#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6P542 uniprotkb:Q9D2E2 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-3870537|uniprotkb:Q3UFD8|uniprotkb:Q8R5A4|uniprotkb:Q9D412|ensembl:ENSMUSP00000030451 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:toe1_mouse(display_long)|uniprotkb:Toe1(gene name)|psi-mi:Toe1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_080930.1|ensembl:ENSMUSG00000028688(gene)|ensembl:ENSMUST00000030451(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:eITTx6ktPKOrfHi20Sf0OdGolzs10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q921K2 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6261012|ensembl:ENSMUSP00000027777 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:q921k2_mouse(display_long)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUST00000027777(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:Q921K2|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|ensembl:ENSMUSG00000026496(gene)|refseq:NP_031441.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:LeuW0EFJDL/7bR1fRoDZvwA2g/A10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q8BIQ5 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910260|ensembl:ENSMUSP00000033609|uniprotkb:A2AEJ9|uniprotkb:A2AEK0|uniprotkb:Q8K1Y6|uniprotkb:Q9ERC2 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:cstf2_mouse(display_long)|uniprotkb:Cstf2(gene name)|psi-mi:Cstf2(display_short)|uniprotkb:CF-1 64 kDa subunit(gene name synonym)|uniprotkb:Cleavage stimulation factor 64 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_001277328.1|ensembl:ENSMUSG00000031256(gene)|ensembl:ENSMUST00000033609(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016604"(nuclear body)|go:"GO:0071920"(cleavage body)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR025742|interpro:IPR026896|interpro:IPR033105|interpro:IPR035979|interpro:IPR038192|mint:Q8BIQ5|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-77595|refseq:NP_573459.1 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:34MgxXRI1XsU5aMjgMnm93voyx810090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P14869 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-529949|uniprotkb:Q99L54|ensembl:ENSMUSP00000083705 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:rla0_mouse(display_long)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Rplp0(gene name)|psi-mi:Rplp0(display_short)|uniprotkb:Arbp(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_031501.1|ensembl:ENSMUSG00000067274(gene)|ensembl:ENSMUST00000086519(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042277"(peptide binding)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P14869|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:WHl41TZwjtqRSeIExT3vyjrZsJs10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q80ZH7 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6907970|ensembl:ENSMUSP00000090525|ensembl:ENSMUSP00000133805 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:q80zh7_mouse(display_long)|uniprotkb:Lig3(gene name)|psi-mi:Lig3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_001278174.1|refseq:NP_001278175.1|refseq:NP_001278176.1|ensembl:ENSMUSG00000020697(gene)|ensembl:ENSMUST00000092849(transcript)|ensembl:ENSMUST00000173722(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR031916|interpro:IPR036420|interpro:IPR036599|interpro:IPR036957|refseq:XP_006532413.1|refseq:NP_034846.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:NKBRjF9UuMVOyezvfD1ajVjce3M10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P34022 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910236|ensembl:ENSMUSP00000111309|uniprotkb:P34023|uniprotkb:Q3TL81|uniprotkb:Q9D894|uniprotkb:Q9DCA3 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:rang_mouse(display_long)|uniprotkb:Ranbp1(gene name)|psi-mi:Ranbp1(display_short)|uniprotkb:Htf9-a(gene name synonym)|uniprotkb:Htf9a(gene name synonym)|uniprotkb:HpaII tiny fragments locus 9a protein(gene name synonym)|uniprotkb:Ran-binding protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000005732(gene)|ensembl:ENSMUST00000115645(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0032838"(plasma membrane bounded cell projection cytoplasm)|go:"GO:0035690"|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0046907"(intracellular transport)|go:"GO:0051592"(response to calcium ion)|go:"GO:0072750"(cellular response to leptomycin B)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|mint:P34022|refseq:NP_035369.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:9WwwCo8F99dZTxcULB2smcoaqFE10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q8BX17 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-2550292|uniprotkb:Q3UPH2|ensembl:ENSMUSP00000036603 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:gemi5_mouse(display_long)|uniprotkb:Gemin5(gene name)|psi-mi:Gemin5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000037275(gene)|ensembl:ENSMUST00000035604(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0016604"(nuclear body)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0032797"(SMN complex)|go:"GO:0034718"(SMN-Gemin2 complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|reactome:R-MMU-191859|refseq:NP_001160141.1|refseq:NP_001160142.1|refseq:NP_001160143.1|refseq:NP_766146.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:a2dQ9yhjRVYev2Iml4Zgj8PQi6s10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q8BG79 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910301|ensembl:ENSMUSP00000027027|uniprotkb:Q3TIS8|uniprotkb:Q3UX04|uniprotkb:Q80XN7|uniprotkb:Q8BZV5|uniprotkb:Q8C0F8 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:c19l2_mouse(display_long)|uniprotkb:Cwf19l2(gene name)|psi-mi:Cwf19l2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000025898(gene)|ensembl:ENSMUST00000027027(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR006767(Protein similar to CwfJ, C-terminal 2)|interpro:IPR006768(Protein similar to CwfJ, C-terminal 1)|interpro:IPR036265|interpro:IPR040194|mint:Q8BG79|refseq:NP_081821.1 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:JQ9Z9xuFNVwa6He9KRdiAJAE3RA10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q3UHD6 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910393|ensembl:ENSMUSP00000102904|uniprotkb:Q7TQL6|uniprotkb:Q80TZ1|uniprotkb:Q9CYB5 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:snx27_mouse(display_long)|uniprotkb:Snx27(gene name)|psi-mi:Snx27(display_short)|uniprotkb:Kiaa0488(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 go:"GO:0006886"(intracellular protein transport)|go:"GO:0007165"(signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016197"(endosomal transport)|go:"GO:0030904"(retromer complex)|ensembl:ENSMUSG00000028136(gene)|ensembl:ENSMUST00000107283(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0071203"(WASH complex)|go:"GO:0005768"(endosome)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|interpro:IPR000159(Ras-association)|interpro:IPR001478(PDZ/DHR/GLGF)|go:"GO:0005769"(early endosome)|interpro:IPR001683(Phox-like)|interpro:IPR028667|interpro:IPR029071|go:"GO:0005829"(cytosol)|interpro:IPR036034|go:"GO:0005886"(plasma membrane)|interpro:IPR036871|interpro:IPR037827|interpro:IPR037831|interpro:IPR037833|interpro:IPR037835|mint:Q3UHD6|refseq:NP_001075953.1|refseq:NP_083997.1|dip:DIP-60337N - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:+pFe87lSKQPJuMDWsiMU4iXhGOw10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q3TZX8 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910341|ensembl:ENSMUSP00000081133|uniprotkb:A0PJC7|uniprotkb:B1AS65|uniprotkb:Q05A31|uniprotkb:Q8BQE1|uniprotkb:Q8C8L5|uniprotkb:Q8C9A8|uniprotkb:Q9D678 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:nol9_mouse(display_long)|uniprotkb:Nol9(gene name)|psi-mi:Nol9(display_short)|uniprotkb:Nucleolar protein 9(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000028948(gene)|ensembl:ENSMUST00000084116(transcript)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051731"(polynucleotide 5'-hydroxyl-kinase activity)|interpro:IPR027417|interpro:IPR032319|mint:Q3TZX8|reactome:R-MMU-6791226|refseq:NP_001153071.1|refseq:NP_083003.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:+ouzQxlnqezFE6OB+EPtscf8aMg10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q9EQU5 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-1543689|uniprotkb:Q9CY82|uniprotkb:Q9D0A9|uniprotkb:Q9Z181|uniprotkb:A2BE95|ensembl:ENSMUSP00000099930 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:set_mouse(display_long)|uniprotkb:Set(gene name)|psi-mi:Set(display_short)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_001191804.1|refseq:NP_076360.1|ensembl:ENSMUSG00000054766(gene)|ensembl:ENSMUST00000102866(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9EQU5|reactome:R-MMU-2299718|reactome:R-MMU-450520 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:1PEoqWcGzQ6q4T2SbfswpNI2Dr810090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q6P9Q4 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6909370|ensembl:ENSMUSP00000014922|uniprotkb:Q8BMK2 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:fhod1_mouse(display_long)|uniprotkb:Fhod1(gene name)|psi-mi:Fhod1(display_short)|uniprotkb:Fhos1(gene name synonym)|uniprotkb:Formin homolog overexpressed in spleen 1(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUST00000014922(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007097"(nuclear migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032059"(bleb)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0051660"(establishment of centrosome localization)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027647|interpro:IPR041387|interpro:IPR042201|mint:Q6P9Q4|ensembl:ENSMUSG00000014778(gene)|refseq:NP_808367.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:gzhlsIAZYIrpU+SOkY049Xby42c10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q9DCN2 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-4321444|ensembl:ENSMUSP00000018186 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:nb5r3_mouse(display_long)|uniprotkb:Cyb5r3(gene name)|psi-mi:Cyb5r3(display_short)|uniprotkb:Dia1(gene name synonym)|uniprotkb:Diaphorase-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_084063.1|refseq:XP_006520346.1|ensembl:ENSMUSG00000018042(gene)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016208"(AMP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|ensembl:ENSMUST00000018186(transcript)|go:"GO:0071949"(FAD binding)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|go:"GO:0051287"(NAD binding)|mint:Q9DCN2|reactome:R-MMU-196836|reactome:R-MMU-211945|reactome:R-MMU-6798695|dip:DIP-57517N - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:72QkmF4NeAFyp0tOl6Vxsol0Z6410090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:O35309 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910367|ensembl:ENSMUSP00000028314|ensembl:ENSMUSP00000108325|ensembl:ENSMUSP00000120647|uniprotkb:Q99M49 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:nmi_mouse(display_long)|uniprotkb:Nmi(gene name)|psi-mi:Nmi(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:XP_006498281.1|ensembl:ENSMUSG00000026946(gene)|ensembl:ENSMUST00000028314(transcript)|ensembl:ENSMUST00000112705(transcript)|ensembl:ENSMUST00000145481(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|refseq:NP_001135420.1|refseq:NP_001135421.1|refseq:NP_062274.1 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:9X5RUlhyAOGncBgay3QZBo+ga+w10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q3URQ0 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910284|ensembl:ENSMUSP00000030030|ensembl:ENSMUSP00000132498 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:tex10_mouse(display_long)|uniprotkb:Tex10(gene name)|psi-mi:Tex10(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:XP_006538018.1|refseq:XP_006538019.1|ensembl:ENSMUSG00000028345(gene)|ensembl:ENSMUST00000030030(transcript)|ensembl:ENSMUST00000164866(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0071339"(MLL1 complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024679|interpro:IPR037947|reactome:R-MMU-6791226|refseq:NP_758508.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:iGocOH1GUrHKJQ3umzAunS1LfLY10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q3UL36 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910384|ensembl:ENSMUSP00000039493|uniprotkb:Q80XJ0 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:argl1_mouse(display_long)|uniprotkb:Arglu1(gene name)|psi-mi:Arglu1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000040459(gene)|ensembl:ENSMUST00000048545(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR033371|refseq:NP_789819.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:43h52BC+BsS6BK7VRNDkfVsJNa410090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q9JLI8 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6908246|ensembl:ENSMUSP00000019118|uniprotkb:Q6ZQI2|uniprotkb:Q8BPK9|uniprotkb:Q8C3B7|uniprotkb:Q8CFU9 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:sart3_mouse(display_long)|uniprotkb:Sart3(gene name)|psi-mi:Sart3(display_short)|uniprotkb:Kiaa0156(gene name synonym)|uniprotkb:Tumor-rejection antigen SART3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000018974(gene)|ensembl:ENSMUST00000019118(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005691"(U6atac snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030624"(U6atac snRNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0061574"(ASAP complex)|go:"GO:0071001"(U4/U6 snRNP)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903586"(positive regulation of histone deubiquitination)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008669(Lsm interaction)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034217|interpro:IPR034218|interpro:IPR035979|refseq:NP_058622.1 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:8sHlrSQvdRLEdh54zyFG1fA4P8410090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q9D8C4 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6908025|ensembl:ENSMUSP00000010502|uniprotkb:Q3V2E7 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:in35_mouse(display_long)|uniprotkb:Ifi35(gene name)|psi-mi:Ifi35(display_short)|uniprotkb:Ifp35(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000010358(gene)|ensembl:ENSMUST00000010502(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034460|mint:Q9D8C4|refseq:NP_081596.1 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:690pLYDHOyQAO0FnFRfO6+La2UA10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q04690 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-397326|uniprotkb:Q61956|uniprotkb:Q61957|ensembl:ENSMUSP00000071289 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:nf1_mouse(display_long)|uniprotkb:Nf1(gene name)|psi-mi:Nf1(display_short)|uniprotkb:Neurofibromatosis-related protein NF-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_035027.1|refseq:XP_006532504.1|go:"GO:0007420"(brain development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0008542"(visual learning)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0021510"(spinal cord development)|go:"GO:0021764"(amygdala development)|go:"GO:0021897"(forebrain astrocyte development)|go:"GO:0021915"(neural tube development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0045685"(regulation of glial cell differentiation)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0050890"(cognition)|go:"GO:0061534"(gamma-aminobutyric acid secretion, neurotransmission)|go:"GO:0061535"(glutamate secretion, neurotransmission)|go:"GO:0098597"(observational learning)|go:"GO:0098793"(presynapse)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023152|interpro:IPR036865|interpro:IPR039360|mint:Q04690|go:"GO:0030424"(axon)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035021"(negative regulation of Rac protein signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043473"(pigmentation)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043535"(regulation of blood vessel endothelial cell migration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045545"(syndecan binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|ensembl:ENSMUSG00000020716(gene)|ensembl:ENSMUST00000071325(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001656"(metanephros development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001889"(liver development)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007154"(cell communication)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|reactome:R-MMU-5658442 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:aegHzgNy813/APoCjeM166e+MFE10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:A2BE28 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6909575|ensembl:ENSMUSP00000109495|uniprotkb:A2BE30|uniprotkb:Q6KAR5|uniprotkb:Q8C742 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:las1l_mouse(display_long)|uniprotkb:Las1l(gene name)|psi-mi:Las1l(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:XP_006528397.1|ensembl:ENSMUSG00000057421(gene)|ensembl:ENSMUST00000113864(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:A2BE28|reactome:R-MMU-6791226|refseq:NP_690035.