#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q75E93 uniprotkb:Q75FB3 intact:EBI-8416928|intact:MINT-8424073|ensemblfungi:AAS50554 intact:EBI-8845949|ensemblfungi:AAS50184 psi-mi:q75e93_ashgo(display_long)|uniprotkb:AGOS_AAR187C(orf name) psi-mi:q75fb3_ashgo(display_long)|uniprotkb:AGOS_AAL182W(orf name) psi-mi:"MI:0114"(x-ray crystallography) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8416923|mint:MINT-8424087|imex:IM-21688-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031550|refseq:NP_982730.1|interpro:IPR038496|mint:Q75E93|ensemblfungi:AAS50554(transcript)|ensemblfungi:AGOS_AAR187C(gene)|rcsb pdb:3ZIK|rcsb pdb:3ZIL|mint:MINT-8424089(identity) interpro:IPR024704|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|refseq:NP_982360.1|mint:Q75FB3|interpro:IPR036277|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|rcsb pdb:3ZIL|ensemblfungi:AAS50184(transcript)|ensemblfungi:AGOS_AAL182W(gene)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0061775"(cohesin loading activity)|go:"GO:0061776"(topological DNA co-entrapment activity)|go:"GO:0062022"("mitotic cohesin ssDNA (lagging strand) loading")|go:"GO:0071960"(maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR041741|mint:MINT-8424387(identity) rcsb pdb:3zil(primary-reference) - - figure legend:f5 st1 sf3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/04/03 2014/10/16 rogid:35o4vlKTuojYRXCbL7AIq/LOLAg284811 rogid:DCooHH9zCc8fZgxrK+CCbOHzGx4284811 intact-crc:2030AEADD64DBBA3|rigid:jcWm/mhJ31UoDHBrYJRe5K+wSlg false binding-associated region:184-561(MINT-8424290) binding-associated region:159-163(MINT-8424483) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q75E93 uniprotkb:Q757M9 intact:EBI-8416928|intact:MINT-8424073|ensemblfungi:AAS50554 intact:EBI-8847086|ensemblfungi:AAS52678 psi-mi:q75e93_ashgo(display_long)|uniprotkb:AGOS_AAR187C(orf name) psi-mi:q757m9_ashgo(display_long)|uniprotkb:AGOS_AEL007W(orf name) psi-mi:"MI:0081"(peptide array) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8847095|mint:MINT-8424087|imex:IM-21688-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031550|refseq:NP_982730.1|interpro:IPR038496|mint:Q75E93|ensemblfungi:AAS50554(transcript)|ensemblfungi:AGOS_AAR187C(gene)|rcsb pdb:3ZIK|rcsb pdb:3ZIL|mint:MINT-8424089(identity) interpro:IPR023093|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|refseq:NP_984854.2|mint:Q757M9|interpro:IPR036390|interpro:IPR039781|ensemblfungi:AAS52678(transcript)|ensemblfungi:AGOS_AEL007W(gene)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|mint:MINT-8424387(identity) - - - figure legend:f3a sf2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/04/03 2014/10/16 rogid:35o4vlKTuojYRXCbL7AIq/LOLAg284811 rogid:rzrpX2PVE3Bi40t5wwsP7IBkfSA284811 intact-crc:E2C866189DB47904|rigid:3OAoxIu6ZHJO4QcxFVNwonXQ4v0 false binding-associated region:184-561(MINT-8424290) binding-associated region:139-168(MINT-8424483) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q75E93 uniprotkb:Q75FB3 intact:EBI-8416928|intact:MINT-8424073|ensemblfungi:AAS50554 intact:EBI-8845949|ensemblfungi:AAS50184 psi-mi:q75e93_ashgo(display_long)|uniprotkb:AGOS_AAR187C(orf name) psi-mi:q75fb3_ashgo(display_long)|uniprotkb:AGOS_AAL182W(orf name) psi-mi:"MI:0081"(peptide array) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846011|mint:MINT-8424087|imex:IM-21688-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031550|refseq:NP_982730.1|interpro:IPR038496|mint:Q75E93|ensemblfungi:AAS50554(transcript)|ensemblfungi:AGOS_AAR187C(gene)|rcsb pdb:3ZIK|rcsb pdb:3ZIL|mint:MINT-8424089(identity) interpro:IPR024704|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|refseq:NP_982360.1|mint:Q75FB3|interpro:IPR036277|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|rcsb