#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P22336	uniprotkb:P35187	intact:EBI-14971|uniprotkb:P38906|uniprotkb:D6VPL9|ensemblfungi:YAR007C	intact:EBI-17059|uniprotkb:D6W014|ensemblfungi:YMR190C	psi-mi:rfa1_yeast(display_long)|uniprotkb:RFA1(gene name)|psi-mi:RFA1(display_short)|uniprotkb:BUF2(gene name synonym)|uniprotkb:YAR007C(locus name)|uniprotkb:FUN3(orf name)|uniprotkb:Replication protein A 69 kDa DNA-binding subunit(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:DNA-binding protein BUF2(gene name synonym)|uniprotkb:RPA1(gene name synonym)	psi-mi:sgs1_yeast(display_long)|uniprotkb:SGS1(gene name)|psi-mi:SGS1(display_short)|uniprotkb:TPS1(gene name synonym)|uniprotkb:YMR190C(locus name)|uniprotkb:YM9646.02C(orf name)|uniprotkb:Helicase TPS1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hegnauer et al. (2012)	pubmed:22820947|imex:IM-18756|mint:MINT-8406106	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7984672|mint:MINT-8406114|imex:IM-18756-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009404.1|sgd:S000000065|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68962|reactome:R-SCE-69166|reactome:R-SCE-5655862|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensemblfungi:YAR007C(gene)|ensemblfungi:YAR007C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006260"(DNA replication)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006312"(mitotic recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030491"(heteroduplex formation)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043934"(sporulation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|rcsb pdb:1YNX|rcsb pdb:5M1X|rcsb pdb:5OMB|rcsb pdb:5OMC|rcsb pdb:6I52|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|dip:DIP-2512N|mint:P22336|mint:MINT-8406117(identity)	go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010947"(negative regulation of meiotic joint molecule formation)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005634"(nucleus)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR022758|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|rcsb pdb:1D8B|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_013915.1|sgd:S000004802|ensemblfungi:YMR190C(gene)|ensemblfungi:YMR190C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-2911N|mint:P35187|mint:MINT-8406116(identity)	-	crc64:7EB8DFA6910EF8A8	crc64:0DC320B41756A3C3	comment:homomint|comment:domino|comment:mint|figure legend:f1c f1d sf1a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/01/07	2014/10/16	rogid:g7zFw4pOaeYLHSwBeKICZVqA13I559292	rogid:kSX/9U/Qjnhm6doWBmFCKOC8dJo559292	intact-crc:BC70BC5923C4EF76|rigid:lYGpgtPfqLUTkSPEzq7dhZTHjGo	false	binding-associated region:1-133(MINT-8406130)|fusion protein:?-?(MINT-8406119)	fusion protein:?-?(MINT-8406123)|binding-associated region:404-604(MINT-8406126)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26754	uniprotkb:P35187	intact:EBI-14976|uniprotkb:P38905|uniprotkb:D6W0N3|ensemblfungi:YNL312W	intact:EBI-17059|uniprotkb:D6W014|ensemblfungi:YMR190C	psi-mi:rfa2_yeast(display_long)|uniprotkb:RFA2(gene name)|psi-mi:RFA2(display_short)|uniprotkb:BUF1(gene name synonym)|uniprotkb:YNL312W(locus name)|uniprotkb:N0368(orf name)|uniprotkb:Replication protein A 36 kDa subunit(gene name synonym)|uniprotkb:DNA-binding protein BUF1(gene name synonym)	psi-mi:sgs1_yeast(display_long)|uniprotkb:SGS1(gene name)|psi-mi:SGS1(display_short)|uniprotkb:TPS1(gene name synonym)|uniprotkb:YMR190C(locus name)|uniprotkb:YM9646.02C(orf name)|uniprotkb:Helicase TPS1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hegnauer et al. (2012)	pubmed:22820947|imex:IM-18756|mint:MINT-8406106	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7984699|mint:MINT-8406174|imex:IM-18756-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014087.1|sgd:S000005256|ensemblfungi:YNL312W(gene)|ensemblfungi:YNL312W_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|rcsb pdb:6I52|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68962|reactome:R-SCE-69166|interpro:IPR012340(Nucleic