#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6PCN7 uniprotkb:P07356 intact:EBI-6869770|ensembl:ENSMUSP00000002502|uniprotkb:O35596|uniprotkb:O35597|uniprotkb:Q80VT6 intact:EBI-738510|ensembl:ENSMUSP00000034756 psi-mi:hltf_mouse(display_long)|uniprotkb:Hltf(gene name)|psi-mi:Hltf(display_short)|uniprotkb:Smarca3(gene name synonym)|uniprotkb:Snf2l3(gene name synonym)|uniprotkb:Zbu1(gene name synonym)|uniprotkb:P113(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:TNF-response element-binding protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869766|imex:IM-20914-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000002502(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|reactome:R-MMU-8866654|ensembl:ENSMUSG00000002428(gene)|refseq:XP_006535491.1|refseq:NP_033236.2 refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205 - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2013/06/25 2014/10/16 rogid:iZhxC9wBoKZ9ZYCaEnNUbg1x2i410090 rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090 intact-crc:DFEF310E060B7FDF|rigid:3wtQ+IlGDmudm6NxE68qOprS2gc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6PCN7 uniprotkb:P08207 intact:EBI-6869770|ensembl:ENSMUSP00000002502|uniprotkb:O35596|uniprotkb:O35597|uniprotkb:Q80VT6 intact:EBI-643986|ensembl:ENSMUSP00000036949|ensembl:ENSMUSP00000130712 psi-mi:hltf_mouse(display_long)|uniprotkb:Hltf(gene name)|psi-mi:Hltf(display_short)|uniprotkb:Smarca3(gene name synonym)|uniprotkb:Snf2l3(gene name synonym)|uniprotkb:Zbu1(gene name synonym)|uniprotkb:P113(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:TNF-response element-binding protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:s10aa_mouse(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:Cal1l(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869766|imex:IM-20914-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000002502(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|reactome:R-MMU-8866654|ensembl:ENSMUSG00000002428(gene)|refseq:XP_006535491.1|refseq:NP_033236.2 refseq:NP_033138.1|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|mint:P08207|reactome:R-MMU-75205|go:"GO:0072659"(protein localization to plasma membrane)|ensembl:ENSMUSG00000041959(gene)|ensembl:ENSMUST00000045756(transcript)|ensembl:ENSMUST00000170612(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix) - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2013/06/25 2014/10/16 rogid:iZhxC9wBoKZ9ZYCaEnNUbg1x2i410090 rogid:ZMDpz9SmMc3cQ195GiMFbhaCuR410090 intact-crc:DFEF310E060B7FDF|rigid:3wtQ+IlGDmudm6NxE68qOprS2gc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6874658 intact:EBI-6868540 - - psi-mi:hltf_chlae_protein(display_short)|psi-mi:EBI-6874658(display_long) psi-mi:s10aa_chlae_protein(display_short)|psi-mi:EBI-6868540(display_long) psi-mi:"MI:0416"(fluorescence microscopy) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6874660|imex:IM-20914-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - - go:"GO:0005634"(nucleus) comment:Similar to Q14527 comment:Similar to P62504 figure legend:Fig. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 - - intact-crc:E52684BC6D414E9B false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q6PCN7 uniprotkb:P08207 intact:EBI-6869770|ensembl:ENSMUSP00000002502|uniprotkb:O35596|uniprotkb:O35597|uniprotkb:Q80VT6 intact:EBI-643986|ensembl:ENSMUSP00000036949|ensembl:ENSMUSP00000130712 psi-mi:hltf_mouse(display_long)|uniprotkb:Hltf(gene name)|psi-mi:Hltf(display_short)|uniprotkb:Smarca3(gene name synonym)|uniprotkb:Snf2l3(gene name synonym)|uniprotkb:Zbu1(gene name synonym)|uniprotkb:P113(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:TNF-response element-binding protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:s10aa_mouse(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:Cal1l(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6874929|imex:IM-20914-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000002502(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|reactome:R-MMU-8866654|ensembl:ENSMUSG00000002428(gene)|refseq:XP_006535491.1|refseq:NP_033236.2 refseq:NP_033138.1|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|mint:P08207|reactome:R-MMU-75205|go:"GO:0072659"(protein localization to plasma membrane)|ensembl:ENSMUSG00000041959(gene)|ensembl:ENSMUST00000045756(transcript)|ensembl:ENSMUST00000170612(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix) - - - figure legend:Fig. 6F|agonist:"Fluoxetine (a selective serotonin re-uptake inhibitor) for 2 weeks"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-hippocampus)|taxid:10090(Mus musculus) - 2013/06/25 2014/10/16 rogid:iZhxC9wBoKZ9ZYCaEnNUbg1x2i410090 rogid:ZMDpz9SmMc3cQ195GiMFbhaCuR410090 intact-crc:8D9FFC7D509688F3|rigid:3wtQ+IlGDmudm6NxE68qOprS2gc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6PCN7 