|rcsb pdb:7BW7|rcsb pdb:7BW8|rcsb pdb:7BWA|rcsb pdb:7NHU|reactome:R-HSA-210745|reactome:R-HSA-264876|reactome:R-HSA-422085|reactome:R-HSA-422356|reactome:R-HSA-6807878|reactome:R-HSA-6811558|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-74752|reactome:R-HSA-77387|reactome:R-HSA-9615017|reactome:R-HSA-977225|rcsb pdb:6JK8|ensembl:ENSG00000254647(gene)|ensembl:ENST00000250971(transcript)|ensembl:ENST00000381330(transcript)|ensembl:ENST00000397262(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002020"(protease binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|refseq:NP_001172026.1|refseq:NP_000198.1|refseq:NP_001172027.1|dip:DIP-6024N|mint:MINT-8413684(identity) - function:Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver|comment:mint|comment:homomint|function:"Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730]" function:Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver|comment:mint|comment:homomint|function:"Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730]" figure legend:f3|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/06 2014/10/16 rogid:RFnbvRnJ3AIA4j1Se0KPx0RFhD89606 rogid:RFnbvRnJ3AIA4j1Se0KPx0RFhD89606 intact-crc:CBEB7CC34C4C8FB6|rigid:G7zQotcx6N1ROS55MQ1QCp3vXiU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01317 uniprotkb:P01317 intact:EBI-3989070 intact:EBI-3989070 psi-mi:ins_bovin(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:ins_bovin(display_long)|uniprotkb:INS(gene name)|psi-mi:INS(display_short) psi-mi:"MI:0016"(circular dichroism) Babenko et al. (2013) pubmed:23416304|mint:MINT-8413634|mint:d-12-02034r1 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8438053|mint:MINT-8413664 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-52901N|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0009306"(protein secretion)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032094"(response to food)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035938"(estradiol secretion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1903431"(positive regulation of cell maturation)|go:"GO:1903488"(negative regulation of lactation)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1903524"(positive regulation of blood circulation)|go:"GO:1903544"(response to butyrate)|go:"GO:1903576"(response to L-arginine)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|rcsb pdb:1APH|rcsb pdb:1BPH|rcsb pdb:1CPH|rcsb pdb:1DPH|rcsb pdb:1HO0|rcsb pdb:1PID|rcsb pdb:2A3G|rcsb pdb:2BN1|rcsb pdb:2BN3|rcsb pdb:2INS|rcsb pdb:2ZP6|rcsb pdb:4BS3|rcsb pdb:4E7T|rcsb pdb:4E7U|rcsb pdb:4E7V|rcsb pdb:4I5Y|rcsb pdb:4I5Z|rcsb pdb:4IDW|rcsb pdb:4IHN|rcsb pdb:4M4F|rcsb pdb:4M4H|rcsb pdb:4M4I|rcsb pdb:4M4J|rcsb pdb:4M4L|rcsb pdb:4M4M|rcsb pdb:5AZZ|rcsb pdb:5KQV|rcsb pdb:5MIZ|rcsb pdb:6KH9|rcsb pdb:6KHA|rcsb pdb:6OR0|rcsb pdb:6Q8Q|rcsb pdb:6QQ7|rcsb pdb:6QQG|rcsb pdb:6QRH|rcsb pdb:6QRK|rcsb pdb:6ZHB|rcsb pdb:6ZI8|rcsb pdb:7ELJ|rcsb pdb:6KH8|mint:MINT-8413668(identity) dip:DIP-52901N|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0009306"(protein secretion)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032094"(response to food)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035938"(estradiol secretion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1903431"(positive regulation of cell maturation)|go:"GO:1903488"(negative regulation of lactation)|go:"GO:1903489"(positive regulation of lactation)|go:"GO:1903524"(positive regulation of blood circulation)|go:"GO:1903544"(response to butyrate)|go:"GO:1903576"(response to L-arginine)|interpro:IPR004825(Insulin/IGF/relaxin)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|rcsb pdb:1APH|rcsb pdb:1BPH|rcsb pdb:1CPH|rcsb pdb:1DPH|rcsb pdb:1HO0|rcsb pdb:1PID|rcsb pdb:2A3G|rcsb pdb:2BN1|rcsb pdb:2BN3|rcsb pdb:2INS|rcsb pdb:2ZP6|rcsb pdb:4BS3|rcsb pdb:4E7T|rcsb pdb:4E7U|rcsb pdb:4E7V|rcsb pdb:4I5Y|rcsb pdb:4I5Z|rcsb pdb:4IDW|rcsb pdb:4IHN|rcsb pdb:4M4F|rcsb pdb:4M4H|rcsb pdb:4M4I|rcsb pdb:4M4J|rcsb pdb:4M4L|rcsb pdb:4M4M|rcsb pdb:5AZZ|rcsb pdb:5KQV|rcsb pdb:5MIZ|rcsb pdb:6KH9|rcsb pdb:6KHA|rcsb pdb:6OR0|rcsb pdb:6Q8Q|rcsb pdb:6QQ7|rcsb pdb:6QQG|rcsb pdb:6QRH|rcsb pdb:6QRK|rcsb pdb:6ZHB|rcsb pdb:6ZI8|rcsb pdb:7ELJ|rcsb pdb:6KH8|mint:MINT-8413666(identity) - - - comment:mint|figure legend:f2f f3 taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/06 2014/10/16 rogid:CgQ4BPd2mlhYt73TJXbE6V9GJYs9913 rogid:CgQ4BPd2mlhYt73TJXbE6V9GJYs9913 