acid-binding, OB-fold)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030491"(heteroduplex formation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|go:"GO:0000781"(chromosome, telomeric region)|dip:DIP-2518N|mint:P26754|mint:MINT-8406176(identity)	go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010947"(negative regulation of meiotic joint molecule formation)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005634"(nucleus)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR022758|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|rcsb pdb:1D8B|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_013915.1|sgd:S000004802|ensemblfungi:YMR190C(gene)|ensemblfungi:YMR190C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-2911N|mint:P35187|mint:MINT-8406183(identity)	-	crc64:F6087501E4E28CC1	crc64:0DC320B41756A3C3	figure legend:sf1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/01/07	2014/10/16	rogid:CsitdDua0N9AQdlJn9I0RNmz3Ts559292	rogid:kSX/9U/Qjnhm6doWBmFCKOC8dJo559292	intact-crc:8EACCFB334102997|rigid:HSqWwYvii8ffAxsuq5SIW/DaDtA	false	fusion protein:?-?(MINT-8406180)	fusion protein:?-?(MINT-8406186)|binding-associated region:290-1180(MINT-8406184)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22216	uniprotkb:P35187	intact:EBI-17843|uniprotkb:D6W3L5|uniprotkb:Q6B1S1|ensemblfungi:YPL153C	intact:EBI-17059|uniprotkb:D6W014|ensemblfungi:YMR190C	psi-mi:rad53_yeast(display_long)|uniprotkb:RAD53(gene name)|psi-mi:RAD53(display_short)|uniprotkb:MEC2(gene name synonym)|uniprotkb:SAD1(gene name synonym)|uniprotkb:Serine-protein kinase 1(gene name synonym)|uniprotkb:SPK1(gene name synonym)|uniprotkb:P2588(orf name)|uniprotkb:YPL153C(locus name)|uniprotkb:CHEK2 homolog(gene name synonym)	psi-mi:sgs1_yeast(display_long)|uniprotkb:SGS1(gene name)|psi-mi:SGS1(display_short)|uniprotkb:TPS1(gene name synonym)|uniprotkb:YMR190C(locus name)|uniprotkb:YM9646.02C(orf name)|uniprotkb:Helicase TPS1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hegnauer et al. (2012)	pubmed:22820947|imex:IM-18756|mint:MINT-8406106	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7984737|mint:MINT-8406326|imex:IM-18756-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015172.1|sgd:S000006074|ensemblfungi:YPL153C(gene)|ensemblfungi:YPL153C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0009202"(deoxyribonucleoside triphosphate biosynthetic process)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016256(Serine/threonine-protein kinase RAD53)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1DMZ|rcsb pdb:1FHQ|rcsb pdb:1FHR|rcsb pdb:1G3G|rcsb pdb:1G6G|rcsb pdb:1J4K|rcsb pdb:1J4L|rcsb pdb:1J4O|rcsb pdb:1J4P|rcsb pdb:1J4Q|rcsb pdb:1K2M|rcsb pdb:1K2N|rcsb pdb:1K3J|rcsb pdb:1K3N|rcsb pdb:1K3Q|rcsb pdb:1QU5|rcsb pdb:2A0T|rcsb pdb:2JQI|rcsb pdb:2JQL|rcsb pdb:2YGV|rcsb pdb:4PDP|rcsb pdb:4PDS|rcsb pdb:5T2F|rcsb pdb:5T2S|rcsb pdb:5XZV|rcsb pdb:5XZW|rcsb pdb:6C4U|dip:DIP-2322N|mint:P22216|mint:MINT-8406328(identity)	go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010947"(negative regulation of meiotic joint molecule formation)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005634"(nucleus)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR022758|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|rcsb pdb:1D8B|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_013915.1|sgd:S000004802|ensemblfungi:YMR190C(gene)|ensemblfungi:YMR190C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-2911N|mint:P35187|mint:MINT-8406335(identity)	-	crc64:84A9612229CA72D1	crc64:0DC320B41756A3C3	figure legend:f6a|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/01/07	2014/10/16	rogid:OU8gjvSvTtvDvk+en1y8hyEjFhI559292	rogid:kSX/9U/Qjnhm6doWBmFCKOC8dJo559292	intact-crc:D17667F73B827C97|rigid:TsATKosAIwDO6cLlPeXCn71zAMM	false	binding-associated region:22-162(MINT-8406329)|fusion protein:?-?(MINT-8406332)	fusion protein:?-?