#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:G5EF47 uniprotkb:G5ECF1 intact:EBI-6919756|ensemblmetazoa:Y73B6A.4.1 intact:EBI-6919737|ensemblmetazoa:W02D3.8.1 psi-mi:g5ef47_caeel(display_long)|uniprotkb:smg-7(gene name)|psi-mi:smg-7(display_short)|uniprotkb:CELE_Y73B6A.4(orf name)|uniprotkb:Y73B6A.4(orf name) psi-mi:g5ecf1_caeel(display_long)|uniprotkb:smg-5(gene name)|psi-mi:smg-5(display_short)|uniprotkb:CELE_W02D3.8(orf name)|uniprotkb:W02D3.8(orf name) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6920082|imex:IM-21082-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004885(gene)|ensemblmetazoa:Y73B6A.4.1(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070034"(telomerase RNA binding)|refseq:NP_501033.1|interpro:IPR018834|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:3ZHE|wormbase:Y73B6A.4 interpro:IPR011990(Tetratricopeptide-like helical)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016246"(RNA interference)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030538"(embryonic genitalia morphogenesis)|go:"GO:0034660"(ncRNA metabolic process)|go:"GO:0051721"(protein phosphatase 2A binding)|ensemblmetazoa:WBGene00004883(gene)|ensemblmetazoa:W02D3.8.1(transcript)|refseq:NP_491929.1|rcsb pdb:3ZHE|wormbase:W02D3.8|interpro:IPR002716(PilT protein, N-terminal) - - - figure legend:Figure 3B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/06 2014/10/16 rogid:qF+MjAHXTZxmT7fwSGfPiufV26s6239 rogid:sNbOuUztL2DZdEtpruQdkcMjV946239 intact-crc:CF37B13D419762B5|rigid:WH3n6E5O/wwPZCElZmtuY0rDhY4 false necessary binding region:90-90|v5 tag:?-? necessary binding region:94-94|ha tag:?-?|necessary binding region:116-116|necessary binding region:91-91 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92540 uniprotkb:Q9UPR3 intact:EBI-719830|uniprotkb:Q5T1Q0|uniprotkb:Q6PIE0|uniprotkb:Q7Z7H9|uniprotkb:Q8IXC1|uniprotkb:Q8IXC2|intact:EBI-28984519|ensembl:ENSP00000340766|uniprotkb:B4DRB2|uniprotkb:E9PCI0|uniprotkb:E9PEH2 intact:EBI-3400861|ensembl:ENSP00000355261|uniprotkb:Q5QJE7|uniprotkb:Q659C7|uniprotkb:Q8IXC0|uniprotkb:Q8IY09|uniprotkb:Q96IJ7|uniprotkb:D3DVB7 psi-mi:smg7_human(display_long)|uniprotkb:SMG-7 homolog(gene name synonym)|uniprotkb:EST1-like protein C(gene name synonym)|uniprotkb:SMG7(gene name)|psi-mi:SMG7(display_short)|uniprotkb:KIAA0250(gene name synonym)|uniprotkb:C1orf16(gene name synonym)|uniprotkb:EST1C(gene name synonym) psi-mi:smg5_human(display_long)|uniprotkb:SMG5(gene name)|psi-mi:SMG5(display_short)|uniprotkb:EST1B(gene name synonym)|uniprotkb:KIAA1089(gene name synonym)|uniprotkb:EST1-like protein B(gene name synonym)|uniprotkb:LPTS-RP1(gene name synonym)|uniprotkb:LPTS-interacting protein(gene name synonym)|uniprotkb:SMG-5 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6920429|imex:IM-21082-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167532.1|refseq:NP_775179.1|refseq:NP_963862.1|refseq:NP_963863.2|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q92540|rcsb pdb:1YA0|reactome:R-HSA-975957|ensembl:ENSG00000116698(gene)|ensembl:ENST00000347615(transcript)|ensembl:ENSP00000340766|ensembl:ENST00000507469|ensembl:ENSP00000425133|ensembl:ENST00000508461|ensembl:ENSP00000426915|ensembl:ENST00000515829|ensembl:ENSP00000421358 ensembl:ENSG00000198952(gene)|ensembl:ENST00000361813(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q9UPR3|rcsb pdb:2HWY|reactome:R-HSA-975957|interpro:IPR002716(PilT protein, N-terminal)|refseq:NP_056142.2 - - - figure legend:Figure 3C, 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/06 2015/06/25 rogid:HgJSiXiQQT33P4AyLMd2pmFB/VM9606 rogid:HeKpTzaiwDkA7b7lvjiODr7yuxA9606 intact-crc:965E75E5DB5B264C|rigid:jwJvrasn9kJgGZ8R0yp5u6jqT5Y false mutation disrupting interaction strength:100-100|mutation disrupting interaction strength:103-103|ha tag:?