intact-crc:BA07BBBEFCFAC1D4|rigid:hUyIEGMcFAdui5udi+emCJNQyNc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00698 uniprotkb:P00698 intact:EBI-1029543|uniprotkb:Q90884|ensembl:ENSGALP00000016177|uniprotkb:B8YJN9|uniprotkb:B8YJP1|uniprotkb:B8YJT7|uniprotkb:B8YK79 intact:EBI-1029543|uniprotkb:Q90884|ensembl:ENSGALP00000016177|uniprotkb:B8YJN9|uniprotkb:B8YJP1|uniprotkb:B8YJT7|uniprotkb:B8YK79 psi-mi:lysc_chick(display_long)|uniprotkb:LYZ(gene name)|psi-mi:LYZ(display_short)|uniprotkb:1,4-beta-N-acetylmuramidase C(gene name synonym)|uniprotkb:Allergen Gal d IV(gene name synonym) psi-mi:lysc_chick(display_long)|uniprotkb:LYZ(gene name)|psi-mi:LYZ(display_short)|uniprotkb:1,4-beta-N-acetylmuramidase C(gene name synonym)|uniprotkb:Allergen Gal d IV(gene name synonym) psi-mi:"MI:0016"(circular dichroism) Babenko et al. (2013) pubmed:23416304|mint:MINT-8413634|mint:d-12-02034r1 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8438104|mint:MINT-8413701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:1BGI|rcsb pdb:1BHZ|rcsb pdb:1BVK|rcsb pdb:1BVX|rcsb pdb:1BWH|rcsb pdb:1BWI|rcsb pdb:1BWJ|rcsb pdb:1C08|rcsb pdb:1C10|rcsb pdb:1DPW|rcsb pdb:1DPX|rcsb pdb:1DQJ|rcsb pdb:1E8L|rcsb pdb:1F0W|rcsb pdb:1F10|rcsb pdb:1F3J|rcsb pdb:1FDL|rcsb pdb:1FLQ|rcsb pdb:1FLU|rcsb pdb:1FLW|rcsb pdb:1FLY|rcsb pdb:1FN5|rcsb pdb:1G7H|rcsb pdb:1G7I|rcsb pdb:1B2K|rcsb pdb:1G7J|rcsb pdb:1G7L|rcsb pdb:1G7M|rcsb pdb:1GPQ|rcsb pdb:1GWD|rcsb pdb:1GXV|rcsb pdb:1GXX|rcsb pdb:1H6M|rcsb pdb:1JIY|rcsb pdb:1JJ0|rcsb pdb:1JJ1|rcsb pdb:1JJ3|rcsb pdb:1JPO|rcsb pdb:1JTO|rcsb pdb:1JTT|rcsb pdb:1KIP|rcsb pdb:1KIQ|rcsb pdb:1KIR|rcsb pdb:1KXW|rcsb pdb:1KXX|rcsb pdb:1KXY|rcsb pdb:1LCN|rcsb pdb:1LJ3|rcsb pdb:1JIT|rcsb pdb:1LJ4|rcsb pdb:1LJE|rcsb pdb:1LJF|rcsb pdb:1LJG|rcsb pdb:1LJH|rcsb pdb:1LJI|rcsb pdb:1LJJ|rcsb pdb:1LJK|rcsb pdb:1LKR|rcsb pdb:1HC0|rcsb pdb:1HEL|rcsb pdb:1HEM|rcsb pdb:1HEN|rcsb pdb:1HEO|rcsb pdb:1HEP|rcsb pdb:1HEQ|rcsb pdb:1HER|rcsb pdb:1HEW|rcsb pdb:1HF4|rcsb pdb:1HSW|rcsb pdb:1HSX|rcsb pdb:1IC4|rcsb pdb:1IC5|rcsb pdb:1IC7|rcsb pdb:1IEE|rcsb pdb:1IO5|rcsb pdb:1IOQ|rcsb pdb:1IOR|rcsb pdb:1IOS|rcsb pdb:1IOT|rcsb pdb:1IR7|rcsb pdb:1IR8|rcsb pdb:1IR9|rcsb pdb:1J1O|rcsb pdb:1J1P|rcsb pdb:1J1X|rcsb pdb:1JA2|rcsb pdb:1H87|rcsb pdb:1JA4|rcsb pdb:1JA6|rcsb pdb:1JA7|rcsb pdb:1JIS|ensembl:ENSGALT00000016196(transcript)|go:"GO:0003796"(lysozyme activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016231"(beta-N-acetylglucosaminidase activity)|go:"GO:0016998"(cell wall macromolecule catabolic process)|ensembl:ENSGALG00000009963(gene)|go:"GO:0019835"(cytolysis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051672"(obsolete catabolism by organism of cell wall peptidoglycan in other organism)|interpro:IPR000974(Glycoside hydrolase, family 22, lysozyme)|interpro:IPR001916(Glycoside hydrolase, family 22)|interpro:IPR019799|interpro:IPR023346|interpro:IPR030056|rcsb pdb:132L|rcsb pdb:193L|rcsb pdb:194L|rcsb pdb:1A2Y|rcsb pdb:1AKI|rcsb pdb:1AT5|rcsb pdb:1AT6|rcsb pdb:1AZF|rcsb pdb:1B0D|rcsb pdb:1UIF|rcsb pdb:1UIG|rcsb pdb:1UIH|rcsb pdb:1UUZ|rcsb pdb:1V7S|rcsb pdb:1V7T|rcsb pdb:1VAT|rcsb pdb:1VAU|rcsb pdb:1UIE|rcsb pdb:1VDP|rcsb pdb:1VDQ|rcsb pdb:1VDS|rcsb pdb:1VDT|rcsb pdb:1VED|rcsb pdb:1VFB|rcsb pdb:1W6Z|rcsb pdb:1WTM|rcsb pdb:1WTN|rcsb pdb:1XEI|rcsb pdb:1XEJ|rcsb pdb:1XEK|rcsb pdb:1XFP|rcsb pdb:1XGP|rcsb pdb:1XGQ|rcsb pdb:1XGR|rcsb pdb:1XGT|rcsb pdb:1XGU|rcsb pdb:1YIK|rcsb pdb:1YIL|rcsb pdb:1YKX|rcsb pdb:1YKY|rcsb pdb:1YKZ|rcsb pdb:1LMA|rcsb pdb:1LPI|rcsb pdb:1LSA|rcsb pdb:1LSB|rcsb pdb:1LSC|rcsb pdb:1LSD|rcsb pdb:1LSE|rcsb pdb:1LSF|rcsb pdb:1LSG|rcsb pdb:1LSM|rcsb pdb:1LSN|rcsb pdb:1LSY|rcsb pdb:1LSZ|rcsb pdb:1LYO|rcsb pdb:1LYS|rcsb pdb:1LYZ|rcsb pdb:1LZ8|rcsb pdb:1LKS|rcsb pdb:1LZ9|rcsb pdb:1LZA|rcsb pdb:1LZB|rcsb pdb:1LZC|rcsb pdb:1LZD|rcsb pdb:1UA6|rcsb pdb:1UC0|rcsb pdb:1UCO|rcsb pdb:1UIA|rcsb pdb:1UIB|rcsb pdb:1UIC|rcsb pdb:1LZE|rcsb pdb:1LZG|rcsb pdb:1LZH|rcsb pdb:1LZN|rcsb pdb:1LZT|rcsb pdb:1MEL|rcsb pdb:1MLC|rcsb pdb:1N4F|rcsb pdb:1NBY|rcsb pdb:1NBZ|rcsb pdb:1NDG|rcsb pdb:1NDM|rcsb pdb:1P2C|rcsb pdb:1PS5|rcsb pdb:1QIO|rcsb pdb:1QTK|rcsb pdb:1RCM|rcsb pdb:1RFP|rcsb pdb:1RI8|rcsb pdb:1RJC|rcsb pdb:1SF4|rcsb pdb:1SF6|rcsb pdb:1SF7|rcsb pdb:1SFB|rcsb pdb:1SFG|rcsb pdb:1SQ2|rcsb pdb:1T3P|rcsb pdb:1T6V|rcsb pdb:1UID|rcsb pdb:1YL1|rcsb pdb:1YQV|rcsb pdb:1Z55|rcsb pdb:1ZMY|rcsb pdb:1ZV5|rcsb pdb:1ZVH|rcsb pdb:1ZVY|rcsb pdb:2A6U|rcsb pdb:2A7D|rcsb pdb:2A7F|rcsb pdb:2AUB|rcsb pdb:2B5Z|rcsb pdb:2BLX|rcsb pdb:2BLY|rcsb pdb:2BPU|rcsb pdb:2C8O|rcsb pdb:2C8P|rcsb