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:Mhldr72nVCrOq1rjpRDqIcqNsg810090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P62918 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910319|ensembl:ENSMUSP00000004072|ensembl:ENSMUSP00000155657|uniprotkb:P25120|uniprotkb:Q3V288 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:rl8_mouse(display_long)|uniprotkb:Rpl8(gene name)|psi-mi:Rpl8(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62918|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000003970(gene)|ensembl:ENSMUST00000004072(transcript)|ensembl:ENSMUST00000229183(transcript)|go:"GO:0002181"(cytoplasmic translation)|refseq:NP_036183.1 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P14148 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-445010|uniprotkb:Q80UR0|ensembl:ENSMUSP00000071616 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:rl7_mouse(display_long)|uniprotkb:Rpl7(gene name)|psi-mi:Rpl7(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_035421.2|ensembl:ENSMUSG00000043716(gene)|ensembl:ENSMUST00000058437(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P14148|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:3mgKWwOhV0qZfTQwfsTkqol4iIY10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P47911 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-773947|uniprotkb:Q6P5I2|uniprotkb:Q925C3|ensembl:ENSMUSP00000031617 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:rl6_mouse(display_long)|uniprotkb:TAX-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Rpl6(gene name)|psi-mi:Rpl6(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_035420.2|refseq:XP_006530290.1|ensembl:ENSMUSG00000029614(gene)|ensembl:ENSMUST00000031617(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:P47911|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:rm/g3X/3zoauNoUW6K4M43n8e4810090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:O35381 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-643140|uniprotkb:P97437|ensembl:ENSMUSP00000082652 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:an32a_mouse(display_long)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Anp32a(gene name)|psi-mi:Anp32a(display_short)|uniprotkb:Anp32(gene name synonym)|uniprotkb:Lanp(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_033802.2|ensembl:ENSMUSG00000032249(gene)|ensembl:ENSMUST00000085519(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:O35381|rcsb pdb:2JQD|reactome:R-MMU-450520 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:flk6xO1N5PloQyQ9bOBHDzr3Hr010090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P06151 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-444940|ensembl:ENSMUSP00000036386|ensembl:ENSMUSP00000103267 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:ldha_mouse(display_long)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Ldha(gene name)|psi-mi:Ldha(display_short)|uniprotkb:Ldh-1(gene name synonym)|uniprotkb:Ldh1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_034829.1|ensembl:ENSMUSG00000063229(gene)|ensembl:ENSMUST00000005051(transcript)|ensembl:ENSMUST00000048209(transcript)|go:"GO:0004457"(lactate dehydrogenase activity)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0019244"(lactate biosynthetic process from pyruvate)|go:"GO:0019661"(glucose catabolic process to lactate via pyruvate)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042802"(identical protein binding)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P06151|reactome:R-MMU-70268 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:IErFuOIWq53/XyIxWgUyVi76VnM10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P15092 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910116|uniprotkb:Q921V9 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:ifi4_mouse(display_long)|uniprotkb:Ifi204(gene name)|psi-mi:Ifi204(display_short)|uniprotkb:Interferon-inducible protein p204(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001047"|go:"GO:0001078"|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0044822"|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0043032"(positive regulation of macrophage activation)|refseq:NP_032355.2|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|go:"GO:0005737"(cytoplasm)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0005730"(nucleolus)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0006351"(transcription, DNA-templated) - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:yK9xND/SFmZgIDZex/cWx58X3/g10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q99MD9 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-913410|uniprotkb:O35499|uniprotkb:O88993|uniprotkb:Q3V150|uniprotkb:Q99KE9 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:nasp_mouse(display_long)|uniprotkb:Nasp(gene name)|psi-mi:Nasp(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_001271158.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0015031"(protein transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0044877"(protein-containing complex binding)|refseq:NP_001074944.1|interpro:IPR019544|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q99MD9 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:kdLcXZo8FtCJsQJTD5bAIXInfsk10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P36371 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6909778|ensembl:ENSMUSP00000025197 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:tap2_mouse(display_long)|uniprotkb:Tap2(gene name)|psi-mi:Tap2(display_short)|uniprotkb:Abcb3(gene name synonym)|uniprotkb:Ham-2(gene name synonym)|uniprotkb:Ham2(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 3(gene name synonym)|uniprotkb:Histocompatibility antigen modifier 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000024339(gene)|ensembl:ENSMUST00000025197(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002481"(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:"GO:0002485"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:"GO:0002489"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent)|go:"GO:0002591"(positive regulation of antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0015433"(ABC-type peptide antigen transporter activity)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0015833"(peptide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042825"(TAP complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046967"(cytosol to endoplasmic reticulum transport)|go:"GO:0046968"(peptide antigen transport)|go:"GO:0046978"(TAP1 binding)|go:"GO:0046979"(TAP2 binding)|go:"GO:0046980"(tapasin binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005293(Antigen peptide transporter 2)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR013305(ABC transporter, ABCB2)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:P36371|reactome:R-MMU-1236974|reactome:R-MMU-983170|refseq:NP_035660.3 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:ZDKMIuISUbt5nfCdizUB1rOvKrw10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P30681 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910056|ensembl:ENSMUSP00000065940|uniprotkb:Q3UXT1|uniprotkb:Q9EQD5 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:hmgb2_mouse(display_long)|uniprotkb:Hmgb2(gene name)|psi-mi:Hmgb2(display_short)|uniprotkb:Hmg2(gene name synonym)|uniprotkb:High mobility group protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:XP_006509587.1|ensembl:ENSMUSG00000054717(gene)|ensembl:ENSMUST00000067925(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032075"(positive regulation of nuclease activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0044378"(non-sequence-specific DNA binding, bending)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR036910|mint:P30681|reactome:R-MMU-140342|refseq:NP_032278.1|dip:DIP-899N - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:z+MIQN4YHLlD59sncgaWv7W9+X010090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q9QZ85 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910173|ensembl:ENSMUSP00000032473|ensembl:ENSMUSP00000063390|ensembl:ENSMUSP00000157568|uniprotkb:Q9Z1M3 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:iigp1_mouse(display_long)|uniprotkb:Iigp1(gene name)|psi-mi:Iigp1(display_short)|uniprotkb:Irga6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:XP_011245279.1|refseq:XP_011245280.1|refseq:XP_011245281.1|refseq:XP_011245282.1|ensembl:ENSMUSG00000054072(gene)|ensembl:ENSMUST00000032473(transcript)|ensembl:ENSMUST00000066912(transcript)|ensembl:ENSMUST00000237185(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006952"(defense response)|go:"GO:0009617"(response to bacterium)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0045087"(innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|interpro:IPR007743(Interferon-inducible GTPase)|interpro:IPR027417|interpro:IPR030385|mint:Q9QZ85|rcsb pdb:1TPZ|rcsb pdb:1TQ2|rcsb pdb:1TQ4|rcsb pdb:1TQ6|rcsb pdb:1TQD|rcsb pdb:4LV5|rcsb pdb:4LV8|rcsb pdb:5FPH|refseq:NP_001139747.1|refseq:NP_068564.4|dip:DIP-58958N - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:ePr0rBCX6hruIUmMboloPvPMuUw10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q3UX10 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910149|ensembl:ENSMUSP00000021639|uniprotkb:B9EJS3 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:tbal3_mouse(display_long)|uniprotkb:Tubal3(gene name)|psi-mi:Tubal3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000021216(gene)|ensembl:ENSMUST00000021639(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q3UX10|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5617833|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|refseq:NP_001029051.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:jbpZr3Dct0cMp2lQFmaEBQO81zI10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q7TPD0 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910093|ensembl:ENSMUSP00000029542|ensembl:ENSMUSP00000071422|uniprotkb:A0A4X0|uniprotkb:A0A4X3|uniprotkb:Q99LK7 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:int3_mouse(display_long)|uniprotkb:Ints3(gene name)|psi-mi:Ints3(display_short)|uniprotkb:SOSS complex subunit A(gene name synonym)|uniprotkb:Sensor of single-strand DNA complex subunit A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000027933(gene)|ensembl:ENSMUST00000029542(transcript)|ensembl:ENSMUST00000071488(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0070876"(SOSS complex)|interpro:IPR019333|mint:Q7TPD0|reactome:R-MMU-6807505|go:"GO:0005634"(nucleus)|refseq:NP_663515.2|refseq:NP_849207.2|dip:DIP-59970N - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:jUWoC4mDiLabdMw+9phBs6h+mTg10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:D3Z7P3 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-2928377|ensembl:ENSMUSP00000110158|uniprotkb:E9PUF0|uniprotkb:Q69ZX9 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:glsk_mouse(display_long)|uniprotkb:Gls(gene name)|psi-mi:Gls(display_short)|uniprotkb:Gls1(gene name synonym)|uniprotkb:Kiaa0838(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000026103(gene)|ensembl:ENSMUST00000114513(transcript)|go:"GO:0001967"(suckling behavior)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0004359"(glutaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0090461"(glutamate homeostasis)|interpro:IPR002110(Ankyrin)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|interpro:IPR020683|interpro:IPR036770|interpro:IPR041541|rcsb pdb:3SS3|rcsb pdb:3SS4|rcsb pdb:3SS5|rcsb pdb:4JKT|rcsb pdb:5W2J|reactome:R-MMU-210500|reactome:R-MMU-5628897|reactome:R-MMU-8964539|refseq:NP_001074550.1|refseq:NP_001106854.1|dip:DIP-60006N - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:Wa7AVXLSYKKwn7woBL0QfUFHIVs10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q9ESU7 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910135|ensembl:ENSMUSP00000104136 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:q9esu7_mouse(display_long)|uniprotkb:Slc1a5(gene name)|psi-mi:Slc1a5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000001918(gene)|ensembl:ENSMUST00000108496(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:1903803"(L-glutamine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|refseq:NP_033227.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:bCxQP81EYq86DSsU3vnApU/B+/g10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:B1ARD6 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6909865|ensembl:ENSMUSP00000044435|ensembl:ENSMUSP00000090515|uniprotkb:A0A0A0MQG6|uniprotkb:Q7TME8|uniprotkb:Q7TME9|uniprotkb:Q80VG8|uniprotkb:Q8C7F7|uniprotkb:Q8CB82 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:slfn9_mouse(display_long)|uniprotkb:Schlafen-9(gene name synonym)|uniprotkb:Slfn9(gene name)|psi-mi:Slfn9(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000069793(gene)|ensembl:ENSMUST00000038211(transcript)|ensembl:ENSMUST00000092840(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR007421(ATPase associated with various cellular activities, AAA-4)|interpro:IPR018647|interpro:IPR027417|interpro:IPR029684|interpro:IPR038461|refseq:NP_766384.2|refseq:XP_006533298.1 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:IgIgkUvUut3tgWbE4v5kBhen0lc10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q8CD98 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6908436 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:q8cd98_mouse(display_long)|uniprotkb:Pfkl(gene name)|psi-mi:Pfkl(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:XP_017169335.1|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR022953|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR035966 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:OH5BMQUUFaSJZauPabILno637Dk10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P47713 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-397673|ensembl:ENSMUSP00000070868 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:pa24a_mouse(display_long)|uniprotkb:Pla2g4a(gene name)|psi-mi:Pla2g4a(display_short)|uniprotkb:Cpla2(gene name synonym)|uniprotkb:Pla2g4(gene name synonym)|uniprotkb:Phospholipase A2 group IVA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_032895.1|ensembl:ENSMUSG00000056220(gene)|ensembl:ENSMUST00000070200(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0002827"(positive regulation of T-helper 1 type immune response)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006640"(monoacylglycerol biosynthetic process)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034478"(phosphatidylglycerol catabolic process)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046456"(icosanoid biosynthetic process)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0046697"(decidualization)|go:"GO:0047498"(calcium-dependent phospholipase A2 activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1902387"(ceramide 1-phosphate binding)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002642(Lysophospholipase, catalytic region)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR035892|interpro:IPR041847|mint:P47713|reactome:R-MMU-111995|reactome:R-MMU-1482788|reactome:R-MMU-1482798|reactome:R-MMU-1482801|reactome:R-MMU-1482839|reactome:R-MMU-1482922|reactome:R-MMU-1482925|reactome:R-MMU-1483115|reactome:R-MMU-1483166|reactome:R-MMU-2142753|reactome:R-MMU-418592|reactome:R-MMU-432142|reactome:R-MMU-6811436 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:3mjUfiApCMI2pQc6LflElRS9vCY10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q9D2Y4 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-5401970|uniprotkb:Q8CIJ5|ensembl:ENSMUSP00000055521 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:mlkl_mouse(display_long)|uniprotkb:Mlkl(gene name)|psi-mi:Mlkl(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_083281.1|refseq:NP_001297542.1|refseq:XP_006531505.1|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0097528"(execution phase of necroptosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036537|rcsb pdb:4BTF|rcsb pdb:4M68|rcsb pdb:4M69|reactome:R-MMU-3295583|reactome:R-MMU-5213460|reactome:R-MMU-5675482|ensembl:ENSMUSG00000012519(gene)|ensembl:ENSMUST00000056157(transcript)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070266"(necroptotic process) - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:psAtDkJEqy995YtXIt+xgMVYHWI10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:O35613 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-77304|uniprotkb:Q9QWT8|uniprotkb:Q9QWV3 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:daxx_mouse(display_long)|uniprotkb:Daxx(gene name)|psi-mi:Daxx(display_short)|uniprotkb:Daxx(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_001186662.1|refseq:NP_031855.3|refseq:XP_006523644.1|refseq:XP_006523645.1|mint:O35613|dip:DIP-30972N|refseq:XP_006523643.