#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O88778	uniprotkb:Q920M9	intact:EBI-2271660	intact:EBI-957514|uniprotkb:Q06984|ensembl:ENSRNOP00000020329	psi-mi:bsn_rat(display_long)|uniprotkb:Bsn(gene name)|psi-mi:Bsn(display_short)	psi-mi:siah1_rat(display_long)|uniprotkb:Siah1(gene name)|psi-mi:Siah1(display_short)|uniprotkb:Siah1a(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Waites et al. (2013)	pubmed:23403927|imex:IM-20946|mint:MINT-8431995	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8424241|mint:MINT-8432002|imex:IM-20946-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2223|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR030627|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O88778|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1990257"(piccolo-bassoon transport vesicle)|mint:MINT-8432004(identity)	ensembl:ENSRNOG00000015143(gene)|ensembl:ENSRNOT00000020329(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-RNO-373752|reactome:R-RNO-983168|refseq:XP_008770567.1|rgd:620449|refseq:NP_543181.2|dip:DIP-35686N|mint:MINT-8432005(identity)	-	-	-	comment:domino|comment:mint|figure legend:f8b f8c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/05/24	2014/10/16	rogid:7wqEryp1iWbXnosW6KDHacbGxpc10116	rogid:C7i3ubOqLVDW4MzmA6OLDZq2TM810116	intact-crc:3B2BE986AD34B5F5|rigid:8fNuPTSaAl45hQSzh6xe/pxHBfM	false	fusion protein:?-?(MINT-8432013)|binding-associated region:164-223(MINT-8432016)	myc tag:?-?(MINT-8432006)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9JKS6	uniprotkb:Q920M9	intact:EBI-2271602|uniprotkb:Q9JLT1	intact:EBI-957514|uniprotkb:Q06984|ensembl:ENSRNOP00000020329	psi-mi:pclo_rat(display_long)|uniprotkb:Pclo(gene name)|psi-mi:Pclo(display_short)|uniprotkb:Aczonin(gene name synonym)|uniprotkb:Multidomain presynaptic cytomatrix protein(gene name synonym)	psi-mi:siah1_rat(display_long)|uniprotkb:Siah1(gene name)|psi-mi:Siah1(display_short)|uniprotkb:Siah1a(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Waites et al. (2013)	pubmed:23403927|imex:IM-20946|mint:MINT-8431995	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8424285|mint:MINT-8432035|imex:IM-20946-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:69406|refseq:NP_001104267.1|refseq:NP_064483.1|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR042720|interpro:IPR030629|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9JKS6|interpro:IPR035892|interpro:IPR036034|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030133"(transport vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044316"(cone cell pedicle)|go:"GO:0044317"(rod spherule)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051036"(regulation of endosome size)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|rcsb pdb:1RH8|mint:MINT-8432037(identity)	ensembl:ENSRNOG00000015143(gene)|ensembl:ENSRNOT00000020329(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-RNO-373752|reactome:R-RNO-983168|refseq:XP_008770567.1|rgd:620449|refseq:NP_543181.2|dip:DIP-35686N|mint:MINT-8432044(identity)	-	-	-	comment:domino|comment:mint|figure legend:f8c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/05/24	2014/10/16	rogid:OnCRNzqU4rxi3dXGZHJ6mRcuLKs10116	rogid:C7i3ubOqLVDW4MzmA6OLDZq2TM810116	intact-crc:05F7BBCCEE4EC449|rigid:c4qx+/qkn1Pia4+Un6rN78XQzKU	false	binding-associated region:519-580(MINT-8432040)|fusion protein:?-?(MINT-8432038)	myc tag:?-?(MINT-8432045)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O88778	uniprotkb:Q920M9	intact:EBI-2271660	intact:EBI-957514|uniprotkb:Q06984|ensembl:ENSRNOP00000020329	psi-mi:bsn_rat(display_long)|uniprotkb:Bsn(gene name)|psi-mi:Bsn(display_short)	psi-mi:siah1_rat(display_long)|uniprotkb:Siah1(gene name)|psi-mi:Siah1(display_short)|uniprotkb:Siah1a(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Waites et al. (2013)	pubmed:23403927|imex:IM-20946|mint:MINT-8431995	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8424263|mint:MINT-8432020|imex:IM-20946-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2223|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR030627|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O88778|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1990257"(piccolo-bassoon transport vesicle)|mint:MINT-8432026(identity)	ensembl:ENSRNOG00000015143(gene)|ensembl:ENSRNOT00000020329(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-RNO-373752|reactome:R-RNO-983168|refseq:XP_008770567.1|rgd:620449|refseq:NP_543181.2|dip:DIP-35686N|mint:MINT-8432022(identity)	-	-	-	comment:domino|comment:mint|figure legend:f8b f8c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/05/24	2014/10/16	rogid:7wqEryp1iWbXnosW6KDHacbGxpc10116	rogid:C7i3ubOqLVDW4MzmA6OLDZq2TM810116	intact-crc:CB0DF33759FEAEFA|rigid:8fNuPTSaAl45hQSzh6xe/pxHBfM	false	binding-associated region:459-518(MINT-8432027)|fusion protein:?