pdb:3ZIL|ensemblfungi:AAS50184(transcript)|ensemblfungi:AGOS_AAL182W(gene)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0061775"(cohesin loading activity)|go:"GO:0061776"(topological DNA co-entrapment activity)|go:"GO:0062022"("mitotic cohesin ssDNA (lagging strand) loading")|go:"GO:0071960"(maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR041741|mint:MINT-8424387(identity) - - - figure legend:f3a sf2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/04/03 2014/10/16 rogid:35o4vlKTuojYRXCbL7AIq/LOLAg284811 rogid:DCooHH9zCc8fZgxrK+CCbOHzGx4284811 intact-crc:03AC43DB12F20249|rigid:jcWm/mhJ31UoDHBrYJRe5K+wSlg false binding-associated region:184-561(MINT-8424290) binding-associated region:1045-1066(MINT-8424483) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q75E93 uniprotkb:Q75FB3 intact:EBI-8416928|intact:MINT-8424073|ensemblfungi:AAS50554 intact:EBI-8845949|ensemblfungi:AAS50184 psi-mi:q75e93_ashgo(display_long)|uniprotkb:AGOS_AAR187C(orf name) psi-mi:q75fb3_ashgo(display_long)|uniprotkb:AGOS_AAL182W(orf name) psi-mi:"MI:0081"(peptide array) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8845868|mint:MINT-8424087|imex:IM-21688-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031550|refseq:NP_982730.1|interpro:IPR038496|mint:Q75E93|ensemblfungi:AAS50554(transcript)|ensemblfungi:AGOS_AAR187C(gene)|rcsb pdb:3ZIK|rcsb pdb:3ZIL|mint:MINT-8424089(identity) interpro:IPR024704|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|refseq:NP_982360.1|mint:Q75FB3|interpro:IPR036277|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|rcsb pdb:3ZIL|ensemblfungi:AAS50184(transcript)|ensemblfungi:AGOS_AAL182W(gene)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0061775"(cohesin loading activity)|go:"GO:0061776"(topological DNA co-entrapment activity)|go:"GO:0062022"("mitotic cohesin ssDNA (lagging strand) loading")|go:"GO:0071960"(maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR041741|mint:MINT-8424387(identity) - - - figure legend:f3a sf2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/04/03 2014/10/16 rogid:35o4vlKTuojYRXCbL7AIq/LOLAg284811 rogid:DCooHH9zCc8fZgxrK+CCbOHzGx4284811 intact-crc:E3E8888B77EB9893|rigid:jcWm/mhJ31UoDHBrYJRe5K+wSlg false binding-associated region:184-561(MINT-8424290) binding-associated region:101-112(MINT-8424483) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q75E93 uniprotkb:Q757M9 intact:EBI-8416928|intact:MINT-8424073|ensemblfungi:AAS50554 intact:EBI-8847086|ensemblfungi:AAS52678 psi-mi:q75e93_ashgo(display_long)|uniprotkb:AGOS_AAR187C(orf name) psi-mi:q757m9_ashgo(display_long)|uniprotkb:AGOS_AEL007W(orf name) psi-mi:"MI:0081"(peptide array) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8847110|imex:IM-21688-20|mint:MINT-8424087 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031550|refseq:NP_982730.1|interpro:IPR038496|mint:Q75E93|ensemblfungi:AAS50554(transcript)|ensemblfungi:AGOS_AAR187C(gene)|rcsb pdb:3ZIK|rcsb pdb:3ZIL|mint:MINT-8424089(identity) interpro:IPR023093|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|refseq:NP_984854.2|mint:Q757M9|interpro:IPR036390|interpro:IPR039781|ensemblfungi:AAS52678(transcript)|ensemblfungi:AGOS_AEL007W(gene)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|mint:MINT-8424387(identity) - - - figure legend:f3a sf2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/04/03 2014/10/16 rogid:35o4vlKTuojYRXCbL7AIq/LOLAg284811 rogid:rzrpX2PVE3Bi40t5wwsP7IBkfSA284811 intact-crc:0EFD9145D6422035|rigid:3OAoxIu6ZHJO4QcxFVNwonXQ4v0 false binding-associated region:184-561(MINT-8424290) binding-associated region:391-428(MINT-8424483) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q75E93 uniprotkb:Q757M9 intact:EBI-8416928|intact:MINT-8424073|ensemblfungi:AAS50554 