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0001741"(XY body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030578"(PML body organization)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|reactome:R-MMU-3899300|reactome:R-MMU-6804757|reactome:R-MMU-9670095 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:/tlUn6VH6raf1J1r07iaYyKarek10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q62036 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-2553752|uniprotkb:B1AXJ0|ensembl:ENSMUSP00000101836 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:cp131_mouse(display_long)|uniprotkb:Cep131(gene name)|psi-mi:Cep131(display_short)|uniprotkb:5-azacytidine-induced protein 1(gene name synonym)|uniprotkb:Az1(gene name synonym)|uniprotkb:Azi(gene name synonym)|uniprotkb:Azi1(gene name synonym)|uniprotkb:Pre-acrosome localization protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_033864.3|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|ensembl:ENSMUSG00000039781(gene)|ensembl:ENSMUST00000106229(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0120212"(sperm head-tail coupling apparatus)|go:"GO:1905198"(manchette assembly)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990953"(intramanchette transport)|interpro:IPR030465|mint:Q62036|refseq:XP_006532124.1 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:SHe8IbjKSkkDb2k8PSeZd8JPhKc10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q9Z2X8 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-647110|uniprotkb:Q3U243|uniprotkb:Q3U8N7|uniprotkb:Q547S3|uniprotkb:Q6ZQI6|uniprotkb:Q8BQY3|ensembl:ENSMUSP00000062467|ensembl:ENSMUSP00000131029|ensembl:ENSMUSP00000141807|ensembl:ENSMUSP00000141840 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:keap1_mouse(display_long)|uniprotkb:Cytosolic inhibitor of Nrf2(gene name synonym)|uniprotkb:Keap1(gene name)|psi-mi:Keap1(display_short)|uniprotkb:Inrf2(gene name synonym)|uniprotkb:Kiaa0132(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_001103775.1|refseq:NP_001103776.1|refseq:NP_001103777.1|refseq:NP_057888.1|dip:DIP-49698N|ensembl:ENSMUSG00000003308(gene)|ensembl:ENSMUST00000049567(transcript)|ensembl:ENSMUST00000164812(transcript)|ensembl:ENSMUST00000193982(transcript)|ensembl:ENSMUST00000194542(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016234"(inclusion body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030563|mint:Q9Z2X8|rcsb pdb:1X2J|rcsb pdb:1X2R|rcsb pdb:2DYH|rcsb pdb:2Z32|rcsb pdb:3ADE|rcsb pdb:3WDZ|rcsb pdb:3WN7|rcsb pdb:4ZY3|rcsb pdb:5CGJ|rcsb pdb:5FNQ|rcsb pdb:5FNR|rcsb pdb:5FNS|rcsb pdb:5FNT|rcsb pdb:5FNU|rcsb pdb:5FZJ|interpro:IPR011705(BTB/Kelch-associated)|rcsb pdb:5FZN|rcsb pdb:6QMC|rcsb pdb:6QMD|rcsb pdb:6QME|rcsb pdb:6QMJ|rcsb pdb:6QMK|rcsb pdb:6ZEW|rcsb pdb:6ZEY|rcsb pdb:6ZEZ|rcsb pdb:6ZF0|rcsb pdb:6ZF1|rcsb pdb:6ZF2|rcsb pdb:6ZF3|rcsb pdb:6ZF4|rcsb pdb:6ZF5|rcsb pdb:6ZF6|rcsb pdb:6ZF7|rcsb pdb:6ZF8|rcsb pdb:7C5E|rcsb pdb:7C60|reactome:R-MMU-5689880|reactome:R-MMU-8932339|reactome:R-MMU-8951664|reactome:R-MMU-983168|rcsb pdb:6ZEX - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:MDyGSGSBs4XgdCc2eeX6YCUdzmY10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:O08749 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-773199|uniprotkb:Q3TG55|uniprotkb:Q3U5W5|uniprotkb:Q3UWP7|uniprotkb:Q99LD3|ensembl:ENSMUSP00000106481 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:dldh_mouse(display_long)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Dld(gene name)|psi-mi:Dld(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_031887.2|ensembl:ENSMUSG00000020664(gene)|ensembl:ENSMUST00000110857(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005929"(cilium)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006508"(proteolysis)|go:"GO:0007369"(gastrulation)|go:"GO:0007568"(aging)|go:"GO:0009106"(lipoate metabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043159"(acrosomal matrix)|go:"GO:0043209"(myelin sheath)|go:"GO:0043544"(lipoamide binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051068"(dihydrolipoamide metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0106077"(histone succinylation)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|mint:O08749|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-6783984|reactome:R-MMU-70268|reactome:R-MMU-70895|reactome:R-MMU-71064|reactome:R-MMU-71403 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:6j/8rw4lkNMW4Lo5sGoRdDJBk2w10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q61735 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-494286|uniprotkb:Q921Z2 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:cd47_mouse(display_long)|uniprotkb:Integrin-associated protein(gene name synonym)|uniprotkb:Cd47(gene name)|psi-mi:Cd47(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_034711.1|interpro:IPR013147(CD47 transmembrane)|interpro:IPR013270(CD47 immunoglobulin-like)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:XP_006521874.1|reactome:R-MMU-202733|reactome:R-MMU-216083|reactome:R-MMU-391160|interpro:IPR006704(CD47 integrin associated protein)|reactome:R-MMU-6798695|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0008228"(opsonization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032653"(regulation of interleukin-10 production)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0035696"(monocyte extravasation)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070487"(monocyte aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071349"(cellular response to interleukin-12)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904669"(ATP export)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR037805 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:AnttsmD0TOll60srfvDk0KAdGLI10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q8CCF0 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6909928|ensembl:ENSMUSP00000008517|uniprotkb:E9QPM6|uniprotkb:Q6P7X2|uniprotkb:Q8BQ91|uniprotkb:Q8C8U4|uniprotkb:Q8C8V5|uniprotkb:Q8CCG6|uniprotkb:Q8CF52|uniprotkb:Q8VBW3 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:prp31_mouse(display_long)|uniprotkb:Prpf31(gene name)|psi-mi:Prpf31(display_short)|uniprotkb:Prp31(gene name synonym)|uniprotkb:Pre-mRNA-processing factor 31(gene name synonym)|uniprotkb:U4/U6 snRNP 61 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000008373(gene)|ensembl:ENSMUST00000008517(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005690"(U4atac snRNP)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070990"(snRNP binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071166"(ribonucleoprotein complex localization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012976(NOSIC)|interpro:IPR019175|interpro:IPR027105|interpro:IPR036070|interpro:IPR042239|mint:Q8CCF0|reactome:R-MMU-72163|refseq:NP_001153186.1|refseq:NP_081604.3 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:9olqPQHnMUdgGJ1roLcvwZcI7SE10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q99K01 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6909991|uniprotkb:Q3TCL3|uniprotkb:Q3TN13|uniprotkb:Q8BMK9|uniprotkb:Q8BW02|uniprotkb:Q8BW51|uniprotkb:Q8BZZ4|uniprotkb:Q9DC25 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:pdxd1_mouse(display_long)|uniprotkb:Pdxdc1(gene name)|psi-mi:Pdxdc1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_001277946.1|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008117"(sphinganine-1-phosphate aldolase activity)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|refseq:NP_001034622.1|refseq:NP_444411.2|mint:Q99K01 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:MqmpBly7g1D61y1iA3hjz3zyWlU10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q9R099 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6909876|ensembl:ENSMUSP00000115011|uniprotkb:Q8CFY0 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:tbl2_mouse(display_long)|uniprotkb:Tbl2(gene name)|psi-mi:Tbl2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000005374(gene)|ensembl:ENSMUST00000153183(transcript)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR042410|go:"GO:0005783"(endoplasmic reticulum)|mint:Q9R099|refseq:NP_038791.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:0qrlWKNnxyiEUGLpi1R3tfHmInw10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q9Z0E6 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6909837|ensembl:ENSMUSP00000132435|uniprotkb:Q4FK03|uniprotkb:Q8CIC6|uniprotkb:Q921N2|uniprotkb:Q9R1I0 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:gbp2_mouse(display_long)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)|uniprotkb:Gbp2(gene name)|psi-mi:Gbp2(display_short)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000028270(gene)|ensembl:ENSMUST00000165774(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009617"(response to bacterium)|go:"GO:0020005"(symbiont-containing vacuole membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q9Z0E6|go:"GO:0003924"(GTPase activity)|refseq:NP_034390.1 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:Fa/gXTBkiG0hTxS51ahbnensmC010090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q8BQ30 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-647515|uniprotkb:Q3UDS6|uniprotkb:Q8CEY9|uniprotkb:Q8R3D8|uniprotkb:B8JJ63|uniprotkb:B8JJ64|ensembl:ENSMUSP00000109445|ensembl:ENSMUSP00000116100|ensembl:ENSMUSP00000120343|ensembl:ENSMUSP00000141094 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:ppr18_mouse(display_long)|uniprotkb:Ppp1r18(gene name)|psi-mi:Ppp1r18(display_short)|uniprotkb:Protein phosphatase 1 F-actin cytoskeleton-targeting subunit(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 18(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_001140182.1|refseq:NP_001140183.1|refseq:NP_780451.1|refseq:XP_006525155.2|ensembl:ENSMUSG00000034595(gene)|ensembl:ENSMUST00000113814(transcript)|ensembl:ENSMUST00000122899(transcript)|ensembl:ENSMUST00000144382(transcript)|ensembl:ENSMUST00000187690(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019902"(phosphatase binding)|interpro:IPR025903|interpro:IPR025907|interpro:IPR026671 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:usvpwQopl2n2MPy/P62eExXBRXY10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P70227 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910019|ensembl:ENSMUSP00000038150|uniprotkb:Q5DWM4|uniprotkb:Q8CED5|uniprotkb:Q91Z08 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:itpr3_mouse(display_long)|uniprotkb:Itpr3(gene name)|psi-mi:Itpr3(display_short)|uniprotkb:IP3 receptor isoform 3(gene name synonym)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0098793"(presynapse)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|rcsb pdb:3JRR|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-5578775|reactome:R-MMU-983695|ensembl:ENSMUSG00000042644(gene)|ensembl:ENSMUST00000049308(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007613"(memory)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|refseq:NP_542120.2 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:/rO5sZ0rWGGYvxB/Erfrr4wF/xY10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q3UPN1 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6909889|ensembl:ENSMUSP00000029574 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:q3upn1_mouse(display_long)|uniprotkb:Vcam1(gene name)|psi-mi:Vcam1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000027962(gene)|ensembl:ENSMUST00000029574(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002102"(podosome)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005902"(microvillus)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008131"(primary amine oxidase activity)|go:"GO:0009308"(amine metabolic process)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030175"(filopodium)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035094"(response to nicotine)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0045177"(apical part of cell)|go:"GO:0045471"(response to ethanol)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060384"(innervation)|go:"GO:0060945"(cardiac neuron differentiation)|go:"GO:0071065"(alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0140039"(cell-cell adhesion in response to extracellular stimulus)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR003989(Vascular cell adhesion molecule-1)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008424(Immunoglobulin C2-set)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035823.3 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:X/z6wY1+lKuLmeEXoMYZ+PqvauI10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q62293 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6909815|uniprotkb:Q60711|uniprotkb:Q8BN19|ensembl:ENSMUSP00000045025|ensembl:ENSMUSP00000069914 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:tgtp1_mouse(display_long)|uniprotkb:Tgtp1(gene name)|psi-mi:Tgtp1(display_short)|uniprotkb:Ifggb5(gene name synonym)|uniprotkb:Interferon-gamma-inducible GTPase Ifggb5(gene name synonym)|uniprotkb:Irgb6(gene name synonym)|uniprotkb:Mg21(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000078921(gene)|ensembl:ENSMUSG00000078922(gene)|ensembl:ENSMUST00000046745(transcript)|ensembl:ENSMUST00000068063(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0009615"(response to virus)|go:"GO:0009617"(response to bacterium)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|interpro:IPR007743(Interferon-inducible GTPase)|interpro:IPR027417|interpro:IPR030385|mint:Q62293|refseq:NP_001138636.1|refseq:NP_035709.3 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:eqMeNZzg2cFqn6ZJtGfCbfKhNOQ10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P05064 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-494220|ensembl:ENSMUSP00000032934|ensembl:ENSMUSP00000101955 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:aldoa_mouse(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Aldolase 1(gene name synonym)|uniprotkb:Aldoa(gene name)|psi-mi:Aldoa(display_short)|uniprotkb:Aldo1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:XP_006507273.1|refseq:XP_006507274.1|refseq:NP_001170779.1|refseq:NP_031464.1|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061827"(sperm head)|go:"GO:0005886"(plasma membrane)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|ensembl:ENSMUSG00000030695(gene)|ensembl:ENSMUST00000032934(transcript)|ensembl:ENSMUST00000106348(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0002020"(protease binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|mint:P05064|reactome:R-MMU-114608|reactome:R-MMU-6798695|reactome:R-MMU-70171|reactome:R-MMU-70263|interpro:IPR029768 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:m116/AX8vWkh1JCGOnEZv9ZOU9010090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:Q9Z1M2 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6909967|ensembl:ENSMUSP00000056001|ensembl:ENSMUSP00000104464|uniprotkb:E9PVI2 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:q9z1m2_mouse(display_long)|uniprotkb:Irgm2(gene name)|psi-mi:Irgm2(display_short)|uniprotkb:AI481100(gene name synonym)|uniprotkb:GTPI(gene name synonym)|uniprotkb:Ifggd2(gene name synonym)|uniprotkb:Iigp2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6909752|imex:IM-21243-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 ensembl:ENSMUSG00000069874(gene)|ensembl:ENSMUST00000058704(transcript)|ensembl:ENSMUST00000108836(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006952"(defense response)|go:"GO:0009617"(response to bacterium)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0050700"(CARD domain binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0061762"(CAMKK-AMPK signaling cascade)|go:"GO:0020003"(symbiont-containing vacuole)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0098586"(cellular response to virus)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR007743(Interferon-inducible GTPase)|interpro:IPR027417|interpro:IPR030385|refseq:NP_062313.3 - - - agonist:DNA|figure legend:Table S4, Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2018/07/05 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:TI8uXOJolqbHYbXH47yJ+mlJqag10090 intact-crc:03485C220240F844|rigid:D/qFKcx/+owIIgPOnBmafPU/YAs false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q69ZN7 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-1994301|uniprotkb:Q8BU64|uniprotkb:Q8BU70|uniprotkb:Q8BUC1|uniprotkb:Q8C0D1|uniprotkb:Q7TMG0|uniprotkb:Q80V33|uniprotkb:Q8BVY6|uniprotkb:Q8R3B4|ensembl:ENSMUSP00000045036 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:myof_mouse(display_long)|uniprotkb:Myof(gene name)|psi-mi:Myof(display_short)|uniprotkb:Kiaa1207(gene name synonym)|uniprotkb:Fer1l3(gene name synonym)|uniprotkb:Fer-1-like protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001093104.1|refseq:NP_001289069.1|ensembl:ENSMUSG00000048612(gene)|ensembl:ENSMUST00000041475(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007520"(myoblast fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030947"(regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0061025"(membrane fusion)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR012560(FerA)|interpro:IPR012561(FerB)|interpro:IPR012968(FerI)|interpro:IPR029999|interpro:IPR032362|interpro:IPR035892|interpro:IPR037720|interpro:IPR037721|interpro:IPR037722|interpro:IPR037723|interpro:IPR037724|interpro:IPR037725|interpro:IPR037726|mint:Q69ZN7|go:"GO:0001778"(plasma membrane repair) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:FQq1tTfF2Sam8Ae+7rdqAtdvLuk10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q99PL5 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-8361659|uniprotkb:Q99PK6|uniprotkb:Q99PK8|uniprotkb:Q9CS20|uniprotkb:Q99PL4|uniprotkb:Q99PK9|uniprotkb:Q99PL0|intact:MINT-1867743|uniprotkb:Q99PL1|uniprotkb:Q99PL3|uniprotkb:Q99PK7|uniprotkb:Q99PK5|uniprotkb:Q99PL2|uniprotkb:A2AVJ8 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:rrbp1_mouse(display_long)|uniprotkb:Rrbp1(gene name)|psi-mi:Rrbp1(display_short)|uniprotkb:Ribosome receptor protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) interpro:IPR040248|refseq:NP_077243.2|refseq:NP_598329.1|mint:Q99PL5|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|interpro:IPR007794(Ribosome