#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P14176	uniprotkb:P14175	intact:EBI-8794761|ensemblbacteria:AAC75725|ensemblbacteria:BAA16543	intact:EBI-546797|ensemblbacteria:AAC75724|ensemblbacteria:BAA16542	psi-mi:prow_ecoli(display_long)|uniprotkb:proW(gene name)|psi-mi:proW(display_short)|uniprotkb:b2678(locus name)|uniprotkb:JW2653(locus name)	psi-mi:prov_ecoli(display_long)|uniprotkb:proV(gene name)|psi-mi:proV(display_short)|uniprotkb:b2677(locus name)|uniprotkb:JW2652(locus name)	psi-mi:"MI:0808"(comigration in sds page)	Gul et al. (2013)	pubmed:23249124|imex:IM-21572	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8794820|imex:IM-21572-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC75725(transcript)|ensemblbacteria:b2678(gene)|ensemblbacteria:BAA16543(gene)|ensemblbacteria:BAA16543(transcript)|go:"GO:0005275"(amine transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0015226"(carnitine transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:1902603"(carnitine transmembrane transport)|refseq:WP_000774988.1|interpro:IPR035906|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:NP_417164.1	refseq:NP_417163.1|refseq:WP_000985494.1|ensemblbacteria:AAC75724(transcript)|ensemblbacteria:b2677(gene)|ensemblbacteria:BAA16542(gene)|ensemblbacteria:BAA16542(transcript)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005275"(amine transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005892(Glycine betaine/L-proline transport ATP-binding subunit)|interpro:IPR017871|interpro:IPR027417|dip:DIP-10574N	-	-	-	figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/15	2014/10/16	rogid:bGLgsbuewHAagE+egsg4fZBJ2EE83333	rogid:qkwFi9F/MpKPaDEc5MPFYJ4BN6M83333	intact-crc:07687D0E3FA7D781|rigid:90uHXhPfqEJMwGQmR4pL2qZuw08	false	his tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14175	uniprotkb:P14176	intact:EBI-546797|ensemblbacteria:AAC75724|ensemblbacteria:BAA16542	intact:EBI-8794761|ensemblbacteria:AAC75725|ensemblbacteria:BAA16543	psi-mi:prov_ecoli(display_long)|uniprotkb:proV(gene name)|psi-mi:proV(display_short)|uniprotkb:b2677(locus name)|uniprotkb:JW2652(locus name)	psi-mi:prow_ecoli(display_long)|uniprotkb:proW(gene name)|psi-mi:proW(display_short)|uniprotkb:b2678(locus name)|uniprotkb:JW2653(locus name)	psi-mi:"MI:0808"(comigration in sds page)	Gul et al. (2013)	pubmed:23249124|imex:IM-21572	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8794760|imex:IM-21572-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417163.1|refseq:WP_000985494.1|ensemblbacteria:AAC75724(transcript)|ensemblbacteria:b2677(gene)|ensemblbacteria:BAA16542(gene)|ensemblbacteria:BAA16542(transcript)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005275"(amine transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005892(Glycine betaine/L-proline transport ATP-binding subunit)|interpro:IPR017871|interpro:IPR027417|dip:DIP-10574N	ensemblbacteria:AAC75725(transcript)|ensemblbacteria:b2678(gene)|ensemblbacteria:BAA16543(gene)|ensemblbacteria:BAA16543(transcript)|go:"GO:0005275"(amine transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0015226"(carnitine transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:1902603"(carnitine transmembrane transport)|refseq:WP_000774988.1|interpro:IPR035906|interpro:IPR000515(Binding-protein-dependent transport systems inner membrane component)|refseq:NP_417164.1	-	-	-	figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/15	2014/10/16	rogid:qkwFi9F/MpKPaDEc5MPFYJ4BN6M83333	rogid:bGLgsbuewHAagE+egsg4fZBJ2EE83333	intact-crc:3719E94B5AEBA75C|rigid:QeuCc6Na4NxZEcXkLTo+sMQcIgM	false	-	his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14175	uniprotkb:P0AFM2	intact:EBI-546797|ensemblbacteria:AAC75724|ensemblbacteria:BAA16542	intact:EBI-1129961|uniprotkb:P14177|ensemblbacteria:AAC75726|ensemblbacteria:BAA16544	