#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q23972 uniprotkb:Q9VUQ5 intact:EBI-108638|uniprotkb:A4V1P7|uniprotkb:Q9V3T0|uniprotkb:Q9VSS8|uniprotkb:B7Z0F4|uniprotkb:B7Z0F5|ensemblmetazoa:FBpp0076276|ensemblmetazoa:FBpp0076277|ensemblmetazoa:FBpp0076278|ensemblmetazoa:FBpp0288543 intact:EBI-442476|ensemblmetazoa:FBpp0075312|uniprotkb:Q2Q3Y0|uniprotkb:Q2Q3Y1|uniprotkb:Q2Q3Y3|uniprotkb:Q2Q3Y4|uniprotkb:Q2Q3Y5|uniprotkb:Q86P07|uniprotkb:C7LAD2|uniprotkb:Q8T3N2|uniprotkb:Q9VUQ6|intact:EBI-3430439 psi-mi:smg_drome(display_long)|uniprotkb:smg(gene name)|psi-mi:smg(display_short)|uniprotkb:CG5263(orf name) psi-mi:ago2_drome(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:CG7439(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pinder et al. (2013) pubmed:23184089|imex:IM-20885|mint:MINT-8427630 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8173791|mint:MINT-8427635|imex:IM-20885-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137924.1|refseq:NP_001137925.1|refseq:NP_523987.1|refseq:NP_729441.1|refseq:NP_729442.1|flybase:FBgn0016070|ensemblmetazoa:FBgn0016070(gene)|ensemblmetazoa:FBtr0076549(transcript)|ensemblmetazoa:FBtr0076550(transcript)|ensemblmetazoa:FBtr0076551(transcript)|ensemblmetazoa:FBtr0290104(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0017022"(myosin binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030371"(translation repressor activity)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0051236"(establishment of RNA localization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR015327(Smaug, pseudo-HEAT analogous topology)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037093|interpro:IPR037634|mint:Q23972|rcsb pdb:1OXJ|mint:MINT-8427637(identity) ensemblmetazoa:FBgn0087035(gene)|ensemblmetazoa:FBtr0075559(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007279"(pole cell formation)|go:"GO:0007349"(cellularization)|go:"GO:0007367"(segment polarity determination)|go:"GO:0009047"(dosage compensation by hyperactivation of X chromosome)|go:"GO:0009616"(RNAi-mediated antiviral immune response)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0016246"(RNA interference)|go:"GO:0016442"(RISC complex)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0033227"(dsRNA transport)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035190"(syncytial nuclear migration)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9VUQ5|rcsb pdb:1R6Z|rcsb pdb:1T2R|rcsb pdb:1T2S|rcsb pdb:1VYN|rcsb pdb:3MJ0|reactome:R-DME-203927|reactome:R-DME-426486|reactome:R-DME-426496|go:"GO:0035197"(siRNA binding)|refseq:NP_648775.1|refseq:NP_730054.1|flybase:FBgn0087035|dip:DIP-41570N|mint:MINT-8427649(identity) - - - figure legend:f1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2013/04/19 2014/10/16 rogid:MW9LKS8uf5kXs/xlrchusz+UQ+g7227 rogid:Y3Jc/eqc+QUJupZ169PcsPduqro7227 intact-crc:744BC3FD33FDEF6B|rigid:K9qPyBjd4BveypvmoFoctrNZjAg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q23972 uniprotkb:Q32KD4 intact:EBI-108638|uniprotkb:A4V1P7|uniprotkb:Q9V3T0|uniprotkb:Q9VSS8|uniprotkb:B7Z0F4|uniprotkb:B7Z0F5|ensemblmetazoa:FBpp0076276|ensemblmetazoa:FBpp0076277|ensemblmetazoa:FBpp0076278|ensemblmetazoa:FBpp0288543 intact:EBI-105513|ensemblmetazoa:FBpp0086738|ensemblmetazoa:FBpp0086739|ensemblmetazoa:FBpp0294043 psi-mi:smg_drome(display_long)|uniprotkb:smg(gene name)|psi-mi:smg(display_short)|uniprotkb:CG5263(orf name) psi-mi:q32kd4_drome(display_long)|uniprotkb:AGO1(gene name)|psi-mi:AGO1(display_short)|uniprotkb:AGO1-RC(gene name synonym)|uniprotkb:Ago-1(gene name synonym)|uniprotkb:Ago1(gene name synonym)|uniprotkb:Agp1(gene name synonym)|uniprotkb:Dm Ago1(gene name synonym)|uniprotkb:DmAgo1(gene name synonym)|uniprotkb:Dmel\CG6671(gene name synonym)|uniprotkb:MRE20(gene name synonym)|uniprotkb:ago1(gene name synonym)|uniprotkb:ago1-1(gene name synonym)|uniprotkb:anon-WO0257455.29(gene name synonym)|uniprotkb:argonaute1(gene name synonym)|uniprotkb:dAGO1(gene name synonym)|uniprotkb:dAgo1(gene name synonym)|uniprotkb:"l(2)04845"(gene name synonym)|uniprotkb:AGO-1(gene name synonym)|uniprotkb:Ago(gene name synonym)|uniprotkb:"l(2)4845"(gene name synonym)|uniprotkb:"l(2)k00208"(gene name synonym)|uniprotkb:CG6671(orf name)|uniprotkb:Dmel_CG6671(orf name)|uniprotkb:"l(2)k08121"(gene name synonym)|uniprotkb:dmAgo1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Pinder et al. (2013) pubmed:23184089|imex:IM-20885|mint:MINT-8427630 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8173791|mint:MINT-8427635|imex:IM-20885-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137924.1|refseq:NP_001137925.1|refseq:NP_523987.1|refseq:NP_729441.1|refseq:NP_729442.1|flybase:FBgn0016070|ensemblmetazoa:FBgn0016070(gene)|ensemblmetazoa:FBtr0076549(transcript)|ensemblmetazoa:FBtr0076550(transcript)|ensemblmetazoa:FBtr0076551(transcript)|ensemblmetazoa:FBtr0290104(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0017022"(myosin binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030371"(translation repressor activity)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0051236"(establishment of RNA localization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR015327(Smaug, pseudo-HEAT analogous topology)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037093|interpro:IPR037634|mint:Q23972|rcsb pdb:1OXJ|mint:MINT-8427637(identity) refseq:NP_725341.1|refseq:NP_725342.1|flybase:FBgn0262739|refseq:NP_001246314.1|dip:DIP-59685N|ensemblmetazoa:FBgn0262739(gene)|ensemblmetazoa:FBtr0087612(transcript)|ensemblmetazoa:FBtr0087613(transcript)|ensemblmetazoa:FBtr0305592(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007367"(segment polarity determination)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0046959"(habituation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0090328"(regulation of olfactory learning)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q32KD4|rcsb pdb:1R4K|reactome:R-DME-203927|reactome:R-DME-426486|reactome:R-DME-426496|reactome:R-DME-5578749|mint:MINT-8427882(identity) - - - figure legend:f1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2013/04/19 2014/10/16 rogid:MW9LKS8uf5kXs/xlrchusz+UQ+g7227 rogid:YFcWf96n43RSnrWBGXlQpgi4Yvs7227 intact-crc:744BC3FD33FDEF6B|rigid:K9qPyBjd4BveypvmoFoctrNZjAg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)