#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P46672 uniprotkb:P46655 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W intact:EBI-18665|uniprotkb:D6VV90|ensemblfungi:YGL245W psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:syec_yeast(display_long)|uniprotkb:GUS1(gene name)|psi-mi:GUS1(display_short)|uniprotkb:YGL245W(locus name)|uniprotkb:G0583(orf name)|uniprotkb:HRB724(orf name)|uniprotkb:P85(gene name synonym)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6555937|imex:IM-18705-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J refseq:NP_011269.2|sgd:S000003214|ensemblfungi:YGL245W(gene)|ensemblfungi:YGL245W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR020061|interpro:IPR036282|rcsb pdb:2HRA|rcsb pdb:2HRK|rcsb pdb:2HSM|dip:DIP-2212N|mint:P46655 - crc64:B0CD64AD564900C7 crc64:EADAD430A2D98974 figure legend:fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 rogid:LIzjXfg5py4sesDCIjajYOt7CKo559292 intact-crc:220AB2D9F6C56DBD|rigid:mUQ4ZnNwMDig2nBqHhDt4Q34pEA false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P46672 uniprotkb:P00958 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W intact:EBI-18762|uniprotkb:D6VV43|ensemblfungi:YGR264C psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:symc_yeast(display_long)|uniprotkb:MES1(gene name)|psi-mi:MES1(display_short)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym)|uniprotkb:YGR264C(locus name) psi-mi:"MI:0071"(molecular sieving) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6555937|imex:IM-18705-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J sgd:S000003496|ensemblfungi:YGR264C(gene)|ensemblfungi:YGR264C_mRNA(transcript)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR018285|interpro:IPR023458|interpro:IPR029038|interpro:IPR033911|interpro:IPR041872|rcsb pdb:2HSN|refseq:NP_011780.3|dip:DIP-2211N|mint:P00958 - crc64:B0CD64AD564900C7 crc64:11679C1AB8BB5E39 figure legend:fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 rogid:PvAM0xuDkTBWYvW5hgi/o4lf/Tw559292 intact-crc:220AB2D9F6C56DBD|rigid:mUQ4ZnNwMDig2nBqHhDt4Q34pEA false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P46672 uniprotkb:P46655 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W intact:EBI-18665|uniprotkb:D6VV90|ensemblfungi:YGL245W psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:syec_yeast(display_long)|uniprotkb:GUS1(gene name)|psi-mi:GUS1(display_short)|uniprotkb:YGL245W(locus name)|uniprotkb:G0583(orf name)|uniprotkb:HRB724(orf name)|uniprotkb:P85(gene name synonym)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6555946|imex:IM-18705-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J refseq:NP_011269.2|sgd:S000003214|ensemblfungi:YGL245W(gene)|ensemblfungi:YGL245W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR020061|interpro:IPR036282|rcsb pdb:2HRA|rcsb pdb:2HRK|rcsb pdb:2HSM|dip:DIP-2212N|mint:P46655 - crc64:B0CD64AD564900C7 crc64:EADAD430A2D98974 figure legend:fig. 2|comment:The reconstituted complexes were formed using tRNAMet and tRNAGlu but these could not be differentiated in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 rogid:LIzjXfg5py4sesDCIjajYOt7CKo559292 intact-crc:1DE174CBF5894F85 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P46672 uniprotkb:P00958 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W intact:EBI-18762|uniprotkb:D6VV43|ensemblfungi:YGR264C psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:symc_yeast(display_long)|uniprotkb:MES1(gene name)|psi-mi:MES1(display_short)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym)|uniprotkb:YGR264C(locus name) psi-mi:"MI:0071"(molecular sieving) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6555946|imex:IM-18705-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J sgd:S000003496|ensemblfungi:YGR264C(gene)|ensemblfungi:YGR264C_mRNA(transcript)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR018285|interpro:IPR023458|interpro:IPR029038|interpro:IPR033911|interpro:IPR041872|rcsb pdb:2HSN|refseq:NP_011780.3|dip:DIP-2211N|mint:P00958 - crc64:B0CD64AD564900C7 crc64:11679C1AB8BB5E39 figure legend:fig. 2|comment:The reconstituted complexes were formed using tRNAMet and tRNAGlu but these could not be differentiated in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 rogid:PvAM0xuDkTBWYvW5hgi/o4lf/Tw559292 intact-crc:1DE174CBF5894F85 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P46672 intact:EBI-6556605 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W