#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q04863 uniprotkb:Q9WTK5 intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350 intact:EBI-1209166|ensembl:ENSMUSP00000072859|ensembl:ENSMUSP00000107512|ensembl:ENSMUSP00000157542 psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short) psi-mi:nfkb2_mouse(display_long)|uniprotkb:Nfkb2(gene name)|psi-mi:Nfkb2(display_short)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shih et al. (2012) pubmed:23086447|imex:IM-20869 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6688791|imex:IM-20869-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript) refseq:NP_001170840.1|refseq:NP_062281.1|ensembl:ENSMUST00000073116(transcript)|ensembl:ENSMUST00000111881(transcript)|ensembl:ENSMUST00000236591(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|ensembl:ENSMUSG00000025225(gene)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0034097"(response to cytokine)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q9WTK5|rcsb pdb:3JV5|reactome:R-MMU-1810476|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607761|reactome:R-MMU-5676590|reactome:R-MMU-933542|rcsb pdb:3JV6 - - - figure legend:Fig. 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bmdc)|taxid:10090(Mus musculus bone marrow-derived dendritic cells) - 2013/05/21 2014/10/16 rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090 rogid:gqwGHC5ZE+BEWTMFadYsd3zeIwc10090 intact-crc:8C4D2098EC92F9F4|rigid:+JhmVQV5mNd4rqtkub3PMcbCTOs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q04863 uniprotkb:P25799-PRO_0000030313 intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350 intact:EBI-1209141 psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short) psi-mi:p25799-pro_0000030313(display_long)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shih et al. (2012) pubmed:23086447|imex:IM-20869 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6688791|imex:IM-20869-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript) intact:EBI-643958(chain-parent) - - crc64:0597F8EA07635A94|chain-seq-start:1|chain-seq-end:431 figure legend:Fig. 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bmdc)|taxid:10090(Mus musculus bone marrow-derived dendritic cells) - 2013/05/21 2014/10/16 rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090 rogid:GBuHA+lsDwtLjiLENseU03jblkQ10090 intact-crc:8C4D2098EC92F9F4|rigid:+JhmVQV5mNd4rqtkub3PMcbCTOs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q04863 uniprotkb:O54910 intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350 intact:EBI-6688774|ensembl:ENSMUSP00000024742|uniprotkb:Q3U686|uniprotkb:Q9CZZ9|uniprotkb:Q9D7U3 psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short) psi-mi:ikbe_mouse(display_long)|uniprotkb:Nfkbie(gene name)|psi-mi:Nfkbie(display_short)|uniprotkb:Ikbe(gene name synonym)|uniprotkb:I-kappa-B-epsilon(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shih et al. (2012) pubmed:23086447|imex:IM-20869 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6688791|imex:IM-20869-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript) ensembl:ENSMUST00000024742(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0042942"(D-serine transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-MMU-1169091|ensembl:ENSMUSG00000023947(gene)|refseq:NP_001291885.1|refseq:NP_032716.2 - - - figure legend:Fig. 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bmdc)|taxid:10090(Mus musculus bone marrow-derived dendritic cells) - 2013/05/21 2014/10/16 rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090 rogid:veUomq42FfLJRxuI3GBa1NSzaVE10090 intact-crc:8C4D2098EC92F9F4|rigid:+JhmVQV5mNd4rqtkub3PMcbCTOs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q04863 uniprotkb:Q9Z1E3 intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350 intact:EBI-644427|uniprotkb:Q80ZX5|ensembl:ENSMUSP00000021413|uniprotkb:Q3U9W9|uniprotkb:Q3UB40 psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short) psi-mi:ikba_mouse(display_long)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Nfkbia(gene name)|psi-mi:Nfkbia(display_short)|uniprotkb:Ikba(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shih et al. (2012) pubmed:23086447|imex:IM-20869 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6688791|imex:IM-20869-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript) refseq:NP_035037.2|ensembl:ENSMUSG00000021025(gene)|ensembl:ENSMUST00000021413(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q9Z1E3|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5689880|reactome:R-MMU-9020702|reactome:R-MMU-933542|dip:DIP-36160N - - - figure legend:Fig. 