-?(MINT-8432030)	myc tag:?-?(MINT-8432023)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q920M9	uniprotkb:O88778	intact:EBI-957514|uniprotkb:Q06984|ensembl:ENSRNOP00000020329	intact:EBI-2271660	psi-mi:siah1_rat(display_long)|uniprotkb:Siah1(gene name)|psi-mi:Siah1(display_short)|uniprotkb:Siah1a(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:bsn_rat(display_long)|uniprotkb:Bsn(gene name)|psi-mi:Bsn(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Waites et al. (2013)	pubmed:23403927|imex:IM-20946|mint:MINT-8431995	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8424329|mint:MINT-8432124|imex:IM-20946-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000015143(gene)|ensembl:ENSRNOT00000020329(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-RNO-373752|reactome:R-RNO-983168|refseq:XP_008770567.1|rgd:620449|refseq:NP_543181.2|dip:DIP-35686N|mint:MINT-8432126(identity)	rgd:2223|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR030627|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O88778|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1990257"(piccolo-bassoon transport vesicle)|mint:MINT-8432130(identity)	-	-	-	comment:domino|comment:mint|figure legend:f8d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/05/24	2014/10/16	rogid:C7i3ubOqLVDW4MzmA6OLDZq2TM810116	rogid:7wqEryp1iWbXnosW6KDHacbGxpc10116	intact-crc:4EEA031D6B2AF49E|rigid:8fNuPTSaAl45hQSzh6xe/pxHBfM	false	binding-associated region:39-76(MINT-8432142)|green fluorescent protein tag:?-?(MINT-8432127)	fusion protein:?-?(MINT-8432131)|binding-associated region:164-223(MINT-8432133)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9JKS6	uniprotkb:Q920M9	intact:EBI-2271602|uniprotkb:Q9JLT1	intact:EBI-957514|uniprotkb:Q06984|ensembl:ENSRNOP00000020329	psi-mi:pclo_rat(display_long)|uniprotkb:Pclo(gene name)|psi-mi:Pclo(display_short)|uniprotkb:Aczonin(gene name synonym)|uniprotkb:Multidomain presynaptic cytomatrix protein(gene name synonym)	psi-mi:siah1_rat(display_long)|uniprotkb:Siah1(gene name)|psi-mi:Siah1(display_short)|uniprotkb:Siah1a(gene name synonym)|uniprotkb:Seven in absentia homolog 1(gene name synonym)|uniprotkb:Siah-1a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SIAH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Waites et al. (2013)	pubmed:23403927|imex:IM-20946|mint:MINT-8431995	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8424307|mint:MINT-8432050|imex:IM-20946-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:69406|refseq:NP_001104267.1|refseq:NP_064483.1|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR042720|interpro:IPR030629|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9JKS6|interpro:IPR035892|interpro:IPR036034|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030133"(transport vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044316"(cone cell pedicle)|go:"GO:0044317"(rod spherule)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051036"(regulation of endosome size)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|rcsb pdb:1RH8|mint:MINT-8432052(identity)	ensembl:ENSRNOG00000015143(gene)|ensembl:ENSRNOT00000020329(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-RNO-373752|reactome:R-RNO-983168|refseq:XP_008770567.1|rgd:620449|refseq:NP_543181.2|dip:DIP-35686N|mint:MINT-8432059(identity)	-	-	-	comment:domino|comment:mint|figure legend:f8c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2013/05/24	2014/10/16	rogid:OnCRNzqU4rxi3dXGZHJ6mRcuLKs10116	rogid:C7i3ubOqLVDW4MzmA6OLDZq2TM810116	intact-crc:AB6DC09577E7DC38|rigid:c4qx+/qkn1Pia4+Un6rN78XQzKU	false	binding-associated region:1007-1066(MINT-8432053)|fusion protein:?-?(MINT-8432056)	myc tag:?-?(MINT-8432060)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)