pdb:2CDS|rcsb pdb:2CGI|rcsb pdb:2D4I|rcsb pdb:1YL0|rcsb pdb:2D4J|rcsb pdb:2D4K|rcsb pdb:2D6B|rcsb pdb:2D91|rcsb pdb:2DQD|rcsb pdb:2DQE|rcsb pdb:2DQC|rcsb pdb:2DQF|rcsb pdb:2DQG|rcsb pdb:2DQH|rcsb pdb:2DQI|rcsb pdb:2DQJ|rcsb pdb:2EIZ|rcsb pdb:2EKS|rcsb pdb:2EPE|rcsb pdb:2F2N|rcsb pdb:2F30|rcsb pdb:2F4A|rcsb pdb:2F4G|rcsb pdb:2FBB|rcsb pdb:2G4P|rcsb pdb:2G4Q|rcsb pdb:2H9J|rcsb pdb:2H9K|rcsb pdb:2HFM|rcsb pdb:2HS7|rcsb pdb:2HS9|rcsb pdb:2HSO|rcsb pdb:2HTX|rcsb pdb:2HU1|rcsb pdb:2HU3|rcsb pdb:2HUB|rcsb pdb:2I25|rcsb pdb:2I26|rcsb pdb:2I6Z|rcsb pdb:2IFF|rcsb pdb:2LYM|rcsb pdb:2LYO|rcsb pdb:2LYZ|rcsb pdb:2LZH|rcsb pdb:2LZT|rcsb pdb:2PC2|rcsb pdb:2Q0M|rcsb pdb:2VB1|rcsb pdb:2W1L|rcsb pdb:2W1M|rcsb pdb:2W1X|rcsb pdb:2W1Y|rcsb pdb:2WAR|rcsb pdb:2X0A|rcsb pdb:2XBR|rcsb pdb:2XBS|rcsb pdb:2XJW|rcsb pdb:2XTH|rcsb pdb:2YBH|rcsb pdb:2YBI|rcsb pdb:2YBJ|rcsb pdb:2YBL|rcsb pdb:2YBM|rcsb pdb:2YDG|rcsb pdb:2YSS|rcsb pdb:2YVB|rcsb pdb:2Z12|rcsb pdb:2Z18|rcsb pdb:2Z19|rcsb pdb:2ZNW|rcsb pdb:2YBN|rcsb pdb:2ZNX|rcsb pdb:2ZQ3|rcsb pdb:2ZYP|rcsb pdb:3A34|rcsb pdb:3A3Q|rcsb pdb:3A3R|rcsb pdb:3A67|rcsb pdb:3A6B|rcsb pdb:3A6C|rcsb pdb:3A8Z|rcsb pdb:3A90|rcsb pdb:3A91|rcsb pdb:3A92|rcsb pdb:3A93|rcsb pdb:3A94|rcsb pdb:3A95|rcsb pdb:3A96|rcsb pdb:3AGG|rcsb pdb:3AGH|rcsb pdb:3AGI|rcsb pdb:3AJN|rcsb pdb:3ATN|rcsb pdb:3ATO|rcsb pdb:3AW6|rcsb pdb:3AW7|rcsb pdb:3AZ4|rcsb pdb:3AZ5|rcsb pdb:3AZ6|rcsb pdb:3AZ7|rcsb pdb:3B6L|rcsb pdb:3B72|rcsb pdb:3D9A|rcsb pdb:3E3D|rcsb pdb:3EMS|rcsb pdb:3EXD|rcsb pdb:3F6Z|rcsb pdb:3G3A|rcsb pdb:3G3B|rcsb pdb:3HFM|rcsb pdb:3IJU|rcsb pdb:2ZQ4|rcsb pdb:3IJV|rcsb pdb:3J4G|rcsb pdb:3J6K|rcsb pdb:3KAM|rcsb pdb:3LYT|rcsb pdb:3LYZ|rcsb pdb:3LZT|rcsb pdb:3M18|rcsb pdb:3M3U|rcsb pdb:3MBE|rcsb pdb:3N9A|rcsb pdb:3N9C|rcsb pdb:3N9E|rcsb pdb:3OJP|rcsb pdb:3OK0|rcsb pdb:3OTP|rcsb pdb:3P4Z|rcsb pdb:3P64|rcsb pdb:3P65|rcsb pdb:3P66|rcsb pdb:3P68|rcsb pdb:3QE8|rcsb pdb:3QNG|rcsb pdb:3QY4|rcsb pdb:3LYO|rcsb pdb:3RNX|rcsb pdb:3RT5|rcsb pdb:3LYM|rcsb pdb:3WU7|rcsb pdb:3WU8|rcsb pdb:3WU9|rcsb pdb:4B49|rcsb pdb:3WUA|rcsb pdb:3WUL|rcsb pdb:3WUM|rcsb pdb:3WUN|rcsb pdb:4B4E|rcsb pdb:3WVX|rcsb pdb:3WVY|rcsb pdb:3WW5|rcsb pdb:3WW6|rcsb pdb:3WXT|rcsb pdb:3WXU|rcsb pdb:3ZEK|rcsb pdb:3ZVQ|rcsb pdb:4A7D|rcsb pdb:4A8A|rcsb pdb:4A8B|rcsb pdb:4AGA|rcsb pdb:4AXT|rcsb pdb:4B0D|rcsb pdb:4B1A|rcsb pdb:3RW8|rcsb pdb:3RZ4|rcsb pdb:3SP3|rcsb pdb:3T6U|rcsb pdb:3TMU|rcsb pdb:3TMV|rcsb pdb:3TMW|rcsb pdb:3TMX|rcsb pdb:3TXB|rcsb pdb:3TXD|rcsb pdb:3TXE|rcsb pdb:3TXF|rcsb pdb:3TXG|rcsb pdb:3TXH|rcsb pdb:3TXI|rcsb pdb:3TXJ|rcsb pdb:3TXK|rcsb pdb:3ULR|rcsb pdb:3W6A|rcsb pdb:3WL2|rcsb pdb:3WMK|rcsb pdb:3RU5|rcsb pdb:3WPJ|rcsb pdb:3WPK|rcsb pdb:3WPL|rcsb pdb:4DDC|rcsb pdb:4DT3|rcsb pdb:4E3U|rcsb pdb:4BAD|rcsb pdb:4BAF|rcsb pdb:4BAP|rcsb pdb:4BS7|rcsb pdb:4C3W|rcsb pdb:4CJ2|rcsb pdb:4D9Z|rcsb pdb:4DC4|rcsb pdb:4DD0|rcsb pdb:4DD1|rcsb pdb:4DD2|rcsb pdb:4DD3|rcsb pdb:4DD7|rcsb pdb:4DD9|rcsb pdb:4DDA|rcsb pdb:4DDB|rcsb pdb:4EOF|rcsb pdb:4B4I|rcsb pdb:4B4J|rcsb pdb:4FJR|rcsb pdb:4G49|rcsb pdb:4G4B|rcsb pdb:4G4C|rcsb pdb:4G4H|rcsb pdb:4GCB|rcsb pdb:4GCC|rcsb pdb:4GCD|rcsb pdb:4GCE|rcsb pdb:4GCF|rcsb pdb:4GLA|rcsb pdb:4GLV|rcsb pdb:4GN3|rcsb pdb:4GN4|rcsb pdb:4GN5|rcsb pdb:4H1P|rcsb pdb:4H8X|rcsb pdb:4H8Y|rcsb pdb:4H8Z|rcsb pdb:4H90|rcsb pdb:4H91|rcsb pdb:4ETE|rcsb pdb:4H92|rcsb pdb:4H93|rcsb pdb:4H94|rcsb pdb:4H9A|rcsb pdb:4ET9|rcsb pdb:4ETA|rcsb pdb:4ETB|rcsb pdb:4ETC|rcsb pdb:4ETD|rcsb pdb:4ET8|rcsb pdb:4H9B|rcsb pdb:4H9C|rcsb pdb:4H9E|rcsb pdb:4H9F|rcsb pdb:4H9H|rcsb pdb:4H9I|rcsb pdb:4HP0|rcsb pdb:4HPI|rcsb pdb:4HSF|rcsb pdb:4HTK|rcsb pdb:4HTN|rcsb pdb:4HTQ|rcsb pdb:4HV1|rcsb pdb:4HV2|rcsb pdb:4I8S|rcsb pdb:4IAS|rcsb pdb:4IAT|rcsb pdb:4II8|rcsb pdb:4J1A|rcsb pdb:4J1B|rcsb pdb:4J7V|rcsb pdb:4KXI|rcsb pdb:4LFP|rcsb pdb:4PPO|rcsb pdb:4LFX|rcsb pdb:4LGK|rcsb pdb:4LT0|rcsb pdb:4LT1|rcsb pdb:4LT2|rcsb pdb:4LT3|rcsb pdb:4LYB|rcsb pdb:4LYC|rcsb pdb:4LYM|rcsb pdb:4LYO|rcsb pdb:4LYT|rcsb pdb:4LYZ|rcsb pdb:4LZT|rcsb pdb:4M4O|rcsb pdb:4M6D|rcsb pdb:4MR1|rcsb pdb:4N0J|rcsb pdb:4N1C|rcsb pdb:4N1E|rcsb pdb:4N5R|rcsb pdb:4N8Z|rcsb pdb:4N9R|rcsb pdb:4NEB|rcsb pdb:4NFV|rcsb pdb:4NG1|rcsb pdb:4NG8|rcsb pdb:4NGI|rcsb pdb:4NGJ|rcsb pdb:4NGL|rcsb pdb:4NGO|rcsb pdb:4NGV|rcsb pdb:4NGW|rcsb pdb:4NGY|rcsb pdb:4NGZ|rcsb pdb:4NHI|rcsb pdb:4NHP|rcsb pdb:4NHQ|rcsb pdb:4NHS|rcsb pdb:4NHT|rcsb pdb:4NGK|rcsb pdb:4NIJ|rcsb pdb:4NSG|rcsb pdb:4NSH|rcsb pdb:4NSI|rcsb pdb:4NSJ|rcsb pdb:4NWE|rcsb pdb:4NWH|rcsb pdb:4NY5|rcsb pdb:4O34|rcsb pdb:4OOO|rcsb pdb:4OOT|rcsb pdb:4OWA|rcsb pdb:4OWB|rcsb