#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Z1K6 uniprotkb:Q60778 intact:EBI-6861719|ensembl:ENSMUSP00000013338 intact:EBI-644469|uniprotkb:Q564F1|uniprotkb:Q9D6L5|ensembl:ENSMUSP00000032815|ensembl:ENSMUSP00000083012 psi-mi:ari2_mouse(display_long)|uniprotkb:Arih2(gene name)|psi-mi:Arih2(display_short)|uniprotkb:Ari2(gene name synonym)|uniprotkb:Triad1(gene name synonym)|uniprotkb:Uip48(gene name synonym)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:UbcM4-interacting protein 48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym) psi-mi:ikbb_mouse(display_long)|uniprotkb:I-kappa-B-beta(gene name synonym)|uniprotkb:Nfkbib(gene name)|psi-mi:Nfkbib(display_short)|uniprotkb:Ikbb(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lin et al. (2013) imex:IM-20904|pubmed:23179078 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6861746|imex:IM-20904-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000064145(gene)|ensembl:ENSMUST00000013338(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-MMU-983168|refseq:XP_006511788.1|refseq:NP_035920.1 refseq:NP_035038.2|ensembl:ENSMUSG00000030595(gene)|ensembl:ENSMUST00000032815(transcript)|ensembl:ENSMUST00000085851(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q60778|rcsb pdb:1K3Z|rcsb pdb:1OY3|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-445989|reactome:R-MMU-933542|refseq:NP_001293151.1|dip:DIP-37418N go:"GO:0005634"(nucleus) - - figure legend:Fig. 6C|agonist:"MG132 (proteasomal inhibitor), LPS"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-dendritic cell)|taxid:10090(Mouse dendritic cell) - 2013/06/17 2014/10/16 rogid:ow+DsLc6ZINTDmmIFreUsU05k5A10090 rogid:ldopxAYCbS48KB25XbB+cotR8Rk10090 intact-crc:423C0DD6304FFCE0|rigid:lHAB1Eit+jgBNfleANpUFBkR4/E false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60778 uniprotkb:Q9Z1K6 intact:EBI-644469|uniprotkb:Q564F1|uniprotkb:Q9D6L5|ensembl:ENSMUSP00000032815|ensembl:ENSMUSP00000083012 intact:EBI-6861719|ensembl:ENSMUSP00000013338 psi-mi:ikbb_mouse(display_long)|uniprotkb:I-kappa-B-beta(gene name synonym)|uniprotkb:Nfkbib(gene name)|psi-mi:Nfkbib(display_short)|uniprotkb:Ikbb(gene name synonym) psi-mi:ari2_mouse(display_long)|uniprotkb:Arih2(gene name)|psi-mi:Arih2(display_short)|uniprotkb:Ari2(gene name synonym)|uniprotkb:Triad1(gene name synonym)|uniprotkb:Uip48(gene name synonym)|uniprotkb:Triad1 protein(gene name synonym)|uniprotkb:UbcM4-interacting protein 48(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ARIH2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lin et al. (2013) imex:IM-20904|pubmed:23179078 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6861760|imex:IM-20904-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035038.2|ensembl:ENSMUSG00000030595(gene)|ensembl:ENSMUST00000032815(transcript)|ensembl:ENSMUST00000085851(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q60778|rcsb pdb:1K3Z|rcsb pdb:1OY3|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-445989|reactome:R-MMU-933542|refseq:NP_001293151.1|dip:DIP-37418N ensembl:ENSMUSG00000064145(gene)|ensembl:ENSMUST00000013338(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048588"(developmental cell growth)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071425"(hematopoietic stem cell proliferation)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR031126|interpro:IPR031127|interpro:IPR044066|reactome:R-MMU-983168|refseq:XP_006511788.1|refseq:NP_035920.1 - - - figure legend:Fig. 6D|agonist:"MG132 (proteasomal inhibitor)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2013/06/17 2014/10/16 rogid:ldopxAYCbS48KB25XbB+cotR8Rk10090 rogid:ow+DsLc6ZINTDmmIFreUsU05k5A10090 intact-crc:5921CC2D5CCA4F73|rigid:lHAB1Eit+jgBNfleANpUFBkR4/E false necessary binding region:310-?|flag tag:?-? his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)