-? necessary binding region:120-120|v5 tag:c-c|sbp:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92540 uniprotkb:Q9UPR3 intact:EBI-719830|uniprotkb:Q5T1Q0|uniprotkb:Q6PIE0|uniprotkb:Q7Z7H9|uniprotkb:Q8IXC1|uniprotkb:Q8IXC2|intact:EBI-28984519|ensembl:ENSP00000340766|uniprotkb:B4DRB2|uniprotkb:E9PCI0|uniprotkb:E9PEH2 intact:EBI-3400861|ensembl:ENSP00000355261|uniprotkb:Q5QJE7|uniprotkb:Q659C7|uniprotkb:Q8IXC0|uniprotkb:Q8IY09|uniprotkb:Q96IJ7|uniprotkb:D3DVB7 psi-mi:smg7_human(display_long)|uniprotkb:SMG-7 homolog(gene name synonym)|uniprotkb:EST1-like protein C(gene name synonym)|uniprotkb:SMG7(gene name)|psi-mi:SMG7(display_short)|uniprotkb:KIAA0250(gene name synonym)|uniprotkb:C1orf16(gene name synonym)|uniprotkb:EST1C(gene name synonym) psi-mi:smg5_human(display_long)|uniprotkb:SMG5(gene name)|psi-mi:SMG5(display_short)|uniprotkb:EST1B(gene name synonym)|uniprotkb:KIAA1089(gene name synonym)|uniprotkb:EST1-like protein B(gene name synonym)|uniprotkb:LPTS-RP1(gene name synonym)|uniprotkb:LPTS-interacting protein(gene name synonym)|uniprotkb:SMG-5 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6920928|imex:IM-21082-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167532.1|refseq:NP_775179.1|refseq:NP_963862.1|refseq:NP_963863.2|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q92540|rcsb pdb:1YA0|reactome:R-HSA-975957|ensembl:ENSG00000116698(gene)|ensembl:ENST00000347615(transcript)|ensembl:ENSP00000340766|ensembl:ENST00000507469|ensembl:ENSP00000425133|ensembl:ENST00000508461|ensembl:ENSP00000426915|ensembl:ENST00000515829|ensembl:ENSP00000421358 ensembl:ENSG00000198952(gene)|ensembl:ENST00000361813(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q9UPR3|rcsb pdb:2HWY|reactome:R-HSA-975957|interpro:IPR002716(PilT protein, N-terminal)|refseq:NP_056142.2 - - - figure legend:Figure 6A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/06 2014/10/16 rogid:HgJSiXiQQT33P4AyLMd2pmFB/VM9606 rogid:HeKpTzaiwDkA7b7lvjiODr7yuxA9606 intact-crc:B064651C94EA7785|rigid:jwJvrasn9kJgGZ8R0yp5u6jqT5Y false yellow fluorescent protein tag:?-? mutation disrupting interaction strength:120-120|v5 tag:c-c|sbp:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92540 uniprotkb:Q92900 intact:EBI-719830|uniprotkb:Q5T1Q0|uniprotkb:Q6PIE0|uniprotkb:Q7Z7H9|uniprotkb:Q8IXC1|uniprotkb:Q8IXC2|intact:EBI-28984519|ensembl:ENSP00000340766|uniprotkb:B4DRB2|uniprotkb:E9PCI0|uniprotkb:E9PEH2 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:smg7_human(display_long)|uniprotkb:SMG-7 homolog(gene name synonym)|uniprotkb:EST1-like protein C(gene name synonym)|uniprotkb:SMG7(gene name)|psi-mi:SMG7(display_short)|uniprotkb:KIAA0250(gene name synonym)|uniprotkb:C1orf16(gene name synonym)|uniprotkb:EST1C(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6921131|imex:IM-21082-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167532.1|refseq:NP_775179.1|refseq:NP_963862.1|refseq:NP_963863.2|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q92540|rcsb