#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32248 uniprotkb:P20963 intact:EBI-3401578|ensembl:ENSP00000246657 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 psi-mi:ccr7_human(display_long)|uniprotkb:CCR7(gene name)|psi-mi:CCR7(display_short)|uniprotkb:CMKBR7(gene name synonym)|uniprotkb:EBI1(gene name synonym)|uniprotkb:EVI1(gene name synonym)|uniprotkb:BLR2(gene name synonym)|uniprotkb:CDw197(gene name synonym)|uniprotkb:Epstein-Barr virus-induced G-protein coupled receptor 1(gene name synonym)|uniprotkb:MIP-3 beta receptor(gene name synonym) psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Martín-Cófreces et al. (2012) pubmed:22922463|mint:MINT-8409790 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8038929|mint:MINT-8409798 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|ensembl:ENSG00000126353(gene)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|ensembl:ENST00000246657(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0002408"(myeloid dendritic cell chemotaxis)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031529"(ruffle organization)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002885"(positive regulation of hypersensitivity)|go:"GO:0002922"(positive regulation of humoral immune response)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0005739"(mitochondrion)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0005886"(plasma membrane)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035757"("chemokine (C-C motif) ligand 19 binding")|go:"GO:0038117"(C-C motif chemokine 19 receptor activity)|go:"GO:0038121"(C-C motif chemokine 21 receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071731"(response to nitric oxide)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097022"(lymphocyte migration into lymph node)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000522"(positive regulation of immunological synapse formation)|go:"GO:2000525"(positive regulation of T cell costimulation)|go:"GO:2000526"(positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation)|go:"GO:2000547"(regulation of dendritic cell dendrite assembly)|go:"GO:2000669"(negative regulation of dendritic cell apoptotic process)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|go:"GO:0035758"("chemokine (C-C motif) ligand 21 binding")|interpro:IPR001718(C-C chemokine receptor, type 7)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6QZH|reactome:R-HSA-380108|reactome:R-HSA-418594|refseq:NP_001829.1|refseq:NP_001288643.1|refseq:NP_001288645.1|refseq:NP_001288646.1|refseq:NP_001288647.1|dip:DIP-5855N|mint:MINT-8409800(identity) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|mint:MINT-8409801(identity) - - - comment:homomint|comment:mint|figure legend:f1e f1d taxid:9606(human-ch7c17 t cells)|taxid:9606(Homo sapiens) - 2013/01/15 2014/10/16 rogid:dfneBfr/6GxvjUI8dc9dUsqQWp09606 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 intact-crc:96E02E7F3A13E48F|rigid:yRwjIqNGYsM9/5bxLRikrj0LUF4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47774 uniprotkb:P20963 intact:EBI-8038963|uniprotkb:Q8CAS2|intact:UNK-5378420|ensembl:ENSMUSP00000099423 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 psi-mi:ccr7_mouse(display_long)|uniprotkb:Epstein-Barr virus-induced G-protein coupled receptor 1(gene name synonym)|uniprotkb:Ccr7(gene name)|psi-mi:Ccr7(display_short)|uniprotkb:Cmkbr7(gene name synonym)|uniprotkb:Ebi1(gene name synonym)|uniprotkb:Ebi1h(gene name synonym)|uniprotkb:MIP-3 beta receptor(gene name synonym) psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Martín-Cófreces et al. (2012) pubmed:22922463|mint:MINT-8409790 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8039032|mint:MINT-8409816 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001288642.1|refseq:NP_031745.2|ensembl:ENSMUSG00000037944(gene)|ensembl:ENSMUST00000103134(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0002408"(myeloid dendritic cell chemotaxis)|go:"GO:0002518"(lymphocyte chemotaxis across high endothelial venule)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002649"(regulation of tolerance induction to self antigen)|go:"GO:0002885"(positive regulation of hypersensitivity)|go:"GO:0002922"(positive regulation of humoral immune response)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035757"("chemokine (C-C motif) ligand 19 binding")|go:"GO:0035758"("chemokine (C-C motif) ligand 21 binding")|go:"GO:0038117"(C-C motif chemokine 19 receptor activity)|go:"GO:0038121"(C-C motif chemokine 21 receptor activity)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048535"(lymph node development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071731"(response to nitric oxide)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097022"(lymphocyte migration into lymph node)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000412"(positive regulation of thymocyte migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000522"(positive regulation of immunological synapse formation)|go:"GO:2000525"(positive regulation of T cell costimulation)|go:"GO:2000526"(positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation)|go:"GO:2000547"(regulation of dendritic cell dendrite assembly)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001718(C-C chemokine receptor, type 7)|reactome:R-MMU-380108|reactome:R-MMU-418594|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:MINT-8409820(identity) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|mint:MINT-8409818(identity) - function:Receptor for the MIP-3-beta chemokine|comment:mint|comment:homomint - figure legend:sf1b|comment:homomint|comment:mint taxid:10090(mouse-spleen)|taxid:10090(Mus musculus spleen) - 2013/01/15 2014/10/16 rogid:3MJ41xnL+JSHZr6HqL98gXhMGcg10090 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 intact-crc:799AFA424C168EC8|rigid:O3O0zqE7f+yWcv0Q7sOWmBK9Cac false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47774 uniprotkb:P20963 intact:EBI-8038963|uniprotkb:Q8CAS2|intact:UNK-5378420|ensembl:ENSMUSP00000099423 intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782 psi-mi:ccr7_mouse(display_long)|uniprotkb:Epstein-Barr virus-induced G-protein coupled receptor 1(gene name synonym)|uniprotkb:Ccr7(gene name)|psi-mi:Ccr7(display_short)|uniprotkb:Cmkbr7(gene name synonym)|uniprotkb:Ebi1(gene