receptor lysine or proline rich) - - comment:mint|function:Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:HSI1U7KA5w2yF41srMqdcd1FM6s10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9CWP6 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-8392111|uniprotkb:Q8BYF8|uniprotkb:Q8R0T7|uniprotkb:Q8BZB6|intact:MINT-4125553|uniprotkb:Q8C0G1 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:mspd2_mouse(display_long)|uniprotkb:Mospd2(gene name)|psi-mi:Mospd2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) interpro:IPR008962(PapD-like)|refseq:NP_001277452.1|refseq:NP_001277453.1|refseq:NP_084006.2|interpro:IPR013783(Immunoglobulin-like fold)|mint:Q9CWP6|interpro:IPR036273|interpro:IPR036865|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|rcsb pdb:1WIC|reactome:R-MMU-6798695|reactome:R-MMU-9013405|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal) - - comment:mint figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:MimcE2OD6iRPAfTjYZOlAt2valE10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:P23249 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-8429153|uniprotkb:Q9DC64|intact:MINT-4102260|ensembl:ENSMUSP00000128246 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:mov10_mouse(display_long)|uniprotkb:Mov10(gene name)|psi-mi:Mov10(display_short)|uniprotkb:Gb110(gene name synonym)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001156913.1|refseq:NP_032645.2|refseq:NP_001156912.1|refseq:XP_006501163.1|refseq:XP_006501164.1|dip:DIP-48575N|ensembl:ENSMUSG00000002227(gene)|ensembl:ENSMUST00000168015(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|mint:P23249|go:"GO:0043186"(P granule) - - comment:mint|function:May be an helicase with an important function in development and/or control of cell proliferation figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:DYetyAovfa6MAvuugGR4bF/qd8c10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:P27046 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-8384167|uniprotkb:B9EHS6|intact:MINT-1864531|ensembl:ENSMUSP00000083928 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:ma2a1_mouse(display_long)|uniprotkb:Man2a1(gene name)|psi-mi:Man2a1(display_short)|uniprotkb:Mana2(gene name synonym)|uniprotkb:Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase(gene name synonym)|uniprotkb:Golgi alpha-mannosidase II(gene name synonym)|uniprotkb:Mannosidase alpha class 2A member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_032575.2|ensembl:ENSMUSG00000024085(gene)|ensembl:ENSMUST00000086723(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0004559"(alpha-mannosidase activity)|go:"GO:0004572"(mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0015923"(mannosidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016799"(hydrolase activity, hydrolyzing N-glycosyl compounds)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048286"(lung alveolus development)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|interpro:IPR000602(Glycoside hydrolase, family 38, core)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR011682(Glycosyl hydrolases 38, C-terminal)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR015341(Glycoside hydrolase, family 38, central region)|interpro:IPR027291|interpro:IPR028995|interpro:IPR037094|mint:P27046|reactome:R-MMU-975578 - - comment:mint|function:Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:iwTz1khCeeDIFsoG4q/CiE/t47810090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:P46978 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-8429667|intact:MINT-4135975|ensembl:ENSMUSP00000113116 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:stt3a_mouse(display_long)|uniprotkb:Stt3a(gene name)|psi-mi:Stt3a(display_short)|uniprotkb:Itm1(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_032434.3|ensembl:ENSMUSG00000032116(gene)|ensembl:ENSMUST00000120381(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035000"(oligosaccharyltransferase III complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:P46978 - - function:"Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity"|comment:mint figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:EksTHlmWOlqu2PCDRKBMbD8pPPw10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q6NZJ6 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-8175606|uniprotkb:Q6NZN8|uniprotkb:Q8BW99|intact:MINT-1856450|ensembl:ENSMUSP00000047678|ensembl:ENSMUSP00000111120 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:if4g1_mouse(display_long)|uniprotkb:Eif4g1(gene name)|psi-mi:Eif4g1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001291361.1|refseq:NP_666053.2|refseq:XP_006522000.1|dip:DIP-42771N|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|reactome:R-MMU-975957|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q6NZJ6|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-166208|reactome:R-MMU-429947|reactome:R-MMU-450408|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|ensembl:ENSMUSG00000045983(gene)|ensembl:ENSMUST00000044783(transcript)|ensembl:ENSMUST00000115460(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process) - - comment:mint|function:Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:91tJB28zzWTM77Jg0kZ18KIUhmo10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q2EMV9 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-1534943|uniprotkb:Q571C6|uniprotkb:Q8BN35|uniprotkb:Q8VDT6|uniprotkb:E9QP48|ensembl:ENSMUSP00000037657 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:par14_mouse(display_long)|uniprotkb:Parp14(gene name)|psi-mi:Parp14(display_short)|uniprotkb:Kiaa1268(gene name synonym)|uniprotkb:Collaborator of STAT6(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 8(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 14(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001034619.2|dip:DIP-38053N|ensembl:ENSMUSG00000034422(gene)|ensembl:ENSMUST00000042665(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045087"(innate immune response)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070403"(NAD+ binding)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1902216"(positive regulation of interleukin-4-mediated signaling pathway)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034517|interpro:IPR037197|interpro:IPR043472|rcsb pdb:1X4R|reactome:R-MMU-197264 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:B38McmWStIPDwecAtDvlqFQswGg10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q3TNL8 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908069|ensembl:ENSMUSP00000093697|uniprotkb:Q3TAD9|uniprotkb:Q3TB01|uniprotkb:Q571G7|uniprotkb:Q6P400 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:ipri_mouse(display_long)|uniprotkb:Itprip(gene name)|psi-mi:Itprip(display_short)|uniprotkb:Kiaa1754(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000117975(gene)|ensembl:ENSMUST00000095998(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR024797|interpro:IPR024810|interpro:IPR026250|refseq:XP_006527237.1|refseq:XP_006527238.1|refseq:NP_001001738.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:pnCktgjY6yfesT4SNl5ZzQklGb010090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:A2AT37 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908270|ensembl:ENSMUSP00000058375 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:rent2_mouse(display_long)|uniprotkb:Up-frameshift suppressor 2 homolog(gene name synonym)|uniprotkb:Upf2(gene name)|psi-mi:Upf2(display_short)|uniprotkb:Nonsense mRNA reducing factor 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000043241(gene)|ensembl:ENSMUST00000060092(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR007193(Up-frameshift suppressor 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039762|reactome:R-MMU-975957|refseq:XP_006497548.1|refseq:NP_001074601.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:d4lV7GMr90nya368PK+/S2SfxJ410090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q6P4T2 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6878408|ensembl:ENSMUSP00000099509|uniprotkb:Q69ZZ3 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:u520_mouse(display_long)|uniprotkb:Snrnp200(gene name)|psi-mi:Snrnp200(display_short)|uniprotkb:Kiaa0788(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000003660(gene)|ensembl:ENSMUST00000103220(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|mint:Q6P4T2|reactome:R-MMU-72163|reactome:R-MMU-72165|refseq:NP_796188.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:P0APWhAjy05E6VYhOWEmHdw2QHw10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q6PD26 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908000|ensembl:ENSMUSP00000044871 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:pigs_mouse(display_long)|uniprotkb:Pigs(gene name)|psi-mi:Pigs(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000041958(gene)|ensembl:ENSMUST00000048073(transcript)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-MMU-162791|refseq:NP_958808.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:ljxpCrQW3mFjmNGViudu3boVs+410090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q3UPH7 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908622|ensembl:ENSMUSP00000091331|ensembl:ENSMUSP00000138635|uniprotkb:Q3U1X1|uniprotkb:Q3UGT7|uniprotkb:Q3UYX3|uniprotkb:Q6KAS1|uniprotkb:Q6PD04|uniprotkb:Q6PDY3 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:arh40_mouse(display_long)|uniprotkb:Arhgef40(gene name)|psi-mi:Arhgef40(display_short)|uniprotkb:Solo(gene name synonym)|uniprotkb:Protein SOLO(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000004562(gene)|ensembl:ENSMUST00000093813(transcript)|ensembl:ENSMUST00000182909(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013106|refseq:XP_006519107.1|refseq:XP_006519109.1|refseq:NP_001139393.1|refseq:NP_001139394.1|refseq:NP_937892.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:PEETTYWCQbAzgjZcjNWAWQSuUBQ10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q8BFZ9 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-1635049|uniprotkb:Q8BML8|ensembl:ENSMUSP00000033873 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:erln2_mouse(display_long)|uniprotkb:Erlin2(gene name)|psi-mi:Erlin2(display_short)|uniprotkb:Spfh2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_705820.1|refseq:XP_006509179.1|refseq:XP_006509180.1|ensembl:ENSMUSG00000031483(gene)|ensembl:ENSMUST00000033873(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:Q8BFZ9|reactome:R-MMU-382556 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:/OxFugzl4zprvnZbqOGcXmUe3ao10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:A8C756 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6907594|ensembl:ENSMUSP00000041701|uniprotkb:Q3TDR4|uniprotkb:Q3U2L1|uniprotkb:Q69ZA8|uniprotkb:Q7TPV7|uniprotkb:Q8C8S7 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:thada_mouse(display_long)|uniprotkb:Thada(gene name)|psi-mi:Thada(display_short)|uniprotkb:Kiaa1767(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:XP_017172962.1|refseq:XP_006524339.1|ensembl:ENSMUSG00000024251(gene)|ensembl:ENSMUST00000047524(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0055088"(lipid homeostasis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019442|refseq:NP_898842.2|refseq:XP_006524337.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:AxMAd/M0dyepBY28Uc0N2p2AwV810090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:D4AFX7 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-10729612|ensembl:ENSMUSP00000139804 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:d4afx7_mouse(display_long)|uniprotkb:Dnajc13(gene name)|psi-mi:Dnajc13(display_short)|uniprotkb:RME-8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:XP_006511771.1|ensembl:ENSMUSG00000032560(gene)|ensembl:ENSMUST00000186788(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|go:"GO:1902954"(regulation of early endosome to recycling endosome transport)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025640|interpro:IPR035445|interpro:IPR036869|reactome:R-MMU-6798695|go:"GO:0010008"(endosome membrane) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:x7JrboPFDyZPFyFIY1gJoKV1zgE10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q3UJB9 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-2553526|uniprotkb:Q3U6U8|uniprotkb:Q8R223|uniprotkb:Q7TS78 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:edc4_mouse(display_long)|uniprotkb:Edc4(gene name)|psi-mi:Edc4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|reactome:R-MMU-430039|refseq:NP_001288029.1|interpro:IPR032401|refseq:NP_853625.1|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|mint:Q3UJB9 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:FVX5K/2axUrzI66j1QPmJsqpxec10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q6ZQ08 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-682479|intact:EBI-2104684|uniprotkb:B2RY28|uniprotkb:Q3UPB7|uniprotkb:Q8BSB4|uniprotkb:Q8BXB2|uniprotkb:Q8C0H2|uniprotkb:Q8K3D8 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:cnot1_mouse(display_long)|uniprotkb:Cnot1(gene name)|psi-mi:Cnot1(display_short)|uniprotkb:Kiaa1007(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_835179.1|refseq:XP_006530937.1|dip:DIP-46845N|mint:Q6ZQ08|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|reactome:R-MMU-429947|reactome:R-MMU-6804115 - - comment:AfCS Y2H protein 39306. Translated from nucleotide sequence. figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:2Q4quoSuPlUbD4QkiAkc9Hr9avI10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q7TQH0 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908203|ensembl:ENSMUSP00000035415|uniprotkb:Q80XN9|uniprotkb:Q8K059 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:atx2l_mouse(display_long)|uniprotkb:Atxn2l(gene name)|psi-mi:Atxn2l(display_short)|uniprotkb:A2lp(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:XP_006507788.1|ensembl:ENSMUSG00000032637(gene)|ensembl:ENSMUST00000040202(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q7TQH0|refseq:NP_898841.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:7v7iuPRti2err2QrmJIGoWqEM3U10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9EPL8 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-2550269|ensembl:ENSMUSP00000081782|uniprotkb:Q7TN09|uniprotkb:Q7TQ63|uniprotkb:Q8BKD8|uniprotkb:Q8BYI0 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:ipo7_mouse(display_long)|uniprotkb:Ipo7(gene name)|psi-mi:Ipo7(display_short)|uniprotkb:Ranbp7(gene name synonym)|uniprotkb:Ran-binding protein 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000066232(gene)|ensembl:ENSMUST00000084731(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9EPL8|refseq:NP_852658.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:YOGtbOzeE6Oq5T0J42GWW7fH9H010090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q6PIC6 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-769101|ensembl:ENSMUSP00000079691 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:at1a3_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-3(gene name synonym)|uniprotkb:"Na(+)/K(+) ATPase alpha(III) subunit"(gene name synonym)|uniprotkb:Atp1a3(gene name)|psi-mi:Atp1a3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001277398.1|ensembl:ENSMUSG00000040907(gene)|ensembl:ENSMUST00000080882(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0016020"(membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030424"(axon)|go:"GO:0031090"(organelle membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|reactome:R-MMU-936837|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086037"("P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential")|go:"GO:0098794"(postsynapse)|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099520"(ion antiporter activity involved in regulation of presynaptic membrane potential)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIC6|go:"GO:0045202"(synapse)|reactome:R-MMU-5578775 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:1sz4qkpfVGTvDfvmBVIE3wsH2Rs10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q8BWZ3 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908521|ensembl:ENSMUSP00000038977|uniprotkb:A1A4B7|uniprotkb:Q3KQI7|uniprotkb:Q3TJC6|uniprotkb:Q7TMM2 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:naa25_mouse(display_long)|uniprotkb:Naa25(gene name)|psi-mi:Naa25(display_short)|uniprotkb:Mdm20(gene name synonym)|uniprotkb:Mitochondrial distribution and morphology protein 20(gene name synonym)|uniprotkb:N-terminal acetyltransferase B complex subunit MDM20(gene name synonym)|uniprotkb:N-terminal acetyltransferase B complex subunit NAA25(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000042719(gene)|ensembl:ENSMUST00000042163(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0031416"(NatB complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019183|refseq:NP_766310.