pdb:1YA0|reactome:R-HSA-975957|ensembl:ENSG00000116698(gene)|ensembl:ENST00000347615(transcript)|ensembl:ENSP00000340766|ensembl:ENST00000507469|ensembl:ENSP00000425133|ensembl:ENST00000508461|ensembl:ENSP00000426915|ensembl:ENST00000515829|ensembl:ENSP00000421358 refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N - - - figure legend:Figure 6A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/06 2015/06/25 rogid:HgJSiXiQQT33P4AyLMd2pmFB/VM9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:1AC4B9A70B7F9172|rigid:0Az6RGO4p6pqDIw1cj7d1XPQXH8 false necessary binding region:54-54|necessary binding region:141-141|necessary binding region:142-142|v5 tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UPR3 uniprotkb:Q92540 intact:EBI-3400861|ensembl:ENSP00000355261|uniprotkb:Q5QJE7|uniprotkb:Q659C7|uniprotkb:Q8IXC0|uniprotkb:Q8IY09|uniprotkb:Q96IJ7|uniprotkb:D3DVB7 intact:EBI-719830|uniprotkb:Q5T1Q0|uniprotkb:Q6PIE0|uniprotkb:Q7Z7H9|uniprotkb:Q8IXC1|uniprotkb:Q8IXC2|intact:EBI-28984519|ensembl:ENSP00000340766|uniprotkb:B4DRB2|uniprotkb:E9PCI0|uniprotkb:E9PEH2 psi-mi:smg5_human(display_long)|uniprotkb:SMG5(gene name)|psi-mi:SMG5(display_short)|uniprotkb:EST1B(gene name synonym)|uniprotkb:KIAA1089(gene name synonym)|uniprotkb:EST1-like protein B(gene name synonym)|uniprotkb:LPTS-RP1(gene name synonym)|uniprotkb:LPTS-interacting protein(gene name synonym)|uniprotkb:SMG-5 homolog(gene name synonym) psi-mi:smg7_human(display_long)|uniprotkb:SMG-7 homolog(gene name synonym)|uniprotkb:EST1-like protein C(gene name synonym)|uniprotkb:SMG7(gene name)|psi-mi:SMG7(display_short)|uniprotkb:KIAA0250(gene name synonym)|uniprotkb:C1orf16(gene name synonym)|uniprotkb:EST1C(gene name synonym) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-10894454|imex:IM-21082-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198952(gene)|ensembl:ENST00000361813(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q9UPR3|rcsb pdb:2HWY|reactome:R-HSA-975957|interpro:IPR002716(PilT protein, N-terminal)|refseq:NP_056142.2 refseq:NP_001167532.1|refseq:NP_775179.1|refseq:NP_963862.1|refseq:NP_963863.2|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q92540|rcsb pdb:1YA0|reactome:R-HSA-975957|ensembl:ENSG00000116698(gene)|ensembl:ENST00000347615(transcript)|ensembl:ENSP00000340766|ensembl:ENST00000507469|ensembl:ENSP00000425133|ensembl:ENST00000508461|ensembl:ENSP00000426915|ensembl:ENST00000515829|ensembl:ENSP00000421358 - - - figure legend:Figure 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/06 2015/06/25 rogid:HeKpTzaiwDkA7b7lvjiODr7yuxA9606 rogid:HgJSiXiQQT33P4AyLMd2pmFB/VM9606 rigid:RPX9EMgRuV7hEgJo+IOYEsOnTN8 false v5 tag:c-c|sbp:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UPR3 uniprotkb:Q92900 intact:EBI-3400861|ensembl:ENSP00000355261|uniprotkb:Q5QJE7|uniprotkb:Q659C7|uniprotkb:Q8IXC0|uniprotkb:Q8IY09|uniprotkb:Q96IJ7|uniprotkb:D3DVB7 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:smg5_human(display_long)|uniprotkb:SMG5(gene name)|psi-mi:SMG5(display_short)|uniprotkb:EST1B(gene name synonym)|uniprotkb:KIAA1089(gene name synonym)|uniprotkb:EST1-like protein B(gene name synonym)|uniprotkb:LPTS-RP1(gene name synonym)|uniprotkb:LPTS-interacting protein(gene name synonym)|uniprotkb:SMG-5 