#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P38316	uniprotkb:Q03818	intact:EBI-2692|uniprotkb:D6VQL3|ensemblfungi:YBR217W	intact:EBI-27344|uniprotkb:D6VZY1|ensemblfungi:YMR159C	psi-mi:atg12_yeast(display_long)|uniprotkb:ATG12(gene name)|psi-mi:ATG12(display_short)|uniprotkb:APG12(gene name synonym)|uniprotkb:YBR217W(locus name)|uniprotkb:YBR1506(orf name)|uniprotkb:Autophagy-related protein 12(gene name synonym)	psi-mi:atg16_yeast(display_long)|uniprotkb:Cytoplasm to vacuole targeting protein 11(gene name synonym)|uniprotkb:SAP18 homolog(gene name synonym)|uniprotkb:YMR159C(locus name)|uniprotkb:YM8520.08C(orf name)|uniprotkb:ATG16(gene name)|psi-mi:ATG16(display_short)|uniprotkb:APG15(gene name synonym)|uniprotkb:APG16(gene name synonym)|uniprotkb:CVT11(gene name synonym)|uniprotkb:SAP18(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Noda et al. (2013)	pubmed:23238393|imex:IM-20884|mint:MINT-8428441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8276552|mint:MINT-8428446|imex:IM-20884-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009776.1|sgd:S000000421|dip:DIP-1189N|reactome:R-SCE-1632852|reactome:R-SCE-8934903|ensemblfungi:YBR217W(gene)|ensemblfungi:YBR217W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|interpro:IPR007242(Autophagy protein 12)|interpro:IPR029071|rcsb pdb:3W1S|mint:MINT-8428448(identity)	refseq:NP_013882.1|sgd:S000004769|dip:DIP-2144N|mint:Q03818|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061908"(phagophore)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905037"(autophagosome organization)|interpro:IPR013923(Autophagy protein 16)|rcsb pdb:2DYM|rcsb pdb:2DYO|rcsb pdb:3A7O|rcsb pdb:3A7P|rcsb pdb:3W1S|ensemblfungi:YMR159C(gene)|ensemblfungi:YMR159C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|mint:MINT-8428449(identity)	-	crc64:74B3C9FD3CEA9265	crc64:6D4308298D4DBB59	comment:mint|figure legend:t1 f1a f1b f1c f2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/09	2014/10/16	rogid:2hGhAejWvm9rPoB9m8JPmjSjFIo559292	rogid:bmw05AxBAI+DZmzlMNmib4F/epw559292	intact-crc:1E827AD57B57FECD|rigid:NmSBOXUlPK76DlUEeqs+9OcYvGU	false	binding-associated region:100-186(MINT-8428465)|his tag:?-?(MINT-8428462)	binding-associated region:1-49(MINT-8428459)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38316	uniprotkb:Q12380	intact:EBI-2692|uniprotkb:D6VQL3|ensemblfungi:YBR217W	intact:EBI-2664|uniprotkb:D6W3M0|ensemblfungi:YPL149W	psi-mi:atg12_yeast(display_long)|uniprotkb:ATG12(gene name)|psi-mi:ATG12(display_short)|uniprotkb:APG12(gene name synonym)|uniprotkb:YBR217W(locus name)|uniprotkb:YBR1506(orf name)|uniprotkb:Autophagy-related protein 12(gene name synonym)	psi-mi:atg5_yeast(display_long)|uniprotkb:ATG5(gene name)|psi-mi:ATG5(display_short)|uniprotkb:APG5(gene name synonym)|uniprotkb:YPL149W(locus name)|uniprotkb:P2601(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Noda et al. (2013)	pubmed:23238393|imex:IM-20884|mint:MINT-8428441	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8276552|mint:MINT-8428446|imex:IM-20884-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009776.1|sgd:S000000421|dip:DIP-1189N|reactome:R-SCE-1632852|reactome:R-SCE-8934903|ensemblfungi:YBR217W(gene)|ensemblfungi:YBR217W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|interpro:IPR007242(Autophagy protein 12)|interpro:IPR029071|rcsb pdb:3W1S|mint:MINT-8428448(identity)	refseq:NP_015176.1|sgd:S000006070|reactome:R-SCE-1632852|dip:DIP-1195N|reactome:R-SCE-8934903|ensemblfungi:YPL149W(gene)|ensemblfungi:YPL149W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061908"(phagophore)|go:"GO:0061912"(selective autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:0140355"(cargo receptor ligand activity)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|rcsb pdb:2DYM|rcsb pdb:2DYO|rcsb pdb:3W1S|mint:MINT-8428450(identity)	-	crc64:74B3C9FD3CEA9265	crc64:BE513A631DEAA0A1	comment:mint|figure legend:t1 f1a f1b f1c f2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/09	2014/10/16	rogid:2hGhAejWvm9rPoB9m8JPmjSjFIo559292	rogid:PMSbzCApcY0S518yzmdDm3bPY74559292	intact-crc:1E827AD57B57FECD|rigid:NmSBOXUlPK76DlUEeqs+9OcYvGU	false	binding-associated region:100-186(MINT-8428465)|his tag:?