name synonym)|uniprotkb:Ebi1h(gene name synonym)|uniprotkb:MIP-3 beta receptor(gene name synonym) psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Martín-Cófreces et al. (2012) pubmed:22922463|mint:MINT-8409790 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8039084|mint:MINT-8409833 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001288642.1|refseq:NP_031745.2|ensembl:ENSMUSG00000037944(gene)|ensembl:ENSMUST00000103134(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0002408"(myeloid dendritic cell chemotaxis)|go:"GO:0002518"(lymphocyte chemotaxis across high endothelial venule)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002649"(regulation of tolerance induction to self antigen)|go:"GO:0002885"(positive regulation of hypersensitivity)|go:"GO:0002922"(positive regulation of humoral immune response)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035757"("chemokine (C-C motif) ligand 19 binding")|go:"GO:0035758"("chemokine (C-C motif) ligand 21 binding")|go:"GO:0038117"(C-C motif chemokine 19 receptor activity)|go:"GO:0038121"(C-C motif chemokine 21 receptor activity)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048535"(lymph node development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071731"(response to nitric oxide)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097022"(lymphocyte migration into lymph node)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|go:"GO:2000107"(negative regulation of leukocyte apoptotic process)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000412"(positive regulation of thymocyte migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000522"(positive regulation of immunological synapse formation)|go:"GO:2000525"(positive regulation of T cell costimulation)|go:"GO:2000526"(positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation)|go:"GO:2000547"(regulation of dendritic cell dendrite assembly)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001718(C-C chemokine receptor, type 7)|reactome:R-MMU-380108|reactome:R-MMU-418594|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:MINT-8409835(identity) refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|mint:MINT-8409837(identity) - function:Receptor for the MIP-3-beta chemokine|comment:mint|comment:homomint - comment:homomint|comment:mint|figure legend:sf1c sf1d sf1e taxid:10090(mouse-spleen)|taxid:10090(Mus musculus spleen) - 2013/01/15 2014/10/16 rogid:3MJ41xnL+JSHZr6HqL98gXhMGcg10090 rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606 intact-crc:4AC6DD56B0C94DAA|rigid:O3O0zqE7f+yWcv0Q7sOWmBK9Cac false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32248 uniprotkb:P07766 intact:EBI-3401578|ensembl:ENSP00000246657 intact:EBI-1211297|uniprotkb:A8K997|intact:EBI-28973315|ensembl:ENSP00000354566 psi-mi:ccr7_human(display_long)|uniprotkb:CCR7(gene name)|psi-mi:CCR7(display_short)|uniprotkb:CMKBR7(gene name synonym)|uniprotkb:EBI1(gene name synonym)|uniprotkb:EVI1(gene name synonym)|uniprotkb:BLR2(gene name synonym)|uniprotkb:CDw197(gene name synonym)|uniprotkb:Epstein-Barr virus-induced G-protein coupled receptor 1(gene name synonym)|uniprotkb:MIP-3 beta receptor(gene name synonym) psi-mi:cd3e_human(display_long)|uniprotkb:CD3E(gene name)|psi-mi:CD3E(display_short)|uniprotkb:T3E(gene name synonym)|uniprotkb:T-cell surface antigen T3/Leu-4 epsilon chain(gene name synonym) psi-mi:"MI:0018"(two hybrid) Martín-Cófreces et al. (2012) pubmed:22922463|mint:MINT-8409790 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8039155|mint:MINT-8409807 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|ensembl:ENSG00000126353(gene)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|ensembl:ENST00000246657(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0002408"(myeloid dendritic cell chemotaxis)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031529"(ruffle organization)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002885"(positive regulation of hypersensitivity)|go:"GO:0002922"(positive regulation of humoral immune response)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0005739"(mitochondrion)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0005886"(plasma membrane)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035757"("chemokine (C-C motif) ligand 19 binding")|go:"GO:0038117"(C-C motif chemokine 19 receptor activity)|go:"GO:0038121"(C-C motif chemokine 21 receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071731"(response to nitric oxide)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097022"(lymphocyte migration into lymph node)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000522"(positive regulation of immunological synapse formation)|go:"GO:2000525"(positive regulation of T cell costimulation)|go:"GO:2000526"(positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation)|go:"GO:2000547"(regulation of dendritic cell dendrite assembly)|go:"GO:2000669"(negative regulation of dendritic cell apoptotic process)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|go:"GO:0035758"("chemokine (C-C motif) ligand 21 binding")|interpro:IPR001718(C-C chemokine receptor, type 7)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6QZH|reactome:R-HSA-380108|reactome:R-HSA-418594|refseq:NP_001829.1|refseq:NP_001288643.1|refseq:NP_001288645.1|refseq:NP_001288646.1|refseq:NP_001288647.1|dip:DIP-5855N|mint:MINT-8409811(identity) refseq:NP_000724.1|ensembl:ENSP00000354566|ensembl:ENSG00000198851(gene)|ensembl:ENST00000361763(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042110"(T cell activation)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0044297"(cell body)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015484(CD3 gamma and delta chain)|interpro:IPR036179|mint:P07766|rcsb pdb:1A81|rcsb pdb:1SY6|rcsb pdb:1XIW|rcsb pdb:2ROL|rcsb pdb:5QU2|rcsb pdb:6JXR|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-389948|mint:MINT-8409809(identity) - - - figure legend:st1|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/01/15 2014/10/16 rogid:dfneBfr/6GxvjUI8dc9dUsqQWp09606 rogid:9BgUsAHGr15di4bpGeW9UjdzWlE9606 intact-crc:D5F63385CB9AE749|rigid:1qwNmIzuV5MvX+90FdDO2uM4ax4 false fusion protein:?-?(MINT-8409900) fusion protein:?-?(MINT-8409879) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0396"(predetermined participant)