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:puxV47+knwRMrLDIhgpI1qjAzW810090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:E9PVA8 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-4284669|intact:EBI-6908505|uniprotkb:B2RWW6|ensembl:ENSMUSP00000069432 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:gcn1_mouse(display_long)|uniprotkb:Gcn1(gene name)|psi-mi:Gcn1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:Gcn1l1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_766307.2|ensembl:ENSMUSG00000041638(gene)|ensembl:ENSMUST00000064454(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:E9PVA8 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:KX5ViHlt2ZOUAv/9GRSRAMijpE010090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q8C7X2 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-776290|uniprotkb:Q3TCG4|uniprotkb:Q6ZQJ4|uniprotkb:Q8K3W8|uniprotkb:B2RTJ5|ensembl:ENSMUSP00000137103 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:emc1_mouse(display_long)|uniprotkb:Emc1(gene name)|psi-mi:Emc1(display_short)|uniprotkb:Kiaa0090(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001034289.1|refseq:NP_666269.2|ensembl:ENSMUSG00000078517(gene)|ensembl:ENSMUST00000179784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032977"(membrane insertase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8C7X2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:3y6bRQmyXFtytQSpnHtVy5a8wag10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q569Z6 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-2536252|ensembl:ENSMUSP00000079722 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:tr150_mouse(display_long)|uniprotkb:Thrap3(gene name)|psi-mi:Thrap3(display_short)|uniprotkb:Trap150(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 150 kDa component(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000043962(gene)|ensembl:ENSMUST00000080919(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR026667|interpro:IPR029199|go:"GO:0008380"(RNA splicing)|refseq:XP_011238805.1|refseq:NP_666265.3|refseq:XP_006503104.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:Cb0vHuEX3Ew27z2gvfC/36tdeYE10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q3UU96 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-10729569|uniprotkb:B2RY49|uniprotkb:Q4V9U7|uniprotkb:Q6ZQA9|uniprotkb:Q8R495|ensembl:ENSMUSP00000095059 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:mrcka_mouse(display_long)|uniprotkb:CDC42-binding protein kinase alpha(gene name synonym)|uniprotkb:Cdc42bpa(gene name)|psi-mi:Cdc42bpa(display_short)|uniprotkb:Kiaa0451(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001333733.1|ensembl:ENSMUSG00000026490(gene)|ensembl:ENSMUST00000097450(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0016477"(cell migration)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014930(DMPK coiled coil)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR026611|interpro:IPR031597|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:Gwxi5/9sLhSU4uqjoMrwxzv0yoU10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:E9QKZ2 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908404|ensembl:ENSMUSP00000036093 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:e9qkz2_mouse(display_long)|uniprotkb:Ipo9(gene name)|psi-mi:Ipo9(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000041879(gene)|ensembl:ENSMUST00000041023(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_722469.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:Smxb8GS41vMYM+Kj8+Idj++qkwo10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9CY50 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-772508|uniprotkb:Q3TIM3|uniprotkb:Q99MP2|ensembl:ENSMUSP00000021864 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:ssra_mouse(display_long)|uniprotkb:Signal sequence receptor subunit alpha(gene name synonym)|uniprotkb:Ssr1(gene name)|psi-mi:Ssr1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_080241.3|ensembl:ENSMUSG00000021427(gene)|ensembl:ENSMUST00000021864(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005595("Translocon-associated protein (TRAP), alpha subunit") - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:Ml+B+X8QgKftV7+u0eo1td8E9E010090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q8CGC7 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-4285489|uniprotkb:Q3UFJ2|uniprotkb:Q4VC16|uniprotkb:E9QKC4|ensembl:ENSMUSP00000045841 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:syep_mouse(display_long)|uniprotkb:Eprs(gene name synonym)|uniprotkb:Qprs(gene name synonym)|uniprotkb:Eprs1(gene name)|psi-mi:Eprs1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_084011.1|ensembl:ENSMUSG00000026615(gene)|ensembl:ENSMUST00000046514(transcript)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0140212"(regulation of long-chain fatty acid import into cell)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|mint:Q8CGC7|interpro:IPR004046(Glutathione S-transferase, C-terminal) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:uFcCD59N912Lvyf6/OxGsROezcU10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q5SWU9 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-773043|uniprotkb:A2A6H4|uniprotkb:Q5SWU6|uniprotkb:Q5SWU7|uniprotkb:Q5SWU8|uniprotkb:Q6JIZ1|uniprotkb:Q6PHL9|uniprotkb:Q705X8|uniprotkb:Q705X9|uniprotkb:Q91VC8|uniprotkb:Q925C4|uniprotkb:Q925C5|ensembl:ENSMUSP00000020843|ensembl:ENSMUSP00000099490 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:acaca_mouse(display_long)|uniprotkb:ACC-alpha(gene name synonym)|uniprotkb:Acetyl-CoA carboxylase 265(gene name synonym)|uniprotkb:Acaca(gene name)|psi-mi:Acaca(display_short)|uniprotkb:Acac(gene name synonym)|uniprotkb:Gm738(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:XP_011246969.1|refseq:NP_579938.2|refseq:XP_006532016.1|refseq:XP_006532017.1|refseq:XP_006532018.1|refseq:XP_006532019.1|refseq:XP_006532020.1|dip:DIP-32276N|ensembl:ENSMUSG00000020532(gene)|ensembl:ENSMUST00000020843(transcript)|ensembl:ENSMUST00000103201(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0009374"(biotin binding)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019538"(protein metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|mint:Q5SWU9|reactome:R-MMU-163765|reactome:R-MMU-196780|reactome:R-MMU-200425|reactome:R-MMU-75105 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:VfXewZAby/B32mkiYMpokapdv1k10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:E9QAE3 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6907550|ensembl:ENSMUSP00000097093 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:e9qae3_mouse(display_long)|uniprotkb:Btaf1(gene name)|psi-mi:Btaf1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022707|interpro:IPR027417|interpro:IPR038718|interpro:IPR044078|go:"GO:0035562"(negative regulation of chromatin binding)|ensembl:ENSMUSG00000040565(gene)|ensembl:ENSMUST00000099494(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|refseq:NP_001074175.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:M70HomtjGg8JB3BcoUmR1Bb3L3Q10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q6P5B0 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-10729550|uniprotkb:Q7TMI5|uniprotkb:Q80TU2|ensembl:ENSMUSP00000039853 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:rrp12_mouse(display_long)|uniprotkb:Rrp12(gene name)|psi-mi:Rrp12(display_short)|uniprotkb:Kiaa0690(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_955518.1|ensembl:ENSMUSG00000035049(gene)|ensembl:ENSMUST00000038677(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012978(Region of unknown function, NUC173)|interpro:IPR016024(Armadillo-type fold) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:DsiG9p8Mo/80hbXxuUtx1xfsDEU10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q80U72 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-1766028|uniprotkb:Q6P5H7|uniprotkb:Q7TPH8|uniprotkb:Q80VB1|uniprotkb:Q8CI48|uniprotkb:Q8VII1|uniprotkb:Q922S3|ensembl:ENSMUSP00000068056 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:scrib_mouse(display_long)|uniprotkb:Scrib(gene name)|psi-mi:Scrib(display_short)|uniprotkb:Kiaa0147(gene name synonym)|uniprotkb:Lap4(gene name synonym)|uniprotkb:Scrib1(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_598850.1|refseq:XP_017171844.1|refseq:NP_001297471.1|refseq:NP_001297472.1|dip:DIP-40660N|ensembl:ENSMUSG00000022568(gene)|ensembl:ENSMUST00000063747(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008104"(protein localization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042060"(wound healing)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q80U72|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9696264|reactome:R-MMU-9696270 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:WF4b5QAjIGIgq6tnexNZtDhI7gk10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q91YQ5 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-642977|uniprotkb:Q3U985|ensembl:ENSMUSP00000032143 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:rpn1_mouse(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)|uniprotkb:Rpn1(gene name)|psi-mi:Rpn1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_598694.3|ensembl:ENSMUSG00000030062(gene)|ensembl:ENSMUST00000032143(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:Q91YQ5 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:fkMLaj/vo2SbXmURvjhv896RtZ410090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q8BH79 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6907615|ensembl:ENSMUSP00000045214|uniprotkb:Q4FZD2|uniprotkb:Q8BMS8|uniprotkb:Q8BV74|uniprotkb:Q8BW67|uniprotkb:Q8R0U0|uniprotkb:Q99LP0 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:ano10_mouse(display_long)|uniprotkb:Ano10(gene name)|psi-mi:Ano10(display_short)|uniprotkb:Tmem16k(gene name synonym)|uniprotkb:Transmembrane protein 16K(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:XP_011241230.1|ensembl:ENSMUSG00000037949(gene)|ensembl:ENSMUST00000042546(transcript)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005229"(intracellular calcium activated chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006821"(chloride transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055085"(transmembrane transport)|interpro:IPR007632(Protein of unknown function DUF590)|interpro:IPR031291|reactome:R-MMU-2672351|refseq:NP_001258802.1|refseq:NP_598740.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:ErWHRReVlFxkZOvw7kHDXHHrX+U10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:E9Q7G0 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6907852|uniprotkb:Q80Y35|ensembl:ENSMUSP00000081912 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:numa1_mouse(display_long)|uniprotkb:Numa1(gene name)|psi-mi:Numa1(display_short)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000066306(gene)|ensembl:ENSMUST00000084852(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|refseq:XP_006507240.1|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|reactome:R-MMU-380320|reactome:R-MMU-68875|refseq:NP_598708.3 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:/yOsUga+jQmWlhNoGSJ78OsbPI810090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:A2ANY6 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-10729525|ensembl:ENSMUSP00000071569 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:a2any6_mouse(display_long)|uniprotkb:Mdn1(gene name)|psi-mi:Mdn1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:XP_006537539.1|ensembl:ENSMUSG00000058006(gene)|ensembl:ENSMUST00000071642(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0045111"(intermediate filament cytoskeleton)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR012099(Midasin)|interpro:IPR027417|interpro:IPR029317|interpro:IPR036465|interpro:IPR040848|interpro:IPR041190 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:bn5lDptrXf2XbvZt9Br/IYoH9KY10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q99MR6 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908591|ensembl:ENSMUSP00000043123|uniprotkb:Q3UD04|uniprotkb:Q5D042|uniprotkb:Q8VEE6|uniprotkb:Q99MR4|uniprotkb:Q99MR5|uniprotkb:Q99MR7 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:srrt_mouse(display_long)|uniprotkb:Srrt(gene name)|psi-mi:Srrt(display_short)|uniprotkb:Ars2(gene name synonym)|uniprotkb:Asr2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:XP_006504692.1|ensembl:ENSMUSG00000037364(gene)|ensembl:ENSMUST00000040873(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007042(Arsenite-resistance protein 2)|interpro:IPR021933|interpro:IPR035979|interpro:IPR039727|mint:Q99MR6|reactome:R-MMU-6807505|reactome:R-MMU-72163|refseq:NP_001103379.1|refseq:NP_001103380.1|refseq:NP_113582.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:bN5sDa7ldVbikff0n+wySOIeGrE10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9EP69 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908224|ensembl:ENSMUSP00000026270|ensembl:ENSMUSP00000158880|uniprotkb:Q80TQ1|uniprotkb:Q99K33 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:sac1_mouse(display_long)|uniprotkb:Sacm1l(gene name)|psi-mi:Sacm1l(display_short)|uniprotkb:Kiaa0851(gene name synonym)|uniprotkb:Sac1(gene name synonym)|uniprotkb:Suppressor of actin mutations 1-like protein(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000025240(gene)|ensembl:ENSMUST00000026270(transcript)|ensembl:ENSMUST00000238984(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0034593"(phosphatidylinositol bisphosphate phosphatase activity)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR002013(Synaptojanin, N-terminal)|reactome:R-MMU-1483248|reactome:R-MMU-1660514|refseq:NP_109617.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:uNMFaNXMhHRq0qrL5+lVqz1Uel810090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q8CAS9 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908568|uniprotkb:Q6IRT6|uniprotkb:Q99LF9 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:parp9_mouse(display_long)|uniprotkb:Parp9(gene name)|psi-mi:Parp9(display_short)|uniprotkb:Bal(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 9(gene name synonym)|uniprotkb:B aggressive lymphoma protein homolog(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 9(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|refseq:XP_006522818.1|refseq:XP_006522819.1|refseq:XP_006522820.1|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:0060330"(regulation of response to interferon-gamma)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0072570"(ADP-D-ribose binding)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|reactome:R-MMU-197264|refseq:NP_084529.1|interpro:IPR002589(Appr-1-p processing)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR043472|mint:Q8CAS9 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:EchtEAWs2DyKqeqvXvPkq5wKRYQ10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:E9PZJ8 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908800|ensembl:ENSMUSP00000036726|uniprotkb:Q6PB36|uniprotkb:Q8C1G1|uniprotkb:Q8C707|uniprotkb:Q8K292 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:ascc3_mouse(display_long)|uniprotkb:Ascc3(gene name)|psi-mi:Ascc3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000038774(gene)|ensembl:ENSMUST00000035606(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:E9PZJ8|refseq:NP_932124.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:3I/JnJBenvV+YpjqxIwbfPEK9WA10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:L7N451 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6907889|ensembl:ENSMUSP00000006667|ensembl:ENSMUSP00000138950 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:l7n451_mouse(display_long)|uniprotkb:Gvin1(gene name)|psi-mi:Gvin1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:XP_017167845.1|ensembl:ENSMUSG00000045868(gene)|ensembl:ENSMUST00000006667(transcript)|ensembl:ENSMUST00000183409(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR027417|interpro:IPR029028|interpro:IPR030383|refseq:NP_001034249.2|refseq:NP_083276.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:5ER/IdaBI4VYG+spa42LKQ2hTMM10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q6P5D8 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6907867|ensembl:ENSMUSP00000121835|uniprotkb:Q6PDM8|uniprotkb:Q6PE93|uniprotkb:Q6ZQ78|uniprotkb:Q811H3|uniprotkb:Q8BP09|uniprotkb:Q9D4M7 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:smhd1_mouse(display_long)|uniprotkb:Smchd1(gene name)|psi-mi:Smchd1(display_short)|uniprotkb:Kiaa0650(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000024054(gene)|ensembl:ENSMUST00000127430(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:Q6P5D8|rcsb pdb:6N64|refseq:NP_083163.3 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:hpvZulbZ6q3A01pCveP/AZKq2LU10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q6ZQ58 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908968|ensembl:ENSMUSP00000136673|intact:EBI-9030511|uniprotkb:A2AFQ8|uniprotkb:J3QNB1|uniprotkb:Q7TSF7 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:larp1_mouse(display_long)|uniprotkb:Larp1(gene name)|psi-mi:Larp1(display_short)|uniprotkb:Kiaa0731(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:Larp(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000037331(gene)|ensembl:ENSMUST00000178636(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008494"(translation activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|refseq:NP_082727.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:DgxWWF7aiKBOUyGXmibtu8Wh+DU10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q924C1 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6907785|ensembl:ENSMUSP00000084257|uniprotkb:A2RRJ5|uniprotkb:Q7TMP2|uniprotkb:Q80TF9|uniprotkb:Q9CRI9|uniprotkb:Q9CT48 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:xpo5_mouse(display_long)|uniprotkb:Xpo5(gene name)|psi-mi:Xpo5(display_short)|uniprotkb:Kiaa1291(gene name synonym)|uniprotkb:Ranbp21(gene name synonym)|uniprotkb:Ran-binding protein 21(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000067150(gene)|ensembl:ENSMUST00000087031(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016442"(RISC complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:1900370"(positive regulation of RNA interference)|go:"GO:1905172"(RISC complex binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040018|mint:Q924C1|refseq:NP_082474.