#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P06701 uniprotkb:P06701 intact:EBI-17230|uniprotkb:D6VZ77|uniprotkb:E9P924|ensemblfungi:YLR442C intact:EBI-17230|uniprotkb:D6VZ77|uniprotkb:E9P924|ensemblfungi:YLR442C psi-mi:sir3_yeast(display_long)|uniprotkb:SIR3(gene name)|psi-mi:SIR3(display_short)|uniprotkb:CMT1(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:STE8(gene name synonym)|uniprotkb:L9753.10(orf name)|uniprotkb:YLR442C(locus name)|uniprotkb:Silent information regulator 3(gene name synonym) psi-mi:sir3_yeast(display_long)|uniprotkb:SIR3(gene name)|psi-mi:SIR3(display_short)|uniprotkb:CMT1(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:STE8(gene name synonym)|uniprotkb:L9753.10(orf name)|uniprotkb:YLR442C(locus name)|uniprotkb:Silent information regulator 3(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Oppikofer et al. (2013) pubmed:23299941|imex:IM-22178 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8872619|imex:IM-22178-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013547.3|sgd:S000004434|ensemblfungi:YLR442C(gene)|ensemblfungi:YLR442C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:2FL7|rcsb pdb:2FVU|rcsb pdb:3OWT|rcsb pdb:3TE6|rcsb pdb:3TU4|rcsb pdb:3ZCO|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4KUL|rcsb pdb:4LD9|rcsb pdb:4KUI|dip:DIP-595N|mint:P06701 refseq:NP_013547.3|sgd:S000004434|ensemblfungi:YLR442C(gene)|ensemblfungi:YLR442C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:2FL7|rcsb pdb:2FVU|rcsb pdb:3OWT|rcsb pdb:3TE6|rcsb pdb:3TU4|rcsb pdb:3ZCO|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4KUL|rcsb pdb:4LD9|rcsb pdb:4KUI|dip:DIP-595N|mint:P06701 rcsb pdb:3ZCO crc64:CA2503D7645397AC crc64:CA2503D7645397AC figure legend:F1F T1 F3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/11/22 2014/10/16 rogid:M+pLXY5ZyBMA0tQaEIwTkK6U2SE559292 rogid:M+pLXY5ZyBMA0tQaEIwTkK6U2SE559292 intact-crc:8E72AF876ED3B45D|rigid:IEk+jD8IiPGwq7BEJ5NKcAkPTxM false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06701 uniprotkb:P06701 intact:EBI-17230|uniprotkb:D6VZ77|uniprotkb:E9P924|ensemblfungi:YLR442C intact:EBI-17230|uniprotkb:D6VZ77|uniprotkb:E9P924|ensemblfungi:YLR442C psi-mi:sir3_yeast(display_long)|uniprotkb:SIR3(gene name)|psi-mi:SIR3(display_short)|uniprotkb:CMT1(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:STE8(gene name synonym)|uniprotkb:L9753.10(orf name)|uniprotkb:YLR442C(locus name)|uniprotkb:Silent information regulator 3(gene name synonym) psi-mi:sir3_yeast(display_long)|uniprotkb:SIR3(gene name)|psi-mi:SIR3(display_short)|uniprotkb:CMT1(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:STE8(gene name synonym)|uniprotkb:L9753.10(orf name)|uniprotkb:YLR442C(locus name)|uniprotkb:Silent information regulator 3(gene name synonym) psi-mi:"MI:0096"(pull down) Oppikofer et al. (2013) pubmed:23299941|imex:IM-22178 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8872632|imex:IM-22178-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013547.3|sgd:S000004434|ensemblfungi:YLR442C(gene)|ensemblfungi:YLR442C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:2FL7|rcsb pdb:2FVU|rcsb pdb:3OWT|rcsb pdb:3TE6|rcsb pdb:3TU4|rcsb pdb:3ZCO|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4KUL|rcsb pdb:4LD9|rcsb pdb:4KUI|dip:DIP-595N|mint:P06701 