#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P49773 uniprotkb:P49773 intact:EBI-1054330|uniprotkb:Q9H5W8|ensembl:ENSP00000304229 intact:EBI-1054330|uniprotkb:Q9H5W8|ensembl:ENSP00000304229 psi-mi:hint1_human(display_long)|uniprotkb:Protein kinase C inhibitor 1(gene name synonym)|uniprotkb:Protein kinase C-interacting protein 1(gene name synonym)|uniprotkb:HINT1(gene name)|psi-mi:HINT1(display_short)|uniprotkb:HINT(gene name synonym)|uniprotkb:PKCI1(gene name synonym)|uniprotkb:PRKCNH1(gene name synonym)|uniprotkb:Desumoylating isopeptidase HINT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein 1(gene name synonym) psi-mi:hint1_human(display_long)|uniprotkb:Protein kinase C inhibitor 1(gene name synonym)|uniprotkb:Protein kinase C-interacting protein 1(gene name synonym)|uniprotkb:HINT1(gene name)|psi-mi:HINT1(display_short)|uniprotkb:HINT(gene name synonym)|uniprotkb:PKCI1(gene name synonym)|uniprotkb:PRKCNH1(gene name synonym)|uniprotkb:Desumoylating isopeptidase HINT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein 1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Dolot et al. (2012) imex:IM-18687|pubmed:22869114 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-6550527|pdbe:3tw2|imex:IM-18687-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005331.1|go:"GO:0016787"(hydrolase activity)|go:"GO:0043530"(adenosine 5'-monophosphoramidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|mint:P49773|rcsb pdb:1AV5|rcsb pdb:1KPA|rcsb pdb:1KPB|rcsb pdb:1KPC|rcsb pdb:1KPE|rcsb pdb:1KPF|rcsb pdb:3TW2|ensembl:ENSG00000169567(gene)|ensembl:ENST00000304043(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000166"(nucleotide binding)|rcsb pdb:4EQE|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|rcsb pdb:4EQG|go:"GO:0005654"(nucleoplasm)|rcsb pdb:4EQH|rcsb pdb:4ZKL|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0009154"(purine ribonucleotide catabolic process)|rcsb pdb:4ZKV|rcsb pdb:5ED3|rcsb pdb:5ED6|rcsb pdb:5EMT|rcsb pdb:5I2E|rcsb pdb:5I2F|rcsb pdb:5IPB|rcsb pdb:5IPC|rcsb pdb:5IPD|rcsb pdb:5IPE|rcsb pdb:5KLY|rcsb pdb:5KLZ|rcsb pdb:5KM0|rcsb pdb:5KM1|rcsb pdb:5KM2|rcsb pdb:5KM3|rcsb pdb:5KM4|rcsb pdb:5KM6|rcsb pdb:5KMA|rcsb pdb:5KMB|rcsb pdb:5KMC|rcsb pdb:5O8I|rcsb pdb:5WA8|rcsb pdb:5WA9|rcsb pdb:5WAA|rcsb pdb:6B42|rcsb pdb:6G9Z|rcsb pdb:6J53|rcsb pdb:6J58|rcsb pdb:6J5S|rcsb pdb:6J5Z|rcsb pdb:6J64|rcsb pdb:6J65|rcsb pdb:6N3V|rcsb pdb:6N3W|rcsb pdb:6N3X|rcsb pdb:6N3Y|rcsb pdb:6YQM refseq:NP_005331.1|go:"GO:0016787"(hydrolase activity)|go:"GO:0043530"(adenosine 5'-monophosphoramidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|mint:P49773|rcsb pdb:1AV5|rcsb pdb:1KPA|rcsb pdb:1KPB|rcsb pdb:1KPC|rcsb pdb:1KPE|rcsb pdb:1KPF|rcsb pdb:3TW2|ensembl:ENSG00000169567(gene)|ensembl:ENST00000304043(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000166"(nucleotide binding)|rcsb pdb:4EQE|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|rcsb pdb:4EQG|go:"GO:0005654"(nucleoplasm)|rcsb pdb:4EQH|rcsb pdb:4ZKL|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0009154"(purine ribonucleotide catabolic process)|rcsb pdb:4ZKV|rcsb pdb:5ED3|rcsb pdb:5ED6|rcsb pdb:5EMT|rcsb pdb:5I2E|rcsb pdb:5I2F|rcsb pdb:5IPB|rcsb pdb:5IPC|rcsb pdb:5IPD|rcsb pdb:5IPE|rcsb pdb:5KLY|rcsb pdb:5KLZ|rcsb pdb:5KM0|rcsb pdb:5KM1|rcsb pdb:5KM2|rcsb pdb:5KM3|rcsb pdb:5KM4|rcsb pdb:5KM6|rcsb pdb:5KMA|rcsb pdb:5KMB|rcsb pdb:5KMC|rcsb pdb:5O8I|rcsb pdb:5WA8|rcsb pdb:5WA9|rcsb pdb:5WAA|rcsb pdb:6B42|rcsb pdb:6G9Z|rcsb pdb:6J53|rcsb pdb:6J58|rcsb pdb:6J5S|rcsb pdb:6J5Z|rcsb pdb:6J64|rcsb pdb:6J65|rcsb pdb:6N3V|rcsb pdb:6N3W|rcsb pdb:6N3X|rcsb pdb:6N3Y|rcsb pdb:6YQM - - - 3d-resolution:1.38 A|3d-r-factors:"R-factor: 0.123 R-free: 0.161"|figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/22 2014/10/16 rogid:vXotU/cqS8hSHeBmCk30zSQ9k/E9606 rogid:vXotU/cqS8hSHeBmCk30zSQ9k/E9606 intact-crc:E045F164F74183A5|rigid:3bEwT7ZylnpBP7qcCJw6o+B0bmM false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)