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:npbBFtlUZCx9pnmtdFLQ4qODLzU10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9D071 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-4283533|uniprotkb:Q925N8|uniprotkb:Q9CWX3|uniprotkb:F8WHX3|ensembl:ENSMUSP00000130900 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:mms19_mouse(display_long)|uniprotkb:Mms19(gene name)|psi-mi:Mms19(display_short)|uniprotkb:Mms19l(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_082428.1|ensembl:ENSMUSG00000025159(gene)|ensembl:ENSMUST00000171561(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|rcsb pdb:6TBL|rcsb pdb:6TC0 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:S24j+ddJAniA1XEtuEoZvrT6K7s10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q8K1R3 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6907693|ensembl:ENSMUSP00000020756|uniprotkb:Q3UEP9|uniprotkb:Q810U7|uniprotkb:Q812B3|uniprotkb:Q8R2U3|uniprotkb:Q9DC52 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:pnpt1_mouse(display_long)|uniprotkb:Pnpt1(gene name)|psi-mi:Pnpt1(display_short)|uniprotkb:Pnpase(gene name synonym)|uniprotkb:3'-5' RNA exonuclease OLD35(gene name synonym)|uniprotkb:PNPase old-35(gene name synonym)|uniprotkb:Polynucleotide phosphorylase 1(gene name synonym)|uniprotkb:Polynucleotide phosphorylase-like protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:XP_011242053.1|ensembl:ENSMUSG00000020464(gene)|ensembl:ENSMUST00000020756(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000957"(mitochondrial RNA catabolic process)|go:"GO:0000958"(mitochondrial mRNA catabolic process)|go:"GO:0000962"(positive regulation of mitochondrial RNA catabolic process)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0000965"(mitochondrial RNA 3'-end processing)|go:"GO:0004654"(polyribonucleotide nucleotidyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0034046"("poly(G) binding")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035927"(RNA import into mitochondrion)|go:"GO:0035928"(rRNA import into mitochondrion)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0045025"(mitochondrial degradosome)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060416"(response to growth hormone)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0097222"(mitochondrial mRNA polyadenylation)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR003029(S1, RNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR020568|interpro:IPR022967|interpro:IPR027408|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612|rcsb pdb:1WHU|go:"GO:0097421"(liver regeneration)|refseq:NP_082145.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:SoydVTg48ULE83TRnyy6mUux/iU10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:B9EJ54 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6907666|ensembl:ENSMUSP00000039656 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:b9ej54_mouse(display_long)|uniprotkb:Nup205(gene name)|psi-mi:Nup205(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000038759(gene)|ensembl:ENSMUST00000043815(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|refseq:NP_081789.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:buyzgJjQhEQQLF0ZIwi42k1yIzc10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q8BKC5 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-643605|uniprotkb:Q3TEG2|uniprotkb:Q7TQC6|uniprotkb:Q9EQ30|ensembl:ENSMUSP00000032898 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:ipo5_mouse(display_long)|uniprotkb:Ranbp5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym)|uniprotkb:Ipo5(gene name)|psi-mi:Ipo5(display_short)|uniprotkb:Kpnb3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_076068.1|refseq:XP_006519603.1|ensembl:ENSMUSG00000030662(gene)|ensembl:ENSMUST00000032898(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:Q8BKC5|go:"GO:0006607"(NLS-bearing protein import into nucleus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:ZtMfEhsr1lfJDBglaNlc7j4GHZ010090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9D8C4 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908025|ensembl:ENSMUSP00000010502|uniprotkb:Q3V2E7 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:in35_mouse(display_long)|uniprotkb:Ifi35(gene name)|psi-mi:Ifi35(display_short)|uniprotkb:Ifp35(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000010358(gene)|ensembl:ENSMUST00000010502(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034460|mint:Q9D8C4|refseq:NP_081596.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:690pLYDHOyQAO0FnFRfO6+La2UA10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:B2RQC6 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-3043834|ensembl:ENSMUSP00000013773|uniprotkb:B7ZN27 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:pyr1_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000013629(gene)|ensembl:ENSMUST00000013773(transcript)|go:"GO:0002134"(UTP binding)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016597"(amino acid binding)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0001889"(liver development)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|go:"GO:0019899"(enzyme binding)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:B2RQC6|reactome:R-MMU-500753|refseq:NP_076014.1|refseq:NP_001276451.1|dip:DIP-61412N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:t+qQw7me78vEm/Y4VBBhS8fmCsY10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q3ULL6 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908937|ensembl:ENSMUSP00000075614 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:q3ull6_mouse(display_long)|uniprotkb:Upf3b(gene name)|psi-mi:Upf3b(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000036572(gene)|ensembl:ENSMUST00000076265(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR005120(Nonsense-mediated decay UPF3)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034979|interpro:IPR035979|interpro:IPR039722|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-975957|refseq:NP_080849.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:aiFXMJ9WNcnpfPfoZZmK4Kr+gzg10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:G5E829 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-687987|ensembl:ENSMUSP00000020107 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:at2b1_mouse(display_long)|uniprotkb:Atp2b1(gene name)|psi-mi:Atp2b1(display_short)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_080758.1|refseq:XP_011241851.1|ensembl:ENSMUSG00000019943(gene)|ensembl:ENSMUST00000020107(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009409"(response to cold)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|go:"GO:1901660"(calcium ion export)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990034"(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030320|interpro:IPR036412|interpro:IPR044492|reactome:R-MMU-418359|reactome:R-MMU-5578775|reactome:R-MMU-936837 - - comment:ATPase, Ca++ transporting, plasma membrane 1|comment:"AfCS Y2H protein 53735. Sequence retrieved from cross-reference Protein GI: 28500402"|comment:"similar to AT2B1_PIG Plasma membrane calcium-transporting ATPase 1 (99%)."|caution:"[gi:28500402] This record was removed as a result of standard genome annotation processing." figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:xCo2VYA4dyZrc2qUJTS9IbA4TIQ10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9CR67 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908386|ensembl:ENSMUSP00000042852|ensembl:ENSMUSP00000124390|uniprotkb:Q544Q3|uniprotkb:Q9D3M3|uniprotkb:Q9DAV4 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:tmm33_mouse(display_long)|uniprotkb:Tmem33(gene name)|psi-mi:Tmem33(display_short)|uniprotkb:Db83(gene name synonym)|uniprotkb:Protein DB83(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001272381.1|ensembl:ENSMUSG00000037720(gene)|ensembl:ENSMUST00000037918(transcript)|ensembl:ENSMUST00000161369(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061024"(membrane organization)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR005344(Protein of unknown function UPF0121)|refseq:NP_083251.2|refseq:NP_084384.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:V8cQ2U1y2CMwAO/KHdDqGzm+dgU10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q922J9 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908089|ensembl:ENSMUSP00000033018|ensembl:ENSMUSP00000128695|uniprotkb:Q8BZS2|uniprotkb:Q9CXE8|uniprotkb:Q9D0Q1|uniprotkb:Q9DAU2 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:facr1_mouse(display_long)|uniprotkb:Far1(gene name)|psi-mi:Far1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001272760.1|ensembl:ENSMUSG00000030759(gene)|ensembl:ENSMUST00000033018(transcript)|ensembl:ENSMUST00000164745(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0010025"(wax biosynthetic process)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0080019"("fatty-acyl-CoA reductase (alcohol-forming) activity")|go:"GO:0102965"(alcohol-forming fatty acyl-CoA reductase activity)|interpro:IPR013120(Male sterility, NAD-binding)|interpro:IPR026055|interpro:IPR033640|interpro:IPR036291|reactome:R-MMU-9640463|refseq:XP_006508190.1|refseq:XP_006508191.1|refseq:XP_006508192.1|refseq:XP_006508193.1|refseq:XP_006508194.1|refseq:NP_081655.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:vF/A50qFkhMKkSt6OlEeSLLkktw10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q68FD5 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-769168|ensembl:ENSMUSP00000099475 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:clh1_mouse(display_long)|uniprotkb:Cltc(gene name)|psi-mi:Cltc(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001003908.1|dip:DIP-31947N|ensembl:ENSMUSG00000047126(gene)|ensembl:ENSMUST00000103186(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042277"(peptide binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q68FD5|rcsb pdb:5ODS|reactome:R-MMU-177504|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0032051"(clathrin light chain binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:iHg/TOG2rWePqtsEmuc/szn/chI10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9EPK7 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908541|ensembl:ENSMUSP00000022696|uniprotkb:Q3TP94|uniprotkb:Q80TS9|uniprotkb:Q8BSK5|uniprotkb:Q8C9M7|uniprotkb:Q8CB42|uniprotkb:Q8CBL8|uniprotkb:Q8CEF5 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:xpo7_mouse(display_long)|uniprotkb:Xpo7(gene name)|psi-mi:Xpo7(display_short)|uniprotkb:Kiaa0745(gene name synonym)|uniprotkb:Ranbp16(gene name synonym)|uniprotkb:Ran-binding protein 16(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000022100(gene)|ensembl:ENSMUST00000022696(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040021|interpro:IPR044189|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|refseq:NP_075532.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:A5RLgPchGVYM5H0u27jyOFODf/g10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:O35309 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6910367|ensembl:ENSMUSP00000028314|ensembl:ENSMUSP00000108325|ensembl:ENSMUSP00000120647|uniprotkb:Q99M49 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:nmi_mouse(display_long)|uniprotkb:Nmi(gene name)|psi-mi:Nmi(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:XP_006498281.1|ensembl:ENSMUSG00000026946(gene)|ensembl:ENSMUST00000028314(transcript)|ensembl:ENSMUST00000112705(transcript)|ensembl:ENSMUST00000145481(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|refseq:NP_001135420.1|refseq:NP_001135421.1|refseq:NP_062274.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:9X5RUlhyAOGncBgay3QZBo+ga+w10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:G5E8N7 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908891|ensembl:ENSMUSP00000003044|ensembl:ENSMUSP00000103508 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:g5e8n7_mouse(display_long)|uniprotkb:Pnkp(gene name)|psi-mi:Pnkp(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001277693.1|ensembl:ENSMUSG00000002963(gene)|ensembl:ENSMUST00000003044(transcript)|ensembl:ENSMUST00000107876(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0046403"(polynucleotide 3'-phosphatase activity)|go:"GO:0046404"(polydeoxyribonucleotide 5'-hydroxyl-kinase activity)|go:"GO:0046939"(nucleotide phosphorylation)|go:"GO:0051103"(DNA ligation involved in DNA repair)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR006549(HAD-superfamily hydrolase, subfamily IIIA)|interpro:IPR006550(Polynucleotide kinase 3-phosphatase)|interpro:IPR006551(DNA 3-phosphatase)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013954(Polynucleotide kinase 3 phosphatase, central region)|interpro:IPR023214|interpro:IPR027417|interpro:IPR036412|interpro:IPR041388|refseq:NP_067524.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:l5U7V1yBDzuMsuSUSYlcpK1q8Ak10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:O89079 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908653|ensembl:ENSMUSP00000071078|uniprotkb:Q9JM65 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:cope_mouse(display_long)|uniprotkb:Cope(gene name)|psi-mi:Cope(display_short)|uniprotkb:Cope1(gene name synonym)|uniprotkb:Epsilon-coat protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000055681(gene)|ensembl:ENSMUST00000066469(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5A1V|rcsb pdb:5A1Y|rcsb pdb:5NZT|rcsb pdb:5NZV|reactome:R-MMU-6807878|reactome:R-MMU-6811434|refseq:NP_067513.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:3/JW7Qbp7/1XvfJFBRhfPiW0TN810090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9ESJ0 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6122886|uniprotkb:E9QLH3|uniprotkb:Q6ZPJ4|ensembl:ENSMUSP00000086909 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:xpo4_mouse(display_long)|uniprotkb:Xpo4(gene name)|psi-mi:Xpo4(display_short)|uniprotkb:Kiaa1721(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_065252.1|ensembl:ENSMUSG00000021952(gene)|ensembl:ENSMUST00000089482(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|rcsb pdb:5DLQ - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:E81V4/gVadqPD5hvLHeFnEbavkc10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9JLI8 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908246|ensembl:ENSMUSP00000019118|uniprotkb:Q6ZQI2|uniprotkb:Q8BPK9|uniprotkb:Q8C3B7|uniprotkb:Q8CFU9 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:sart3_mouse(display_long)|uniprotkb:Sart3(gene name)|psi-mi:Sart3(display_short)|uniprotkb:Kiaa0156(gene name synonym)|uniprotkb:Tumor-rejection antigen SART3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000018974(gene)|ensembl:ENSMUST00000019118(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005691"(U6atac snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030624"(U6atac snRNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0061574"(ASAP complex)|go:"GO:0071001"(U4/U6 snRNP)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903586"(positive regulation of histone deubiquitination)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008669(Lsm interaction)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034217|interpro:IPR034218|interpro:IPR035979|refseq:NP_058622.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:8sHlrSQvdRLEdh54zyFG1fA4P8410090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:P61620 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908047|ensembl:ENSMUSP00000032168|uniprotkb:P38378|uniprotkb:P57726|uniprotkb:Q3TXA5 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:s61a1_mouse(display_long)|uniprotkb:Sec61a1(gene name)|psi-mi:Sec61a1(display_short)|uniprotkb:Sec61a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000030082(gene)|ensembl:ENSMUST00000032168(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0039019"(pronephric nephron development)|go:"GO:0043022"(ribosome binding)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|refseq:NP_058602.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:C+EzS02H/FYMX2nyfksXpRMs8G010090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9Z1D1 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-642408|uniprotkb:Q9R079|ensembl:ENSMUSP00000004206 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:eif3g_mouse(display_long)|uniprotkb:Eif3s4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym)|uniprotkb:Eif3g(gene name)|psi-mi:Eif3g(display_short)|uniprotkb:Eif3p42(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_058572.2|ensembl:ENSMUSG00000070319(gene)|ensembl:ENSMUST00000004206(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:Q9Z1D1|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:Tg6eCPZZkVgKsOicPmasuzr8gYs10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q922D4 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-4286373|uniprotkb:Q6ZPM9|uniprotkb:Q8BTW6|uniprotkb:Q9D2X9|ensembl:ENSMUSP00000025846 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:pp6r3_mouse(display_long)|uniprotkb:Ppp6r3(gene name)|psi-mi:Ppp6r3(display_short)|uniprotkb:D19Ertd703e(gene name synonym)|uniprotkb:Kiaa1558(gene name synonym)|uniprotkb:Pp6r3(gene name synonym)|uniprotkb:Saps3(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001157631.1|refseq:NP_083275.1|refseq:NP_083732.1|ensembl:ENSMUSG00000024908(gene)|ensembl:ENSMUST00000025846(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q922D4|reactome:R-MMU-171319|reactome:R-MMU-204005|refseq:XP_006531859.