uniprotkb:P07356 intact:EBI-6869770|ensembl:ENSMUSP00000002502|uniprotkb:O35596|uniprotkb:O35597|uniprotkb:Q80VT6 intact:EBI-738510|ensembl:ENSMUSP00000034756 psi-mi:hltf_mouse(display_long)|uniprotkb:Hltf(gene name)|psi-mi:Hltf(display_short)|uniprotkb:Smarca3(gene name synonym)|uniprotkb:Snf2l3(gene name synonym)|uniprotkb:Zbu1(gene name synonym)|uniprotkb:P113(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:TNF-response element-binding protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6874929|imex:IM-20914-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000002502(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|reactome:R-MMU-8866654|ensembl:ENSMUSG00000002428(gene)|refseq:XP_006535491.1|refseq:NP_033236.2 refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205 - - - figure legend:Fig. 6F|agonist:"Fluoxetine (a selective serotonin re-uptake inhibitor) for 2 weeks"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-hippocampus)|taxid:10090(Mus musculus) - 2013/06/25 2014/10/16 rogid:iZhxC9wBoKZ9ZYCaEnNUbg1x2i410090 rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090 intact-crc:8D9FFC7D509688F3|rigid:3wtQ+IlGDmudm6NxE68qOprS2gc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P08207 uniprotkb:P07356 intact:EBI-643986|ensembl:ENSMUSP00000036949|ensembl:ENSMUSP00000130712 intact:EBI-738510|ensembl:ENSMUSP00000034756 psi-mi:s10aa_mouse(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:Cal1l(gene name synonym) psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6868464|imex:IM-20914-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033138.1|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|mint:P08207|reactome:R-MMU-75205|go:"GO:0072659"(protein localization to plasma membrane)|ensembl:ENSMUSG00000041959(gene)|ensembl:ENSMUST00000045756(transcript)|ensembl:ENSMUST00000170612(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix) refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205 - - - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-hippocampus)|taxid:10090(Mus musculus) - 2013/06/25 2014/10/16 rogid:ZMDpz9SmMc3cQ195GiMFbhaCuR410090 rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090 intact-crc:0923963B22ED1575|rigid:uR3Z78KtbXjP+GNpSv7AWhdK74w false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 uniprotkb:Q09666 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 intact:EBI-2555881|ensembl:ENSP00000367263|uniprotkb:A1A586 psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869670|imex:IM-20914-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 refseq:NP_001611.1|ensembl:ENSG00000124942(gene)|ensembl:ENST00000378024(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|refseq:NP_001333374.1|refseq:NP_001333375.1|refseq:NP_076965.2 - - - figure legend:Fig. 2B|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 rogid:u1oecAyIihgxzfTz0jholE8wksA9606 intact-crc:F3D22F7BCA6C8EFC|rigid:elMobvj7L3ToOqyoiMCw5vZBO6c false mutation decreasing interaction strength:83-83|flag tag:?-?|mutation decreasing interaction strength:83-83 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 uniprotkb:P07355 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869670|imex:IM-20914-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - - figure legend:Fig. 2B|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 intact-crc:F3D22F7BCA6C8EFC|rigid:elMobvj7L3ToOqyoiMCw5vZBO6c false mutation decreasing interaction strength:83-83|flag tag:?-?|mutation decreasing interaction strength:83-83 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 uniprotkb:Q14527 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869670|imex:IM-20914-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 - - - figure legend:Fig. 2B|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 intact-crc:F3D22F7BCA6C8EFC|rigid:elMobvj7L3ToOqyoiMCw5vZBO6c false mutation decreasing interaction strength:83-83|flag tag:?-?|mutation decreasing interaction strength:83-83 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 uniprotkb:P60903 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801 psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869670|imex:IM-20914-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205 - - - figure legend:Fig. 2B|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606 intact-crc:F3D22F7BCA6C8EFC|rigid:elMobvj7L3ToOqyoiMCw5vZBO6c false mutation decreasing interaction strength:83-83|flag tag:?-?