pdb:4OWC|rcsb pdb:4OWE|rcsb pdb:4OWH|rcsb pdb:4P2E|rcsb pdb:4PGJ|rcsb pdb:4PHI|rcsb pdb:4WG7|rcsb pdb:4WL6|rcsb pdb:4WL7|rcsb pdb:4WLD|rcsb pdb:4WLT|rcsb pdb:4WLX|rcsb pdb:4WLY|rcsb pdb:4WM1|rcsb pdb:4WM2|rcsb pdb:4WM3|rcsb pdb:4WM4|rcsb pdb:4WM5|rcsb pdb:4WM6|rcsb pdb:4PRU|rcsb pdb:4QEQ|rcsb pdb:4QGZ|rcsb pdb:4QY9|rcsb pdb:4R0F|rcsb pdb:4R6C|rcsb pdb:4RDS|rcsb pdb:4RLM|rcsb pdb:4RLN|rcsb pdb:4RW1|rcsb pdb:4RW2|rcsb pdb:4TSA|rcsb pdb:4TSB|rcsb pdb:4TSC|rcsb pdb:4TTD|rcsb pdb:4PRQ|rcsb pdb:4TUN|rcsb pdb:4TWS|rcsb pdb:4U3X|rcsb pdb:4UWN|rcsb pdb:4UWU|rcsb pdb:4UWV|rcsb pdb:4W94|rcsb pdb:4W96|rcsb pdb:4WG1|rcsb pdb:4WMG|rcsb pdb:4WO6|rcsb pdb:4WO9|rcsb pdb:4WOA|rcsb pdb:4X3B|rcsb pdb:4XAD|rcsb pdb:4XEN|rcsb pdb:4XJB|rcsb pdb:4XJD|rcsb pdb:4XJF|rcsb pdb:4XJG|rcsb pdb:4XJH|rcsb pdb:4XJI|rcsb pdb:4XN6|rcsb pdb:4XYY|rcsb pdb:4YEM|rcsb pdb:4YEN|rcsb pdb:4YEO|rcsb pdb:4YM8|rcsb pdb:4YOP|rcsb pdb:4Z3M|rcsb pdb:4Z41|rcsb pdb:4Z46|rcsb pdb:4Z98|rcsb pdb:4ZEE|rcsb pdb:4ZFP|rcsb pdb:4ZIX|rcsb pdb:5C6L|rcsb pdb:5D5C|rcsb pdb:5D5F|rcsb pdb:5A3E|rcsb pdb:5DL9|rcsb pdb:5DLA|rcsb pdb:5A3Z|rcsb pdb:5AMY|rcsb pdb:5APC|rcsb pdb:5APD|rcsb pdb:5APE|rcsb pdb:5DM9|rcsb pdb:5E4P|rcsb pdb:5E9R|rcsb pdb:5EBH|rcsb pdb:5F14|rcsb pdb:5F16|rcsb pdb:5F81|rcsb pdb:5F9U|rcsb pdb:5F9X|rcsb pdb:5APF|rcsb pdb:5B05|rcsb pdb:5B06|rcsb pdb:5B07|rcsb pdb:5B1F|rcsb pdb:5B1G|rcsb pdb:5B59|rcsb pdb:5FCP|rcsb pdb:5FDJ|rcsb pdb:5FEK|rcsb pdb:5FEL|rcsb pdb:5FHW|rcsb pdb:5FST|rcsb pdb:5GWB|rcsb pdb:5HLL|rcsb pdb:5HMJ|rcsb pdb:5HMV|rcsb pdb:5HNC|rcsb pdb:5HNL|rcsb pdb:5HQ1|rcsb pdb:5I4W|rcsb pdb:5I4X|rcsb pdb:5I4Y|rcsb pdb:5I53|rcsb pdb:5I54|rcsb pdb:5I5Q|rcsb pdb:5IDD|rcsb pdb:5IEL|rcsb pdb:5IHG|rcsb pdb:5II3|rcsb pdb:5ILC|rcsb pdb:5ILF|rcsb pdb:5J7C|rcsb pdb:5B5J|rcsb pdb:5C6I|rcsb pdb:5C6J|rcsb pdb:5JEN|rcsb pdb:5K2K|rcsb pdb:5K2N|rcsb pdb:6SIK|rcsb pdb:5NJP|rcsb pdb:5NJQ|rcsb pdb:5NJR|rcsb pdb:5NJS|rcsb pdb:5O4W|rcsb pdb:5O4X|rcsb pdb:5O6Q|rcsb pdb:5OB6|rcsb pdb:5OB7|rcsb pdb:5OB8|rcsb pdb:5OB9|rcsb pdb:5OCV|rcsb pdb:5OER|rcsb pdb:5OLE|rcsb pdb:5NJM|rcsb pdb:5OOV|rcsb pdb:5OOY|rcsb pdb:5OP1|rcsb pdb:5T3F|rcsb pdb:5TK0|rcsb pdb:5UVJ|rcsb pdb:5V4G|rcsb pdb:5V4H|rcsb pdb:5V4I|rcsb pdb:5WR9|rcsb pdb:5WRA|rcsb pdb:5WRB|rcsb pdb:5YIN|rcsb pdb:5YKY|rcsb pdb:6A10|rcsb pdb:6A4N|rcsb pdb:6A4O|rcsb pdb:6A4P|rcsb pdb:6A4Q|rcsb pdb:6ABN|rcsb pdb:6ABZ|rcsb pdb:6AC2|rcsb pdb:6AD5|rcsb pdb:6ADF|rcsb pdb:6AEA|rcsb pdb:6AGN|rcsb pdb:6AGR|rcsb pdb:6AHH|rcsb pdb:6AHL|rcsb pdb:6APM|rcsb pdb:6B7U|rcsb pdb:6B7V|rcsb pdb:6B7W|rcsb pdb:6BO1|rcsb pdb:6BO2|rcsb pdb:6BRE|rcsb pdb:6CIW|rcsb pdb:6D6E|rcsb pdb:6D6F|rcsb pdb:6D6G|rcsb pdb:6D6H|rcsb pdb:6F1L|rcsb pdb:6F1M|rcsb pdb:6F1O|rcsb pdb:6F1P|rcsb pdb:6F1R|rcsb pdb:6F2I|rcsb pdb:6F2J|rcsb pdb:6F2K|rcsb pdb:6F9X|rcsb pdb:6F9Y|rcsb pdb:6F9Z|rcsb pdb:6FA0|rcsb pdb:5K2P|rcsb pdb:5K2Q|rcsb pdb:5K2R|rcsb pdb:5K2S|rcsb pdb:5K7O|rcsb pdb:5KJ9|rcsb pdb:5KKI|rcsb pdb:5KKJ|rcsb pdb:5KXK|rcsb pdb:5KXL|rcsb pdb:5KXM|rcsb pdb:5KXN|rcsb pdb:5KXO|rcsb pdb:5KXP|rcsb pdb:5KXR|rcsb pdb:5KXS|rcsb pdb:5KXT|rcsb pdb:5KXW|rcsb pdb:5KXX|rcsb pdb:5KXY|rcsb pdb:5KXZ|rcsb pdb:5KY1|rcsb pdb:5L3H|rcsb pdb:5L3I|rcsb pdb:5L9J|rcsb pdb:5LA5|rcsb pdb:6FRO|rcsb pdb:5LA8|rcsb pdb:5LAF|rcsb pdb:5LAG|rcsb pdb:5LAN|rcsb pdb:5LIN|rcsb pdb:5LIO|rcsb pdb:5LVG|rcsb pdb:5LVH|rcsb pdb:5LVI|rcsb pdb:5LVJ|rcsb pdb:5LXW|rcsb pdb:5LYM|rcsb pdb:5LYT|rcsb pdb:5LYZ|rcsb pdb:5M1Y|rcsb pdb:5MJJ|rcsb pdb:5MYY|rcsb pdb:5NBJ|rcsb pdb:5NE0|rcsb pdb:5NJ1|rcsb pdb:6FRQ|rcsb pdb:6FSJ|rcsb pdb:6FTR|rcsb pdb:6G5C|rcsb pdb:6G5V|rcsb pdb:6G5Y|rcsb pdb:6G8A|rcsb pdb:6GF0|rcsb pdb:6GNL|rcsb pdb:6GOB|rcsb pdb:6GOH|rcsb pdb:6GOI|rcsb pdb:6GOJ|rcsb pdb:6H0K|rcsb pdb:6H0L|rcsb pdb:6H3B|rcsb pdb:6H79|rcsb pdb:6HT2|rcsb pdb:6HU5|rcsb pdb:6HY4|rcsb pdb:6HY6|rcsb pdb:6HY8|rcsb pdb:6HYB|rcsb pdb:6IG6|rcsb pdb:6IRJ|rcsb pdb:6JB2|rcsb pdb:6JB5|rcsb pdb:6JB8|rcsb pdb:6JXP|rcsb pdb:6JXQ|rcsb pdb:6JZI|rcsb pdb:6K5Q|rcsb pdb:6K8G|rcsb pdb:6KCB|rcsb pdb:6KCD|rcsb pdb:6KD1|rcsb pdb:6LAV|rcsb pdb:6LL3|rcsb pdb:6LT5|rcsb pdb:6LYT|rcsb pdb:6LYZ|rcsb pdb:6MQV|rcsb pdb:6MUZ|rcsb pdb:6MX9|rcsb pdb:6O2H|rcsb pdb:6P4A|rcsb pdb:6P4B|rcsb pdb:6P4D|rcsb pdb:6PBB|rcsb pdb:6PL9|rcsb pdb:6PLA|rcsb pdb:6PLB|rcsb pdb:6Q88|rcsb pdb:6Q8R|rcsb pdb:6Q8T|rcsb pdb:6QEA|rcsb pdb:6QNB|rcsb pdb:6QQ3|rcsb pdb:6QQC|rcsb pdb:6QQD|rcsb pdb:6QQE|rcsb pdb:6QQF|rcsb pdb:6QWW|rcsb pdb:6QWX|rcsb pdb:6QWY|rcsb pdb:6QWZ|rcsb pdb:6QX0|rcsb pdb:6QXW|rcsb pdb:6QXX|rcsb pdb:6QXY|rcsb pdb:6QY0|rcsb pdb:6QY1|rcsb pdb:6QY2|rcsb