#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53722 uniprotkb:P36046 intact:EBI-8059929|uniprotkb:Q6TQT3|uniprotkb:D6W1J5|intact:MINT-6612003|uniprotkb:Q6TQT4 intact:EBI-26978|uniprotkb:D6VX05|ensemblfungi:YKL195W psi-mi:atp23_yeast(display_long)|uniprotkb:ATP23(gene name)|psi-mi:ATP23(display_short)|uniprotkb:N3212(orf name)|uniprotkb:YNR020C(locus name) psi-mi:mia40_yeast(display_long)|uniprotkb:YKL195W(locus name)|uniprotkb:MIA40(gene name)|psi-mi:MIA40(display_short)|uniprotkb:TIM40(gene name synonym)|uniprotkb:Mitochondrial import inner membrane translocase TIM40(gene name synonym) psi-mi:"MI:0081"(peptide array) Weckbecker et al. (2012) pubmed:22990235|imex:IM-18758|mint:MINT-8411024 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8059923|mint:MINT-8411047|imex:IM-18758-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019165|refseq:NP_014417.3|sgd:S000005303|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0046872"(metal ion binding)|mint:MINT-8411050(identity) refseq:NP_012726.2|sgd:S000001678|mint:P36046|dip:DIP-5432N|ensemblfungi:YKL195W(gene)|ensemblfungi:YKL195W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR010625(CHCH)|interpro:IPR039289|rcsb pdb:2ZXT|rcsb pdb:3A3C|mint:MINT-8411049(identity) - function:"Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes the N-terminal 10 residues of mitochondrial ATPase CF(0) subunit 6 (ATP6) at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of ATP6 with the subunit 9 ring"|comment:mint|comment:homomint crc64:5904E8D0213D6EFA figure legend:f4a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/01/21 2014/10/16 rogid:QmRsg54nB/0lNEGolHMjSYABAKc559292 rogid:h/qutsTcZkAqeNJAcTyWJ3FfTrQ559292 intact-crc:B5AD31DBB0459535|rigid:LPjSNQA6V4GGhHfeAwrO7ICzxHM false binding-associated region:48-70(MINT-8411053) mutation decreasing interaction:318-318(MINT-8411062)|mutation decreasing interaction:315-315(MINT-8411059) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P53722 uniprotkb:P36046 intact:EBI-8059929|uniprotkb:Q6TQT3|uniprotkb:D6W1J5|intact:MINT-6612003|uniprotkb:Q6TQT4 intact:EBI-26978|uniprotkb:D6VX05|ensemblfungi:YKL195W psi-mi:atp23_yeast(display_long)|uniprotkb:ATP23(gene name)|psi-mi:ATP23(display_short)|uniprotkb:N3212(orf name)|uniprotkb:YNR020C(locus name) psi-mi:mia40_yeast(display_long)|uniprotkb:YKL195W(locus name)|uniprotkb:MIA40(gene name)|psi-mi:MIA40(display_short)|uniprotkb:TIM40(gene name synonym)|uniprotkb:Mitochondrial import inner membrane translocase TIM40(gene name synonym) psi-mi:"MI:0081"(peptide array) Weckbecker et al. (2012) pubmed:22990235|imex:IM-18758|mint:MINT-8411024 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8060008|mint:MINT-8411066|imex:IM-18758-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019165|refseq:NP_014417.3|sgd:S000005303|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0046872"(metal ion binding)|mint:MINT-8411068(identity) refseq:NP_012726.2|sgd:S000001678|mint:P36046|dip:DIP-5432N|ensemblfungi:YKL195W(gene)|ensemblfungi:YKL195W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR010625(CHCH)|interpro:IPR039289|rcsb pdb:2ZXT|rcsb pdb:3A3C|mint:MINT-8411072(identity) - function:"Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes the N-terminal 10 residues of mitochondrial ATPase CF(0) subunit 6 (ATP6) at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of ATP6 with the subunit 9 ring"|comment:mint|comment:homomint crc64:5904E8D0213D6EFA figure legend:f4a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/01/21 2014/10/16 rogid:QmRsg54nB/0lNEGolHMjSYABAKc559292 rogid:h/qutsTcZkAqeNJAcTyWJ3FfTrQ559292 intact-crc:FEF6F19858AD6B19|rigid:LPjSNQA6V4GGhHfeAwrO7ICzxHM false binding-associated region:95-110(MINT-8411069) mutation decreasing interaction:315-315(MINT-8411075)|mutation decreasing interaction:318-318(MINT-8411073) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P53722 uniprotkb:P36046 intact:EBI-8059929|uniprotkb:Q6TQT3|uniprotkb:D6W1J5|intact:MINT-6612003|uniprotkb:Q6TQT4 intact:EBI-26978|uniprotkb:D6VX05|ensemblfungi:YKL195W psi-mi:atp23_yeast(display_long)|uniprotkb:ATP23(gene name)|psi-mi:ATP23(display_short)|uniprotkb:N3212(orf name)|uniprotkb:YNR020C(locus name) psi-mi:mia40_yeast(display_long)|uniprotkb:YKL195W(locus name)|uniprotkb:MIA40(gene name)|psi-mi:MIA40(display_short)|uniprotkb:TIM40(gene