|mutation decreasing interaction strength:83-83 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 uniprotkb:Q7KZ85 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 intact:EBI-2515547|ensembl:ENSP00000319104|ensembl:ENSP00000338143|uniprotkb:Q96AH3|uniprotkb:Q7KYW9|uniprotkb:Q6GMQ4|uniprotkb:Q8N526|uniprotkb:Q15737|uniprotkb:Q9BTI2|uniprotkb:Q92775|uniprotkb:Q9BTH9|uniprotkb:Q7LDK4|uniprotkb:A7E2B4 psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:spt6h_human(display_long)|uniprotkb:SUPT6H(gene name)|psi-mi:SUPT6H(display_short)|uniprotkb:KIAA0162(gene name synonym)|uniprotkb:SPT6H(gene name synonym)|uniprotkb:Tat-cotransactivator 2 protein(gene name synonym)|uniprotkb:Histone chaperone suppressor of Ty6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869670|imex:IM-20914-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035327"|go:"GO:0042393"(histone binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045191"(regulation of isotype switching)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0051028"(mRNA transport)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070827"(obsolete chromatin maintenance)|interpro:IPR000980(SH2 motif)|interpro:IPR003029(S1, RNA binding)|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR017072(Transcription elongation factor Spt6)|interpro:IPR022967|interpro:IPR023319|interpro:IPR028083|interpro:IPR028088|interpro:IPR028231|interpro:IPR032706|interpro:IPR035018|interpro:IPR035019|interpro:IPR035420|interpro:IPR036860|interpro:IPR037027|interpro:IPR041692|interpro:IPR042066|mint:Q7KZ85|rcsb pdb:6GME|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|interpro:IPR023323|ensembl:ENSG00000109111(gene)|ensembl:ENST00000314616(transcript)|ensembl:ENST00000347486(transcript)|go:"GO:0001825"(blastocyst formation)|refseq:XP_016880467.1|refseq:XP_016880468.1|refseq:XP_016880469.1|refseq:NP_003161.2|refseq:NP_001307684.1|dip:DIP-42615N - - - figure legend:Fig. 2B|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 rogid:G1HKe2xEnti5tcZvbH4uqLOwKNg9606 intact-crc:F3D22F7BCA6C8EFC|rigid:elMobvj7L3ToOqyoiMCw5vZBO6c false mutation decreasing interaction strength:83-83|flag tag:?-?|mutation decreasing interaction strength:83-83 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 uniprotkb:Q09666 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 intact:EBI-2555881|ensembl:ENSP00000367263|uniprotkb:A1A586 psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869645|imex:IM-20914-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 refseq:NP_001611.1|ensembl:ENSG00000124942(gene)|ensembl:ENST00000378024(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|refseq:NP_001333374.1|refseq:NP_001333375.1|refseq:NP_076965.2 - - - figure legend:Fig. 2A|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 rogid:u1oecAyIihgxzfTz0jholE8wksA9606 intact-crc:8E2CA3742D6D918B|rigid:elMobvj7L3ToOqyoiMCw5vZBO6c false mutation decreasing interaction strength:83-83|mutation decreasing interaction strength:83-83|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05943 uniprotkb:Q7KZ85 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 intact:EBI-2515547|ensembl:ENSP00000319104|ensembl:ENSP00000338143|uniprotkb:Q96AH3|uniprotkb:Q7KYW9|uniprotkb:Q6GMQ4|uniprotkb:Q8N526|uniprotkb:Q15737|uniprotkb:Q9BTI2|uniprotkb:Q92775|uniprotkb:Q9BTH9|uniprotkb:Q7LDK4|uniprotkb:A7E2B4 psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:spt6h_human(display_long)|uniprotkb:SUPT6H(gene name)|psi-mi:SUPT6H(display_short)|uniprotkb:KIAA0162(gene name synonym)|uniprotkb:SPT6H(gene name synonym)|uniprotkb:Tat-cotransactivator 2 protein(gene name synonym)|uniprotkb:Histone chaperone suppressor of Ty6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869645|imex:IM-20914-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035327"|go:"GO:0042393"(histone binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045191"(regulation of isotype switching)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0051028"(mRNA transport)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070827"(obsolete chromatin maintenance)|interpro:IPR000980(SH2 motif)|interpro:IPR003029(S1, RNA binding)|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR017072(Transcription elongation factor Spt6)|interpro:IPR022967|interpro:IPR023319|interpro:IPR028083|interpro:IPR028088|interpro:IPR028231|interpro:IPR032706|interpro:IPR035018|interpro:IPR035019|interpro:IPR035420|interpro:IPR036860|interpro:IPR037027|interpro:IPR041692|interpro:IPR042066|mint:Q7KZ85|rcsb pdb:6GME|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|interpro:IPR023323|ensembl:ENSG00000109111(gene)|ensembl:ENST00000314616(transcript)|ensembl:ENST00000347486(transcript)|go:"GO:0001825"(blastocyst formation)|refseq:XP_016880467.1|refseq:XP_016880468.1|refseq:XP_016880469.1|refseq:NP_003161.2|refseq:NP_001307684.1|dip:DIP-42615N - - - figure legend:Fig. 2A|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 rogid:G1HKe2xEnti5tcZvbH4uqLOwKNg9606 intact-crc:8E2CA3742D6D918B|rigid:elMobvj7L3ToOqyoiMCw5vZBO6c false mutation decreasing interaction strength:83-83|mutation decreasing interaction strength:83-83|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05943 uniprotkb:P07355 