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bmdc)|taxid:10090(Mus musculus bone marrow-derived dendritic cells) - 2013/05/21 2014/10/16 rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090 rogid:9uG+85E5n7tKNUUDcVTK2fH2UOM10090 intact-crc:8C4D2098EC92F9F4|rigid:+JhmVQV5mNd4rqtkub3PMcbCTOs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WTK5 uniprotkb:Q04863 intact:EBI-1209166|ensembl:ENSMUSP00000072859|ensembl:ENSMUSP00000107512|ensembl:ENSMUSP00000157542 intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350 psi-mi:nfkb2_mouse(display_long)|uniprotkb:Nfkb2(gene name)|psi-mi:Nfkb2(display_short)|uniprotkb:DNA-binding factor KBF2(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2(gene name synonym) psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shih et al. (2012) pubmed:23086447|imex:IM-20869 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6691886|imex:IM-20869-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170840.1|refseq:NP_062281.1|ensembl:ENSMUST00000073116(transcript)|ensembl:ENSMUST00000111881(transcript)|ensembl:ENSMUST00000236591(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002268"(follicular dendritic cell differentiation)|go:"GO:0002467"(germinal center formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007568"(aging)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033257"(Bcl3/NF-kappaB2 complex)|ensembl:ENSMUSG00000025225(gene)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR000488(Death)|interpro:IPR002110(Ankyrin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|go:"GO:0034097"(response to cytokine)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011029(DEATH-like)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR020683|interpro:IPR030492|interpro:IPR030497|interpro:IPR032397|interpro:IPR033926|interpro:IPR036770|interpro:IPR037059|mint:Q9WTK5|rcsb pdb:3JV5|reactome:R-MMU-1810476|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607761|reactome:R-MMU-5676590|reactome:R-MMU-933542|rcsb pdb:3JV6 refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript) - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bmdc)|taxid:10090(Mus musculus bone marrow-derived dendritic cells) - 2013/05/21 2014/10/16 rogid:gqwGHC5ZE+BEWTMFadYsd3zeIwc10090 rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090 intact-crc:71A78EAEA87AE5B4|rigid:fld3GPiN1kklyKOxE4iMckY1GBI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Z1E3 uniprotkb:Q04863 intact:EBI-644427|uniprotkb:Q80ZX5|ensembl:ENSMUSP00000021413|uniprotkb:Q3U9W9|uniprotkb:Q3UB40 intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350 psi-mi:ikba_mouse(display_long)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Nfkbia(gene name)|psi-mi:Nfkbia(display_short)|uniprotkb:Ikba(gene name synonym) psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shih et al. (2012) pubmed:23086447|imex:IM-20869 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6691890|imex:IM-20869-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035037.2|ensembl:ENSMUSG00000021025(gene)|ensembl:ENSMUST00000021413(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q9Z1E3|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5689880|reactome:R-MMU-9020702|reactome:R-MMU-933542|dip:DIP-36160N refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript) - - - figure legend:Fig. 2B, S2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bmdc)|taxid:10090(Mus musculus bone marrow-derived dendritic cells) - 2013/05/21 2014/10/16 rogid:9uG+85E5n7tKNUUDcVTK2fH2UOM10090 rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090 intact-crc:D561C4414258B09A|rigid:rw7SloK0Cu6jFSM+APkh7ANJYXU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O54910 uniprotkb:Q04863 intact:EBI-6688774|ensembl:ENSMUSP00000024742|uniprotkb:Q3U686|uniprotkb:Q9CZZ9|uniprotkb:Q9D7U3 intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350 psi-mi:ikbe_mouse(display_long)|uniprotkb:Nfkbie(gene name)|psi-mi:Nfkbie(display_short)|uniprotkb:Ikbe(gene name synonym)|uniprotkb:I-kappa-B-epsilon(gene name synonym) psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shih et al. (2012) pubmed:23086447|imex:IM-20869 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6691894|imex:IM-20869-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000024742(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0042942"(D-serine transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-MMU-1169091|ensembl:ENSMUSG00000023947(gene)|refseq:NP_001291885.1|refseq:NP_032716.2 refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript) - - - figure legend:Fig. 2B, S2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bmdc)|taxid:10090(Mus musculus bone marrow-derived dendritic cells) - 2013/05/21 2014/10/16 rogid:veUomq42FfLJRxuI3GBa1NSzaVE10090 rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090 intact-crc:60AB993F36C20593|rigid:2n0Z3lBblCjmjW0LIgmdoNIx8Ps false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q04863 uniprotkb:Q9Z1E3 intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350 intact:EBI-644427|uniprotkb:Q80ZX5|ensembl:ENSMUSP00000021413|uniprotkb:Q3U9W9|uniprotkb:Q3UB40 psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short) psi-mi:ikba_mouse(display_long)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Nfkbia(gene name)|psi-mi:Nfkbia(display_short)|uniprotkb:Ikba(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shih et al. (2012) pubmed:23086447|imex:IM-20869 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6691898|imex:IM-20869-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript) refseq:NP_035037.2|ensembl:ENSMUSG00000021025(gene)|ensembl:ENSMUST00000021413(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q9Z1E3|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5689880|reactome:R-MMU-9020702|reactome:R-MMU-933542|dip:DIP-36160N - - - figure legend:Fig. 3E|antagonist:CpG-unmethylated oligonucleotide - a TLR9 ligand.