name synonym)|uniprotkb:Mitochondrial import inner membrane translocase TIM40(gene name synonym) psi-mi:"MI:0081"(peptide array) Weckbecker et al. (2012) pubmed:22990235|imex:IM-18758|mint:MINT-8411024 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8060109|mint:MINT-8411094|imex:IM-18758-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019165|refseq:NP_014417.3|sgd:S000005303|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0046872"(metal ion binding)|mint:MINT-8411096(identity) refseq:NP_012726.2|sgd:S000001678|mint:P36046|dip:DIP-5432N|ensemblfungi:YKL195W(gene)|ensemblfungi:YKL195W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR010625(CHCH)|interpro:IPR039289|rcsb pdb:2ZXT|rcsb pdb:3A3C|mint:MINT-8411100(identity) - function:"Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes the N-terminal 10 residues of mitochondrial ATPase CF(0) subunit 6 (ATP6) at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of ATP6 with the subunit 9 ring"|comment:mint|comment:homomint crc64:5904E8D0213D6EFA figure legend:f4a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/01/21 2014/10/16 rogid:QmRsg54nB/0lNEGolHMjSYABAKc559292 rogid:h/qutsTcZkAqeNJAcTyWJ3FfTrQ559292 intact-crc:39915EADCF8FBB56|rigid:LPjSNQA6V4GGhHfeAwrO7ICzxHM false binding-associated region:173-205(MINT-8411097) mutation decreasing interaction:315-315(MINT-8411103)|mutation decreasing interaction:318-318(MINT-8411101) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P53722 uniprotkb:P36046 intact:EBI-8059929|uniprotkb:Q6TQT3|uniprotkb:D6W1J5|intact:MINT-6612003|uniprotkb:Q6TQT4 intact:EBI-26978|uniprotkb:D6VX05|ensemblfungi:YKL195W psi-mi:atp23_yeast(display_long)|uniprotkb:ATP23(gene name)|psi-mi:ATP23(display_short)|uniprotkb:N3212(orf name)|uniprotkb:YNR020C(locus name) psi-mi:mia40_yeast(display_long)|uniprotkb:YKL195W(locus name)|uniprotkb:MIA40(gene name)|psi-mi:MIA40(display_short)|uniprotkb:TIM40(gene name synonym)|uniprotkb:Mitochondrial import inner membrane translocase TIM40(gene name synonym) psi-mi:"MI:0081"(peptide array) Weckbecker et al. (2012) pubmed:22990235|imex:IM-18758|mint:MINT-8411024 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8060060|mint:MINT-8411080|imex:IM-18758-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019165|refseq:NP_014417.3|sgd:S000005303|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0046872"(metal ion binding)|mint:MINT-8411088(identity) refseq:NP_012726.2|sgd:S000001678|mint:P36046|dip:DIP-5432N|ensemblfungi:YKL195W(gene)|ensemblfungi:YKL195W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR010625(CHCH)|interpro:IPR039289|rcsb pdb:2ZXT|rcsb pdb:3A3C|mint:MINT-8411082(identity) - function:"Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes the N-terminal 10 residues of mitochondrial ATPase CF(0) subunit 6 (ATP6) at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of ATP6 with the subunit 9 ring"|comment:mint|comment:homomint crc64:5904E8D0213D6EFA figure legend:f4a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/01/21 2014/10/16 rogid:QmRsg54nB/0lNEGolHMjSYABAKc559292 rogid:h/qutsTcZkAqeNJAcTyWJ3FfTrQ559292 intact-crc:45DCA1D897FC0477|rigid:LPjSNQA6V4GGhHfeAwrO7ICzxHM false binding-associated region:130-148(MINT-8411089) mutation decreasing interaction:318-318(MINT-8411085)|mutation decreasing interaction:315-315(MINT-8411083) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P53722 uniprotkb:P53722 intact:EBI-8059929|uniprotkb:Q6TQT3|uniprotkb:D6W1J5|intact:MINT-6612003|uniprotkb:Q6TQT4 intact:EBI-8059929|uniprotkb:Q6TQT3|uniprotkb:D6W1J5|intact:MINT-6612003|uniprotkb:Q6TQT4 psi-mi:atp23_yeast(display_long)|uniprotkb:ATP23(gene name)|psi-mi:ATP23(display_short)|uniprotkb:N3212(orf name)|uniprotkb:YNR020C(locus name) psi-mi:atp23_yeast(display_long)|uniprotkb:ATP23(gene name)|psi-mi:ATP23(display_short)|uniprotkb:N3212(orf name)|uniprotkb:YNR020C(locus name) psi-mi:"MI:0067"(light scattering) Weckbecker et al. (2012) pubmed:22990235|imex:IM-18758|mint:MINT-8411024 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8060165|mint:MINT-8411114|imex:IM-18758-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019165|refseq:NP_014417.3|sgd:S000005303|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0046872"(metal ion binding)|mint:MINT-8411133(identity) interpro:IPR019165|refseq:NP_014417.3|sgd:S000005303|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0046872"(metal