#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P01236	uniprotkb:P16471-7	intact:EBI-6903064|ensembl:ENSP00000302150|uniprotkb:Q15199|uniprotkb:Q92996	intact:EBI-6903057|ensembl:ENSP00000311613|ensembl:ENSP00000422935	psi-mi:prl_human(display_long)|uniprotkb:PRL(gene name)|psi-mi:PRL(display_short)	psi-mi:p16471-7(display_long)|uniprotkb:Delta 7/11(isoform synonym)|uniprotkb:PRLR(gene name)|psi-mi:PRLR(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Fleming et al. (2013)	imex:IM-20982|pubmed:23048206	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6903055|imex:IM-20982-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172179(gene)|ensembl:ENST00000306482(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005148"(prolactin receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031904"(endosome lumen)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR001400(Somatotropin hormone)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR018116|rcsb pdb:1RW5|rcsb pdb:2Q98|rcsb pdb:3D48|rcsb pdb:3EW3|rcsb pdb:3MZG|rcsb pdb:3N06|rcsb pdb:3N0P|rcsb pdb:3NCB|rcsb pdb:3NCC|rcsb pdb:3NCE|rcsb pdb:3NCF|rcsb pdb:3NPZ|reactome:R-HSA-1170546|reactome:R-HSA-977225|reactome:R-HSA-982772|go:"GO:1903489"(positive regulation of lactation)|refseq:NP_000939.1|refseq:NP_001157030.1|dip:DIP-59635N	intact:EBI-476182(isoform-parent)|ensembl:ENSG00000113494(gene)|ensembl:ENST00000348262(transcript)|ensembl:ENST00000514088(transcript)	-	-	isoform-comment:Splices from exon 7 to exon 11.	figure legend:3A/B|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/29	2014/10/16	rogid:4ojucvdmaBrTTrB4ee/BsXLlv1U9606	rogid:LhfNvGpPtaidIESAo9trBvY6t1o9606	intact-crc:ABE661CFAD022683|rigid:XZWM7UbJJn4P/ayQVSo2CRAjgGo	false	-	flag tag:c-c	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P01236	uniprotkb:P16471-7	intact:EBI-6903064|ensembl:ENSP00000302150|uniprotkb:Q15199|uniprotkb:Q92996	intact:EBI-6903057|ensembl:ENSP00000311613|ensembl:ENSP00000422935	psi-mi:prl_human(display_long)|uniprotkb:PRL(gene name)|psi-mi:PRL(display_short)	psi-mi:p16471-7(display_long)|uniprotkb:Delta 7/11(isoform synonym)|uniprotkb:PRLR(gene name)|psi-mi:PRLR(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fleming et al. (2013)	imex:IM-20982|pubmed:23048206	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6903130|imex:IM-20982-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172179(gene)|ensembl:ENST00000306482(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005148"(prolactin receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031904"(endosome lumen)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR001400(Somatotropin hormone)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR018116|rcsb pdb:1RW5|rcsb pdb:2Q98|rcsb pdb:3D48|rcsb pdb:3EW3|rcsb pdb:3MZG|rcsb pdb:3N06|rcsb pdb:3N0P|rcsb pdb:3NCB|rcsb pdb:3NCC|rcsb pdb:3NCE|rcsb pdb:3NCF|rcsb pdb:3NPZ|reactome:R-HSA-1170546|reactome:R-HSA-977225|reactome:R-HSA-982772|go:"GO:1903489"(positive regulation of lactation)|refseq:NP_000939.1|refseq:NP_001157030.1|dip:DIP-59635N	intact:EBI-476182(isoform-parent)|ensembl:ENSG00000113494(gene)|ensembl:ENST00000348262(transcript)|ensembl:ENST00000514088(transcript)	-	-	isoform-comment:Splices from exon 7 to exon 11.	