(MINT-8406338)|binding-associated region:404-604(MINT-8406336)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22336	uniprotkb:P35187	intact:EBI-14971|uniprotkb:P38906|uniprotkb:D6VPL9|ensemblfungi:YAR007C	intact:EBI-17059|uniprotkb:D6W014|ensemblfungi:YMR190C	psi-mi:rfa1_yeast(display_long)|uniprotkb:RFA1(gene name)|psi-mi:RFA1(display_short)|uniprotkb:BUF2(gene name synonym)|uniprotkb:YAR007C(locus name)|uniprotkb:FUN3(orf name)|uniprotkb:Replication protein A 69 kDa DNA-binding subunit(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:DNA-binding protein BUF2(gene name synonym)|uniprotkb:RPA1(gene name synonym)	psi-mi:sgs1_yeast(display_long)|uniprotkb:SGS1(gene name)|psi-mi:SGS1(display_short)|uniprotkb:TPS1(gene name synonym)|uniprotkb:YMR190C(locus name)|uniprotkb:YM9646.02C(orf name)|uniprotkb:Helicase TPS1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Hegnauer et al. (2012)	pubmed:22820947|imex:IM-18756|mint:MINT-8406106	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7984774|mint:MINT-8406134|imex:IM-18756-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009404.1|sgd:S000000065|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68962|reactome:R-SCE-69166|reactome:R-SCE-5655862|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensemblfungi:YAR007C(gene)|ensemblfungi:YAR007C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006260"(DNA replication)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006312"(mitotic recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030491"(heteroduplex formation)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043934"(sporulation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|rcsb pdb:1YNX|rcsb pdb:5M1X|rcsb pdb:5OMB|rcsb pdb:5OMC|rcsb pdb:6I52|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|dip:DIP-2512N|mint:P22336|mint:MINT-8406136(identity)	go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010947"(negative regulation of meiotic joint molecule formation)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005634"(nucleus)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR022758|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|rcsb pdb:1D8B|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_013915.1|sgd:S000004802|ensemblfungi:YMR190C(gene)|ensemblfungi:YMR190C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-2911N|mint:P35187|mint:MINT-8406143(identity)	-	crc64:7EB8DFA6910EF8A8	crc64:0DC320B41756A3C3	figure legend:f1e|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:7.0x10^-5(molar)	2013/01/07	2014/10/16	rogid:g7zFw4pOaeYLHSwBeKICZVqA13I559292	rogid:kSX/9U/Qjnhm6doWBmFCKOC8dJo559292	intact-crc:EC935D4E10304B56|rigid:lYGpgtPfqLUTkSPEzq7dhZTHjGo	false	binding-associated region:3-133(MINT-8406137)	binding-associated region:404-485(MINT-8406144)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35187	uniprotkb:P22216	intact:EBI-17059|uniprotkb:D6W014|ensemblfungi:YMR190C	intact:EBI-17843|uniprotkb:D6W3L5|uniprotkb:Q6B1S1|ensemblfungi:YPL153C	psi-mi:sgs1_yeast(display_long)|uniprotkb:SGS1(gene name)|psi-mi:SGS1(display_short)|uniprotkb:TPS1(gene name synonym)|uniprotkb:YMR190C(locus name)|uniprotkb:YM9646.02C(orf name)|uniprotkb:Helicase TPS1(gene name synonym)	psi-mi:rad53_yeast(display_long)|uniprotkb:RAD53(gene name)|psi-mi:RAD53(display_short)|uniprotkb:MEC2(gene name synonym)|uniprotkb:SAD1(gene name synonym)|uniprotkb:Serine-protein kinase 1(gene name synonym)|uniprotkb:SPK1(gene name synonym)|uniprotkb:P2588(orf name)|uniprotkb:YPL153C(locus name)|uniprotkb:CHEK2 homolog(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Hegnauer et al. (2012)	pubmed:22820947|imex:IM-18756|mint:MINT-8406106	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7984816|mint:MINT-8406347|imex:IM-18756-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010947"(negative regulation of meiotic joint molecule formation)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005634"(nucleus)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR022758|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|rcsb pdb:1D8B|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_013915.1|sgd:S000004802|ensemblfungi:YMR190C(gene)|ensemblfungi:YMR190C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-2911N|mint:P35187|mint:MINT-8406357(identity)	