chebi:"CHEBI:17843" psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:trna(display_short)|psi-mi:EBI-6556605(display_long) psi-mi:"MI:0071"(molecular sieving) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6555946|imex:IM-18705-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0325"(transfer rna) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J - - crc64:B0CD64AD564900C7 - figure legend:fig. 2|comment:The reconstituted complexes were formed using tRNAMet and tRNAGlu but these could not be differentiated in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 - intact-crc:1DE174CBF5894F85 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P46672 uniprotkb:P46655 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W intact:EBI-18665|uniprotkb:D6VV90|ensemblfungi:YGL245W psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:syec_yeast(display_long)|uniprotkb:GUS1(gene name)|psi-mi:GUS1(display_short)|uniprotkb:YGL245W(locus name)|uniprotkb:G0583(orf name)|uniprotkb:HRB724(orf name)|uniprotkb:P85(gene name synonym)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6556595|imex:IM-18705-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J refseq:NP_011269.2|sgd:S000003214|ensemblfungi:YGL245W(gene)|ensemblfungi:YGL245W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR020061|interpro:IPR036282|rcsb pdb:2HRA|rcsb pdb:2HRK|rcsb pdb:2HSM|dip:DIP-2212N|mint:P46655 - crc64:B0CD64AD564900C7 crc64:EADAD430A2D98974 figure legend:Fig. 5, Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 rogid:LIzjXfg5py4sesDCIjajYOt7CKo559292 intact-crc:0F8C07E0AE62962D|rigid:FpE4QhfjotrFkUeb94TouNKJChQ false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46672 uniprotkb:P46655 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W intact:EBI-18665|uniprotkb:D6VV90|ensemblfungi:YGL245W psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:syec_yeast(display_long)|uniprotkb:GUS1(gene name)|psi-mi:GUS1(display_short)|uniprotkb:YGL245W(locus name)|uniprotkb:G0583(orf name)|uniprotkb:HRB724(orf name)|uniprotkb:P85(gene name synonym)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6555962|imex:IM-18705-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J refseq:NP_011269.2|sgd:S000003214|ensemblfungi:YGL245W(gene)|ensemblfungi:YGL245W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR020061|interpro:IPR036282|rcsb pdb:2HRA|rcsb pdb:2HRK|rcsb pdb:2HSM|dip:DIP-2212N|mint:P46655 - crc64:B0CD64AD564900C7 crc64:EADAD430A2D98974 figure legend:Fig. 5, Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 rogid:LIzjXfg5py4sesDCIjajYOt7CKo559292 intact-crc:495BEF71BC936682 false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46672 uniprotkb:P00958 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W intact:EBI-18762|uniprotkb:D6VV43|ensemblfungi:YGR264C psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:symc_yeast(display_long)|uniprotkb:MES1(gene name)|psi-mi:MES1(display_short)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym)|uniprotkb:YGR264C(locus name) psi-mi:"MI:0826"(x ray scattering) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6555962|imex:IM-18705-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J sgd:S000003496|ensemblfungi:YGR264C(gene)|ensemblfungi:YGR264C_mRNA(transcript)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR018285|interpro:IPR023458|interpro:IPR029038|interpro:IPR033911|interpro:IPR041872|rcsb pdb:2HSN|refseq:NP_011780.3|dip:DIP-2211N|mint:P00958 - crc64:B0CD64AD564900C7 crc64:11679C1AB8BB5E39 figure legend:Fig. 5, Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 rogid:PvAM0xuDkTBWYvW5hgi/o4lf/Tw559292 intact-crc:495BEF71BC936682 false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46672 intact:EBI-6555944 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W chebi:"CHEBI:29175" psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:trnaglu(display_short)|psi-mi:EBI-6555944(display_long) psi-mi:"MI:0826"(x ray scattering) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6555962|imex:IM-18705-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0325"(transfer rna) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J - - crc64:B0CD64AD564900C7 - figure legend:Fig. 5, Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 - intact-crc:495BEF71BC936682 false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46672 intact:EBI-6555942 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W