homolog(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-10894454|imex:IM-21082-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198952(gene)|ensembl:ENST00000361813(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q9UPR3|rcsb pdb:2HWY|reactome:R-HSA-975957|interpro:IPR002716(PilT protein, N-terminal)|refseq:NP_056142.2 refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N - - - figure legend:Figure 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/06 2015/06/25 rogid:HeKpTzaiwDkA7b7lvjiODr7yuxA9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 rigid:RPX9EMgRuV7hEgJo+IOYEsOnTN8 false v5 tag:c-c|sbp:?-? ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:G5ECF1 uniprotkb:G5EF47 intact:EBI-6919737|ensemblmetazoa:W02D3.8.1 intact:EBI-6919756|ensemblmetazoa:Y73B6A.4.1 psi-mi:g5ecf1_caeel(display_long)|uniprotkb:smg-5(gene name)|psi-mi:smg-5(display_short)|uniprotkb:CELE_W02D3.8(orf name)|uniprotkb:W02D3.8(orf name) psi-mi:g5ef47_caeel(display_long)|uniprotkb:smg-7(gene name)|psi-mi:smg-7(display_short)|uniprotkb:CELE_Y73B6A.4(orf name)|uniprotkb:Y73B6A.4(orf name) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6919754|wwpdb:3zhe|imex:IM-21082-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016246"(RNA interference)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030538"(embryonic genitalia morphogenesis)|go:"GO:0034660"(ncRNA metabolic process)|go:"GO:0051721"(protein phosphatase 2A binding)|ensemblmetazoa:WBGene00004883(gene)|ensemblmetazoa:W02D3.8.1(transcript)|refseq:NP_491929.1|rcsb pdb:3ZHE|wormbase:W02D3.8|interpro:IPR002716(PilT protein, N-terminal) ensemblmetazoa:WBGene00004885(gene)|ensemblmetazoa:Y73B6A.4.1(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070034"(telomerase RNA binding)|refseq:NP_501033.1|interpro:IPR018834|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:3ZHE|wormbase:Y73B6A.4 - - - 3d-resolution:3A|3d-r-factors:Rworking 0.222 Rfree 0.249|figure legend:Fig. 3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2013/08/06 2015/06/25 rogid:sNbOuUztL2DZdEtpruQdkcMjV946239 rogid:qF+MjAHXTZxmT7fwSGfPiufV26s6239 intact-crc:8C59EEB5B1CF02AB|rigid:WH3n6E5O/wwPZCElZmtuY0rDhY4 false glutathione s tranferase tag:n-n|mutation decreasing interaction strength:91-91 maltose binding protein tag:?-?|mutation decreasing interaction strength:80-80 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q92900 uniprotkb:Q9UPR3 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 intact:EBI-3400861|ensembl:ENSP00000355261|uniprotkb:Q5QJE7|uniprotkb:Q659C7|uniprotkb:Q8IXC0|uniprotkb:Q8IY09|uniprotkb:Q96IJ7|uniprotkb:D3DVB7 psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:smg5_human(display_long)|uniprotkb:SMG5(gene name)|psi-mi:SMG5(display_short)|uniprotkb:EST1B(gene name synonym)|uniprotkb:KIAA1089(gene name synonym)|uniprotkb:EST1-like protein B(gene name synonym)|uniprotkb:LPTS-RP1(gene name synonym)|uniprotkb:LPTS-interacting protein(gene name synonym)|uniprotkb:SMG-5 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6932245|imex:IM-21082-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N ensembl:ENSG00000198952(gene)|ensembl:ENST00000361813(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q9UPR3|rcsb pdb:2HWY|reactome:R-HSA-975957|interpro:IPR002716(PilT protein, N-terminal)|refseq:NP_056142.2 - - - figure legend:Figure 6D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/06 2015/06/25 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 rogid:HeKpTzaiwDkA7b7lvjiODr7yuxA9606 intact-crc:BBC095356D8526B4|rigid:RPX9EMgRuV7hEgJo+IOYEsOnTN8 false v5 tag:?