#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:G5EG62 uniprotkb:Q18688 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:"MI:0114"(x-ray crystallography) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675188|imex:IM-20787-1|wwpdb:4i2z - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282 - - - figure legend:Supp. Table 1|3d-resolution:2.9A|3d-r-factors:Rworking = 0.24 Rfree = 0.26|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 intact-crc:BB9DA74556B0BECB|rigid:S06Dy9Jw4/j4kjuX8XvNzGgFroM false his tag:c-c sufficient binding region:693-702 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EG62 uniprotkb:P09446 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-322448|uniprotkb:Q93601|ensemblmetazoa:F26D10.3.1|ensemblmetazoa:F26D10.3.2 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:hsp1_caeel(display_long)|uniprotkb:hsp-1(gene name)|psi-mi:hsp-1(display_short)|uniprotkb:hsp70a(gene name synonym)|uniprotkb:F26D10.3(orf name)|uniprotkb:Heat shock 70 kDa protein A(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675284|imex:IM-20787-2|wwpdb:4i2w - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM refseq:NP_503068.1|wormbase:F26D10.3|reactome:R-CEL-3371453|ensemblmetazoa:F26D10.3.1(transcript)|ensemblmetazoa:F26D10.3.2(transcript)|ensemblmetazoa:WBGene00002005(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:2P32|rcsb pdb:4I2W|reactome:R-CEL-72163|reactome:R-CEL-6798695|reactome:R-CEL-3371571|reactome:R-CEL-8856828|dip:DIP-26882N|reactome:R-CEL-3371497|reactome:R-CEL-888590 - - - figure legend:Supp. Table 1|3d-resolution:3.6A|3d-r-factors:Rworking = 0.23 Rfree = 0.28|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:9ydEtLk204NKqMg4mSg+Oit/t0I6239 intact-crc:4E108B4540590521|rigid:JvfP1UlcSd+nRg7Vo1ArB8Zu4c8 false his tag:c-c sufficient binding region:631-640 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09446 uniprotkb:G5EG62 intact:EBI-322448|uniprotkb:Q93601|ensemblmetazoa:F26D10.3.1|ensemblmetazoa:F26D10.3.2 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 psi-mi:hsp1_caeel(display_long)|uniprotkb:hsp-1(gene name)|psi-mi:hsp-1(display_short)|uniprotkb:hsp70a(gene name synonym)|uniprotkb:F26D10.3(orf name)|uniprotkb:Heat shock 70 kDa protein A(gene name synonym) psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:"MI:0071"(molecular sieving) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675358|imex:IM-20787-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_503068.1|wormbase:F26D10.3|reactome:R-CEL-3371453|ensemblmetazoa:F26D10.3.1(transcript)|ensemblmetazoa:F26D10.3.2(transcript)|ensemblmetazoa:WBGene00002005(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:2P32|rcsb pdb:4I2W|reactome:R-CEL-72163|reactome:R-CEL-6798695|reactome:R-CEL-3371571|reactome:R-CEL-8856828|dip:DIP-26882N|reactome:R-CEL-3371497|reactome:R-CEL-888590 ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM - - - figure legend:Fig. 2B, Supp. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/17 2014/10/16 rogid:9ydEtLk204NKqMg4mSg+Oit/t0I6239 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 intact-crc:185FE4A33FE4AA9A|rigid:JvfP1UlcSd+nRg7Vo1ArB8Zu4c8 false necessary binding region:636-640|his tag:n-n his tag:c-c - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q18688 uniprotkb:G5EG62 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:"MI:0071"(molecular sieving) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675349|imex:IM-20787-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282 ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM - - - figure legend:Fig. 2B, Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/17 2014/10/16 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 intact-crc:F365AFCF3014D1E2|rigid:S06Dy9Jw4/j4kjuX8XvNzGgFroM false his tag:n-n|necessary binding region:698-702 his tag:c-c - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:G5EG62 uniprotkb:G5EG62 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:"MI:0030"(cross-linking study) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675412|imex:IM-20787-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM - - - figure legend:Fig. 5A, Supp. Fig. 5A|comment:Chain formation depends strongly on UNC-45 concentration, with the longer chains occurring only at elevated protein concentration.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 intact-crc:6076C60738A585FD|rigid:sObReGIUieCOXFBqG+yIkO3+iLg false his tag:c-c|mutation:452-452|mutation:480-480,484-484|mutation:121-121 his tag:c-c|mutation:452-452|mutation:480-480,484-484|mutation:121-121 2 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:G5EG62 uniprotkb:G5EG62 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:"MI:0030"(cross-linking study) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675420|imex:IM-20787-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM - - - figure legend:Fig. 5A, Supp Fig. 5A|comment:Chain formation depends strongly on UNC-45 concentration, with the longer chains occurring only at elevated protein concentration.