#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P63141	uniprotkb:O55242	intact:EBI-644033|uniprotkb:P15386|uniprotkb:Q02010|uniprotkb:Q8C8W4|uniprotkb:B2RS05|ensembl:ENSMUSP00000041702|ensembl:ENSMUSP00000142873|ensembl:ENSMUSP00000143798	intact:EBI-1557700|uniprotkb:Q9JKU9|ensembl:ENSMUSP00000056027	psi-mi:kcna2_mouse(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv1.2(gene name synonym)|uniprotkb:Kcna2(gene name)|psi-mi:Kcna2(display_short)|uniprotkb:MK2(gene name synonym)	psi-mi:sgmr1_mouse(display_long)|uniprotkb:Sigma 1-type opioid receptor(gene name synonym)|uniprotkb:Sigmar1(gene name)|psi-mi:Sigmar1(display_short)|uniprotkb:Oprs1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Kourrich et al. (2013)	imex:IM-20846|pubmed:23332758	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6692884|imex:IM-20846-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032443.3|ensembl:ENSMUSG00000040724(gene)|ensembl:ENSMUST00000038695(transcript)|ensembl:ENSMUST00000196403(transcript)|ensembl:ENSMUST00000197470(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019894"(kinesin binding)|go:"GO:0021633"(optic nerve structural organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033010"(paranodal junction)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044305"(calyx of Held)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR004049(Potassium channel, voltage dependent, Kv1.2)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:5WIE|reactome:R-MMU-1296072|refseq:XP_006501113.1|refseq:XP_006501114.1|refseq:XP_006501111.1|refseq:XP_006501112.1|refseq:XP_006501115.1|refseq:XP_006501116.1|refseq:XP_006501117.1|refseq:XP_006501118.1|dip:DIP-32239N	refseq:NP_035144.1|refseq:NP_001273480.1|refseq:NP_001273467.1|refseq:NP_001273468.1|refseq:NP_001273469.1|refseq:NP_001273470.1|refseq:XP_017175516.1|ensembl:ENSMUSG00000036078(gene)|ensembl:ENSMUST00000059354(transcript)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006869"(lipid transport)|go:"GO:0007399"(nervous system development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036474"(cell death in response to hydrogen peroxide)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR006716(ERG2 and sigma1 receptor-like)	go:"GO:0005886"(plasma membrane)	-	-	figure legend:Fig. 7A|agonist:Cocaine|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-ng108_15)|taxid:10090(Mouse NG108-15)	-	2013/05/17	2014/10/16	rogid:AimFojHr+yjzzdtmfxUCRBTvJyc10090	rogid:KEY6+88EzI03FH6CSiBPcKYF3Ps10090	intact-crc:F0DE847342851A66|rigid:RsXJdNJW1ba4kgzTHBpyzmU8sog	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P63141	uniprotkb:O55242	intact:EBI-644033|uniprotkb:P15386|uniprotkb:Q02010|uniprotkb:Q8C8W4|uniprotkb:B2RS05|ensembl:ENSMUSP00000041702|ensembl:ENSMUSP00000142873|ensembl:ENSMUSP00000143798	intact:EBI-1557700|uniprotkb:Q9JKU9|ensembl:ENSMUSP00000056027	psi-mi:kcna2_mouse(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv1.2(gene name synonym)|uniprotkb:Kcna2(gene name)|psi-mi:Kcna2(display_short)|uniprotkb:MK2(gene name synonym)	psi-mi:sgmr1_mouse(display_long)|uniprotkb:Sigma 1-type opioid receptor(gene name synonym)|uniprotkb:Sigmar1(gene name)|psi-mi:Sigmar1(display_short)|uniprotkb:Oprs1(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Kourrich et al. (2013)	imex:IM-20846|pubmed:23332758	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6692749|imex:IM-20846-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032443.3|ensembl:ENSMUSG00000040724(gene)|ensembl:ENSMUST00000038695(transcript)|ensembl:ENSMUST00000196403(transcript)|ensembl:ENSMUST00000197470(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019894"(kinesin binding)|go:"GO:0021633"(optic nerve structural organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033010"(paranodal