chebi:"CHEBI:29173" psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:trnamet(display_short)|psi-mi:EBI-6555942(display_long) psi-mi:"MI:0826"(x ray scattering) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6555962|imex:IM-18705-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0325"(transfer rna) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J - - crc64:B0CD64AD564900C7 - figure legend:Fig. 5, Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 - intact-crc:495BEF71BC936682 false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46672 uniprotkb:P00958 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W intact:EBI-18762|uniprotkb:D6VV43|ensemblfungi:YGR264C psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:symc_yeast(display_long)|uniprotkb:MES1(gene name)|psi-mi:MES1(display_short)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym)|uniprotkb:YGR264C(locus name) psi-mi:"MI:0826"(x ray scattering) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6556599|imex:IM-18705-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J sgd:S000003496|ensemblfungi:YGR264C(gene)|ensemblfungi:YGR264C_mRNA(transcript)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR018285|interpro:IPR023458|interpro:IPR029038|interpro:IPR033911|interpro:IPR041872|rcsb pdb:2HSN|refseq:NP_011780.3|dip:DIP-2211N|mint:P00958 - crc64:B0CD64AD564900C7 crc64:11679C1AB8BB5E39 figure legend:Fig. 5, Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 rogid:PvAM0xuDkTBWYvW5hgi/o4lf/Tw559292 intact-crc:2983EFB342841B8C|rigid:zeMhjURjIaxhFxnZZND5svmYWaY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46672 uniprotkb:P46655 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W intact:EBI-18665|uniprotkb:D6VV90|ensemblfungi:YGL245W psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:syec_yeast(display_long)|uniprotkb:GUS1(gene name)|psi-mi:GUS1(display_short)|uniprotkb:YGL245W(locus name)|uniprotkb:G0583(orf name)|uniprotkb:HRB724(orf name)|uniprotkb:P85(gene name synonym)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556590|imex:IM-18705-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J refseq:NP_011269.2|sgd:S000003214|ensemblfungi:YGL245W(gene)|ensemblfungi:YGL245W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR020061|interpro:IPR036282|rcsb pdb:2HRA|rcsb pdb:2HRK|rcsb pdb:2HSM|dip:DIP-2212N|mint:P46655 - crc64:B0CD64AD564900C7 crc64:EADAD430A2D98974 figure legend:Fig. 5, Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 rogid:LIzjXfg5py4sesDCIjajYOt7CKo559292 intact-crc:406D79BB440B74A8|rigid:mUQ4ZnNwMDig2nBqHhDt4Q34pEA false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46672 uniprotkb:P00958 intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W intact:EBI-18762|uniprotkb:D6VV43|ensemblfungi:YGR264C psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:symc_yeast(display_long)|uniprotkb:MES1(gene name)|psi-mi:MES1(display_short)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym)|uniprotkb:YGR264C(locus name) psi-mi:"MI:0826"(x ray scattering) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556590|imex:IM-18705-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J sgd:S000003496|ensemblfungi:YGR264C(gene)|ensemblfungi:YGR264C_mRNA(transcript)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR018285|interpro:IPR023458|interpro:IPR029038|interpro:IPR033911|interpro:IPR041872|rcsb pdb:2HSN|refseq:NP_011780.3|dip:DIP-2211N|mint:P00958 - crc64:B0CD64AD564900C7 crc64:11679C1AB8BB5E39 figure legend:Fig. 5, Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 rogid:PvAM0xuDkTBWYvW5hgi/o4lf/Tw559292 intact-crc:406D79BB440B74A8|rigid:mUQ4ZnNwMDig2nBqHhDt4Q34pEA false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-6555942 uniprotkb:P46655 chebi:"CHEBI:29173" intact:EBI-18665|uniprotkb:D6VV90|ensemblfungi:YGL245W psi-mi:trnamet(display_short)|psi-mi:EBI-6555942(display_long) psi-mi:syec_yeast(display_long)|uniprotkb:GUS1(gene name)|psi-mi:GUS1(display_short)|uniprotkb:YGL245W(locus name)|uniprotkb:G0583(orf name)|uniprotkb:HRB724(orf name)|uniprotkb:P85(gene name synonym)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556620|imex:IM-18705-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0325"(transfer rna) psi-mi:"MI:0326"(protein) - refseq:NP_011269.2|sgd:S000003214|ensemblfungi:YGL245W(gene)|ensemblfungi:YGL245W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR020061|interpro:IPR036282|rcsb pdb:2HRA|rcsb pdb:2HRK|rcsb pdb:2HSM|dip:DIP-2212N|mint:P46655 - - crc64:EADAD430A2D98974 figure legend:Fig. 3|comment:A competition assay revealed that a high concentration of tRNAGlu did not influence the binding capacity of tRNAMet to the complex demonstrating that tRNAMet and tRNAGlu both bind to the complex and that both tRNAs were bound independently from each other|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 - rogid:LIzjXfg5py4sesDCIjajYOt7CKo559292 intact-crc:5966BFA7A7F0E13E false 32p radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-6555942 intact:EBI-6555944 chebi:"CHEBI:29173" chebi:"CHEBI:29175" psi-mi:trnamet(display_short)|psi-mi:EBI-6555942(display_long) psi-mi:trnaglu(display_short)|psi-mi:EBI-6555944(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556620|imex:IM-18705-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0325"(transfer rna) psi-mi:"MI:0325"(transfer rna) - - - - - figure legend:Fig. 3|comment:A competition assay revealed that a high concentration of tRNAGlu did not influence the binding capacity of tRNAMet to the complex demonstrating that tRNAMet and tRNAGlu both bind to the complex and that both tRNAs were bound independently from each other|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 - - intact-crc:5966BFA7A7F0E13E false 32p radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-6555942 uniprotkb:P46672 chebi:"CHEBI:29173" intact:EBI-7224|uniprotkb:D6VU41|ensemblfungi:YGL105W psi-mi:trnamet(display_short)|psi-mi:EBI-6555942(display_long) psi-mi:arc1_yeast(display_long)|uniprotkb:ARC1(gene name)|psi-mi:ARC1(display_short)|uniprotkb:G4P1(gene name synonym)|uniprotkb:P42(gene name synonym)|uniprotkb:Acyl-RNA-complex protein 1(gene name synonym)|uniprotkb:GU4 nucleic-binding protein 1(gene name synonym)|uniprotkb:tRNA-interacting factor ARC1(gene name synonym)|uniprotkb:G3085(orf name)|uniprotkb:YGL105W(locus name) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556620|imex:IM-18705-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0325"(transfer rna) psi-mi:"MI:0326"(protein) - refseq:NP_011410.1|sgd:S000003073|mint:P46672|dip:DIP-2210N|ensemblfungi:YGL105W(gene)|ensemblfungi:YGL105W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051351"(positive regulation of ligase activity)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002547(tRNA-binding region)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036282|rcsb pdb:2HQT|rcsb pdb:2HRK|rcsb pdb:2HSM|rcsb pdb:2HSN|rcsb pdb:4R1J - - crc64:B0CD64AD564900C7 figure legend:Fig. 3|comment:A competition assay revealed that a high concentration of tRNAGlu did not influence the binding capacity of tRNAMet to the complex demonstrating that tRNAMet and tRNAGlu both bind to the complex and that both tRNAs were bound independently from each other|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 - rogid:QaHZj8wefIPUJN82kJCTv6RXhj8559292 intact-crc:5966BFA7A7F0E13E false 32p radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) intact:EBI-6555942 uniprotkb:P00958 chebi:"CHEBI:29173" intact:EBI-18762|uniprotkb:D6VV43|ensemblfungi:YGR264C psi-mi:trnamet(display_short)|psi-mi:EBI-6555942(display_long) psi-mi:symc_yeast(display_long)|uniprotkb:MES1(gene name)|psi-mi:MES1(display_short)|uniprotkb:Methionyl-tRNA synthetase(gene name synonym)|uniprotkb:YGR264C(locus name) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Koehler et al. (2013) pubmed:23161686|imex:IM-18705 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6556620|imex:IM-18705-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0325"(transfer rna) psi-mi:"MI:0326"(protein) - sgd:S000003496|ensemblfungi:YGR264C(gene)|ensemblfungi:YGR264C_mRNA(transcript)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|go:"GO:0017102"(methionyl glutamyl tRNA synthetase complex)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR018285|interpro:IPR023458|interpro:IPR029038|interpro:IPR033911|interpro:IPR041872|rcsb pdb:2HSN|refseq:NP_011780.3|dip:DIP-2211N|mint:P00958 - - crc64:11679C1AB8BB5E39 figure legend:Fig. 3|comment:A competition assay revealed that a high concentration of tRNAGlu did not influence the binding capacity of tRNAMet to the complex demonstrating that tRNAMet and tRNAGlu both bind to the complex and that both tRNAs were bound independently from each other|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/07 2014/10/16 - rogid:PvAM0xuDkTBWYvW5hgi/o4lf/Tw559292 intact-crc:5966BFA7A7F0E13E false 32p radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)