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 intact-crc:7A88CD5A4B70CBA4|rigid:sObReGIUieCOXFBqG+yIkO3+iLg false mutation:452-452|his tag:c-c mutation:452-452|his tag:c-c 3 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:G5EG62 uniprotkb:G5EG62 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:"MI:0030"(cross-linking study) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675428|imex:IM-20787-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM - - - figure legend:Fig. 5A, Supp. Fig. 5A|comment:Chain formation depends strongly on UNC-45 concentration, with the longer chains occurring only at elevated protein concentration.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 intact-crc:162742BCEA4C1F89|rigid:sObReGIUieCOXFBqG+yIkO3+iLg false his tag:c-c|mutation:452-452 his tag:c-c|mutation:452-452 4 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:G5EG62 uniprotkb:G5EG62 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:"MI:0030"(cross-linking study) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675472|imex:IM-20787-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM - - - figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 intact-crc:C52BCCB0CB52EC52|rigid:sObReGIUieCOXFBqG+yIkO3+iLg false his tag:c-c|mutation:452-452 his tag:c-c|mutation:452-452 5 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:G5EG62 uniprotkb:G5EG62 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:"MI:0030"(cross-linking study) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675456|imex:IM-20787-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM - - - figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 intact-crc:C52AD6ED8C48B114|rigid:sObReGIUieCOXFBqG+yIkO3+iLg false his tag:c-c|mutation:452-452 his tag:c-c|mutation:452-452 3 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:G5EG62 uniprotkb:G5EG62 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:"MI:0030"(cross-linking study) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675454|imex:IM-20787-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM - - - figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 intact-crc:C52BB7AAAA29F633|rigid:sObReGIUieCOXFBqG+yIkO3+iLg false his tag:c-c|mutation:452-452 his tag:c-c|mutation:452-452 4 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:G5EG62 uniprotkb:G5EG62 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:"MI:0030"(cross-linking study) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675452|imex:IM-20787-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM - - - figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 intact-crc:8C51AD69786BF517|rigid:sObReGIUieCOXFBqG+yIkO3+iLg false his tag:c-c|mutation:452-452 his tag:c-c|mutation:452-452 2 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:G5EG62 uniprotkb:G5EG62 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:"MI:0030"(cross-linking study) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675490|imex:IM-20787-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM - - - figure legend:Fig. 5c|comment:UV-activated pBpa452 crosslinks to the Lys131/Ile132/Lys133 sequence|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 intact-crc:D85F3ECEFF615AE4|rigid:sObReGIUieCOXFBqG+yIkO3+iLg false his tag:c-c|mutation:452-452 his tag:c-c|mutation:452-452 - 0 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:G5EG62 uniprotkb:Q18688 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:"MI:0065"(isothermal titration calorimetry) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675330|imex:IM-20787-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282 - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.1x10^-5(molar) 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 intact-crc:F202C3AFB8292AA3|rigid:S06Dy9Jw4/j4kjuX8XvNzGgFroM false his tag:c-c his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5EG62 uniprotkb:P09446 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-322448|uniprotkb:Q93601|ensemblmetazoa:F26D10.3.1|ensemblmetazoa:F26D10.3.2 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:hsp1_caeel(display_long)|uniprotkb:hsp-1(gene name)|psi-mi:hsp-1(display_short)|uniprotkb:hsp70a(gene name synonym)|uniprotkb:F26D10.3(orf name)|uniprotkb:Heat shock 70 kDa protein A(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675312|imex:IM-20787-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM refseq:NP_503068.1|wormbase:F26D10.3|reactome:R-CEL-3371453|ensemblmetazoa:F26D10.3.1(transcript)|ensemblmetazoa:F26D10.3.2(transcript)|ensemblmetazoa:WBGene00002005(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:2P32|rcsb pdb:4I2W|reactome:R-CEL-72163|reactome:R-CEL-6798695|reactome:R-CEL-3371571|reactome:R-CEL-8856828|dip:DIP-26882N|reactome:R-CEL-3371497|reactome:R-CEL-888590 - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.2x10^-4(molar) 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:9ydEtLk204NKqMg4mSg+Oit/t0I6239 intact-crc:ACF057AF6400F88A|rigid:JvfP1UlcSd+nRg7Vo1ArB8Zu4c8 false his tag:c-c|mutation disrupting interaction strength:82-82 sufficient binding region:631-640 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q18688 uniprotkb:G5EG62 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:"MI:0065"(isothermal titration calorimetry) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6675307|imex:IM-20787-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282 ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.4x10^-5(molar) 2013/05/17 