junction)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044305"(calyx of Held)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR004049(Potassium channel, voltage dependent, Kv1.2)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:5WIE|reactome:R-MMU-1296072|refseq:XP_006501113.1|refseq:XP_006501114.1|refseq:XP_006501111.1|refseq:XP_006501112.1|refseq:XP_006501115.1|refseq:XP_006501116.1|refseq:XP_006501117.1|refseq:XP_006501118.1|dip:DIP-32239N	refseq:NP_035144.1|refseq:NP_001273480.1|refseq:NP_001273467.1|refseq:NP_001273468.1|refseq:NP_001273469.1|refseq:NP_001273470.1|refseq:XP_017175516.1|ensembl:ENSMUSG00000036078(gene)|ensembl:ENSMUST00000059354(transcript)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006869"(lipid transport)|go:"GO:0007399"(nervous system development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036474"(cell death in response to hydrogen peroxide)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR006716(ERG2 and sigma1 receptor-like)	-	-	-	figure legend:Supp. Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2013/05/17	2014/10/16	rogid:AimFojHr+yjzzdtmfxUCRBTvJyc10090	rogid:KEY6+88EzI03FH6CSiBPcKYF3Ps10090	intact-crc:80F27A9D84B9DC3B|rigid:RsXJdNJW1ba4kgzTHBpyzmU8sog	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O55242	uniprotkb:P63141	intact:EBI-1557700|uniprotkb:Q9JKU9|ensembl:ENSMUSP00000056027	intact:EBI-644033|uniprotkb:P15386|uniprotkb:Q02010|uniprotkb:Q8C8W4|uniprotkb:B2RS05|ensembl:ENSMUSP00000041702|ensembl:ENSMUSP00000142873|ensembl:ENSMUSP00000143798	psi-mi:sgmr1_mouse(display_long)|uniprotkb:Sigma 1-type opioid receptor(gene name synonym)|uniprotkb:Sigmar1(gene name)|psi-mi:Sigmar1(display_short)|uniprotkb:Oprs1(gene name synonym)	psi-mi:kcna2_mouse(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv1.2(gene name synonym)|uniprotkb:Kcna2(gene name)|psi-mi:Kcna2(display_short)|uniprotkb:MK2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kourrich et al. (2013)	imex:IM-20846|pubmed:23332758	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6676054|imex:IM-20846-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035144.1|refseq:NP_001273480.1|refseq:NP_001273467.1|refseq:NP_001273468.1|refseq:NP_001273469.1|refseq:NP_001273470.1|refseq:XP_017175516.1|ensembl:ENSMUSG00000036078(gene)|ensembl:ENSMUST00000059354(transcript)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006869"(lipid transport)|go:"GO:0007399"(nervous system development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036474"(cell death in response to hydrogen peroxide)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR006716(ERG2 and sigma1 receptor-like)	refseq:NP_032443.3|ensembl:ENSMUSG00000040724(gene)|ensembl:ENSMUST00000038695(transcript)|ensembl:ENSMUST00000196403(transcript)|ensembl:ENSMUST00000197470(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019894"(kinesin binding)|go:"GO:0021633"(optic nerve structural organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033010"(paranodal junction)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044305"(calyx of Held)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR004049(Potassium channel, voltage dependent, Kv1.2)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:5WIE|reactome:R-MMU-1296072|refseq:XP_006501113.1|refseq:XP_006501114.1|refseq:XP_006501111.1|refseq:XP_006501112.1|refseq:XP_006501115.1|refseq:XP_006501116.1|refseq:XP_006501117.1|refseq:XP_006501118.1|dip:DIP-32239N	-	-	-	figure legend:Fig. 5, Supp. Fig. 5B, 5C|agonist:Cocaine|antagonist:BD1063 -a Sig-1R antagonist.