#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P01011	uniprotkb:P07288	intact:EBI-296557|uniprotkb:Q9UC47|uniprotkb:Q13703|uniprotkb:Q2TU87|uniprotkb:Q2TU88|uniprotkb:Q59GP9|uniprotkb:Q6LBY8|uniprotkb:Q6LDT7|uniprotkb:Q6NSC9|uniprotkb:Q8N177|uniprotkb:Q96DW8|uniprotkb:Q9UNU9|uniprotkb:B3KVQ7|ensembl:ENSP00000376793|ensembl:ENSP00000376795|ensembl:ENSP00000450540	intact:EBI-1220791|uniprotkb:G3XAE3|uniprotkb:Q15096|uniprotkb:Q16272|uniprotkb:Q86TG8|uniprotkb:C9JXH3|uniprotkb:G3V0H4|uniprotkb:Q8IXI4|ensembl:ENSP00000314151	psi-mi:aact_human(display_long)|uniprotkb:Cell growth-inhibiting gene 24/25 protein(gene name synonym)|uniprotkb:SERPINA3(gene name)|psi-mi:SERPINA3(display_short)|uniprotkb:AACT(gene name synonym)|uniprotkb:GIG24(orf name)|uniprotkb:GIG25(orf name)|uniprotkb:Serpin A3(gene name synonym)	psi-mi:klk3_human(display_long)|uniprotkb:KLK3(gene name)|psi-mi:KLK3(display_short)|uniprotkb:APS(gene name synonym)|uniprotkb:Kallikrein-3(gene name synonym)|uniprotkb:Semenogelase(gene name synonym)|uniprotkb:Gamma-seminoprotein(gene name synonym)|uniprotkb:P-30 antigen(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Zhu et al. (2013)	pubmed:22806587|imex:IM-21141	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6925562|imex:IM-21141-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006953"(acute-phase response)|refseq:NP_001076.2|ensembl:ENSG00000196136(gene)|ensembl:ENST00000393078(transcript)|ensembl:ENST00000393080(transcript)|ensembl:ENST00000467132(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|reactome:R-HSA-6798695|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|go:"GO:0006954"(inflammatory response)|interpro:IPR023795|interpro:IPR023796|go:"GO:0010951"(negative regulation of endopeptidase activity)|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01011|rcsb pdb:1AS4|rcsb pdb:1QMN|rcsb pdb:2ACH|rcsb pdb:3CAA|rcsb pdb:3DLW|rcsb pdb:4CAA|rcsb pdb:6HGE|reactome:R-HSA-114608	refseq:NP_001025218.1|refseq:NP_001025219.1|refseq:NP_001639.1|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07288|rcsb pdb:1PFA|rcsb pdb:2PSA|rcsb pdb:2ZCH|rcsb pdb:2ZCK|rcsb pdb:2ZCL|rcsb pdb:3QUM|reactome:R-HSA-381426|reactome:R-HSA-5625886|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|ensembl:ENST00000326003(transcript)|go:"GO:0002803"(positive regulation of antibacterial peptide production)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0030141"(secretory granule)|go:"GO:0031638"(zymogen activation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|ensembl:ENSG00000142515(gene)	-	-	-	figure legend:4|comment:This interaction is negative or dubious at best in normal prostate tissue.|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-prostate_carcinoma)|taxid:9606(Homo sapiens prostate carcinoma)	-	2013/08/12	2014/10/16	rogid:LTdrRsWwtOm8QvOWZ4h0SO8EuP09606	rogid:zHGrnUnp/rNQg9HsI7RMalBX/BE9606	intact-crc:1E97041D26B04A65|rigid:U3YqWy4wiyhqN6MiPVWz6dggFQ0	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)