intact:EBI-8847086|ensemblfungi:AAS52678 psi-mi:q75e93_ashgo(display_long)|uniprotkb:AGOS_AAR187C(orf name) psi-mi:q757m9_ashgo(display_long)|uniprotkb:AGOS_AEL007W(orf name) psi-mi:"MI:0081"(peptide array) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8847070|mint:MINT-8424087|imex:IM-21688-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031550|refseq:NP_982730.1|interpro:IPR038496|mint:Q75E93|ensemblfungi:AAS50554(transcript)|ensemblfungi:AGOS_AAR187C(gene)|rcsb pdb:3ZIK|rcsb pdb:3ZIL|mint:MINT-8424089(identity) interpro:IPR023093|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|refseq:NP_984854.2|mint:Q757M9|interpro:IPR036390|interpro:IPR039781|ensemblfungi:AAS52678(transcript)|ensemblfungi:AGOS_AEL007W(gene)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|mint:MINT-8424387(identity) - - - figure legend:f3a sf2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/04/03 2014/10/16 rogid:35o4vlKTuojYRXCbL7AIq/LOLAg284811 rogid:rzrpX2PVE3Bi40t5wwsP7IBkfSA284811 intact-crc:E3EA588B77EB9893|rigid:3OAoxIu6ZHJO4QcxFVNwonXQ4v0 false binding-associated region:184-561(MINT-8424290) binding-associated region:88-120(MINT-8424483) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q75E93 uniprotkb:Q75FB3 intact:EBI-8416928|intact:MINT-8424073|ensemblfungi:AAS50554 intact:EBI-8845949|ensemblfungi:AAS50184 psi-mi:q75e93_ashgo(display_long)|uniprotkb:AGOS_AAR187C(orf name) psi-mi:q75fb3_ashgo(display_long)|uniprotkb:AGOS_AAL182W(orf name) psi-mi:"MI:0081"(peptide array) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8845974|mint:MINT-8424087|imex:IM-21688-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031550|refseq:NP_982730.1|interpro:IPR038496|mint:Q75E93|ensemblfungi:AAS50554(transcript)|ensemblfungi:AGOS_AAR187C(gene)|rcsb pdb:3ZIK|rcsb pdb:3ZIL|mint:MINT-8424089(identity) interpro:IPR024704|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|refseq:NP_982360.1|mint:Q75FB3|interpro:IPR036277|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|rcsb pdb:3ZIL|ensemblfungi:AAS50184(transcript)|ensemblfungi:AGOS_AAL182W(gene)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0061775"(cohesin loading activity)|go:"GO:0061776"(topological DNA co-entrapment activity)|go:"GO:0062022"("mitotic cohesin ssDNA (lagging strand) loading")|go:"GO:0071960"(maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR041741|mint:MINT-8424387(identity) - - - figure legend:f3a sf2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/04/03 2014/10/16 rogid:35o4vlKTuojYRXCbL7AIq/LOLAg284811 rogid:DCooHH9zCc8fZgxrK+CCbOHzGx4284811 intact-crc:90DD2219F9ACC2B8|rigid:jcWm/mhJ31UoDHBrYJRe5K+wSlg false binding-associated region:184-561(MINT-8424290) binding-associated region:133-163(MINT-8424483) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q75E93 uniprotkb:Q75FB3 intact:EBI-8416928|intact:MINT-8424073|ensemblfungi:AAS50554 intact:EBI-8845949|ensemblfungi:AAS50184 psi-mi:q75e93_ashgo(display_long)|uniprotkb:AGOS_AAR187C(orf name) psi-mi:q75fb3_ashgo(display_long)|uniprotkb:AGOS_AAL182W(orf name) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846232|imex:IM-21688-5|mint:MINT-8424087 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031550|refseq:NP_982730.1|interpro:IPR038496|mint:Q75E93|ensemblfungi:AAS50554(transcript)|ensemblfungi:AGOS_AAR187C(gene)|rcsb pdb:3ZIK|rcsb pdb:3ZIL|mint:MINT-8424089(identity) interpro:IPR024704|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|refseq:NP_982360.1|mint:Q75FB3|interpro:IPR036277|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|rcsb pdb:3ZIL|ensemblfungi:AAS50184(transcript)|ensemblfungi:AGOS_AAL182W(gene)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0061775"(cohesin loading activity)|go:"GO:0061776"(topological