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:cfyYAB9Ybqu8fRU64DNvVMI6zOE10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9CQM9 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-4319195|uniprotkb:Q5I0V8|uniprotkb:Q9JLZ2|ensembl:ENSMUSP00000066621 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:glrx3_mouse(display_long)|uniprotkb:Glrx3(gene name)|psi-mi:Glrx3(display_short)|uniprotkb:Picot(gene name synonym)|uniprotkb:Txnl2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:Thioredoxin-like protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_075629.2|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:Q9CQM9|rcsb pdb:1WIK|ensembl:ENSMUSG00000031068(gene)|ensembl:ENSMUST00000064404(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:fgDgQ7pzk+HxZeHtXPTSCf5FShM10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9JKF1 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-644633|ensembl:ENSMUSP00000128278|uniprotkb:G3UW45 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:iqga1_mouse(display_long)|uniprotkb:Iqgap1(gene name)|psi-mi:Iqgap1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|ensembl:ENSMUSG00000030536(gene)|ensembl:ENSMUST00000167377(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010761"(fibroblast migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0031252"(cell leading edge)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:Q9JKF1|reactome:R-MMU-373753|reactome:R-MMU-5626467|reactome:R-MMU-5674135|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013106|reactome:R-MMU-9013148|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-MMU-9013149|refseq:NP_057930.2|reactome:R-MMU-9013404|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:qjWT+er4GkLOlebk3zzRHh2Iqoo10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q60931 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-771123|uniprotkb:Q8BNG2|ensembl:ENSMUSP00000009036 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:vdac3_mouse(display_long)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym)|uniprotkb:Vdac3(gene name)|psi-mi:Vdac3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_035826.1|ensembl:ENSMUSG00000008892(gene)|ensembl:ENSMUST00000009036(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0016020"(membrane)|go:"GO:0046930"(pore complex)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030271|mint:Q60931|reactome:R-MMU-5689880 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:cBs9pPTPorGZoBuaaQDE1ZEoWGQ10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q60930 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-444578|ensembl:ENSMUSP00000022293|uniprotkb:Q78MH6|uniprotkb:Q99L98 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:vdac2_mouse(display_long)|uniprotkb:Voltage-dependent anion-selective channel protein 6(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)|uniprotkb:Vdac2(gene name)|psi-mi:Vdac2(display_short)|uniprotkb:Vdac6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_035825.1|ensembl:ENSMUSG00000021771(gene)|ensembl:ENSMUST00000022293(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:Q60930|reactome:R-MMU-5689880 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:ApSD4TVlagQ1QHePbOZw7J5rmzQ10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9Z1Q9 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6123642|uniprotkb:Q9QUN2|ensembl:ENSMUSP00000084572 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:syvc_mouse(display_long)|uniprotkb:Vars1(gene name)|psi-mi:Vars1(display_short)|uniprotkb:Bat6(gene name synonym)|uniprotkb:G7a(gene name synonym)|uniprotkb:Protein G7a(gene name synonym)|uniprotkb:Valyl-tRNA synthetase(gene name synonym)|uniprotkb:Vars(gene name synonym)|uniprotkb:Vars2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_035820.3|refseq:XP_017172884.1|ensembl:ENSMUSG00000007029(gene)|ensembl:ENSMUST00000087315(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004832"(valine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006438"(valyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033705|interpro:IPR036282|interpro:IPR037118|mint:Q9Z1Q9 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:gAbY8qZ5vHpLxCj9zbBarjEd1hk10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q62351 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-3869520|uniprotkb:Q61560|ensembl:ENSMUSP00000023486 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:tfr1_mouse(display_long)|uniprotkb:Tfrc(gene name)|psi-mi:Tfrc(display_short)|uniprotkb:Trfr(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_035768.1|refseq:XP_006522062.1|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:Q62351|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-917977|reactome:R-MMU-9696270|reactome:R-MMU-9696273|ensembl:ENSMUSG00000022797(gene)|ensembl:ENSMUST00000023486(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:VFnVdK5loK3683nCBW7vxIe7M6Y10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q01320 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-642809|uniprotkb:E9PX08|ensembl:ENSMUSP00000068896 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:top2a_mouse(display_long)|uniprotkb:DNA topoisomerase II, alpha isozyme(gene name synonym)|uniprotkb:Top2a(gene name)|psi-mi:Top2a(display_short)|uniprotkb:Top2(gene name synonym)|uniprotkb:Top-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:XP_006533216.1|refseq:NP_035753.2|interpro:IPR031660|interpro:IPR034157|interpro:IPR036890|mint:Q01320|reactome:R-MMU-4615885|interpro:IPR020568|ensembl:ENSMUSG00000020914(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0006265"(DNA topological change)|go:"GO:0006266"(DNA ligation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009330"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex")|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|ensembl:ENSMUST00000068031(transcript)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045870"(positive regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048511"(rhythmic process)|go:"GO:0051309"(female meiosis chromosome separation)|go:"GO:1905463"(negative regulation of DNA duplex unwinding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR012542(DTHCT)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|go:"GO:0030263"(apoptotic chromosome condensation)|dip:DIP-40621N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:4bT7YxXbxkbqULDvXoFRreoX9Gs10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q64310 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-10729508|ensembl:ENSMUSP00000015011 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:surf4_mouse(display_long)|uniprotkb:Surf4(gene name)|psi-mi:Surf4(display_short)|uniprotkb:Surf-4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_035642.1|ensembl:ENSMUSG00000014867(gene)|ensembl:ENSMUST00000015011(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR002995(Surfeit locus 4)|reactome:R-MMU-6798695|reactome:R-MMU-6811434 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:w2B7fj3E/VumF6fR6B+uRhddTG010090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9Z315 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908457|ensembl:ENSMUSP00000047397|uniprotkb:Q8K155|uniprotkb:Q9R1I9|uniprotkb:Q9R270 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:snut1_mouse(display_long)|uniprotkb:Sart1(gene name)|psi-mi:Sart1(display_short)|uniprotkb:Haf(gene name synonym)|uniprotkb:Hypoxia-associated factor(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen recognized by T-cells 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000039148(gene)|ensembl:ENSMUST00000044207(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000481"(maturation of 5S rRNA)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR005011(SART-1 protein)|mint:Q9Z315|reactome:R-MMU-72163|refseq:NP_058578.3 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:xXixsXxmATBD8YAV3KQHjXvKDzo10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:P07091 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-1544173|uniprotkb:P20066|ensembl:ENSMUSP00000001046 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:s10a4_mouse(display_long)|uniprotkb:S100a4(gene name)|psi-mi:S100a4(display_short)|uniprotkb:Capl(gene name synonym)|uniprotkb:Mts1(gene name synonym)|uniprotkb:S100 calcium-binding protein A4(gene name synonym)|uniprotkb:Metastasin(gene name synonym)|uniprotkb:Protein Mts1(gene name synonym)|uniprotkb:Metastatic cell protein(gene name synonym)|uniprotkb:Placental calcium-binding protein(gene name synonym)|uniprotkb:Protein 18A2(gene name synonym)|uniprotkb:PEL98(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:XP_006501240.1|refseq:XP_006501241.1|refseq:NP_035441.1|ensembl:ENSMUSG00000001020(gene)|ensembl:ENSMUST00000001046(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028496|interpro:IPR034325|mint:P07091 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:Y4arEBN4mdaKlTW1rGDx3jQOb6A10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q9EPU0 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6876715|ensembl:ENSMUSP00000075089|uniprotkb:Q3UG00|uniprotkb:Q6GYP5|uniprotkb:Q6PHQ5|uniprotkb:Q8K0N4|uniprotkb:Q99PR4 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:rent1_mouse(display_long)|uniprotkb:Upf1(gene name)|psi-mi:Upf1(display_short)|uniprotkb:Rent1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000058301(gene)|ensembl:ENSMUST00000075666(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q9EPU0|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0042162"(telomeric DNA binding)|refseq:XP_006509667.1|refseq:XP_006509668.1|refseq:NP_001116301.1|refseq:NP_109605.2|dip:DIP-60114N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:rwd4XXdf5Uqjtgao/zILckKP8AM10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:P55096 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-81160|ensembl:ENSMUSP00000029770 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:abcd3_mouse(display_long)|uniprotkb:Abcd3(gene name)|psi-mi:Abcd3(display_short)|uniprotkb:Pmp70(gene name synonym)|uniprotkb:Pxmp1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym)|uniprotkb:68 kDa peroxisomal membrane protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000028127(gene)|ensembl:ENSMUST00000029770(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_033017.2|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|reactome:R-MMU-1369062|reactome:R-MMU-8980692|reactome:R-MMU-9013106|reactome:R-MMU-9603798 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:Y2ShY45j3eR8EFHN89+gfNBOOTw10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:P12382 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-400474|uniprotkb:Q8VDX7|ensembl:ENSMUSP00000020522 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:pfkal_mouse(display_long)|uniprotkb:Pfkl(gene name)|psi-mi:Pfkl(display_short)|uniprotkb:Pfk-l(gene name synonym)|uniprotkb:Pfkb(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme B(gene name synonym)|uniprotkb:6-phosphofructokinase type B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_032852.2|ensembl:ENSMUSG00000020277(gene)|ensembl:ENSMUST00000020522(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:0070095"(fructose-6-phosphate binding)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P12382|reactome:R-MMU-6798695|reactome:R-MMU-70171 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:WlBnp+GuMEVU1PRrdVHwJxZi5gE10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:P27546 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-2526714|uniprotkb:Q05BJ2|uniprotkb:Q3UIS2|uniprotkb:Q3UUH5|uniprotkb:Q3UY36|uniprotkb:Q7TPC6|uniprotkb:Q7TPD4|uniprotkb:Q80YQ5|uniprotkb:Q8CFP5|ensembl:ENSMUSP00000035055 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:map4_mouse(display_long)|uniprotkb:Map4(gene name)|psi-mi:Map4(display_short)|uniprotkb:Mtap4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001192259.1|refseq:NP_001192261.1|refseq:NP_032659.2|ensembl:ENSMUSG00000032479(gene)|ensembl:ENSMUST00000035055(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|mint:P27546|go:"GO:0043005"(neuron projection)|refseq:NP_001298092.1|refseq:NP_001298093.1|refseq:XP_017168653.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:DVblnhNfUaxX6rpvxn660Pq09L410090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:P97310 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-457049|uniprotkb:O08971|uniprotkb:O89057|uniprotkb:Q8C2R0|ensembl:ENSMUSP00000061923 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:mcm2_mouse(display_long)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:Bm28(gene name synonym)|uniprotkb:Cdcl1(gene name synonym)|uniprotkb:Kiaa0030(gene name synonym)|uniprotkb:Mcmd2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_032590.2|dip:DIP-33057N|ensembl:ENSMUSG00000002870(gene)|ensembl:ENSMUST00000058011(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P97310|reactome:R-MMU-176187|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|reactome:R-MMU-69052 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:HwAzfjnxpS94H12oI3OiiHTsEm410090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q80ZH7 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6907970|ensembl:ENSMUSP00000090525|ensembl:ENSMUSP00000133805 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:q80zh7_mouse(display_long)|uniprotkb:Lig3(gene name)|psi-mi:Lig3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001278174.1|refseq:NP_001278175.1|refseq:NP_001278176.1|ensembl:ENSMUSG00000020697(gene)|ensembl:ENSMUST00000092849(transcript)|ensembl:ENSMUST00000173722(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR031916|interpro:IPR036420|interpro:IPR036599|interpro:IPR036957|refseq:XP_006532413.1|refseq:NP_034846.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:NKBRjF9UuMVOyezvfD1ajVjce3M10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q6P9P6 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908345|ensembl:ENSMUSP00000012587|uniprotkb:Q9Z1J0 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:kif11_mouse(display_long)|uniprotkb:Kif11(gene name)|psi-mi:Kif11(display_short)|uniprotkb:Kinesin-related motor protein Eg5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000012443(gene)|ensembl:ENSMUST00000012587(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007051"(spindle organization)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR025901|interpro:IPR027417|interpro:IPR036961|reactome:R-MMU-2132295|reactome:R-MMU-6811434|reactome:R-MMU-983189|refseq:NP_034745.1|dip:DIP-62086N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:UezMxfmkap8jUT2qwT32hICvI/E10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q61699 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-772450|uniprotkb:Q3TNS2|uniprotkb:Q3UIY8|uniprotkb:Q62578|uniprotkb:Q62579|uniprotkb:Q6A0A5|uniprotkb:Q8C430|uniprotkb:Q8VCW6|ensembl:ENSMUSP00000144413|ensembl:ENSMUSP00000144654 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:hs105_mouse(display_long)|uniprotkb:Heat shock-related 100 kDa protein E7I(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:42 degrees C-HSP(gene name synonym)|uniprotkb:Hsph1(gene name)|psi-mi:Hsph1(display_short)|uniprotkb:Hsp105(gene name synonym)|uniprotkb:Hsp110(gene name synonym)|uniprotkb:Kiaa0201(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_038587.2|refseq:NP_001334463.1|dip:DIP-32354N|ensembl:ENSMUSG00000029657(gene)|ensembl:ENSMUST00000201452(transcript)|ensembl:ENSMUST00000202361(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q61699|reactome:R-MMU-3371453 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:pZByRgd8f5XdmB138rYxEMrwkRY10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q31125 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-644519|uniprotkb:Q3TVU6|uniprotkb:Q9Z1W1|ensembl:ENSMUSP00000025186|ensembl:ENSMUSP00000130102 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:s39a7_mouse(display_long)|uniprotkb:Solute carrier family 39 member 7(gene name synonym)|uniprotkb:Histidine-rich membrane protein Ke4(gene name synonym)|uniprotkb:Slc39a7(gene name)|psi-mi:Slc39a7(display_short)|uniprotkb:H2-Ke4(gene name synonym)|uniprotkb:Hke4(gene name synonym)|uniprotkb:Zrt-, Irt-like protein 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001071177.1|refseq:NP_032228.2|ensembl:ENSMUSG00000024327(gene)|ensembl:ENSMUST00000025186(transcript)|ensembl:ENSMUST00000169397(transcript)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR003689(Zinc/iron permease)|reactome:R-MMU-442380 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:BVLmJQnAanBeKDcJBsaDieohUTk10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:P13864 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-301927|uniprotkb:Q80ZU3|uniprotkb:Q9CSC6|uniprotkb:P97413|uniprotkb:Q9QXX6|ensembl:ENSMUSP00000004202 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:dnmt1_mouse(display_long)|uniprotkb:Dnmt1(gene name)|psi-mi:Dnmt1(display_short)|uniprotkb:Dnmt(gene name synonym)|uniprotkb:Met1(gene name synonym)|uniprotkb:Uim(gene name synonym)|uniprotkb:MCMT(gene name synonym)|uniprotkb:DNA methyltransferase MmuI(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001186360.2|refseq:NP_001186361.1|refseq:NP_001186362.1|refseq:NP_034196.5|interpro:IPR031303|interpro:IPR043151|mint:P13864|rcsb pdb:3AV4|rcsb pdb:3AV5|rcsb pdb:3AV6|rcsb pdb:3PT6|rcsb pdb:3PT9|rcsb pdb:4DA4|rcsb pdb:5GUT|rcsb pdb:5GUV|rcsb pdb:5WY1|rcsb pdb:6W8V|rcsb pdb:6W8W|reactome:R-MMU-212300|reactome:R-MMU-4655427|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR010506(DMAP1-binding)|interpro:IPR017198("DNA (cytosine-5)-methyltransferase 1")|interpro:IPR018117|interpro:IPR022702|interpro:IPR029063|ensembl:ENSMUST00000004202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032776"(DNA methylation on cytosine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0044026"(DNA hypermethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051718"("DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates")|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905931"(negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|go:"GO:0016458"(obsolete gene silencing)|ensembl:ENSMUSG00000004099(gene)|refseq:NP_001300940.