2014/10/16 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 intact-crc:99AD6C743BA4E4E2|rigid:S06Dy9Jw4/j4kjuX8XvNzGgFroM false sufficient binding region:693-702 his tag:c-c|mutation disrupting interaction strength:82-82 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02566 uniprotkb:G5EG62 intact:EBI-329238|uniprotkb:O02244|ensemblmetazoa:F11C3.3.1|ensemblmetazoa:F11C3.3.2|ensemblmetazoa:F11C3.3.3 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 psi-mi:myo4_caeel(display_long)|uniprotkb:unc-54(gene name)|psi-mi:unc-54(display_short)|uniprotkb:myo-4(gene name synonym)|uniprotkb:Myosin heavy chain B(gene name synonym)|uniprotkb:Uncoordinated protein 54(gene name synonym)|uniprotkb:F11C3.3(orf name) psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6675496|imex:IM-20787-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493596.1|wormbase:F11C3.3|dip:DIP-26548N|ensemblmetazoa:F11C3.3.1(transcript)|ensemblmetazoa:F11C3.3.2(transcript)|ensemblmetazoa:F11C3.3.3(transcript)|ensemblmetazoa:WBGene00006789(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0018991"(oviposition)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031672"(A band)|go:"GO:0051015"(actin filament binding)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|rcsb pdb:6QDJ|go:"GO:0040011"(locomotion) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM - - - figure legend:Supp. Fig. 6D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2013/05/17 2014/10/16 rogid:3b8NY0RNiYO8jJI3dfdNoVXa69c6239 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 intact-crc:7E893421325A95F0|rigid:RCiD2ElqfxVYgGQ9rkWU/jqWAvI false - mutation decreasing interaction strength:480-480,484-484|flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:G5EG62 uniprotkb:P02566 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-329238|uniprotkb:O02244|ensemblmetazoa:F11C3.3.1|ensemblmetazoa:F11C3.3.2|ensemblmetazoa:F11C3.3.3 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:myo4_caeel(display_long)|uniprotkb:unc-54(gene name)|psi-mi:unc-54(display_short)|uniprotkb:myo-4(gene name synonym)|uniprotkb:Myosin heavy chain B(gene name synonym)|uniprotkb:Uncoordinated protein 54(gene name synonym)|uniprotkb:F11C3.3(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6675384|imex:IM-20787-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM refseq:NP_493596.1|wormbase:F11C3.3|dip:DIP-26548N|ensemblmetazoa:F11C3.3.1(transcript)|ensemblmetazoa:F11C3.3.2(transcript)|ensemblmetazoa:F11C3.3.3(transcript)|ensemblmetazoa:WBGene00006789(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0018991"(oviposition)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031672"(A band)|go:"GO:0051015"(actin filament binding)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|rcsb pdb:6QDJ|go:"GO:0040011"(locomotion) - - - figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:3b8NY0RNiYO8jJI3dfdNoVXa69c6239 intact-crc:C28BC2E8E2720D4F|rigid:S6UFcnvjVAwsSYnf3Q+GBZkVudM false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:G5EG62 uniprotkb:Q18688 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6675384|imex:IM-20787-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282 - - - figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 intact-crc:C28BC2E8E2720D4F|rigid:S6UFcnvjVAwsSYnf3Q+GBZkVudM false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:G5EG62 uniprotkb:P02566 intact:EBI-6675165|ensemblmetazoa:F30H5.1.1 intact:EBI-329238|uniprotkb:O02244|ensemblmetazoa:F11C3.3.1|ensemblmetazoa:F11C3.3.2|ensemblmetazoa:F11C3.3.3 psi-mi:g5eg62_caeel(display_long)|uniprotkb:unc-45(gene name)|psi-mi:unc-45(display_short)|uniprotkb:CELE_F30H5.1(orf name)|uniprotkb:F30H5.1(orf name) psi-mi:myo4_caeel(display_long)|uniprotkb:unc-54(gene name)|psi-mi:unc-54(display_short)|uniprotkb:myo-4(gene name synonym)|uniprotkb:Myosin heavy chain B(gene name synonym)|uniprotkb:Uncoordinated protein 54(gene name synonym)|uniprotkb:F11C3.3(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gazda et al. (2013) pubmed:23332754|imex:IM-20787 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6675393|imex:IM-20787-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F30H5.1.1(transcript)|ensemblmetazoa:WBGene00006781(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR019734|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR024660|refseq:NP_497205.1|rcsb pdb:4I2W|rcsb pdb:4I2Z|wormbase:F30H5.1|rcsb pdb:5MZU|rcsb pdb:6QDK|rcsb pdb:6QDL|rcsb pdb:6QDM refseq:NP_493596.1|wormbase:F11C3.3|dip:DIP-26548N|ensemblmetazoa:F11C3.3.1(transcript)|ensemblmetazoa:F11C3.3.2(transcript)|ensemblmetazoa:F11C3.3.3(transcript)|ensemblmetazoa:WBGene00006789(gene)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0018991"(oviposition)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031672"(A band)|go:"GO:0051015"(actin filament binding)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|rcsb pdb:6QDJ|go:"GO:0040011"(locomotion) - - - figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) - 2013/05/17 2014/10/16 rogid:NhJ+U8cdOnnRydF1kNMUf7GOi606239 rogid:3b8NY0RNiYO8jJI3dfdNoVXa69c6239 intact-crc:13AD028A582E2259|rigid:RCiD2ElqfxVYgGQ9rkWU/jqWAvI false necessary binding region:602-630|flag tag:c-c|mutation:758-758 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)