pdb:6QY4|rcsb pdb:6QY5|rcsb pdb:6RNB|rcsb pdb:6RNC|rcsb pdb:6RO3|rcsb pdb:6RO5|rcsb pdb:6RT1|rcsb pdb:6RT3|rcsb pdb:6RT9|rcsb pdb:6RTA|rcsb pdb:6RXI|rcsb pdb:6S2N|rcsb pdb:6S7N|rcsb pdb:6SET|rcsb pdb:6SEU|rcsb pdb:6SEW|rcsb pdb:6SEX|rcsb pdb:6SEZ|rcsb pdb:6SIJ|rcsb pdb:6SIL|rcsb pdb:6SIM|rcsb pdb:6SR0|rcsb pdb:6SR1|rcsb pdb:6SR2|rcsb pdb:6SR3|rcsb pdb:6SR4|rcsb pdb:6SR5|rcsb pdb:6SYC|rcsb pdb:6SYD|rcsb pdb:6SYE|rcsb pdb:6TVL|rcsb pdb:6TVY|rcsb pdb:6W7P|rcsb pdb:6W8E|rcsb pdb:6WRL|rcsb pdb:6WRM|rcsb pdb:6WX5|rcsb pdb:6YBF|rcsb pdb:6YBI|rcsb pdb:6YJX|rcsb pdb:6YOB|rcsb pdb:6YOC|rcsb pdb:6YOD|rcsb pdb:6YOE|rcsb pdb:6ZS8|rcsb pdb:7A70|rcsb pdb:7BE2|rcsb pdb:7BEB|rcsb pdb:7BEC|rcsb pdb:7BR5|rcsb pdb:7BVM|rcsb pdb:7BVO|rcsb pdb:7BYO|rcsb pdb:7BYP|rcsb pdb:7C09|rcsb pdb:7AVE|rcsb pdb:7AVF|rcsb pdb:7AVG|rcsb pdb:7BDZ|rcsb pdb:7BE0|rcsb pdb:7BE1|rcsb pdb:7CDK|rcsb pdb:7CDM|rcsb pdb:7CDN|rcsb pdb:7CDO|rcsb pdb:7CDP|rcsb pdb:7CDQ|rcsb pdb:7CDR|rcsb pdb:7CDS|rcsb pdb:7CDT|rcsb pdb:7CDU|rcsb pdb:7CJZ|rcsb pdb:7DEQ|rcsb pdb:7DER|rcsb pdb:7DTB|rcsb pdb:7DTF|rcsb pdb:7E02|rcsb pdb:7JMU|rcsb pdb:7KH5|rcsb pdb:7L84|rcsb pdb:7LYZ|rcsb pdb:7NJF|rcsb pdb:7NKF|rcsb pdb:8LYZ|rcsb pdb:9LYZ|reactome:R-GGA-6798695|reactome:R-GGA-6803157|rcsb pdb:7CVJ|rcsb pdb:7CVL|rcsb pdb:7D01|rcsb pdb:7D02|rcsb pdb:7D04|rcsb pdb:7D05|rcsb pdb:7D0W|refseq:NP_990612.1|dip:DIP-46258N|mint:MINT-8413705(identity) rcsb pdb:1BGI|rcsb pdb:1BHZ|rcsb pdb:1BVK|rcsb pdb:1BVX|rcsb pdb:1BWH|rcsb pdb:1BWI|rcsb pdb:1BWJ|rcsb pdb:1C08|rcsb pdb:1C10|rcsb pdb:1DPW|rcsb pdb:1DPX|rcsb pdb:1DQJ|rcsb pdb:1E8L|rcsb pdb:1F0W|rcsb pdb:1F10|rcsb pdb:1F3J|rcsb pdb:1FDL|rcsb pdb:1FLQ|rcsb pdb:1FLU|rcsb pdb:1FLW|rcsb pdb:1FLY|rcsb pdb:1FN5|rcsb pdb:1G7H|rcsb pdb:1G7I|rcsb pdb:1B2K|rcsb pdb:1G7J|rcsb pdb:1G7L|rcsb pdb:1G7M|rcsb pdb:1GPQ|rcsb pdb:1GWD|rcsb pdb:1GXV|rcsb pdb:1GXX|rcsb pdb:1H6M|rcsb pdb:1JIY|rcsb pdb:1JJ0|rcsb pdb:1JJ1|rcsb pdb:1JJ3|rcsb pdb:1JPO|rcsb pdb:1JTO|rcsb pdb:1JTT|rcsb pdb:1KIP|rcsb pdb:1KIQ|rcsb pdb:1KIR|rcsb pdb:1KXW|rcsb pdb:1KXX|rcsb pdb:1KXY|rcsb pdb:1LCN|rcsb pdb:1LJ3|rcsb pdb:1JIT|rcsb pdb:1LJ4|rcsb pdb:1LJE|rcsb pdb:1LJF|rcsb pdb:1LJG|rcsb pdb:1LJH|rcsb pdb:1LJI|rcsb pdb:1LJJ|rcsb pdb:1LJK|rcsb pdb:1LKR|rcsb pdb:1HC0|rcsb pdb:1HEL|rcsb pdb:1HEM|rcsb pdb:1HEN|rcsb pdb:1HEO|rcsb pdb:1HEP|rcsb pdb:1HEQ|rcsb pdb:1HER|rcsb pdb:1HEW|rcsb pdb:1HF4|rcsb pdb:1HSW|rcsb pdb:1HSX|rcsb pdb:1IC4|rcsb pdb:1IC5|rcsb pdb:1IC7|rcsb pdb:1IEE|rcsb pdb:1IO5|rcsb pdb:1IOQ|rcsb pdb:1IOR|rcsb pdb:1IOS|rcsb pdb:1IOT|rcsb pdb:1IR7|rcsb pdb:1IR8|rcsb pdb:1IR9|rcsb pdb:1J1O|rcsb pdb:1J1P|rcsb pdb:1J1X|rcsb pdb:1JA2|rcsb pdb:1H87|rcsb pdb:1JA4|rcsb pdb:1JA6|rcsb pdb:1JA7|rcsb pdb:1JIS|ensembl:ENSGALT00000016196(transcript)|go:"GO:0003796"(lysozyme activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016231"(beta-N-acetylglucosaminidase activity)|go:"GO:0016998"(cell wall macromolecule catabolic process)|ensembl:ENSGALG00000009963(gene)|go:"GO:0019835"(cytolysis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051672"(obsolete catabolism by organism of cell wall peptidoglycan in other organism)|interpro:IPR000974(Glycoside hydrolase, family 22, lysozyme)|interpro:IPR001916(Glycoside hydrolase, family 22)|interpro:IPR019799|interpro:IPR023346|interpro:IPR030056|rcsb pdb:132L|rcsb pdb:193L|rcsb pdb:194L|rcsb pdb:1A2Y|rcsb pdb:1AKI|rcsb pdb:1AT5|rcsb pdb:1AT6|rcsb pdb:1AZF|rcsb pdb:1B0D|rcsb pdb:1UIF|rcsb pdb:1UIG|rcsb pdb:1UIH|rcsb pdb:1UUZ|rcsb pdb:1V7S|rcsb pdb:1V7T|rcsb pdb:1VAT|rcsb pdb:1VAU|rcsb pdb:1UIE|rcsb pdb:1VDP|rcsb pdb:1VDQ|rcsb pdb:1VDS|rcsb pdb:1VDT|rcsb pdb:1VED|rcsb pdb:1VFB|rcsb pdb:1W6Z|rcsb pdb:1WTM|rcsb pdb:1WTN|rcsb pdb:1XEI|rcsb pdb:1XEJ|rcsb pdb:1XEK|rcsb pdb:1XFP|rcsb pdb:1XGP|rcsb pdb:1XGQ|rcsb pdb:1XGR|rcsb pdb:1XGT|rcsb pdb:1XGU|rcsb pdb:1YIK|rcsb pdb:1YIL|rcsb pdb:1YKX|rcsb pdb:1YKY|rcsb pdb:1YKZ|rcsb pdb:1LMA|rcsb pdb:1LPI|rcsb pdb:1LSA|rcsb pdb:1LSB|rcsb pdb:1LSC|rcsb pdb:1LSD|rcsb pdb:1LSE|rcsb pdb:1LSF|rcsb pdb:1LSG|rcsb pdb:1LSM|rcsb pdb:1LSN|rcsb pdb:1LSY|rcsb pdb:1LSZ|rcsb pdb:1LYO|rcsb pdb:1LYS|rcsb pdb:1LYZ|rcsb pdb:1LZ8|rcsb pdb:1LKS|rcsb pdb:1LZ9|rcsb pdb:1LZA|rcsb pdb:1LZB|rcsb pdb:1LZC|rcsb pdb:1LZD|rcsb pdb:1UA6|rcsb pdb:1UC0|rcsb pdb:1UCO|rcsb pdb:1UIA|rcsb pdb:1UIB|rcsb pdb:1UIC|rcsb pdb:1LZE|rcsb pdb:1LZG|rcsb pdb:1LZH|rcsb pdb:1LZN|rcsb pdb:1LZT|rcsb pdb:1MEL|rcsb pdb:1MLC|rcsb pdb:1N4F|rcsb pdb:1NBY|rcsb pdb:1NBZ|rcsb pdb:1NDG|rcsb pdb:1NDM|rcsb pdb:1P2C|rcsb pdb:1PS5|rcsb pdb:1QIO|rcsb pdb:1QTK|rcsb