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:JgHTnDhDn4nuU6ww3jXfDPq01xY10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:O54734 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-773157|uniprotkb:Q8C4P7|ensembl:ENSMUSP00000030538 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:ost48_mouse(display_long)|uniprotkb:Ddost(gene name)|psi-mi:Ddost(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_031864.2|ensembl:ENSMUSG00000028757(gene)|ensembl:ENSMUST00000030538(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034097"(response to cytokine)|go:"GO:0042110"(T cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:O54734|reactome:R-MMU-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:tXotz8rJCykp2nspz37gYrmrBGo10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:O35129 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-445002|uniprotkb:O89075|uniprotkb:Q61336|ensembl:ENSMUSP00000004375 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:phb2_mouse(display_long)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:Bap(gene name synonym)|uniprotkb:Bcap37(gene name synonym)|uniprotkb:Rea(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_031557.2|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098800"(inner mitochondrial membrane protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:O35129|reactome:R-MMU-8949664|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|ensembl:ENSMUSG00000004264(gene)|ensembl:ENSMUST00000004375(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016363"(nuclear matrix)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0016477"(cell migration) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:h4pib54mBeQgOKCe/hib58LM26w10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:O55143 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-770763|uniprotkb:Q9R2A9|uniprotkb:Q9WUT5|ensembl:ENSMUSP00000031423|ensembl:ENSMUSP00000135935 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:at2a2_mouse(display_long)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)|uniprotkb:Atp2a2(gene name)|psi-mi:Atp2a2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_001103610.1|refseq:NP_033852.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0006996"(organelle organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:O55143|reactome:R-MMU-418359|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000029467(gene)|ensembl:ENSMUST00000031423(transcript)|ensembl:ENSMUST00000179939(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:LJG8hpHG2pO9ePikEKYbhsuCeRI10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:P14094 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-770851|ensembl:ENSMUSP00000027863 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q8VDN2 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:P14869 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-529949|uniprotkb:Q99L54|ensembl:ENSMUSP00000083705 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:rla0_mouse(display_long)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Rplp0(gene name)|psi-mi:Rplp0(display_short)|uniprotkb:Arbp(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) refseq:NP_031501.1|ensembl:ENSMUSG00000067274(gene)|ensembl:ENSMUST00000086519(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042277"(peptide binding)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P14869|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:WHl41TZwjtqRSeIExT3vyjrZsJs10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q921K2 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6261012|ensembl:ENSMUSP00000027777 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:q921k2_mouse(display_long)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUST00000027777(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006915"(apoptotic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:Q921K2|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|ensembl:ENSMUSG00000026496(gene)|refseq:NP_031441.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:LeuW0EFJDL/7bR1fRoDZvwA2g/A10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q61102 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6907927|ensembl:ENSMUSP00000033695|uniprotkb:A2AC46|uniprotkb:Q3U7S8 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:abcb7_mouse(display_long)|uniprotkb:Abcb7(gene name)|psi-mi:Abcb7(display_short)|uniprotkb:Abc7(gene name synonym)|uniprotkb:ATP-binding cassette transporter 7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 7, mitochondrial(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) interpro:IPR036640|interpro:IPR039421|mint:Q61102|reactome:R-MMU-1369007|ensembl:ENSMUSG00000031333(gene)|ensembl:ENSMUST00000033695(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140466"(iron-sulfur cluster export from the mitochondrion)|go:"GO:0140481"(ABC-type iron-sulfur cluster transporter activity)|go:"GO:1903331"(positive regulation of iron-sulfur cluster assembly)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|go:"GO:0005743"(mitochondrial inner membrane)|refseq:NP_033722.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:+27KEQlgfCk6DppRFipTKUUS0wo10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q99PV0 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-2551815|ensembl:ENSMUSP00000018449|ensembl:ENSMUSP00000099568|uniprotkb:A5D6Q4|uniprotkb:Q7TQK2|uniprotkb:Q8BRZ5|uniprotkb:Q8K001|uniprotkb:Q5ND30|uniprotkb:Q5ND31 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:prp8_mouse(display_long)|uniprotkb:Prp8(gene name synonym)|uniprotkb:Splicing factor Prp8(gene name synonym)|uniprotkb:Prpf8(gene name)|psi-mi:Prpf8(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000020850(gene)|ensembl:ENSMUST00000018449(transcript)|ensembl:ENSMUST00000102510(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|mint:Q99PV0|reactome:R-MMU-72163|reactome:R-MMU-72165|interpro:IPR037518|refseq:NP_619600.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:vHccw48piO1PjsNcxDszzscPO8010090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q6PDQ2 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-3043852|ensembl:ENSMUSP00000060054 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:chd4_mouse(display_long)|uniprotkb:Chd4(gene name)|psi-mi:Chd4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000063870(gene)|ensembl:ENSMUST00000056889(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070615"|go:"GO:0072553"(terminal button organization)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q6PDQ2|reactome:R-MMU-3214815|reactome:R-MMU-73762|reactome:R-MMU-8943724|reactome:R-MMU-9031628|reactome:R-MMU-6804758|refseq:NP_666091.1|refseq:NP_001333539.1|dip:DIP-59651N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:1ExHO4XVxVn9siWz99wuNhrnZMg10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q8BWY9 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908951|ensembl:ENSMUSP00000044714|uniprotkb:B2RQ25|uniprotkb:Q69ZH6|uniprotkb:Q7TPZ7 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:cip2a_mouse(display_long)|uniprotkb:Cip2a(gene name)|psi-mi:Cip2a(display_short)|uniprotkb:Cancerous inhibitor of PP2A(gene name synonym)|uniprotkb:Kiaa1524(gene name synonym)|uniprotkb:p90 autoantigen homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000033031(gene)|ensembl:ENSMUST00000048374(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042510|go:"GO:0005886"(plasma membrane)|refseq:NP_766204.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:fCcs+7r2LLDGJ51XfVDMm/MgSwg10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q8BX17 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-2550292|uniprotkb:Q3UPH2|ensembl:ENSMUSP00000036603 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:gemi5_mouse(display_long)|uniprotkb:Gemin5(gene name)|psi-mi:Gemin5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000037275(gene)|ensembl:ENSMUST00000035604(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0016604"(nuclear body)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0032797"(SMN complex)|go:"GO:0034718"(SMN-Gemin2 complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|reactome:R-MMU-191859|refseq:NP_001160141.1|refseq:NP_001160142.1|refseq:NP_001160143.1|refseq:NP_766146.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:a2dQ9yhjRVYev2Iml4Zgj8PQi6s10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q3UIR3 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6909035|ensembl:ENSMUSP00000080601|uniprotkb:Q8BN11 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:dtx3l_mouse(display_long)|uniprotkb:Dtx3l(gene name)|psi-mi:Dtx3l(display_short)|uniprotkb:Bbap(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000049502(gene)|ensembl:ENSMUST00000081933(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|mint:Q3UIR3|reactome:R-MMU-983168|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|refseq:NP_001013389.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:F+HLvEDaqOrLLre0jwEk/xAuO6Y10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3TBT3 uniprotkb:Q6NZL1 intact:EBI-3862093|uniprotkb:A7YGY9|uniprotkb:Q3TAV5|uniprotkb:Q3TYP5|uniprotkb:Q3TZY8|uniprotkb:Q3UJW3|uniprotkb:Q8C227|uniprotkb:Q8C5Q3|uniprotkb:Q8K393|uniprotkb:Q9CZY7|ensembl:ENSMUSP00000111393|ensembl:ENSMUSP00000157408 intact:EBI-6908477|ensembl:ENSMUSP00000131734 psi-mi:sting_mouse(display_long)|uniprotkb:Sting1(gene name)|psi-mi:Sting1(display_short)|uniprotkb:Endoplasmic reticulum interferon stimulator(gene name synonym)|uniprotkb:Eris(gene name synonym)|uniprotkb:Mediator of IRF3 activation(gene name synonym)|uniprotkb:Mita(gene name synonym)|uniprotkb:Mpys(gene name synonym)|uniprotkb:Tmem173(gene name synonym)|uniprotkb:Transmembrane protein 173(gene name synonym) psi-mi:q6nzl1_mouse(display_long)|uniprotkb:Dhx37(gene name)|psi-mi:Dhx37(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-10729637|imex:IM-21243-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001276520.1|refseq:NP_001276521.1|refseq:NP_082537.1|dip:DIP-59959N|ensembl:ENSMUSG00000024349(gene)|ensembl:ENSMUST00000115728(transcript)|ensembl:ENSMUST00000237919(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035438"(cyclic-di-GMP binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0061709"(reticulophagy)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1990701"("integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane")|interpro:IPR029158|interpro:IPR033952|interpro:IPR038623|rcsb pdb:4JC5|rcsb pdb:4KBY|rcsb pdb:4KC0|rcsb pdb:4LOJ|rcsb pdb:4LOK|rcsb pdb:4LOL|rcsb pdb:4YP1|rcsb pdb:6XNN|reactome:R-MMU-1834941|reactome:R-MMU-3134975|reactome:R-MMU-3249367|reactome:R-MMU-3270619|reactome:R-MMU-6798695|go:"GO:0061507"(2',3'-cyclic GMP-AMP binding) ensembl:ENSMUSG00000029480(gene)|ensembl:ENSMUST00000169485(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007420"(brain development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042255"(ribosome assembly)|go:"GO:2000020"(positive regulation of male gonad development)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|rcsb pdb:6O16|reactome:R-MMU-6791226|refseq:NP_976064.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2016/03/16 rogid:n8idTbDnMp6Sw5To/kS19oCCAF010090 rogid:voopQ4dLFYex/pOyhN2J7JOxeJE10090 rigid:TOShrr52/vWMih8he8+orTlhRHw false ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P542 uniprotkb:P30681 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910056|ensembl:ENSMUSP00000065940|uniprotkb:Q3UXT1|uniprotkb:Q9EQD5 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:hmgb2_mouse(display_long)|uniprotkb:Hmgb2(gene name)|psi-mi:Hmgb2(display_short)|uniprotkb:Hmg2(gene name synonym)|uniprotkb:High mobility group protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6910449|imex:IM-21243-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:XP_006509587.1|ensembl:ENSMUSG00000054717(gene)|ensembl:ENSMUST00000067925(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032075"(positive regulation of nuclease activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0044378"(non-sequence-specific DNA binding, bending)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR036910|mint:P30681|reactome:R-MMU-140342|refseq:NP_032278.1|dip:DIP-899N - - - figure legend:Fig. 5B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2014/10/16 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:z+MIQN4YHLlD59sncgaWv7W9+X010090 intact-crc:16F2629E2905C09A|rigid:cqtQAfYV5NSUKsaQJVzA7wJjLn0 false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6P542 uniprotkb:P15092 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-6910116|uniprotkb:Q921V9 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:ifi4_mouse(display_long)|uniprotkb:Ifi204(gene name)|psi-mi:Ifi204(display_short)|uniprotkb:Interferon-inducible protein p204(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6910449|imex:IM-21243-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001047"|go:"GO:0001078"|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0044822"|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048839"(inner ear development)|go:"GO:0043032"(positive regulation of macrophage activation)|refseq:NP_032355.2|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|go:"GO:0005737"(cytoplasm)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0005730"(nucleolus)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0006351"(transcription, DNA-templated) - - - figure legend:Fig. 5B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2014/10/16 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:yK9xND/SFmZgIDZex/cWx58X3/g10090 intact-crc:16F2629E2905C09A|rigid:cqtQAfYV5NSUKsaQJVzA7wJjLn0 false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6P542 uniprotkb:Q9EQU5 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 intact:EBI-1543689|uniprotkb:Q9CY82|uniprotkb:Q9D0A9|uniprotkb:Q9Z181|uniprotkb:A2BE95|ensembl:ENSMUSP00000099930 psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:set_mouse(display_long)|uniprotkb:Set(gene name)|psi-mi:Set(display_short)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6910449|imex:IM-21243-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 refseq:NP_001191804.1|refseq:NP_076360.1|ensembl:ENSMUSG00000054766(gene)|ensembl:ENSMUST00000102866(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9EQU5|reactome:R-MMU-2299718|reactome:R-MMU-450520 - - - figure legend:Fig. 5B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2014/10/16 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 rogid:1PEoqWcGzQ6q4T2SbfswpNI2Dr810090 intact-crc:16F2629E2905C09A|rigid:cqtQAfYV5NSUKsaQJVzA7wJjLn0 false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9EQU5 uniprotkb:Q6P542 intact:EBI-1543689|uniprotkb:Q9CY82|uniprotkb:Q9D0A9|uniprotkb:Q9Z181|uniprotkb:A2BE95|ensembl:ENSMUSP00000099930 intact:EBI-6909754|ensembl:ENSMUSP00000036881|uniprotkb:Q6NV71 psi-mi:set_mouse(display_long)|uniprotkb:Set(gene name)|psi-mi:Set(display_short)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym) psi-mi:abcf1_mouse(display_long)|uniprotkb:Abcf1(gene name)|psi-mi:Abcf1(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Lee et al. (2013) pubmed:23263557|imex:IM-21243 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0974"(InnateDB) intact:EBI-6910465|imex:IM-21243-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191804.1|refseq:NP_076360.1|ensembl:ENSMUSG00000054766(gene)|ensembl:ENSMUST00000102866(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9EQU5|reactome:R-MMU-2299718|reactome:R-MMU-450520 ensembl:ENSMUSG00000038762(gene)|ensembl:ENSMUST00000043757(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006413"(translational initiation)|go:"GO:0008494"(translation activator activity)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|reactome:R-MMU-382556|refseq:NP_038882.1 - - - figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/07/29 2014/10/16 rogid:1PEoqWcGzQ6q4T2SbfswpNI2Dr810090 rogid:cFtcAOnkUKiWKyI5XTjGpxqF6SI10090 intact-crc:68D5588E8A21DFFC|rigid:a52BM9OdjQaWox4a/oMiuiB8juo false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)