refseq:NP_015172.1|sgd:S000006074|ensemblfungi:YPL153C(gene)|ensemblfungi:YPL153C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0009202"(deoxyribonucleoside triphosphate biosynthetic process)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016256(Serine/threonine-protein kinase RAD53)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1DMZ|rcsb pdb:1FHQ|rcsb pdb:1FHR|rcsb pdb:1G3G|rcsb pdb:1G6G|rcsb pdb:1J4K|rcsb pdb:1J4L|rcsb pdb:1J4O|rcsb pdb:1J4P|rcsb pdb:1J4Q|rcsb pdb:1K2M|rcsb pdb:1K2N|rcsb pdb:1K3J|rcsb pdb:1K3N|rcsb pdb:1K3Q|rcsb pdb:1QU5|rcsb pdb:2A0T|rcsb pdb:2JQI|rcsb pdb:2JQL|rcsb pdb:2YGV|rcsb pdb:4PDP|rcsb pdb:4PDS|rcsb pdb:5T2F|rcsb pdb:5T2S|rcsb pdb:5XZV|rcsb pdb:5XZW|rcsb pdb:6C4U|dip:DIP-2322N|mint:P22216|mint:MINT-8406349(identity)	-	crc64:0DC320B41756A3C3	crc64:84A9612229CA72D1	figure legend:f6b|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.1x10^-5(molar)	2013/01/07	2014/10/16	rogid:kSX/9U/Qjnhm6doWBmFCKOC8dJo559292	rogid:OU8gjvSvTtvDvk+en1y8hyEjFhI559292	intact-crc:1F10F861BC6251A0|rigid:TsATKosAIwDO6cLlPeXCn71zAMM	false	phosphorylated residue:451-451(MINT-8406367)|binding-associated region:446-456(MINT-8406360)	binding-associated region:22-162(IPR008984)	-	-	psi-mi:"MI:0083"(peptide synthesis)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22336	uniprotkb:P35187	intact:EBI-14971|uniprotkb:P38906|uniprotkb:D6VPL9|ensemblfungi:YAR007C	intact:EBI-17059|uniprotkb:D6W014|ensemblfungi:YMR190C	psi-mi:rfa1_yeast(display_long)|uniprotkb:RFA1(gene name)|psi-mi:RFA1(display_short)|uniprotkb:BUF2(gene name synonym)|uniprotkb:YAR007C(locus name)|uniprotkb:FUN3(orf name)|uniprotkb:Replication protein A 69 kDa DNA-binding subunit(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:DNA-binding protein BUF2(gene name synonym)|uniprotkb:RPA1(gene name synonym)	psi-mi:sgs1_yeast(display_long)|uniprotkb:SGS1(gene name)|psi-mi:SGS1(display_short)|uniprotkb:TPS1(gene name synonym)|uniprotkb:YMR190C(locus name)|uniprotkb:YM9646.02C(orf name)|uniprotkb:Helicase TPS1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Hegnauer et al. (2012)	pubmed:22820947|imex:IM-18756|mint:MINT-8406106	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7984795|mint:MINT-8406156|imex:IM-18756-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009404.1|sgd:S000000065|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68962|reactome:R-SCE-69166|reactome:R-SCE-5655862|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensemblfungi:YAR007C(gene)|ensemblfungi:YAR007C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006260"(DNA replication)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006312"(mitotic recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030491"(heteroduplex formation)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043934"(sporulation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|rcsb pdb:1YNX|rcsb pdb:5M1X|rcsb pdb:5OMB|rcsb pdb:5OMC|rcsb pdb:6I52|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|dip:DIP-2512N|mint:P22336|mint:MINT-8406163(identity)	go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010947"(negative regulation of meiotic joint molecule formation)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005634"(nucleus)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR022758|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|rcsb pdb:1D8B|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_013915.1|sgd:S000004802|ensemblfungi:YMR190C(gene)|ensemblfungi:YMR190C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-2911N|mint:P35187|mint:MINT-8406159(identity)	-	crc64:7EB8DFA6910EF8A8	crc64:0DC320B41756A3C3	figure legend:f1f|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.4x10^-5(molar)	2013/01/07	2014/10/16	rogid:g7zFw4pOaeYLHSwBeKICZVqA13I559292	rogid:kSX/9U/Qjnhm6doWBmFCKOC8dJo559292	intact-crc:3D436ED980FBE820|rigid:lYGpgtPfqLUTkSPEzq7dhZTHjGo	false	binding-associated region:3-133(MINT-8406164)	binding-associated region:404-560(MINT-8406160)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22336	uniprotkb:P35187	intact:EBI-14971|uniprotkb:P38906|uniprotkb:D6VPL9|ensemblfungi:YAR007C	