psi-mi:prov_ecoli(display_long)|uniprotkb:proV(gene name)|psi-mi:proV(display_short)|uniprotkb:b2677(locus name)|uniprotkb:JW2652(locus name)	psi-mi:prox_ecoli(display_long)|uniprotkb:proX(gene name)|psi-mi:proX(display_short)|uniprotkb:proU(gene name synonym)|uniprotkb:b2679(locus name)|uniprotkb:JW2654(locus name)|uniprotkb:GBBP(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Gul et al. (2013)	pubmed:23249124|imex:IM-21572	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8794760|imex:IM-21572-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417163.1|refseq:WP_000985494.1|ensemblbacteria:AAC75724(transcript)|ensemblbacteria:b2677(gene)|ensemblbacteria:BAA16542(gene)|ensemblbacteria:BAA16542(transcript)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005275"(amine transmembrane transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006865"(amino acid transport)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005892(Glycine betaine/L-proline transport ATP-binding subunit)|interpro:IPR017871|interpro:IPR027417|dip:DIP-10574N	refseq:WP_001216525.1|ensemblbacteria:AAC75726(transcript)|ensemblbacteria:b2679(gene)|ensemblbacteria:BAA16544(gene)|ensemblbacteria:BAA16544(transcript)|go:"GO:0006865"(amino acid transport)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:0050997"(quaternary ammonium group binding)|refseq:NP_417165.1|interpro:IPR007210(ABC-type glycine betaine transport system, substrate-binding region)|rcsb pdb:1R9L|rcsb pdb:1R9Q	-	-	-	figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/15	2014/10/16	rogid:qkwFi9F/MpKPaDEc5MPFYJ4BN6M83333	rogid:AJfjaLORWaefRcF3Gn6LNx1Wksc83333	intact-crc:3719E94B5AEBA75C|rigid:QeuCc6Na4NxZEcXkLTo+sMQcIgM	false	-	tag:n-n|his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:17750"	uniprotkb:P0AFM2	intact:EBI-8794837|chebi:"CHEBI:29050"|chebi:"CHEBI:27128"|chebi:"CHEBI:295651"|chebi:"CHEBI:3073"|chebi:"CHEBI:15264"|chebi:"CHEBI:13895"|chebi:"CHEBI:22858"|chebi:"CHEBI:24370"	intact:EBI-1129961|uniprotkb:P14177|ensemblbacteria:AAC75726|ensemblbacteria:BAA16544	psi-mi:glycine betaine(display_short)|psi-mi:"CHEBI:17750"(display_long)|intact:"(trimethylammoniumyl)acetate"(synonym)|intact:1-carboxy-N,N,N-trimethylmethanaminium inner salt(synonym)|intact:2-N,N,N-trimethylammonio acetate(synonym)|intact:abromine(synonym)|intact:acidol(synonym)|intact:Bet(synonym)|intact:betaine(synonym)|intact:Betaine(synonym)|intact:Glycine betaine(synonym)|intact:N,N,N-trimethylammonioacetate(synonym)|intact:Trimethylaminoacetate(synonym)|intact:trimethylglycine(synonym)|intact:trimethylglycocoll(synonym)|intact:"(trimethylammonio)acetate"(iupac name)	psi-mi:prox_ecoli(display_long)|uniprotkb:proX(gene name)|psi-mi:proX(display_short)|uniprotkb:proU(gene name synonym)|uniprotkb:b2679(locus name)|uniprotkb:JW2654(locus name)|uniprotkb:GBBP(gene name synonym)	psi-mi:"MI:0928"(filter trap assay)	Gul et al. (2013)	pubmed:23249124|imex:IM-21572	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-8794828|imex:IM-21572-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:WP_001216525.1|ensemblbacteria:AAC75726(transcript)|ensemblbacteria:b2679(gene)|ensemblbacteria:BAA16544(gene)|ensemblbacteria:BAA16544(transcript)|go:"GO:0006865"(amino acid transport)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031460"(glycine betaine transport)|go:"GO:0043190"("ATP-binding cassette (ABC) transporter complex")|go:"GO:0050997"(quaternary ammonium group binding)|refseq:NP_417165.1|interpro:IPR007210(ABC-type glycine betaine transport system, substrate-binding region)|rcsb pdb:1R9L|rcsb pdb:1R9Q	-	inchi key:KWIUHFFTVRNATP-UHFFFAOYSA-N	-	figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/10/15	2014/10/16	-	rogid:AJfjaLORWaefRcF3Gn6LNx1Wksc83333	intact-crc:1A5D9F9656B8C8A1	false	3h radiolabel:?-?	his tag:c-c|tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)