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869645|imex:IM-20914-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - - figure legend:Fig. 2A|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 intact-crc:8E2CA3742D6D918B|rigid:elMobvj7L3ToOqyoiMCw5vZBO6c false mutation decreasing interaction strength:83-83|mutation decreasing interaction strength:83-83|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05943 uniprotkb:Q14527 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869645|imex:IM-20914-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 - - - figure legend:Fig. 2A|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 intact-crc:8E2CA3742D6D918B|rigid:elMobvj7L3ToOqyoiMCw5vZBO6c false mutation decreasing interaction strength:83-83|mutation decreasing interaction strength:83-83|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05943 uniprotkb:P60903 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801 psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869645|imex:IM-20914-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205 - - - figure legend:Fig. 2A|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606 intact-crc:8E2CA3742D6D918B|rigid:elMobvj7L3ToOqyoiMCw5vZBO6c false mutation decreasing interaction strength:83-83|mutation decreasing interaction strength:83-83|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09666 uniprotkb:P08207 intact:EBI-2555881|ensembl:ENSP00000367263|uniprotkb:A1A586 intact:EBI-643986|ensembl:ENSMUSP00000036949|ensembl:ENSMUSP00000130712 psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short) psi-mi:s10aa_mouse(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:Cal1l(gene name synonym) psi-mi:"MI:0096"(pull down) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869830|imex:IM-20914-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001611.1|ensembl:ENSG00000124942(gene)|ensembl:ENST00000378024(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|refseq:NP_001333374.1|refseq:NP_001333375.1|refseq:NP_076965.2 refseq:NP_033138.1|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|mint:P08207|reactome:R-MMU-75205|go:"GO:0072659"(protein localization to plasma membrane)|ensembl:ENSMUSG00000041959(gene)|ensembl:ENSMUST00000045756(transcript)|ensembl:ENSMUST00000170612(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix) - - - figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/06/25 2014/10/16 rogid:u1oecAyIihgxzfTz0jholE8wksA9606 rogid:ZMDpz9SmMc3cQ195GiMFbhaCuR410090 intact-crc:CEC64FD042C34C28|rigid:qppN4i//7AQskYpMQbXdr5ssnD0 false sufficient binding region:5654-5671|biotin tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q09666 uniprotkb:P07356 intact:EBI-2555881|ensembl:ENSP00000367263|uniprotkb:A1A586 intact:EBI-738510|ensembl:ENSMUSP00000034756 psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short) psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0096"(pull down) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869830|imex:IM-20914-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001611.1|ensembl:ENSG00000124942(gene)|ensembl:ENST00000378024(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|refseq:NP_001333374.1|refseq:NP_001333375.1|refseq:NP_076965.2 refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205 - - - figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/06/25 2014/10/16 rogid:u1oecAyIihgxzfTz0jholE8wksA9606 rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090 intact-crc:CEC64FD042C34C28|rigid:qppN4i//7AQskYpMQbXdr5ssnD0 false sufficient binding region:5654-5671|biotin tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6871657 uniprotkb:P08207 - intact:EBI-643986|ensembl:ENSMUSP00000036949|ensembl:ENSMUSP00000130712 psi-mi:b-box_pai1_3-5prime(display_short)|psi-mi:EBI-6871657(display_long) psi-mi:s10aa_mouse(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:Cal1l(gene name synonym) psi-mi:"MI:0096"(pull down) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6873916|imex:IM-20914-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_033138.1|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|mint:P08207|reactome:R-MMU-75205|go:"GO:0072659"(protein localization to plasma membrane)|ensembl:ENSMUSG00000041959(gene)|ensembl:ENSMUST00000045756(transcript)|ensembl:ENSMUST00000170612(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix) - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/06/25 2014/10/16 - rogid:ZMDpz9SmMc3cQ195GiMFbhaCuR410090 intact-crc:951C9F33D0D2245C false biotin tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6871657 uniprotkb:Q14527 - intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 psi-mi:b-box_pai1_3-5prime(display_short)|psi-mi:EBI-6871657(display_long) psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:"MI:0096"(pull down) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6873916|imex:IM-20914-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/06/25 2014/10/16 - rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 intact-crc:951C9F33D0D2245C false biotin tag:?