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain)	-	2013/05/17	2014/10/16	rogid:KEY6+88EzI03FH6CSiBPcKYF3Ps10090	rogid:AimFojHr+yjzzdtmfxUCRBTvJyc10090	intact-crc:ECCFA1A34022CA01|rigid:RsXJdNJW1ba4kgzTHBpyzmU8sog	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9R0C9	uniprotkb:P63141	intact:EBI-1557826|uniprotkb:Q9R1J7|uniprotkb:Q9Z2W2|ensembl:ENSRNOP00000019795	intact:EBI-644033|uniprotkb:P15386|uniprotkb:Q02010|uniprotkb:Q8C8W4|uniprotkb:B2RS05|ensembl:ENSMUSP00000041702|ensembl:ENSMUSP00000142873|ensembl:ENSMUSP00000143798	psi-mi:sgmr1_rat(display_long)|uniprotkb:Sigma 1-type opioid receptor(gene name synonym)|uniprotkb:Sigmar1(gene name)|psi-mi:Sigmar1(display_short)|uniprotkb:Oprs1(gene name synonym)	psi-mi:kcna2_mouse(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv1.2(gene name synonym)|uniprotkb:Kcna2(gene name)|psi-mi:Kcna2(display_short)|uniprotkb:MK2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kourrich et al. (2013)	imex:IM-20846|pubmed:23332758	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6692782|imex:IM-20846-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:68364|refseq:NP_112258.1|ensembl:ENSRNOG00000014604(gene)|ensembl:ENSRNOT00000019795(transcript)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006869"(lipid transport)|go:"GO:0007399"(nervous system development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036474"(cell death in response to hydrogen peroxide)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR006716(ERG2 and sigma1 receptor-like)	refseq:NP_032443.3|ensembl:ENSMUSG00000040724(gene)|ensembl:ENSMUST00000038695(transcript)|ensembl:ENSMUST00000196403(transcript)|ensembl:ENSMUST00000197470(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019894"(kinesin binding)|go:"GO:0021633"(optic nerve structural organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033010"(paranodal junction)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044305"(calyx of Held)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR004049(Potassium channel, voltage dependent, Kv1.2)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:5WIE|reactome:R-MMU-1296072|refseq:XP_006501113.1|refseq:XP_006501114.1|refseq:XP_006501111.1|refseq:XP_006501112.1|refseq:XP_006501115.1|refseq:XP_006501116.1|refseq:XP_006501117.1|refseq:XP_006501118.1|dip:DIP-32239N	-	-	-	figure legend:Fig. 6, Supp Fig. 6Aa,6Ba|agonist:Cocaine|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-ng108_15)|taxid:10090(Mouse NG108-15)	-	2013/05/17	2014/10/16	rogid:vmBRHHmEmLai9FHo38yHlnwvEyY10116	rogid:AimFojHr+yjzzdtmfxUCRBTvJyc10090	intact-crc:5BDE2E7CDC1A5BEE|rigid:D92Oqr6zYcgfm2QyrOEGzXtvz3o	false	his tag:?-?|v5 tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9R0C9	uniprotkb:P63141	intact:EBI-1557826|uniprotkb:Q9R1J7|uniprotkb:Q9Z2W2|ensembl:ENSRNOP00000019795	intact:EBI-644033|uniprotkb:P15386|uniprotkb:Q02010|uniprotkb:Q8C8W4|uniprotkb:B2RS05|ensembl:ENSMUSP00000041702|ensembl:ENSMUSP00000142873|ensembl:ENSMUSP00000143798	psi-mi:sgmr1_rat(display_long)|uniprotkb:Sigma 1-type opioid receptor(gene name synonym)|uniprotkb:Sigmar1(gene name)|psi-mi:Sigmar1(display_short)|uniprotkb:Oprs1(gene name synonym)	psi-mi:kcna2_mouse(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv1.2(gene name synonym)|uniprotkb:Kcna2(gene name)|psi-mi:Kcna2(display_short)|uniprotkb:MK2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kourrich et al. (2013)	imex:IM-20846|pubmed:23332758	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6859672|imex:IM-20846-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:68364|refseq:NP_112258.1|ensembl:ENSRNOG00000014604(gene)|ensembl:ENSRNOT00000019795(transcript)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006869"(lipid transport)|go:"GO:0007399"(nervous system development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036474"(cell death in response to hydrogen peroxide)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR006716(ERG2 