DNA co-entrapment activity)|go:"GO:0062022"("mitotic cohesin ssDNA (lagging strand) loading")|go:"GO:0071960"(maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR041741|mint:MINT-8424387(identity) - - - figure legend:f4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:126.0x10^-6(molar) 2013/04/03 2014/10/16 rogid:35o4vlKTuojYRXCbL7AIq/LOLAg284811 rogid:DCooHH9zCc8fZgxrK+CCbOHzGx4284811 intact-crc:FFF5A9C9134E96CE|rigid:jcWm/mhJ31UoDHBrYJRe5K+wSlg false binding-associated region:184-561(MINT-8424290) binding-associated region:101-112(MINT-8424483) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q75E93 uniprotkb:Q75FB3 intact:EBI-8416928|intact:MINT-8424073|ensemblfungi:AAS50554 intact:EBI-8845949|ensemblfungi:AAS50184 psi-mi:q75e93_ashgo(display_long)|uniprotkb:AGOS_AAR187C(orf name) psi-mi:q75fb3_ashgo(display_long)|uniprotkb:AGOS_AAL182W(orf name) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846266|imex:IM-21688-7|mint:MINT-8424087 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031550|refseq:NP_982730.1|interpro:IPR038496|mint:Q75E93|ensemblfungi:AAS50554(transcript)|ensemblfungi:AGOS_AAR187C(gene)|rcsb pdb:3ZIK|rcsb pdb:3ZIL|mint:MINT-8424089(identity) interpro:IPR024704|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|refseq:NP_982360.1|mint:Q75FB3|interpro:IPR036277|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|rcsb pdb:3ZIL|ensemblfungi:AAS50184(transcript)|ensemblfungi:AGOS_AAL182W(gene)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0061775"(cohesin loading activity)|go:"GO:0061776"(topological DNA co-entrapment activity)|go:"GO:0062022"("mitotic cohesin ssDNA (lagging strand) loading")|go:"GO:0071960"(maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR041741|mint:MINT-8424387(identity) - - - figure legend:f4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:120.0x10^-6(molar) 2013/04/03 2014/10/16 rogid:35o4vlKTuojYRXCbL7AIq/LOLAg284811 rogid:DCooHH9zCc8fZgxrK+CCbOHzGx4284811 intact-crc:7E1DA6D48647EBC1|rigid:jcWm/mhJ31UoDHBrYJRe5K+wSlg false binding-associated region:184-561(MINT-8424290) binding-associated region:133-163(MINT-8424483) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q75E93 uniprotkb:Q75FB3 intact:EBI-8416928|intact:MINT-8424073|ensemblfungi:AAS50554 intact:EBI-8845949|ensemblfungi:AAS50184 psi-mi:q75e93_ashgo(display_long)|uniprotkb:AGOS_AAR187C(orf name) psi-mi:q75fb3_ashgo(display_long)|uniprotkb:AGOS_AAL182W(orf name) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846248|imex:IM-21688-6|mint:MINT-8424087 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031550|refseq:NP_982730.1|interpro:IPR038496|mint:Q75E93|ensemblfungi:AAS50554(transcript)|ensemblfungi:AGOS_AAR187C(gene)|rcsb pdb:3ZIK|rcsb pdb:3ZIL|mint:MINT-8424089(identity) interpro:IPR024704|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|refseq:NP_982360.1|mint:Q75FB3|interpro:IPR036277|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|rcsb pdb:3ZIL|ensemblfungi:AAS50184(transcript)|ensemblfungi:AGOS_AAL182W(gene)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0061775"(cohesin loading activity)|go:"GO:0061776"(topological DNA co-entrapment activity)|go:"GO:0062022"("mitotic cohesin ssDNA (lagging strand) loading")|go:"GO:0071960"(maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR041741|mint:MINT-8424387(identity) - - - figure legend:f4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:275.0x10^-6(molar) 2013/04/03 2014/10/16 rogid:35o4vlKTuojYRXCbL7AIq/LOLAg284811 rogid:DCooHH9zCc8fZgxrK+CCbOHzGx4284811 intact-crc:A2ADBA7B933595AD|rigid:jcWm/mhJ31UoDHBrYJRe5K+wSlg false binding-associated region:184-561(MINT-8424290) binding-associated region:101-112(MINT-8424483)|monoacetylated residue:108-108 