refseq:NP_013547.3|sgd:S000004434|ensemblfungi:YLR442C(gene)|ensemblfungi:YLR442C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:2FL7|rcsb pdb:2FVU|rcsb pdb:3OWT|rcsb pdb:3TE6|rcsb pdb:3TU4|rcsb pdb:3ZCO|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4KUL|rcsb pdb:4LD9|rcsb pdb:4KUI|dip:DIP-595N|mint:P06701 - crc64:CA2503D7645397AC crc64:CA2503D7645397AC figure legend:f1g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7111(trini-high_5)|taxid:7111(Trichoplusia ni cell line from eggs) - 2013/11/22 2014/10/16 rogid:M+pLXY5ZyBMA0tQaEIwTkK6U2SE559292 rogid:M+pLXY5ZyBMA0tQaEIwTkK6U2SE559292 intact-crc:3E1BDE0B0E071AD7|rigid:OPrvSW2dZV0stZd4RQ1R8BIzDLg false his tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P06701 uniprotkb:P06701 intact:EBI-17230|uniprotkb:D6VZ77|uniprotkb:E9P924|ensemblfungi:YLR442C intact:EBI-17230|uniprotkb:D6VZ77|uniprotkb:E9P924|ensemblfungi:YLR442C psi-mi:sir3_yeast(display_long)|uniprotkb:SIR3(gene name)|psi-mi:SIR3(display_short)|uniprotkb:CMT1(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:STE8(gene name synonym)|uniprotkb:L9753.10(orf name)|uniprotkb:YLR442C(locus name)|uniprotkb:Silent information regulator 3(gene name synonym) psi-mi:sir3_yeast(display_long)|uniprotkb:SIR3(gene name)|psi-mi:SIR3(display_short)|uniprotkb:CMT1(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:STE8(gene name synonym)|uniprotkb:L9753.10(orf name)|uniprotkb:YLR442C(locus name)|uniprotkb:Silent information regulator 3(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Oppikofer et al. (2013) pubmed:23299941|imex:IM-22178 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8872654|imex:IM-22178-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013547.3|sgd:S000004434|ensemblfungi:YLR442C(gene)|ensemblfungi:YLR442C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:2FL7|rcsb pdb:2FVU|rcsb pdb:3OWT|rcsb pdb:3TE6|rcsb pdb:3TU4|rcsb pdb:3ZCO|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4KUL|rcsb pdb:4LD9|rcsb pdb:4KUI|dip:DIP-595N|mint:P06701 refseq:NP_013547.3|sgd:S000004434|ensemblfungi:YLR442C(gene)|ensemblfungi:YLR442C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:2FL7|rcsb pdb:2FVU|rcsb pdb:3OWT|rcsb pdb:3TE6|rcsb pdb:3TU4|rcsb pdb:3ZCO|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4KUL|rcsb pdb:4LD9|rcsb pdb:4KUI|dip:DIP-595N|mint:P06701 - crc64:CA2503D7645397AC crc64:CA2503D7645397AC figure legend:sf2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/11/22 2014/10/16 rogid:M+pLXY5ZyBMA0tQaEIwTkK6U2SE559292 rogid:M+pLXY5ZyBMA0tQaEIwTkK6U2SE559292 intact-crc:EEB1B452FF3D7D25|rigid:IEk+jD8IiPGwq7BEJ5NKcAkPTxM false mutation disrupting interaction:909-909,861-861 mutation disrupting interaction:909-909,861-861 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06701 uniprotkb:P06701 intact:EBI-17230|uniprotkb:D6VZ77|uniprotkb:E9P924|ensemblfungi:YLR442C intact:EBI-17230|uniprotkb:D6VZ77|uniprotkb:E9P924|ensemblfungi:YLR442C psi-mi:sir3_yeast(display_long)|uniprotkb:SIR3(gene name)|psi-mi:SIR3(display_short)|uniprotkb:CMT1(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:STE8(gene name synonym)|uniprotkb:L9753.10(orf name)|uniprotkb:YLR442C(locus name)|uniprotkb:Silent information regulator 3(gene name synonym) psi-mi:sir3_yeast(display_long)|uniprotkb:SIR3(gene name)|psi-mi:SIR3(display_short)|uniprotkb:CMT1(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:STE8(gene name synonym)|uniprotkb:L9753.10(orf