pdb:1RCM|rcsb pdb:1RFP|rcsb pdb:1RI8|rcsb pdb:1RJC|rcsb pdb:1SF4|rcsb pdb:1SF6|rcsb pdb:1SF7|rcsb pdb:1SFB|rcsb pdb:1SFG|rcsb pdb:1SQ2|rcsb pdb:1T3P|rcsb pdb:1T6V|rcsb pdb:1UID|rcsb pdb:1YL1|rcsb pdb:1YQV|rcsb pdb:1Z55|rcsb pdb:1ZMY|rcsb pdb:1ZV5|rcsb pdb:1ZVH|rcsb pdb:1ZVY|rcsb pdb:2A6U|rcsb pdb:2A7D|rcsb pdb:2A7F|rcsb pdb:2AUB|rcsb pdb:2B5Z|rcsb pdb:2BLX|rcsb pdb:2BLY|rcsb pdb:2BPU|rcsb pdb:2C8O|rcsb pdb:2C8P|rcsb pdb:2CDS|rcsb pdb:2CGI|rcsb pdb:2D4I|rcsb pdb:1YL0|rcsb pdb:2D4J|rcsb pdb:2D4K|rcsb pdb:2D6B|rcsb pdb:2D91|rcsb pdb:2DQD|rcsb pdb:2DQE|rcsb pdb:2DQC|rcsb pdb:2DQF|rcsb pdb:2DQG|rcsb pdb:2DQH|rcsb pdb:2DQI|rcsb pdb:2DQJ|rcsb pdb:2EIZ|rcsb pdb:2EKS|rcsb pdb:2EPE|rcsb pdb:2F2N|rcsb pdb:2F30|rcsb pdb:2F4A|rcsb pdb:2F4G|rcsb pdb:2FBB|rcsb pdb:2G4P|rcsb pdb:2G4Q|rcsb pdb:2H9J|rcsb pdb:2H9K|rcsb pdb:2HFM|rcsb pdb:2HS7|rcsb pdb:2HS9|rcsb pdb:2HSO|rcsb pdb:2HTX|rcsb pdb:2HU1|rcsb pdb:2HU3|rcsb pdb:2HUB|rcsb pdb:2I25|rcsb pdb:2I26|rcsb pdb:2I6Z|rcsb pdb:2IFF|rcsb pdb:2LYM|rcsb pdb:2LYO|rcsb pdb:2LYZ|rcsb pdb:2LZH|rcsb pdb:2LZT|rcsb pdb:2PC2|rcsb pdb:2Q0M|rcsb pdb:2VB1|rcsb pdb:2W1L|rcsb pdb:2W1M|rcsb pdb:2W1X|rcsb pdb:2W1Y|rcsb pdb:2WAR|rcsb pdb:2X0A|rcsb pdb:2XBR|rcsb pdb:2XBS|rcsb pdb:2XJW|rcsb pdb:2XTH|rcsb pdb:2YBH|rcsb pdb:2YBI|rcsb pdb:2YBJ|rcsb pdb:2YBL|rcsb pdb:2YBM|rcsb pdb:2YDG|rcsb pdb:2YSS|rcsb pdb:2YVB|rcsb pdb:2Z12|rcsb pdb:2Z18|rcsb pdb:2Z19|rcsb pdb:2ZNW|rcsb pdb:2YBN|rcsb pdb:2ZNX|rcsb pdb:2ZQ3|rcsb pdb:2ZYP|rcsb pdb:3A34|rcsb pdb:3A3Q|rcsb pdb:3A3R|rcsb pdb:3A67|rcsb pdb:3A6B|rcsb pdb:3A6C|rcsb pdb:3A8Z|rcsb pdb:3A90|rcsb pdb:3A91|rcsb pdb:3A92|rcsb pdb:3A93|rcsb pdb:3A94|rcsb pdb:3A95|rcsb pdb:3A96|rcsb pdb:3AGG|rcsb pdb:3AGH|rcsb pdb:3AGI|rcsb pdb:3AJN|rcsb pdb:3ATN|rcsb pdb:3ATO|rcsb pdb:3AW6|rcsb pdb:3AW7|rcsb pdb:3AZ4|rcsb pdb:3AZ5|rcsb pdb:3AZ6|rcsb pdb:3AZ7|rcsb pdb:3B6L|rcsb pdb:3B72|rcsb pdb:3D9A|rcsb pdb:3E3D|rcsb pdb:3EMS|rcsb pdb:3EXD|rcsb pdb:3F6Z|rcsb pdb:3G3A|rcsb pdb:3G3B|rcsb pdb:3HFM|rcsb pdb:3IJU|rcsb pdb:2ZQ4|rcsb pdb:3IJV|rcsb pdb:3J4G|rcsb pdb:3J6K|rcsb pdb:3KAM|rcsb pdb:3LYT|rcsb pdb:3LYZ|rcsb pdb:3LZT|rcsb pdb:3M18|rcsb pdb:3M3U|rcsb pdb:3MBE|rcsb pdb:3N9A|rcsb pdb:3N9C|rcsb pdb:3N9E|rcsb pdb:3OJP|rcsb pdb:3OK0|rcsb pdb:3OTP|rcsb pdb:3P4Z|rcsb pdb:3P64|rcsb pdb:3P65|rcsb pdb:3P66|rcsb pdb:3P68|rcsb pdb:3QE8|rcsb pdb:3QNG|rcsb pdb:3QY4|rcsb pdb:3LYO|rcsb pdb:3RNX|rcsb pdb:3RT5|rcsb pdb:3LYM|rcsb pdb:3WU7|rcsb pdb:3WU8|rcsb pdb:3WU9|rcsb pdb:4B49|rcsb pdb:3WUA|rcsb pdb:3WUL|rcsb pdb:3WUM|rcsb pdb:3WUN|rcsb pdb:4B4E|rcsb pdb:3WVX|rcsb pdb:3WVY|rcsb pdb:3WW5|rcsb pdb:3WW6|rcsb pdb:3WXT|rcsb pdb:3WXU|rcsb pdb:3ZEK|rcsb pdb:3ZVQ|rcsb pdb:4A7D|rcsb pdb:4A8A|rcsb pdb:4A8B|rcsb pdb:4AGA|rcsb pdb:4AXT|rcsb pdb:4B0D|rcsb pdb:4B1A|rcsb pdb:3RW8|rcsb pdb:3RZ4|rcsb pdb:3SP3|rcsb pdb:3T6U|rcsb pdb:3TMU|rcsb pdb:3TMV|rcsb pdb:3TMW|rcsb pdb:3TMX|rcsb pdb:3TXB|rcsb pdb:3TXD|rcsb pdb:3TXE|rcsb pdb:3TXF|rcsb pdb:3TXG|rcsb pdb:3TXH|rcsb pdb:3TXI|rcsb pdb:3TXJ|rcsb pdb:3TXK|rcsb pdb:3ULR|rcsb pdb:3W6A|rcsb pdb:3WL2|rcsb pdb:3WMK|rcsb pdb:3RU5|rcsb pdb:3WPJ|rcsb pdb:3WPK|rcsb pdb:3WPL|rcsb pdb:4DDC|rcsb pdb:4DT3|rcsb pdb:4E3U|rcsb pdb:4BAD|rcsb pdb:4BAF|rcsb pdb:4BAP|rcsb pdb:4BS7|rcsb pdb:4C3W|rcsb pdb:4CJ2|rcsb pdb:4D9Z|rcsb pdb:4DC4|rcsb pdb:4DD0|rcsb pdb:4DD1|rcsb pdb:4DD2|rcsb pdb:4DD3|rcsb pdb:4DD7|rcsb pdb:4DD9|rcsb pdb:4DDA|rcsb pdb:4DDB|rcsb pdb:4EOF|rcsb pdb:4B4I|rcsb pdb:4B4J|rcsb pdb:4FJR|rcsb pdb:4G49|rcsb pdb:4G4B|rcsb pdb:4G4C|rcsb pdb:4G4H|rcsb pdb:4GCB|rcsb pdb:4GCC|rcsb pdb:4GCD|rcsb pdb:4GCE|rcsb pdb:4GCF|rcsb pdb:4GLA|rcsb pdb:4GLV|rcsb pdb:4GN3|rcsb pdb:4GN4|rcsb pdb:4GN5|rcsb pdb:4H1P|rcsb pdb:4H8X|rcsb pdb:4H8Y|rcsb pdb:4H8Z|rcsb pdb:4H90|rcsb pdb:4H91|rcsb pdb:4ETE|rcsb pdb:4H92|rcsb pdb:4H93|rcsb pdb:4H94|rcsb pdb:4H9A|rcsb pdb:4ET9|rcsb pdb:4ETA|rcsb pdb:4ETB|rcsb pdb:4ETC|rcsb pdb:4ETD|rcsb pdb:4ET8|rcsb pdb:4H9B|rcsb pdb:4H9C|rcsb pdb:4H9E|rcsb pdb:4H9F|rcsb pdb:4H9H|rcsb pdb:4H9I|rcsb pdb:4HP0|rcsb pdb:4HPI|rcsb pdb:4HSF|rcsb pdb:4HTK|rcsb pdb:4HTN|rcsb pdb:4HTQ|rcsb pdb:4HV1|rcsb pdb:4HV2|rcsb pdb:4I8S|rcsb pdb:4IAS|rcsb pdb:4IAT|rcsb pdb:4II8|rcsb pdb:4J1A|rcsb pdb:4J1B|rcsb pdb:4J7V|rcsb pdb:4KXI|rcsb pdb:4LFP|rcsb pdb:4PPO|rcsb pdb:4LFX|rcsb pdb:4LGK|rcsb pdb:4LT0|rcsb pdb:4LT1|rcsb pdb:4LT2|rcsb pdb:4LT3|rcsb pdb:4LYB|rcsb pdb:4LYC|rcsb pdb:4LYM|rcsb pdb:4LYO|rcsb pdb:4LYT|rcsb pdb:4LYZ|rcsb pdb:4LZT|rcsb pdb:4M4O|rcsb pdb:4M6D|rcsb pdb:4MR1|rcsb pdb:4N0J|rcsb pdb:4N1C|rcsb pdb:4N1E|rcsb pdb:4N5R|rcsb pdb:4N8Z|rcsb pdb:4N9R|rcsb