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q75E93 uniprotkb:Q75FB3 intact:EBI-8416928|intact:MINT-8424073|ensemblfungi:AAS50554 intact:EBI-8845949|ensemblfungi:AAS50184 psi-mi:q75e93_ashgo(display_long)|uniprotkb:AGOS_AAR187C(orf name) psi-mi:q75fb3_ashgo(display_long)|uniprotkb:AGOS_AAL182W(orf name) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") taxid:284811(ashgo)|taxid:284811("Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846284|imex:IM-21688-8|mint:MINT-8424087 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031550|refseq:NP_982730.1|interpro:IPR038496|mint:Q75E93|ensemblfungi:AAS50554(transcript)|ensemblfungi:AGOS_AAR187C(gene)|rcsb pdb:3ZIK|rcsb pdb:3ZIL|mint:MINT-8424089(identity) interpro:IPR024704|interpro:IPR027417|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|refseq:NP_982360.1|mint:Q75FB3|interpro:IPR036277|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|rcsb pdb:3ZIL|ensemblfungi:AAS50184(transcript)|ensemblfungi:AGOS_AAL182W(gene)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0005524"(ATP binding)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0061775"(cohesin loading activity)|go:"GO:0061776"(topological DNA co-entrapment activity)|go:"GO:0062022"("mitotic cohesin ssDNA (lagging strand) loading")|go:"GO:0071960"(maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR041741|mint:MINT-8424387(identity) - - - figure legend:f4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:154.0x10^-6(molar) 2013/04/03 2014/10/16 rogid:35o4vlKTuojYRXCbL7AIq/LOLAg284811 rogid:DCooHH9zCc8fZgxrK+CCbOHzGx4284811 intact-crc:7302601804C180D3|rigid:jcWm/mhJ31UoDHBrYJRe5K+wSlg false binding-associated region:184-561(MINT-8424290) binding-associated region:1045-1066(MINT-8424483) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q99359 uniprotkb:P47037 intact:EBI-2082336|uniprotkb:D6VS00|ensemblfungi:YDR014W intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:rad61_yeast(display_long)|uniprotkb:RAD61(gene name)|psi-mi:RAD61(display_short)|uniprotkb:Radiation sensitivity protein 61(gene name synonym)|uniprotkb:PZB647(orf name)|uniprotkb:YDR014W(locus name) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846931|imex:IM-21688-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002421|refseq:NP_010297.1|interpro:IPR031550|interpro:IPR038496|mint:Q99359|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0140588"(chromatin looping)|go:"GO:1902340"(negative regulation of chromosome condensation)|go:"GO:1905339"(positive regulation of cohesin unloading)|ensemblfungi:YDR014W(gene)|ensemblfungi:YDR014W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0034183"(negative regulation of maintenance of mitotic sister chromatid cohesion) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - - crc64:B152D88F7780341F figure legend:t1 sf2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:77.0x10^-9(molar) 2013/04/03 2014/10/16 rogid:F9Qg9MxjD+pUILRGkAwWmf9Ftjo559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:1566E334A3F8FF40|rigid:rDh/DSe+ynrxJ0hzo3f3qGksZeY false mutation decreasing interaction:493-493,622-622,577-577|binding-associated region:259-647 binding-associated region:1-190,1047-1230|glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99359 uniprotkb:P47037 intact:EBI-2082336|uniprotkb:D6VS00|ensemblfungi:YDR014W intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:rad61_yeast(display_long)|uniprotkb:RAD61(gene name)|psi-mi:RAD61(display_short)|uniprotkb:Radiation sensitivity protein 61(gene name synonym)|uniprotkb:PZB647(orf name)|uniprotkb:YDR014W(locus name) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846314|imex:IM-21688-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002421|refseq:NP_010297.1|interpro:IPR031550|interpro:IPR038496|mint:Q99359|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0140588"(chromatin