-?(MINT-8428462)	binding-associated region:1-284(MINT-8428455)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q0WWQ1	uniprotkb:Q9LVK3	intact:EBI-8276607|intact:MINT-8428478|uniprotkb:Q9FKG9|uniprotkb:Q8L982|uniprotkb:Q8S930|ensemblplants:AT5G61500.1	intact:EBI-8276588|intact:MINT-8428480|ensemblplants:AT3G13970.1	psi-mi:atg3_arath(display_long)|uniprotkb:ATG3(gene name)|psi-mi:ATG3(display_short)|uniprotkb:APG3(gene name synonym)|uniprotkb:Autophagy-related E2-like conjugation enzyme ATG3(gene name synonym)|uniprotkb:K11J9.3(orf name)|uniprotkb:At5g61500(locus name)	psi-mi:at12b_arath(display_long)|uniprotkb:ATG12B(gene name)|psi-mi:ATG12B(display_short)|uniprotkb:APG12(gene name synonym)|uniprotkb:APG12B(gene name synonym)|uniprotkb:Autophagy-related protein 12b(gene name synonym)|uniprotkb:MDC16.9(orf name)|uniprotkb:At3g13970(locus name)	psi-mi:"MI:0096"(pull down)	Noda et al. (2013)	pubmed:23238393|imex:IM-20884|mint:MINT-8428441	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8276629|mint:MINT-8428471|imex:IM-20884-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3VX8|refseq:NP_568934.1|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|ensemblplants:AT5G61500(gene)|ensemblplants:AT5G61500.1(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000153"(cytoplasmic ubiquitin ligase complex)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0019776"(Atg8 ligase activity)|go:"GO:0044804"(autophagy of nucleus)|mint:MINT-8428496(identity)	interpro:IPR007242(Autophagy protein 12)|refseq:NP_188013.2|rcsb pdb:1WZ3|interpro:IPR029071|ensemblplants:AT3G13970(gene)|ensemblplants:AT3G13970.1(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0044804"(autophagy of nucleus)|mint:MINT-8428498(identity)	-	comment:mint	comment:mint	figure legend:f2a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/09	2014/10/16	rogid:YcDu1oDKzQBjZZZsnfrpv2D2vAU3702	rogid:yJiDMhG0MiuP273bLx87isVQJVs3702	intact-crc:98E2DF202EF328E9|rigid:JIh/tPgUnpYoJmMGzziBuHiMf2Q	false	glutathione s tranferase tag:?-?(MINT-8428504)	mutation decreasing interaction:57-57(MINT-8428510)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q0WWQ1	uniprotkb:Q9LVK3	intact:EBI-8276607|intact:MINT-8428478|uniprotkb:Q9FKG9|uniprotkb:Q8L982|uniprotkb:Q8S930|ensemblplants:AT5G61500.1	intact:EBI-8276588|intact:MINT-8428480|ensemblplants:AT3G13970.1	psi-mi:atg3_arath(display_long)|uniprotkb:ATG3(gene name)|psi-mi:ATG3(display_short)|uniprotkb:APG3(gene name synonym)|uniprotkb:Autophagy-related E2-like conjugation enzyme ATG3(gene name synonym)|uniprotkb:K11J9.3(orf name)|uniprotkb:At5g61500(locus name)	psi-mi:at12b_arath(display_long)|uniprotkb:ATG12B(gene name)|psi-mi:ATG12B(display_short)|uniprotkb:APG12(gene name synonym)|uniprotkb:APG12B(gene name synonym)|uniprotkb:Autophagy-related protein 12b(gene name synonym)|uniprotkb:MDC16.9(orf name)|uniprotkb:At3g13970(locus name)	psi-mi:"MI:0096"(pull down)	Noda et al. (2013)	pubmed:23238393|imex:IM-20884|mint:MINT-8428441	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8276647|mint:MINT-8428513|imex:IM-20884-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3VX8|refseq:NP_568934.1|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|ensemblplants:AT5G61500(gene)|ensemblplants:AT5G61500.1(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000153"(cytoplasmic ubiquitin ligase complex)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0019776"(Atg8 ligase activity)|go:"GO:0044804"(autophagy of nucleus)|mint:MINT-8428519(identity)	interpro:IPR007242(Autophagy protein 12)|refseq:NP_188013.2|rcsb pdb:1WZ3|interpro:IPR029071|ensemblplants:AT3G13970(gene)|ensemblplants:AT3G13970.1(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0044804"(autophagy of nucleus)|mint:MINT-8428515(identity)	-	comment:mint	comment:mint	figure legend:f2a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/09	2014/10/16	rogid:YcDu1oDKzQBjZZZsnfrpv2D2vAU3702	rogid:yJiDMhG0MiuP273bLx87isVQJVs3702	intact-crc:3BB6E8B01EC49B78|rigid:JIh/tPgUnpYoJmMGzziBuHiMf2Q	false	glutathione s tranferase tag:?-?(MINT-8428520)	mutation decreasing interaction:62-62(MINT-8428516)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)