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bmdc)|taxid:10090(Mus musculus bone marrow-derived dendritic cells) - 2013/05/21 2014/10/16 rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090 rogid:9uG+85E5n7tKNUUDcVTK2fH2UOM10090 intact-crc:56176B26FE1960D3|rigid:rw7SloK0Cu6jFSM+APkh7ANJYXU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P25799-PRO_0000030313 uniprotkb:Q04863 intact:EBI-1209141 intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350 psi-mi:p25799-pro_0000030313(display_long)|uniprotkb:Nfkb1(gene name)|psi-mi:Nfkb1(display_short)|uniprotkb:DNA-binding factor KBF1(gene name synonym)|uniprotkb:EBP-1(gene name synonym)|uniprotkb:NF-kappa-B1 p84/NF-kappa-B1 p98(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1(gene name synonym) psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shih et al. (2012) pubmed:23086447|imex:IM-20869 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6691902|imex:IM-20869-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-643958(chain-parent) refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript) - crc64:0597F8EA07635A94|chain-seq-start:1|chain-seq-end:431 - figure legend:Fig. S2A, S2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bmdc)|taxid:10090(Mus musculus bone marrow-derived dendritic cells) - 2013/05/21 2014/10/16 rogid:GBuHA+lsDwtLjiLENseU03jblkQ10090 rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090 intact-crc:DDE2BBC4A69D5B80|rigid:MeuI/J4u4AODGp2q933OqtjgCg0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Z1E3 uniprotkb:Q04863 intact:EBI-644427|uniprotkb:Q80ZX5|ensembl:ENSMUSP00000021413|uniprotkb:Q3U9W9|uniprotkb:Q3UB40 intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350 psi-mi:ikba_mouse(display_long)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Nfkbia(gene name)|psi-mi:Nfkbia(display_short)|uniprotkb:Ikba(gene name synonym) psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shih et al. (2012) pubmed:23086447|imex:IM-20869 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6691906|imex:IM-20869-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035037.2|ensembl:ENSMUSG00000021025(gene)|ensembl:ENSMUST00000021413(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q9Z1E3|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5689880|reactome:R-MMU-9020702|reactome:R-MMU-933542|dip:DIP-36160N refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript) - - - figure legend:Fig. S2D.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bmdc)|taxid:10090(Mus musculus bone marrow-derived dendritic cells) - 2013/05/21 2014/10/16 rogid:9uG+85E5n7tKNUUDcVTK2fH2UOM10090 rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090 intact-crc:336FC9A4DFC5DC5E|rigid:WBfYbnrubKHDL/6Cnq6Rb+/9U/8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Z1E3 uniprotkb:Q04207 intact:EBI-644427|uniprotkb:Q80ZX5|ensembl:ENSMUSP00000021413|uniprotkb:Q3U9W9|uniprotkb:Q3UB40 intact:EBI-644400|uniprotkb:Q62025|ensembl:ENSMUSP00000025867 psi-mi:ikba_mouse(display_long)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Nfkbia(gene name)|psi-mi:Nfkbia(display_short)|uniprotkb:Ikba(gene name synonym) psi-mi:tf65_mouse(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:Nfkb3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shih et al. (2012) pubmed:23086447|imex:IM-20869 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0974"(InnateDB) intact:EBI-6691906|imex:IM-20869-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035037.2|ensembl:ENSMUSG00000021025(gene)|ensembl:ENSMUST00000021413(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q9Z1E3|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-202424|reactome:R-MMU-209560|reactome:R-MMU-2871837|reactome:R-MMU-445989|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5689880|reactome:R-MMU-9020702|reactome:R-MMU-933542|dip:DIP-36160N refseq:NP_033071.1|reactome:R-MMU-2871837|reactome:R-MMU-3134963|reactome:R-MMU-3214841|reactome:R-MMU-445989|reactome:R-MMU-448706|reactome:R-MMU-4755510|reactome:R-MMU-5607764|reactome:R-MMU-5621575|reactome:R-MMU-9020702|reactome:R-MMU-933542|rcsb pdb:2RAM|rcsb pdb:5U01|rcsb pdb:6GGR|reactome:R-MMU-1169091|reactome:R-MMU-1810476|reactome:R-MMU-193692|reactome:R-MMU-202424|reactome:R-MMU-209560|ensembl:ENSMUSG00000024927(gene)|ensembl:ENSMUST00000025867(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|mint:Q04207|rcsb pdb:1BFT|rcsb pdb:1IKN|rcsb pdb:1K3Z|rcsb pdb:1LE5|rcsb pdb:1LE9|rcsb pdb:1LEI|rcsb pdb:1MY5|rcsb pdb:1MY7|rcsb pdb:1OY3|rcsb pdb:1RAM|interpro:IPR037059|rcsb pdb:1VKX|rcsb pdb:2I9T|rcsb pdb:2LWW|dip:DIP-6219N - - - figure legend:Fig. S2D.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-bmdc)|taxid:10090(Mus musculus bone marrow-derived dendritic cells) - 2013/05/21 2014/10/16 rogid:9uG+85E5n7tKNUUDcVTK2fH2UOM10090 rogid:poiJSPJwXK2Om5pfk8z5HwFgK1o10090 intact-crc:336FC9A4DFC5DC5E|rigid:WBfYbnrubKHDL/6Cnq6Rb+/9U/8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)