#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q61337	uniprotkb:Q64373-1	intact:EBI-400328|ensembl:ENSMUSP00000025910	intact:EBI-526380|ensembl:ENSMUSP00000007803|ensembl:ENSMUSP00000105445	psi-mi:bad_mouse(display_long)|uniprotkb:Bad(gene name)|psi-mi:Bad(display_short)|uniprotkb:Bbc6(gene name synonym)|uniprotkb:Bcl-2-binding component 6(gene name synonym)|uniprotkb:Bcl-xL/Bcl-2-associated death promoter(gene name synonym)|uniprotkb:Bcl2 antagonist of cell death(gene name synonym)	psi-mi:q64373-1(display_long)|uniprotkb:Bcl2l1(gene name)|psi-mi:Bcl2l1(display_short)|uniprotkb:Bcl2l(gene name synonym)|uniprotkb:Bclx(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:Bcl-xL(isoform synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Yan et al. (2013)	pubmed:23332762|imex:IM-20848	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6693214|imex:IM-20848-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031548.1|ensembl:ENSMUSG00000024959(gene)|ensembl:ENSMUST00000025910(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:1902220"(positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1904710"(positive regulation of granulosa cell apoptotic process)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR018868|rcsb pdb:2BZW|reactome:R-MMU-111447|reactome:R-MMU-111453|reactome:R-MMU-193648|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033574"(response to testosterone)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046031"(ADP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0071247"(cellular response to chromate)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901423"(response to benzene)|dip:DIP-273N	intact:EBI-526361(bclx_mouse)|ensembl:ENSMUSG00000007659(gene)|ensembl:ENSMUST00000007803(transcript)|ensembl:ENSMUST00000109820(transcript)	go:"GO:0005739"(mitochondrion)	-	-	figure legend:Fig 5C, 5E|comment:Only nonphosphorylated, but not Ser26-phosphorylated, BAD was found to associate with BCL-XL|agonist:TNF-alpha|comment:Interaction observed in Ikbkb -/- cells.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts)	-	2013/05/29	2014/10/16	rogid:s7+c8lnBrmxed496XKF41JljqRk10090	rogid:Rh+X0lr/BxZl4GwIm2D/vtGTbkY10090	intact-crc:40EAB2FFBE1D1A85|rigid:yfxfjMovzI5T1U8u8s5Sm25Cszg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q64373-1	uniprotkb:Q61337	intact:EBI-526380|ensembl:ENSMUSP00000007803|ensembl:ENSMUSP00000105445	intact:EBI-400328|ensembl:ENSMUSP00000025910	psi-mi:q64373-1(display_long)|uniprotkb:Bcl2l1(gene name)|psi-mi:Bcl2l1(display_short)|uniprotkb:Bcl2l(gene name synonym)|uniprotkb:Bclx(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:Bcl-xL(isoform synonym)	psi-mi:bad_mouse(display_long)|uniprotkb:Bad(gene name)|psi-mi:Bad(display_short)|uniprotkb:Bbc6(gene name synonym)|uniprotkb:Bcl-2-binding component 6(gene name synonym)|uniprotkb:Bcl-xL/Bcl-2-associated death promoter(gene name synonym)|uniprotkb:Bcl2 antagonist of cell death(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Yan et al. (2013)	pubmed:23332762|imex:IM-20848	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6693227|imex:IM-20848-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-526361(bclx_mouse)|ensembl:ENSMUSG00000007659(gene)|ensembl:ENSMUST00000007803(transcript)|ensembl:ENSMUST00000109820(transcript)	refseq:NP_031548.1|ensembl:ENSMUSG00000024959(gene)|ensembl:ENSMUST00000025910(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:1902220"(positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1904710"(positive regulation of granulosa cell apoptotic process)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR018868|rcsb pdb:2BZW|reactome:R-MMU-111447|reactome:R-MMU-111453|reactome:R-MMU-193648|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0033574"(response to testosterone)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046031"(ADP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060139"(positive regulation of apoptotic process by virus)|go:"GO:0071247"(cellular response to chromate)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901423"(response to benzene)|dip:DIP-273N	go:"GO:0005739"(mitochondrion)	-	-	figure legend:Supp. Fig. 4B|comment:Only nonphosphorylated, but not Ser26-phosphorylated, BAD was found to associate with BCL-XL. 14-3-3 proteins were also present in this interaction.|comment:Interaction observed in Ikbkb -/- cells.|agonist:TNF-alpha|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts)	-	2013/05/29	2014/10/16	rogid:Rh+X0lr/BxZl4GwIm2D/vtGTbkY10090	rogid:s7+c8lnBrmxed496XKF41JljqRk10090	intact-crc:2D73F91D974124E3|rigid:yfxfjMovzI5T1U8u8s5Sm25Cszg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)