-?|sbp:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92900 uniprotkb:Q92540 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 intact:EBI-719830|uniprotkb:Q5T1Q0|uniprotkb:Q6PIE0|uniprotkb:Q7Z7H9|uniprotkb:Q8IXC1|uniprotkb:Q8IXC2|intact:EBI-28984519|ensembl:ENSP00000340766|uniprotkb:B4DRB2|uniprotkb:E9PCI0|uniprotkb:E9PEH2 psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:smg7_human(display_long)|uniprotkb:SMG-7 homolog(gene name synonym)|uniprotkb:EST1-like protein C(gene name synonym)|uniprotkb:SMG7(gene name)|psi-mi:SMG7(display_short)|uniprotkb:KIAA0250(gene name synonym)|uniprotkb:C1orf16(gene name synonym)|uniprotkb:EST1C(gene name synonym) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6932245|imex:IM-21082-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N refseq:NP_001167532.1|refseq:NP_775179.1|refseq:NP_963862.1|refseq:NP_963863.2|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q92540|rcsb pdb:1YA0|reactome:R-HSA-975957|ensembl:ENSG00000116698(gene)|ensembl:ENST00000347615(transcript)|ensembl:ENSP00000340766|ensembl:ENST00000507469|ensembl:ENSP00000425133|ensembl:ENST00000508461|ensembl:ENSP00000426915|ensembl:ENST00000515829|ensembl:ENSP00000421358 - - - figure legend:Figure 6D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/06 2015/06/25 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 rogid:HgJSiXiQQT33P4AyLMd2pmFB/VM9606 intact-crc:BBC095356D8526B4|rigid:RPX9EMgRuV7hEgJo+IOYEsOnTN8 false v5 tag:?-?|sbp:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92540 uniprotkb:Q9UPR3 intact:EBI-719830|uniprotkb:Q5T1Q0|uniprotkb:Q6PIE0|uniprotkb:Q7Z7H9|uniprotkb:Q8IXC1|uniprotkb:Q8IXC2|intact:EBI-28984519|ensembl:ENSP00000340766|uniprotkb:B4DRB2|uniprotkb:E9PCI0|uniprotkb:E9PEH2 intact:EBI-3400861|ensembl:ENSP00000355261|uniprotkb:Q5QJE7|uniprotkb:Q659C7|uniprotkb:Q8IXC0|uniprotkb:Q8IY09|uniprotkb:Q96IJ7|uniprotkb:D3DVB7 psi-mi:smg7_human(display_long)|uniprotkb:SMG-7 homolog(gene name synonym)|uniprotkb:EST1-like protein C(gene name synonym)|uniprotkb:SMG7(gene name)|psi-mi:SMG7(display_short)|uniprotkb:KIAA0250(gene name synonym)|uniprotkb:C1orf16(gene name synonym)|uniprotkb:EST1C(gene name synonym) psi-mi:smg5_human(display_long)|uniprotkb:SMG5(gene name)|psi-mi:SMG5(display_short)|uniprotkb:EST1B(gene name synonym)|uniprotkb:KIAA1089(gene name synonym)|uniprotkb:EST1-like protein B(gene name synonym)|uniprotkb:LPTS-RP1(gene name synonym)|uniprotkb:LPTS-interacting protein(gene name synonym)|uniprotkb:SMG-5 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6921318|imex:IM-21082-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167532.1|refseq:NP_775179.1|refseq:NP_963862.1|refseq:NP_963863.2|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q92540|rcsb pdb:1YA0|reactome:R-HSA-975957|ensembl:ENSG00000116698(gene)|ensembl:ENST00000347615(transcript)|ensembl:ENSP00000340766|ensembl:ENST00000507469|ensembl:ENSP00000425133|ensembl:ENST00000508461|ensembl:ENSP00000426915|ensembl:ENST00000515829|ensembl:ENSP00000421358 ensembl:ENSG00000198952(gene)|ensembl:ENST00000361813(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q9UPR3|rcsb pdb:2HWY|reactome:R-HSA-975957|interpro:IPR002716(PilT protein, N-terminal)|refseq:NP_056142.2 - - - figure legend:Figure 6C.