intact:EBI-17059|uniprotkb:D6W014|ensemblfungi:YMR190C	psi-mi:rfa1_yeast(display_long)|uniprotkb:RFA1(gene name)|psi-mi:RFA1(display_short)|uniprotkb:BUF2(gene name synonym)|uniprotkb:YAR007C(locus name)|uniprotkb:FUN3(orf name)|uniprotkb:Replication protein A 69 kDa DNA-binding subunit(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:DNA-binding protein BUF2(gene name synonym)|uniprotkb:RPA1(gene name synonym)	psi-mi:sgs1_yeast(display_long)|uniprotkb:SGS1(gene name)|psi-mi:SGS1(display_short)|uniprotkb:TPS1(gene name synonym)|uniprotkb:YMR190C(locus name)|uniprotkb:YM9646.02C(orf name)|uniprotkb:Helicase TPS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hegnauer et al. (2012)	pubmed:22820947|imex:IM-18756|mint:MINT-8406106	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7984909|mint:MINT-8406308|imex:IM-18756-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009404.1|sgd:S000000065|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68962|reactome:R-SCE-69166|reactome:R-SCE-5655862|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensemblfungi:YAR007C(gene)|ensemblfungi:YAR007C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006260"(DNA replication)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006312"(mitotic recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030491"(heteroduplex formation)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043934"(sporulation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|rcsb pdb:1YNX|rcsb pdb:5M1X|rcsb pdb:5OMB|rcsb pdb:5OMC|rcsb pdb:6I52|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|dip:DIP-2512N|mint:P22336|mint:MINT-8406310(identity)	go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010947"(negative regulation of meiotic joint molecule formation)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005634"(nucleus)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR022758|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|rcsb pdb:1D8B|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_013915.1|sgd:S000004802|ensemblfungi:YMR190C(gene)|ensemblfungi:YMR190C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-2911N|mint:P35187|mint:MINT-8406314(identity)	-	crc64:7EB8DFA6910EF8A8	crc64:0DC320B41756A3C3	figure legend:sf2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/01/07	2014/10/16	rogid:g7zFw4pOaeYLHSwBeKICZVqA13I559292	rogid:kSX/9U/Qjnhm6doWBmFCKOC8dJo559292	intact-crc:C78F3EAB7A412249|rigid:lYGpgtPfqLUTkSPEzq7dhZTHjGo	false	ha tag:?-?(MINT-8406311)	myc tag:?-?(MINT-8406317)|mutation decreasing interaction:404-604(MINT-8406315)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P35187	uniprotkb:P22336	intact:EBI-17059|uniprotkb:D6W014|ensemblfungi:YMR190C	intact:EBI-14971|uniprotkb:P38906|uniprotkb:D6VPL9|ensemblfungi:YAR007C	psi-mi:sgs1_yeast(display_long)|uniprotkb:SGS1(gene name)|psi-mi:SGS1(display_short)|uniprotkb:TPS1(gene name synonym)|uniprotkb:YMR190C(locus name)|uniprotkb:YM9646.02C(orf name)|uniprotkb:Helicase TPS1(gene name synonym)	psi-mi:rfa1_yeast(display_long)|uniprotkb:RFA1(gene name)|psi-mi:RFA1(display_short)|uniprotkb:BUF2(gene name synonym)|uniprotkb:YAR007C(locus name)|uniprotkb:FUN3(orf name)|uniprotkb:Replication protein A 69 kDa DNA-binding subunit(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:DNA-binding protein BUF2(gene name synonym)|uniprotkb:RPA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hegnauer et al. (2012)	pubmed:22820947|imex:IM-18756|mint:MINT-8406106	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7984887|mint:MINT-8406265|imex:IM-18756-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010947"(negative regulation of meiotic joint molecule formation)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005634"(nucleus)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR022758|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|rcsb pdb:1D8B|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_013915.1|sgd:S000004802|ensemblfungi:YMR190C(gene)|ensemblfungi:YMR190C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-2911N|mint:P35187|mint:MINT-8406271(identity)	