and sigma1 receptor-like)	refseq:NP_032443.3|ensembl:ENSMUSG00000040724(gene)|ensembl:ENSMUST00000038695(transcript)|ensembl:ENSMUST00000196403(transcript)|ensembl:ENSMUST00000197470(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019894"(kinesin binding)|go:"GO:0021633"(optic nerve structural organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033010"(paranodal junction)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044305"(calyx of Held)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR004049(Potassium channel, voltage dependent, Kv1.2)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:5WIE|reactome:R-MMU-1296072|refseq:XP_006501113.1|refseq:XP_006501114.1|refseq:XP_006501111.1|refseq:XP_006501112.1|refseq:XP_006501115.1|refseq:XP_006501116.1|refseq:XP_006501117.1|refseq:XP_006501118.1|dip:DIP-32239N	-	-	-	figure legend:Supp 6Bb|agonist:Cocaine|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-neuro_2_a)|taxid:10090("Mus musculus albino neuroblastoma cell line neuro 2 a (N2a)")	-	2013/05/17	2014/10/16	rogid:vmBRHHmEmLai9FHo38yHlnwvEyY10116	rogid:AimFojHr+yjzzdtmfxUCRBTvJyc10090	intact-crc:BFB0AE56ACC62D93|rigid:D92Oqr6zYcgfm2QyrOEGzXtvz3o	false	his tag:?-?|v5 tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P63141	uniprotkb:Q9R0C9	intact:EBI-644033|uniprotkb:P15386|uniprotkb:Q02010|uniprotkb:Q8C8W4|uniprotkb:B2RS05|ensembl:ENSMUSP00000041702|ensembl:ENSMUSP00000142873|ensembl:ENSMUSP00000143798	intact:EBI-1557826|uniprotkb:Q9R1J7|uniprotkb:Q9Z2W2|ensembl:ENSRNOP00000019795	psi-mi:kcna2_mouse(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv1.2(gene name synonym)|uniprotkb:Kcna2(gene name)|psi-mi:Kcna2(display_short)|uniprotkb:MK2(gene name synonym)	psi-mi:sgmr1_rat(display_long)|uniprotkb:Sigma 1-type opioid receptor(gene name synonym)|uniprotkb:Sigmar1(gene name)|psi-mi:Sigmar1(display_short)|uniprotkb:Oprs1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kourrich et al. (2013)	imex:IM-20846|pubmed:23332758	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6692762|imex:IM-20846-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032443.3|ensembl:ENSMUSG00000040724(gene)|ensembl:ENSMUST00000038695(transcript)|ensembl:ENSMUST00000196403(transcript)|ensembl:ENSMUST00000197470(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019894"(kinesin binding)|go:"GO:0021633"(optic nerve structural organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033010"(paranodal junction)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044305"(calyx of Held)|go:"GO:0045188"(regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR004049(Potassium channel, voltage dependent, Kv1.2)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|rcsb pdb:5WIE|reactome:R-MMU-1296072|refseq:XP_006501113.1|refseq:XP_006501114.1|refseq:XP_006501111.1|refseq:XP_006501112.1|refseq:XP_006501115.1|refseq:XP_006501116.1|refseq:XP_006501117.1|refseq:XP_006501118.1|dip:DIP-32239N	rgd:68364|refseq:NP_112258.1|ensembl:ENSRNOG00000014604(gene)|ensembl:ENSRNOT00000019795(transcript)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006869"(lipid transport)|go:"GO:0007399"(nervous system development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036474"(cell death in response to hydrogen peroxide)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR006716(ERG2 and sigma1 receptor-like)	-	-	-	figure legend:Supp Fig. 6Ab|agonist:Cocaine|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-ng108_15)|taxid:10090(Mouse NG108-15)	-	2013/05/17	2014/10/16	rogid:AimFojHr+yjzzdtmfxUCRBTvJyc10090	rogid:vmBRHHmEmLai9FHo38yHlnwvEyY10116	intact-crc:EC13E21DCF21C8ED|rigid:D92Oqr6zYcgfm2QyrOEGzXtvz3o	false	-	v5 tag:?-?|his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)