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/06 2015/06/25 rogid:HgJSiXiQQT33P4AyLMd2pmFB/VM9606 rogid:HeKpTzaiwDkA7b7lvjiODr7yuxA9606 intact-crc:D0210A21EF42EE13|rigid:RPX9EMgRuV7hEgJo+IOYEsOnTN8 false v5 tag:n-n|sbp:?-?|mutation:163-163|mutation:66-66 ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92540 uniprotkb:Q92900 intact:EBI-719830|uniprotkb:Q5T1Q0|uniprotkb:Q6PIE0|uniprotkb:Q7Z7H9|uniprotkb:Q8IXC1|uniprotkb:Q8IXC2|intact:EBI-28984519|ensembl:ENSP00000340766|uniprotkb:B4DRB2|uniprotkb:E9PCI0|uniprotkb:E9PEH2 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:smg7_human(display_long)|uniprotkb:SMG-7 homolog(gene name synonym)|uniprotkb:EST1-like protein C(gene name synonym)|uniprotkb:SMG7(gene name)|psi-mi:SMG7(display_short)|uniprotkb:KIAA0250(gene name synonym)|uniprotkb:C1orf16(gene name synonym)|uniprotkb:EST1C(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6921318|imex:IM-21082-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001167532.1|refseq:NP_775179.1|refseq:NP_963862.1|refseq:NP_963863.2|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q92540|rcsb pdb:1YA0|reactome:R-HSA-975957|ensembl:ENSG00000116698(gene)|ensembl:ENST00000347615(transcript)|ensembl:ENSP00000340766|ensembl:ENST00000507469|ensembl:ENSP00000425133|ensembl:ENST00000508461|ensembl:ENSP00000426915|ensembl:ENST00000515829|ensembl:ENSP00000421358 refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N - - - figure legend:Figure 6C.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/06 2015/06/25 rogid:HgJSiXiQQT33P4AyLMd2pmFB/VM9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:D0210A21EF42EE13|rigid:RPX9EMgRuV7hEgJo+IOYEsOnTN8 false v5 tag:n-n|sbp:?-?|mutation:163-163|mutation:66-66 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UPR3 uniprotkb:Q92540 intact:EBI-3400861|ensembl:ENSP00000355261|uniprotkb:Q5QJE7|uniprotkb:Q659C7|uniprotkb:Q8IXC0|uniprotkb:Q8IY09|uniprotkb:Q96IJ7|uniprotkb:D3DVB7 intact:EBI-719830|uniprotkb:Q5T1Q0|uniprotkb:Q6PIE0|uniprotkb:Q7Z7H9|uniprotkb:Q8IXC1|uniprotkb:Q8IXC2|intact:EBI-28984519|ensembl:ENSP00000340766|uniprotkb:B4DRB2|uniprotkb:E9PCI0|uniprotkb:E9PEH2 psi-mi:smg5_human(display_long)|uniprotkb:SMG5(gene name)|psi-mi:SMG5(display_short)|uniprotkb:EST1B(gene name synonym)|uniprotkb:KIAA1089(gene name synonym)|uniprotkb:EST1-like protein B(gene name synonym)|uniprotkb:LPTS-RP1(gene name synonym)|uniprotkb:LPTS-interacting protein(gene name synonym)|uniprotkb:SMG-5 homolog(gene name synonym) psi-mi:smg7_human(display_long)|uniprotkb:SMG-7 homolog(gene name synonym)|uniprotkb:EST1-like protein C(gene name synonym)|uniprotkb:SMG7(gene name)|psi-mi:SMG7(display_short)|uniprotkb:KIAA0250(gene name synonym)|uniprotkb:C1orf16(gene name synonym)|uniprotkb:EST1C(gene name synonym) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6921015|imex:IM-21082-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198952(gene)|ensembl:ENST00000361813(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q9UPR3|rcsb pdb:2HWY|reactome:R-HSA-975957|interpro:IPR002716(PilT protein, N-terminal)|refseq:NP_056142.2 refseq:NP_001167532.1|refseq:NP_775179.1|refseq:NP_963862.1|refseq:NP_963863.2|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q92540|rcsb pdb:1YA0|reactome:R-HSA-975957|ensembl:ENSG00000116698(gene)|ensembl:ENST00000347615(transcript)|ensembl:ENSP00000340766|ensembl:ENST00000507469|ensembl:ENSP00000425133|ensembl:ENST00000508461|ensembl:ENSP00000426915|ensembl:ENST00000515829|ensembl:ENSP00000421358 - - - figure legend:Figure 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/06 2015/06/25 rogid:HeKpTzaiwDkA7b7lvjiODr7yuxA9606 rogid:HgJSiXiQQT33P4AyLMd2pmFB/VM9606 intact-crc:63EED601930CF87D|rigid:RPX9EMgRuV7hEgJo+IOYEsOnTN8 false v5 tag:c-c|sbp:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UPR3 uniprotkb:Q92900 intact:EBI-3400861|ensembl:ENSP00000355261|uniprotkb:Q5QJE7|uniprotkb:Q659C7|uniprotkb:Q8IXC0|uniprotkb:Q8IY09|uniprotkb:Q96IJ7|uniprotkb:D3DVB7 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:smg5_human(display_long)|uniprotkb:SMG5(gene name)|psi-mi:SMG5(display_short)|uniprotkb:EST1B(gene name synonym)|uniprotkb:KIAA1089(gene name synonym)|uniprotkb:EST1-like protein B(gene name synonym)|uniprotkb:LPTS-RP1(gene name synonym)|uniprotkb:LPTS-interacting protein(gene name synonym)|uniprotkb:SMG-5 homolog(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6921015|imex:IM-21082-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198952(gene)|ensembl:ENST00000361813(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|mint:Q9UPR3|rcsb pdb:2HWY|reactome:R-HSA-975957|interpro:IPR002716(PilT protein, N-terminal)|refseq:NP_056142.2 refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N - - - figure legend:Figure 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/08/06 2015/06/25 rogid:HeKpTzaiwDkA7b7lvjiODr7yuxA9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:63EED601930CF87D|rigid:RPX9EMgRuV7hEgJo+IOYEsOnTN8 false v5 tag:c-c|sbp:?-? N-phosphorylated residue:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:G5ECF1 uniprotkb:G5EF47 intact:EBI-6919737|ensemblmetazoa:W02D3.8.1 intact:EBI-6919756|ensemblmetazoa:Y73B6A.4.1 psi-mi:g5ecf1_caeel(display_long)|uniprotkb:smg-5(gene name)|psi-mi:smg-5(display_short)|uniprotkb:CELE_W02D3.8(orf name)|uniprotkb:W02D3.8(orf name) psi-mi:g5ef47_caeel(display_long)|uniprotkb:smg-7(gene name)|psi-mi:smg-7(display_short)|uniprotkb:CELE_Y73B6A.4(orf name)|uniprotkb:Y73B6A.4(orf name) psi-mi:"MI:0114"(x-ray crystallography) Jonas et al. (2013) pubmed:23348841|imex:IM-21082 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-10894691|imex:IM-21082-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011990(Tetratricopeptide-like helical)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016246"(RNA interference)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030538"(embryonic genitalia morphogenesis)|go:"GO:0034660"(ncRNA metabolic process)|go:"GO:0051721"(protein phosphatase 2A binding)|ensemblmetazoa:WBGene00004883(gene)|ensemblmetazoa:W02D3.8.1(transcript)|refseq:NP_491929.1|rcsb pdb:3ZHE|wormbase:W02D3.8|interpro:IPR002716(PilT protein, N-terminal) ensemblmetazoa:WBGene00004885(gene)|ensemblmetazoa:Y73B6A.4.1(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0070034"(telomerase RNA binding)|refseq:NP_501033.1|interpro:IPR018834|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:3ZHE|wormbase:Y73B6A.4 - - - 3d-resolution:3A|3d-r-factors:Rworking 0.222 Rfree 0.249|figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/08/06 2015/06/26 rogid:sNbOuUztL2DZdEtpruQdkcMjV946239 rogid:qF+MjAHXTZxmT7fwSGfPiufV26s6239 rigid:WH3n6E5O/wwPZCElZmtuY0rDhY4 false glutathione s tranferase tag:n-n his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)