looping)|go:"GO:1902340"(negative regulation of chromosome condensation)|go:"GO:1905339"(positive regulation of cohesin unloading)|ensemblfungi:YDR014W(gene)|ensemblfungi:YDR014W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0034183"(negative regulation of maintenance of mitotic sister chromatid cohesion) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - - crc64:B152D88F7780341F figure legend:t1 sf2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:47.0x10^-9(molar) 2013/04/03 2014/10/16 rogid:F9Qg9MxjD+pUILRGkAwWmf9Ftjo559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:9D7B70D332E342C1|rigid:rDh/DSe+ynrxJ0hzo3f3qGksZeY false binding-associated region:259-647 glutathione s tranferase tag:?-?|binding-associated region:1-190,1047-1230 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99359 uniprotkb:P47037 intact:EBI-2082336|uniprotkb:D6VS00|ensemblfungi:YDR014W intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:rad61_yeast(display_long)|uniprotkb:RAD61(gene name)|psi-mi:RAD61(display_short)|uniprotkb:Radiation sensitivity protein 61(gene name synonym)|uniprotkb:PZB647(orf name)|uniprotkb:YDR014W(locus name) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846332|imex:IM-21688-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002421|refseq:NP_010297.1|interpro:IPR031550|interpro:IPR038496|mint:Q99359|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0140588"(chromatin looping)|go:"GO:1902340"(negative regulation of chromosome condensation)|go:"GO:1905339"(positive regulation of cohesin unloading)|ensemblfungi:YDR014W(gene)|ensemblfungi:YDR014W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0034183"(negative regulation of maintenance of mitotic sister chromatid cohesion) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - - crc64:B152D88F7780341F figure legend:t1 sf2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:88.0x10^-9(molar) 2013/04/03 2014/10/16 rogid:F9Qg9MxjD+pUILRGkAwWmf9Ftjo559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:51697A1AB321CE68|rigid:rDh/DSe+ynrxJ0hzo3f3qGksZeY false binding-associated region:259-647 glutathione s tranferase tag:?-?|binding-associated region:1-190,1047-1230|mutation decreasing interaction:113-113,112-112 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99359 uniprotkb:P47037 intact:EBI-2082336|uniprotkb:D6VS00|ensemblfungi:YDR014W intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:rad61_yeast(display_long)|uniprotkb:RAD61(gene name)|psi-mi:RAD61(display_short)|uniprotkb:Radiation sensitivity protein 61(gene name synonym)|uniprotkb:PZB647(orf name)|uniprotkb:YDR014W(locus name) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846887|imex:IM-21688-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002421|refseq:NP_010297.1|interpro:IPR031550|interpro:IPR038496|mint:Q99359|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0140588"(chromatin looping)|go:"GO:1902340"(negative regulation of chromosome condensation)|go:"GO:1905339"(positive regulation of cohesin unloading)|ensemblfungi:YDR014W(gene)|ensemblfungi:YDR014W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0034183"(negative regulation of maintenance of mitotic sister chromatid cohesion) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - - crc64:B152D88F7780341F figure legend:t1 sf2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:126.0x10^-9(molar) 2013/04/03 2014/10/16 rogid:F9Qg9MxjD+pUILRGkAwWmf9Ftjo559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:E305408477D80119|rigid:rDh/DSe+ynrxJ0hzo3f3qGksZeY false binding-associated region:259-647|mutation decreasing interaction:493-493,622-622 glutathione s tranferase tag:?