-? sufficient binding region:1-350 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6871657 uniprotkb:P07356 - intact:EBI-738510|ensembl:ENSMUSP00000034756 psi-mi:b-box_pai1_3-5prime(display_short)|psi-mi:EBI-6871657(display_long) psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0096"(pull down) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6873916|imex:IM-20914-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/06/25 2014/10/16 - rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090 intact-crc:951C9F33D0D2245C false biotin tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6871657 uniprotkb:Q14527 - intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 psi-mi:b-box_pai1_3-5prime(display_short)|psi-mi:EBI-6871657(display_long) psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:"MI:0096"(pull down) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6873936|imex:IM-20914-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/06/25 2014/10/16 - rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 intact-crc:A4BD6E488442D7B5 false biotin tag:?-? sufficient binding region:1-350 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14527 uniprotkb:P08207 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 intact:EBI-643986|ensembl:ENSMUSP00000036949|ensembl:ENSMUSP00000130712 psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:s10aa_mouse(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:Cal1l(gene name synonym) psi-mi:"MI:0096"(pull down) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869970|imex:IM-20914-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 refseq:NP_033138.1|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|mint:P08207|reactome:R-MMU-75205|go:"GO:0072659"(protein localization to plasma membrane)|ensembl:ENSMUSG00000041959(gene)|ensembl:ENSMUST00000045756(transcript)|ensembl:ENSMUST00000170612(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix) - - - figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/06/25 2014/10/16 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rogid:ZMDpz9SmMc3cQ195GiMFbhaCuR410090 intact-crc:C66A18139C719CC9|rigid:sSF6g3zXCQ2xA+FBW0AXI9lonwI false sufficient binding region:26-42|biotin tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14527 uniprotkb:P07356 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 intact:EBI-738510|ensembl:ENSMUSP00000034756 psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0096"(pull down) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869970|imex:IM-20914-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205 - - - figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/06/25 2014/10/16 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090 intact-crc:C66A18139C719CC9|rigid:sSF6g3zXCQ2xA+FBW0AXI9lonwI false sufficient binding region:26-42|biotin tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q09666 uniprotkb:P60903 intact:EBI-2555881|ensembl:ENSP00000367263|uniprotkb:A1A586 intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801 psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short) psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6870038|pdbe:4hrg|imex:IM-20914-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001611.1|ensembl:ENSG00000124942(gene)|ensembl:ENST00000378024(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|refseq:NP_001333374.1|refseq:NP_001333375.1|refseq:NP_076965.2 refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205 - - - figure legend:Supp. Table 1|3d-r-factors:Rwork = 0.19 Rfree = 0.22|3d-resolution:2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/06/25 2014/10/16 rogid:u1oecAyIihgxzfTz0jholE8wksA9606 rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606 intact-crc:1BBE7A015C9956E2|rigid:lRmPQTO3SISK/WXfo/ADyTyuldo false sufficient binding region:5655-5668 sufficient binding region:1-93 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08207 uniprotkb:P07356 intact:EBI-643986|ensembl:ENSMUSP00000036949|ensembl:ENSMUSP00000130712 intact:EBI-738510|ensembl:ENSMUSP00000034756 psi-mi:s10aa_mouse(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:Cal1l(gene name synonym) psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6868449|imex:IM-20914-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033138.1|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|mint:P08207|reactome:R-MMU-75205|go:"GO:0072659"(protein localization to plasma membrane)|ensembl:ENSMUSG00000041959(gene)|ensembl:ENSMUST00000045756(transcript)|ensembl:ENSMUST00000170612(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix) refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205 - - - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-n2a)|taxid:10090(Mouse neuroblastoma cells) - 2013/06/25 2014/10/16 rogid:ZMDpz9SmMc3cQ195GiMFbhaCuR410090 rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090 intact-crc:63A98F2AA9B209A2|rigid:uR3Z78KtbXjP+GNpSv7AWhdK74w false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 intact:EBI-6868540 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 - psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:s10aa_chlae_protein(display_short)|psi-mi:EBI-6868540(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6869625|imex:IM-20914-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 - - - comment:Similar to P62504 figure legend:Supp. Fig. 1A|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 - intact-crc:0BAD8A2125EC8462 false flag tag:?-?|mutation:83-83|mutation:83-83 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 intact:EBI-8785901 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 - psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:anxa2_chlae_protein(display_short)|psi-mi:EBI-8785901(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6868498|imex:IM-20914-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 - - - comment:similar to P07355 figure legend:Supp. Fig. 1A|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 - intact-crc:7ABBECFC700FFCA9 false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 intact:EBI-6868540 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 - psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:s10aa_chlae_protein(display_short)|psi-mi:EBI-6868540(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6868498|imex:IM-20914-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 - - - comment:Similar to P62504 figure legend:Supp. Fig. 1A|comment:Cys83Ser and Cys83Gln mutations in p11 significantly decreased the interaction with AnxA2, without altering the interaction with endogenous p11 to form a p11 dimer.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 - intact-crc:7ABBECFC700FFCA9 false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 intact:EBI-8785901 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 - psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:anxa2_chlae_protein(display_short)|psi-mi:EBI-8785901(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6870166|imex:IM-20914-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 - - - comment:similar to P07355 figure legend:Supp. Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 - intact-crc:159382AAEEF40720 false flag tag:?-?|mutation:60-60 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 intact:EBI-6868540 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 - psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:s10aa_chlae_protein(display_short)|psi-mi:EBI-6868540(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6870166|imex:IM-20914-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 - - - comment:Similar to P62504 figure legend:Supp. Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 - intact-crc:159382AAEEF40720 false flag tag:?-?|mutation:60-60 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14527 intact:EBI-6868540 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 - psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:s10aa_chlae_protein(display_short)|psi-mi:EBI-6868540(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6870077|imex:IM-20914-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 - - - comment:Similar to P62504 figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 - intact-crc:6E063D290B620F94 false mutation decreasing interaction strength:37-37|mutation decreasing interaction strength:35-35|v5 tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14527 intact:EBI-8785901 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 - psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:anxa2_chlae_protein(display_short)|psi-mi:EBI-8785901(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6870077|imex:IM-20914-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 - - - comment:similar to P07355 figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 - intact-crc:6E063D290B620F94 false mutation decreasing interaction strength:37-37|mutation decreasing interaction strength:35-35|v5 tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P07356 intact:EBI-6868540 intact:EBI-738510|ensembl:ENSMUSP00000034756 - psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:s10aa_chlae_protein(display_short)|psi-mi:EBI-6868540(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6870125|imex:IM-20914-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205 - - - comment:Similar to P62504 figure legend:Supp. Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090 - intact-crc:ED74763E347B9568 false mutation decreasing interaction strength:8-8|mutation decreasing interaction strength:11-11|myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P07356 intact:EBI-6874658 intact:EBI-738510|ensembl:ENSMUSP00000034756 - psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:hltf_chlae_protein(display_short)|psi-mi:EBI-6874658(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6870125|imex:IM-20914-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205 - - - comment:Similar to Q14527 figure legend:Supp. Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090 - intact-crc:ED74763E347B9568 false mutation decreasing interaction strength:8-8|mutation decreasing interaction strength:11-11|myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 intact:EBI-8785901 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 - psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:anxa2_chlae_protein(display_short)|psi-mi:EBI-8785901(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6870152|imex:IM-20914-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 - - - comment:similar to P07355 figure legend:Supp. Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 - intact-crc:1B52E3E6F4CD696C false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 intact:EBI-6874658 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 - psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:hltf_chlae_protein(display_short)|psi-mi:EBI-6874658(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6870152|imex:IM-20914-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 - - - comment:Similar to Q14527 figure legend:Supp. Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 - intact-crc:1B52E3E6F4CD696C false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05943 intact:EBI-6868540 intact:EBI-1800351|uniprotkb:Q5BJ98|ensembl:ENSRNOP00000037097 - psi-mi:s10aa_rat(display_long)|uniprotkb:S100a10(gene name)|psi-mi:S100a10(display_short)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:Nerve growth factor-induced protein 42C(gene name synonym) psi-mi:s10aa_chlae_protein(display_short)|psi-mi:EBI-6868540(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6870152|imex:IM-20914-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:628655|refseq:NP_112376.1|ensembl:ENSRNOG00000023226(gene)|ensembl:ENSRNOT00000035240(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|reactome:R-RNO-75205 - - - comment:Similar to P62504 figure legend:Supp. Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 rogid:/MGaZckvZx44usKBC50esHsGgy810116 - intact-crc:1B52E3E6F4CD696C false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6868540 uniprotkb:P07356 - intact:EBI-738510|ensembl:ENSMUSP00000034756 psi-mi:s10aa_chlae_protein(display_short)|psi-mi:EBI-6868540(display_long) psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6870142|imex:IM-20914-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205 - comment:Similar to P62504 - figure legend:Supp. Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2013/06/25 2014/10/16 - rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090 intact-crc:E0251A5BE1A15FEF false - mutation:13-13|myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14527 uniprotkb:P60903 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801 psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym) psi-mi:"MI:0096"(pull down) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6869696|imex:IM-20914-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205 - - - figure legend:Fig. 2D, Supp. Fig. 1B, 1C, 1D|comment:The s100a10-SMARCA3 interaction was significantly increased by the addition of AnxA2 to the pull-down assay mixture|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/06/25 2014/10/16 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606 intact-crc:B5EE12D5E05570C1|rigid:ZXSnt/YpZ+7hTwN9L8/QrNCE6TE false sufficient binding region:1-122|35s radiolabel:?-? mutation:83-83|mutation:83-83|flag tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P60903 uniprotkb:Q14527 intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym) psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:"MI:0096"(pull down) Oh et al. (2013) pubmed:23415230|imex:IM-20914 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6869729|imex:IM-20914-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205 refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 - - - figure legend:Fig. 2D|comment:The s100a10-SMARCA3 interaction was significantly increased by the addition of AnxA2 to the pull-down assay mixture|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/06/25 2014/10/16 rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 intact-crc:5382649AAA2BA657|rigid:ZXSnt/YpZ+7hTwN9L8/QrNCE6TE false glutathione s tranferase tag:?-? necessary binding region:26-39|35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)