name)|uniprotkb:YLR442C(locus name)|uniprotkb:Silent information regulator 3(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Oppikofer et al. (2013) pubmed:23299941|imex:IM-22178 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8872647|imex:IM-22178-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013547.3|sgd:S000004434|ensemblfungi:YLR442C(gene)|ensemblfungi:YLR442C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:2FL7|rcsb pdb:2FVU|rcsb pdb:3OWT|rcsb pdb:3TE6|rcsb pdb:3TU4|rcsb pdb:3ZCO|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4KUL|rcsb pdb:4LD9|rcsb pdb:4KUI|dip:DIP-595N|mint:P06701 refseq:NP_013547.3|sgd:S000004434|ensemblfungi:YLR442C(gene)|ensemblfungi:YLR442C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:2FL7|rcsb pdb:2FVU|rcsb pdb:3OWT|rcsb pdb:3TE6|rcsb pdb:3TU4|rcsb pdb:3ZCO|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4KUL|rcsb pdb:4LD9|rcsb pdb:4KUI|dip:DIP-595N|mint:P06701 - crc64:CA2503D7645397AC crc64:CA2503D7645397AC figure legend:sf2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/11/22 2014/10/16 rogid:M+pLXY5ZyBMA0tQaEIwTkK6U2SE559292 rogid:M+pLXY5ZyBMA0tQaEIwTkK6U2SE559292 intact-crc:513167B224025775|rigid:IEk+jD8IiPGwq7BEJ5NKcAkPTxM false binding-associated region:845-978 binding-associated region:845-978 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06701 uniprotkb:P06701 intact:EBI-17230|uniprotkb:D6VZ77|uniprotkb:E9P924|ensemblfungi:YLR442C intact:EBI-17230|uniprotkb:D6VZ77|uniprotkb:E9P924|ensemblfungi:YLR442C psi-mi:sir3_yeast(display_long)|uniprotkb:SIR3(gene name)|psi-mi:SIR3(display_short)|uniprotkb:CMT1(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:STE8(gene name synonym)|uniprotkb:L9753.10(orf name)|uniprotkb:YLR442C(locus name)|uniprotkb:Silent information regulator 3(gene name synonym) psi-mi:sir3_yeast(display_long)|uniprotkb:SIR3(gene name)|psi-mi:SIR3(display_short)|uniprotkb:CMT1(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:STE8(gene name synonym)|uniprotkb:L9753.10(orf name)|uniprotkb:YLR442C(locus name)|uniprotkb:Silent information regulator 3(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Oppikofer et al. (2013) pubmed:23299941|imex:IM-22178 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-9120182|imex:IM-22178-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013547.3|sgd:S000004434|ensemblfungi:YLR442C(gene)|ensemblfungi:YLR442C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:2FL7|rcsb pdb:2FVU|rcsb pdb:3OWT|rcsb pdb:3TE6|rcsb pdb:3TU4|rcsb pdb:3ZCO|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4KUL|rcsb pdb:4LD9|rcsb pdb:4KUI|dip:DIP-595N|mint:P06701 refseq:NP_013547.3|sgd:S000004434|ensemblfungi:YLR442C(gene)|ensemblfungi:YLR442C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:2FL7|rcsb pdb:2FVU|rcsb pdb:3OWT|rcsb pdb:3TE6|rcsb pdb:3TU4|rcsb pdb:3ZCO|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4KUL|rcsb pdb:4LD9|rcsb pdb:4KUI|dip:DIP-595N|mint:P06701 - crc64:CA2503D7645397AC crc64:CA2503D7645397AC figure legend:sf1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/11/22 2014/10/16 rogid:M+pLXY5ZyBMA0tQaEIwTkK6U2SE559292 rogid:M+pLXY5ZyBMA0tQaEIwTkK6U2SE559292 intact-crc:C84BF5E65B83BA38|rigid:IEk+jD8IiPGwq7BEJ5NKcAkPTxM false binding-associated region:845-978 binding-associated region:845-978 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)