pdb:4NEB|rcsb pdb:4NFV|rcsb pdb:4NG1|rcsb pdb:4NG8|rcsb pdb:4NGI|rcsb pdb:4NGJ|rcsb pdb:4NGL|rcsb pdb:4NGO|rcsb pdb:4NGV|rcsb pdb:4NGW|rcsb pdb:4NGY|rcsb pdb:4NGZ|rcsb pdb:4NHI|rcsb pdb:4NHP|rcsb pdb:4NHQ|rcsb pdb:4NHS|rcsb pdb:4NHT|rcsb pdb:4NGK|rcsb pdb:4NIJ|rcsb pdb:4NSG|rcsb pdb:4NSH|rcsb pdb:4NSI|rcsb pdb:4NSJ|rcsb pdb:4NWE|rcsb pdb:4NWH|rcsb pdb:4NY5|rcsb pdb:4O34|rcsb pdb:4OOO|rcsb pdb:4OOT|rcsb pdb:4OWA|rcsb pdb:4OWB|rcsb pdb:4OWC|rcsb pdb:4OWE|rcsb pdb:4OWH|rcsb pdb:4P2E|rcsb pdb:4PGJ|rcsb pdb:4PHI|rcsb pdb:4WG7|rcsb pdb:4WL6|rcsb pdb:4WL7|rcsb pdb:4WLD|rcsb pdb:4WLT|rcsb pdb:4WLX|rcsb pdb:4WLY|rcsb pdb:4WM1|rcsb pdb:4WM2|rcsb pdb:4WM3|rcsb pdb:4WM4|rcsb pdb:4WM5|rcsb pdb:4WM6|rcsb pdb:4PRU|rcsb pdb:4QEQ|rcsb pdb:4QGZ|rcsb pdb:4QY9|rcsb pdb:4R0F|rcsb pdb:4R6C|rcsb pdb:4RDS|rcsb pdb:4RLM|rcsb pdb:4RLN|rcsb pdb:4RW1|rcsb pdb:4RW2|rcsb pdb:4TSA|rcsb pdb:4TSB|rcsb pdb:4TSC|rcsb pdb:4TTD|rcsb pdb:4PRQ|rcsb pdb:4TUN|rcsb pdb:4TWS|rcsb pdb:4U3X|rcsb pdb:4UWN|rcsb pdb:4UWU|rcsb pdb:4UWV|rcsb pdb:4W94|rcsb pdb:4W96|rcsb pdb:4WG1|rcsb pdb:4WMG|rcsb pdb:4WO6|rcsb pdb:4WO9|rcsb pdb:4WOA|rcsb pdb:4X3B|rcsb pdb:4XAD|rcsb pdb:4XEN|rcsb pdb:4XJB|rcsb pdb:4XJD|rcsb pdb:4XJF|rcsb pdb:4XJG|rcsb pdb:4XJH|rcsb pdb:4XJI|rcsb pdb:4XN6|rcsb pdb:4XYY|rcsb pdb:4YEM|rcsb pdb:4YEN|rcsb pdb:4YEO|rcsb pdb:4YM8|rcsb pdb:4YOP|rcsb pdb:4Z3M|rcsb pdb:4Z41|rcsb pdb:4Z46|rcsb pdb:4Z98|rcsb pdb:4ZEE|rcsb pdb:4ZFP|rcsb pdb:4ZIX|rcsb pdb:5C6L|rcsb pdb:5D5C|rcsb pdb:5D5F|rcsb pdb:5A3E|rcsb pdb:5DL9|rcsb pdb:5DLA|rcsb pdb:5A3Z|rcsb pdb:5AMY|rcsb pdb:5APC|rcsb pdb:5APD|rcsb pdb:5APE|rcsb pdb:5DM9|rcsb pdb:5E4P|rcsb pdb:5E9R|rcsb pdb:5EBH|rcsb pdb:5F14|rcsb pdb:5F16|rcsb pdb:5F81|rcsb pdb:5F9U|rcsb pdb:5F9X|rcsb pdb:5APF|rcsb pdb:5B05|rcsb pdb:5B06|rcsb pdb:5B07|rcsb pdb:5B1F|rcsb pdb:5B1G|rcsb pdb:5B59|rcsb pdb:5FCP|rcsb pdb:5FDJ|rcsb pdb:5FEK|rcsb pdb:5FEL|rcsb pdb:5FHW|rcsb pdb:5FST|rcsb pdb:5GWB|rcsb pdb:5HLL|rcsb pdb:5HMJ|rcsb pdb:5HMV|rcsb pdb:5HNC|rcsb pdb:5HNL|rcsb pdb:5HQ1|rcsb pdb:5I4W|rcsb pdb:5I4X|rcsb pdb:5I4Y|rcsb pdb:5I53|rcsb pdb:5I54|rcsb pdb:5I5Q|rcsb pdb:5IDD|rcsb pdb:5IEL|rcsb pdb:5IHG|rcsb pdb:5II3|rcsb pdb:5ILC|rcsb pdb:5ILF|rcsb pdb:5J7C|rcsb pdb:5B5J|rcsb pdb:5C6I|rcsb pdb:5C6J|rcsb pdb:5JEN|rcsb pdb:5K2K|rcsb pdb:5K2N|rcsb pdb:6SIK|rcsb pdb:5NJP|rcsb pdb:5NJQ|rcsb pdb:5NJR|rcsb pdb:5NJS|rcsb pdb:5O4W|rcsb pdb:5O4X|rcsb pdb:5O6Q|rcsb pdb:5OB6|rcsb pdb:5OB7|rcsb pdb:5OB8|rcsb pdb:5OB9|rcsb pdb:5OCV|rcsb pdb:5OER|rcsb pdb:5OLE|rcsb pdb:5NJM|rcsb pdb:5OOV|rcsb pdb:5OOY|rcsb pdb:5OP1|rcsb pdb:5T3F|rcsb pdb:5TK0|rcsb pdb:5UVJ|rcsb pdb:5V4G|rcsb pdb:5V4H|rcsb pdb:5V4I|rcsb pdb:5WR9|rcsb pdb:5WRA|rcsb pdb:5WRB|rcsb pdb:5YIN|rcsb pdb:5YKY|rcsb pdb:6A10|rcsb pdb:6A4N|rcsb pdb:6A4O|rcsb pdb:6A4P|rcsb pdb:6A4Q|rcsb pdb:6ABN|rcsb pdb:6ABZ|rcsb pdb:6AC2|rcsb pdb:6AD5|rcsb pdb:6ADF|rcsb pdb:6AEA|rcsb pdb:6AGN|rcsb pdb:6AGR|rcsb pdb:6AHH|rcsb pdb:6AHL|rcsb pdb:6APM|rcsb pdb:6B7U|rcsb pdb:6B7V|rcsb pdb:6B7W|rcsb pdb:6BO1|rcsb pdb:6BO2|rcsb pdb:6BRE|rcsb pdb:6CIW|rcsb pdb:6D6E|rcsb pdb:6D6F|rcsb pdb:6D6G|rcsb pdb:6D6H|rcsb pdb:6F1L|rcsb pdb:6F1M|rcsb pdb:6F1O|rcsb pdb:6F1P|rcsb pdb:6F1R|rcsb pdb:6F2I|rcsb pdb:6F2J|rcsb pdb:6F2K|rcsb pdb:6F9X|rcsb pdb:6F9Y|rcsb pdb:6F9Z|rcsb pdb:6FA0|rcsb pdb:5K2P|rcsb pdb:5K2Q|rcsb pdb:5K2R|rcsb pdb:5K2S|rcsb pdb:5K7O|rcsb pdb:5KJ9|rcsb pdb:5KKI|rcsb pdb:5KKJ|rcsb pdb:5KXK|rcsb pdb:5KXL|rcsb pdb:5KXM|rcsb pdb:5KXN|rcsb pdb:5KXO|rcsb pdb:5KXP|rcsb pdb:5KXR|rcsb pdb:5KXS|rcsb pdb:5KXT|rcsb pdb:5KXW|rcsb pdb:5KXX|rcsb pdb:5KXY|rcsb pdb:5KXZ|rcsb pdb:5KY1|rcsb pdb:5L3H|rcsb pdb:5L3I|rcsb pdb:5L9J|rcsb pdb:5LA5|rcsb pdb:6FRO|rcsb pdb:5LA8|rcsb pdb:5LAF|rcsb pdb:5LAG|rcsb pdb:5LAN|rcsb pdb:5LIN|rcsb pdb:5LIO|rcsb pdb:5LVG|rcsb pdb:5LVH|rcsb pdb:5LVI|rcsb pdb:5LVJ|rcsb pdb:5LXW|rcsb pdb:5LYM|rcsb pdb:5LYT|rcsb pdb:5LYZ|rcsb pdb:5M1Y|rcsb pdb:5MJJ|rcsb pdb:5MYY|rcsb pdb:5NBJ|rcsb pdb:5NE0|rcsb pdb:5NJ1|rcsb pdb:6FRQ|rcsb pdb:6FSJ|rcsb pdb:6FTR|rcsb pdb:6G5C|rcsb pdb:6G5V|rcsb pdb:6G5Y|rcsb pdb:6G8A|rcsb pdb:6GF0|rcsb pdb:6GNL|rcsb pdb:6GOB|rcsb pdb:6GOH|rcsb pdb:6GOI|rcsb pdb:6GOJ|rcsb pdb:6H0K|rcsb pdb:6H0L|rcsb pdb:6H3B|rcsb pdb:6H79|rcsb pdb:6HT2|rcsb pdb:6HU5|rcsb pdb:6HY4|rcsb pdb:6HY6|rcsb pdb:6HY8|rcsb pdb:6HYB|rcsb pdb:6IG6|rcsb pdb:6IRJ|rcsb pdb:6JB2|rcsb pdb:6JB5|rcsb pdb:6JB8|rcsb pdb:6JXP|rcsb pdb:6JXQ|rcsb pdb:6JZI|rcsb pdb:6K5Q|rcsb pdb:6K8G|rcsb pdb:6KCB|rcsb pdb:6KCD|rcsb pdb:6KD1|rcsb pdb:6LAV|rcsb pdb:6LL3|rcsb pdb:6LT5|rcsb pdb:6LYT|rcsb pdb:6LYZ|rcsb pdb:6MQV|rcsb