refseq:NP_009404.1|sgd:S000000065|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5696397|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-68962|reactome:R-SCE-69166|reactome:R-SCE-5655862|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|ensemblfungi:YAR007C(gene)|ensemblfungi:YAR007C_mRNA(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006260"(DNA replication)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006312"(mitotic recombination)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030491"(heteroduplex formation)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043934"(sporulation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|rcsb pdb:1YNX|rcsb pdb:5M1X|rcsb pdb:5OMB|rcsb pdb:5OMC|rcsb pdb:6I52|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-176187|dip:DIP-2512N|mint:P22336|mint:MINT-8406267(identity)	-	crc64:0DC320B41756A3C3	crc64:7EB8DFA6910EF8A8	figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/01/07	2014/10/16	rogid:kSX/9U/Qjnhm6doWBmFCKOC8dJo559292	rogid:g7zFw4pOaeYLHSwBeKICZVqA13I559292	intact-crc:8DC4AE33B1CC36F7|rigid:lYGpgtPfqLUTkSPEzq7dhZTHjGo	false	mutation decreasing interaction:404-604(MINT-8406283)|myc tag:?-?(MINT-8406272)	ha tag:?-?(MINT-8406268)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35187	uniprotkb:P22216	intact:EBI-17059|uniprotkb:D6W014|ensemblfungi:YMR190C	intact:EBI-17843|uniprotkb:D6W3L5|uniprotkb:Q6B1S1|ensemblfungi:YPL153C	psi-mi:sgs1_yeast(display_long)|uniprotkb:SGS1(gene name)|psi-mi:SGS1(display_short)|uniprotkb:TPS1(gene name synonym)|uniprotkb:YMR190C(locus name)|uniprotkb:YM9646.02C(orf name)|uniprotkb:Helicase TPS1(gene name synonym)	psi-mi:rad53_yeast(display_long)|uniprotkb:RAD53(gene name)|psi-mi:RAD53(display_short)|uniprotkb:MEC2(gene name synonym)|uniprotkb:SAD1(gene name synonym)|uniprotkb:Serine-protein kinase 1(gene name synonym)|uniprotkb:SPK1(gene name synonym)|uniprotkb:P2588(orf name)|uniprotkb:YPL153C(locus name)|uniprotkb:CHEK2 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hegnauer et al. (2012)	pubmed:22820947|imex:IM-18756|mint:MINT-8406106	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7984931|mint:MINT-8406372|imex:IM-18756-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010947"(negative regulation of meiotic joint molecule formation)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005634"(nucleus)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR022758|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|rcsb pdb:1D8B|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_013915.1|sgd:S000004802|ensemblfungi:YMR190C(gene)|ensemblfungi:YMR190C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-2911N|mint:P35187|mint:MINT-8406382(identity)	refseq:NP_015172.1|sgd:S000006074|ensemblfungi:YPL153C(gene)|ensemblfungi:YPL153C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0009202"(deoxyribonucleoside triphosphate biosynthetic process)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016256(Serine/threonine-protein kinase RAD53)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1DMZ|rcsb pdb:1FHQ|rcsb pdb:1FHR|rcsb pdb:1G3G|rcsb pdb:1G6G|rcsb pdb:1J4K|rcsb pdb:1J4L|rcsb pdb:1J4O|rcsb pdb:1J4P|rcsb pdb:1J4Q|rcsb pdb:1K2M|rcsb pdb:1K2N|rcsb pdb:1K3J|rcsb pdb:1K3N|rcsb pdb:1K3Q|rcsb pdb:1QU5|rcsb pdb:2A0T|rcsb pdb:2JQI|rcsb pdb:2JQL|rcsb pdb:2YGV|rcsb pdb:4PDP|rcsb pdb:4PDS|rcsb pdb:5T2F|rcsb pdb:5T2S|rcsb pdb:5XZV|rcsb pdb:5XZW|rcsb pdb:6C4U|dip:DIP-2322N|mint:P22216|mint:MINT-8406374(identity)	-	crc64:0DC320B41756A3C3	crc64:84A9612229CA72D1	figure legend:f6c|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2013/01/07	2014/10/16	rogid:kSX/9U/Qjnhm6doWBmFCKOC8dJo559292	rogid:OU8gjvSvTtvDvk+en1y8hyEjFhI559292	intact-crc:211C00E1CF2230A4|rigid:TsATKosAIwDO6cLlPeXCn71zAMM	false	mutation decreasing interaction:585-585(MINT-8406400)|mutation decreasing interaction:470-470(MINT-8406394)|mutation decreasing interaction:451-451(MINT-8406391)|mutation decreasing interaction:482-482(MINT-8406397)|myc tag:?-?(MINT-8406383)	v5 tag:?-?(MINT-8406375)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)