-?|binding-associated region:1-190,1047-1230 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47037 uniprotkb:Q99359 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-2082336|uniprotkb:D6VS00|ensemblfungi:YDR014W psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:rad61_yeast(display_long)|uniprotkb:RAD61(gene name)|psi-mi:RAD61(display_short)|uniprotkb:Radiation sensitivity protein 61(gene name synonym)|uniprotkb:PZB647(orf name)|uniprotkb:YDR014W(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846870|imex:IM-21688-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 sgd:S000002421|refseq:NP_010297.1|interpro:IPR031550|interpro:IPR038496|mint:Q99359|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0140588"(chromatin looping)|go:"GO:1902340"(negative regulation of chromosome condensation)|go:"GO:1905339"(positive regulation of cohesin unloading)|ensemblfungi:YDR014W(gene)|ensemblfungi:YDR014W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0034183"(negative regulation of maintenance of mitotic sister chromatid cohesion) - crc64:B152D88F7780341F - figure legend:t1 sf2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:102.0x10^-9(molar) 2013/04/03 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:F9Qg9MxjD+pUILRGkAwWmf9Ftjo559292 intact-crc:D83A1FF12F4F8D3B|rigid:rDh/DSe+ynrxJ0hzo3f3qGksZeY false binding-associated region:1-190,1047-1230|glutathione s tranferase tag:?-?|mutation decreasing interaction:163-163,166-166 binding-associated region:259-647 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99359 uniprotkb:P47037 intact:EBI-2082336|uniprotkb:D6VS00|ensemblfungi:YDR014W intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:rad61_yeast(display_long)|uniprotkb:RAD61(gene name)|psi-mi:RAD61(display_short)|uniprotkb:Radiation sensitivity protein 61(gene name synonym)|uniprotkb:PZB647(orf name)|uniprotkb:YDR014W(locus name) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846993|imex:IM-21688-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002421|refseq:NP_010297.1|interpro:IPR031550|interpro:IPR038496|mint:Q99359|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0140588"(chromatin looping)|go:"GO:1902340"(negative regulation of chromosome condensation)|go:"GO:1905339"(positive regulation of cohesin unloading)|ensemblfungi:YDR014W(gene)|ensemblfungi:YDR014W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0034183"(negative regulation of maintenance of mitotic sister chromatid cohesion) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - - crc64:B152D88F7780341F figure legend:t1 sf2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:167.0x10^-9(molar) 2013/04/03 2014/10/16 rogid:F9Qg9MxjD+pUILRGkAwWmf9Ftjo559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:D9313C559E6AC95D|rigid:rDh/DSe+ynrxJ0hzo3f3qGksZeY false mutation decreasing interaction:272-272,271-271|binding-associated region:259-647 binding-associated region:1-190,1047-1230|glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99359 uniprotkb:P47037 intact:EBI-2082336|uniprotkb:D6VS00|ensemblfungi:YDR014W intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:rad61_yeast(display_long)|uniprotkb:RAD61(gene name)|psi-mi:RAD61(display_short)|uniprotkb:Radiation sensitivity protein 61(gene name synonym)|uniprotkb:PZB647(orf name)|uniprotkb:YDR014W(locus name) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846965|imex:IM-21688-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002421|refseq:NP_010297.1|interpro:IPR031550|interpro:IPR038496|mint:Q99359|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0140588"(chromatin looping)|go:"GO:1902340"(negative regulation of chromosome condensation)|go:"GO:1905339"(positive regulation of cohesin