ion binding)|mint:MINT-8411116(identity) - function:"Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes the N-terminal 10 residues of mitochondrial ATPase CF(0) subunit 6 (ATP6) at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of ATP6 with the subunit 9 ring"|comment:mint|comment:homomint function:"Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes the N-terminal 10 residues of mitochondrial ATPase CF(0) subunit 6 (ATP6) at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of ATP6 with the subunit 9 ring"|comment:mint|comment:homomint comment:homomint|comment:mint|figure legend:f8a sf4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/01/21 2014/10/16 rogid:QmRsg54nB/0lNEGolHMjSYABAKc559292 rogid:QmRsg54nB/0lNEGolHMjSYABAKc559292 intact-crc:5C21A53A974A4C6F|rigid:G9JxDnfSX3H7RXx7YHx7xASopS0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53722 uniprotkb:P36046 intact:EBI-8059929|uniprotkb:Q6TQT3|uniprotkb:D6W1J5|intact:MINT-6612003|uniprotkb:Q6TQT4 intact:EBI-26978|uniprotkb:D6VX05|ensemblfungi:YKL195W psi-mi:atp23_yeast(display_long)|uniprotkb:ATP23(gene name)|psi-mi:ATP23(display_short)|uniprotkb:N3212(orf name)|uniprotkb:YNR020C(locus name) psi-mi:mia40_yeast(display_long)|uniprotkb:YKL195W(locus name)|uniprotkb:MIA40(gene name)|psi-mi:MIA40(display_short)|uniprotkb:TIM40(gene name synonym)|uniprotkb:Mitochondrial import inner membrane translocase TIM40(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Weckbecker et al. (2012) pubmed:22990235|imex:IM-18758|mint:MINT-8411024 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8060194|mint:MINT-8411137|imex:IM-18758-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019165|refseq:NP_014417.3|sgd:S000005303|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0046872"(metal ion binding)|mint:MINT-8411139(identity) refseq:NP_012726.2|sgd:S000001678|mint:P36046|dip:DIP-5432N|ensemblfungi:YKL195W(gene)|ensemblfungi:YKL195W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR010625(CHCH)|interpro:IPR039289|rcsb pdb:2ZXT|rcsb pdb:3A3C|mint:MINT-8411143(identity) - function:"Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes the N-terminal 10 residues of mitochondrial ATPase CF(0) subunit 6 (ATP6) at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of ATP6 with the subunit 9 ring"|comment:mint|comment:homomint crc64:5904E8D0213D6EFA figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/01/21 2014/10/16 rogid:QmRsg54nB/0lNEGolHMjSYABAKc559292 rogid:h/qutsTcZkAqeNJAcTyWJ3FfTrQ559292 intact-crc:EC5EF98327D0BCFB|rigid:LPjSNQA6V4GGhHfeAwrO7ICzxHM false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:O74700 uniprotkb:P36046 intact:EBI-9108|ensemblfungi:YEL020W-A|uniprotkb:D3DLM8 intact:EBI-26978|uniprotkb:D6VX05|ensemblfungi:YKL195W psi-mi:tim9_yeast(display_long)|uniprotkb:YEL020BW(orf name)|uniprotkb:YEL020W-A(locus name)|uniprotkb:TIM9(gene name)|psi-mi:TIM9(display_short) psi-mi:mia40_yeast(display_long)|uniprotkb:YKL195W(locus name)|uniprotkb:MIA40(gene name)|psi-mi:MIA40(display_short)|uniprotkb:TIM40(gene name synonym)|uniprotkb:Mitochondrial import inner membrane translocase TIM40(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Weckbecker et al. (2012) pubmed:22990235|imex:IM-18758|mint:MINT-8411024 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8060207|mint:MINT-8411155|imex:IM-18758-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YEL020W-A(gene)|ensemblfungi:YEL020W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0042721"(TIM22 mitochondrial import inner membrane insertion complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|rcsb pdb:3DXR|rcsb pdb:6LO8|reactome:R-SCE-1268020|refseq:NP_010894.1|sgd:S000007256|dip:DIP-5806N|mint:MINT-8411159(identity) refseq:NP_012726.2|sgd:S000001678|mint:P36046|dip:DIP-5432N|ensemblfungi:YKL195W(gene)|ensemblfungi:YKL195W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR010625(CHCH)|interpro:IPR039289|rcsb pdb:2ZXT|rcsb pdb:3A3C|mint:MINT-8411157(identity) - - crc64:5904E8D0213D6EFA figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/01/21 2014/10/16 rogid:UTQs5AY+vpQnYb9+H7M22ha8VWs559292 rogid:h/qutsTcZkAqeNJAcTyWJ3FfTrQ559292 intact-crc:851D4E497CC64B01|rigid:/znWRKJDCTSDtYLMVulWCvd2Qdk false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)