figure legend:4|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/29	2014/10/16	rogid:4ojucvdmaBrTTrB4ee/BsXLlv1U9606	rogid:LhfNvGpPtaidIESAo9trBvY6t1o9606	intact-crc:64C01CE1C84A2C59|rigid:XZWM7UbJJn4P/ayQVSo2CRAjgGo	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P01236	uniprotkb:P16471-7	intact:EBI-6903064|ensembl:ENSP00000302150|uniprotkb:Q15199|uniprotkb:Q92996	intact:EBI-6903057|ensembl:ENSP00000311613|ensembl:ENSP00000422935	psi-mi:prl_human(display_long)|uniprotkb:PRL(gene name)|psi-mi:PRL(display_short)	psi-mi:p16471-7(display_long)|uniprotkb:Delta 7/11(isoform synonym)|uniprotkb:PRLR(gene name)|psi-mi:PRLR(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fleming et al. (2013)	imex:IM-20982|pubmed:23048206	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6903136|imex:IM-20982-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000172179(gene)|ensembl:ENST00000306482(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005148"(prolactin receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031904"(endosome lumen)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR001400(Somatotropin hormone)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR018116|rcsb pdb:1RW5|rcsb pdb:2Q98|rcsb pdb:3D48|rcsb pdb:3EW3|rcsb pdb:3MZG|rcsb pdb:3N06|rcsb pdb:3N0P|rcsb pdb:3NCB|rcsb pdb:3NCC|rcsb pdb:3NCE|rcsb pdb:3NCF|rcsb pdb:3NPZ|reactome:R-HSA-1170546|reactome:R-HSA-977225|reactome:R-HSA-982772|go:"GO:1903489"(positive regulation of lactation)|refseq:NP_000939.1|refseq:NP_001157030.1|dip:DIP-59635N	intact:EBI-476182(isoform-parent)|ensembl:ENSG00000113494(gene)|ensembl:ENST00000348262(transcript)|ensembl:ENST00000514088(transcript)	-	-	isoform-comment:Splices from exon 7 to exon 11.	figure legend:4|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/29	2014/10/16	rogid:4ojucvdmaBrTTrB4ee/BsXLlv1U9606	rogid:LhfNvGpPtaidIESAo9trBvY6t1o9606	intact-crc:5363FC557D49B43B|rigid:XZWM7UbJJn4P/ayQVSo2CRAjgGo	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P16471-7	uniprotkb:P01236	intact:EBI-6903057|ensembl:ENSP00000311613|ensembl:ENSP00000422935	intact:EBI-6903064|ensembl:ENSP00000302150|uniprotkb:Q15199|uniprotkb:Q92996	psi-mi:p16471-7(display_long)|uniprotkb:Delta 7/11(isoform synonym)|uniprotkb:PRLR(gene name)|psi-mi:PRLR(display_short)	psi-mi:prl_human(display_long)|uniprotkb:PRL(gene name)|psi-mi:PRL(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fleming et al. (2013)	imex:IM-20982|pubmed:23048206	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6903143|imex:IM-20982-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-476182(isoform-parent)|ensembl:ENSG00000113494(gene)|ensembl:ENST00000348262(transcript)|ensembl:ENST00000514088(transcript)	ensembl:ENSG00000172179(gene)|ensembl:ENST00000306482(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005148"(prolactin receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031904"(endosome lumen)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR001400(Somatotropin hormone)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR018116|rcsb pdb:1RW5|rcsb pdb:2Q98|rcsb pdb:3D48|rcsb pdb:3EW3|rcsb pdb:3MZG|rcsb pdb:3N06|rcsb pdb:3N0P|rcsb pdb:3NCB|rcsb pdb:3NCC|rcsb pdb:3NCE|rcsb pdb:3NCF|rcsb pdb:3NPZ|reactome:R-HSA-1170546|reactome:R-HSA-977225|reactome:R-HSA-982772|go:"GO:1903489"(positive regulation of lactation)|refseq:NP_000939.1|refseq:NP_001157030.1|dip:DIP-59635N	-	isoform-comment:Splices from exon 7 to exon 11.	-	figure legend:4|comment:"The authors were unable to detect (endogenous  CHO derived )  delta-7/11 when incubated with prolactin and immunoprecipitated with the prolactin antibody."|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/07/29	2014/10/16	rogid:LhfNvGpPtaidIESAo9trBvY6t1o9606	rogid:4ojucvdmaBrTTrB4ee/BsXLlv1U9606	intact-crc:27F8D0E9FF022C39|rigid:XZWM7UbJJn4P/ayQVSo2CRAjgGo	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)