unloading)|ensemblfungi:YDR014W(gene)|ensemblfungi:YDR014W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0034183"(negative regulation of maintenance of mitotic sister chromatid cohesion) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - - crc64:B152D88F7780341F figure legend:t1 sf2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:82.0x10^-9(molar) 2013/04/03 2014/10/16 rogid:F9Qg9MxjD+pUILRGkAwWmf9Ftjo559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:BE45E51AD81F77C6|rigid:rDh/DSe+ynrxJ0hzo3f3qGksZeY false binding-associated region:259-647|mutation decreasing interaction:493-493,622-622,532-532 binding-associated region:1-190,1047-1230|glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47037 uniprotkb:Q99359 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-2082336|uniprotkb:D6VS00|ensemblfungi:YDR014W psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:rad61_yeast(display_long)|uniprotkb:RAD61(gene name)|psi-mi:RAD61(display_short)|uniprotkb:Radiation sensitivity protein 61(gene name synonym)|uniprotkb:PZB647(orf name)|uniprotkb:YDR014W(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8847030|imex:IM-21688-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 sgd:S000002421|refseq:NP_010297.1|interpro:IPR031550|interpro:IPR038496|mint:Q99359|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0140588"(chromatin looping)|go:"GO:1902340"(negative regulation of chromosome condensation)|go:"GO:1905339"(positive regulation of cohesin unloading)|ensemblfungi:YDR014W(gene)|ensemblfungi:YDR014W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0034183"(negative regulation of maintenance of mitotic sister chromatid cohesion) - crc64:B152D88F7780341F - figure legend:t1 sf2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:200.0x10^-9(molar) 2013/04/03 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:F9Qg9MxjD+pUILRGkAwWmf9Ftjo559292 intact-crc:6A84558699A300D2|rigid:rDh/DSe+ynrxJ0hzo3f3qGksZeY false binding-associated region:1-190,1047-1230|glutathione s tranferase tag:?-? mutation decreasing interaction:376-376,377-377,383-383,382-382|binding-associated region:259-647 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99359 uniprotkb:P47037 intact:EBI-2082336|uniprotkb:D6VS00|ensemblfungi:YDR014W intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:rad61_yeast(display_long)|uniprotkb:RAD61(gene name)|psi-mi:RAD61(display_short)|uniprotkb:Radiation sensitivity protein 61(gene name synonym)|uniprotkb:PZB647(orf name)|uniprotkb:YDR014W(locus name) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Chatterjee et al. (2013) pubmed:23395900|imex:IM-21688|mint:MINT-8424023 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8846708|imex:IM-21688-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002421|refseq:NP_010297.1|interpro:IPR031550|interpro:IPR038496|mint:Q99359|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0140588"(chromatin looping)|go:"GO:1902340"(negative regulation of chromosome condensation)|go:"GO:1905339"(positive regulation of cohesin unloading)|ensemblfungi:YDR014W(gene)|ensemblfungi:YDR014W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0034183"(negative regulation of maintenance of mitotic sister chromatid cohesion) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - - crc64:B152D88F7780341F figure legend:t1 sf2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:104.0x10^-9(molar) 2013/04/03 2014/10/16 rogid:F9Qg9MxjD+pUILRGkAwWmf9Ftjo559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:4E8AF6C96CF63AE2|rigid:rDh/DSe+ynrxJ0hzo3f3qGksZeY false binding-associated region:259-647 binding-associated region:1-190,1047-1230|mutation decreasing interaction:163-163,166-166,168-168|glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)