pdb:6MUZ|rcsb pdb:6MX9|rcsb pdb:6O2H|rcsb pdb:6P4A|rcsb pdb:6P4B|rcsb pdb:6P4D|rcsb pdb:6PBB|rcsb pdb:6PL9|rcsb pdb:6PLA|rcsb pdb:6PLB|rcsb pdb:6Q88|rcsb pdb:6Q8R|rcsb pdb:6Q8T|rcsb pdb:6QEA|rcsb pdb:6QNB|rcsb pdb:6QQ3|rcsb pdb:6QQC|rcsb pdb:6QQD|rcsb pdb:6QQE|rcsb pdb:6QQF|rcsb pdb:6QWW|rcsb pdb:6QWX|rcsb pdb:6QWY|rcsb pdb:6QWZ|rcsb pdb:6QX0|rcsb pdb:6QXW|rcsb pdb:6QXX|rcsb pdb:6QXY|rcsb pdb:6QY0|rcsb pdb:6QY1|rcsb pdb:6QY2|rcsb pdb:6QY4|rcsb pdb:6QY5|rcsb pdb:6RNB|rcsb pdb:6RNC|rcsb pdb:6RO3|rcsb pdb:6RO5|rcsb pdb:6RT1|rcsb pdb:6RT3|rcsb pdb:6RT9|rcsb pdb:6RTA|rcsb pdb:6RXI|rcsb pdb:6S2N|rcsb pdb:6S7N|rcsb pdb:6SET|rcsb pdb:6SEU|rcsb pdb:6SEW|rcsb pdb:6SEX|rcsb pdb:6SEZ|rcsb pdb:6SIJ|rcsb pdb:6SIL|rcsb pdb:6SIM|rcsb pdb:6SR0|rcsb pdb:6SR1|rcsb pdb:6SR2|rcsb pdb:6SR3|rcsb pdb:6SR4|rcsb pdb:6SR5|rcsb pdb:6SYC|rcsb pdb:6SYD|rcsb pdb:6SYE|rcsb pdb:6TVL|rcsb pdb:6TVY|rcsb pdb:6W7P|rcsb pdb:6W8E|rcsb pdb:6WRL|rcsb pdb:6WRM|rcsb pdb:6WX5|rcsb pdb:6YBF|rcsb pdb:6YBI|rcsb pdb:6YJX|rcsb pdb:6YOB|rcsb pdb:6YOC|rcsb pdb:6YOD|rcsb pdb:6YOE|rcsb pdb:6ZS8|rcsb pdb:7A70|rcsb pdb:7BE2|rcsb pdb:7BEB|rcsb pdb:7BEC|rcsb pdb:7BR5|rcsb pdb:7BVM|rcsb pdb:7BVO|rcsb pdb:7BYO|rcsb pdb:7BYP|rcsb pdb:7C09|rcsb pdb:7AVE|rcsb pdb:7AVF|rcsb pdb:7AVG|rcsb pdb:7BDZ|rcsb pdb:7BE0|rcsb pdb:7BE1|rcsb pdb:7CDK|rcsb pdb:7CDM|rcsb pdb:7CDN|rcsb pdb:7CDO|rcsb pdb:7CDP|rcsb pdb:7CDQ|rcsb pdb:7CDR|rcsb pdb:7CDS|rcsb pdb:7CDT|rcsb pdb:7CDU|rcsb pdb:7CJZ|rcsb pdb:7DEQ|rcsb pdb:7DER|rcsb pdb:7DTB|rcsb pdb:7DTF|rcsb pdb:7E02|rcsb pdb:7JMU|rcsb pdb:7KH5|rcsb pdb:7L84|rcsb pdb:7LYZ|rcsb pdb:7NJF|rcsb pdb:7NKF|rcsb pdb:8LYZ|rcsb pdb:9LYZ|reactome:R-GGA-6798695|reactome:R-GGA-6803157|rcsb pdb:7CVJ|rcsb pdb:7CVL|rcsb pdb:7D01|rcsb pdb:7D02|rcsb pdb:7D04|rcsb pdb:7D05|rcsb pdb:7D0W|refseq:NP_990612.1|dip:DIP-46258N|mint:MINT-8413703(identity) - - - figure legend:f3|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/06 2014/10/16 rogid:h5MqSdRIthgxU5zzOYEGbZmMvo89031 rogid:h5MqSdRIthgxU5zzOYEGbZmMvo89031 intact-crc:E77925DFFE5D66EA|rigid:ERUQG9grlkQm2hq2L8sKEtn392o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00711 uniprotkb:P00711 intact:EBI-7080486|intact:MINT-1487560|uniprotkb:Q95NE4|uniprotkb:Q3T111 intact:EBI-7080486|intact:MINT-1487560|uniprotkb:Q95NE4|uniprotkb:Q3T111 psi-mi:lalba_bovin(display_long)|uniprotkb:LALBA(gene name)|psi-mi:LALBA(display_short)|uniprotkb:ALACTA(gene name synonym)|uniprotkb:Lactose synthase B protein(gene name synonym) psi-mi:lalba_bovin(display_long)|uniprotkb:LALBA(gene name)|psi-mi:LALBA(display_short)|uniprotkb:ALACTA(gene name synonym)|uniprotkb:Lactose synthase B protein(gene name synonym) psi-mi:"MI:0016"(circular dichroism) Babenko et al. (2013) pubmed:23416304|mint:MINT-8413634|mint:d-12-02034r1 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8438116|mint:MINT-8413713 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P00711|go:"GO:0004461"(lactose synthase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005989"(lactose biosynthetic process)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0042802"(identical protein binding)|go:"GO:1903494"(response to dehydroepiandrosterone)|go:"GO:1903496"(response to 11-deoxycorticosterone)|rcsb pdb:1F6R|rcsb pdb:1F6S|rcsb pdb:1HFZ|rcsb pdb:2G4N|rcsb pdb:6IP9|interpro:IPR019799|interpro:IPR023346|refseq:NP_776803.1|interpro:IPR000545(Lactalbumin)|interpro:IPR001916(Glycoside hydrolase, family 22)|mint:MINT-8413715(identity) mint:P00711|go:"GO:0004461"(lactose synthase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005989"(lactose biosynthetic process)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0042802"(identical protein binding)|go:"GO:1903494"(response to dehydroepiandrosterone)|go:"GO:1903496"(response to 11-deoxycorticosterone)|rcsb pdb:1F6R|rcsb pdb:1F6S|rcsb pdb:1HFZ|rcsb pdb:2G4N|rcsb pdb:6IP9|interpro:IPR019799|interpro:IPR023346|refseq:NP_776803.1|interpro:IPR000545(Lactalbumin)|interpro:IPR001916(Glycoside hydrolase, family 22)|mint:MINT-8413717(identity) - comment:mint|comment:homomint|function:Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins comment:mint|comment:homomint|function:Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins figure legend:f3|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/06 2014/10/16 rogid:jEnBQQgOzSEaNmxGJLAV+KkbnGs9913 rogid:jEnBQQgOzSEaNmxGJLAV+KkbnGs9913 intact-crc:3A09679F6F554C77|rigid:MdCDDLqiv0e0UnUzr+i9rARQ7Zw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)